Dissertations / Theses on the topic 'Metals – Toxicology'
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Chen, Xuehui. "Accumulation of heavy metals and organochlorine pesticides in human milk and adipose tissues, and its health concerns." HKBU Institutional Repository, 2007. http://repository.hkbu.edu.hk/etd_ra/779.
Full textIntima, Danielle Polidorio. "Avaliação do risco a exposição ocupacional a metais em incineradores de resíduos de serviços de saúde." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/46/46133/tde-23072008-085439/.
Full textThis project aimed to evaluate the risk of metal occupational exposition in hospital waste incinerators, in order to verify the incineration plant work conditions, to protect the workers\' health and to avoid damage to the environment. Hospital waste is septic, characterized as Hazardous Waste (Class I) due to its patogenicity, therefore their study is extremely important for public health and environment quality. One of the legally recommended treatment processes to this kind of waste is the incineration. This process is based on thermal decomposition by oxidation, to minimize the toxicity and the waste volume. The presence of metal in the waste to be incinerated is a concern, because this process causes the partition of the metal present in the feeding waste of the combustion camera, which could lead to its emission together with the ash or even with the pollution control system waste, or, even, through the chimney, depending on its volatility. Due to this issue, occupational risk evaluation generated by exposition to particulate material and toxic gases emitted by the process rests necessary. This evaluation consists of particle characterization by measuring the constituents in mass per volume of the environmental sampling air. In order to reach it, specific and recognized methodology from the National Institute of Organization Safety Health (NIOSH) was applied, which recommends for mercury sampling the use of hopcalite resin, and for the other metaIs the use of cellulose filter. As analytic techniques, this institute recommends the use of cold vapor atomic absorption spectrometry to mercury determination and the inductively coupled plasma emission spectrometry to the other metals. According to the results, the obtained concentrations were above the limit established for arsenic, beryllium, cadmium, lead and mercury. Therefore, technological alterations were proposed in the process and adaptation of the protection equipments, in order to protect the employees\' health, the population health and to avoid damage to the environment.
Ramos, Teresinha Aparecida Dias. "Exposição a metais em pescadores do alto Rio São Francisco, Brasil: um estudo preliminar." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-16112017-110000/.
Full textA preliminar study to estimate the exposure to metals by fishermen at the High San Francisco River area in Minas Gerais State, in Brazil, had been accomplished in 2006. The fishemen at Tres Marias and Morada Nova county in Minas Gerais State (used a control group), had been evaluated under a clinical and laboratorial point ofview, through a biochemical analysis and Pb-B; Cd -D, As -D, ZnD and Mn-D determinations. The results apparently presented a significant statistical differences related to Zinc and Arsenic among the evaluated fisherman groups. It was not found statistically relevant differences for Manganese and Lead. For urinary Cd, the results were identical at both cities. Although the possibility of exposure by those metals have been studied, there are no evidences of fishermen\'s health implications yet.
Yu, Lok Chiu. "Cellular metabolism in in vitro toxicity and toxicology studies." HKBU Institutional Repository, 2005. http://repository.hkbu.edu.hk/etd_ra/675.
Full textZheng, Wei. "Defense of mammalian body against heavy metal-induced toxicities: Sequestration by the choroid plexus and elimination via the bile." Diss., The University of Arizona, 1991. http://hdl.handle.net/10150/185389.
Full textSekhula, Koena Sinah. "Heavy metal ion resistance and bioremediation capacities of bacterial strains isolated from an Antimony Mine." Thesis, University of Limpopo, 2005. http://hdl.handle.net/10386/139.
Full textSix aerobic bacterial strains [GM 10(1), GM 10 (2), GM 14, GM 15, GM 16 and GM 17] were isolated from an antimony mine in South Africa. Heavy-metal resistance and biosorptive capacities of the isolates were studied. Three of the isolates (GM 15, GM 16 and GM 17) showed different degrees of resistance to antimony and arsenic oxyanions in TYG media. The most resistant isolate GM 16 showed 90 % resistance, followed by GM 17 showing 60 % resistance and GM 15 was least resistant showing 58 % resistance to 80 mM arsenate (AsO4 3-). GM 15 also showed 90 % resistance whereas isolates GM 16 and GM 17 showed 80 % and 45 % resistance respectively to 20 mM antimonate (SbO4 3-). Arsenite (AsO2 -) was the most toxic oxyanion to all the isolates. Media composition influenced the degrees of resistance of the isolates to some divalent metal ions (Zn2+, Ni2+, Co2+, Cu2+ and Cd2+). Higher resistances were found in MH than in TYG media. All the isolates could tolerate up to 5 mM of the divalent metal ions in MH media, but in TYG media, they could only survive at concentrations below 1 mM. Also, from the toxicity studies, high MICs were observed in MH media than TRIS-buffered mineral salt media. Zn2+ was the most tolerated metal by all the isolates while Co2+ was toxic to the isolates. The biosorptive capacities of the isolates were studied in MH medium containing different concentrations of the metal ions, and the residual metal ions were determined using atomic absorption spectroscopy. GM 16 was effective in the removal of Cu2+ and Cd2+ from the contaminated medium. It was capable of removing 65 % of Cu2+ and 48 % of Cd2+ when the initial concentrations were 100 mg/l, whereas GM 15 was found to be effective in the biosorption of Ni2+ from the aqueous solutions. It was capable of removing 44 % of Ni2+ when the initial concentration was 50 mg/l. GM 17 could only remove 20 % of Cu2+ or Cd2+. These observations indicated that GM 16 could be used for bioremediation of xvi Cu2+ and Cd2+ ions from Cu2+ and Cd2+-contaminated aqueous environment, whereas GM 15 could be used for bioremediation of Ni2+.
National Research Foundation and the University of the North Research Unit
Wilkins, Janine Catherine. "Cadmium tolerance in Holcus lanatus L. : studies of stability and differential cadmium uptake in two ecotypes." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297644.
Full textNkqenkqa, Vuyiseka. "Metal and microbial contamination of agricultural soil and the Veldwachters River, Stellenbosch, South Africa." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2423.
Full textSurface water is used as a source of water supply in many countries, including South Africa. One of the sources of surface water pollution is leachate and surface runoff from landfills. In agricultural soils, the landfill runoff and leachate deteriorate the quality and affect the fertility of soil. The entry of metals and microorganisms from landfill leachate to adjacent environments is through surface runoff due to rainfall. Adverse effects on human- and environmental health triggers a need to monitor and control contaminants in the environment. The aims of the study are to determine the effect of landfill runoff and leachate on agricultural soil and river water (Veldwachters River) running adjacent to the Devon Valley landfill site and to identify potential metal-tolerant organisms in environmental samples collected in Stellenbosch, Western Cape, South Africa. Samples (agricultural soil, river water and sediments) were collected once a month for a period of six months from the study area for analysis. Physicochemical parameters that are known to have major effects on environmental samples were assessed and the concentrations of various metals (Al, Pb, Cr, Mn, Mo, Co, Ni, Cu, Zn, Fe, Cd and V) were also determined by means of inductively coupled plasma mass spectrometry (ICP-MS). Soil texture analysis was tested in order to monitor the metal distribution in soils under the influence of environmental factors.
Gausman, Maria M. "A COMPARISON OF DUCKWEED AND STANDARD ALGAL PHYTOTOXICITY TESTS AS INDICATORS OF AQUATIC TOXICOLOGY." Miami University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=miami1153752259.
Full textSantos, Claudia Regina dos. "Avaliação dos indicadores biológicos de exposição aos metais em trabalhadores de fundições." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-13012012-104922/.
Full textThe sanitary metal production is a sector in constant development in Brazil. This industrial process involves stages such as evaporation, condensation and oxidation of metals, therefore allowing the formation of metallic fumes in some types of industry, and also in foundries. The contaminated environment can induce, in the workers, biochemical alterations and, in some circumstances, occupational diseases. In the sanitary metal sector, alloys are used in which predominate the metals zinc and copper, being lead, cadmium, manganese and nickel, metals that can be found in the form of impurities. According to Brazilian legislation\'s (Ministry of Work) only lead in blood and cadmium in urine are regulated as biological monitoring of exposure. In the present study, methods based on graphite furnace atomic absorption spectrometry and zeeman background correction were validated for quantification of Pb-B, Cd-U, Mn-U and Ni-U, and 273 male individuais (178 exposed group and 95 non exposed - control group), working in 8 sanitary metal foundries, in Loanda, Paraná, a state located in the south of Brazil, were evaluated. The levels of Pb-B were higher than the international permissible limit. Relatively low concentrations were found for the other evaluated metals: Cd-U, Mn-U and Ni-U, thus lead can be considered, in this case, the main problem, associated with metallic fumes. Corrective measures in the work environment were proposed and implemented, thus the four metais were evaluated in two distinct situations (biological determinations were done before and after the modifications). The results of the second evaluation showed reductions those were statistically significant. The means obtained in the two determinations were 42,74µg/dL and 26,54µg/dL for Pb-B; 0,269 and 0,015µg/g creatinine for Cd-U; 1,94 and 0,39µg/g creatinine for Mn-U and 1,82 and 0,68µg/g creatinine for Ni-U, with leveis of significance (p) < 0,05, thus evidencing the importance of the adequacy of the work environment in the guarantee of safe exposures for the workers.
Campos, Bruno Galvão de. "Avaliação do risco ecológico de metais em sedimentos da Baía de Guanabara (RJ), através de um método escalonado baseado em múltiplas linhas de evidências /." São Vicente, 2017. http://hdl.handle.net/11449/148708.
Full textResumo: A Baía de Guanabara concentra aproximadamente 70% das indústrias do Estado do Rio de Janeiro. Os resíduos produzidos por essas fontes, somados à carga de esgoto doméstico, transformaram a região em umas das áreas mais poluídas da costa Brasileira. O presente estudo realizou a avaliação do risco ecológico dos metais em sedimentos da Baía de Guanabara, por meio de um método escalonado utilizando múltiplas linhas de evidência: caracterização do sedimento quanto à sedimentologia e concentração de metais, comparação das concentrações ambientais com guias de qualidade de sedimento, ensaios de toxicidade crônica utilizando os organismos Anomalocardia brasiliana e Nitocra sp., ensaios de toxicidade aguda utilizando os organismos Tiburonella viscana, Kalliapseudes schubartii, e Anomalocardia brasiliana. Para comprovar existência de relação causa e efeito entre os metais e a toxicidade, foram empregadas a técnica do TIE, análises multivariadas (PCA) e matrizes qualitativas. Os sedimentos mostraram níveis altos a moderados de metais (Zn, Pb, Cu, Cr) associados com a toxicidade. O TIE revelou que, além dos metais, amônia e compostos orgânicos são contaminantes presentes na região que tem a capacidade de causar toxicidade. Desse modo constatou-se que os metais constituem uma importante classe de contaminantes para a Baía de Guanabara, os quais, além de estarem presentes em altas concentrações, interagem com outros contaminantes e são também (co)responsáveis por efeitos biológicos negativos
Abstract: The Guanabara Bay (GB) comprises approximately 70% of the industries of Rio de Janeiro State. The wastes produced by these sources, combined with the domestic sewage loads, have transformed the region into one of the most polluted areas of the Brazilian coast. The present study evaluated the ecological risk of metals in sediments from the GB by the use of a tiered approach. The chosen method combines the following lines of evidence: geochemistry, comparison of environmental concentrations of metals with sediment quality guidelines, chronic sediment toxicity tests with Anomalocardia brasiliana and Nitocra sp.; and acute sediment toxicity tests with Tiburonella viscana, Kalliapseudes schubartii, and Anomalocardia brasiliana. To verify the existence of cause and effect relationships between metals and toxicity, the Toxicity Identification Evaluation (TIE) technique, multivariate analysis (PCA) and qualitative matrices were used. Sediments showed high to moderate levels of metals (Zn, Pb, Cu, Cr) associated with toxicity. In addition, the TIE has revealed that metals, ammonia and organic compounds contribute to cause sediment toxicity. We concluded that metals are an important class of contaminants for the GB, together with other chemicals, as they are present in high concentrations, interact with other substances and are (co)responsible for the negative biological effects
Mestre
Nightingale, Leigh. "The toxic effect of heavy metals on algal biomass (Spirulina sp.) and carbonic anhydrase activity, an enzyme which is central to algal application in metal precipitation." Thesis, Rhodes University, 2004. http://hdl.handle.net/10962/d1007858.
Full textNgule, Chrispus M. Jr. "In Vitro Adsorption of Heavy Metals Using Metal-Organic Frameworks." Youngstown State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1597664070125999.
Full textBryson, Stuart Edwin. "A Geochemical Characterization of Streams Surrounding the Tom and Jason SEDEX Deposits of the MacMillan Pass, Yukon, Canada: Implications for Mineral Exploration and Toxicology." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/35781.
Full textBryant, Joshua Lee. "Incorporating Ground Beetle (Coleoptera: Carabidae) Assemblage Data and Earthworm Bioassays in the Ecological Risk Assessment of a Trap and Skeet Shooting Range." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1275411039.
Full text陳慶文 and Hing-man Chan. "An ecotoxicological study of trace metals in the green-lipped mussel Perna viridis (L.) (Bivalvia : Mytilacea)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1987. http://hub.hku.hk/bib/B3120806X.
Full textFelix, JoÃo Ermeson Mota. "SÃntese de sÃlica mesoporosa de grande Ãrea superficial para o tratamento de efluentes e sua aÃÃo conjunta com CaCO3 e o extrato aquoso da folha da bananeira contendo taninos." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9822.
Full textThis work consists in the synthesis of mesoporous silica of high surface area and its use for wastewater treatment in the removal of toxic metals and organic compounds, and their use together with CaCO3 and aqueous extract of the leaves of the plant Musa spp (Banana) that probably contains tannins. There are several studies on the use of mesoporous silica, vegetable tannin and calcium carbonate, which have efficiency in the removal of toxic metals and organic compounds of bodies of water and wastewater. Silica is an inorganic polymer of formula minimum SiO2, with many studies using silica show its efficiency in removing the majority of contaminants from water by adsorption and / or precipitation with organic or inorganic contaminants such and the silica may still be used several times after its purification. The tannins are polihidroxifenois of plant origin (with mass between 500 and 3000 g / mol) and CaCO3 is a mineral with many uses. As tannins, the use of calcium carbonate to sewage treatment has proved to be a simple and efficient method. As a sample for testing for metal removal using the compounds separately and then together we used a standard solution of the salts of toxic metals of the 1st and 3rd groups analytical containing the transition metals of the periodic table and Al3+, which groups are Analytical known concentration (1st group: Ag+, Pb2+ HG22+; 3rd group: Al3+, Cr2+, Fe2+, Mn2+, Zn2+, Co2+ and Ni2+), where the tests were done and efficiency additions of compounds to remove the contaminants. Both tests of efficiency and plus shown remove much of micro organic and inorganic pollutants, and the concentration of organic compounds measured by COD reduced to levels below 5 mg / l and metals such as Al3+, Fe2+ and Pb2+ were removed from the solution 95% efficiency compared to the initial concentration.
Chapman, Kimberly K., Phillip R. Scheuerman, G. Lanza, D. Nelson, and R. Brinkhurst. "Comparative Study of Three Oligochaete Species as Indicators of Metals in a Sediment Toxicity Bioassay." Digital Commons @ East Tennessee State University, 1995. https://dc.etsu.edu/etsu-works/2905.
Full textO'Malley, Kristen Marie. "Comparative sensitivity of the early life history stages of the Blue Crab, callinectes sapidus, to mercury exposure." Thesis, Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/25200.
Full textFung, Chi-tuen, and 馮志端. "Approaches to assess heavy metal toxicity in the marine environment." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B45013378.
Full textYellowhair, Monica. "The Chemical-Induced Genotoxicity of Depleted Uranium." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/202509.
Full textPaul, Jenny Sueanna. "ECOLOGICAL AND SOCIOLOGICAL IMPLICATIONS OF TISZA RIVER MINE TAILINGS POLLUTION AND EFFECT OF CHRONIC CADMIUM EXPOSURE ON FISH PHYSIOLOGY." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/dissertations/1450.
Full textBrossi, Maria Julia de Lima. "Ecotoxicologia de um sistema florestal de eucalipto tratado com lodo de esgoto." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/64/64135/tde-29112009-162251/.
Full textThe application of sewage sludge in forest systems quests the improvement of the production, favoring the physical, chemistries and biological characteristics of the soil and of the plants. However, the sludge can contain pathogen and, organic and inorganic toxics elements, and the effect of these pollutants in the soil and in the plant is still unknown. It was established the hypothesis that the sewage sludge, when applied to the soil, according to the norm P4.230 of CETESB, doesn\'t cause toxics effects to the soil-eucalyptus system. To test the hypothesis above, it was established as objective, the determination of the concentration of the potentially toxics elements, the evaluation of the toxicity and genotoxicity of the sewage sludge treated soil, and the verification of the correlation among those variables. The field experiment was conducted in December of 2004, when seedlings of Eucalyptus grandis were planted and treated with sewage sludge, in the doses of 0; 7,7; 15,4 and 23,1 tha 1, dry base, in commercial area of eucalyptus cultivation of the Suzano Bahia Sul Papel and Celulose S.A company, in Itatinga, SP. Soil samples were collected to the 18, 21, 24, 27 and 34 months after the application of the sludge. They were established the concentrations of Cr, Mn, Fe, Ni, Cu, Zn, Cd and Pb in the soil, extracted for DTPA, Mehlich-1 and with concentrated HNO3+HCl, and quantified by ICP-MS. The toxicity of the soil was evaluated through the tests with D. magna (lethal concentration -LC50), with Pseudokcrichirella subcaptata (growth inhibition - IC50), with Lactuca sativa (root growth) and with Allium cepa (mitotic index, cromossomic aberration and micronucleus). The results showed an increase in the concentrations of Cr, Mn, Fe, Ni, Cu, Zn, Cd and Pb in the soil in agreement with the doses. An increase of the toxicity was observed for D. magna, P. subcaptata and an increase of the genotoxicity and mutagenicity for A. cepa in agreement with the doses. The applied sewage sludge to the soil in the dose of 15,1t ha-1, recommended by CETESB, doesn\'t cause toxic, genotoxic or mutagenic effect in the system soilplant, in agreement with the accomplished tests. There is correlation among the toxicity tests with P. subcaptata, of mutagenicity with A. cepa (micronucleus) with the concentrations of Cr, Mn, Fe, Ni, Cu, Zn, Cd and Pb in the soil. The test with D. magna is an important tool in the toxicological evaluation of the sludge applied to the soil, however it wasnt correlated with the concentration of potentially toxics elements in the soil, indicating that the toxicity of the sludge can also be related to the other toxic organic compound or pathogen agents. The L.sativa toxicity test is inadequate in the toxicological evaluation of the sludge application, according to the doses, for reflecting effects of the nutrients and it doesnt reflect the toxic components of the sludge, however it reflects the toxicity in agreement with the time of residue application
Monahan, Jennifer L. "Skeletal Pathology of Tibiotarsi in Chick Embryos Exposed to Platinum Group Metals by Micro-Raman Spectroscopy." Wright State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=wright1278554763.
Full textArnolds, Judith Lize. "Oxidative stress responses in the aquatic macrophyte, Ceratophyllum Demersum L., as biomarkers of metal exposure." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2649.
Full textMetal pollution in aquatic environments is considered a major environmental concern because of variation in several abiotic factors that impose severe restrictions on organisms living in these areas. Ceratophyllum demersum L. (family Ceratophyllaceae), a hornwort or coontail, free floating rootless macrophyte has been suggested a suitable model for investigating metal stress and was used in the current study. This study assessed the use of selected biological responses, namely antioxidant responses and changes in chlorophyll concentration in Ceratophyllum demersum L., as biomarkers of metal exposure, and also investigated the field application of these responses in the Diep River. The ultimate aim was also to determine the usefulness of C. demersum as model of metal contamination and as phytoremediator after a pollution event. An investigation of metal bioaccumulation in this macrophyte exposed to different concentrations of a combination of metals over a five-week exposure period in a greenhouse, was undertaken, as well as a field study in the Diep River, Milnerton, Cape Town and a pond (reference site) at the Cape Peninsula University of Technology, Cape Town, to validate experimental results. In the laboratory study the water was contaminated once off at the beginning of the study, to simulate a pollution event. The metal concentrations in the water and plants were measured in the four treatments and the control every week over a five-week exposure period. The samples were acid-digested and analysed with an Inductively-Coupled Plasma-Mass Spectrophotometer (ICP-MS). The results showed that concentrations of the metals in the water varied in all treatments over time with no specific patterns amongst the treatment groups. This macrophyte proved highly effective in the bioaccumulation of these metals at all four exposure concentrations. The metals bioaccumulated rapidly in the plants after the water was spiked. The main focus of the study was to investigate the possible use of biochemical responses in C. demersum as possible biomarkers for metal exposure. A range of antioxidant/oxidative stress parameters were measured in the plant exposed to a combination of metals (Al, Cu, Fe, Zn) in four different treatments over the five week exposure period. Total antioxidant capacity (TAC) was measured using Total Polyphenols (TP), Ferric Reducing Antioxidant Power (FRAP) and Oxygen Radical Absorbance Capacity assay (ORAC), enzyme activity was determined using Catalase (CAT), Superoxide Dismutase (SOD), Ascorbate Acid (AsA) and Total Glutathione (GSHt) and lipid peroxidation was measured by using Thiobarbituric Acid Reactive Substances (TBARS) and Conjugated Dienes (CDs). The cocktail of the four metals induced significant changes in the antioxidant defence system of C. demersum, including the antioxidant enzyme activities. The different metal exposures disturbed the cellular redox status in the plant. The current study has demonstrated that this macrophyte shows tolerance to metal-induced oxidative stress and that it can survive under relatively high concentrations of these metals by adapting its antioxidant defence strategies. Chlorophyll was extracted in 80% chilled acetone in the dark and the absorbance values were determined using a spectrophotometer. Chlorophyll a (chl a), chlorophyll b (chl b) and total chlorophyll (chl t) contents were measured under different exposure concentrations of metals in the macrophyte. The results of this study indicated that chlorophyll contents were variable over the exposure period and no significant differences in chlorophyll concentrations were found between weeks. A field study in the Diep River and the pond located at the CPUT campus (reference site) was conducted to validate experimental results. Plants in a polluted section of the Diep River were shown to bioaccumulate metals to high concentrations. Bioaccumulation of metals in C. demersum might have induced oxidative stress, and other environmental factors such as temperature- and chemical stress might have caused chlorophyll degradation. The chlorophyll concentrations in the plants of the pond (reference site) might also have been affected by temperature and chemical stress of the water. Significantly higher AsA, CAT, ORAC, SOD and TBARS concentrations in the Diep River plants might be an indication that the plants in the river might be well adapted to the constant exposure to metals and that the plants might have developed a tolerance mechanism to cope with oxidative stress compared to those of the pond. The results show that metals are bioaccumulated quickly by C. demersum after the water is contaminated with metals, i.e. after the "pollution event". However, over time, metals are continuously exchanged between the plants and the water, accounting for the fluctuations in metal concentrations observed over time. This study has shown that C. demersum has phytoremediation potential because it was able to remove high concentrations of metals from the contaminated water. Therefore, C. demersum, can be applied as a model for metal contamination and a phytoremediator after a pollution event. The potential to antioxidant responses and chlorophyll content as biomarkers of metal exposure in C. demersum have been demonstrated.
Gómez, Ramírez Pilar. "El Búho real (Bubo bubo) como especie biomonitora de contaminantes ambientales persistentes en el Sureste de España." Doctoral thesis, Universidad de Murcia, 2011. http://hdl.handle.net/10803/52186.
Full textBiomonitoring studies with raptor birds can be used to evaluate environmental pollution and consequencies to human and environmental health. Levels of metals and insecticides in blood of eagle owl chicks from Southeastern Spain were in general low, being lead levels significantly higher in individuals born in an ancient mining area. The enzime δ-ALAD is a sensitive biomarker of exposure and effect to lead in this species. The study of organochlorine and PBDEs in unhatched eggs suggests dietary shifts or pollutant sources. Eggshell thickness decreased with increasing p,p’-DDE, reaching a level related to population declines in birds when DDE levels exceded 100 ng/g lipid weight. The development of a new tecnique permited the detection of rodenticide residues in 83% of the liver samples.
Santos, Paulo Roberto dos. "Compostos de coordenação do ácido valproico e metais de transição como medicamentos." reponame:Repositório Institucional da UCS, 2014. https://repositorio.ucs.br/handle/11338/879.
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Valproic acid (VPA) is a first-line drug in the treatment of seizures in general, but the side effects from high doses produce liver damage by metabolism. VPA has high affinity for transition metals and produces chemically stable coordination compounds. The present study aimed to synthesize four complexes VPA with Cu+2 and Zn+2 with 1,10- phenanthroline and 2,2’-bipyridine linked aromatic diimines, determine the chemical structures by FAAS, FTIR, ESI-TOF MS , 1H NMR and 13C NMR, evaluate the antioxidant activities by Sod-like and Cat-like and determine acute cytotoxicity front of Artemia salina (brine shrimp) and CHO cell culture. The synthesis procedure began with the preparation of precursor compounds Cu2(Valp)4 (1) and Zn2(Valp)4 (2) by the reaction of Sodium Valproate with chlorides of metals in aqueous medium. The chemical structures were confirmed by MP, FAAS, FTIR, 1H NMR and 13C NMR. Coordination compounds Cu(Valp)2(1,10-Phen) (3) Cu(Valp)2(2,2- Bipy).H2O (4), Zn(Valp)2(1,10-Phen).H2O (5) and Zn(Valp)2(2,2-Bipy).H2O (6) (unpublished) were synthesized by equimolar reaction of compounds 1 and 2 with the corresponding neutral ligands 1,10-phenanthroline and 2.2-bipyridine in DMF solvent. The data of chemical structures of compounds 3 and 4 were obtained by MP, UV-Vis, FAAS, FTIR and ESI-TOF MS and confirmed by comparison with the literature data. Compounds 5 and 6 (unpublished) were analyzed for MP, UV-Vis, FAAS, FTIR, ESI TOF-MS, 1H NMR and 13C NMR, and their chemical structures were confirmed by comparison with the literature (5) and interpretation spectra (6). The Sod-like experiments for compounds 3, 4, 5 and 6 were not significant, but all showed activity of Cat-like. The experiment of acute cytotoxicity in A. saline showed significant for compounds 3, 4, 5 and 6 in 8 different concentrations tested results. Compound 3 was found to be the most toxic (LC50: 2 mg mL-1), followed by compound 5 (LC50: 78 mg mL-1), compound 4 (LC50: 386 mg mL-1) and less toxic compound 6 (LC50: 409 mg mL-1). It can be observed correlation affix the higher toxicity of the compounds with copper, the case that observed for similar compounds with 1,10-Phen. The experiments of acute cytotoxicity of compounds 5 and 6 against CHO cell lines after 24 hours of exposure at concentrations of 25, 20, 15, 10, 5 and 2 μg mL-1 showed no significant differences in toxicities to controls. The results corroborate the results obtained using the A. salina.
Chen, Xunwen. "Expressions of transporters of arsenite and phosphate in rice (Oryza sativa L.) associated with arbuscular mycorrhizal fungi." HKBU Institutional Repository, 2012. https://repository.hkbu.edu.hk/etd_ra/1464.
Full textWong, Nga Cheung. "Effects of algae (Isochrysis galbana) and humic acids on copper toxicity to polychaete (Hydroides elegans) larvae." HKBU Institutional Repository, 2005. http://repository.hkbu.edu.hk/etd_ra/665.
Full textWu, Chuan. "Effects of radial oxygen loss (ROL) on arsenic tolerance, uptake and distribution by rice (Oryza sativa L.)." HKBU Institutional Repository, 2011. http://repository.hkbu.edu.hk/etd_ra/1246.
Full textHunnestad, Annie Vera. "The Effects of Macronutrient Enrichments (ammonium) on the Distribution of Four Bioactive Trace Metals (Cd, Mo, Ni, Cu) in Seawater and Planktonic Biomass." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for kjemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-18370.
Full textSlabber, Michelle Yvonne. "Accumulation and toxicity of metals in oysters (Striostrea margaritacea) from the South African South Coast." Thesis, Cape Peninsula University of Technology, 2013. http://hdl.handle.net/20.500.11838/2037.
Full textThe current status of metal pollution off the South African South coast is not well known. This study was the first to be undertaken in many years using Striostrea margaritacea as a subject species. The aims of the study were to determine the degree of metal contamination in the water, sediments, oyster tissues and oyster shells at sites selected in Witsand, Wilderness and Goukamma, as well as to establish if Striostrea margaritacea qualifies as a successful biomonitor when using lysosomal destabilization as a tool. Seasonal variations between sites were also considered. Other objectives, such as the potential of a Marine Protected Area (MPA) as a control site and the necessity of a monitoring program along the south coast were also included. Sites were sampled seasonally for one year at spring low tides. Ten oysters were collected from each individual site upon each visit. The Neutral Red Retention Time (NRRT) assay was used to determine lysosomal membrane integrity of oyster haemocytes, whereafter oysters were sacrificed for metal analyses. Metals that were analysed are aluminium (Al), copper (Cu), zinc (Zn) and iron (Fe). Metal analyses were done using an Inductively Coupled Plasma - Atomic Emission Spectrometer (ICP- AES). All statistical analyses were performed using ANOVA on Ranks to determine if there were significant differences between sites and between sampling occasions. Aluminium concentrations found in the water column at all sites were considered as low. Iron, zinc and copper concentrations within the water column can on the other hand be considered as high when comparisons are drawn with other studies and data sets. Sediment concentrations for all the metals within the present study were considered to be low when compared to other studies and guidelines. There were not many significant differences recorded between sites and no seasonal patterns were present. Within the tissues of the oysters, the metal ranges are considered to be low when compared to other studies. No definite conclusion about the contamination status of the oyster tissue could be drawn due to the lack of comparative literature. A field study in conjunction with a laboratory experiment should yield more reliable results. There were also no seasonal trends present and very few differences between sites. The bioaccumulation factors were considered as being low with a few exceptions where they were moderate when oyster tissue data was compared to water and sediment data. Concentrations for Al, Zn and Cu in the shells could be considered low when comparisons are drawn, with the exception of Fe that was found to be high. The bioaccumulation factors were considered to be low when oyster shell concentrations were compared to water and sediment data. There were also no seasonal trends present and a prolonged sampling period is suggested to further investigate these findings. When a comparison was drawn between the tissue and shell data a clear pattern was evident. Al and Fe concentrations were highest within the shell where as Zn and Cu concentrations were highest within the tissues of the animal. The theory of mineralization is supported by these findings where bivalves will use their shell as a reservoir for micronutrients and other substances. The NRRT assay revealed that lysosomal membrane destabilization had occurred and that the animals appeared to be stressed for the duration of the sampling period. Site 3, within the MPA, had the longest retention time. The retention times that were recorded were short when compared to other studies. This assay did however show potential as a basic monitoring tool from which more thorough investigations can be initiated. In conclusion, the study sites along the south coast of South Africa does not seem to be contaminated by Al, Zn, Cu or Fe when data is compared to international and local water quality guidelines, sediment quality guidelines and other studies. Also, as concentrations between sites did not differ greatly, it is inconclusive whether or not the MPA can be used as a reliable references site for in situ studies. More vigorous and lengthy studies should be undertaken to contribute to current knowledge of our indigenous species, Striostrea margaritacea and to aid in the development of better management of this resource as well as an ongoing monitoring programme.
VonHandorf, Andrew P. "Cr(VI) Disrupts Chromatin Architecture." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595243461574043.
Full textLou, Laiqing. "Arsenic uptake, accumulation and tolerance in Chinese brake fern (Pteris vittata L., an arsenic hyperaccumulator) under the influence of phosphate." HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/928.
Full textRhora, Jennifer. "Effect of Chromium VI on the Production and Behavior of Lytechinus variegatus (Echinodermata: Echiniodea)." Scholar Commons, 2005. https://scholarcommons.usf.edu/etd/833.
Full textStahler, Adam Christopher. "Micro-Raman Imaging and Hyperspectral Analysis of Tibiotarsi from Chick Embryos Exposed to Sublethal Doses of Platinum Group Metals." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1347480100.
Full textShumba, Trust. "Removal of heavy metals from CRUD and slime dam material using soil washing and bioremediation." Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/1536.
Full textFelix, Fabiana da Silva. "Avaliação ambiental de exposição a fumos metálicos em fundições." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/46/46133/tde-18092015-163514/.
Full textThe Universidade de São Paulo, Instituto de Química e Faculdade de Ciências Farmacêuticas (University of São Paulo, Institute of Chemistry and Pharmaceutical Sciences College) and FUNDACENTRO have developed a project at the manufacturing facilities of stopcocks and faucet parts in Loanda/PR, aiming the evaluation of workplaces. Considering the stages of the brass foundry process in manufacturing those products, there are metallic fumes, originating from metal melting and pouring, which can result in human intoxication and, therefore, it is necessary to make an assessment of the occupational exposure. This assessment consists of collecting the particulate, measuring the mass of the contaminant, and then calculating the concentration by dividing the mass by the volume of sampled air. For particulates, concentration is expressed as µg m-3. For this assessment, it was applied a specific and recognized method of the National Institute of Organization Safety Health (NIOSH) which recommends the use of the technique of inductively coupled plasma optical emission spectrometry (ICP OES) to determine As, Cd, Mn, Ni and Pb in air samples. It was proposed an alternative method using the anodic stripping voltammetry with hanging mercury drop electrode (HMDE) to determine Cd and Pb, in addition to cathodic adsorptive stripping voltammetry with HMDE to determine Ni and cathodic stripping voltammetry with boron-doped diamond electrode to determine Mn. For these procedures were used square wave voltammetry to record all the voltammograms. According to the results of this work, we proposed technological changes in the production process and the adequacy of protection equipment in order to protect the health and well-being of workers, as well as to avoid damages to the environment.
Sanchez, Chardi Alejandro. "La musaranya comuna, Crocidura russula (Hermann, 1780), com a bioindicador en estudis ecotoxicologics." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/129847.
Full textIn this report, a quantification of biomarkers of exposition (accumulation of Pb, Hg, Cd, Tl, Fe, Mg, Zn, Cu, Mn, Mo, Co, Ni, Cr, Sr, Ba and B in soft and hard tissues) and effect (morfometry, haematology, enzymatic activity, genotoxicity and histopathology) in a total of 243 specimens of the greater white-toothed shrew, Crocidura russula (Hermann, 1780) was found. In the present study, the age- and sex-dependent variations were also considered in order to explain the variability due to these important biotic factors. The study sites were 4 polluted sites and 4 reference sites selected both for their environmental relevance (6 out the 8 sites have granted partial or total protection status) and for the interest for the society: the landfill of Garraf, the bigger dump site in the Iberian Peninsula; the abandoned mine of Aljustrel in the Portuguese part of the Iberian Pyrite Belt (IPB); the National Park of Doñana affected by the wastes of the mine of Aznalcóllar, sited in the Spanish part of the IPB; and the Ebro Delta disturbed during decades by several human activities including hunting, industries and domestic wastes. A total of 138 shrews were captured for ecotoxicological studies in 3 polluted sites (Garraf, Aljustrel, and Doñana) and 105 specimens were captured for other ecological studies and stored in a zoological collection (Ebro Delta). Especially in the polluted sites studied, there were marked differences between the bioaccumulation patterns of essential and non-essential elements due to differences in the bioavailability, toxicity, and transfer and bioaccumulation throughout the food chains between the two groups of elements. The highest increases in the tissues of shrews from the polluted sites were on non-essential heavy metals (Pb, Cd, Hg, Tl, and Ni), without metabolic regulation of tissular levels in mammals that ends in high burdens in soft and hard tissues when bioavailability increase in the environment. Among elements quantified, only Pb, Hg, Cd, and, probably Tl, Ni, B, Ba and Sr, were accumulated till levels that may produce toxic effects in mammals. The scarce information of the effects of chronic exposure in natural populations of insectivores render more relevant the use of a battery of biomarkers of effect, that serve as reference values for the species and as assessment of toxic effects in organism. Decreases of body mass and GST activity and increases of mass and pathologies attributable to pollution in liver and kidneys were detected in shrews from the polluted sites. Among biotic factors, age was important because 10 of the elements quantified, with special remark on Cd, showed differential bioaccumulation patterns in juveniles and adults. In contrast, only slight differences in bioaccumulation of Pb, Hg, Ni, Mo, Mn, Co, and Fe were found between males and females. The same pattern of importance of age and sex as in the biomarker of exposure was found in the biomarkers of effect. The use of several biomarkers of exposure and effect provide information of the whole toxic effects of pollution in the normal function of biological systems and point out C. russula as a suitable bioindicator of environmental pollution, specially to evaluate environmental risk both in protected sites and human populations.
Ramalingam, Malarvili. "Metal exposure in non-occupationally exposed pregnant women of Western Australia and contribution of environmental sources." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2011. https://ro.ecu.edu.au/theses/450.
Full textHitron, John Andrew. "AN OPTIMIZED SOLID-PHASE REDUCTION AND CAPTURE STRATEGY FOR THE STUDY OF REVERSIBLY-OXIDIZED CYSTEINES AND ITS APPLICATION TO METAL TOXICITY." UKnowledge, 2018. https://uknowledge.uky.edu/toxicology_etds/22.
Full textLeung, Ho Man Homan. "Interactions of arbuscular mycorrhizal fungi with an arsenic hyperaccumulator plant (pteris vittata) on the uptake of arsenic." HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/945.
Full textCapri, Maria da Rosa. "Avaliação de elementos potencialmente tóxicos em tintas." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/46/46133/tde-05072016-112942/.
Full textThis work presents the results of the determination, using ICP OES, of the toxic and/or potentially toxic elements (AI, Cr, Ni, Cu, Cd, As, Co and Pb) in paints based in water or organic solvent. Sample digestion method were developed and compared using different acid mixtures in decomposition pumps, in microwave oven (focused and with cavity) and ash method. The digestion method using microwave oven with cavity allowed fast and efficient solubilization of ali tested types of paints, in inferior time to 35 mino The methodologies showed acceptable values for the majority of the elements using addition and recovery tests. The residues resulting of the digestion were analyzed by SEM-EDS and did not present the studied elements, checking the efficiency of the method. Mercury was determined using a Direct Mercury Analyzer (DMA) presenting values between 43.0 ± 4.5 and 188 ± 9 µg.kg-1, value considered low when compared to the Iimit of 100 mg.kg-1, established in the norm NBR 10004 for disposition of solid residues without special installations. The migration of the elements for the environment was studied afier the exposition of the paints to aggressor agents, Iike ultraviolet radiation and humidity, using a Weather-Ometer type chamber (accelerated aging). The evaluation of the results was performed by SEM-EDS and ICP-OES. The SEM micrographs showed changes on the polymer morphologies submitted to accelerated aging. The obtained results were not conclusive on the migration of elements because of the low mass ratio between the degraded and non-degraded samples. The proposed method for the evaluation by ICP-OES of paints and the disponibility of toxic and potentially toxic elements, based on the lixiviation of dry samples in controlled environment is described. Lixiviation results of AI, Cr, Ni, Cu, Cd, As, Co and Pb using several different removal agents and extraction times are presented. The results show that happens the migration of some elements for the studied solutions and that, among ali removal agents, the acid rain showed the highest lixiviation potential. that, among ali removal agents, the acid rain showed the highest lixiviation potential.
Johnson, Adam Nicholas. "Toxicological Comparison of Heavy Metal Salt and Semiconductor Nanoparticle Exposure in Zebrafish (Danio rerio)." Fogler Library, University of Maine, 2007. http://www.library.umaine.edu/theses/pdf/JohnsonAN2007.pdf.
Full textLi, Hui. "The role of arbuscular mycorrhizal fungi (AMF) on the tolerance and accumulation of arsenic in rice (Oryza sativa L.)." HKBU Institutional Repository, 2012. https://repository.hkbu.edu.hk/etd_ra/1409.
Full textParviz, Maryam. "Evaluation of Zinc Toxicity Using Neuronal Networks on Microelectrode Arrays: Response Quantification and Entry Pathway Analysis." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc3928/.
Full textChan, Wai Fung. "The roles of arbuscular mycorrhizal fungi in arsenic uptake and tolerance of upland rice." HKBU Institutional Repository, 2011. http://repository.hkbu.edu.hk/etd_ra/1257.
Full textHu, Junli. "Risk assessment and mycorrhizal remediation of cadmium contamination in vegetable farms around the Pearl River Delta, China." HKBU Institutional Repository, 2013. http://repository.hkbu.edu.hk/etd_ra/1484.
Full textEscorihuela, Martí Laura. "Computational characterisation of metal oxide nanoparticles for hazard screening and risk assessment." Doctoral thesis, Universitat Rovira i Virgili, 2019. http://hdl.handle.net/10803/669615.
Full textLas propiedades intrínsecas de las nanopartículas de óxidos metálicos (MEO) NPs son el pilar fundamental de aplicaciones avanzadas tecnológicamente en áreas como electrónica, farmacia o medicina. En cambio, existe un importante vacío en cuanto cómo influyen sus propiedades físico-químicas y el riesgo que suponen para la salud humana, la evaluación de la toxicidad de los nanomateriales es un dura tarea que involucra múltiples condiciones experimentales. Los métodos computacionales, in-silico, teóricos y estadísticos, evalúan, determinan y predicen procesos o incluso propiedades de las sustancias. Además de la urgencia que existe legislativa para evaluar el riesgo que conllevan, existe un vacío en la literatura, dado que en los diferentes experimentos que se explican en la literatura tienen vacíos en la explicación de la metodología empleada o detalles experimentales, entonces no son útiles para la evaluación del riesgo. El método más popular computacional, es Density Functional theory (DFT), basado en la mecánica cuántica. En esta tesis se desarrolla un estricto estudio de los mejores métodos que permiten optimizar desde la energía del estado fundamental para superficies, nanotubos y nanopartículas esféricas. Para obtener valores más precisos para la determinación del band gap, se ha incrementado el nivel de teoría utilizando el DFT + U, finalmente para obtener valores para sistemas de 3000 átomos para la simulación de sistemas biológicos, se ha implementado el método DFTB de dinámica molecular, también utilizado para la evaluación de la solubilidad. Los resultados computacionales obtenidos por ZnO han sido prometedores, entonces se ha probado para el TiO2, demostrando la validez de la metodología ideada. Finalmente, los datos obtenidos se han utilizado para crear modelos de predicción de propiedades (band gap y solubilidad) para NPs más grandes y con estas poder generar modelo nano-QSAR ( Cantidad-eStructura-Acividad-Relación), donde se relacionan estas propiedades estudiadas con el nivel de toxicidad del MeO NP.
Given the intrinsic properties, metal oxide nanoparticles (MeO) NPs are the cornerstone of a wide range of technologically advanced applications in areas such as electronics, pharmacy or medicine. However, there is still an important knowledge gap regarding how size influences their physicochemical properties and the risk to human health. Toxicity assessment of NMs is a daunting task involving multiple testing conditions. Computed based methods, in silico methods, based on theoretical and statistical domain, evaluate, determine and predict processes or even substance properties. Furthermore, the legislation urgency for risk assessment exits given that the data for the environmental risk assessment found in literature is uncertain and present knowledge gaps, though is not useful for the risk assessment for nanoparticles. The most popular in silico method based on quantum mechanics for chemistry is Density Functional Theory (DFT). In this thesis we performed a strict and deep study of best methods to evaluate the band gap and the solubility of MeO NP. The use of periodical-DFT methods has allowed us to optimise the ground state energy for surfaces, nanotubes and spherical nanoparticles. To get more reliability for band gap determination, the exchange-correlation functional has been improved to DFT+U. After that, to reach to large systems up to 3000 atoms in order to simulate more realistic biological systems, we used DFTB methodology for band gap prediction; we also coupled DFTB with Molecular Dynamics to compute NP solubility. The computational results obtained with the methodology developed in this thesis for the ZnO case have been promising and, in order to make more robust the method employed, it has been tested for TiO2 too, showing an excellent efficiency in the results. Finally, the data obtained from the prediction models of band gap and solubility models have been used to create nano-QSAR (Quantity-Structure-Activity-Relationship) models.
Watanabe, Cláudia Hitomi. "Avaliação ecotoxicológica de metais/metalóides e interferentes endócrinos em frações de substâncias húmicas de diferentes tamanhos moleculares /." Sorocaba, 2015. http://hdl.handle.net/11449/124025.
Full textCoorientador: Renata Fracácio
Banca: Alessandra Emanuele Tonietto
Banca: Viviane Moschini Carlos
Resumo: No presente trabalho, ensaios de toxicidade com o metalóide arsênio, o metal cobalto e o contaminante emergente17β-estradiol foram estudados na presença e ausência das substâncias húmicas aquáticas (SHA) e suas frações de diferentes tamanhos moleculares (<5, 5-10; 10-30; 30-100 e >100 kDa), utilizando-se os organismos Ceriodaphnia dubia e Pseudokirchneriella subcapitata. Aos ensaios utilizando-se o organismo C. dubia, a influência das SHA em contato com o metal arsênio na redução da toxicidade por análise estatística aumentou a reprodução. Nas diferentes frações de SHA observou-se variação de toxicidade nas frações de tamanhos moleculares maiores, na seguinte ordem crescente de toxicidade: F1=F2