Academic literature on the topic 'Microenviroment Lymphoma Primary Testicular Diffuse Large B-cell Lymphoma'

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Journal articles on the topic "Microenviroment Lymphoma Primary Testicular Diffuse Large B-cell Lymphoma"

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Wang, Qi, Dafang Zheng, Damin Chai, Shiwu Wu, Xiaolin Wang, Shaonan Chen, Linhui Wu, Ruoxue Cao, and Yisheng Tao. "Primary testicular diffuse large B-cell lymphoma." Medicine 99, no. 12 (March 2020): e19463. http://dx.doi.org/10.1097/md.0000000000019463.

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Trama, Francesco, Ester Illiano, Achille Aveta, Savio Domenico Pandolfo, Giancarlo Bertuzzi, and Elisabetta Costantini. "Bilateral Primary testicular diffuse large B-CELL lymphoma." Urology Case Reports 38 (September 2021): 101733. http://dx.doi.org/10.1016/j.eucr.2021.101733.

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Drideb, Alami, and Bouchnafat Saddi. "Primary testicular diffuse large B-cell lymphoma in young patient: an uncommon presentation." Hematology & Transfusion International Journal 10, no. 4 (December 13, 2022): 104–5. http://dx.doi.org/10.15406/htij.2022.10.00290.

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Primary testicular lymphoma (PTL) is a rare form of extranodal lymphoma, this neoplasm is the most common malignant tumor of the testis in the elderly age, and the majority of cases are histologically diffuse large B-cell lymphoma (DLBCL), accounting for 80% to 98% of non-hodgkin lymphoma. Patients with primary testicular DLBCL show a continuously high risk of recurrence with no plateau in the survival curves and a tendency to involve other extranodal sites, especially the central nervous system and the contralateral testis. We report a rare and uncommon presentation of a primary testicular diffuse B cell lymphoma in young patient.
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Knežević, Snežana, Bojana Trikoš, and Ivan Gajović. "Primary testicular diffuse large B-cell lymphoma, presented as phlebothrombosis." Timocki medicinski glasnik 43, no. 2 (2018): 72–76. http://dx.doi.org/10.5937/tmg1802072k.

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Sadiq, Muhammad, Iftikhar Ahmad, Jamila Shuja, Zia Ullah Khan, and Khushnaseeb Ahmad. "Primary testicular diffuse large B-cell lymphoma: A case report." Egyptian Journal of Basic and Applied Sciences 4, no. 4 (December 2017): 358–60. http://dx.doi.org/10.1016/j.ejbas.2017.10.007.

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Horne, Matthew J., and Adebowale J. Adeniran. "Primary Diffuse Large B-Cell Lymphoma of the Testis." Archives of Pathology & Laboratory Medicine 135, no. 10 (October 1, 2011): 1363–67. http://dx.doi.org/10.5858/arpa.2010-0158-rs.

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In this short review, we discuss primary diffuse large B-cell lymphoma of the testis, an entity that is most commonly seen in older patients. The most common clinical presentation is a unilateral testicular mass. Microscopically, the tumor shows diffuse infiltration of lymphocytes between intact seminiferous tubules. Spermatogenic arrest, interstitial fibrosis, and tubular hyalinization are commonly seen. The tumor is positive for B-cell markers by immunohistochemistry. Treatment has traditionally been with orchiectomy and combination chemotherapy; however, only a minority of patients enjoy a prolonged disease-free survival. Differential diagnosis includes seminoma and viral and granulomatous orchitis.
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Cheah, Chan Y., Andrew Wirth, and John F. Seymour. "Primary testicular lymphoma." Blood 123, no. 4 (January 23, 2014): 486–93. http://dx.doi.org/10.1182/blood-2013-10-530659.

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Abstract Primary testicular lymphoma (PTL) is a rare, clinically aggressive form of extranodal lymphoma. The vast majority of cases are histologically diffuse large B-cell lymphoma, but rarer subtypes are clinically important and must be recognized. In this review, we discuss the incidence, clinical presentation, and prognostic factors of PTL and present a summary of the recent advances in our understanding of its pathophysiology, which may account for the characteristic clinical features. Although outcomes for patients with PTL have historically been poor, significant gains have been made with the successive addition of radiotherapy (RT), full-course anthracycline-based chemotherapy, rituximab and central nervous system–directed prophylaxis. We describe the larger retrospective series and prospective clinical trials and critically examine the role of RT. Although rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone given every 21 days with intrathecal methotrexate and locoregional RT is the current international standard of care, a substantial minority of patients progress, representing an unmet medical need. Finally, we discuss new treatment approaches and recent discoveries that may translate into improved outcomes for patients with PTL.
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Hussein, Abdallah, Hachem Farouk, Bellouki Omar, Ibrahimi Ahmed, Al Sayegh Hachem, and Nouini Yassine. "Primary Testicular Diffuse Large B-cell Lymphoma Presenting in a Young Adult." Saudi Journal of Medicine 7, no. 6 (June 15, 2022): 342–45. http://dx.doi.org/10.36348/sjm.2022.v07i06.002.

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Primary testicular lymphoma is a rare type of extranodal non-Hodgkin lymphoma (NHL), its positive diagnosis is based on histopathological findings. Treatment modalities consist of surgical excision, chemotherapy, and radiation therapy but the accurate procedures are not standardized. The authors report a new case of primary testicular lymphoma, and we discuss its diagnostic and therapeutic aspects. Sperm cryopreservation was carried out. The patient was started on chemotherapy with cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisone (CHOP) regime.
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Horsanalı, Mustafa Ozan, Gürol Akan, and Saniye Sevim Tuncer. "Primary Testicular Diffuse Large B-cell Lymphoma: A Rare Case Report." Journal of Urological Surgery 8, no. 3 (September 1, 2021): 220–22. http://dx.doi.org/10.4274/jus.galenos.2021.2021.0009.

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Tsili, A. C., M. I. Argyropoulou, D. Giannakis, N. Sofikitis, and K. Tsampoulas. "Primary diffuse large B-cell testicular lymphoma: magnetic resonance imaging findings." Andrologia 44 (October 11, 2011): 845–47. http://dx.doi.org/10.1111/j.1439-0272.2011.01236.x.

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Dissertations / Theses on the topic "Microenviroment Lymphoma Primary Testicular Diffuse Large B-cell Lymphoma"

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Virginia, Mancini. "The Lymphoma Microenviroment." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1194259.

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The study of the microenviroment, the cellular milieau in wich the neoplastic cells thrive, represents a relevant focus of investigation in order to explore potential targets for immunotherapy. Using immunohistochemistry tecnique, we analyzed the lymphoma microenviroment in particular in sampling of Primary Testicular Diffuse Large B-cells Lymphoma, an aggressive lymphoma for wich few therapeutic strategies are available.
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Book chapters on the topic "Microenviroment Lymphoma Primary Testicular Diffuse Large B-cell Lymphoma"

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Artiles Medina, Alberto, Javier Lorca Álvaro, Inés Laso García, César Mínguez Ojeda, Marina Mata Alcaraz, Marta Santiago González, Mariam Bajawi Carretero, Juan José Gordillo Perdomo, Victoria Gómez Dos Santos, and Francisco Javier Burgos Revilla. "Testicular Lymphoma: Primary and Secondary Involvement." In Lymphoma [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101505.

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This chapter explores the testicular involvement of lymphoma. Testicular lymphoma may either represent secondary involvement by systemic disease or primary malignancy. Regarding primary testicular lymphoma (PTL), it is a rare form of extranodal lymphoma and the most frequent malignant testicular neoplasm in men over the age of 60 years. The diffuse large B-cell lymphoma (DLBCL) accounts for the majority of cases. The morphologic manifestation of PTL on imaging may be in the form of a localized mass or a diffuse enlargement of the testis. On ultrasonography, PTL usually appears as a hypoechoic area with hypervascularity. MRI and positron emission tomography with computed tomography (PET/CT) are useful diagnostic tools. The latter is crucial in staging and follow-up of these patients. The treatment of PTL is based on orchiectomy, chemotherapy, and radiotherapy. The prognosis is poor and PTL exhibits a propensity to relapse in the central nervous system (CNS) and in the opposite testis. Secondary involvement of the testis by non-Hodgkin lymphoma (NHL) is more frequent than PTL. Patients may develop the relapsed or refractory disease in the testis in the context of disseminated lymphomas due to the existence of the blood-testis barrier. This chapter discusses the treatment of secondary involvement by lymphoma.
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