Academic literature on the topic 'Methaemoglobin'

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Journal articles on the topic "Methaemoglobin"

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Godwin, I., L. Li, K. Luijben, et al. "The effects of chronic nitrate supplementation on erythrocytic methaemoglobin reduction in cattle." Animal Production Science 55, no. 5 (2015): 611. http://dx.doi.org/10.1071/an13366.

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Calcium nitrate and urea were fed as a supplement on an isonitrogenous basis to Angus steers and their erythrocytic methaemoglobin concentrations and NADH- and NADPH-methaemoglobin reductase levels were measured over a 54-day period. Methaemoglobin concentrations remained elevated despite increases in NADH-methaemoglobin reductase activity. In a second experiment, Brahman cross steers were fed either calcium nitrate or urea supplements for 111 days. Blood cells were then taken, washed and exposed to sodium nitrite to convert all haemoglobin to methaemoglobin. The rates of glycolysis and methae
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Marrs, T. C., J. E. Bright, and R. H. Inns. "Methaemoglobin Production and Reduction by Methylene Blue and the Interaction of Methylene Blue with Sodium Nitrite in vivo." Human Toxicology 8, no. 5 (1989): 359–64. http://dx.doi.org/10.1177/096032718900800505.

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Methylene blue, at high concentrations, interferes with the estimation of methaemoglobin using the IL 282 CO-oximeter: the dye does not interfere with the method of Evelyn & Malloy for determination of methaemoglobin. In beagle bitches methylene blue causes both methaemoglobinogenesis and methaemoglobin reduction, the effect of the former being to delay the decline of methaemoglobin levels, when methylene blue is used to reverse the methaemoglobinaemia produced by sodium nitrite.
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Stejskalová, Jana, Pavel Stopka, and Zdeněk Pavlíček. "An ESR study of the peroxidase reaction catalyzed by human methaemoglobin and methaemoglobin-haptoglobin complex." Collection of Czechoslovak Chemical Communications 56, no. 4 (1991): 923–32. http://dx.doi.org/10.1135/cccc19910923.

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The ESR spectra of peroxidase systems of methaemoglobin-ascorbic acid-hydrogen peroxide and methaemoglobin-haptoglobin complex-ascorbic acid-hydrogen peroxide have been measured in the acetate buffer of pH 4.5. For the system with methaemoglobin an asymmetrical signal with g ~ 2 has been observed which is interpreted as the perpendicular region of anisotropic spectrum of superoxide radical. On the other hand, for the system with methaemoglobin-haptoglobin complex the observed signal with g ~ 2 is symmetrical and is interpreted as a signal of delocalized electron. After realization of three rep
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Marrs, T. C., R. H. Inns, J. E. Bright, and S. G. Wood. "The Formation of Methaemoglobin by 4-aminopropiophenone (PAPP) and 4-(N-hydroxy) aminopropiophenone." Human & Experimental Toxicology 10, no. 3 (1991): 183–88. http://dx.doi.org/10.1177/096032719101000306.

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Oral dosing of rats with the cyanide antidote 4-aminopropiophenone (PAPP), brought about peak methaemoglobin levels at 15-40 min, but peak levels were attained at 15-25 min after intravenous dosing. After both oral and intravenous administration at equimolar doses, 4-(N-hydroxy)aminopropiophenone (PHAPP), the putative methaemoglobin-producing metabolite of PAPP, produced higher peak levels of methaemoglobin than PAPP. Plasma from rats injected with PAPP was capable of forming methaemoglobin when added to naive rat erythrocytes. The identity of the metabolite responsible is discussed.
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Benu, I., M. J. Callaghan, N. Tomkins, G. Hepworth, L. A. Fitzpatrick, and A. J. Parker. "The effect of feeding frequency and dose rate of nitrate supplements on blood haemoglobin fractions in Bos indicus cattle fed Flinders grass (Iseilemia spp.) hay." Animal Production Science 56, no. 10 (2016): 1605. http://dx.doi.org/10.1071/an14886.

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Twelve Bos indicus steers (liveweight ± s.d., 317.8 ± 28.5) kg were used in an experiment to examine two factors: daily nitrate dose (0, 30, 40 or 50 g of nitrate/day) and feeding frequency (once or twice a day) on methaemoglobin concentration, daily peak methaemoglobin concentration, rate of incline for methaemoglobin concentration, carboxyhaemoglobin concentration, oxyhaemoglobin concentration, total haemoglobin concentration, haematocrit and dry matter intake of Flinders grass hay. Increasing the dose rate of nitrate increased the fraction of methaemoglobin in the blood of steers (P = 0.014
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Marrs, T. C., and J. E. Bright. "Kinetics of Methaemoglobin Production (1)." Human Toxicology 5, no. 5 (1986): 295–301. http://dx.doi.org/10.1177/096032718600500501.

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Methaemoglobin profiles have been studied by using ISIS, a simulation package, and NONLIN, a ion-linear least-squares analysis regression program. A simple kinetic model which satisfactorily describes methaemoglobin profiles after p-aminopropiophenone (PAPP) administration and 4-dimethylaminophenol (DMAP) administration has been developed. The two compounds differed nainly in their effective rates of elimination. The model less satisfactorily described methaemoglobin profiles after p-hydroxyaminopropiophenone (PHAPP) administration.
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Wells, Rufus M. G., John Baldwin, and Roger S. Seymour. "Low concentrations of methaemoglobin in marine fishes of the Great Barrier Reef, Australia." Marine and Freshwater Research 48, no. 4 (1997): 303. http://dx.doi.org/10.1071/mf97024.

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Concentrations of methaemoglobin (the oxidized non-functional ferric form of haemoglobin) in the blood of marine fish are poorly documented. Although high concentrations have been reported for fish maintained in captivity, baseline values for wild populations are unknown. Two techniques, the cyanide derivative method and the multiple wavelength method, were used to determine methaemoglobin concentrations in blood samples from 25 species of marine teleosts and elasmobranchs captured on the Australian Great Barrier Reef. Although methaemoglobin generally accounted for less than 2% of total haemo
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Lamont, A. S. M., M. S. Roberts, D. G. Holdsworth, A. Atherton, and J. J. Shepherd. "Relationship between Methaemoglobin Production and Methylene Blue Plasma Concentrations under General Anaesthesia." Anaesthesia and Intensive Care 14, no. 4 (1986): 360–64. http://dx.doi.org/10.1177/0310057x8601400406.

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Recently, a family tree with a predisposition for the gene of multiple endocrine neoplasia Type 1 has been identified in Tasmania. As the surgical identification and localisation of parathyroid adenomas is facilitated by the administration of methylene blue, an opportunity has presented to measure the plasma concentration of methylene blue and methaemoglobin production. The study was undertaken to establish whether significant methaemoglobin concentrations were generated during the infusion and whether these concentrations could be related to the corresponding methylene blue concentrations. Me
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Chikezie, P. C. "Methaemoglobin Content and NADH-methaemoglobin Reductase Activity of Three Human Erythrocyte Genotypes." Asian Journal of Biochemistry 6, no. 1 (2010): 98–103. http://dx.doi.org/10.3923/ajb.2011.98.103.

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Langlois, Cynthia J., and Edward J. Calabrese. "The Interactive Effect of Chlorine, Copper and Nitrite on Methaemoglobin Formation in Red Blood Cells of Dorset Sheep." Human & Experimental Toxicology 11, no. 3 (1992): 223–28. http://dx.doi.org/10.1177/096032719201100311.

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Simultaneous exposure to chemicals which can oxidize the haemoglobin of the red blood cell to methaemoglobin is common. Although the effects of some of these agents have been documented individually, little research considers the interactive effects. In-vitro experiments on the treated blood of female Dorset sheep assessed the interactive capacity of chlorite, copper and nitrite to affect methaemoglobin formation. All combinations of doses which produced 2.5, 5, 10% methaemoglobin were tested in all possible combinations (a total of 80), as were the controls. This included data on each chemica
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Dissertations / Theses on the topic "Methaemoglobin"

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Kennett, Eleanor. "Transmembrane Electron Transport Systems in Erythrocyte Plasma Membranes." University of Sydney. School of Molecular and Microbial Biosciences, 2005. http://hdl.handle.net/2123/620.

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Electron transport systems exist in the plasma membranes of all cells. Although not well characterised they play roles in cell growth and proliferation, hormone responses and other cell signalling events, but perhaps their most important role, especially in erythrocytes, is enabling the cell to respond to changes in both intra- and extracellular redox environments. Human erythrocytes possess a transmembrane electron transport capability that mediates the transfer of reducing equivalents from reduced intracellular species to oxidised extracellular species and is concomitant with proton extrusio
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Kennett, Eleanor. "Transmembrane Electron Transport Systems in Erythrocyte Plasma Membranes." Thesis, The University of Sydney, 2004. http://hdl.handle.net/2123/620.

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Electron transport systems exist in the plasma membranes of all cells. Although not well characterised they play roles in cell growth and proliferation, hormone responses and other cell signalling events, but perhaps their most important role, especially in erythrocytes, is enabling the cell to respond to changes in both intra- and extracellular redox environments. Human erythrocytes possess a transmembrane electron transport capability that mediates the transfer of reducing equivalents from reduced intracellular species to oxidised extracellular species and is concomitant with proton extrusio
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Book chapters on the topic "Methaemoglobin"

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Dunne, Jackie, Dimitri A. Svistunenko, Abdu I. Alayash, Michael T. Wilson, and Chris E. Cooper. "Reactions of Cross-Linked Methaemoglobins with Hydrogen Peroxide." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4717-4_2.

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Mehdi, SR. "Estimation of Methaemoglobin." In Laboratory Procedures in Haematology. Jaypee Brothers Medical Publishers (P) Ltd., 2006. http://dx.doi.org/10.5005/jp/books/10437_1.

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