Relevant bibliographies by topics / Metabolic derangements

Academic literature on the topic 'Metabolic derangements'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Contents

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Metabolic derangements.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Metabolic derangements"

1

Allan, Russell, and Cristopher Foster. "Problem-Based Review: A patient with metabolic acidosis." Acute Medicine Journal 11, no. 4 (October 1, 2012): 251–56. http://dx.doi.org/10.52964/amja.0587.

Full text
Abstract:
Metabolic acidosis is a common metabolic derangement present in the acute medical patient. A thorough and structured investigative approach is required as there are many causes and management is reliant on identifying these. In particular calculation of the anion gap with correction for albumin level and use of the delta ratio can be helpful in complex cases especially in patients where a combination of metabolic derangements may be present.
APA, Harvard, Vancouver, ISO, and other styles
2

Gaboury, Cynthia L., Norman K. Hollenberg, Paul N. Hopkins, Roger Williams, and Gordon H. Williams. "Metabolic derangements in nonmodulating hypertension*." American Journal of Hypertension 8, no. 9 (September 1995): 870–75. http://dx.doi.org/10.1016/0895-7061(95)00160-q.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Pinder, Elizabeth M., Gurprit S. S. Atwal, Abraham A. Ayantunde, Sarah Khan, Mike Sokal, Tom McCulloch, and Simon L. Parsons. "Tumour Lysis Syndrome Occurring in a Patient with Metastatic Gastrointestinal Stromal Tumour Treated with Glivec (Imatinib Mesylate, Gleevec, STI571)." Sarcoma 2007 (2007): 1–5. http://dx.doi.org/10.1155/2007/82012.

Full text
Abstract:
Tumour lysis syndrome (TLS) is a rare side effect of chemotherapy for solid tumours. It describes the metabolic derangements following rapid and extensive tumour cell death following a good response to chemotherapy. Symptoms are those of metabolic derangement and renal failure. Treatment involves rehydration and correction of metabolic abnormalities. TLS should be considered in high risk groups. We report a case of TLS in a patient with metastatic gastrointestinal stromal tumour treated with imatinib mesylate. To our knowledge, this is the first reported case.
APA, Harvard, Vancouver, ISO, and other styles
4

Muoio, Deborah M., and Christopher B. Newgard. "Obesity-Related Derangements in Metabolic Regulation." Annual Review of Biochemistry 75, no. 1 (June 2006): 367–401. http://dx.doi.org/10.1146/annurev.biochem.75.103004.142512.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Puente-Maestu, Luis, Alberto Lázaro, and Blanca Humanes. "Metabolic derangements in COPD muscle dysfunction." Journal of Applied Physiology 114, no. 9 (May 1, 2013): 1282–90. http://dx.doi.org/10.1152/japplphysiol.00815.2012.

Full text
Abstract:
Mitochondrial muscle alterations are common in patients with chronic obstructive pulmonary disease (COPD) and manifest mainly as decreased oxidative capacity and excessive production of reactive oxygen species (ROS). The significant loss of oxidative capacity observed in the quadriceps of COPD patients is mainly due to reduced mitochondrial content in the fibers, a finding consistent with the characteristic loss of type I fibers observed in that muscle. Decreased oxidative capacity does not directly limit maximum performance; however, it is associated with increased lactate production at lower exercise intensity and reduced endurance. Since type I fiber atrophy does not occur in respiratory muscles, the loss of such fibers in the quadriceps could be to the result of disuse. In contrast, excessive production of ROS and oxidative stress are observed in both the respiratory muscles and the quadriceps of COPD patients. The causes of increased ROS production are not clear, and a number of different mechanisms can play a role. Several mitochondrial alterations in the quadriceps of COPD patients are similar to those observed in diabetic patients, thus suggesting a role for muscle alterations in this comorbidity. Amino acid metabolism is also altered. Expression of peroxisome proliferator-activated receptor-γ coactivator-1α mRNA is low in the quadriceps of COPD patients, which could also be a consequence of type I fiber loss; nevertheless, its response to exercise is not altered. Patterns of muscle cytochrome oxidase gene activation after training differ between COPD patients and healthy subjects, and the profile is consistent with hypoxic stress, even in nonhypoxic patients.
APA, Harvard, Vancouver, ISO, and other styles
6

Gebreegziabher, Yohannes, Amgad N. Makaryus, John N. Makaryus, and Samy I. McFarlane. "Heart failure: metabolic derangements and therapeutic rationale." Expert Review of Cardiovascular Therapy 5, no. 2 (March 2007): 331–43. http://dx.doi.org/10.1586/14779072.5.2.331.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Yadav, Hariom. "Whole Grains in Amelioration of Metabolic Derangements." Journal of Nutritional Health & Food Science 4, no. 4 (October 24, 2016): 1–11. http://dx.doi.org/10.15226/jnhfs.2016.00173.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Mazzoccoli, Gianluigi, Calogero Longhitano, and Manlio Vinciguerra. "Cardio-Hepatic Metabolic Derangements and Valproic Acid." Current Clinical Pharmacology 9, no. 2 (April 2014): 165–70. http://dx.doi.org/10.2174/1574884708999140101144839.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Baker, Susan S., Ellen Dwyer, and Patt Queen. "Metabolic Derangements in Children Requiring Parenteral Nutrition." Journal of Parenteral and Enteral Nutrition 10, no. 3 (May 1986): 279–81. http://dx.doi.org/10.1177/0148607186010003279.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Govindarajan, Gurushankar, Melvin R. Hayden, Shawna A. Cooper, Said Daibes Figueroa, Lixin Ma, Timothy J. Hoffman, Craig S. Stump, and James R. Sowers. "Metabolic Derangements in the Insulin‐Resistant Heart." American Journal of Geriatric Cardiology 15, no. 6 (November 2006): 102–6. http://dx.doi.org/10.1111/j.1559-4564.2006.05683.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Metabolic derangements"

1

Taveroff, Arlene. "Metabolic derangements following bone marrow transplantation : an integrated analysis." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74259.

Full text
Abstract:
Bone marrow transplantation (BMT) involves the use of maximal doses of chemotherapy and total body irradiation. As a result, even well-nourished patients exhibit negative nitrogen balance and hypoproteinemia in the post-transplant period, despite a high energy and protein intake from Total Parenteral Nutrition (TPN). The purpose of this research was to investigate the impact of cytotoxic therapy, with a view toward explaining and improving the response to nutritional support. Stool, urine and serum biochemistry were studied prospectively in 10 BMT patients. Analysis of stool revealed increased sodium and decreased potassium. Examination of serum electrolytes indicated hyponatremia and hyperkalemia. A significant decrease in nitrogen balance, serum albumin and net protein utilization immediately followed the disturbances in serum electrolytes; improvement began as serum sodium and potassium returned to normal. Thus, electrolyte imbalance may have reduced the capacity of cells to utilize nitrogen. Lowering the volume of TPN dramatically decreased serum electrolyte aberrations and improved nitrogen utilization.
APA, Harvard, Vancouver, ISO, and other styles
2

Fitzgerald, Danielle. "Pasture-associated metabolic derangements of horses: Pathogenesis and identification." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/134255/1/Danielle%20Maree_Fitzgerald_Thesis.pdf.

Full text
Abstract:
Equine metabolic syndrome (EMS) is a cluster of metabolic derangements that are important to manage in order to prevent associated diseases. The overarching purpose of this thesis was to examine the metabolic and gastrointestinal response to grazing in horses with EMS, and to evaluate the effectiveness of techniques currently used to identify EMS. The work showed that EMS occurs on a spectrum of severity and that the approach to diagnosis and management needs to account for the stage of disease. These outcomes will aid veterinary clinicians and horse owners in identifying EMS and provide new knowledge about disease management.
APA, Harvard, Vancouver, ISO, and other styles
3

Li, Shiying, and 李诗盈. "Maternal green tea epigallocatechin gallate supplementation counteracts high-fat diet-induced metabolic derangements in dams andtheir male offspring: a programming effect." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B47156132.

Full text
Abstract:
The overall objective of this thesis was to test the hypothesis that through developmental programming maternal overnutrition-induced metabolic derangements in the offspring could be offset by supplementing the maternal diet with green tea epigallocatechin gallate (GTEG). The obesogenic diet was a high-fat (HF, 30%) diet. Female Sprague-Dawley rats were fed the HF, low-fat (LF, 7%) or HF diet containing 0.75% or 1.0% GTEG (GT1, GT2) from before conception and throughout gestation and lactation. Both doses of GTEG significantly improved metabolic control of the HF-fed lactating dams. The weaned male pups received the HF, GT1 or GT2 diet forming 6 dam/pup groups: LF/HF, HF/HF, HF/GT1, HF/GT2, GT1/HF and GT2/HF. At wk 13 they had similar weight but insulin resistance index (IRI), serum non-esterified fatty acid (NEFA) and liver triglyceride of rats born to GTEG dams was 57, 23 and 26% lower and accompanied by improved gene/protein expressions related to lipid and glucose metabolism compared to HF/HF rats (P < 0.05). Although the HF/GT1 and HF/GT2 rats had lower serum NEFA, their serum insulin and IRI remained comparable with the HF/HF rats. To determine if there is a critical time period for the actions of GTEG, in the second experiment female rats were fed the LF, HF, or GT1 diet prior to conception and throughout gestation. During lactation, half of the dams had their diet switched from HF to GT1 and vice versa. Pups were weaned to the HF or LF diet, forming the LF/LF/LF, LF/LF/HF, HF/HF/LF, HF/HF/HF, HF/GT1/LF, HF/GT1/HF, GT1/GT1/LF, GT1/GT1/HF, GT1/HF/LF and GT1/HF/HF groups. Metabolic controls of dams given GT1 during gestation or lactation were improved compared with the HF/HF dams (P < 0.05). Three-way ANOVA revealed that 22 wk old offspring born to dams fed the HF diet during gestation had higher serum and muscle triglyceride (TG) concentration and lower ferric reducing ability of plasma (FRAP) (P < 0.05), all of which were reversed by supplementing GT1 to the gestational diet. Oral glucose tolerance at wk 15 was improved in those offspring born to dams given GT1 supplementation during lactation (P < 0.05). The increased serum NEFA concentration and IRI in offspring of dams fed the HF diet during gestation or lactation were reversible upon GT1 supplementation during either time period (P < 0.05). These rats (HF/GT1/HF, GT1/GT1/HF and GT1/HF/HF) had similar level of hepatic insulin receptor gene expression as well as protein abundance for muscle glucose transporter 4 and hepatic sterol regulatory element binding protein-1c but lower protein mass for hepatic glucose-6-phosphatase (P < 0.05) compared with the LF/LF/HF rats. Hence, maternal overnutrition-induced metabolic derangements in male offspring are reversible through supplementing GTEG to the maternal diet during gestation or lactation and this approach is more effective than giving GTEG to offspring born to overnourished mothers. Offspring metabolism could be programmed via manipulations of the maternal diet.
published_or_final_version
Biological Sciences
Doctoral
Doctor of Philosophy
APA, Harvard, Vancouver, ISO, and other styles
4

Romrig, Franziska [Verfasser], Melek Canan [Akademischer Betreuer] Arkan-Greten, Bernhard [Akademischer Betreuer] Küster, and Martin [Akademischer Betreuer] Klingenspor. "Metabolic Derangements in Pancreatic Cancer / Franziska Romrig. Gutachter: Bernhard Küster ; Melek Canan Arkan-Greten ; Martin Klingenspor. Betreuer: Melek Canan Arkan-Greten." München : Universitätsbibliothek der TU München, 2013. http://d-nb.info/1034952099/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Reinhart, Jennifer M. "Derangements of tonicity and implications for veterinary patients." Thesis, Kansas State University, 2014. http://hdl.handle.net/2097/19761.

Full text
Abstract:
Master of Science
Department of Clinical Sciences
Thomas Schermerhorn
Tonicity is property of a solution that is defined as the total effective (impermeable) osmole concentration that drives fluid movement across a semipermeable membrane via osmosis. Tonicity is related to but distinct from solution osmolality, which is a summation of all solute concentrations, regardless of the solute membrane permeability. In the mammalian body, tonicity is tightly regulated at both a cellular and systemic level; tonic derangements cause rapid change in cell and tissue volume leading to significant dysfunction. Input from the central nervous, circulatory, endocrine, gastrointestinal, and urinary systems are integral to osmoregulation, so many diseases in veterinary medicine are associated with tonicity disorders. However, because the homeostatic mechanisms that control tonicity overlap with those regulating electrolyte and acid-base balance as well as hydration and vascular volume, tonic consequences of disease can be difficult to isolate. Understanding of disease-associated changes in tonicity is further complicated by the fact that the tonic contributions of many solutes that accumulate in disease are unknown. Additionally, direct assessment of tonicity is difficult because tonicity is not just a physiochemical property, but it implies a physiologic effect. Thus, simple summation of osmole concentrations is an inadequate measurement of tonicity. The following report includes three studies investigating various aspects of tonicity as it applies to veterinary patients. Chapter 2 reports a study that examines the tonic effects of ketoacids and lactate using two different in vitro red blood cell assays. Results demonstrated that the ketoacids, beta-hydroxybutyrate and acetoacetate, behave as ineffective osmoles while the tonic behavior of lactate is variable, implying a more complex cellular handling of this anion. Two additional studies examine whether the mean corpuscular volume difference (dMCV) is a novel clinical marker for hypertonicity in dogs. Results of separate retrospective (Chapter 3) and prospective (Chapter 4) studies provide evidence that dMCV is a useful clinical marker for hypertonicity in dogs.
APA, Harvard, Vancouver, ISO, and other styles
6

Sturney, Sharon C. "Breath biomarkers of inflammation, infection and metabolic derangement in the intensive care unit." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/28648/.

Full text
Abstract:
The analysis of volatile organic compounds (VOCs) in breath may be a useful non-invasive tool in the Intensive Care Unit (ICU) to monitor metabolic and oxidative stress or diagnose pulmonary infection. Acetone is produced during starvation and metabolic stress, hydrogen sulphide (H2S) may be a marker of inflammation and infection and hydrogen cyanide (HCN) may also act as a marker of infection, particularly caused by Pseudomonas aeruginosa. Firstly, the effects on measured VOC concentrations of the breath collection equipment and storage were assessed. Sample humidity declined faster than any analyte. Sample losses of 21%, 25% and 24% for acetone, H2S and HCN, respectively, were seen as a result of being passed through the sampling apparatus. Over 90% of initial breath VOC concentrations were detectable after 90 min storage in Tedlar bags at 40°C. Secondly, a breath collection method for off-line analysis was validated in 20 mechanically ventilated patients in the ICU. The effect on VOC concentrations of breath sampling from two locations after two breathing manoeuvres was explored, revealing significantly higher analyte concentrations in samples from the airways than from a T-piece in the breathing circuit, and after tidal breathing compared to a recruitment-style breath. Practical difficulties were encountered using direct airway sampling and delivering recruitment style breaths; end-tidal breath sampling from the T-piece was simplest to perform and results equally reproducible. Breath samples from 26 healthy anaesthetised controls were used to validate a breath collection method in the operating theatre. The effects of altering anaesthesia machine settings on inspiratory and exhaled acetone concentrations were explored. A difference in median inspiratory, but not exhaled, acetone concentrations was observed between the anaesthesia machines (ADU Carestation 276 ppb, Aysis Carestation 131 ppb, p=0.0005). Closing the adjustable pressure limiting (APL) valve resulted in a reduction in exhaled acetone concentration, as did breath sampling distal to the circuit filter, due to dilution by dead space air. Median (range) breath concentrations for samples collected on the patient side of the circuit filter with the APL valve open (n=22): acetone 738 ppb (257–6594 ppb), H2S 1.00 ppb (0.71-2.49 ppb), HCN 0.82 ppb (0.60-1.51 ppb). Breath acetone concentration was related to plasma acetone (rs=0.80, p<0.0001) and beta-hydroxybutyrate concentrations (rs=0.55, p=0.0075). Finally, breath and blood samples were collected daily from 32 mechanically ventilated patients in the ICU with stress hyperglycaemia (n=11) and/or new pulmonary infiltrates on chest radiograph (n=28). Samples were collected over a median 3 days (1-8 days). Median (range) breath VOC concentrations of all samples collected: acetone 853 ppb (162–11,375 ppb), H2S 0.96 ppb (0.22-5.12 ppb), HCN 0.76 ppb (0.31-11.5 ppb). Median initial breath acetone concentration was higher than in anaesthetised controls (1451 ppb versus 812 ppb; p=0.038). There was a trend towards a reduction in breath acetone concentration over time. Relationships were seen between breath acetone and arterial acetone (rs=0.64, p<0.0001) and beta-hydroxybutyrate (rs=0.52, p<0.0001) concentrations. Several patients remained ketotic despite insulin therapy and normal, or near normal, arterial glucose concentrations. Inspired and exhaled H2S and HCN concentrations were not significantly different. Breath H2S and HCN concentrations could not be used to differentiate between patients with pneumonia and those with pulmonary infiltrates due to other conditions. In conclusion, losses due to the sampling apparatus were determined and linear over the range of concentrations tested. End-tidal breath sampling via the T-piece was the simplest technique, with reproducibility comparable to other methods. It was possible to replicate the breath sampling method in the operating theatre; pre-filter samples with inspiratory gas flow rate 6 L/min and APL valve open provided repeatable results avoiding rebreathing. There was no role for the use of breath H2S or HCN in the diagnosis or monitoring of pneumonia in critical illness. There was no relationship between breath acetone concentration and illness severity, however the utility of breath acetone in the modulation of insulin and feeding in critical illness merits further study.
APA, Harvard, Vancouver, ISO, and other styles
7

Abolghasemi, Armita. "Lipid mediators as regulators of lipid and energy metabolism during energy balance derangement in animal models." Doctoral thesis, Université Laval, 2020. http://hdl.handle.net/20.500.11794/67011.

Full text
Abstract:
Thèse en cotutelle : Université Laval, Québec, Canada et Università Studi Cagliari, Cagliari, Italie
Les facteurs environnementaux jouent un rôle clé dans le développement du syndrome métabolique et de l'obésité, qui sont maintenant de véritables épidémies soulevant des problèmes de santé publique. Les excès de graisse corporelle dans l'obésité et la perte de masse grasse et maigre dans les conditions de dénutrition ou d'anorexie mentale sont le résultat d'un déséquilibre énergétique. Par conséquent, le maintien de l'équilibre énergétique est crucial à la fois pour la prévention de l'obésité et pour le traitement de l'anorexie mentale et d'autres formes de dénutrition. Les signaux lipidiques tels que ceux médiés par les médiateurs des endocannabinoidomes sont profondément impliqués dans le contrôle du métabolisme énergétique. Dans cette thèse, au sein de deux projets différents, nous avons étudié comment différents facteurs environnementaux, y compris la restriction calorique, l'activité physique, la supplémentation en vitamine D et les médicaments antipsychotiques, peuvent conduire à une modification du métabolisme énergétique par la modulation de la signalisation des endocannabinoïdomes. Les résultats des travaux expérimentaux montrent comment les différentes conditions étudiées provoquent des changements dans les niveaux tissulaires du médiateur lipidique endocannabinoïdome ainsi que dans l'expression de leurs récepteurs et enzymes métaboliques, ce qui peut contribuer aux changements observés de la masse grasse corporelle et du métabolisme énergétique au sein des modèles. Nous concluons que les conditions étudiées peuvent provoquer des changements dans le bilan énergétique par altération de l'endocannabinoidome.
Environmental factors play a key role in the development of obesity-induced metabolic syndrome and obesity, which are now true epidemics raising public health concerns. Both excess body fat in obesity, and fat and lean mass loss in undernutrition conditions or anorexia nervosa, are the result of energy imbalance. Therefore, maintaining energy balance is crucial for both the prevention of obesity and the treatment of anorexia nervosa and other forms of undernutrition. Lipid signals such as those mediated by endocannabinoidome mediators are deeply involved in the control of energy metabolism. In this thesis, within two different projects, we studied how different environmental factors including calorie restriction, physical activity, vitamin D supplementation and antipsychotic drugs, may lead to energy metabolism modification through modulation of the endocannabinoidome signaling. The results of the experimental work show how the different studied conditions cause changes in the tissue levels of endocannabinoidome lipid mediator as well as in the expression of their receptors and metabolic enzymes, which may contribute to the observed changes in body fat mass and energy metabolism within the models. We conclude that the investigated conditions may cause changes in energy balance through alteration of the endocannabinoidome.
APA, Harvard, Vancouver, ISO, and other styles
8

"Lactate, a novel marker of disordered energy homeostasis in the metabolic derangements of obesity." THE JOHNS HOPKINS UNIVERSITY, 2009. http://pqdtopen.proquest.com/#viewpdf?dispub=3340035.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Yun, Chun-Ho, and 惲純和. "The Association among Metabolic Derangements, Atherosclerosis and Regional-Specific Visceral Fat Tissue Quantified by Multiple Detector Computed Tomography." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/07816281421667517219.

Full text
Abstract:
博士
國立陽明大學
生物醫學影像暨放射科學系
104
Excessive visceral adipose tissue accumulation is strongly associated with metabolic derangements including type 2 diabetes, hyperlipidemia, hypertension, cardiovascular disease risk and its factors. Visceral adipose tissue has been demonstrated to contribute to systemic inflammation and to be more relevant to unfavorable clinical outcomes. However, the most popular method, anthropometric measures of waist circumference for central obesity is relatively clinical convenient but may not precisely reflect the extent of visceral adipose tissue due to subcutaneous adipose tissue. Recently, multi-detector computed tomography (MDCT) provided a reliable and accurate method in assessing visceral adipose tissue. It is noninvasive and could quantify fat volume by semi-automatic segmentation technique to select all pixels in fat density of the region of interest. Current research studies of visceral adipose tissue quantified by MDCT mainly focused on pericardial fat (PCF) and thoracic peri-aortic fat (TAT). In 2008, the first article of PCF of MDCT published by Harvard medical school was from Framingham study. The definition of PCF is adipose tissue directly adjacently to myocardiaum and coronary arteries as well as confined by pericardium, isolated from other tissue and organs of thorax. TAT is adipose tissue surrounding a segment of thoracic descending aorta, not locally confined in thorax. Up-to-date, most published research studies discussed the relationship between these two regional visceral adipose tissue, coronary atherosclerosis and metabolic disease. However, is there strong association among different regional specific adipose tissue, pre-diabetes and carotid intimamedia thickness? Is the volume changes of PCF, TAT with aging? There is no definite conclusion now. In our study, in order to further assess the relationship between carotid atherosclerosis and regional specific adipose tissue, we created a novel way to define "peri-aortic root adipose fat" (PARF). We have measured the volume of adipose tissue surrounding a short segment of ascending aortic root of MDCT images and evaluated the influence of this regional specific adipose tissue on carotid morphology. The purposes in the present thesis study are: 1) To investigate the clinical significance, biological effects, and related cardiometabolic derangements of body-site specific visceral adipose tissue accumulation in a relatively healthy population. 2) To evaluate the degree of pericardial and thoracic peri-aortic adipose tissue, when quantified by multi-detector computed tomography, differs significantly in a normal, pre-diabetic, and overtly diabetic population. 3) To describe the relationship between a novel measurement of peri-arotic root fat and ultrasound measures of carotid artery remodeling. In our study, we have shown that age-related body-site specific adipose tissue accumulation may have distinct biological effects. Compared to other measures of adiposity, thoracic peri-aortic tissue is more closely associated with cardiometabolic risk and subclinical atherosclerosis in a relatively healthy population. Besides, pre-diabetic and diabetic subjects, compared to normoglycemia, were associated with significantly higher pericardial and peri-aortic adipose tissue burden. Visceral fat accumulation adjacent to the thoracic descending aorta seemed to exert a significant impact on insulin resistance and systemic inflammation. Peri-aortic root fat is associated with carotid intima-media thickness, even after adjustment for cardiometabolic risks, age and coronary atherosclerosis.
APA, Harvard, Vancouver, ISO, and other styles
10

HSUAN, CHIA, and 楊佳璇. "To investigate the role of vit D3 on metabolic derangement of patient with chronic kidney disease." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/73s9t9.

Full text
Abstract:
碩士
靜宜大學
食品營養研究所
98
The important relationship among serum Vitamin D3（25（OH）D3）、metabolic syndrome and insulin resistance in patient with chronic kidney disease（CKD）was investigated.It’s might be adjust the physiological metabolism and abnormalities of lipid metabolism are risk factor for the development of CKD.The aim of our study is to determine chronic kidney disease patients（CKD p’t） of serum Vitamin D3,whether abnormalities of lipid metabolism to cause the insulin resistence and the fat storeds. The experimental subject in 41 non-diabetes patient with CKD, tests for the time 12 weeks, by the questionnaire way collection clinical correlation data, illness medical history, 24hrs record the diet history、medicine use and anthropometric measurements, after the experiment ended, collects the urine and the hematologic analysis. Results showed that there was no significant relationship between sex, waistline, buttocks, body weight, BMI, smoke, activity, vitamins premix, sugar fasting, siastolic blood pressure and vitamin D3 concentration.Results also showed that Body weight、height、Hemoglobin、RBC、Vitamin D3 concentration、urine creatinine and the calories、carbohydrates、protein intake in the stage 3 of CKD p’t is higher than the stage 4、5 of of CKD p’t but the BUN、Creatine are lower than the stage 4、5 CKD p’t；Next, the Vitamin D3 concentration is greater than 25nmol/L,its Homa-IR、BUN、Creatine are to be lower than the concentration is smaller than 25 nmol/L,but the Vitamin D3 concentration is greater than 50 nmol/L,it’s blood sugar and the cholesterol is lower; In addition, we have also demonstrated that serum Vitamin D3 concentration and CKD are associated with insulin resistence and other components of the metabolic syndrom,such as triglyceride,and the CKD and insulin resistance is also related.In conclusion,we extrapolate that maintains the serum Vitamin D3 concentration In the non-diabetes CKD p’t to be possible to avoid the kidney function degree dropping、insulin resistance and abnormalities of lipid metabolism ,then further prevention metabolic syndrome.
APA, Harvard, Vancouver, ISO, and other styles

Books on the topic "Metabolic derangements"

1

Hormonal and Metabolic Derangements in Renal Failure. S. Karger AG (Switzerland), 1986.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Dierdorf, Stephen F. Introduction to Metabolic and Endocrine Diseases. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0024.

Full text
Abstract:
Patients may have metabolic and endocrine dysfunction that is primary and results in surgical pathology, or the surgical condition can produce metabolic changes that influence the administration of anesthesia. These disorders can vary with incidence of occurrence from commonly encountered situations such as hyperkalemia, to more rare disorders such as the porphyrias. Knowledge of the metabolic/endocrine derangements can lead to treatment that can be life-saving during the perioperative period. While it is important to periodically review the new developments in metabolism and endocrinology disorders, it is also helpful to review the long standing accepted treatments of the more unusual disorders. This will help to improve the application of appropriate treatment steps in the perioperative care of the patient.
APA, Harvard, Vancouver, ISO, and other styles
3

Cheng, Ning, Susan A. Masino, and Jong M. Rho. Metabolic Therapy for Autism Spectrum Disorder and Comorbidities. Edited by Jong M. Rho. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0014.

Full text
Abstract:
Autism spectrum disorder (ASD) is a heretogenous developmental disorder characterized by deficits in sociability and communication and by repetitive and/or restrictive behaviors. Currently, only comorbid manifestations can be alleviated (such as seizures and sleep disturbance) not core behavioral symptoms. Recent studies have increasingly implicated mitochondrial dysfunction as a cause of ASD. Mitochondria play an integral role in many cellular functions and are susceptible to many pathophysiological insults. Derangements in mitochondrial structure and function provide a scientific rationale for experimental therapeutics. Meanwhile, the high-fat, low-carbohydrate ketogenic diet (KD) has been shown to enhance mitochondrial function through a multiplicity of mechanisms. Reviewed herein is clinical and basic laboratory evidence for the use of metabolism-based therapies such as the KD in the treatment of ASD, as well as emerging comorbid models of epilepsy and autism. Future research directions aimed at validating such therapeutic approaches and identifying novel mechanistic targets are discussed.
APA, Harvard, Vancouver, ISO, and other styles
4

Jordan, Nerissa. Non-metastatic neurological manifestations of malignancy. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0238.

Full text
Abstract:
Neurological complications of systemic malignancy are frequent. They may reflect direct local effects of the tumour; CNS infection; side effects of chemotherapy or radiotherapy; nutritional or metabolic derangements; or a paraneoplastic syndrome. The paraneoplastic neurological syndromes are a group of disorders associated with a malignancy outside the nervous system. The pathophysiology is immune-mediated, with the tumour’s expression of neuronal proteins invoking antibody formation, which in turn results in neurological symptoms. This chapter will mainly focus on these syndromes.
APA, Harvard, Vancouver, ISO, and other styles
5

Franzese, Adriana, Enza Mozzillo, and Francesco Maria Rosanio. Glucose Metabolism Derangements in Pediatric Age. Cambridge Scholars Publishing, 2022.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Meier, Petra M., and Thomas O. Erb. Craniosynostosis and Apert Syndrome. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0021.

Full text
Abstract:
Apert syndrome is a complex, progressive multisystem condition of the craniosynostosis spectrum originating from a fibroblast growth factor receptor disorder. Multidisciplinary treatment teams may include craniofacial surgery, neurosurgery, otolaryngology, ophthalmology, oro-maxillofacial surgery, and pediatric intensive care. Secondary to midface hypoplasia, children often present with a compromised airway and have a high incidence of sleep disorders. Anesthetic considerations include difficult airway assessment, the presence of obstructive sleep apnea syndrome, and increased intracranial pressure. Extensive remodeling procedures can be associated with massive hemorrhage (e.g., venous sinus bleeding) and venous air embolism. Transfusion-related complications include coagulopathy, metabolic derangements, and primarily noninfectious hazards such as transfusion-related acute lung injury and transfusion-related immunomodulation. Multimodal blood management should focus on a combination of appropriate surgical techniques and blood conservation, along with guidance from point-of-care testing (including coagulation).
APA, Harvard, Vancouver, ISO, and other styles
7

Nelson, Jonathon, and Franklyn P. Cladis. Pediatric Liver Transplantation. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0038.

Full text
Abstract:
Liver transplantation has become a standard surgical treatment for pediatric patients with hepatic failure, tumors, and metabolic derangements. Liver transplantation in the pediatric population can be extremely challenging for the anesthesiologist due to multiple perioperative considerations. The first successful liver transplant was performed in a pediatric patient in the 1960s, and since then, there have been significant advances in immunosuppressant medications and preservation solutions which have led to improved survival. Nevertheless, the number of liver transplants continues to be limited by organ availability, although the pediatric donor pool has been increased by living related donors and split livers. The most common pediatric pathology that results in hepatic failure and transplantation is biliary atresia. This chapter covers the perioperative care of a pediatric patient undergoing a liver transplant, from the preoperative preparation to the intraoperative management, and discusses postoperative challenges which may be encountered while in the intensive care unit.
APA, Harvard, Vancouver, ISO, and other styles
8

Ruskin, David N. Metabolic Therapy and Pain. Edited by Detlev Boison. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0022.

Full text
Abstract:
Chronic pain is associated strongly with poor quality of life. Drug treatments for pain can be problematic; with the understanding that chronic pain syndromes often involve derangement of homeostasis, there is an increased interest in applying nonpharmacological metabolic therapies. This chapter surveys clinical and animal research into the effects of fasting, calorie restriction, ketogenic diet, and polyunsaturated fatty acid supplementation on pain. These dietary treatments can significantly ameliorate pain in inflammatory and neuropathic disorders. The choice among these treatments might depend on the specific pain syndrome and the tolerance of the patient for particular dietary modifications. Several possible mechanisms are discussed, some of which might be in common among these treatments, and some treatments might engage multiple mechanisms. Multiple mechanisms acting together could be ideal for restoring the disordered metabolism underlying some pain syndromes.
APA, Harvard, Vancouver, ISO, and other styles
9

Taljanovic, Mihra S., Imran M. Omar, Kevin B. Hoover, and Tyson S. Chadaz, eds. Musculoskeletal Imaging Volume 1. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190938161.001.0001.

Full text
Abstract:
This volume meets the needs of radiology residents to become adept at interpreting musculoskeletal (MSK) imaging studies. It does so by presenting core knowledge and fundamentals that must be learned to accurately and effectively interpret MSK studies by the trainee and non-specialist. The goal is to impart to residents, as well as to refresh for practitioners, essential facts in a concise and readable format so the reader becomes conversant with all imaging modalities used and the essentials of interpretation and technique. Other resources are at too high a level for the resident in training or contain far more information than a resident can easily assimilate during a rotation. The book is part of the Rotations in Radiology series for residents, which defines and encapsulates core knowledge for areas within Radiology, offering a guided, structured approach to imaging diagnosis. It contains sections on 10 key topics in MSK radiology: trauma; arthritis; tumors and tumor-like conditions; metabolic, hematopoietic, endocrine, and deposition diseases; infectious diseases; arthrography; internal derangements of the joints; congenital diseases; and ultrasound. Each section begins with an overview chapter, orienting the reader to the specific concerns and issues related to imaging that anatomic region or category of problem. Each clinical problem or diagnosis is concisely covered to provide a targeted discussion and highlight salient points. For each topic, concise chunks of text will review: definition; clinical features; anatomy and physiology; how to appraoch the image; what not to miss; differential diagnosis; common variants if pertinent; clinical issues; key points; high yield references.
APA, Harvard, Vancouver, ISO, and other styles
10

Taljanovic, Mihra S., Imran M. Omar, Kevin B. Hoover, and Tyson S. Chadaz, eds. Musculoskeletal Imaging Volume 2. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190938178.001.0001.

Full text
Abstract:
This volume meets the needs of radiology residents to become adept at interpreting musculoskeletal (MSK) imaging studies. It does so by presenting core knowledge and fundamentals that must be learned to accurately and effectively interpret MSK studies by the trainee and non-specialist. The goal is to impart to residents, as well as to refresh for practitioners, essential facts in a concise and readable format so the reader becomes conversant with all imaging modalities used and the essentials of interpretation and technique. Other resources are at too high a level for the resident in training or contain far more information than a resident can easily assimilate during a rotation. The book is part of the Rotations in Radiology series for residents, which defines and encapsulates core knowledge for areas within Radiology, offering a guided, structured approach to imaging diagnosis. It contains sections on 10 key topics in MSK radiology: trauma; arthritis; tumors and tumor-like conditions; metabolic, hematopoietic, endocrine, and deposition diseases; infectious diseases; arthrography; internal derangements of the joints; congenital diseases; and ultrasound. Each section begins with an overview chapter, orienting the reader to the specific concerns and issues related to imaging that anatomic region or category of problem. Each clinical problem or diagnosis is concisely covered to provide a targeted discussion and highlight salient points. For each topic, concise chunks of text will review: definition; clinical features; anatomy and physiology; how to appraoch the image; what not to miss; differential diagnosis; common variants if pertinent; clinical issues; key points; high yield references.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Metabolic derangements"

1

Jaworski, Nikki, and Ansgar Brambrink. "Electrolyte and Metabolic Derangements." In Handbook of Neurocritical Care, 13–35. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6842-5_2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Ciardella, F. "Effects of Nutritional Treatment on Hormonal and Metabolic Derangements of the Uremic Syndrome." In Nutritional Treatment of Chronic Renal Failure, 241–54. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-1583-4_27.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Gupta, Diptesh, and Madhukar Misra. "Metabolic Derangements Seen in Chronic Kidney Disease and End-Stage Renal Disease Patients." In Hemodialysis, 113–19. Basel: KARGER, 2011. http://dx.doi.org/10.1159/000327232.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

de la Monte, Suzanne M. "The Full Spectrum of Alzheimer’s Disease Is Rooted in Metabolic Derangements That Drive Type 3 Diabetes." In Advances in Experimental Medicine and Biology, 45–83. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-3540-2_4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Kawamata, Tatsuro, Y. Katayama, N. Tsuji, and H. Nishimoto. "Metabolic derangements in interstitial brain edema with preserved blood flow: selective vulnerability of the hippocampal CA3 region in rat hydrocephalus." In Brain Edema XII, 545–47. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-0651-8_111.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Leverve, X. M. "Derangements in Cellular Oxygen Metabolism." In Mechanisms of Organ Dysfunction in Critical Illness, 52–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56107-8_4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Morii, H., K. Matsumoto, G. Endo, S. Uematsu, T. Konishi, and K. Maekawa. "Clinical Presentation of Derangements of Mineral Metabolism." In Calcium in Internal Medicine, 3–12. London: Springer London, 2002. http://dx.doi.org/10.1007/978-1-4471-0667-8_1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Schiraldi, F., A. R. Derosa, and F. Paladino. "Metabolic Disorders and Electrolyte Derangement during Hypoperfusion Syndrome." In Anaesthesia, Pain, Intensive Care and Emergency Medicine - A.P.I.C.E., 691–96. Milano: Springer Milan, 1998. http://dx.doi.org/10.1007/978-88-470-2278-2_75.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Riley, P. A. "Derangements of Cellular Metabolism in The Pre-Malignant Syndrome." In Free Radicals: from Basic Science to Medicine, 199–205. Basel: Birkhäuser Basel, 1993. http://dx.doi.org/10.1007/978-3-0348-9116-5_17.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Yanagihara, Takehiko. "Metabolic Derangement and Cell Damage in Cerebral Ischemia with Emphasis on Protein and Nucleic Acid Metabolism." In Advances in Brain Resuscitation, 77–98. Tokyo: Springer Japan, 1991. http://dx.doi.org/10.1007/978-4-431-68538-8_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Metabolic derangements"

1

Fessel, Joshua P., Rizwan Hamid, Eric D. Austin, Yuji Tada, Bryan Wittmann, Anna Hemnes, and James West. "Metabolomic Analysis Reveals Widespread Metabolic Derangements In Pulmonary Arterial Hypertension." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6512.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Leduc-Gaudet, J. P., K. Miguez, J. Faitg, F. Eduardo Broering, O. Reynaud, D. Mayaki, L. Huck, M. Sandri, G. Gouspillou, and S. N. A. Hussain. "The Influence of Autophagy Inhibition on Sepsis-Induced Skeletal Muscle Wasting, Metabolic Derangements and Mortality." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2377.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Metabolic derangements' for particular source types:
Journal articles Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography