Academic literature on the topic 'Metabolic processes'

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Journal articles on the topic "Metabolic processes"

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Zemskov, Andrei M., Tatiyana A. Berezhnova, Veronika A. Zemskova, Kseniya S. Dyadina, Yana V. Kulintsova, and Anton V. Larin. "Immune-metabolic genesis of pathological processes." Research Results in Pharmacology 5, no. 4 (2019): 19–31. http://dx.doi.org/10.3897/rrpharmacology.5.38386.

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This article deals with metabolic-immune processes at rest and under stress conditions, which, in turn, results in the development of immune-dependent and immune-associated disorders. The article analyzes study results and conclusions of various literature sources and experimental data in healthy individuals and patients suffering from non-specific inflammatory lung diseases; purulent-inflammatory diseases and their combinations, primary and secondary progressive multiple sclerosis in the acute stage and remission. Research studies investigated the impact of the type, stage, combination of diseases on the parameters of the immunologic and metabolic statuses, as well as their correlations. The authors also analyzed metabolic effects of immunomodulators. Based on the analysis of the literature and own clinical and experimental data, the authors identified the ability of metabolic factors to regulate immunological processes. A correlative analysis of examination results of the patients with various diseases helped detect the unity of the immune-metabolic mechanisms of pathology. The data on the therapeutic effect of various modulators through differentiated biochemical chains and vice versa – the metabolic effect through immunological mechanisms –were analyzed in the study. Thus, one can testify that there is the phenomenon of a mediated effect of some immunocorrectors on the reactivity through metabolic chains. The fact that a number of modulators and metabolics can simultaneously affect the biochemical and immunological parameters of patients proved the above phenomenon. There was revealed a significant correlation interaction of the immune-metabolic parameters with various types of purulent-inflammatory diseases, which proves the formation of a single mechanism of pathology.
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Zemskov, Andrei M., Tatiyana A. Berezhnova, Veronika A. Zemskova, Kseniya S. Dyadina, Yana V. Kulintsova, and Anton V. Larin. "Immune-metabolic genesis of pathological processes." Research Results in Pharmacology 5, no. (4) (2019): 19–31. https://doi.org/10.3897/rrpharmacology.5.38386.

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This article deals with metabolic-immune processes at rest and under stress conditions, which, in turn, results in the development of immune-dependent and immune-associated disorders. The article analyzes study results and conclusions of various literature sources and experimental data in healthy individuals and patients suffering from non-specific inflammatory lung diseases; purulent-inflammatory diseases and their combinations, primary and secondary progressive multiple sclerosis in the acute stage and remission. Research studies investigated the impact of the type, stage, combination of diseases on the parameters of the immunologic and metabolic statuses, as well as their correlations. The authors also analyzed metabolic effects of immunomodulators. Based on the analysis of the literature and own clinical and experimental data, the authors identified the ability of metabolic factors to regulate immunological processes. A correlative analysis of examination results of the patients with various diseases helped detect the unity of the immune-metabolic mechanisms of pathology. The data on the therapeutic effect of various modulators through differentiated biochemical chains and vice versa – the metabolic effect through immunological mechanisms –were analyzed in the study. Thus, one can testify that there is the phenomenon of a mediated effect of some immunocorrectors on the reactivity through metabolic chains. The fact that a number of modulators and metabolics can simultaneously affect the biochemical and immunological parameters of patients proved the above phenomenon. There was revealed a significant correlation interaction of the immune-metabolic parameters with various types of purulent-inflammatory diseases, which proves the formation of a single mechanism of pathology.
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Shipman, Jason, Jeffrey Guy, and Naji N. Abumrad. "Repair of metabolic processes." Critical Care Medicine 31, Supplement (2003): S512—S517. http://dx.doi.org/10.1097/01.ccm.0000081547.31084.23.

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Gutfreund, H. "Control of metabolic processes." FEBS Letters 284, no. 1 (1991): 133. http://dx.doi.org/10.1016/0014-5793(91)80780-7.

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McHugh, Jessica. "Targeting autoimmune-specific metabolic processes." Nature Reviews Rheumatology 14, no. 12 (2018): 686. http://dx.doi.org/10.1038/s41584-018-0126-1.

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Sanchez, Sergio, and Arnold L. Demain. "Metabolic regulation of fermentation processes." Enzyme and Microbial Technology 31, no. 7 (2002): 895–906. http://dx.doi.org/10.1016/s0141-0229(02)00172-2.

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Vladimir M, Zemskov, Zemskov Andrey M, Pronko Konstantin N, et al. "Immuno-Metabolic Aspects of Pathological Processes." International Journal of Current Research and Review 13, no. 21 (2021): 07–13. http://dx.doi.org/10.31782/ijcrr.2021.132101.

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Татарчук, Т. Ф., Н. Ю. Педаченко, and З. Б. Хомінська. "Metabolic syndrome and hyperproliferative endometrial processes." Reproductive Endocrinology, no. 16 (July 11, 2014): 61. http://dx.doi.org/10.18370/2309-4117.2014.16.61-69.

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Heinrich, Reinhart, and Christine Reder. "Metabolic control analysis of relaxation processes." Journal of Theoretical Biology 151, no. 3 (1991): 343–50. http://dx.doi.org/10.1016/s0022-5193(05)80383-2.

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Iwatani, Shintaro, Yohei Yamada, and Yoshihiro Usuda. "Metabolic flux analysis in biotechnology processes." Biotechnology Letters 30, no. 5 (2008): 791–99. http://dx.doi.org/10.1007/s10529-008-9633-5.

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Dissertations / Theses on the topic "Metabolic processes"

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Finkel, Zoe Vanessa. "Diatoms, size and metabolic processes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ36438.pdf.

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Ford, Yves-Yannick. "Metabolic studies of transformed roots." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260120.

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Arnold, Anne. "Modeling photosynthesis and related metabolic processes : from detailed examination to consideration of the metabolic context." Phd thesis, Universität Potsdam, 2014. http://opus.kobv.de/ubp/volltexte/2014/7227/.

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Mathematical modeling of biological systems is a powerful tool to systematically investigate the functions of biological processes and their relationship with the environment. To obtain accurate and biologically interpretable predictions, a modeling framework has to be devised whose assumptions best approximate the examined scenario and which copes with the trade-off of complexity of the underlying mathematical description: with attention to detail or high coverage. Correspondingly, the system can be examined in detail on a smaller scale or in a simplified manner on a larger scale. In this thesis, the role of photosynthesis and its related biochemical processes in the context of plant metabolism was dissected by employing modeling approaches ranging from kinetic to stoichiometric models. The Calvin-Benson cycle, as primary pathway of carbon fixation in C3 plants, is the initial step for producing starch and sucrose, necessary for plant growth. Based on an integrative analysis for model ranking applied on the largest compendium of (kinetic) models for the Calvin-Benson cycle, those suitable for development of metabolic engineering strategies were identified. Driven by the question why starch rather than sucrose is the predominant transitory carbon storage in higher plants, the metabolic costs for their synthesis were examined. The incorporation of the maintenance costs for the involved enzymes provided a model-based support for the preference of starch as transitory carbon storage, by only exploiting the stoichiometry of synthesis pathways. Many photosynthetic organisms have to cope with processes which compete with carbon fixation, such as photorespiration whose impact on plant metabolism is still controversial. A systematic model-oriented review provided a detailed assessment for the role of this pathway in inhibiting the rate of carbon fixation, bridging carbon and nitrogen metabolism, shaping the C1 metabolism, and influencing redox signal transduction. The demand of understanding photosynthesis in its metabolic context calls for the examination of the related processes of the primary carbon metabolism. To this end, the Arabidopsis core model was assembled via a bottom-up approach. This large-scale model can be used to simulate photoautotrophic biomass production, as an indicator for plant growth, under so-called optimal, carbon-limiting and nitrogen-limiting growth conditions. Finally, the introduced model was employed to investigate the effects of the environment, in particular, nitrogen, carbon and energy sources, on the metabolic behavior. This resulted in a purely stoichiometry-based explanation for the experimental evidence for preferred simultaneous acquisition of nitrogen in both forms, as nitrate and ammonium, for optimal growth in various plant species. The findings presented in this thesis provide new insights into plant system's behavior, further support existing opinions for which mounting experimental evidences arise, and posit novel hypotheses for further directed large-scale experiments.<br>Mathematische Modellierung biologischer Systeme eröffnet die Möglichkeit systematisch die Funktionsweise biologischer Prozesse und ihrer Wechselwirkungen mit der Umgebung zu untersuchen. Um präzise und biologisch relevante Vorhersagen treffen zu können, muss eine Modellierungsstrategie konzipiert werden, deren Annahmen das untersuchte Szenario bestmöglichst widerspiegelt und die dem Trade-off der Komplexität der zugrunde liegenden mathematischen Beschreibung gerecht wird: Detailtreue gegenüber Größe. Dementsprechend kann das System detailliert, in kleinerem Umfang oder in vereinfachter Darstellung im größeren Maßstab untersucht werden. In dieser Arbeit wird mittels verschiedener Modellierungsansätze, wie kinetischen und stöchiometrischen Modellen, die Rolle der Photosynthese und damit zusammenhängender biochemischer Prozesse im Rahmen des Pflanzenstoffwechsels analysiert. Der Calvin-Benson-Zyklus, als primärer Stoffwechselweg der Kohlenstofffixierung in C3-Pflanzen, ist der erste Schritt der Stärke- und Saccharoseproduktion, welche maßgeblich für das Wachstum von Pflanzen sind. Basierend auf einer integrativen Analyse zur Modellklassifizierung wurden aus der größten bekannten Sammlung von (kinetischen) Modellen des Calvin-Benson-Zyklus diejenigen ermittelt, die für die Entwicklung von Metabolic-Engineering-Strategien geeignet sind. Angeregt von der Fragestellung warum Kohlenstoff transitorisch vorwiegend in Form von Stärke anstatt Saccharose gespeichert wird, wurden die metabolischen Kosten beider Syntheseprozesse genauer betrachtet. Die Einbeziehung der Bereitstellungskosten der beteiligten Enzyme stützt die Tatsache, dass bevorzugt Stärke als temporärer Kohlenstoffspeicher dient. Die entprechende Untersuchung erfolgte einzig auf Grundlage der Stöchiometrie der Synthesewege. In vielen photosynthetisch-aktiven Organismen findet zudem Photorespiration statt, die der Kohlenstofffixierung entgegenwirkt. Die genaue Bedeutung der Photorespiration für den Pflanzenmetabolismus ist noch umstritten. Eine detaillierte Einschätzung der Rolle dieses Stoffwechselweges bezüglich der Inhibierung der Kohlenstofffixierungsrate, der Verknüpfung von Kohlenstoff- und Stickstoffmetabolismus, der Ausprägung des C1-Stoffwechsels sowie die Einflussnahme auf die Signaltransduktion wurde in einer modell-basierten, kritischen Analyse vorgenommen. Um die Photosynthese in ihrem metabolischen Kontext verstehen zu können, ist die Betrachtung der angrenzenden Prozesse des primären Kohlenstoffmetabolismus unverzichtbar. Hierzu wurde in einem Bottom-up Ansatz das Arabidopsis core Modell entworfen, mittels dessen die Biomasseproduktion, als Indikator für Pflanzenwachtum, unter photoautotrophen Bedingungen simuliert werden kann. Neben sogenannten optimalen Wachstumsbedingungen kann dieses großangelegte Modell auch kohlenstoff- und stickstofflimitierende Umweltbedingungen simulieren. Abschließend wurde das vorgestellte Modell zur Untersuchung von Umwelteinflüssen auf das Stoffwechselverhalten herangezogen, im speziellen verschiedene Stickstoff-, Kohlenstoff- und Energiequellen. Diese auschließlich auf der Stöchiometrie basierende Analyse bietet eine Erklärung für die bevorzugte, gleichzeitige Aufnahme von Nitrat und Ammonium, wie sie in verschiedenen Spezies für optimales Wachstum experimentell beobachtet wurde. Die Resultate dieser Arbeit liefern neue Einsichten in das Verhalten von pflanzlichen Systemen, stützen existierende Ansichten, für die zunehmend experimentelle Hinweise vorhanden sind, und postulieren neue Hypothesen für weiterführende großangelegte Experimente.
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Acerenza, Luis. "Studies on the control of time-dependent metabolic processes." Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/14242.

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Sensitivity analysis studies how changes in the parameters affect the system's variables. Its application to metabolic systems (Metabolic Control Analysis, MCA) was traditionally developed under certain assumptions:i) the steady state is stable (the effect on the steady state values only is studied).ii) each reaction is catalyzed by one enzyme, the rates being proportional to the corresponding enzyme concentration.iii) the parameters are changed by a small (strictly speaking infinitesimal) amount. In the present work MCA is extended to deal with the instantaneous values of time-dependent metabolite concentrations and fluxes. Their summation and connectivity relationships are derived. In some cases it is more convenient to characterize the time courses by time-invariant variables (such as period and amplitude in oscillating systems). Summation relationships for time-invariant variables are also derived. Stability analysis shows that a linear chain of four enzyme-catalized reactions, where the third metabolite is a negative effector of the first enzyme constitutes a 'minimal' oscillator. The model is used to gain insight into the control of oscillations. The control exerted by enzyme concentrations and other parameters that are not proportional to the rate is appropriately described by parameter-unspecified coefficients (C<SUB>v</SUB>). A proof of the theorems of steady-state MCA in terms of C<SUB>v</SUB> is given. By a similar procedure an attempt is made to derive the theorems in terms of C<SUB>v</SUB> for time-dependent systems, which is only successful for the particular case of constant π-matrix. The effect that a simultaneous change in all the enzyme concentrations by the same factor α (Coordinate-Control Operation. CCO) has on the variables of time-dependent metabolic systems is investigated. This factor α can have any arbitrary large value. The metabolic variables are classified according to the relationships they fulfil when the CCO is applied. A method is given to test these relationships in experimental systems and quantify deviations from the predicted behaviour.
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Li, Yanjun. "COMPUTATIONAL MODELING OF IN VIVO METABOLIC PROCESSES IN SKELETAL MUSCLE." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1283473428.

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Cairns, Andrew G. "Design and synthesis of small molecule probes for metabolic processes." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4897/.

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Synthesis of a photoactivated uncoupler I was completed and subsequently used by collaborators to demonstrate mitochondria uptake. The synthesis of a ratiometric, targetable calcium sensor was completed up to intermediate II (9 steps), alongside a thiohydantoin heterocycle III synthesised in 5 steps. A co-worker has subsequently completed the probe synthesis based on this route, with the resulting probe showing good binding and optical responses in testing. Numerous routes to 5,6-disubstituted phenanthridinium salts were investigated towards the synthesis of a mitochondrially targeted superoxide probe and hydroxylated standards. In the course of this work a novel cyclisation was developed based on intramolecular SNAr giving access to 9-benzyloxyphenanthridinium salt V. Rapid and high-yielding access to 5,6-disubstituted phenanthridinium salts IX was then achieved through forming benzophenones VIII via Suzuki coupling and converting these to imines with the alkylamine. The nitrogen atom of the imine then undergoes cyclisation onto the aryl fluoride in an intramolecular SNAr upon heating. This transformation was shown to have good steric and electronic tolerance in the synthesis of 13 phenanthridinium analogues with 6 structural diversification points. Subsequent DFT calculations by a colleague showed this reaction proceeds in a concerted fashion and as such represents a considerable mechanistic novelty. Efforts towards a new probe for mitochondrial superoxide led to the synthesis of 3-tertbutyl-dihydrophenanthridine X, which does not intercalate into DNA upon oxidation. This concept was refined and lead to the development of neopentyl ethidium XI and the targeted analogue MitoBNH XII and its deuterated analogue XIII.
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Soeprijanto. "Study of phosphorous released and removal under anaerobic and aerobic conditions." Thesis, University of Strathclyde, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249057.

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Barr, Sarah Marie. "Origins and consequences of altered metabolic processes in obese pregnant women." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/8827.

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Maternal obesity is an increasing concern in the obstetric population. It confers increased morbidity and mortality to the mother and offspring during pregnancy and delivery as well as potential long-term increase in risk of ill health to the offspring. There are currently few effective interventions and no pharmacological therapies. Potential mechanisms to account for ill health in obese non-pregnant individuals include excess inflammation, both systemically and within specific tissues such as adipose, as well as alterations in metabolic regulation including hyperglycaemia, reduced sensitivity to insulin and altered adipokine expression. In healthy pregnancy, there are significant adaptations to maternal metabolism, including the development of profound systemic insulin resistance. We hypothesize that there exists an interaction between the metabolic adaptations of pregnancy and those occurring in obesity which could provide a physiologically plausible mechanism which could contribute to the pathogenesis of adverse outcomes associated with obese pregnancies. In this thesis, we sought to understand and define the metabolic adaptations to pregnancy in severely obese women. Anthropometric characteristics are described in a longitudinal case-control study of apparently healthy obese (BMI > 40kg/m2) pregnant women. Systemic adipokine and pro- inflammatory cytokine profiles were measuring using ELISA. Indices of insulin sensitivity were assessed at three time points in pregnancy. In a cohort study of healthy pregnant women in the third trimester, transcript levels of adipokines and inflammatory cytokines in paired subcutaneous and omental adipose tissue biopsies were quantified and correlated these transcript levels with booking body mass index (BMI). Obese pregnant women gained less weight in pregnancy compared to lean women, but had significantly elevated fasting third trimester glucose, as well as elevated blood pressure and fasting insulin resistance throughout pregnancy. Fasting leptin was elevated throughout pregnancy in obese compared with lean pregnancy women; however, in the third trimester there was no correlation between adipose tissue leptin mRNA levels and BMI. Transcript levels of IL-6 were positively correlated with BMI in subcutaneous but not omental adipose tissue; no other positive correlations with BMI were shown. Hyperinsulinaemic euglycaemic clamps with concomitant use of stable isotope tracers were carried out in a case-control study of healthy obese pregnant women to characterise in detail whole body insulin sensitivity, endogenous glucose production and rate of lipolysis. In contrast to the original hypothesis, by the third trimester, there were few differences between lean and obese pregnant women in whole body glucose disposal (WGD) and endogenous glucose production. Compared with non-pregnant women, lean pregnant women demonstrated approximately 60% decrement in WGD; in contrast, obese non-pregnant women were already significantly insulin resistant but did not develop further insulin resistance in response to pregnancy. 3-Tesla (3T) Magnetic Resonance Imaging (MRI) and 1H-Magnetic Resonance Spectroscopy (1H-MRS)was used to assess abdominal fat distribution, hepatic and skeletal muscle lipid content in a case-control study of healthy pregnant women in the third trimester. As expected, obese pregnant women have greater adipose accumulation in both subcutaneous and intra-abdominal adipose depots and greater lipid accumulation in skeletal muscle. However, hepatic lipid content was low in both groups and there were no significant differences between lean and obese pregnant women. This was not expected as both groups are profoundly insulin resistant at this at this gestation, and in non-pregnant individuals, insulin resistance at this level would be expected to drive hepatic lipid accumulation, and may point to a pregnancyspecific hepato-protective mechanism. In conclusion, in this thesis, it has been shown that while obese women are insulin resistant with an adverse metabolic profile, that there does not appear to be the expected worsening of this profile in response to pregnancy and that by the end of pregnancy, lean women have a similar phenotype. Instead, while lean women are exposed to this environment only towards the end of pregnancy, obese women and their offspring are exposed throughout gestation, including key periods of fetal development in early pregnancy. This prolonged exposure may account for the excess pathologies in such pregnancies, potentially by exhausting what physiological reserve such women have pre-pregnancy. Potential therapies must therefore be optimally timed to improve the metabolic profile of obese women in early pregnancy, without hindering the required adaptations of the third trimester.
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Song, Yang. "Electrostatically controlled enzymatic reaction, metabolic processes and microbial generation of electric power." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1398685271.

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McWhorter, Todd Jason. "The integration of digestive, metabolic and osmoregulatory processes in nectar-eating birds." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/280198.

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Nectarivorous birds are represented by three major radiations: hummingbirds, honeyeaters, and sunbirds. These lineages share a number of convergent features in ecology, morphology, physiology, and behavior, and have served as important models in the study of foraging strategies and energetics. Because their diet is rich in water and sugar but poor in nitrogen and electrolytes, nectarivores provide a striking opportunity for evaluation of physiological constraints. My research emphasizes a novel aspect of the water-energy interaction: water overingestion in nectar-eating birds. The dual purpose of my dissertation research was to investigate the physiological mechanisms that allow nectar-eating birds to cope with exceedingly high ingestion of water and to elucidate the consequences of ingesting and processing large quantities of water for energy intake and for the maintenance of balance of important metabolites such as glucose. In nectar-eating birds, water overabundance in food has the potential effect of constraining energy procurement by overwhelming osmoregulatory processes and limiting digestive function. My research has allowed the development of an integrated quantitative description of gut and kidney function under the broad range of water loads and hydration conditions that birds can experience in the wild. Understanding limits to water processing will provide general insights into how animals are designed, on how aspects of design constrain their ecological performance, and into how aspects of design in one physiological system can impose limits on other systems. The osmoregulatory processes of nectar-eating birds highlight the relevance of understanding the impact that events taking place in the gut can have for feeding behavior, and renal and metabolic function. Adopting a broadly comparative approach to understanding the interaction between feeding behavior, digestion, and osmoregulation is pertinent because is unclear whether the many extreme physiological characteristics of hummingbirds that have traditionally been assumed to be associated with a nectar-feeding habit are shared by other nectar-eating birds. In my dissertation research I have begun to examine the similarities, and have found some important differences, in the responses of two major radiations of nectar-eating birds to their sugary and watery diets.
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Books on the topic "Metabolic processes"

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Cornish-Bowden, Athel, and María Luz Cárdenas, eds. Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2.

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NATO Advanced Research Workshop on Control of Metabolic Processes (1989 Lucca, Italy). Control of metabolic processes. Plenum Press, 1990.

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1962-, Häggblom Max M., and Bossert Ingeborg D. 1954-, eds. Dehalogenation: Microbial processes and environmental applications. Kluwer Academic Pub., 2003.

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Industriemuseum, Rheinisches, and Ludwig Galerie Schloss Oberhausen, eds. Stoffwechsel: Die Ruhrchemie in der Fotografie = Metabolic processes : Ruhrchemie in photography. Verlag Kettler, 2018.

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Colombo, Michael J. Nutrient enrichment, phytoplankton algal growth, and estimated rates of instream metabolic processes in the Quinebaug River basin, Connecticut, 2000-2001. U.S. Dept. of the Interior, U.S. Geological Survey, 2004.

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L, Kon O., International Union of Biochemistry. Committee on Symposia., and Satellite Symposium on Molecular and Protein Engineering (1986 : Singapore), eds. Integration and control of metabolic processes: Pure and applied aspects : the proceedings of the Fourth Federation of Asian and Oceanian Biochemists Congress and Satellite Symposium on Molecular and Protein Engineering, held in Singapore during November 30-December 5, 1986. Cambridge University Press, 1987.

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1944-, Sanchez-Esquivel Sergio, ed. Nitrogen source control of microbial processes. CRC Press, 1988.

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Gaylord, Carter Joseph, ed. Skeletal biomineralization: Patterns, processes, and evolutionary trends. Van Nostrand Reinhold, 1990.

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Engin, Atilla, and Ayse Basak Engin, eds. Tryptophan Metabolism: Implications for Biological Processes, Health and Disease. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-15630-9.

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Astrid, Sigel, and Sigel Helmut, eds. Manganese and its role in biological processes. Marcel Dekker, 2000.

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Book chapters on the topic "Metabolic processes"

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Ehrenfreund, Josef, David Kuhn, Nigel Armes, et al. "Metabolic Processes." In Modern Crop Protection Compounds. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527644179.ch31.

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Khanfer, Riyad, John Ryan, Howard Aizenstein, et al. "Metabolic Processes." In Encyclopedia of Behavioral Medicine. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101079.

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Atkinson, Daniel E. "What Should a Theory of Metabolic Control Offer to the Experimenter?" In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_1.

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Fell, David A., Herbert M. Sauro, and J. Rankin Small. "Control Coefficients and the Matrix Method." In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_10.

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Cascante, Marta, Rafael Franco, and Enric I. Canela. "Performance Indices in Metabolic Systems: a Criterion for Evaluating Effectiveness in Metabolic Regulation." In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_11.

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Canela, Enric I., Marta Cascante, and Rafael Franco. "Practical Determination of Control Coefficients in Metabolic Pathways." In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_12.

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Goldbeter, Albert, and Daniel E. Koshland. "Zero-order Ultrasensitivity in Interconvertible Enzyme Systems." In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_13.

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Chock, P. Boon, Sue Goo Rhee, and Earl R. Stadtman. "Metabolic Control by the Cyclic Cascade Mechanism: a Study of E. coli Glutamine Synthetase." In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_14.

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Cárdenas, María Luz, and Athel Cornish-Bowden. "Properties Needed for the Enzymes of an Interconvertible Cascade to Generate a Highly Sensitive Response." In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_15.

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Edstrom, Ronald D., Marilyn H. Meinke, Mary E. Gurnack, et al. "Regulation of Muscle Glycogenolysis." In Control of Metabolic Processes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9856-2_16.

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Conference papers on the topic "Metabolic processes"

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Alabbas, Faisal M., Brajendra Mishra, and David L. Olson. "Characterizations and Measurements on Biogenic Sludge Produced by Field SRB." In CORROSION 2015. NACE International, 2015. https://doi.org/10.5006/c2015-05489.

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Abstract Microbiologically influenced corrosion is not a distinct type of corrosion, but rather involves synergistic interaction of microorganisms with resulting biofilms and metabolic biogenic products that enhance corrosion processes. Therefore, it is important to obtain insights about the nature of the biogenic products resulting from microbial metabolic process. In this research, the biogenic products produced by sulfate reducing bacteria (SRB) cultivated from a sour oil field were characterized using X-ray photoelectron spectroscopy (XPS). Moreover, the zeta potential and magnetic susceptibility of SRB cells and biogenic products were evaluated using a microelectrophoretic apparatus and a magnetometer that is based on superconducting quantum interference methods, respectively. The results reveal that the biogenic sludge is mainly composed of different compounds of iron sulfides such as pyrrhotite and pyrite. Furthermore, it was found that the SRB consortium used in this investigation have negative surface charges of -53 mV as indicated by the zeta potential measurements and were able to generate paramagnetic sludge particles with an average calculated magnetic susceptibility of 1.4 x 10-6 m3/kg Fe. The implications of biogenic products physical and chemical characteristics on MIC will be presented.
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Licina, George J., and George Nekoksa. "The Influence of Water Chemistry and Biocide Additions on the Response of an On-line Biofilm Monitor." In CORROSION 1995. NACE International, 1995. https://doi.org/10.5006/c1995-95527.

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Abstract Microbiologically influenced corrosion (MIC) is a significant cause of degradation of piping and heat transfer surfaces in cooling water systems. The interaction between the metabolic processes of microorganisms attached to metallic surfaces and corrosion processes can lead to localized corrosion and rapid penetration of piping and heat exchanger tubes. On-line Monitoring of biofilm formation on Metallic Surfaces is a key both for automatic control equipment and for system operators so that mitigation activities can be initiated well before the structural integrity of piping or components is jeopardized. In addition, tracking of biofilm activity on line provides feedback useful for evaluating the effectiveness of biocide additions and optimizing the concentrations and addition schedules of biocides and other control chemicals. A probe has been developed to provide a method for determing the onset of biofilm formation on metal surfaces and tracking biofilm activity on line in a power plant or industrial environment; in fresh water and seawater environments. Experience with the system in a variety of water chemistries, and system responses to biofilm growth and subsequent destruction by biocide additions are described.
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Gao, Hongxia, Portonovo S. Ayyaswamy, and Paul Ducheyne. "Numerical Simulation of Global Diffusive Mass Transfer in a Rotating-Wall Vessel Bioreactor." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1312.

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Abstract The global diffusive mass transfer of different chemical species, specifically nutrition (glucose) and oxygen, in the fluid cell culture medium of the NASA designed Rotating-Wall Vessel (RWV) bioreactor has been numerically investigated. A finite difference method was employed to solve the governing equations for the species mass fraction fields. We have considered the 55 ml STLV and the 50 ml HARV as our domains of interest. The cell metabolic processes have been modeled as mass sinks absorbing oxygen and nutrition in the culture medium with time-dependent strengths. In one case studied, relative motion between the microcarrier and the fluid culture medium has been taken into account. The transient two-dimensional analysis employed here simulates the global mass diffusion process in the RWV. For the parameters considered here, the numerical results indicate that the HARV may be a better bioreactor for oxygen transport compared to the STLV.
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Pinto, Luiz André Lucas Teixeira, Vinícius Ribeiro Flores, Diogo Azevedo Coutinho, and Walter Barreiro Cravo Junior. "Impact of Different Carbon Sources on dsrAB Gene, a Major Concern for Oil and Gas Industries." In CONFERENCE 2024. AMPP, 2024. https://doi.org/10.5006/c2024-20602.

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Abstract Corrosion induced by microorganisms is an already known fact that affects, among other heavy industries, the oil and gas sector. Its understanding and deep knowledge can avoid material and physical damage to those involved in the related processes. Molecular tools may help to mitigate these possible damages; however, studies are needed to understand molecular mechanisms involving microbial activity, especially the transcription of important enzymes such as sulfite reductase (dsrAB) which may be involved in the corrosive process. mRNA extraction and cDNA synthesis were performed to quantify gene expression. Also, the enzyme production quantification by molecular techniques and H2S analysis were conducted to check dissolved gas concentration through potentiometric titration. It was possible to infer that availability of carbon sources and its complexity may increase bacterial metabolic activity, especially in the presence of lactate that, in this study, showed an increase in gene expression and H2S production compared to a variety of carbon sources and a control sample.
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Crista, Laura, Florin Crista, Isidora Radulov, Alina Lato, and Adina Berbecea. "ASSESSMENT OF THE IMPACT OF COMPLEX FOLIAR FERTILIZERS ON CORN (ZEA MAYS L.) PRODUCTIVITY." In 24th SGEM International Multidisciplinary Scientific GeoConference 2024. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024v/3.2/s12.25.

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This study investigates the effects of foliar fertilization (FF) on the yield and quality of corn grains, utilizing Principal Component Analysis (PCA) to optimize foliar treatment applications. The PCA approach enabled the identification of the most effective FF formulation for enhancing grain production and quality. The experiments were conducted in 2022 and 2023 at the university's experimental field, evaluating seven treatment variants, each with distinct chemical compositions labelled from V1 to V7, along with a control group. FF applications were carried out during the 15-16 BBCH and 20-22 BBCH vegetative stages of corn, with application rates ranging from 2 to 6 L/ha, according to the product specifications. Foliar fertilization of corn can directly influence the nutritional composition and quality of grains, affecting key components such as proteins, lipids, carbohydrates, fibers, and minerals. By applying nutrients directly to the leaves, this method can stimulate essential metabolic processes, leading to an improved nutritional profile of the grains. The FF treatments showed significant improvements in both the yield and quality of corn grains, as assessed through quality indicators such as moisture content, protein levels, lipids, carbohydrates, fibers, and minerals.
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Pang, Xin. "A Carbon Nanotube Based Electrochemical Sensor for Sulfide Detection." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-11628.

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Abstract Microbiologically influenced corrosion (MIC) is considered one of the major causes of oil and gas pipeline failures, costing billions of dollars annually. Despite the increasing research attention attracted to this area, in-situ detection and monitoring of MIC in real time has presented difficulties, due to the complexity of the corrosion processes resulted, directly or indirectly, from the ever evolving metabolic activities of microorganisms. In this work, an amperometric electrochemical biosensor based on a conducting polymer and carbon nanotubes was developed for detection and monitoring of hydrogen sulfide that can be generated by sulfate reducing bacteria, the main culprits of MIC. The single-walled carbon nanotubes (SWCNTs) are functionalized by a conductive polymer ‒ a polythiophene derivative, which enables the formation of carbon nanotube-polymer nanocomposite sensing layer with enhanced signal transduction capability. A cross-linking agent in optimized dosage was used to improve the water stability of the sensing layer without compromising its electric conductivity. Fast detection of sulfide was achieved with good sensitivity, attributed to the large active surface area of carbon nanotubes and excellent conductivity of the nanocomposite sensing layer. The sensor developed paved the way for further development of online sensors for monitoring MIC.
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Rodin, Vladimir B., Svetlana K. Zhigletsova, Nadezda A. Zhirkova, et al. "Altering Enviromental Composition as a Potential Method for Reversing Microbiologically Influenced Corrosion." In CORROSION 2005. NACE International, 2005. https://doi.org/10.5006/c2005-05498.

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Abstract The dynamics of corrosion losses caused by biofilms after changing culture conditions was investigated. Mild steel coupons were kept in the presence of biofilm generated by natural microbial micro-environment isolated from oil-processing waters. In addition to oil-oxidizing aerobes, the biofilm comprised sulphate-reducing bacteria. During formation of biofilm in glucose-mineral medium with peptone (GMP), corrosion losses increased vs control. The decrease of losses vs control was observed after transferring coupons carrying this biofilm into enriched with peptone Luria-Bertani medium (LB). During formation of biofilm in LB medium, corrosion losses decreased vs control. The increase of losses vs control was observed after transferring coupons with this biofilm into glucose-mineral medium. The high level of corrosion losses under intensive aeration conditions was registered. As soon as coupons with the biofilms were transferred into microaerophilic conditions, corrosion losses reduced sharply. Thus, it was confirmed that the subdivision of microorganisms into destructors and protectors is arbitrary. Results conclude that due to their combined metabolic activity, biofilms of natural microbial assemblages promptly respond to environmental factors, thereby either stimulating or inhibiting corrosion processes. This provides new opportunities for developing a promising approach to control MIC.
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Johnson, Richard. "Sequencing the Oil Field Microbiome – Can Metagenomics Help Combat MIC?" In CORROSION 2015. NACE International, 2015. https://doi.org/10.5006/c2015-05738.

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Abstract Corrosion costs between 1–5% of global gross domestic product annually. Microbiologically influenced corrosion is believed to contribute to around 20% of this. Due to the complexity of the microbial populations involved, the mechanisms of many of these processes are still poorly understood. Culture-based methods such as most probable number technique (MPN) and isolation only reveal a very small proportion of the microorganisms present, meaning that potentially problematic microorganisms are overlooked and not suitably targeted for mitigation. Due to revolutionary advances in DNA sequencing technologies, collectively known as next-generation sequencing (NGS), we are now able to sequence and identify many thousands of microorganisms in a single sample. By looking at the DNA sequences from these samples (metagenomics) we can identify what microorganisms are abundant (amplicon metagenomics), what the microorganisms are doing and even what they are capable of doing, by identifying their genomic and thus metabolic potential (through shotgun metagenomics). This wealth of information can be used to better understand specific corrosion mechanisms, target the responsible groups of microorganisms and ultimately predict their activities in order to control MIC. We present herein case studies where these new technologies have been used, which have enabled targeted mitigation strategies to minimize the impact that microorganisms have in the oil and gas industry.
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Hoffmann, Heike, Carol Devine, and Stephen Maxwell. "Application of Molecular Microbiology Techniques as Tools for Monitoring Oil Field Bacteria." In CORROSION 2007. NACE International, 2007. https://doi.org/10.5006/c2007-07508.

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Abstract For the past forty years, the oil industry has relied on two recommended standard practices (API RP-38 and NACE TM0194), which provide guidance on how field samples should be collected, analysed and results interpreted. Both documents highlight the enumeration of viable bacteria by culture techniques as the standard method for routine monitoring and anomaly investigation. API RP-38 has now been withdrawn. Within the appendices of TM0194 the possible availability of molecular microbiology techniques is mentioned, but no detailed guidance or standard method for the application of any of the molecular tools is currently available. As the application of molecular tools in environmental microbiology is developing rapidly, it is clear that a wide range of analyses are now available as potential tools to at last reveal ‘mysteries’ such as the complex metabolic processes causing the problems of microbial influenced corrosion (MIC), persistence in the presence of biocides and the souring of reservoirs during seawater flooding. However, these methods must be applied with caution. Whilst they undoubtedly offer the potential of huge strides forward in our understanding of oil field bacteria communities, there are no ‘off the shelf’ solutions and standardised methods will ultimately be required if comparative data are to be generated across the industry. This paper presents a summary of the benefits and drawbacks of some of the most commonly quoted molecular microbiology techniques together (where available) with examples of their application to field samples.
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Scherbakova, D., and Nadezhda Yudina. "BUILDING METABOLIC NETWORKS." In CHALLENGING ISSUES IN SYSTEMS MODELING AND PROCESSES. FSBE Institution of Higher Education Voronezh State University of Forestry and Technologies named after G.F. Morozov, 2025. https://doi.org/10.58168/cismp2024_768-772.

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The article presents a description of the construction and implementation of a program that builds a graph (metabolic network) based on a given stoichiometric matrix. Metabolic networks play a key role in understanding cellular processes and developing new approaches in medical and biotechnological research. The main modeling methods include both qualitative and quantitative approaches, each of which has its own characteristics and applications.
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Reports on the topic "Metabolic processes"

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Aharoni, Asaph, Zhangjun Fei, Efraim Lewinsohn, Arthur Schaffer, and Yaakov Tadmor. System Approach to Understanding the Metabolic Diversity in Melon. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7593400.bard.

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Fruit quality is determined by numerous genetic factors that affect taste, aroma, ‎color, texture, nutritional value and shelf life. To unravel the genetic components ‎involved in the metabolic pathways behind these traits, the major goal of the project was to identify novel genes that are involved in, or that regulate, these pathways using correlation analysis between genotype, metabolite and gene expression data. The original and specific research objectives were: (1) Collection of replicated fruit from a population of 96 RI lines derived from parents distinguished by great diversity in fruit development and quality phenotypes, (2) Phenotypic and metabolic profiling of mature fruit from all 96 RI lines and their parents, (3) 454 pyrosequencing of cDNA representing mRNA of mature fruit from each line to facilitate gene expression analysis based on relative EST abundance, (4) Development of a database modeled after an existing database developed for tomato introgression lines (ILs) to facilitate online data analysis by members of this project and by researchers around the world. The main functions of the database will be to store and present metabolite and gene expression data so that correlations can be drawn between variation in target traits or metabolites across the RI population members and variation in gene expression to identify candidate genes which may impact phenotypic and chemical traits of interest, (5) Selection of RI lines for segregation and/or hybridization (crosses) analysis to ascertain whether or not genes associated with traits through gene expression/metabolite correlation analysis are indeed contributors to said traits. The overall research strategy was to utilize an available recombinant inbred population of melon (Cucumis melo L.) derived from phenotypically diverse parents and for which over 800 molecular markers have been mapped for the association of metabolic trait and gene expression QTLs. Transcriptomic data were obtained by high throughput sequencing using the Illumina platform instead of the originally planned 454 platform. The change was due to the fast advancement and proven advantages of the Illumina platform, as explained in the first annual scientific report. Metabolic data were collected using both targeted (sugars, organic acids, carotenoids) and non-targeted metabolomics analysis methodologies. Genes whose expression patterns were associated with variation of particular metabolites or fruit quality traits represent candidates for the molecular mechanisms that underlie them. Candidate genes that may encode enzymes catalyzingbiosynthetic steps in the production of volatile compounds of interest, downstream catabolic processes of aromatic amino acids and regulatory genes were selected and are in the process of functional analyses. Several of these are genes represent unanticipated effectors of compound accumulation that could not be identified using traditional approaches. According to the original plan, the Cucurbit Genomics Network (http://www.icugi.org/), developed through an earlier BARD project (IS-3333-02), was expanded to serve as a public portal for the extensive metabolomics and transcriptomic data resulting from the current project. Importantly, this database was also expanded to include genomic and metabolomic resources of all the cucurbit crops, including genomes of cucumber and watermelon, EST collections, genetic maps, metabolite data and additional information. In addition, the database provides tools enabling researchers to identify genes, the expression patterns of which correlate with traits of interest. The project has significantly expanded the existing EST resource for melon and provides new molecular tools for marker-assisted selection. This information will be opened to the public by the end of 2013, upon the first publication describing the transcriptomic and metabolomics resources developed through the project. In addition, well-characterized RI lines are available to enable targeted breeding for genes of interest. Segregation of the RI lines for specific metabolites of interest has been shown, demonstrating the utility in these lines and our new molecular and metabolic data as a basis for selection targeting specific flavor, quality, nutritional and/or defensive compounds. To summarize, all the specific goals of the project have been achieved and in many cases exceeded. Large scale trascriptomic and metabolomic resources have been developed for melon and will soon become available to the community. The usefulness of these has been validated. A number of novel genes involved in fruit ripening have been selected and are currently being functionally analyzed. We thus fully addressed our obligations to the project. In our view, however, the potential value of the project outcomes as ultimately manifested may be far greater than originally anticipated. The resources developed and expanded under this project, and the tools created for using them will enable us, and others, to continue to employ resulting data and discoveries in future studies with benefits both in basic and applied agricultural - scientific research.
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Thomas, Helmuth. ALKOR Scientific Cruise Report The Ocean's Alkalinity - Connecting geological and metabolic processes and time-scales: mechanisms and magnitude of metabolic alkalinity generation in the North Sea Cruise No. AL557. GEOMAR, 2022. http://dx.doi.org/10.3289/cr_al557.

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Corscadden, Louise, and Anjali Singh. Metabolism And Measurable Metabolic Parameters. ConductScience, 2022. http://dx.doi.org/10.55157/me20221213.

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Metabolism is the sum of chemical reactions involved in sustaining the life of organisms.[1] It constantly provides your body with the energy to perform essential functions. The process is categorized into two groups:[2] Catabolism: It’s the process of breaking down molecules to obtain energy. For example, converting glucose to pyruvate by cellular respiration. Anabolism: It’s the process of synthesis of compounds required to run the metabolic process of the organisms. For example, carbohydrates, proteins, lipids, and nucleic acids.[2] Metabolism is affected by a range of factors, such as age, sex, muscle mass, body size, and physical activity affect metabolism or BMR (the basal metabolic rate). By definition, BMR is the minimum amount of calories your body requires to function at rest.[2] Now, you have a rough idea about the concept. But, you might wonder why you need to study it. What and how metabolic parameters are measured to determine the metabolism of the organism? Find the answer to all these questions in this article.
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Wong, S., C. Jeans, and M. Thelen. A Study of the Structure and Metabolic Processes of a Novel Membrane Cytochrome in an Extreme Microbial Community. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/894351.

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Aleksandrov, V. A., L. N. Shilova, A. V. Aleksandrov, et al. THE STUDY OF THE INFLUENCE OF ANGIOOPETIN-LIKE PROTEIN TYPE 4 ON THE INFLAMMATORY AND METABOLIC PROCESSES IN RHEUMATOID ARTHRITIS. Media Sphere, 2019. http://dx.doi.org/10.18411/2305-2198-2019-1-9-10.

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Hildebrand, Mark, Juergen Polle, and Michael Huesemann. A Systems Biology and Pond Culture-based Understanding and Improvement of Metabolic Processes Related to Productivity in Diverse Microalgal Classes for Viable Biofuel Production. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1458513.

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Blumwald, Eduardo, and Avi Sadka. Sugar and Acid Homeostasis in Citrus Fruit. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7697109.bard.

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Citrus fruit quality standards have been determined empirically, depending on species and on the particular growing regions. In general, the TSS (total soluble solids) to total acidity (TA) ratio determines whether citrus fruit can be marketed. Soluble sugars account for most of the TSS during harvest while TA is determined almost solely by the citric acid content, which reaches levels of 1-5% by weight in many cultivated varieties. Acid and sugar homeostasis in the fruit is critical for the management of existing cultivars, the development of new cultivars, the improvement of pre- and post-harvest strategies and the control of fruit quality and disorders. The current proposal (a continuation of a previous proposal) aimed at: (1) completing the citrus fruit proteome and metabolome, and establish a citrus fruit functional database, (2) further characterization of the control of fruit acidity by studying the regulation of key steps affecting citrate metabolism, and determine the fate of citrate during acid decline stage, and (3) Studying acid and sugar homeostasis in citrus fruits by characterizing transport mechanisms across membranes. These aims were completed as the following: (1) Our initial efforts were aimed at the characterization and identification of citric acid transporters in citrus juice cells. The identification of citrate transporters at the vacuole of the citrus juice cell indicated that the steady-state citrate cytosolic concentration and the action of the cytosolic aconitase were key elements in establishing the pH homeostat in the cell that regulates the metabolic shift towards carbon usage in the fruit during the later stages of fruit development. We focused on the action of aconitase, the enzyme mediating the metabolic use of citric acid in the cells, and identified processes that control carbon fluxes in developing citrus fruits that control the fruit acid load; (2) The regulation of aconitase, catalyzing a key step in citrate metabolism, was further characterized by using two inhibitors, citramalte and oxalomalte. These compounds significantly increased citrate content and reduced the enzyme’s activity. Metabolite profiling and changes of amino-acid metabolizing enzymes in oxalomalate- treated cells suggested that the increase in citrate, caused by aconitase inhibition, induces amino acid synthesis and the GABA shunt, in accordance with the suggested fate of citrate during the acid decline stage in citrus fruit. (3) We have placed a considerable amount of time on the development of a citrus fruit proteome that will serve to identify all of the proteins in the juice cells and will also serve as an aid to the genomics efforts of the citrus research community (validating the annotation of the fruit genes and the different ESTs). Initially, we identified more than 2,500 specific fruit proteins and were able to assign a function to more than 2,100 proteins (Katz et al., 2007). We have now developed a novel Differential Quantitative LC-MS/MS Proteomics Methodology for the identification and quantitation of key biochemical pathways in fruits (Katz et al., 2010) and applied this methodology to identify determinants of key traits for fruit quality (Katz et al., 2011). We built “biosynthesis maps” that will aid in defining key pathways associated with the development of key fruit quality traits. In addition, we constructed iCitrus (http://wiki.bioinformatics.ucdavis.edu/index.php/ICitrus), a “functional database” that is essentially a web interface to a look-up table that allows users to use functional annotations in the web to identify poorly annotated citrus proteins. This resource will serve as a tool for growers and field extension specialists.
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Burak, Leonid Ch, and Nataliya L. Ovsyannikova. Modern methods of storage and packaging of garden strawberries (Fragaria × ananassa Duch.) (review). Contemporary horticulture, 2024. https://doi.org/10.12731/2312-6701-266171.

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Postharvest treatment of garden strawberries and the development of effective storage methods are crucial to increase the shelf life and preserve its quality until consumption. Although some reviews on certain treatment technologies have been published, we have not found studies that considered and compared common and advanced methods of storing garden strawberries. Therefore, the goal of this study is to review modern postharvest methods of strawberry storage (Fragaria × ananassa Duch). The review includes reports published in English and Russian in 2014—2024. PubMed, Scopus, Web of Science, Elibrary and Google Scholar databases were used to search by keywords. 50 scientific publications have been studied. In the first part of our study, the metabolic and biochemistry processes that underlie the ripening process of strawberries are considered, the factors that cause spoilage of strawberry berries are analyzed, and modern methods of strawberry treatment are presented. The preservation of garden strawberries using radiation, light or heat treatment can prevent the development of microorganisms and increase the resistance of berries to diseases. However, these methods can have a negative impact on the nutritional value, color and taste of berries over time. Cold storage is the most commonly used method of storing garden strawberries after harvest throughout the supply chain. In addition to cold storage, post-harvest treatment methods, including thermal, cold plasma and chemical treatments, have been carefully studied and individually applied to further increase of the strawberry shelf life. These treatments help to prevent fungal infection, activate the metabolic protection system and improve the structural integrity of strawberry berries, thereby maintaining their quality over time, especially during cold storage. In addition to treatment methods, storage in a modified atmosphere, the application of active packaging and functional coatings have been recognized as effective ways to preserve the quality of berries and effectively prevent spoilage after harvest. In addition, the combined use of two or more of these methods has proven to be the most effective for improving the shelf life of garden strawberries. The analysis of the antifungal effectiveness of modern storage methods, study of the synergy between different methods and the development of solutions based on biopolymers represent a key path for future research.
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Starr, Robert C., Brennon R. Orr, M. Hope Lee, and Mark Delwiche. Final Project Report - Coupled Biogeochemical Process Evaluation for Conceptualizing Trichloriethylene Co-Metabolism: Co-Metabolic Enzyme Activity Probes and Modeling Co-Metabolism and Attenuation. Office of Scientific and Technical Information (OSTI), 2010. http://dx.doi.org/10.2172/972652.

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Grumet, R., J. Burger, Y. Tadmor, et al. Cucumis fruit surface biology: Genetic analysis of fruit exocarp features in melon (C. melo) and cucumber (C. sativus). United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134155.bard.

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The fruit surface (exocarp) is a unique tissue with multiple roles influencing fruit growth and development, disease susceptibility, crop yield, post-harvest treatments, shipping and storage quality, and food safety. Furthermore, highly visible exocarp traits are the consumer's first exposure to the fruit, serving to identify fruit type, variety, attractiveness, and market value. Cucurbit fruit, including the closely related Cucumis species, melon (C. melo) and cucumber (C. sativus), exhibit tremendous diversity for fruit surface properties that are not present in model species. In this project, we identified genetic factors influencing Cucumis fruit surface morphology with respect to important quality determinants such as exocarp and flesh color, cuticle deposition, and surface netting. We employed a combination of approaches including: genome-wide association studies (GWAS) utilizing an extensive melon population and the U.S. Plant Introduction (PI) collection for cucumber to identify genomic regions associated with natural variation in fruit surface traits; bulked segregant RNA-seq (BSR-seq) analysis of bi-parental F2:3 or RIL (recombinant inbred line) populations to genomic regions and candidate genes segregating for fruit surface traits; and comparison of syntenic genomic regions and identification of homologous candidate genes. Candidate genes were examined for sequence and/or expression differences during fruit development that correspond with phenotypic differences. Primary outcomes of the work included identification of candidate genes influencing cuticle deposition, epidermal cell structure, surface netting, and intensity of rind and flesh color. Parallel studies identified mutations within the cucumber and melon homologs of the transcription factor WIN1 (WAX INDUCER1) as a significant factor influencing these surface properties. Additional QTL (quantitative trait loci) were identified in both species, and candidate genes in melon include a novel beta-glucosidase involved in lignin production and an integral membrane protein potentially involved in cuticle metabolism. Genetic resources and biochemical approaches have been developed to study cuticle and wax deposition in both species: segregating populations of melon were developed and sequenced for bulked segregant analysis and samples collected for metabolic analysis; an isolation procedure was developed for lipid droplets from cucumber peel and metabolomic analyses have been initiated. Genetic studies in melon identified mutations in a candidate gene (APRR2), associated with light immature rind, and further indicated that this gene is also associated with color intensity of both mature rinds and flesh, making it a good target for breeding. GWAS studies utilizing the cucumber core diversity population are being performed to identify additional sources of variation for fruit surface properties, map QTL, and examine for synteny with melon. Collectively these studies identified genetic regions associated with important quality traits and contributed to our understanding of underlying biological processes associated with fruit surface development. Knowledge of genetic control of these characteristics can facilitate more efficient breeding for important fruit surface traits.
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