Dissertations / Theses on the topic 'Milk run'
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Dobler, Manuel Carlos Morais. "Melhoria do processo logístico através de um milk run." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/15096.
Full textOs custos associados aos bens e serviços adquiridos representam um papel importante na tomada de decisão das empresas. É com base nesta importante área da gestão de uma organização, as Compras, que será desenvolvido este trabalho. O presente trabalho analisa as diferentes etapas do processo de abastecimento, pretendendo melhorar e facilitar a gestão das cargas, o abastecimento e receção dos materiais adquiridos e consequentemente reduzir os custos associados com transporte e a contratação de serviços de transporte. É feita uma identificação dos principais problemas encontrados bem como são identificadas oportunidades de melhoria que serão aplicadas à realidade encontrada, tendo sido implementado um método de entregas segundo o modelo Milk Run. Esta alteração trouxe elevadas vantagens ao processo de entregas e redução de custos com transportes tornando o processo mais Lean.
The costs associated with purchased goods and services play an important role in decision making of companies. It is based on this important area of management of an organization, Purchasing, that this work will be developed. This project analyses the different stages of supply and intends to improve and facilitate the management of loads, the supply of purchased goods and consequently reduce the costs associated with transport and hiring transport services. Main problems encountered are described and improvement opportunities identified leading to the implementation of a delivery method according to the Milk Run model. This change brought major advantages to the analysed process of delivery and reduced transport costs making the process leaner.
Nemec, Matej. "Implementace systému Milk Run pro výrobní linky zvolené oblasti." Master's thesis, Vysoké učení technické v Brně. Fakulta podnikatelská, 2018. http://www.nusl.cz/ntk/nusl-377442.
Full textMeyer, Anne [Verfasser]. "Milk Run Design: Definitions, Concepts and Solution Approaches / Anne Meyer." Karlsruhe : KIT Scientific Publishing, 2017. http://www.ksp.kit.edu.
Full textReis, Diogo Oliveira. "Trabalho standard: MTM e ergonomia: normalização de operadores logísticos Milk Run." Master's thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/4523.
Full textMeyer, Anne [Verfasser], and K. [Akademischer Betreuer] Furmans. "Milk Run Design: Definitions, Concepts and Solution Approaches / Anne Meyer. Betreuer: K. Furmans." Karlsruhe : KIT-Bibliothek, 2015. http://d-nb.info/1080246347/34.
Full textMillegård, Jessica, and Sven Kurzbach. "Internal logistics : Optimizing the flow of goods with milk runs." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-10116.
Full textGabellini, Matteo. "Ottimizzazione della logistica inbound ad un impianto industriale in ottica milk run: il caso Biesse S.p.A." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021.
Find full textMontanino, Danilo. "Analisi del parco fornitori e razionalizzazione della logistica inbound mediante milk run : il caso ACMA S.p.A." Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/24775/.
Full textJaroň, Dominik. "Tvorba výrobní koncepce pro zabezpečení výrobního procesu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-400937.
Full textMotta, Rinaldo César Martins. "Análise da cadeia de suprimentos por meio de fornecedores parceiros : estudo de caso em uma empresa do Vale do Paraíba Paulista." Universidade de Taubaté, 2010. http://www.bdtd.unitau.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=553.
Full textThe current process of economic globalization has brought a growing competitiveness for the maintenance and persuit of customers among the companies. Each opportunity that represents competitive advantage has been analyzed and often adopted by several companies. In this context, the suppliers network of the companies may imply a competitive differential as it favors the reduction of costs and the improvement of quality in the acquired production resources. On the other side, delays and/or missing resources in the production chain generate losses of resources and may damage the image of the company in the market. With that aim a study was carried out in the supply chain of a multinational company which makes equipments and machinery in Vale do Paraíba in the state of São Paulo. The development of this work began with the identification of delays and lacks of the resources that come from the supplying chain, as well as, from the process of purchasing and collecting equipment pieces for the system of production then present in the company. In order to reverse the situation, a new purchasing and collecting system that could contribute for the elimination or reduction of those losses was chosen. For that a shared decisive process in the principles of Comakership aligned to the indicative management aiming were adopted. The obtained results have shown the strategic relevance of the integration of the supplying chain. The partnership with suppliers, identification of losses and adoption of a new supplying and collecting system using the Milk Run process, were responsible for the reduction of costs caused by the delays and lack of equipment pieces that used to get the company production stuck among other benefits. The solutions found generated a more stable and lasting relationship with suppliers besides amplifying the competitiveness and survival conditions of the company itself.
Moura, Delmo Alves de. "Caracterização e análise de um sistema de coleta programada de peças, Milk Run, na indústria automobilística nacional." Universidade de São Paulo, 2000. http://www.teses.usp.br/teses/disponiveis/3/3135/tde-29102001-122751/.
Full textThe objective of this dissertation is to feature and analyse the new systems of procurement in Brazilian vehicle industry called Milk Run. This study compares Milk Run, which is a scheduled pick up automobile parts program, picking up automobile parts from several suppliers and returning the reusable containers to suppliers, to Conventional system of procurement (each supplier delivery its automobile parts in the vehicle assembly plant). The analysis is to study the inventory cost in both cases Milk Run and Conventional systems. Another analysis is to understand the role of the supplier, automaker and the logistic provider in Milk Run system and its advantages. Many visits have been necessary to the automakers, suppliers and logistics providers to understand this new situation in Brazil. This dissertation shows that Milk Run system is very close to Just-in-Time system and adopt the same philosophy as: reduction of inventory, increase frequency supply and increase integration between both parts, automaker and supplier. This dissertation tries to contribute to understand the costs included in both system and propose a modeling to compare the costs inherent in Milk Run and Conventional system. This modeling uses the costs defined in the literature about inventory and transportation system depending on the shipment size and one analysis of the Trade-offs in both systems.
Keller, Marielle, and Iris Kuylenstierna. "Future Customer Demand on the Supply Chain and Contribution of the Milk Run Concept at Iggesund Paperboard AB." Thesis, Umeå universitet, Institutionen för matematik och matematisk statistik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-124381.
Full textDarner, Stefan, Leah Lam, and Martin Svensson. "Möjligheter och hinder vid transportkonsolidering : En väg mot cirkulär ekonomi." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-12790.
Full textToday, many transports are at a low rate of utilization. This means that shipping costs per product will be high and at the same time transports have a negative impact on the environment. Consolidating transports can increase the utilization rate for transports which minimizes costs and environmental impact. Increased utilization rates can also help companies move towards circular economics where the goal is to maximize their utilization of resources. However, for small and medium size companies it may be difficult to build up partnerships with other companies. These companies face different possibilities and obstacles in implementing transport consolidation, therefore this study will identify these. The study has been carried out in cooperation with 16 companies in Orust and has shown that the main obstacles to transport consolidation are customer requirements, product requirements and information sharing. The companies perceived that customer demand for short lead times would make it difficult to coordinate transport with other companies. Many companies also found that the productrequirements of their products on transport would make transport consolidation difficult. However, the study showed that several companies had similar product requirements, which enables transport consolidation. Some companies also felt that there was no support and cooperation for the information sharing required for consolidation. The main opportunities identified were corporate culture and the desire to move towards a more sustainable distribution chain. The companies that participated in the interviews mentioned that they can see possibilities of transport consolidation if there was a way to easily coordinate transport. They are also active in the Orust Kretsloppsakademi that works for a sustainable Orust, which shows that there is an interest in becoming more sustainable.
Zhang, Luying, Zhaoyu Hou, and Xiaoying Qiu. "Third party logistics in Chinese automotive industry : a case study of a Chinese automotive manufacturer-Shanghai General Motors." Thesis, Högskolan i Gävle, Avdelningen för Industriell utveckling, IT och Samhällsbyggnad, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-12407.
Full textKuljačková, Tereza. "Optimalizace inbound logistiky u vybrané společnosti v automotivu." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-162799.
Full textMarques, Rúben de Almeida. "Logística de abastecimento de células logísticas." Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/16369.
Full textO ritmo e a exigência dos mercados atuais impõem um sistema logístico ágil e flexível, capaz de responder a novas reivindicações e, simultaneamente, manter um nível de serviço de excelência. Eliminar desperdícios faz parte da melhoria contínua, reduzindo custos e mantendo a organização competitiva. A Bosch Termotecnologia, S.A., também enfrenta estes desafios o que nos levou a identificar a eliminação de desperdícios na cadeia de abastecimento logística, introduzindo ganhos de eficiência e melhorias no nível de serviço ao cliente sem esquecer um aspeto importante, a segurança. Para atingir os ganhos esperados neste projeto, foram aplicadas metodologias de gestão específicas da área de projetos e standarização de processos.
The rhythm and demand of the actual markets, imposes an agile and flexible logistic system, able to respond to new claims and, simultaneously, keep a service level of excellence. To eliminate waste, make part of the continuous improvement, reducing costs and maintaining a competitive organization. Bosch Thermotecnology, S.A., also face this challenges which take us to identify the waste elimination in the logistic supply chain, introducing efficiency gains and improvements at client service level without forgetting an important aspect, security. To achieve the expected gains in this project, it was applied specific management methodologies of the project area and project standardization.
Rehman, Haroon, Sukesh Manthri, Sonia Oad, and Kanishka Chakraborty. "Not Your Regular Run-of-the-Mill Bladder Cancer." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/77.
Full textDas, Arunachal P. "Nonpoint Source Modeling of Indian Run Watershed." Connect to online version at OhioLINK ETD Connect to online version at Digital.Maag, 1999. http://hdl.handle.net/1989/4790.
Full textGeurten, Robert L. "Influence of heart rate monitor on performance in one mile run." < Digital Thesis and Dissertation Collection > Username and password required for access, SU only, 2003. http://www.su.edu/library.digitalthesis/geurtenrobert.pdf.
Full textHu, Zhewei. "Aqua + Culture: Intergrating Fish, Farming, and Flood-control Systems on Four Mile Run." Thesis, Virginia Tech, 2016. http://hdl.handle.net/10919/72227.
Full textMaster of Landscape Architecture
Carver, Melissa. "Nutrient Concentrations and Effects on Mill Run from Residential, Urban, and Industrial Stormwater Contamination." Thesis, NSUWorks, 2019. https://nsuworks.nova.edu/occ_stuetd/505.
Full textBotha, Stefan. "Hybrid non-linear model predictive control of a run-of-mine ore grinding mill circuit." Diss., University of Pretoria, 2018. http://hdl.handle.net/2263/66915.
Full textTo improve controller performance, many studies investigated the inclusion of additional manipulated variables (MVs) in the controller formulation to help control process disturbances, or to provide some form of functional control. Model predictive control (MPC) is considered one of the best advanced process control (APC) techniques and linear MPC controllers have been implemented on grinding mill circuits, while various other advanced controllers have been investigated and tested in simulation. Because of the complexity of grinding mill circuits non-linear MPC (NMPC) controllers have achieved better results in simulations where a wider operating region is required. In the search for additional MVs some researchers have considered including the discrete dynamics as part of the controller formulation instead of segregating them from the APC or base-layer controllers. The discrete dynamics are typically controlled using a layered approach. Discrete dynamics are on/off elements and in the case of a closed-loop grinding mill circuit the discrete elements can be on/off activation variables for feed conveyor belts to select which stockpile is used, selecting whether a secondary grinding stage should be active or not, and switching hydrocyclones in a hydrocyclone cluster. Discrete dynamics are added directly to the APC controllers by using hybrid model predictive control (HMPC). HMPC controllers have been designed for grinding mill circuits, but none of them has considered the switching of hydrocyclones as an additional MV and they only include linear dynamics for the continuous elements. This study addresses this gap by implementing a hybrid NMPC (HNMPC) controller that can switch the hydrocyclones in a cluster.
A commonly used continuous-time grinding mill circuit model with one hydrocyclone is adapted to contain a cluster of hydrocyclones, resulting in a hybrid model. The model parameters are refitted to ensure that the initial design steady-state conditions for the model are still valid with the cluster. The novel contribution of this research is the design of a HNMPC controller using a cluster of hydrocyclones as an additional MV. The HNMPC controller is formulated using the complete nonlinear hybrid model and a genetic algorithm (GA) as the solver. An NMPC controller is also designed and implemented as the base case controller in order to evaluate the HNMPC controller’s performance. To further illustrate the functional control benefits of including the hydrocyclone cluster as an MV, a linear optimisation objective was added to the HNMPC to increase the grinding circuit throughput, while maintaining the quality specification. The results show that the HNMPC controller outperforms the NMPC one in terms of setpoint tracking, disturbance rejection, and process optimisation objectives. The GA is shown to be a good solver for HNMPC, resulting in a robust controller that can still control the plant even when state noise is added to the simulation.
Dissertation (MEng)--University of Pretoria, 2018.
National Research Foundation (DAAD-NRF)
Electrical, Electronic and Computer Engineering
MEng
Unrestricted
Milne, Darren G. "Motivation and its impact on the performance of Special Olympic athletes during the 1.5-mile run." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ53193.pdf.
Full textArsovski, Dragan. "Run-of-the-mill ecology to sexual brutality and evolution : annals of an aroused tortoise population." Thesis, La Rochelle, 2018. http://www.theses.fr/2018LAROS016/document.
Full textTwo populations, island and mainland, of promiscuous sexually coercive Hermann tortoises (Testudo hermanni, a species with delayed maturity ~10 years) from the Prespa Region in Macedonia were scrutinized. Prior maturity, tortoises first grow slowly, thereafter gradually increase growth speed, variation in body size and survival probability (mean annual survival rate: 0.30 to 0.70). Potential for indeterminate growth, progressive hardening of the carapace and a survival plateau at the age of five (0.90) promote inter-individual variations in growth trajectories and a wide range of adult asymptotic sizes. Our data question the classical notion of a given size at maturity; instead progressive raise of testosterone levels suggests that maturity is established in growing males ranging from 115 to 140mm in body length. In the Testudo genus females are larger than males; asymptotic estimates of body size show that the studied populations make no exception. Yet, the largest island tortoises are males. With ~100 individuals/ha and an operational sex ratio (OSR ♂/♀) of ~11, male sexual coercion provokes cloacal injuries to females and reduces their body-condition, increasing female mating costs. Male adult survival (0.97) is greater compared to female survival (0.84). Island females do not live long, are discouraged from reproduction and low recruitment further exacerbates OSR-bias, eventually leading to population extinction. Where females suffer and are underrepresented, frustrated males exhibit frequent same-sex sexual behaviours along with extravagant sexual behaviours. The results are discussed in a conservation framework
McCulloch, Craig Allen. "Characterization of the cooling and transformation of steels on a run-out table of hot-strip mill." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27900.
Full textApplied Science, Faculty of
Materials Engineering, Department of
Graduate
Xiaoming, Jiang. "The evolution of property rights in China : a long-run analysis with special reference to Hefeng textile mill." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284144.
Full textJackson, Bryan K. "A comparison of completion times between a 1.5-mile run on an indoor track and treadmill in physically active individuals /." Read thesis online, 2008. http://library.uco.edu/UCOthesis/JacksonBK2008.pdf.
Full textWood, Melissa A. "The effects of caffeine on ratings of perceived exertion and completion times in a 1.5-mile run test in college-aged males /." Read thesis online, 2007. http://library.uco.edu/UCOthesis/WoodMA2007.pdf.
Full textWeerathunga, Lahiru. "ANALYSIS FOR AN ECONOMICALLY SUITABLE COAL TO PUTTALAM COAL POWER STATION TO RUN THE PLANT IN FULL LOAD CAPACITY." Thesis, Högskolan i Gävle, Avdelningen för bygg- energi- och miljöteknik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-16344.
Full textRicci, Joseph Anthony. ""All Necessary Force": The Coast Guard And The Sinking of the Rum Runner "I'm Alone"." ScholarWorks@UNO, 2011. http://scholarworks.uno.edu/td/1342.
Full textSantos, Maiara da Silva. "Desenvolvimento de métodos de RMN para controle de qualidade de produtos farmacêuticos e agrícolas." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/75/75135/tde-02072014-153817/.
Full textThe need for effective and reliable quality control in products and/or raw materials from pharmaceutical and agricultural industries make analyses of their actives compounds and constituents very important to manufacturers and consumers. Nuclear Magnetic Resonance spectroscopy (NMR) is one of the most important tools for qualitative analysis but it is rarely used as quantitative method. Considering these facts, quantitative NMR methods (qNMR) for analysis of pharmaceutical and agricultural products were developed in this thesis. A high resolution 1H qNMR method for paracetamol, in different pharmaceutical formulations, was validated according to RE Resolution Nº 899. An internal standard was used in this method, therefore, the construction of a calibration curve was unnecessary. Other actives constituents present in the formulations could also be quantified and some excipients, identified. According to NBR 14029, high resolution qNMR 1H and 31P methods were developed and validated for glyphosate. In this case, an external standard was used, which enabled sequential quantitative analyses of different nuclei without the need to prepare a new sample. The high-resolution qNMR 1H was also used as an alternative method for fatty acids determination in oils and olive oils, dispensing transesterifications reactions required for GC analysis. Time domain NMR (TD-NMR) was used to develop a method to detect adulteration of olive oil with soybean oil. This method was based on the viscosity difference between olive oil and soybean oil, and has a great advantage, because it can be applied in sealed packages. Finally, different analytical approaches using high resolution NMR 1H were studied to qualitative and quantitative analysis of milk thistle (Silybum marianum L. Gaertn., Asteraceae), a botanical dietary supplement, enabling the simultaneous quantification of seven active constituents, including two pairs of diastereoisomers. Therefore, it was demonstrated in this thesis the potential of qNMR techniques to quality control of pharmaceutical and agricultural products, with some advantages over other analytical methods, normally used in these analyses.
Bullock, Heather E. "Dirty Talking Cracked Pots: Inferring Function and Use of Decorated Ceramic Bowls at Fourmile Ruin, AZ." BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/2687.
Full textPhaniraj, M. P. "Modeling Constitutive Behavior And Hot Rolling Of Steels." Thesis, Indian Institute of Science, 2004. http://hdl.handle.net/2005/206.
Full textLopez, Nelly, Elin Rickardsson, and Robin Selin. "Behovsanalys i landsbygd : samordning av effektiva och hållbara transporter." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-21255.
Full textThe transport sector currently accounts for about one third of Sweden's total greenhouse gas emissions and together with the European Union's policy, the goal is to reduce the climate impact from a 2-degree target, through a common legislation. Västra Götaland has compiled energy and climate targets, starting in 2030, independence of fossil energy for the western Swedish economy will arise in a sustainable trade and industry. Orust municipality plans to monitor the targets by increasing the proportion of fossil free fuels, increasing the number of public transports, but also reducing the total amount of transport. In many cases, these goals can be achieved through an efficientization of existing resources, and this is what the bachelor thesis gets its actuality. By seeing how and why bus traffic can be coordinated to transport packages and smaller goods with individuals are the objectives of this thesis. In order to investigate the possibility of implementing bus consolidation, extensive literature studies have been carried out, which are based on how different distribution strategies affect the efficiency variables cost, time and load factor. The efficiency variables are considered indirectly through the study but fulfill an important role, as the result is based on how well they are met. In order to further see the possibility of introducing bus consolidation, the study is complemented with qualitative interviews which are aimed at investigating the interest with consolidation at various companies and transporters in the rural area. In order to provide a further dimension of consolidation with bus traffic, a survey was also conducted to study the pupils attitude and behavior towards the subject. Through the theoretical framework, the writers have stated the positive attitude of the companies and operators towards consolidation by bus traffic, in the form of a co-distribution project. By doing this, all participants can make use of bus consolidation as an effective way of shipping frequent deliveries of incoming and outgoing goods. Based on the theoretical framework, three different distribution strategies were formed that are possible to implement in rural areas. Milkrun with oneterminal, was presented as a possible solution in the current situation, since it is timebased and can be performed while buses are not used for other planned routes. However, the study shows that if resources can be added and more companies show interest in bus consolidation, a more suitable transport structure is hub & spoke distribution with milk runs. A more tailor-made transport structure in the form of a hybrid hub & spoke system with milk runs is presented as the most favorable transport system to optimally benefit from the utilization rate of buses. This system requires a more complex information sharing between different actors and is significantly more costly, but in the future it can contribute to the shipment of packages and smaller goods in a sustainable and efficient manner.
Roth, Debra. "The effect of two modes of aerobic assessment on fifth grade students' self efficacy." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3319.
Full textKutnar, Pavel. "Mapování průběhu výroby v elektrotechnické firmě a její optimalizace." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-220024.
Full textJesus, Raphael Amancio. "Cromatografia líquida e análises quimiométricas na diferenciação química de acessos de Lippia alba (Mill) N. E. Brown e potenciais biológicos." Pós-Graduação em Química, 2018. http://ri.ufs.br/jspui/handle/riufs/7920.
Full textThe methodology developed in the present work, through chromatographic fingerprint by LC-DAD and Principal Component Analysis (PCA), was adequate for the chemical differentiation of Lippia alba (Mill) NE Brown accessions, considering the extraction method (infusion and maceration hydroalcoholic) and the collection season (summer and winter), allowing to evaluate the influence of these variables on the chemical composition of extracts obtained. In addition, all extracts were submitted to cytotoxic tests against two tumor cell lines, HL-60 (human leukemia) and HepG2 (human hepatocellular carcinoma), and to inhibition tests against the enzyme acetylcholinesterase (AChE) in order to evaluate the form of extraction and which access is the most promising from a pharmacological point of view. Among the extracts analyzed against tumor cells, eight of them, two from the infusion: 01IW and 02IW and six from the hydroalcoholic extraction: 02HW, 24HW, 39HW, 54HW, 01HS and 24HS, presented better cell inhibition performances against HL-60, with percentage of inhibition between 40.0 and 52.0%, suggesting that these extracts are potentially promising against this lineage. With respect to the anticholinesterase tests, all extracts studied had low AChE inhibitory effect when compared to galantamine (87.4%), highlighting only the samples 01HW (28.4%), 02HW (27.2%), 54HW (29.3%), 01HS (32.7%), 02HS (27.4%) and 24HS (30.3%). Through the analyzes performed by Nuclear Magnetic Resonance (NMR) it was possible to identify the structures of some compounds isolated from this species: flavone tricin and phenylpropanoid verbascoside/isoverbascoside. In addition, the classes of three other metabolites were proposed: two phenylpropanoid derivatives and one flavonoid diglucoside.
A metodologia desenvolvida no presente trabalho, utilizando fingerprint cromatográfico por CL-DAD e Análise de Componentes Principais (PCA), se mostrou adequado para a diferenciação química de acessos de Lippia alba (Mill) N. E. Brown, considerando o método de extração (infusão e maceração hidroalcoólica) e a época de coleta (verão e inverno), permitindo, ainda, avaliar a influência destas variáveis na composição química dos extratos obtidos. Adicionalmente, todos os extratos foram submetidos a testes citotóxicos frente a duas linhagens de células tumorais, HL-60 (leucemia humana) e HepG2 (carcinoma hepatocelular humano), e de inibição enzimática frente a acetilcolinesterase (AChE) com o intuito de avaliar qual a forma de extração e qual acesso é o mais promissor do ponto de vista farmacológico. Entre todos os extratos analisados frente as células tumorais, dois provenientes da infusão: 01II e 02II e seis da extração hidroalcoólica: 02HI, 24HI, 39HI, 54HI, 01HV e 24HV, apresentaram melhores desempenhos de inibição frente a HL-60, com percentual de inibição entre 40,0 e 52,0%, sugerindo que estes extratos são potencialmente promissores contra esta linhagem. Com relação aos testes anticolinesterásicos, todos os extratos estudados apresentaram baixo efeito inibidor da AChE quando comparados a galantamina (87,4%), com destaque para os extratos 01HI (28,4%), 02HI (27,2%), 54HI (29,3%), 01HV (32,7%), 02HV (27,4%) e 24HV (30,3%). Através das análises realizadas por Ressonância Magnética Nuclear (RMN) foi possível identificar as estruturas de alguns dos compostos isolados a partir desta espécie: a flavona tricina e o fenilpropanóide verbascosídeo/isoverbascosídeo. Além disso, foram propostas as classes de outros três metabólitos: dois derivados de fenilpropanóides e um flavonóide diglicosilado.
São Cristóvão, SE
Mansur, Rubina, and Johnson Carolin Svensson. "Kartläggning av interna mjölkrundor : En analys av kartongflöden hos Volvo Lastvagnar Tuve." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-12766.
Full textTo identify how a company's different processes look is an important part of continuousimprovement work. The assignment for this study consists of mapping the daily in-plant milkrunsin one part of the factory, with the goal to make any problems visible. The study deals withlogistics and materials management with a focus on transport and ergonomic aspects that shouldbe in line with Lean thinking. The starting point in this study has been information frominterviews and observations, to provide a good understanding for the in-plant milk-runs. Thestudy includes a brief literature review, onsite observations as well as three in-depth interviews.A comparison was made between the strategy Lean and Volvo's own interpretation of Lean, theVolvo Production System, where the emphasis was highlighted in the standardized approachand that the company standardizes the different workflows to facilitate implementation of theimprovement proposals. The study concludes by formulating proposals on how milk-runsshould look to enable savings in the efficiency perspective and other improvement proposalsthat will benefit the whole company. The author’s conclusion of the thesis work is that there aregood opportunities to positively introduce standardized milk runs for the studied area calledbasmodulen, which will help the company when implementing the improvements.
Gonzalez, Patricia. "Redes de sobrevivência nas ruas de Copacabana: uma casa com 74 cômodos e mais de 140 mil vizinhos." reponame:Repositório Institucional do FGV, 2016. http://hdl.handle.net/10438/16910.
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From the path of Zenita dos Santos Teixeira, black, born in a tribe of Tapuios Indians of Maranhão, and the stories of other individuals on the streets, ethnography, set in the streets of Copacabana, analyzes the dynamics of survival networks, focusing on how they are made, they reproduce and break. The withdrawal of Zenita the sidewalks of the neighborhood in 2012, and the compulsory reception in Abrigo Cristo Redentor, in Bonsucesso, where she lived the last years of his life under the state supervision, enabled the construction of the hypothesis that the networks on the one hand, guarantee the survival of the population called on the streets; but agents and state agencies, often articulated with other social agents who deal with this population, act in order to remove it from the public space, undoing its temporarily or permanently networks
A partir da trajetória de Zenita dos Santos Teixeira, negra, nascida em uma tribo de índios tapuios, no Maranhão, e das histórias de outros indivíduos em situação de rua, a etnografia, ambientada nas ruas de Copacabana, analisa a dinâmica das redes de sobrevivência, focalizando o modo como são constituídas, se reproduzem e se desfazem. A retirada de Zenita das calçadas do bairro, em 2012, e o acolhimento compulsório no Abrigo Cristo Redentor, em Bonsucesso, onde viveu os últimos anos de sua vida sob a tutela do Estado, possibilitou a construção da hipótese de que as redes, por um lado, garantem a sobrevivência da chamada população em situação de rua; porém, agentes e agências estatais, muitas vezes articulados a outros agentes sociais que lidam com esta população, atuam de forma a retirá-la do espaço público, desfazendo suas redes de forma temporária ou definitiva.
Månsson, Jon. "När stadens intryck blir överväldigande : En studie om tillgänglighet och interaktion i stadens olika rum för personer med mental trötthet." Thesis, Umeå universitet, Institutionen för geografi och ekonomisk historia, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121426.
Full textAit-Ali, Abderrahman. "Integration of Production Scheduling and Energy Management : Software Development." Thesis, KTH, Optimeringslära och systemteori, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-160136.
Full textSurovec, Martin. "Obnova areálu Tasovického mlýna." Master's thesis, Vysoké učení technické v Brně. Fakulta architektury, 2015. http://www.nusl.cz/ntk/nusl-216126.
Full textŠkutová, Pavla. "Aromaticky aktivní látky vybraných druhů bylin." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2018. http://www.nusl.cz/ntk/nusl-376780.
Full textSilva, Paula Susana Cardoso Pereira da. "Milk Run : redesenho das linhas de abastecimento." Dissertação, 2008. http://hdl.handle.net/10216/60271.
Full textSilva, Paula Susana Cardoso Pereira da. "Milk Run : redesenho das linhas de abastecimento." Master's thesis, 2008. http://hdl.handle.net/10216/60271.
Full textLiu, li-wei, and 劉力維. "Optimization of Vehicle Routing in the Green Mixed Milk Run Model." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/66312389598729518816.
Full text國立交通大學
交通運輸研究所
100
In recent years, more and more scholars began to study green logistics. This research hopes to combine the green logistics with milk run model and develops the green mixed milk run model. Comparing to the traditional direct line haul system, milk run model emphasizes the small quantities and high frequencies pickup and delivery. This allows each vehicle can maintain a higher loading rate. Because of the frequent replenishment, the warehouse of depot does not have to keep a high inventory level and it brings the inventory cost reduction. That’s why many of the automobile manufacturers achieve the concept of just in time by using milk run model. However, past studies are unable to show the feature of milk run completely when building this model, such as frequent pickup, it represents that milk run model needs to face the problem of multi-period demand. In general, the satellite plants which supply the assembly parts will be set around the automotive assembly plant. Besides, when the car is assembled, it needs to sell to the customer, so mixed delivery and pickup needs to be considered. According to the reasons mentioned above, this study decided to present the milk run model in the way of combing two concepts, VRPPDMTW and IRP. The model of this study mainly determines the routes and the schedule of pickup/delivery. However, the VRP is the NP-Hard problem, so this study uses genetic algorithm as core solver and this study designs those GA mechanisms to prove this study establishes a model allowing the use of genetic algorithm to solve. Finally, this study refers to the international example to design the data input. From the solution, we can find the mixed milk run model can arrange the pickup and delivery schedule according to the assembly speed rate and generate the multi-period routes planning results. Due to the construction of objective function of this study belongs to multiple cost items. So the trade-off effect of each cost items will manipulate the results. To conclude, this study designs two scenarios to prove that when the weight among cost items changed, the model results will be different.
Oliveira, José António Barros. "Implementação de Ferramentas Lean, na Otimização do Abastecimento Logístico - Toyota Caetano." Master's thesis, 2013. http://hdl.handle.net/10316/99654.
Full textNuma Era marcada pela globalização e competitividade, à qual se vem associando uma crise económica global, é fundamental minimizar e/ou eliminar as atividades que não acrescentam valor nas empresas. Uma filosofia direcionada para a melhoria contínua e otimização de processos, tornando-os mais eficazes e mais eficientes, é a base para se atingir a excelência empresarial, possibilitando assim contornar a conjuntura atual. O presente documento foi elaborado na Toyota Caetano Portugal – Departamento de Logística e visa otimizar o processo de abastecimento da linha das cabines (mizusumashi) recorrendo à filosofia e ferramentas Lean. Para tal, iniciou-se o projeto com a análise e estudo do abastecimento da linha numa situação designada de “Situação Inicial”, descrevendo-a ao pormenor. De seguida, realizou-se o levantamento de oportunidades de melhoria, sendo posteriormente implementadas (“Situação Otimizada”). A fim de avaliar e determinar os ganhos alcançados entre as duas situações apresentadas, foram quantificados e comparados a duração de cada rota de abastecimento bem como o número de operações necessárias para a execução das mesmas.
In an age defined by globalization and competitiveness associated with the current global economic crisis, it is essential to minimize and/or to eliminate activities that do not add value to the companies. A philosophy directed to continuous improvement and optimization of processes, making them more effective and efficient, is the basis to achieve business excellence, allowing circumvent the current situation. This document was developed in Toyota Caetano Portugal - Department of Logistics and aims to optimize the cabins supply line (mizusumashi) resorting to Lean tools and philosophy. To accomplish this goal, the project began with the analysis and study of the supply line in a situation designated Initial Situation, describing it in detail. Then, the opportunities for improvement were assessed, and subsequently implemented (Situation Optimized). In order to evaluate and quantify the gains achieved between the two situations presented, the duration of each supply route and the number of operations required to implement them were quantified and compared.
Brandão, Daniel Filipe Oliveira. "Balanceamento e otimização da sequência de saída do armazém dos MILK RUNS." Master's thesis, 2018. http://hdl.handle.net/10773/24372.
Full textThis project, carried out at Bosch Security Systems, shows how a logistics system should be adapted to the company's reality, that is, business strategy - low volume and great diversity. The company in question works in three shifts and has almost 50 production lines. The Milk Run is the means of transport used to take all materials from the warehouse to the productive zone, supplying supermarkets or directly the liners. There are five Milk Runs that perform the filling every 30 minutes. The warehouse exit is the starting point for everyone. It is at this point that everyone synchronizes, allowing them to have a schedule to meet. The fulfilment of these hours is essential for the correct logistic functioning, in this way there will be no waiting times or problems in the circulation of Milk Runs. This project was developed with the objective of improving the calculation of resources allocated monthly to Milk Run. To increase the productivity of the company, the need arose to extend this objective, building a dynamic interface to sequence the warehouse outputs and updating the times associated with tasks of the logistic operator. To fulfil these objectives, several activities were developed, on the factory floor, as time collection and sensitization with the operators to be all aligned with the project objective. At the research level, a research was done in the literature to contextualize all the readers of the terms used throughout the project and to present the perspectives on the theme of the various authors. At the end of this work it is possible to quantify all the improvements developed through the various indicators. Those who make the greatest contribution to the company are the 12% reduction in the Milk Run waiting time in a one-day cycle, a capacity adjustment of 11.1% and a 9.8% improvement in the adhesion rate.
Mestrado em Engenharia e Gestão Industrial
Goncalves, João Pedro Martins. "Revisão dos fluxos de logística interna numa empresa do setor automóvel." Master's thesis, 2020. http://hdl.handle.net/10316/92490.
Full textA crescente exigência do mercado automóvel, leva a que as empresas tenham cada vez mais a necessidade de eliminar desperdícios para tornar os seus processos mais eficientes e dessa forma conseguir fazer mais com menos. Com o objetivo de reduzir desperdícios de stock e movimentação surge a oportunidade deste trabalho com base num problema real, focando-se na redução de stock nas linhas de montagem e na procura de alternativas aos tradicionais meios de movimentação de materiais.Neste trabalho, realizado em parceria com os departamentos de logística e montagem da Iber-Oleff Portugal, foram desenvolvidos métodos de redução de stock na linha de montagem, usando os conceitos presentes nos milk runs internos tais como o Just In Time. Perante a inexistência de documentação relativa à logística interna, surgiu a necessidade da criação de uma base de dados com toda a informação relativa às várias rotas de abastecimento das linhas da Montagem Automotive para que fosse possível perceber o panorama geral do abastecimento e a partir daí perceber as necessidades de melhoria. Durante a recolha de dados, procedeu-se também a um levantamento de problemas durante o processo de abastecimento que culminou com a elaboração de um plano de melhoria contínua. Após uma análise da base de dados, foram encontrados alguns problemas com o dimensionamento do sistema kanban, tendo este sido redimensionado eliminando excesso e evitando quebras de stock. Por fim foi criado um cartão nível com o objetivo de reduzir o stock de material presente nas linhas de montagem.Foram ainda apresentadas sugestões de alternativas aos atuais meios de movimentação e realizados testes com o objetivo de mudar o processo de abastecimento, especializando operadores em tarefas à semelhança do que é feito numa linha de montagem.
The growing demand of the automotive market, leads companies to increasingly need to eliminate waste in order to make their processes more efficient and thus be able to do more with less. In order to reduce waste of stock and handling, the opportunity arises for this work based on a real problem, focusing on stock reduction on assembly lines and looking for alternatives to traditional material handling equipment.In this work, carried out in partnership with the logistics and assembly departments of Iber-Oleff Portugal, were developed methods for reducing stock on the assembly line, using concepts associated with internal milk runs such as Just In Time. Facing a lack of documentation related to internal logistics, the need arose to create a database with all the information related to the various supply routes of the Automotive Assembly lines so that it was possible to understand the general panorama of supply and from there to understand improvement needs. During data collection, problems were also surveyed during the supply process, which culminated in the development of a continuous improvement plan. After an analysis of the database, some problems were found with the sizing of the kanban system, which was resized eliminating excess and avoiding stock breaks. Finally, a level card was created in order to reduce the stock of material present in the assembly lines.Suggestions of alternatives to the current means of movement were also presented and tests were carried out with the aim of changing the supply process, specializing operators in tasks similar to what is done on an assembly line.
"Caracterização e análise de um sistema de coleta programada de peças, Milk Run, na indústria automobilística nacional." Tese, Biblioteca Digital de Teses e Dissertações da USP, 2000. http://www.teses.usp.br/teses/disponiveis/3/3135/tde-29102001-122751/.
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