Relevant bibliographies by topics / Micromixer

Academic literature on the topic 'Micromixer'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 March 2023

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Journal articles on the topic "Micromixer"

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Natsuhara, Daigo, Ryogo Saito, Shunya Okamoto, Moeto Nagai, and Takayuki Shibata. "Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer." Micromachines 13, no. 9 (August 25, 2022): 1386. http://dx.doi.org/10.3390/mi13091386.

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Micromixers are one of the critical components in microfluidic devices. They significantly affect the efficiency and sensitivity of microfluidics-based lab-on-a-chip systems. This study introduces an efficient micromixer with a simple geometrical feature that enables easy incorporation in a microchannel network without compromising the original design of microfluidic devices. The study proposes a newly designed planar passive micromixer, termed a planar asymmetric contraction-and-expansion (P-ACE) micromixer, with asymmetric vertical obstacle structures. Numerical simulation and experimental investigation revealed that the optimally designed P-ACE micromixer exhibited a high mixing efficiency of 80% or more within a microchannel length of 10 mm over a wide range of Reynolds numbers (0.13 ≤ Re ≤ 13), eventually attaining approximately 90% mixing efficiency within a 20 mm microchannel length. The highly asymmetric geometric features of the P-ACE micromixers enhance mixing because of their synergistic effects. The flow velocities and directions of the two fluids change differently while alternately crossing the longitudinal centerline of the microchannel, with the obstacle structures asymmetrically arranged on both sidewalls of the rectangular microchannel. This flow behavior increases the interfacial contact area between the two fluids, thus promoting effective mixing in the P-ACE micromixer. Further, the pressure drops in the P-ACE micromixers were experimentally investigated and compared with those in a serpentine micromixer with a perfectly symmetric mixing unit.
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Zulkarnain, M. H., A. A. Ma’ Radzi, and M. M. Abdul Jamil. "Consideration of Obstacles Configuration in Designing Low Reynolds Number Micromixer for Blood Microfluidic Application." Applied Mechanics and Materials 679 (October 2014): 212–16. http://dx.doi.org/10.4028/www.scientific.net/amm.679.212.

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Micromixer can be divided into two categories which are active micromixer and passive micromixer. Due to the simple fabrication technology and ease of implementation in a complex microfluidic system, obstacle-based passive micromixers will be the focus in this work. A passive micromixer is depends on low Reynolds number and the channel geometry for mixing effectiveness. In this work, three designs of obstacle based micromixer were designed and evaluated. These micromixers has 237μm channel length, 30μm inlet length, 900 between inlets ports, width and depth are 30μm each. The fluids used for mixing were blood which has 3.0 × 10-3 kg/μms of viscosity and glycerin which has high viscosity than blood (1.49 × 10-3 kg/μms). The fluids used to evaluate the differences in term of their visual performance based image’s standard deviation by plotting the graph and mixing efficiency by calculation. Based on these evaluations, the Y shape with meander structure obstacle design has the best mixing efficiency at the outlet of the channel.
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Wang, Chin-Tsan, Yan-Ming Chen, Pei-An Hong, and Yi-Ta Wang. "Tesla Valves in Micromixers." International Journal of Chemical Reactor Engineering 12, no. 1 (January 1, 2014): 397–403. http://dx.doi.org/10.1515/ijcre-2013-0106.

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Abstract Micromixers are the devices which have the ability to mix liquids uniformly. However, a Tesla valve has the potential for micromixer development because of its simple structure and special flow mechanism. In this study, a numerical simulation analysis of a new Tesla-type micromixer was designed by placing a flow plate into a micromixer, which has a contact angle of 30° with the channel wall. The optimization of the geometric parameter, aspect ratio (AR) and the Reynolds number (Re) effect is discussed. The results show that the optimal geometric parameters of the unit Tesla-type micromixer are θ1 = 45°, θ2 = 30°, A = 0.3 mm, B = 0.22 mm, C = 0.3 mm, D = 0.25 mm, and the mixing efficiency can achieve εmixing = 0.953 by passing three-unit Tesla-type micromixers (inverse-type, Re = 1, AR = 1). The Tesla-type micromixers designed in this study, which have a lower pressure drop and a higher mixing performance at a low Reynolds number, can contribute to the application of biomedical chips and chemical reactors.
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Chen, Xue Ye, and Yuan He. "Optimal Design and Simulation for a Bio-Inspired Micromixer Based on Blood Transport in Vessel." Materials Science Forum 852 (April 2016): 1288–92. http://dx.doi.org/10.4028/www.scientific.net/msf.852.1288.

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A novel design concept for micromixer based on blood transport bionic principle has been presented. The bio-inspired micromixer based on blood transport in blood vessel is simulated to obtain a desired mixing efficiency. The flow rate, sample concentration distribution, channel width ratio, and channel arrangement as operating factors were researched to evaluate the mixing performance. The simulation results show the micromixer can give a high performance with the optimized simple structure. The bionic micromixer is proven to be effective for enhancing sample mixing and will have great potential to instruct design of micromixers.
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Khaydarov, Valentin, Ekaterina Borovinskaya, and Wladimir Reschetilowski. "Numerical and Experimental Investigations of a Micromixer with Chicane Mixing Geometry." Applied Sciences 8, no. 12 (December 2, 2018): 2458. http://dx.doi.org/10.3390/app8122458.

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A micromixer is a new type of chemical engineering equipment used to intensify the mixing process. This article provides details on flow regimes in microchannels with a complex geometry, such as with chicane mixing geometry. Experiments involving water, ink, and a micro digital camera have determined both the micromixer’s initial mixing zone, and also the streamlines. Computational fluid dynamics (CFD) modelling helped identify the mechanism of stimulating effect; swirling and recirculation were identified as two special cases of the convective mixing process. To characterize the degree of mixing, a function of volume flow rate was proposed. A much higher degree of mixing in vortex flow compared to stratified flow was observed. The relationship between laminar flow and vortices shows a square-law dependence of pressure drop against the volume flow rate. The mixing cost and the mixing energy cost at Reynolds number of 50 are higher for the chicane micromixer than for micromixers without chicanes geometry.
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Qi, Jia, Wenbo Li, Wei Chu, Jianping Yu, Miao Wu, Youting Liang, Difeng Yin, et al. "A Microfluidic Mixer of High Throughput Fabricated in Glass Using Femtosecond Laser Micromachining Combined with Glass Bonding." Micromachines 11, no. 2 (February 19, 2020): 213. http://dx.doi.org/10.3390/mi11020213.

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We demonstrate a microfluidic mixer of high mixing efficiency in fused silica substrate using femtosecond laser-induced wet etching and hydroxide-catalysis bonding method. The micromixer has a three-dimensional geometry, enabling efficient mixing based on Baker’s transformation principle. The cross-sectional area of the fabricated micromixer was 0.5 × 0.5 mm2, enabling significantly promotion of the throughput of the micromixer. The performance of the fabricated micromixers was evaluated by mixing up blue and yellow ink solutions with a flow rate as high as 6 mL/min.
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Mahmud, Fahizan, Khairul Fikri Tamrin, Shahrol Mohamaddan, and Nobuo Watanabe. "Effect of Thermal Energy and Ultrasonication on Mixing Efficiency in Passive Micromixers." Processes 9, no. 5 (May 18, 2021): 891. http://dx.doi.org/10.3390/pr9050891.

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Micromixing is a key process in microfluidics technology. However, rapid and efficient fluid mixing is difficult to achieve inside the microchannels due to unfavourable laminar flow. Active micromixers employing ultrasound and thermal energy are effective in enhancing the micromixing process; however, integration of these energy sources within the devices is a non-trivial task. In this study, ultrasound and thermal energy have been extraneously applied at the upstream of the micromixer to significantly reduce fabrication complexity. A novel Dean micromixer was laser-fabricated to passively increase mixing performance and compared with T- and Y-micromixers at Reynolds numbers between 5 to 100. The micromixers had a relatively higher mixing index at lower Reynolds number, attributed to higher residence time. Dean micromixer exhibits higher mixing performance (about 27% better) than T- and Y-micromixers for 40 ≤ Re ≤ 100. Influence of ultrasound and heat on mixing is more significant at 5 ≤ Re ≤ 20 due to the prolonged mechanical effects. It can be observed that mixing index increases by about 6% to 10% once the temperature of the sonicated fluids increases from 30 °C to 60 °C. The proposed method is potentially useful as direct contact of the inductive energy sources may cause unwanted substrate damage and structural deformation especially for applications in biological analysis and chemical synthesis.
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Chen, Zhong, Yalin Wang, and Song Zhou. "Numerical Analysis of Mixing Performance in an Electroosmotic Micromixer with Cosine Channel Walls." Micromachines 13, no. 11 (November 9, 2022): 1933. http://dx.doi.org/10.3390/mi13111933.

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Micromixers have significant potential in the field of chemical synthesis and biological pharmaceuticals, etc. In this study, the design and numerical simulations of a passive micromixer and a novel active electroosmotic micromixer by assembling electrode pairs were both presented with a cosine channel wall. The finite element method (FEM) coupled with Multiphysics modeling was used. To propose an efficient micromixer structure, firstly, different geometrical parameters such as amplitude-to-wavelength ratio (a/c) and mixing units (N) in the steady state without an electric field were investigated. This paper aims to seek a high-quality mixing solution. Therefore, based on the optimization of the above parameters of the passive micromixer, a new type of electroosmotic micromixer with an AC electric field was proposed. The results show that the vortices generated by electroosmosis can effectively induce fluid mixing. The effects of key parameters such as the Reynolds number, the number of electrode pairs, phase shift, voltage, and electrode frequency on the mixing performance were specifically discussed through numerical analysis. The mixing efficiency of the electroosmotic micromixer is quantitatively analyzed, which can be achieved at 96%. The proposed micromixer has a simple structure that can obtain a fast response and high mixing index.
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Raza, Wasim, Shakhawat Hossain, and Kwang-Yong Kim. "A Review of Passive Micromixers with a Comparative Analysis." Micromachines 11, no. 5 (April 27, 2020): 455. http://dx.doi.org/10.3390/mi11050455.

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A wide range of existing passive micromixers are reviewed, and quantitative analyses of ten typical passive micromixers were performed to compare their mixing indices, pressure drops, and mixing costs under the same axial length and flow conditions across a wide Reynolds number range of 0.01–120. The tested micromixers were selected from five types of micromixer designs. The analyses of flow and mixing were performed using continuity, Navier-Stokes and convection-diffusion equations. The results of the comparative analysis were presented for three different Reynolds number ranges: low-Re (Re ≤ 1), intermediate-Re (1 < Re ≤ 40), and high-Re (Re > 40) ranges, where the mixing mechanisms are different. The results show a two-dimensional micromixer of Tesla structure is recommended in the intermediate- and high-Re ranges, while two three-dimensional micromixers with two layers are recommended in the low-Re range due to their excellent mixing performance.
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da Cunha, Marcio Rodrigues, Antonio Carlos Seabra, and Mário R. Gongora-Rubio. "LTCC 3D MICROMIXER OPTIMIZATION FOR PROCESS INTENSIFICATION." Additional Conferences (Device Packaging, HiTEC, HiTEN, and CICMT) 2012, CICMT (September 1, 2012): 000563–72. http://dx.doi.org/10.4071/cicmt-2012-tha13.

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Mixing of fluids is a very important unit operation for Chemical, Biochemical, & Pharmaceutical processes among others, with a great deal of interest for industrial and research sectors. Micromixers a new implementation in micro scale of mixers are being studied. Active (electrokinetic, pressure disturbances, ultrasonic, magneto-hydrodynamic) and passive (jet breakup, vortex, microchannels ) methods appear in the literature. In particular research of micromixers with microchannels having different kind of elbows are conducted focusing hydrodynamic phenomena in microscale, like caotic advection. LTCC Microsystem Technology is suitable for the construction of micromixers because their inherent capacity of implementing 2D and 3D structures. The goal of the present work is to report our current study on LTCC micromixers based on microchannels having different kind of elbows for geometry optimization applying finite element Computational Fluid Dynamic numerical methods for process chemical intensification. The study will contemplate nine different 2D and 3D LTCC micromixer geometries compared with straight channel micromixer and prospect hydrodynamic parameters as: flow rate, pressure difference, friction factor and head loss coefficient. It is also presented a description of flowage as a function of diffusion-convection equation in order to obtain the mixing performance of designed devices.
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Dissertations / Theses on the topic "Micromixer"

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Ferrante, Francesco. "Antisolvent Precipitation of L-Asparagine in a Commercial Micromixer." Thesis, KTH, Skolan för kemivetenskap (CHE), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-146310.

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A commercial valve-assisted micromixer, manufactured by Ehrfeld (Germany), was tested for its use to precipitate L-asparagine from an aqueous solution using isopropanol as antisolvent. In a first part the mixing quality provided by the micromixer was studied by means of a competitive/parallel set of reactions following the approach of Baldyga, Bourne and Walker, Canadian J. Chem. Eng. 76 (1998) 641-649. Different experiments have been implemented and interpreted considering the average of Reynolds number of the inlet streams. Results show a good mixing quality that is comparable, in terms of absolute values of conversion, with other works present in literature. The precipitation experiments that followed revealed the limitation of the micromixer. The system was instable and particles adhesion occurred inside the mixing chamber. Improvements have been realized by changing the spring tension of the valve and introducing a commercial surfactant TRITON X-100.
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Wang, Hengzi, and na. "Passive mixing in microchannels with geometric variations." Swinburne University of Technology, 2004. http://adt.lib.swin.edu.au./public/adt-VSWT20061013.162737.

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This research project was part of the microfluidic program in the CRC for Microtechnology, Australia, during 2000 to 2003. The aim of this research was to investigate the feasibility of applying geometric variations in a microchannel to create effects other than pure molecular diffusion to enhance microfluidic mixing. Geometric variations included the shape of a microchannel, as well as the various obstacle structures inside the microchannel. Generally, before performing chemical or biological analysis, samples and reagents need to be mixed together thoroughly. This is particularly important in miniaturized Total Analysis Systems (�TAS), where mixing is critical for the detection stage. In scaling down dimensions of micro-devices, diffusion becomes an efficient method for achieving homogenous solutions when the characteristic length of the channels becomes sufficiently small. In the case of pressure driven flow, it is necessary to use wider microchannels to ensure fluids can be pumped through the channels and the volume of fluid can provide sufficient signal intensity for detection. However, a relatively wide microchannel makes mixing by virtue of pure molecular diffusion a very slow process in a confined volume of a microfluidic device. Therefore, mixing is a challenge and improved methods need to be found for microfluidic applications. In this research, passive mixing using geometric variations in microchannels was studied due to its advantages over active mixing in terms of simplicity and ease of fabrication. Because of the nature of laminar flow in a microchannel, the geometric variations were designed to improve lateral convection to increase cross-stream diffusion. Previous research using this approach was limited, and a detailed research program using computational fluid dynamic (CFD) solvers, various shapes, sizes and layouts of geometric structures was undertaken for the first time. Experimental measurements, published experimental data and analytical predictions were used to validate the simulations for selected samples. Mixing efficiency was evaluated by using mass fraction distributions. It was found that the overall performance of a micromixer should include the pressure drop in a microdevice, therefore, a mixing index criterion was formulated in this research to combine the effect of mixing efficiency and pressure drop. The mixing index was used to determine optimum parameters for enhanced mixing, as well as establish design guidelines for such devices. Three types of geometric variations were researched. First, partitioning in channels was used to divide fluids into mixing zones with different concentrations. Various designs were investigated, and while these provided many potential solutions to achieving good mixing, they were difficult to fabricate. Secondly, structures were used to create lateral convection, or secondary flows. Most of the work in this category used obstacles to disrupt the flow. It was found that symmetric layouts of obstacles in a channel had little effect on mixing, whereas, asymmetric arrangements created lateral convection to enhance crossstream diffusion and increase mixing. Finally, structures that could create complex 3D advections were investigated. At high Reynolds numbers (Re = 50), 3D ramping or obstacles generated strong lateral convection. Microchannels with 3D slanted grooves were also investigated. Mixers with grooved surfaces generated helicity at low Reynolds numbers (Re � 5) and provided a promising way to reduce the diffusion path in microchannels by stretching and folding of fluid streams. Deeper grooves resulted in better mixing efficiency. The 3D helical advection created by the patterned grooves in a microchannel was studied by using particle tracing algorithms developed in this research to generate streaklines and Poincare maps, which were used to evaluate the mixing performance. The results illustrated that all the types of mixers could provide solutions to microfluidic mixing when dimensional parameters were optimized.
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Farangis, Zadeh Hamid. "Experimental validation of flow and mass transport in an electrically excited micromixer." Karlsruhe : FZKA, 2005. http://bibliothek.fzk.de/zb/berichte/FZKA7152.pdf.

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Bessoth, Fiona Gabriele. "Microstructure for efficient continuous flow mixing." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367869.

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HONG, CHIEN-CHONG. "ON-CHIP PASSIVE FLUIDIC MICROMIXER AND PRESSURE GENERATOR FOR DISPOSABLE LAB-ON-A-CHIPS." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1100898243.

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Hong, Chien-Chong. "On-chip passive fluidic micromixer and pressure generator for disposable Lab-on-a Chips." Cincinnati, Ohio : University of Cincinnati, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=ucin1100898243.

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Asano, Shusaku. "Rational Design of Micromixers and Reaction Control in Microreactors." Kyoto University, 2018. http://hdl.handle.net/2433/232008.

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Lilly, David Ryan. "VIABILITY OF A CONTROLLABLE CHAOTIC MICROMIXER THROUGH THE USE OF TITANIUM-NICKEL SHAPE MEMORY ALLOY." UKnowledge, 2011. http://uknowledge.uky.edu/me_etds/1.

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Microfluidic devices have found applications in a number of areas, such as medical analysis, chemical synthesis, biological study, and drug delivery. Because of the small channel dimensions used in these systems, most microchannels exhibit laminar flow due to their low Reynold’s number, making mixing of fluids very challenging. Mixing at this size scale is diffusion-limited, so inducing chaotic flow patterns can increase the interface surface area between two fluids, thereby decreasing overall mixing time. One method to create a chaotic flow within the channel is through the introduction of internal protrusions into the channel. In such an application protrusions that create a rotational flow within the channel are preferred due to their effectiveness in folding the two fluids over one another. The novel mixer outlined in this paper uses a Ti-Ni shape memory alloy for the creation of protrusions that can be turned controlled through material temperature. Controllability of the alloy allows users to turn the chaotic flow created by the protrusions off and on by varying the temperature of the mixer. This ability contributes to the idea of a continuous microfluidic system that can be turned on only when necessary as well as recycle unmixed fluids while turned off.
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Reynol, Alvaro. "Modelagem e simulação de micromisturadores." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/3/3137/tde-24092008-141009/.

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A microfluídica juntamente com a intensificação de processos são duas áreas de pesquisa interessadas no estudo e desenvolvimento de processos em escala micrométrica capazes de manipular diminutas quantidades de reagentes. Para tanto, estes devem contar com dispositivos de pequena escala de tamanho e ao mesmo tempo serem tão confiáveis e eficientes quanto os de escala industrial. Uma das operações unitárias envolvidas nesses processos é a agitação. Em função da ordem de grandeza dos equipamentos e dos materiais em que são fabricados, grandes diferenciais de pressão não podem ser aplicados nos mesmos e como conseqüência no interior dos micromisturadores, como são conhecidos tais equipamentos, o escoamento se dá em regime laminar, sob está condição o processo de mistura é controlado pela difusão entre os componentes. Uma maneira de superar esta dificuldade é gerar no interior do micromisturador o aparecimento de um escoamento caótico. Para tal, podem-se utilizar fontes de energia externa (micromisturadores ativos) ou a própria energia do escoamento (micromisturadores passivos) através da construção de geometrias especiais. O desenvolvimento em laboratório destes equipamentos demanda tempo e geralmente é oneroso. A principal alternativa para este trabalho é a dinâmica dos fluidos computacional (CFD), ferramenta aplicada no presente estudo para analisar três geometrias diferentes propostas e analisadas experimentalmente no trabalho de Cunha (2007). Para caracterizar o funcionamento dos mesmos foram testadas quatro vazões distintas, com as quais foi possível levantar os perfis de pressão, velocidade e fração mássica de dois componentes que eram misturados. Com o intuito de demonstrar a eficiência dos equipamentos dois parâmetros foram analisados: o avanço da qualidade da mistura e a perda de carga para as diferentes condições operacionais. Apesar da limitação da malha e de não ter-se obtido resultados independentes da malha, foi possível se fazer uma comparação entre as três geometrias e identificouse que os micromisturadores M2 e M3 são os que apresentam o melhor desempenho para a faixa de vazão simulada (120 < Re < 1200).
Microfluidics and process intensification are two research areas interested in the study and development of new micrometric-scale devices capable of manipulating and processing small quantities of reagents. These processes have to deal with small scale equipment and at the same time be as reliable and efficient as the large-scale one. Because of the scale of this equipment and the material it is made of, large pressure differential is not possible, as a consequence in the interior of the micromixers, as they are known; a laminar flow develops, under those circumstances the mixing process is controlled by the diffusion mechanism between the two components. One way to suppress this deficiency is to generate a chaotic flow on the micromixer, which can be done by using external energy (active micromixer) or its own flow energy (passive micromixer) through special geometry construction. The experimental development of such microdevices demands time and, generally, is very expensive. The main alternative for this activity is the use of computational fluid dynamics; this tool was employed on this work with the aim of studying three geometries proposed by Cunha (2007). To characterize their working process, four different volumetric flows were simulated and analyzed the pressure, velocity and mass fraction profiles. Two parameters were calculated in order to characterize their efficiency: the mixture quality along the micromixers cross sections and the pressure drop for different operational conditions. Although we have mesh size limitations and a mesh independent results were not obtained it was possible to compare the three micromixers geometries and it was found out that both M2 and M3 micromixers had the best performance under operational conditions tested (120 < Re < 1200).
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Loy, Dominik [Verfasser], and Ernst [Akademischer Betreuer] Wagner. "Development of an automated micromixer for the controlled formulation of multi-component polyplexes / Dominik Loy ; Betreuer: Ernst Wagner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2021. http://d-nb.info/1232176273/34.

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Books on the topic "Micromixer"

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Nguyen, Nam-Trung. Micromixers: Fundamentals, design, and fabrication. 2nd ed. Amsterdam: Elsevier/William Andrew, 2012.

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Nguyen, Nam-Trung. Micromixers: Fundamentals, design and fabrication. Norwich, NY: William Andrew, 2008.

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Nguyen, Nam-Trung. Micromixers: Fundamentals, design and fabrication. Norwich, NY: William Andrew, 2008.

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Afzal, Arshad, and Kwang-Yong Kim. Analysis and Design Optimization of Micromixers. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4291-0.

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Micromixers. Elsevier, 2012. http://dx.doi.org/10.1016/c2011-0-69734-0.

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Passive Micromixers. MDPI, 2018. http://dx.doi.org/10.3390/books978-3-03897-008-8.

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Nguyen, Nam-Trung. Micromixers: Fundamentals, Design and Fabrication. Elsevier Science & Technology Books, 2011.

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Analysis, Design and Fabrication of Micromixers. MDPI, 2021. http://dx.doi.org/10.3390/books978-3-0365-1367-6.

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Afzal, Arshad, and Kwang-Yong Kim. Analysis and Design Optimization of Micromixers. Springer Singapore Pte. Limited, 2020.

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Kim, Kwang-Yong, ed. Analysis, Design and Fabrication of Micromixers, Volume II. MDPI, 2023. http://dx.doi.org/10.3390/books978-3-0365-6173-8.

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Book chapters on the topic "Micromixer"

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Kim, Dong Sung, Seok Woo Lee, Tai Hun Kwon, and Seung S. Lee. "Barrier Embedded Chaotic Micromixer." In Micro Total Analysis Systems 2002, 757–59. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-010-0504-3_52.

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Choi, Jin-Woo, Chien-Chong Hong, and Chong H. Ahn. "An Electrokinetic Active Micromixer." In Micro Total Analysis Systems 2001, 621–22. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-1015-3_273.

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Woias, Peter, Karin Hauser, and Erwin Yacoub-George. "An Active Silicon Micromixer for μTAS Applications." In Micro Total Analysis Systems 2000, 277–82. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-2264-3_63.

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Javed, Syed Farhan, Mohammad Zunaid, and Mubashshir Ahmad Ansari. "Mathematical Analysis of a Spiral Passive Micromixer." In Lecture Notes in Mechanical Engineering, 805–12. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-9678-0_67.

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Pfeifer, T., and Ubaldo Aleriano. "Micromixer Module With an Integrated Optical Pressure Gauge." In MicroNano Integration, 67–76. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18727-8_8.

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Liu, Robin H., Michael Ward, Justin Bonanno, Dale Ganser, Mahesh Athavale, and Piotr Grodzinski. "Plastic In-Line Chaotic Micromixer for Biological Applications." In Micro Total Analysis Systems 2001, 163–64. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-1015-3_69.

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Nafea, Marwan, Nasarudin Ahmad, Ahmad Ridhwan Wahap, and Mohamed Sultan Mohamed Ali. "Modeling and Simulation of a Wireless Passive Thermopneumatic Micromixer." In Communications in Computer and Information Science, 312–22. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-6463-0_27.

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Wu, Yue, Shenggao Li, Mohammed Ismail, and Håkan Olsson. "A Low Power CMOS Micromixer for GHz Wireless Applications." In VLSI: Systems on a Chip, 35–46. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-0-387-35498-9_4.

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Hong, Chien-Chong, Jin-Woo Choi, and Chong H. Ahn. "A Novel In-Plane Passive Micromixer Using Coanda Effect." In Micro Total Analysis Systems 2001, 31–33. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-1015-3_11.

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Ali, Md Ashraf, and Lyazid Djenidi. "Lattice Boltzmann Simulation of Pulsed Jet in T-Shaped Micromixer." In IUTAM Symposium on Advances in Micro- and Nanofluidics, 167–74. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2626-2_13.

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Conference papers on the topic "Micromixer"

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Jiang, Yuan, and Yan Zhang. "High performance micromixers by 3D printing based on split-and-recombine modules and twisted-architecture microchannel." In Intelligent Human Systems Integration (IHSI 2022) Integrating People and Intelligent Systems. AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001085.

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Micromixers present essential roles in providing homogeneous mixtures in microfluidic systems. As the typical passive micromixers, the split-and-recombine (SAR) micromixer and twisted-architecture micromixer have the advantages of high mixing efficiency and low mixing consumption.To enhance the mixing performance , the twisted-architecture micromixer was optimized and improved by introducing 1 to 4 split-and-recombine modules. All micromixers in this work could be fabricated by LCD 3D printers, a rapid prototyping technology. Combined with mixing experiments and numerical simulation, it is proved that the mixing speed and mixing efficiency of these new micromixers are enhanced greatly. Among these new provided micromixers with a 10 mm mixing distance, the torsional micromixer with 4 split-and-recombine modules has the best mixing efficiency of more than 60% as well as a low mixing cost in the Reynolds number range of 0.1 to 100, which shows a quite good application prospects in the accurate and rapid microfluidic devices.
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Nakahara, Tasuku, Norifumi Ootani, Toshiyuki Asanuma, Yoshinori Hagio, Daisuke Hiramaru, Kyohei Terao, Atsuhito Okonogi, Fumikazu Oohira, Hidetoshi Kotera, and Takaaki Suzuki. "Development of a Three Dimensional Passive Lamination Micromixer." In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajk2011-36025.

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In this paper, we propose a three-dimentional multi-layered flow generator fabricated by inclined UV lithography to expose a single layerded photoresist coated on a patterned mask. To confirm the validity of the proposed generator, we applied the three-layered flow generator as a passive lamination micromixer. By comparing two types of fabricated micromixers, the three-layered micromixer achieves 1.64 times faster mixing rate than a conventional Y-shaped one due to the shortening of the diffusion length. The fabricated flow generator can be applied for a passive micromixer with laminated and/or secondary flows, a sheath flow generator, and a multi-layered emulsion system.
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Husain, Afzal, Farhan A. Khan, Nabeel Z. Al-Rawahi, and Abdus Samad. "Blood Flow and Mixing Analysis in Split-and-Recombine Micromixer With Offset Fluid Inlets." In ASME 2018 5th Joint US-European Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/fedsm2018-83468.

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In this study, a variant of 3D split-and-recombine micromixer is proposed for enhanced micromixing. The mixing analysis was carried out for water and blood flows through the three-dimensional numerical model. The blood flow was modeled using several non-Newtonian fluid models existed in the literature and performance was compared for mixing index. Further, the performance of the proposed micromixer was compared with several other designs of micromixers available in the open literature for a wide range of Reynolds numbers covering diffusion, transient, and advection-dominated flow regimes. Finally, Carreau-Yasuda model was used to carry out parametric analysis of the proposed micromixer for mixing index.
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Farshchian, Bahador, Junseo Choi, and Sunggook Park. "3D Micromixer." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-88031.

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This paper presents the fabrication of a 3D microchannel whose sidewalls and bottom surface are patterned with ratchets using a modified 3D molding process. In the modified 3D molding process the surface of poly(methyl methacrylate) (PMMA) is first patterned using a brass mold having ratchet structures. Then PDMS prepolymer was spin coated over the surface of micropatterned PMMA and cured followed by the primary molding using a brass mold having a T-conjunction protrusion. After primary molding demolding was done by first demolding the brass mold and then peeling off PDMS stamp from PMMA substrate. By setting a 45° angle between direction of ratchets patterned on the surface of PMMA and the brass mold protrusion prior to primary molding 45° slanted ratchets were formed on the sidewall and bottom surface of microchannel using the modified 3D molding. The scanning electron microscope (SEM) micrographs show a successful integration of micropatterns inside the microchannel. Holes were drilled in the inlet and outlet area of the 3D channel before bonding. A solvent bonding technique was used for bonding of 3D channel to a plain cover plate. After bonding capillary tubes were inserted into the holes and glued to the chip using an epoxy glue. For characterization of mixing fluorescence intensity was quantified in the 3D microchannel as deionized water and fluorescein dye injected from different inlets of 3D micromixer were mixed along the 3D microchannel and mixing efficiency was calculated. The results were compared with the data obtained for similar microdevice whose surfaces were not patterned. The results demonstrate at a specific flow rate a faster mixing occurs in a microdevice whose sidewall and bottom surface are patterned with slanted 45° ratchets.
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Fan, YanFeng, and Ibrahim Hassan. "The Numerical Simulation of a Passive Interdigital Micromixer With Uneven Lamellar Width." In ASME 2009 7th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2009. http://dx.doi.org/10.1115/icnmm2009-82076.

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In this paper, a passive micromixer with interdigital structure is proposed and investigated using numerical simulations. The micromixer contains three layers to achieve the interdigital flow structure. The height of mixing channels is fixed as 0.2 mm. The total width of inlets is 0.9 mm. The mixing regime is rectangular in shape. The Reynolds number, measured at the entrance of straight channel, ranges from 5 to 60. Grid independence is performed to minimize the influence of numerical diffusion on simulation results. The grid size is selected as 6 μm, which can be considered as optimal. The interdigital micromixers with straight downstream channels are designed and simulated. In order to achieve better mixing near the inner walls, uneven lamellae width of each species is applied to create a larger concentration gradient near the inner walls. The results show that the micromixer with uneven lamellar width is able to enhance the mixing near the inner walls. A new passive micromixer with the uneven interdigital inlets is also designed to improve the mixing efficiency at high Re. The simulation results show that this new micromixer has a mixing efficiency larger than 80%, and a maximum pressure drop of 2.7 KPa.
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Gillispie, Aric M., and Evan C. Lemley. "Correlation of Mixing Efficiency and Entropy Generation Rate in a Square Cross Section Tee Junction Micromixer." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-72288.

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The potential applications of micromixers continues to expand in the bio-sciences area. In particular, passive micromixers that may be used as part of point-of-care (POC) diagnostic testing devices are becoming commonplace and have application in developed, developing, and relatively undeveloped locales. Characterizing and improving mixing efficiency in these devices is an ongoing research effort. Micromixers are used in some lab-on-chip (LOC) devices where it is often necessary to combine two or more fluids into a mixed solution for testing or delivery. The simplest micromixer incorporates a tee junction to combine two fluid species in anti-parallel branches, with the mixed fluid leaving in a branch perpendicular to the incoming branches. Micromixers rely on two modes of mixing: chaotic advection and molecular diffusion. In micro-mixers flow is typically laminar, making chaotic advection occur only via induced secondary flows. Hence, micromixers, unless carefully designed, rely almost exclusively on molecular diffusion of fluid species. A well designed micromixer should exhibit significant chaotic advection; which is also a sign of large strain rates and large entropy generation rates. This paper describes the development of an analytical relationship for the entropy generation rate and the mixing efficiency as function of the outgoing branch Reynolds number. Though there has been extensive research on tee junctions, entropy generation, and the mixing efficiencies of a wide variety of micromixers, a functional relationship for the mixing efficiency and the entropy generation rate has not been established. We hypothesize a positive correlation between the mixing index and the entropy generation rate. The worked described here establishes a method and provides the results for such a relationship. A basic tee junction with square cross sections has been analyzed using computational fluid dynamics to determine the entropy generation rate and outgoing mixing efficiencies for Reynolds numbers ranging from 25–75. The mixing efficiency is determined at a location in the outgoing branch where the effects of molecular diffusive mixing is minimized and chaotic advective mixing is the focus. The entropy generation rate has been determined for the indicated range of Reynolds number and decomposed into its viscous and diffusive entropy terms. The functional relationships that have been developed are applicable for micromixer design and serve as a reference for more complex passive micromixer designs.
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Kim, Hak-Sun, Hyun-Oh Kim, and Youn-Jea Kim. "Effect of Electrode Configurations on the Performance of Electro-Hydrodynamic Micromixer." In ASME 2018 16th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/icnmm2018-7654.

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Micromixers are widely used in chemical engineering and bioengineering industries. In this study, geometrical effects of electrodes were investigated to mix fine particles affected by external electric field. In order to improve the particle mixing performance of micromixer, the electroosmosis effect could be utilized with configuration of electrodes at the top and bottom of microchannel. Numerical analysis was performed to derive the pattern of electrodes with superior mixing efficiency by changing voltages and zeta potentials applied to the micromixer channel, by using COMSOL Multiphysics 5.2. The results of mixing performance were graphically depicted with various arrangements of electrode and flow conditions.
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Gosavi, Suresh, Aniket Tekawade, Dhananjay Bodas, Sukratu Barve, Laurent Robert, and Chantal Khan-Malek. "Development and Analytical Treatment of 3-D Passive Mixromixer for Enhanced Microfluidics Reactions." In ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2011. http://dx.doi.org/10.1115/icnmm2011-58263.

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With fast development of microfluidic systems, micro-mixing becomes a very important issue. Various attempts have been made to develop passive and active micromixers, wherein the mixing efficiency is mainly dependent on the diffusion coefficient and diffusion mechanism. This paper reports modeling and fabrication of a 3D micromixer based on the principle of sequential lamination for efficient mixing. Simulation of the square tube geometry with varying inlet velocity was performed. The improvement in the mixing efficiency is attributed to the increase in the contact surface between the different fluids decreasing the diffusion path in order to improve the molecular diffusion. The design approach in the present case is also supported by analytical treatment which indicates superiority of 2D transverse flows while designing a micromixer. The optimized parameters from CFD simulation were used for fabrication of the micromixer by standard photolithographic and soft lithographic techniques.
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Rubby, Md Fazlay, Mohammad Salman Parvez, and Nazmul Islam. "Simple, Cost-Effective Fabrication, and Flow Dynamics Analysis of a Passive Microfluidic Mixer Using 3D Printing and Soft Lithography." In ASME 2021 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/fedsm2021-65572.

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Abstract Simple and low-cost fabrication of microfluidic devices has attracted considerable attention among researchers. The traditional soft lithography fabrication method requires expensive equipment like a UV exposure system and mask fabrication facility. In this work, an alternative and low-cost UV exposure system was introduced along with an alternative mask fabrication system. A previously reported passive microfluidic mixer was fabricated successfully using this modified soft lithography method. Challenges were presented during this modified fabrication method. Another emerging potential alternative for the fabrication of microfluidic mixers is 3D printing. It was also used in this experiment to fabricate a passive micromixer. This method is well known for rapid prototyping and the creations of complex structures. However, this method has several disadvantages like optical transparency, lower resolution fabrication, difficulties in flow characterization, etc. These problems were addressed, and the solutions were discussed in this work. Comparative analysis between 3D printing and soft lithography fabrication was presented. Flow characterization inside the 3D printed micromixer was carried out using the microparticulate image velocimetry (micro-PIV) system. It explains how the geometrical shape of the micromixer accelerates the natural diffusion process to mix the different fluid streams. Finally, a 3D numerical simulation of the passive micromixer was carried out to visualize the flow dynamics inside the micromixer. The flow pattern found from the numerical simulation and the experimental flow characterization is analogous. These observations could play an important role to design and fabricate cost-effective micromixers for lab-on-a-chip devices.
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Song, Hongjun, Xie-Zhen Yin, and Dawn J. Bennett. "The Design and Simulation for a Novel Electroosmotic Micromixer." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-16092.

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The analysis of fluid mixing in microfluidic systems is useful for many biological and chemical applications at the micro scale such as the separation of biological cells, chemical reactions, and drug delivery. The mixing of fluids is a very important factor in chemical reactions and often determines the reaction velocity. However, the mixing of fluids in microfluidics tends to be very slow, and thus the need to improve the mixing effect is a critical challenge for the development of the microfluidic systems. Micromixers can be classified into two types, active micromixers and passive micromixers. Passive micromixers depend on changing the structure and shape of microchannels in order to generate chaotic advection and to increase the mixing area. Thus, the mixing effect is enhanced without any help from external forces. Although passive micromixers have the advantage of being easily fabricated and requiring no external energy, there are also some disadvantages. For example, passive mixers often lack flexibility and power. Passive mixers rely on the geometrical properties of the channel shapes to induce complicated fluid particle trajectories thereby enhancing the mixing effect. On the other hand, active micromixers induce a time-dependent perturbation in the fluid flow. Active micromixers mainly use external forces for mixing including ultrasonic vibration, dielectrophoresis, magnetic force, electrohydrodynamic, and electroosmosis force. However, the complexity of their fabrication limits the application of active micromixers. In this paper we present a novel electroosmotic micromixer using the electroosmotic flow in the cross section to enhance the mixing effect. A DC electric field is applied to a pair of electrodes which are placed at the bottom of the channel. A transverse flow is generated in the cross section due to electroosmotic flow. Numerical simulations are investigated using a commercial software Fluent® which demonstrates how the device enhances the mixing effect. The mixing effect is increased when the magnitude of the electric field increased. The influences of Pe´clet number are also discussed. Finally, a simple fabrication using polymeric materials such as SU-8 and PDMS is presented.
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Reports on the topic "Micromixer"

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Webb, Stephen W., Darryl L. James, Michael R. Hibbs, Howland D. T. Jones, William Eugene Hart, Siri Sahib Khalsa, Susan Jeanne Altman, et al. Analysis of micromixers and biocidal coatings on water-treatment membranes to minimize biofouling. Office of Scientific and Technical Information (OSTI), December 2009. http://dx.doi.org/10.2172/972867.

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