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Journal articles on the topic 'Mesoscale organisation'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

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1

Duncan, Anna L., Matthieu Chavent, Patrice Rassam, et al. "Nanoscale Protein Interactions Determine the Mesoscale Dynamic Organisation of Biomembranes." Biophysical Journal 114, no. 3 (2018): 391a. http://dx.doi.org/10.1016/j.bpj.2017.11.2163.

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Weijenborg, Chris, Petra Friederichs, and Andreas Hense. "Organisation of potential vorticity on the mesoscale during deep moist convection." Tellus A: Dynamic Meteorology and Oceanography 67, no. 1 (2015): 25705. http://dx.doi.org/10.3402/tellusa.v67.25705.

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Duncan, Anna L., Maximilian A. R. Bandurka, Matthieu G. Chavent, et al. "How Nanoscale Protein Interactions Determine the Mesoscale Dynamic Organisation of Membrane Proteins." Biophysical Journal 116, no. 3 (2019): 365a. http://dx.doi.org/10.1016/j.bpj.2018.11.1984.

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Mackay, Michael, Siyu Huo, and Marcus Kaiser. "Spatial organisation of the mesoscale connectome: A feature influencing synchrony and metastability of network dynamics." PLOS Computational Biology 19, no. 8 (2023): e1011349. http://dx.doi.org/10.1371/journal.pcbi.1011349.

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Significant research has investigated synchronisation in brain networks, but the bulk of this work has explored the contribution of brain networks at the macroscale. Here we explore the effects of changing network topology on functional dynamics in spatially constrained random networks representing mesoscale neocortex. We use the Kuramoto model to simulate network dynamics and explore synchronisation and critical dynamics of the system as a function of topology in randomly generated networks with a distance-related wiring probability and no preferential attachment term. We show networks which

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Lagouvardos, K., V. Kotroni, and E. Defer. "Synoptic environment related to rapid cyclogenesis in the Eastern Mediterranean." Advances in Geosciences 7 (February 14, 2006): 115–19. http://dx.doi.org/10.5194/adgeo-7-115-2006.

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Abstract. This paper presents first results on the investigation of the synoptic conditions that led to the rapid development of a low-pressure system over the Aegean Sea. Indeed, during the period 21–22 January 2004, a very deep cyclone was observed over the Aegean Sea with a minimum central pressure of ~972 hPa, a value which is among the lowest observed over the entire Mediterranean Sea during the last 40 years. The rapid development was associated with a two-trough system that, under the influence of a very intense upper-level jet, was merged in one and then acquired a negative tilting. Ad

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Duncan, Anna L., Maximillian A. R. Bandurka, Wanling Song та Mark S. P. Sansom. "Modelling the Dynamic Organisation of the β2-Adrenergic Receptor in Crowded Membranes: From the Nano to the Mesoscale". Biophysical Journal 118, № 3 (2020): 17a. http://dx.doi.org/10.1016/j.bpj.2019.11.277.

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Jansa, A., P. Alpert, P. Arbogast, et al. "MEDEX: a general overview." Natural Hazards and Earth System Sciences 14, no. 8 (2014): 1965–84. http://dx.doi.org/10.5194/nhess-14-1965-2014.

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Abstract. The general objective of the international MEDiterranean EXperiment (MEDEX) was the better understanding and forecasting of cyclones that produce high impact weather in the Mediterranean. This paper reviews the motivation and foundation of MEDEX, the gestation, history and organisation of the project, as well as the main products and scientific achievements obtained from it. MEDEX obtained the approval of World Meteorological Organisation (WMO) and can be considered as framed within other WMO actions, such as the ALPine EXperiment (ALPEX), the Mediterranean Cyclones Study Project (MC

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Callens, S. J. P., R. Burdis, M. Cihova, J. A. Kim, Q. Y. Lau, and M. M. Stevens. "GEOMETRIC CONTROL OF BONE TISSUE GROWTH AND ORGANIZATION." Orthopaedic Proceedings 106-B, SUPP_1 (2024): 65. http://dx.doi.org/10.1302/1358-992x.2024.1.065.

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Cells typically respond to a variety of geometrical cues in their environment, ranging from nanoscale surface topography to mesoscale surface curvature. The ability to control cellular organisation and fate by engineering the shape of the extracellular milieu offers exciting opportunities within tissue engineering. Despite great progress, however, many questions regarding geometry-driven tissue growth remain unanswered.Here, we combine mathematical surface design, high-resolution microfabrication, in vitro cell culture, and image-based characterization to study spatiotemporal cell patterning a

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Jansa, A., P. Alpert, P. Arbogast, et al. "MEDEX: a general overview." Natural Hazards and Earth System Sciences Discussions 2, no. 1 (2014): 535–80. http://dx.doi.org/10.5194/nhessd-2-535-2014.

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Abstract. The general objective of the international MEDiterranean EXperiment (MEDEX) was the better understanding and forecasting of cyclones that produce high impact weather in the Mediterranean. This paper reviews the motivation and foundation of MEDEX, the gestation, history and organisation of the project, as well as the main products and scientific achievements obtained from it. MEDEX obtained the approval of WMO and can be considered as framed within other WMO actions, such as ALPEX, MCP and, to certain extent, THORPEX and HyMeX. Through two phases (2000–2005 and 2006–2010) MEDEX has pr

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Siqueira, José Ricardo, and Valdo da Silva Marques. "Tracking and short-term forecasting of mesoscale convective cloud clusters over southeast Brazil using satellite infrared imagery." Journal of Southern Hemisphere Earth Systems Science 71, no. 1 (2021): 1. http://dx.doi.org/10.1071/es19050.

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This paper presents the tracking and short-term forecasting of mesoscale convective cloud clusters (CCs) that occurred over southeast Brazil and the adjacent Atlantic Ocean during 2009–17. These events produce intense rainfall and severe storms that impact agriculture, defence, hydroelectricity and offshore oil production. To identify, track and forecast CCs, the Geostationary Operational Environmental Satellite infrared imagery and the Forecasting and Tracking the Evolution of Cloud Clusters method are used. The forecast performance is investigated by applying statistical analyses between the

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Singh, Shweta, and Norbert Kalthoff. "Process Studies of the Impact of Land-Surface Resolution on Convective Precipitation Based on High-Resolution ICON Simulations." Meteorology 1, no. 3 (2022): 254–73. http://dx.doi.org/10.3390/meteorology1030017.

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This study investigated the relevant processes responsible for differences of convective precipitation caused by land-surface resolution. The simulations were performed with the ICOsahedral Nonhydrostatic model (ICON) with grid spacing of 156 m and Large Eddy Simulation physics. Regions of different orographic complexity, days with weak synoptic forcing and favourable convective conditions were selected. The resolution of land-surface properties (soil type, vegetation) and/or the orography was reduced from 156 to 5000 m. Analyses are based on backward trajectories (Lagrangian Analysis Tool (LA

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Masson, V., P. Le Moigne, E. Martin, et al. "The SURFEXv7.2 land and ocean surface platform for coupled or offline simulation of earth surface variables and fluxes." Geoscientific Model Development 6, no. 4 (2013): 929–60. http://dx.doi.org/10.5194/gmd-6-929-2013.

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Abstract. SURFEX is a new externalized land and ocean surface platform that describes the surface fluxes and the evolution of four types of surfaces: nature, town, inland water and ocean. It is mostly based on pre-existing, well-validated scientific models that are continuously improved. The motivation for the building of SURFEX is to use strictly identical scientific models in a high range of applications in order to mutualise the research and development efforts. SURFEX can be run in offline mode (0-D or 2-D runs) or in coupled mode (from mesoscale models to numerical weather prediction and

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Villiger, Leonie, Marina Dütsch, Sandrine Bony, et al. "Water isotopic characterisation of the cloud–circulation coupling in the North Atlantic trades – Part 1: A process-oriented evaluation of COSMO_iso simulations with EUREC⁴A observations." Atmospheric Chemistry and Physics 23, no. 23 (2023): 14643–72. http://dx.doi.org/10.5194/acp-23-14643-2023.

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Abstract. Naturally available, stable, and heavy water molecules such as HDO and H218O have a lower saturation vapour pressure than the most abundant light water molecule H216O; therefore, these heavy water molecules preferentially condense and rain out during cloud formation. Stable water isotope observations thus have the potential to provide information on cloud processes in the trade-wind region, in particular when combined with high-resolution model simulations. In order to evaluate this potential, nested COSMOiso (isotope-enabled Consortium for Small Scale Modelling; Steppeler et al., 20

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Poologaindran, A., R. Romero-Garcia, M. Hart, et al. "OS14.4.A The Neuroplastic Potential of the Human Brain before and After Glioma Surgery: Towards “Interventional Neurorehabilitation." Neuro-Oncology 23, Supplement_2 (2021): ii16. http://dx.doi.org/10.1093/neuonc/noab180.052.

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Abstract INTRODUCTION The human brain is a highly neuroplastic ‘complex’ network: it self-organises without a hard blueprint, adapts to evolving circumstances, and can withstand insults. However, similar to other naturally occurring networks, brain networks can only endure a finite amount of damage before cognitive processes are affected. In this study, we first sought to establish the brain networks governing domain-general cognition (DGC) in healthy individuals across the lifespan. We then sought to map, track, and potentially rehabilitate networks governing DGC through connectomics and non-

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Huntrieser, H., H. Schlager, M. Lichtenstern, et al. "NO<sub>x</sub> production by lightning in Hector: first airborne measurements during SCOUT-O3/ACTIVE." Atmospheric Chemistry and Physics Discussions 9, no. 4 (2009): 14361–451. http://dx.doi.org/10.5194/acpd-9-14361-2009.

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Abstract. During the SCOUT-O3/ACTIVE field phase in November–December 2005 airborne in situ measurements were performed inside and in the vicinity of thunderstorms over northern Australia with several research aircraft (German Falcon, Russian M55 Geophysica, and British Dornier-228). Here a case study from 19 November is presented in large detail on the basis of airborne trace gas measurements (NO, NOy, CO, O3) and stroke measurements from the German LIghtning Location NETwork (LINET), set up in the vicinity of Darwin during the field campaign. The anvil outflow from three different types of t

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Huntrieser, H., H. Schlager, M. Lichtenstern, et al. "NO<sub>x</sub> production by lightning in Hector: first airborne measurements during SCOUT-O3/ACTIVE." Atmospheric Chemistry and Physics 9, no. 21 (2009): 8377–412. http://dx.doi.org/10.5194/acp-9-8377-2009.

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Abstract. During the SCOUT-O3/ACTIVE field phase in November–December 2005, airborne in situ measurements were performed inside and in the vicinity of thunderstorms over northern Australia with several research aircraft (German Falcon, Russian M55 Geophysica, and British Dornier-228. Here a case study from 19 November is presented in detail on the basis of airborne trace gas measurements (NO, NOy, CO, O3) and stroke measurements from the German LIghtning Location NETwork (LINET), set up in the vicinity of Darwin during the field campaign. The anvil outflow from three different types of thunder

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17

Janssens, M., F. Jansson, P. Alinaghi, F. Glassmeier, and A. P. Siebesma. "Symmetry in Mesoscale Circulations Explains Weak Impact of Trade Cumulus Self‐Organization on the Radiation Budget in Large‐Eddy Simulations." Geophysical Research Letters 52, no. 3 (2025). https://doi.org/10.1029/2024gl112288.

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AbstractWe investigate if mesoscale self‐organisation of trade cumuli in 150 km‐domain large‐eddy simulations modifies the top‐of‐atmosphere radiation budget relative to 10 km‐domain simulations, across 77 characteristic, idealized environments. In large domains, self‐generated mesoscale circulations produce fewer, larger and deeper clouds, raising the cloud albedo. Yet they also precipitate more than small‐domain cumuli, drying and warming the cloud layer, and reducing cloud cover. Consequently, large domains cool slightly less through the shortwave cloud‐radiative effect, and slightly more t

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18

O'Malley, Brendan, David J. Moore, Massimo Noro, et al. "Towards a Mechanical Model of Skin: Insights into Stratum Corneum Mechanical Properties from Hierarchical Models of Lipid Organisation." MRS Proceedings 844 (2004). http://dx.doi.org/10.1557/proc-844-y5.7.

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ABSTRACTThe stratum corneum (SC), the outermost layer of the skin, provides the body with a physiologically essential barrier to unregulated water loss and the influx of exogenous substances. Furthermore, the 10–20 micron thick SC, composed of overlapping protein-rich corneocytes surrounded by a heterogeneous multilamellar lipid matrix, displays tremendous mechanical cohesion and thermal integrity. To understand the contribution of these components to SC mechanical properties requires building a complete mechanical model of the skin. In this study we focus on modelling the hierarchical microst

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19

Chavent, Matthieu, Anna L. Duncan, Patrice Rassam, et al. "How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins." Nature Communications 9, no. 1 (2018). http://dx.doi.org/10.1038/s41467-018-05255-9.

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20

Brient, Florent, Fleur Couvreux, Catherine Rio, and Rachel Honnert. "Coherent subsiding structures in large eddy simulations of atmospheric boundary layers." Quarterly Journal of the Royal Meteorological Society, November 21, 2023. http://dx.doi.org/10.1002/qj.4625.

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AbstractCoherent structures are characterized in high‐resolution simulations of three atmospheric boundary layers: dry convection, marine cumulus, and stratocumulus. Based on radioactive‐decaying tracers emitted at different altitudes (surface, top of well‐mixed layer, and cloud top), a object‐oriented methodology allows individual characterization of coherent tridimensional plumes within the flow.Each boundary layer shows updraft structures surrounded by subsiding shells that have similar thermodynamical characteristics. Well‐mixed downdrafts are located relatively close to updrafts and entra

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21

Vedechkina, Maria, Duncan E. Astle, and Joni Holmes. "Dimensions of early life adversity and their associations with functional brain organisation." Imaging Neuroscience, 2024. http://dx.doi.org/10.1162/imag_a_00145.

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Abstract Early life adversity is associated with differences in brain function and an elevated risk for poor mental health. Using data from children aged 10 (N=5,798) from the ABCD cohort we investigated how adversity relates to functional brain organisation using a network neuroscience approach. We derived four data-driven categories of adversity by fitting a mixed graphical model: household/community instability, physical/sexual abuse, parental neglect, and financial difficulties. Analyses revealed that multiple forms of adversity were associated with reduced clustering and increased assorta

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Head, Louise C., Claire Doré, Ryan R. Keogh, et al. "Spontaneous self-constraint in active nematic flows." Nature Physics, January 18, 2024. http://dx.doi.org/10.1038/s41567-023-02336-5.

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AbstractActive processes drive biological dynamics across various scales and include subcellular cytoskeletal remodelling, tissue development in embryogenesis and the population-level expansion of bacterial colonies. In each of these, biological functionality requires collective flows to occur while self-organised structures are protected. However, the mechanisms by which active flows can spontaneously constrain their dynamics to preserve structure are not known. Here, by studying collective flows and defect dynamics in active nematic films, we demonstrate the existence of a self-constraint, n

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Pryor, Kenneth, David L. A. Flack, David Smart, and Sarah Horton. "A study of the 23 October 2022 southern England damaging MCS." Weather, January 24, 2025. https://doi.org/10.1002/wea.7669.

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AbstractDuring the afternoon of 23 October 2022, a mesoscale convective system (MCS) developed and intensified over the English Channel and tracked north‐northeastward into southern England, producing widespread damaging winds and at least three moderate to strong tornadoes in Hampshire. In general, atmospheric temperature and moisture profiles from radiosonde observations and NOAA satellites indicated a high potential for severe thunderstorms, marginally severe straight‐line wind, and tornado occurrence over southern England. Radar and satellite observations showed coincidental high rain rate

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Gillot, Camille, Guilhem Dif-Pradalier, Yanick Sarazin, et al. "The problem of capturing marginality in model reductions of turbulence." Plasma Physics and Controlled Fusion, March 8, 2023. http://dx.doi.org/10.1088/1361-6587/acc276.

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Abstract Reduced quasilinear (QL) and nonlinear (gradient-driven) models with scale separations, commonly used to interpret experiments and to forecast turbulent transport levels in magnetised plasmas are tested against nonlinear models without scale separations (flux-driven). Two distinct regimes of turbulence --either far above threshold or near marginal stability-- are investigated with Boltzmann electrons. The success of reduced models especially hinges on the reproduction of nonlinear fluxes. Good agreement between models is found above threshold whilst reduced models would significantly

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Hof, Lotta, Till Moreth, Michael Koch, et al. "Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis." BMC Biology 19, no. 1 (2021). http://dx.doi.org/10.1186/s12915-021-00958-w.

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Abstract Background Organoids are morphologically heterogeneous three-dimensional cell culture systems and serve as an ideal model for understanding the principles of collective cell behaviour in mammalian organs during development, homeostasis, regeneration, and pathogenesis. To investigate the underlying cell organisation principles of organoids, we imaged hundreds of pancreas and cholangiocarcinoma organoids in parallel using light sheet and bright-field microscopy for up to 7 days. Results We quantified organoid behaviour at single-cell (microscale), individual-organoid (mesoscale), and en

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Brouwer, Emma J. P., Nikos Priovoulos, Julie Hashimoto, and Wietske van der Zwaag. "Proprioceptive engagement of the human cerebellum studied with 7T-fMRI." Imaging Neuroscience, 2024. http://dx.doi.org/10.1162/imag_a_00268.

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Abstract Proprioception, the process of perceiving our bodies in space, is a key aspect of self-perception. The cerebellar cortex is believed to play a critical role in proprioception. However, our understanding of the functional involvement of the cerebellum in proprioception remains limited due to the intricate, thin, and highly folded structure of the human cerebellar cortex, which is more challenging to resolve using in-vivo MRI compared to the cerebral cortex. In this study, we employed high-resolution, B1-shimmed, functional magnetic resonance imaging (fMRI) at 7T to investigate proprioc

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27

Richardson, Robin A., Benjamin S. Hanson, Daniel J. Read, Oliver G. Harlen, and Sarah A. Harris. "Exploring the dynamics of flagellar dynein within the axoneme with Fluctuating Finite Element Analysis." Quarterly Reviews of Biophysics 53 (2020). http://dx.doi.org/10.1017/s0033583520000062.

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Abstract Flagellar dyneins are the molecular motors responsible for producing the propagating bending motions of cilia and flagella. They are located within a densely packed and highly organised super-macromolecular cytoskeletal structure known as the axoneme. Using the mesoscale simulation technique Fluctuating Finite Element Analysis (FFEA), which represents proteins as viscoelastic continuum objects subject to explicit thermal noise, we have quantified the constraints on the range of molecular conformations that can be explored by dynein-c within the crowded architecture of the axoneme. We

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Gomarasca, Silvia, S. M. A. Hossein, Ran Tao, et al. "Assessment of the variability of unidirectional prepregs at multiple scales." e-Journal of Nondestructive Testing 30, no. 2 (2025). https://doi.org/10.58286/30713.

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Understanding the microstructural variability in unidirectional composite prepreg tapes is relevant to investigating mechanisms of tape microstructure formation, their impact on its processability and the mechanical performance of the final composite part. It has been shown that three-dimensional microstructural variability at the single-fibre level can be resolved by X-ray micro-computed tomography (XCT). However, to define a representative microstructural fingerprint of a given tape, investigations at the required small voxel size lead to limited volumes of observation, which might not be re

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Tumpa, Stasa, Rachel Thornton, Martin M. Tisdall, Torsten Baldeweg, Karl J. Friston, and Richard E. Rosch. "Interictal discharges spread along local recurrent networks between tubers and surrounding cortex." Journal of Physiology, March 17, 2025. https://doi.org/10.1113/jp288141.

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AbstractThe presence of interictal epileptiform discharges on EEG may indicate increased epileptic seizure risk. In highly epileptogenic lesions, such as cortical tubers in tuberous sclerosis, these discharges can be recorded with intracranial stereotactic EEG as part of the evaluation for epilepsy surgery. Yet the network mechanisms that underwrite the generation and spread of these discharges remain poorly understood. Here, we investigate the dynamics of interictal epileptiform discharges using a combination of quantitative analysis of invasive EEG recordings and mesoscale neural mass modell

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30

"Preface." Journal of Physics: Conference Series 2718, no. 1 (2024): 011001. http://dx.doi.org/10.1088/1742-6596/2718/1/011001.

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2023 International Conference on Frontiers of Ocean Science and Technology (ICFOST), sponsored by the College of Meteorology and Oceanology, National University of Defense Technology, was held successfully in Jiusuo Hotel Changsha from October 13 to 15, 2023. The Organizing Committees have invited experts in Marine science, Marine technology, Marine engineering, Marine resource exploration and application, Marine equipment R&D and manufacturing, etc. for academic exchanges. The Conference includes discussions on topics such as ocean circulation, air-sea interaction and ocean climate, ocean

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Short, Ewan, Todd P. Lane, and Claire L. Vincent. "Objectively Diagnosing Characteristics of Mesoscale Organization from Radar Reflectivity and Ambient Winds." Monthly Weather Review, November 30, 2022. http://dx.doi.org/10.1175/mwr-d-22-0146.1.

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Abstract In the classical model of mesoscale convective systems (MCSs), a system generates new convective cells on the down-shear side of its cold pool, with the cells fed at low levels from the front, and the stratiform cloud trailing behind the system in the up-shear direction, where “front” and “behind” typically refer to the system’s ground-relative velocity. In this study we present an algorithm for identifying and tracking MCSs in radar reflectivity data, and objectively diagnosing organisational characteristics related to the classical model, namely the offset of stratiform cloud from c

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Abubakar, Eleojo Oluwaseun, and Niall Cunningham. "Small-area estimation and analysis of HIV/AIDS indicators for precise geographical targeting of health interventions in Nigeria. a spatial microsimulation approach." International Journal of Health Geographics 22, no. 1 (2023). http://dx.doi.org/10.1186/s12942-023-00341-8.

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Abstract Background Precise geographical targeting is well recognised as an indispensable intervention strategy for achieving many Sustainable Development Goals (SDGs). This is more cogent for health-related goals such as the reduction of the HIV/AIDS pandemic, which exhibits substantial spatial heterogeneity at various spatial scales (including at microscale levels). Despite the dire data limitations in Low and Middle Income Countries (LMICs), it is essential to produce fine-scale estimates of health-related indicators such as HIV/AIDS. Existing small-area estimates (SAEs) incorporate limited

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