Journal articles: 'Metals – Toxicology'

1

Furst, Arthur. "Toxicology of metals." International Journal of Toxicology 16, no. 6 (November 1997): 684–85. http://dx.doi.org/10.1177/109158189701600613.

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Júnior, Fernando Barbosa, Marcelo Farina, Susana Viegas, and Wilma De Grava Kempinas. "Toxicology of Metals and Metalloids." BioMed Research International 2014 (2014): 1–2. http://dx.doi.org/10.1155/2014/253738.

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3

Garriott, James C. "A Review ofHazardous Metals in Toxicology." Journal of Forensic Sciences 30, no. 3 (July 1, 1985): 11036J. http://dx.doi.org/10.1520/jfs11036j.

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4

Marchan, Rosemarie. "Highlight report: redox—metals in toxicology." Archives of Toxicology 89, no. 12 (November 28, 2015): 2475–76. http://dx.doi.org/10.1007/s00204-015-1647-x.

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Raza-Naqvi, Syed Ali, Fareeha Idrees, Tauqir A. Sherazi, Sohail Anjum-Shahzad, Sadaf Ul-Hassan, and Nimra Ashraf. "TOXICOLOGY OF HEAVY METALS USED IN COSMETICS." Journal of the Chilean Chemical Society 67, no. 3 (September 2022): 5615–22. http://dx.doi.org/10.4067/s0717-97072022000305615.

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6

Waldron, H. A. "Chemical Toxicology and Clinical Chemistry of Metals." Occupational and Environmental Medicine 42, no. 6 (June 1, 1985): 432. http://dx.doi.org/10.1136/oem.42.6.432.

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7

Forth, W. "Book Reviews : Toxicology of Metals- Biochemical Aspects." Human & Experimental Toxicology 15, no. 3 (March 1996): 277. http://dx.doi.org/10.1177/096032719601500321.

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Shi, Jianbo, and Yong Cai. "Environmental chemistry and toxicology of heavy metals." Ecotoxicology and Environmental Safety 202 (October 2020): 110926. http://dx.doi.org/10.1016/j.ecoenv.2020.110926.

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9

Meier, J. "Toxicology of metals—clinical and experimental research." Toxicon 27, no. 3 (January 1989): 400. http://dx.doi.org/10.1016/0041-0101(89)90197-9.

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10

Fry, Jeffrey R. "Book Review: Handbook of the Toxicology of Metals." Alternatives to Laboratory Animals 14, no. 3 (March 1987): 251. http://dx.doi.org/10.1177/026119298701400326.

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Munksgaard, E. C. "Toxicology Versus Allergy in Restorative Dentistry." Advances in Dental Research 6, no. 1 (September 1992): 17–21. http://dx.doi.org/10.1177/08959374920060010901.

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The frequency of side-effects among dental patients is very low and is seen mostly as mild allergic reactions. Among the dental staff, contact allergic eczema is occasionally seen, induced by certain metals and various organic materials.

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12

Slaveykova, Vera, and Giulia Cheloni. "Preface: Special Issue on Environmental Toxicology of Trace Metals." Environments 5, no. 12 (December 18, 2018): 138. http://dx.doi.org/10.3390/environments5120138.

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13

Iov, Tatiana, Mihnea Costescu, Madalina Diac, Daniel Tabian, Sofia Mihaela David, Anton Knieling, and Simona Irina Damian. "Dangerous Chemical Agents: General and Odonto-Stomatological Aspects with Importance in Forensic Toxicology." Revista de Chimie 70, no. 5 (June 15, 2019): 1829–34. http://dx.doi.org/10.37358/rc.19.5.7225.

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In the heavy and light industry, the food and pharmaceutical industry, there are chemicals that contain metals with high toxic potential. Toxicity of metals is due to the harmful effect in certain forms and doses. Some metals become toxic when they form soluble compounds or in a certain chemical structure at certain doses (eg lead, mercury and candium). Not only heavy metals are toxic metals, there are also light metals that can become toxic, some of which are essential elements (iron, selenium, copper, chromium, zinc) and metals used therapeutically in medicine (aluminum, bismuth, gold, gallium, lithium and silver) may have negative effects when administered in large quantities or the elimination from the human body is deficient. Metal poisoning occurs through nutrition, medication, environmental factors. Most professional pollutants with intraoral manifestations appear in the heavy industry. The oral cavity is an entry gate for various toxic pathogens, so intoxications can be detected early due to the manifestations inside the mouth.

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Winecker, Ruth E., Jeri D. Ropero-Miller, Larry A. Broussard, and Catherine A. Hammett-Stabler. "The Toxicology of Heavy Metals: Getting the Lead Out." Laboratory Medicine 33, no. 12 (December 2002): 934–47. http://dx.doi.org/10.1309/qnk0-wapw-1gpa-5g0j.

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15

NECHAY, BOHDAN R. "Symposium: The Role of Glutathione in Toxicology of Metals." Toxicological Sciences 5, no. 5 (1985): 805. http://dx.doi.org/10.1093/toxsci/5.5.805.

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16

Ng, Jack C., Michael R. Moore, and Xianglin Shi. "Special issue on environmental toxicology of metals and metalloids." Toxicology Letters 137, no. 1-2 (January 2003): 1. http://dx.doi.org/10.1016/s0378-4274(02)00403-4.

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17

Barbosa, Fernando. "Toxicology of metals and metalloids: Promising issues for future studies in environmental health and toxicology." Journal of Toxicology and Environmental Health, Part A 80, no. 3 (February 1, 2017): 137–44. http://dx.doi.org/10.1080/15287394.2016.1259475.

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18

SAKAI, KAZUO, and YASUHIRO YAMANE. "Cancer and metals." Eisei kagaku 36, no. 3 (1990): 181–200. http://dx.doi.org/10.1248/jhs1956.36.181.

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19

ZELIKOFF, JUDITH T., RALPH SMIALOWICZ, PIERLUIGI E. BIGAZZI, ROBERT A. GOYER, DAVID A. LAWRENCE, HOWARD I. MAIBACH, and DONALD GARDNER. "Immunomodulation by Metals." Toxicological Sciences 22, no. 1 (1994): 1–7. http://dx.doi.org/10.1093/toxsci/22.1.1.

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20

Zelikoff, J. "Immunomodulation by Metals." Fundamental and Applied Toxicology 22, no. 1 (January 1994): 1–7. http://dx.doi.org/10.1006/faat.1994.1001.

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21

Jones, Oliver A. H., Daniel A. Dias, Damien L. Callahan, Konstantinos A. Kouremenos, David J. Beale, and Ute Roessner. "The use of metabolomics in the study of metals in biological systems." Metallomics 7, no. 1 (2015): 29–38. http://dx.doi.org/10.1039/c4mt00123k.

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Metabolomics and systems biology/toxicology can elucidate novel pathways and mechanistic networks of metals and metalloids in biological systems, as well as providing useful biomarkers of the metal status of organisms.

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22

Duffus, John H. "Toxicology of Metals—Science Confused by Poor Use of Terminology." Archives of Environmental Health: An International Journal 58, no. 5 (May 2003): 263–66. http://dx.doi.org/10.3200/aeoh.58.5.263-266.

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23

Kapu, Moses M., and David J. Schaeffer. "Planarians in toxicology. Responses of asexualDugesia dorotocephala to selected metals." Bulletin of Environmental Contamination and Toxicology 47, no. 2 (August 1991): 302–7. http://dx.doi.org/10.1007/bf01688656.

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24

Hostýnek, Jurij J., Robert S. Hinz, Cynthia R. Lorence, Matthew Price, and Richard H. Guy. "Metals and the Skin." Critical Reviews in Toxicology 23, no. 2 (January 1993): 171–235. http://dx.doi.org/10.3109/10408449309117116.

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25

Fuhrmann, G. F. "Handbook of experimental pharmacology, volume 115. Toxicology of metals. Biochemical aspects." Toxicology 108, no. 1-2 (April 1996): 153–54. http://dx.doi.org/10.1016/s0300-483x(96)03314-8.

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26

Ujueta, Francisco, Ana Navas-Acien, Koren K. Mann, Rakesh Prashad, and Gervasio A. Lamas. "Low-Level Metal Contamination and Chelation in Cardiovascular Disease—A Ripe Area for Toxicology Research." Toxicological Sciences 181, no. 2 (February 28, 2021): 135–47. http://dx.doi.org/10.1093/toxsci/kfab026.

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Abstract Cardiovascular disease remains the leading cause of death worldwide. In spite of cardiovascular prevention, there is residual risk not explicable by traditional risk factors. Metal contamination even at levels previously considered safe in humans may be a potential risk factor for atherosclerosis. This review examines evidence that 2 metals, lead, and cadmium, demonstrate sufficient toxicological and epidemiologic evidence to attribute causality for atherosclerotic disease. Basic science suggests that both metals have profound adverse effects on the human cardiovascular system, resulting in endothelial dysfunction, an increase in inflammatory markers, and reactive oxygen species, all of which are proatherosclerotic. Epidemiological studies have shown both metals to have an association with cardiovascular disease, such as peripheral arterial disease, ischemic heart disease, and cardiovascular mortality. This review also examines edetate disodium-based chelation as a possible pharmacotherapy to reduce metal burden in patients with a history of cardiovascular disease and thus potentially reduce cardiovascular events.

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27

Wang, Hao, and Megumi T. Matsushita. "Heavy metals and adult neurogenesis." Current Opinion in Toxicology 26 (June 2021): 14–21. http://dx.doi.org/10.1016/j.cotox.2021.03.006.

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28

OHSAWA, MOTOYASU. "Immunological disturbance and heavy metals." Eisei kagaku 36, no. 4 (1990): 255–66. http://dx.doi.org/10.1248/jhs1956.36.255.

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29

Netter, K. J. "Heavy metals in the environment." Toxicology 72, no. 2 (January 1992): 235–36. http://dx.doi.org/10.1016/0300-483x(92)90115-u.

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30

Grandjean, P. "Toxicology research for precautionary decision-making and the role of Human & Experimental Toxicology." Human & Experimental Toxicology 34, no. 12 (November 26, 2015): 1231–37. http://dx.doi.org/10.1177/0960327115601762.

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A key aim of toxicology is the prevention of adverse effects due to toxic hazards. Therefore, the dissemination of toxicology research findings must confront two important challenges: one being the lack of information on the vast majority of potentially toxic industrial chemicals and the other being the strict criteria for scientific proof usually required for decision-making in regard to prevention. The present study ascertains the coverage of environmental chemicals in four volumes of Human & Experimental Toxicology and the presentation and interpretation of research findings in published articles. Links in SciFinder showed that the 530 articles published in four selected volumes between 1984 and 2014 primarily dealt with metals (126 links) and other toxicants that have received substantial attention in the past. Thirteen compounds identified by US authorities in 2006 as high-priority substances, for which toxicology documentation is badly needed, were not covered in the journal issues at all. When reviewing published articles, reliance on p values was standard, and non-significant findings were often called ‘negative.’ This tradition may contribute to the perceived need to extend existing research on toxic hazards that have already been well characterized. Several sources of bias towards the null hypothesis can affect toxicology research, but are generally not considered, thus adding to the current inclination to avoid false positive findings. In this regard, toxicology is particularly prone to bias because of the known paucity of false positives and, in particular, the existence of a vast number of toxic hazards which by default are considered innocuous due to lack of documentation. The Precautionary Principle could inspire decision-making on the basis of incomplete documentation and should stimulate a change in toxicology traditions and in toxicology research publication.

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31

Sunderman, F. William. "METALS AND LIPID PEROXIDATION." Acta Pharmacologica et Toxicologica 59 (March 13, 2009): 248–55. http://dx.doi.org/10.1111/j.1600-0773.1986.tb02755.x.

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32

Hoberman, Alan M. "Toxicology and Biological Monitoring of Metals in Humans: Including Feasibility and Need." Journal of the American College of Toxicology 6, no. 2 (March 1987): 259. http://dx.doi.org/10.3109/10915818709075140.

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33

Mebs, D. "Toxicology and biological monitoring of metals in humans including feasibility and need." Toxicon 26, no. 8 (January 1988): 757. http://dx.doi.org/10.1016/0041-0101(88)90289-9.

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34

Halmi, M. I. E., and Siti Aqlima Ahmad. "Chemistry, biochemistry, toxicity and pollution of molybdenum: A mini review." Journal of Biochemistry, Microbiology and Biotechnology 2, no. 1 (July 31, 2014): 1–6. http://dx.doi.org/10.54987/jobimb.v2i1.122.

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Molybdenum is used in various industries. Its pollution has been recorded globally and is an emerging pollutant. Molybdenum is poorly represented in the literature as compared to heavy metals such as mercury, chromium, arsenic, lead and cadmium for instance, due to the metalâ€™s low toxicity to humans. It has now been reported that molybdenum is very toxic to embryo and spermatogenesis of fish and mice and this worrying trend would place molybdenum at the forefront of toxicology and bioremediation studies in the future. This mini review attempts to summarize what we know on its chemistry, biochemistry, toxicity and pollution with the hope that this knowledge would be useful for future studies on molybdenumâ€™s removal from the environment.Â

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35

Mohammadi, Mehrnoosh, Alireza Riyahi Bakhtiari, and Saber Khodabandeh. "Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues." Journal of Toxicology 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/413870.

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Breast cancer is the major cause of cancer morbidity and mortality between women in the world. Metals involved in environmental toxicology are closely related to tumor growth and cancer. On the other hand, some metals such as selenium have anticarcinogenic properties. The aim of this study is to determine the concentration of cadmium, lead, mercury, and selenium in separated parts of tegmen, tumor, tumor adiposity, and tegmen adiposity of 14 breast cancer tissues which have been analyzed by graphite furnace atomic absorption (AA-670) and ICP-OES (ULTIMA 2CE). Our results show that Se and Hg have maximum and minimum concentration, respectively. Statistical analysis reveals no significant differences between metal accumulations in different parts of cancer tissues(P>0.05)and this observation might be due to the close relation of separated parts of fatty breast organ. Thus, we could conclude that a high level of these heavy metals is accumulated in Iranian cancerous breasts and their presence can be one of the reasons of cancer appearance.

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36

Kern, Janet K., Bruce D. Grannemann, Madhukar H. Trivedi, and James B. Adams. "Sulfhydryl-Reactive Metals in Autism." Journal of Toxicology and Environmental Health, Part A 70, no. 8 (March 2007): 715–21. http://dx.doi.org/10.1080/15287390601188060.

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37

Gupta, Meenakshi, Ruchika Sharma, and Anoop Kumar. "Docking Techniques in Toxicology: An Overview." Current Bioinformatics 15, no. 6 (November 11, 2020): 600–610. http://dx.doi.org/10.2174/1574893614666191003125540.

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A variety of environmental toxicants such as heavy metals, pesticides, organic chemicals, etc produce harmful effects in our living systems. In the literature, various reports have indicated the detrimental effects of toxicants such as immunotoxicity, cardiotoxicity, nephrotoxicity, etc. Experimental animals are generally used to investigate the safety profile of environmental chemicals, but research on animals has some limitations. Thus, there is a need for alternative approaches. Docking study is one of the alternate techniques which predict the binding affinity of molecules in the active site of a particular receptor without using animals. These techniques can also be used to check the interactions of environmental toxicants towards biological targets. Varieties of user-friendly software are available in the market for molecular docking, but very few toxicologists use these techniques in the field of toxicology. To increase the use of these techniques in the field of toxicology, understanding of basic concepts of these techniques is required among toxicological scientists. This article has summarized the fundamental concepts of docking in the context of its role in toxicology. Furthermore, these promising techniques are also discussed in this study.

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38

Kietzmann, M. "Immunotoxicology of Environmental and Occupational Metals." Toxicon 39, no. 12 (December 2001): 1945. http://dx.doi.org/10.1016/s0041-0101(01)00115-5.

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39

Cooney, J. J., and G. W. Pettibone. "Metals and microbes in toxicity testing." Toxicity Assessment 1, no. 4 (1986): 487–99. http://dx.doi.org/10.1002/tox.2540010408.

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40

Pérez, Adam, and John Pierce Wise Sr. "One Environmental Health: an emerging perspective in toxicology." F1000Research 7 (June 27, 2018): 918. http://dx.doi.org/10.12688/f1000research.14233.1.

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The One Environmental Health research approach, a subspecialty of the One Health initiative, focuses on toxic chemicals. Distinct disciplines work together to give a holistic perspective of a health concern through discrete disciplines, including, but not limited to, public health and the medical and veterinary sciences. In this article, we illustrate the concept of One Environmental Health with two case studies. One case study focuses on alligators and contributions to the field of endocrine disruption. The other case study focuses on whales and contributions to understanding carcinogenic metals. Both studies illustrate how the health of sentinel organisms has the potential to inform about the health of humans and the ecosystem.

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41

Moulis, Jean-Marc, Zorica Bulat, and Aleksandra Buha Djordjevic. "Threshold in the toxicology of metals: Challenges and pitfalls of the concept." Current Opinion in Toxicology 19 (February 2020): 28–33. http://dx.doi.org/10.1016/j.cotox.2019.10.004.

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42

Lodge, James P. "Toxicology and biological monitoring of metals in humans, including feasibility and need." Atmospheric Environment (1967) 21, no. 3 (January 1987): 723–24. http://dx.doi.org/10.1016/0004-6981(87)90063-1.

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43

Polozova, Elena V., V. V. Shilov, A. S. Bogacheva, and I. N. Klyushkin. "THE POSSIBILITY OF USING CYANOBACTERIA SYNECHOCYSTIS SP. FOR THE ASSESSMENT OF THE DEGREE OF WATER POLLUTION WITH HEAVY METAL SALTS." Hygiene and sanitation 96, no. 7 (March 27, 2019): 656–60. http://dx.doi.org/10.18821/0016-9900-2017-96-7-656-660.

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For the first time there are provided data on the toxicity of salts of heavy metals to the cyanobacteria Synechocystis sp. CALU 713 and PCC 6803. Changes of light and temperature conditions were shown to modify cyanobacteria sensitivity to the toxic effect of salts of heavy metals. The toxicity of salts of heavy metals is determined by the dose-dependent effect of the reducing the growth rate of cyanobacteria in the incubation medium on water basis. Changes of light and temperature culture conditions modify the sensitivity of the cyanobacteria Synechocystis sp. to toxic effect of salts of heavy metals. The decrease in temperature and light in various degrees enhances the toxic effect of salts of heavy metals. Morphological changes of cyanobacteria, caused by the toxic action of salts of heavy metals were established to be nonspecific, regardless of the strain and species of the studied toxicant, showing the change of shapes and sizes, including dividing cells. At the ultrastructural level morphological changes in the cells of cyanobacteria are represented by changes of the thickness and the integrity of peptidoglycan layer of the cell wall; the damage to intracellular organelles relevant to energy metabolism: divergent tilakoid membranes with formation of intratilakoid spaces; agglutination of phycobilisomes and accumulation of polyphosphate granules; fibrous transformation of nucleoplasms with the loss of the typical granulation. A strain of Synechocystis sp. CALU 713is the most sensitive to the toxic action of salts of heavy metals and, therefore, suitable for the use in experimental toxicology. Cyanobacteria Synechocystis sp. CALU 713 and PCC 6803 are promising test-object in experimental toxicology for the assessment of the degree of water pollution with heavy metal salts. There were obtained parameters of toxicity of heavy metal salts (AgNO3; 3CdSO4•8H2O; Hg(CH3COO)2; CuSO4•5H2O) for two strains of the cyanobacteria Synechocystis sp. In these circumstances there were revealed morphological changes of the surface ultrastructure of cells of Synechocystis sp.

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44

Facey, Jordan A., Simon C. Apte, and Simon M. Mitrovic. "A Review of the Effect of Trace Metals on Freshwater Cyanobacterial Growth and Toxin Production." Toxins 11, no. 11 (November 5, 2019): 643. http://dx.doi.org/10.3390/toxins11110643.

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Cyanobacterial blooms are becoming more common in freshwater systems, causing ecological degradation and human health risks through exposure to cyanotoxins. The role of phosphorus and nitrogen in cyanobacterial bloom formation is well documented and these are regularly the focus of management plans. There is also strong evidence that trace metals are required for a wide range of cellular processes, however their importance as a limiting factor of cyanobacterial growth in ecological systems is unclear. Furthermore, some studies have suggested a direct link between cyanotoxin production and some trace metals. This review synthesises current knowledge on the following: (1) the biochemical role of trace metals (particularly iron, cobalt, copper, manganese, molybdenum and zinc), (2) the growth limitation of cyanobacteria by trace metals, (3) the trace metal regulation of the phytoplankton community structure and (4) the role of trace metals in cyanotoxin production. Iron dominated the literature and regularly influenced bloom formation, with 15 of 18 studies indicating limitation or colimitation of cyanobacterial growth. A range of other trace metals were found to have a demonstrated capacity to limit cyanobacterial growth, and these metals require further study. The effect of trace metals on cyanotoxin production is equivocal and highly variable. Better understanding the role of trace metals in cyanobacterial growth and bloom formation is an essential component of freshwater management and a direction for future research.

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45

Chen, Qiao Yi, Thomas DesMarais, and Max Costa. "Metals and Mechanisms of Carcinogenesis." Annual Review of Pharmacology and Toxicology 59, no. 1 (January 6, 2019): 537–54. http://dx.doi.org/10.1146/annurev-pharmtox-010818-021031.

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Metal exposure is pervasive and not limited to sporadic poisoning events or toxic waste sites. Hundreds of millions of people around the globe are affected by chronic metal exposure, which is associated with serious health concerns, including cancer, as demonstrated in a variety of studies at the molecular, systemic, and epidemiologic levels. Metal-induced toxicity and carcinogenicity are sophisticated and complex in nature. This review provides a broad context and holistic view of currently available studies on the mechanisms of metal-induced carcinogenesis. Specifically, we focus on the five most prevalent carcinogenic metals, arsenic, nickel, cadmium, chromium, and beryllium, and their potential to drive carcinogenesis in humans. A comprehensive understanding of the mechanisms behind the development of metal-induced cancer can provide valuable insights for therapeutic intervention involving molecular targets in metal-induced carcinogenesis.

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46

Wu, Yao Guo, You Ning Xu, Si Hai Hu, Jiang Hua Zhang, and Jian Guo Li. "Ecological Risk Assessment of Heavy Metals in Contaminated Soil Based on Engineering Fuzzy Set Theory." Advanced Materials Research 113-116 (June 2010): 815–18. http://dx.doi.org/10.4028/www.scientific.net/amr.113-116.815.

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It is not easy to handle relativities of metals toxicology and ecological risk grades, especially, fuzzy in realization of soil heavy metal pollution, when the method suggested by Hakanson was used to assess ecological risk. To explore a better way to solve this problem, certainty in ecological risk grades was fuzzed through engineering fuzzy set theory, and a fuzzy mathematic model was built. The model was then applied in Xiaoqinling gold mining regional, which was selected as case study and where soil was polluted by heavy metals over decades, and its results were compared with that from Hakanson method. The results showed that the fuzzy mathematic model was a better way for ecological risk assessment of heavy metals in contaminated soil.

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47

Crowder, Adèle. "Acidification, metals and macrophytes." Environmental Pollution 71, no. 2-4 (1991): 171–203. http://dx.doi.org/10.1016/0269-7491(91)90032-r.

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48

Baker, A. J. M. "Heavy metals in soils." Environmental Pollution 90, no. 2 (1995): 269. http://dx.doi.org/10.1016/0269-7491(95)90014-4.

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49

Wong, P. K. "Mutagenicity of heavy metals." Bulletin of Environmental Contamination and Toxicology 40, no. 4 (April 1988): 597–603. http://dx.doi.org/10.1007/bf01688386.

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50

Martin, M. H. "Heavy metals in the environment (trace metals in the environment, volume 1)." Environmental Pollution 80, no. 3 (1993): 308–9. http://dx.doi.org/10.1016/0269-7491(93)90056-t.

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Journal articles on the topic 'Metals – Toxicology'

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