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Academic literature on the topic 'Meniscu'

Author: Grafiati
Published: 9 March 2023
Last updated: 10 March 2023

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Journal articles on the topic "Meniscu"

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Sandhya H, Sangeeta M, Khizer Hussain Afroze M, and Varalakshmi KL. "Retrospective Cross Sectional MRI Study of Morphometry of Menisci of Knee Joint." International Journal of Anatomy and Research 10, no. 2 (June 5, 2022): 8318–24. http://dx.doi.org/10.16965/ijar.2022.101.

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Introduction: Meniscal tears are commonly encountered in clinical practice and cause significant musculoskeletal morbidity. Most of the data available on Morphometry of menisci in Indian population are through cadaveric studies and very few MRI studies are available to substantiate the available data. Aim of the study: To gather data on the Morphometry of menisci in South Indian population and compare it with the existing literature. Material and Method: 100 MRI images collected retrospectively were used to study menisci. Height and width of MM and LM were measured both in sagittal and coronal planes. Results: It was observed that in both sexes the height of the Anterior horn of Medial meniscus was significantly higher than that of Lateral meniscus. Width of the Anterior horn and body showed significantly higher values in Lateral meniscus whereas width of Posterior horn of Medial meniscus showed significantly higher values in both sexes. Height of Medial meniscus in all the segments was higher in males though the difference was significant only in anterior horn and Posterior horn segments. Height of Lateral meniscus was significantly higher in males in all the segments. Conclusion: Results of this study will add to the existing literature on the Morphometry of menisci and will serve as a database for patients undergoing meniscal allografts. KEY WORDS: Medial meniscus, Lateral meniscus, Meniscal tears, musculoskeletal morbidity.
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Shea, Kevin G., Aleksei B. Dingel, Alexandra Styhl, Connor G. Richmond, Peter C. Cannamela, Allen F. Anderson, Theodore J. Ganley, Andrew Hill, and Yi-Meng Yen. "The Position of the Popliteal Artery and Peroneal Nerve Relative to the Menisci in Children: A Cadaveric Study." Orthopaedic Journal of Sports Medicine 7, no. 6 (June 1, 2019): 232596711984284. http://dx.doi.org/10.1177/2325967119842843.

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Background: Meniscal injury in skeletally immature patients is increasingly reported. During meniscal repair, all-inside devices may protrude beyond the posterior limits of the meniscus, putting the neurovascular structures at risk. Purpose: The purposes of this study were (1) to examine the relationship between the popliteal artery and the posterolateral and posteromedial aspects of the menisci, (2) to examine the relationship of the peroneal nerve to the posterolateral meniscus, and (3) to develop recommendations for avoiding neurovascular injury during posterior meniscal repair in pediatric patients. Study Design: Descriptive laboratory study. Methods: A total of 26 skeletally immature knee cadaveric specimens (7 females and 19 males) were included. Specimens were divided into age groups: 2-4, 5-8, and 9-11 years. The most posterior extent of the lateral and medial menisci was identified via sagittal and axial views on computed tomography (CT) scans. The shortest distance from the most posterior aspect of the lateral and medial menisci to the popliteal artery and the shortest distance from the posterior aspect of the lateral menisci to the anterior rim of the peroneal nerve were measured, and 3-dimensional models of representative specimens were re-created through use of CT scans. Results: For the age groups 2-4, 5-8, and 9-11 years, the mean minimum distance from the posterolateral meniscus to the popliteal artery was 5.2, 6.7, and 8.2 mm, respectively, and the mean minimum distance from the posteromedial meniscus to the popliteal artery was 12.7, 15.4, and 20.3 mm, respectively. In all groups, the distance between the posteromedial meniscus and the popliteal artery was greater than that between the posterolateral meniscus and the popliteal artery. The mean distance from the peroneal nerve to the lateral meniscus was 13.3, 15.0, and 17.9 mm for the respective groups. Conclusion: Many all-inside meniscal repair devices have sharp tips that penetrate posterior to the meniscus and capsule. This study demonstrated that the distance between the posterior meniscus and popliteal artery is relatively small in pediatric patients, especially for the lateral meniscus region. Clinical Relevance: Because of the higher potential for meniscal healing, meniscal repair is more likely to be performed in pediatric patients. The data in this study regarding the proximity of the lateral meniscus and neurovascular structures may be used to guide safe surgical repair of posterior meniscal tears during the use of all-inside meniscal repair devices in these patients.
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Van Dyck, Pieter, Filip M. Vanhoenacker, Jan L. Gielen, Lieven Dossche, Joost Weyler, and Paul M. Parizel. "Three-tesla magnetic resonance imaging of the meniscus of the knee: What about equivocal errors?" Acta Radiologica 51, no. 3 (April 2010): 296–301. http://dx.doi.org/10.3109/02841850903515403.

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Background: The significance of borderline magnetic resonance (MR) findings that are equivocal for a tear of the knee meniscus remains uncertain. Given their higher signal-to-noise ratio (SNR) and greater spatial resolution, these equivocal meniscal tears could be expected to be less frequent using a 3.0T MR system. Purpose: To investigate the prevalence of equivocal meniscal tears using 3.0T MR, and to study their impact on MR accuracy compared with arthroscopy in the detection of meniscal tears. Material and Methods: The medical records of 100 patients who underwent 3.0T MR imaging and subsequent arthroscopy of the knee were retrospectively reviewed. Two observers interpreted MR images in consensus, and menisci were diagnosed as torn (abnormality on two or more images), equivocal for a tear (abnormality on one image), or intact, using arthroscopy as the standard of reference. The prevalence of equivocal meniscal tears was assessed, and MR accuracy was calculated as follows: first, considering both torn menisci and equivocal diagnoses as positive for a tear; and second, considering only torn menisci as positive for a tear. Results: Evidence of meniscal tears on MR images was equivocal in 12 medial (12%) and three lateral (3%) menisci. Of these equivocal MR diagnoses, tears were found at arthroscopy in eight medial and one lateral meniscus. In our study, the specificity and positive predictive value increased for both the medial and lateral meniscus when only menisci with two or more abnormal images were considered to be torn: from 80% and 89% to 91% and 94% for the medial meniscus, and from 91% and 73% to 93% and 78% for the lateral meniscus, respectively. Conclusion: Subtle findings that are equivocal for a tear of the knee meniscus still make MR diagnosis difficult, even at 3.0T. We recommend that radiologists should rather be descriptive in reporting subtle or equivocal MR findings, alerting the clinician of possible meniscal tear.
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Yoon, Kyoung Ho, Sang Jun Song, Hee Sung Lee, and Cheol Hee Park. "Meniscal Injury Does Not Significantly Affect the Dimensions of the Intact Meniscus in the Opposite Compartment of the Knee." Orthopaedic Journal of Sports Medicine 8, no. 2 (February 1, 2020): 232596712090432. http://dx.doi.org/10.1177/2325967120904328.

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Background: Meniscal allograft transplant requires precise matching of the size of the allograft with the dimensions of the recipient knee. Estimation of contralateral meniscal size on magnetic resonance imaging (MRI) has been considered the ideal method to measure menisci before transplant. We questioned whether a contralateral intact meniscus with meniscal injury in the opposite compartment could be used as a reference to determine allograft size. Our question was derived from knowledge of meniscal injury influencing structures of the opposite compartment of the knee, including the meniscus. Purpose: To compare meniscal dimensions between intact meniscus with meniscal injury in the opposite compartment and normal meniscus with a normal opposite compartment. Study Design: Cross-sectional study; Level of evidence, 3. Methods: This observational, cross-sectional study was performed between 2016 and 2017. The control group consisted of 200 knees with normal medial and lateral menisci. The medial intact group consisted of 150 cases of medial intact meniscus with injured lateral meniscus, and the lateral intact group consisted of 150 cases of lateral intact meniscus with injured medial meniscus. All patients were male. Mean age, height, and weight did not differ among groups. We investigated meniscal dimensions on MRI, including anteroposterior and mediolateral lengths, distance between the anterior and posterior horns (AHPH distance), and widths and heights of the anterior and posterior horns and midbody. Results: Most medial meniscal dimensions were similar between the control and medial intact groups, but the AHPH distance was smaller in the medial intact group ( P < .001). Likewise, most lateral meniscal dimensions were similar between the control and lateral intact groups, but the AHPH distance was smaller in the lateral intact group ( P < .001). Conclusion: Most dimensions of the intact meniscus with meniscal injury in the opposite compartment were similar to those of the normal meniscus with normal opposite compartment. Measuring the dimensions of the contralateral intact meniscus with meniscal injury in the opposite compartment on MRI can be an appropriate method to determine meniscal allograft size.
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Lin, Kenneth M., Naomi E. Gadinsky, Craig E. Klinger, Jonathan P. Dyke, Scott A. Rodeo, Daniel W. Green, Peter D. Fabricant, David L. Helfet, Kevin G. Shea, and Lionel E. Lazaro. "MAGNETIC RESONANCE QUANTIFICATION OF MENISCUS VASCULARITY IN PEDIATRIC VERSUS ADULT KNEES." Orthopaedic Journal of Sports Medicine 8, no. 4_suppl3 (April 1, 2020): 2325967120S0023. http://dx.doi.org/10.1177/2325967120s00232.

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Background: Despite advances in surgical techniques, implant technology, and biological augmentation, one innate limitation to meniscus healing is lack of vascularity. Ability to quantify meniscal vascularity has been limited with previous techniques, and minimal data exists describing differential vascular zones in the skeletally immature meniscus. Purpose/Hypothesis: The objective of this study is to use quantitative contrast-enhanced magnetic resonance imaging (MRI) to compare meniscal vascularity in pediatric cadaveric specimens to adults. We hypothesize that the developing meniscus has greater and more uniform vascularity throughout all zones. Methods: We utilized 10 fresh-frozen human cadaveric knees (5 immature knees, age 0-6 months; 5 mature knees, age 34-67 years). Gadolinium-enhanced MRI was performed using a previously established vascularity quantification protocol. Regions of interest corresponding to peripheral and central zones of the meniscus were identified on pre-contrast coronal images, and signal enhancement (normalized against background tissue) was compared between pre-and post-contrast images (Figure 1). Results: Quantitative MRI demonstrated increased perfusion in the peripheral zones compared to the central zones (2.3:1 in immature knees and 3:1 in mature knees) in the medial and lateral menisci separately, and both menisci aggregated. Overall, the medial and lateral menisci had similar levels of perfusion in all specimens (45.9% ± 8.3% medial vs. 54.1% ± 8.3% lateral in immature knees; 50.5% ± 11.3% medial vs. 49.5% ± 11.3% lateral in mature knees). Immature specimens demonstrated greater overall normalized meniscal signal uptake, with the 0-month specimen demonstrating the greatest proportional signal enhancement. Conclusion: While blood flow to peripheral zones is greater than to central zones in both immature and adult menisci, younger menisci receive proportionally greater overall blood flow compared to adults, including greater blood flow to the inner zone, challenging the conventional wisdom of the central zone being avascular. As younger patients become increasingly active in sports, thorough understanding of the immature meniscus is required. Greater overall vascularity, including centrally, to the developing meniscus suggests improved healing potential following injury, and further encourages meniscal preservation when possible. [Figure: see text][Figure: see text]
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Hifny, Abdalla, Kamal Eldin Hashem Abdalla, Yousria A. Abdel Rahman, Khaled Aly, and Ruwaida Abdelmoaty Elhanbaly. "Morphometric studies on the passive role of menisci in upward fixation of the patella in buffalo and cattle." Veterinary Science Development 2, no. 1 (November 14, 2012): 14. http://dx.doi.org/10.4081/vsd.2012.4412.

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The present study showed that the medial and lateral compartments of the femorotibial joint have an intervening meniscus located between the femur and tibia. The lateral meniscus is semicircular and covers a larger portion of the tibial condyle than the medial meniscus. The lateral meniscus has cranial and caudal meniscal ligaments anchoring it to the tibia. The present investigation shows that the dimensions of the meniscal ligaments of buffalo and cattle are almost the same except for the caudal ligament of lateral meniscus and the meniscofemoral ligament. The caudal ligament of lateral meniscus is longer in buffalo than in cattle. Therefore, the femur moves more cranially than normal to straighten the joint. The meniscofemoral ligament is thicker in cattle (6.55±0.04 mm) than in buffalo (3.85±0.05 mm). Therefore, it helps to stabilize the movement of the menisci. Furthermore, the presence of the transverse genual ligament which fixes the two menisci cranially increases stability and prevents a more forward movement of the femur.
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Murphy, Caroline A., Atul K. Garg, Joana Silva-Correia, Rui L. Reis, Joaquim M. Oliveira, and Maurice N. Collins. "The Meniscus in Normal and Osteoarthritic Tissues: Facing the Structure Property Challenges and Current Treatment Trends." Annual Review of Biomedical Engineering 21, no. 1 (June 4, 2019): 495–521. http://dx.doi.org/10.1146/annurev-bioeng-060418-052547.

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The treatment of meniscus injuries has recently been facing a paradigm shift toward the field of tissue engineering, with the aim of regenerating damaged and diseased menisci as opposed to current treatment techniques. This review focuses on the structure and mechanics associated with the meniscus. The meniscus is defined in terms of its biological structure and composition. Biomechanics of the meniscus are discussed in detail, as an understanding of the mechanics is fundamental for the development of new meniscal treatment strategies. Key meniscal characteristics such as biological function, damage (tears), and disease are critically analyzed. The latest technologies behind meniscal repair and regeneration are assessed.
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Grimm, Nathan L., James Lee Pace, Benjamin J. Levy, D’Ann Arthur, Mark Portman, Matthew J. Solomito, and Jennifer M. Weiss. "Demographics and Epidemiology of Discoid Menisci of the Knee: Analysis of a Large Regional Insurance Database." Orthopaedic Journal of Sports Medicine 8, no. 9 (September 1, 2020): 232596712095066. http://dx.doi.org/10.1177/2325967120950669.

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Background: A discoid meniscus is a morphological variant of normal knee joint meniscus shape and ultrastructure that can lead to traumatic tearing of this tissue and early joint osteoarthritis. Purpose/Hypothesis: The purpose of this study was to determine the prevalence of discoid menisci in a large, ethnically diverse regional cohort and to evaluate possible risk factors. The hypothesis was that there would be no difference in the epidemiological distribution of discoid menisci based on ethnicity or sex. Study Design: Descriptive epidemiology study. Methods: The study population was from a regional, integrated health care system cohort from Kaiser Permanente of Southern California that, as of 2016, included more than 4.5 million patients. Patient demographics included age, sex, and ethnicity within this cohort. Potential risk factors analyzed included age, sex, ethnicity, and body mass index (BMI). Unique characteristics of a discoid meniscus were analyzed, including a symptomatic versus asymptomatic meniscus, location of meniscal tear and type of meniscus, and frequency of meniscal surgical treatment. Results: A total of 223 patients with a confirmed discoid meniscus were identified, yielding an overall prevalence rate of 4.88 per 100,000 patients. Those identifying as Black had the lowest prevalence (2.68/100,000), while Hispanic ethnicity had the highest (6.01/100,000). However, there was no significant difference with regard to ethnicity ( P = .283), nor any significant difference between sexes. BMI did not significantly influence the rate of discoid menisci ( P = .504). A majority (77.5%) of patients were symptomatic, while 22.5% of patients with discoid menisci were asymptomatic and discovered incidentally. Symptomatic discoid menisci were more likely to be operated on compared with asymptomatic discoid menisci (71% vs 14%, respectively; P = .001; odds ratio, 14.8 [95% CI, 5.8-37.2]). Horizontal and bucket-handle tears were the more common tear types. Of the discoid menisci in this cohort, 55.6% underwent surgery, with 95.2% undergoing reported saucerization. Conclusion: In this very diverse population-based cohort of patients, there did not seem to be a significant predilection of discoid menisci with regard to ethnicity. Neither sex nor BMI significantly influenced the rate of discoid menisci. More than three-quarters of those with a diagnosed discoid meniscus were symptomatic. Of the tears that occurred with discoid menisci, horizontal and bucket-handle tears made up the largest proportion.
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Kim, Sung-Soo, and Myung-Sang Moon. "CPM on Meniscal Regeneration and Maturation after Meniscectomy in Rabbits." Journal of Musculoskeletal Research 02, no. 03 (September 1998): 209–16. http://dx.doi.org/10.1142/s0218957798000202.

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This study in rabbit knees was carried out to clarify the effect of the application of CPM, after meniscectomy, on the regeneration rate of the meniscus and histology of the regenerated menisci. Twenty-seven mature rabbits were used: three rabbits as control (non-CPM) and 24 rabbits as experimental ones. Among them, four rabbits were used as the immediate CPM group and 20 rabbits as the delayed CPM group. In each animal, the medial meniscus was totally excised from the right knee, and the lateral meniscus was totally excised from the left knee. In three control animals, 16 weeks after meniscectomy, there was (hold) Grade II to III meniscal regeneration in two, and small meniscal mold was formed in one. In the immediate CPM group, meniscal regeneration failed and there was would disruption in all four knees. In the delayed CPM group, grades II to III regeneration was observed in 15 of the 20 medial meniscectomized knees, while in the lateral meniscectomized knees, the same size of meniscal regeneration was observed only in 3 of the 20 knees. The regenerated menisci in the delayed CPM group overall looked normal in appearance. Application of the delayed CPM induced the early fibrocartilaginous metaplasia of the regenerated fibrous menisci even at 6 to 12 weeks after meniscectomy. It is speculated that the application of delayed CPM promotes early focal fibrocartilagenous metaplasia of the fibrous meniscus following meniscectomy.
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Zantop, Thore, Yusuke Hashimoto, and Hiroaki Nakamura. "Prevalence, Development, and Factors Associated with Cyst Formation after Meniscal Repair with the All-Inside Suture Device." Orthopaedic Journal of Sports Medicine 8, no. 5_suppl4 (May 1, 2020): 2325967120S0032. http://dx.doi.org/10.1177/2325967120s00321.

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Aims and Objectives: The aim of this study is to investigate the prevalence of cyst formation as a complication of all-inside meniscal suture device using magnetic resonance imaging (MRI) and analyze the risk factors. Materials and Methods: Of the patients who had undergone meniscal repair surgery 46 cases (46 knees) were selected to be in the case-control study. 51 menisci (34 medial menisci, 17 lateral menisci) of 46 cases were included to the study. Out of 51 menisci, 46 menisci combined anterior cruciate ligament (ACL) ruptures and had performed ACL reconstruction (ACLR). 5 cases (5 menisci) had been performed meniscal repair (MR). MRIs of the knee were performed 6, 12 and 24 months post-meniscal surgery. The MRIs were examined to detect the new development of cysts encasing the suture anchors and evaluate meniscal healing. Univariate and multivariate risk factor analyses was used to account for the suture technique (suture device alone versus suture device and inside-out suture repair), concurrent operation (MR alone versus MR with ACL reconstruction), patient gender, medial versus lateral menisci, number of device use, side-to-side difference of knee arthrometer, type of anchor (acetal resin versus PEEK material) and clinical scores (Lysholm score, Tegner activity scale, IKDC score). Results: MRI examinations revealed cyst formation in 15 of 51 menisci. 3 menisci were detected cyst formation at 6 months of surgery, 9 at 12 months and 3 at 24 months. Only 3 patients (6.5%) were symptomatic. Tecxhniques using suture device alone was more likely to develop cysts: odds ratio (OR) was 10.67 (95% confidence interval (CI) 1.25 to 91.41). Medial meniscus statistically tended to develop cyst compared with lateral meniscus and OR was 7.92 (95% confidence interval (CI) 1.23 to 51.07). Patients who have instability (side-to-side difference of knee arthrometer > 3mm) are more likely to develop cysts than that ofless than or equal to 3mm (p = 0.06). Conclusion: This study revealed the risk factors and prevalence rate for cyst formation after using the all-inside meniscal suture device. The prevalence rate of cyst formation around suture implant was 29%, however most cases didn’t have any symptoms. Suture device only and medial meniscus were significant risk factors for cyst formation. Knee instability was greater in the cyst developed menisci though it was not significant, which suggested that knee instability could affect cyst formation around suture anchors.
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Dissertations / Theses on the topic "Meniscu"

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Ayres, Gustavo Garcia Francisco Algéos. "Meniscal injury associated with cranial cruciate ligament rupture in dogs : a retrospective case study." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2017. http://hdl.handle.net/10400.5/14654.

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Dissertação de Mestrado Integrado em Medicina Veterinária
Cranial cruciate ligament (CrCL) rupture is the most common orthopaedic disease in dogs and medial meniscal injury is very often associated with this condition. Concurrent meniscal damage can be diagnosed at the time of the stifle stabilization surgery, however, post-surgical meniscal tears can also develop and should be taken into account. This study incorporates a bibliographic review about medial meniscal tears associated with CrCL ruptures and a retrospective study of 22 stifles from 20 different dogs which were diagnosed with CrCL rupture and which meniscal integrity was evaluated. A craniomedial arthrotomy of the stifle was performed in all cases in order to diagnose meniscal damage. Meniscal tears were treated surgically in order to remove all of the damaged tissue and preserve as much healthy meniscal tissue as possible. 10 out of 22 stifles were diagnosed with concurrent meniscal injury during this study (45%). The rate of concurrent meniscal injury of this study is comparable to the previous published ones. In this retrospective study and bibliographic review it is concluded that meniscal pathology is a very common disease associated with CrCL rupture which should be treated since it causes chronic lameness, progression of osteoarthritis and pain to the patient.
RESUMO - LESÕES DE MENISCO ASSOCIADAS À ROTURA DO LIGAMENTO CRUZADO CRANIAL EM CÃES: ESTUDO DE CASOS RETROSPETIVO - A rotura do ligamento cruzado cranial (LCC) é a doença ortopédica mais comum em cães e a lesão do menisco medial é muito comumente associada a esta condição. Danos no menisco podem ser diagnosticadas aquando da cirurgia para estabilização do joelho, no entanto, lesões de menisco pós-cirúrgicas também se podem desenvolver e devem ser tidas em conta. Este estudo incorpora uma revisão bibliográfica sobre lesões de menisco associadas à rotura do LCC e um estudo retrospetivo de 22 joelhos de 20 cães diferentes aos quais foi diagnosticada a rotura do LCC e aos quais a integridade do menisco foi avaliada. Uma artrotomia craniomedial de joelho foi feita em todos os casos para diagnosticar lesões no menisco medial. As lesões identificadas foram tratadas cirurgicamente de modo a remover todo o tecido alterado e preservar tanto quanto possível o tecido saudável. Dos 22 joelhos, 10 foram diagnosticados com lesões de menisco (45%). Este valor pode ser comparável ao reportado por estudos publicados previamente. Neste estudo retrospetivo e revisão bibliográfica pode ser concluído que as lesões de menisco são uma condição associada à rotura do LCC e que deve ser tratada visto provocar claudicação crónica, dor e progressão da osteoartrite.
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Masferrer, Pino Ángel. "¿Es la capsulodesis la clave para evitar la extrusión meniscal después de un trasplante? Estudio clínico, radiológico y anatómico." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/671263.

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Aquesta tesi doctoral busca investigar si l'aplicació de la tècnica quirúrgica anomenada com "Capsulodesis" pot ser clau per evitar l'extrusió meniscal després d'un trasplantament meniscal lateral de genoll. A través d'un examen clínic, radiològic i anatòmic, cada un dels articles que composen aquesta tesi es va centrar en l'estudi d'un dels següents tres punts clau en el trasplantament meniscal al·logènic (TMA): 1. Comparar els resultats radiològics (en termes d'extrusió meniscal) i els resultats funcionals dels trasplantaments de loempelt de menisc lateral (TMA) realitzats mitjançant una tècnica de fixació òssia (barra òssia) o mitjançant una tècnica de fixació de teixits tous (túnels transóseos) després de realitzar prèviament una capsulodesis. 2. Comparar la quantitat d'extrusió meniscal després d'un TMA lateral realitzat amb una tècnica només de sutura, amb o sense capsulodesis associada, a més de comparar els resultats funcionals entre les dues tècniques. 3. Analitzar, quantificar i redefinir l'anatomia de les fixacions perifèriques de el cos de l'menisc lateral per comprendre millor com aquestes estructures podrien tenir un paper en la prevenció de l'extrusió meniscal i com podria aplicar-se a les tècniques quirúrgiques.
Esta tesis doctoral busca investigar si la aplicación de la técnica quirúrgica denominada como "Capsulodesis" puede ser clave para evitar la extrusión meniscal después de un trasplante meniscal lateral de rodilla. A través de un examen clínico, radiológico y anatómico, cada uno de los artículos que componen esta tesis se centró en el estudio de uno de los siguientes tres puntos clave en el trasplante meniscal alogénico (TMA): 1. Comparar los resultados radiológicos (en términos de extrusión meniscal) y los resultados funcionales de los trasplantes de aloinjerto de menisco lateral (TMA) realizados mediante una técnica de fijación ósea (barra ósea) o mediante una técnica de fijación de tejidos blandos (túneles transóseos) después de realizar previamente una capsulodesis. 2. Comparar la cantidad de extrusión meniscal después de un TMA lateral realizado con una técnica solamente de sutura, con o sin capsulodesis asociada, además de comparar los resultados funcionales entre ambas técnicas. 3. Analizar, cuantificar y redefinir la anatomía de las fijaciones periféricas del cuerpo del menisco lateral para comprender mejor cómo estas estructuras podrían desempeñar un papel en la prevención de la extrusión meniscal y cómo podría aplicarse a las técnicas quirúrgicas.
This doctoral thesis seeks to investigate whether the application of the surgical technique known as "Capsulodesis" can be key to avoiding meniscal extrusion after a lateral meniscal knee transplant. Through a clinical, radiological and anatomical examination, each of the articles that make up this thesis focused on the study of one of the following three key points in allogeneic meniscal transplantation (MAT): 1. Compare the radiological results (in terms of meniscal extrusion) and the functional results of lateral meniscus allograft transplantation (MAT) performed using a bone fixation technique (bone bar) or a soft tissue fixation technique (tunnels transosseous) after previously performing a capsulodesis. 2. Compare the amount of meniscal extrusion after a lateral MAT performed with a suture-only technique, with or without associated capsulodesis, in addition to comparing the functional results between both techniques. 3. Analyze, quantify, and redefine the anatomy of the peripheral attachments of the body of the lateral meniscus to better understand how these structures might play a role in preventing meniscal extrusion and how it could be applied to surgical techniques.
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Ferrari, Márcio Balbinotti. "Reparo meniscal em crianças e adolescentes : uma revisão sistemática de resultados." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/174843.

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OBJETIVO: Realizar uma revisão sistemática da literatura existente, a fim de analisar os resultados após o reparo meniscal na população pediátrica. MÉTODOS: Uma revisão sistemática foi realizada de acordo com as diretrizes PRISMA usando os Bancos de Dados de Análise Sistemática Cochrane, Registro Central Cochrane de ensaios controlados, MEDLINE Ovid e MEDLINE PubMed. Os critérios de inclusão foram os seguintes: estudos que relatam os resultados do reparo meniscal em pacientes com 18 anos ou menos, com um seguimento médio mínimo de 12 meses, idiomas português, espanhol ou inglês e estudos humanos incluindo 10 ou mais pacientes. RESULTADOS: Nossa pesquisa identificou 2534 títulos individuais. Após a aplicação dos critérios de inclusão e exclusão, foram incluídos oito estudos, avaliando 287 pacientes com lesões meniscais reparadas. Sete estudos foram classificados como nível de evidência IV e um nível III. O escore médio MINORS foi de 8,6 ± 1,4. O reparo meniscal incluiu todas as zonas meniscais e padrões de lesões. A lesão do ligamento cruzado anterior foi a lesão associada mais comum. As técnicas “inside-out” e “all-inside” foram predominantemente relatadas. A maioria dos pacientes relatou resultados bons a excelentes e teve sinais clínicos de cicatrização meniscal; as meniscectomias após reparação meniscal foram realizadas em apenas 44 casos. CONCLUSÃO: Lesões meniscais em pediatria não são incomuns. O reparo desta lesão foi associado com resultados bons a excelentes na maioria dos pacientes, independentemente do padrão de lesão, zona ou técnica. As complicações relatadas foram mínimas, no entanto, são necessários estudos de maior qualidade para confirmar os achados desta revisão sistemática. NÍVEL DE EVIDÊNCIA: Nivel IV, revisão sistemática de estudos nível III e nível IV.
PURPOSE: To perform a systematic review of existing literature in order to analyze outcomes after meniscal repair in the pediatric population. METHODS: A systematic review was performed according to PRISMA guidelines using the Cochrane Database of Systematic Review, Cochrane Central Register of Controlled Trials, MEDLINE Ovid, and MEDLINE PubMed databases. Inclusion criteria were as follows: studies reporting the outcomes of meniscal repair in patients 18 years old or younger, with a minimum mean follow-up of 12 months, Portuguese, Spanish or English languages, and human studies including 10 or more patients. RESULTS: Our search identified 2534 individual titles. After application of the inclusion and exclusion criteria, 8 studies were included, evaluating 287 patients with repaired meniscal tears. Seven studies were classified as level of evidence IV and one level III. The mean MINORS score was 8.6 ± 1.4. Meniscal repair included all meniscal zones and tear patterns. Anterior cruciate ligament tear was the most common associated injury. The all-inside and inside-out techniques were predominantly reported. The majority of the patients reported good to excellent outcomes and had clinical signals of meniscal healing; meniscectomies following meniscal repair were performed in just 44 cases. CONCLUSION: Meniscal tears in pediatrics are not uncommon. Repairs of this injury were associated with good to excellent outcomes in most patients, regardless of the injury pattern, zone or technique. Reported complications were minimal, however, higher quality studies are needed to confirm the findings of this systematic review. LEVEL OF EVIDENCE: Level IV, systematic review of Level III and Level IV studies.
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Alvarellos, Jose. "Fundamental Studies of Capillary Forces in Porous Media." Diss., Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/5314.

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The contact angle defined by Young's equation depends on the ratio between solid and liquid surface energies. Young's contact angle is constant for a given system, and cannot explain the stability of fluid droplets in capillary tubes. Within this framework, large variations in contact angle and explained aassuming surface roughness, heterogeneity or contamination. This research explores the static and dynamic behavior of fluid droplets within capillary tubes and the variations in contact angle among interacting menisci. Various cases are considered including wetting and non-wetting gluids, droplets in inclined capillary tubes or subjected to a pressure difference, within one-dimensional and three-dimensional capillary systems, and under static or dynamic conditions (either harmonic fluid pressure or tube oscillation). The research approach is based on complementary analytical modeling (total energy formulation) and experimental techniques (microscopic observations). The evolution of meniscus curvatures and droplet displacements are studied in all cases. Analytical and experimental results show that droplets can be stable within capillary tubes even under the influence of an external force, the resulting contact angles are not constant, and bariations from Young's contact angle aare extensively justified as menisci interaction. Menisci introduce stiffness, therefore two immiscible Newtonian fluids behave as a Maxwellian fluid, and droplets can exhibit resonance or relaxation spectral features.
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Tumia, Nezar S. "The knee meniscus : investigating the regenerative potential of meniscal cartilage exposed to recombinant growth factors in vitro." Thesis, University of Aberdeen, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430973.

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Meniscal tears are common debilitating injuries that can have dramatic consequences especially for young athletes.  Healing of meniscal tears following surgical repair is essentially only feasible for tears within the peripheral vascular zone.  By comparison, tears that occur within the inner avascular zone do not heal and most commonly are treated by excision.  This in turn greatly increases the potential for secondary osteoarthrosis.  Clearly, there is a clinical need to augment surgical techniques, extending meniscal repair to the avascular zone. In this study, monolayer cell cultures were prepared from the inner, middle, and outer zones of the lateral menisci of sheep and from humans obtained following total knee arthroplasty and partial meniscectomy.  Various concentrations of Platelet Derived Growth Factor (PDGF-AB), Insulin-like Growth Factor type I (IGF-I), and basic Fibroblast Growth Factor (bFGF) were used individually to assess their effects upon cell proliferation and extracellular matrix formation. This study found that the growth factors under investigation stimulated the fibrochondrocytes, both human and sheep, in a similar dose dependent fashion, although the specifics and extent of stimulation differed for each of the growth factors, and for each species.  Interestingly, fibrochondrocytes cultured from the avascular zone were stimulated in a similar fashion to those cultured from the vascular zone.  The action of the growth factors was not dependent upon serum being present. Therefore, the results of this study are an encouraging first step towards enhancing the regeneration and potentially the repair of injured meniscal tissue.
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POLITO, UMBERTO. "THE MENISCUS: BASIC SCIENCE TO IMPROVE KNOWLEDGE FOR TISSUE ENGINEERING." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/707236.

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This thesis was thought with the intent to try to fill some lacunae in the knowledge of the anatomic-dependent features of the meniscus. In particular, the study of the effects of endogenous and exogenous factors upon the development of this structure will be outlined. Endogenous factors have been considered those factors that cannot be attributed to external or experimental factors: the effect of age and growth has been investigated focusing on the variation of the, matrix components (collagen types, GAGs and decorin), cellular phenotypic modifications and meniscal morpho-functional structure, with additional focus on possible differences presented in different animal models. On the other hand, exogenous factors have been considered those factors that are in any way attributable to the external interventions operated by the experimenter or by the application of forces upon meniscus. As exogenous factors, the effects of physiologic (compression and traction to which meniscus is naturally subjected) and non-physiologic (continuous compression without flexion) forces applied to meniscus during growth were evaluated. Furthermore, the effect of hypoxia in meniscal tissue-culture was also evaluated in a neonatal committed cell population in order to assess a faster maturation of the tissue. The importance of these investigations is linked to the possible application of these notions in the field of tissue engineering of the meniscus and may improve the current knowledge on the morpho-functional effect that external factors exercise on its structure.
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Cornelius, Ryan Marks Corey. "Meniscus." [Denton, Tex.] : University of North Texas, 2007. http://digital.library.unt.edu/permalink/meta-dc-3685.

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Cornelius, Ryan. "Meniscus." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc3685/.

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Wataya, Celio Hitoshi. "Desenvolvimento de menisco de poli(álcool vinílico) (PVA) personalizado com auxílio da prototipagem rápida." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263546.

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Orientadores: Cecilia Amelia de Carvalho Zavaglia, Vanessa Petrilli Bavaresco
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecânica
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Resumo: O menisco como qualquer outro órgão, possui sua importância no funcionamento total do corpo humano. O tratamento para as lesões do menisco tem sido substituído pelo reparo, entretanto, conforme a gravidade da lesão torna-se inevitável a meniscectomia (cirurgia do menisco). Diante desta situação propôs-se desenvolver uma prótese que substitua o menisco lesionado, que possua suas características dimensionais, bem como suas propriedades mecânicas e tribológicas. A utilização da tecnologia da prototipagem rápida foi fundamental para se alcançar efetivamente o objetivo proposto. O material selecionado para a obtenção dessa prótese foi o poli(álcool vinílico) (PVA), por ser um polímero de baixo custo de produção, fácil obtenção e boas características para ser utilizado como um biomaterial. Os resultados dos ensaios mecânicos confirmaram a eficácia desse material. Valores como módulo de compressão 37,4 MPa (± 1,74), o módulo de fluência a indentação E = 3,6 MPa (±0,6); módulo de tensão e deformação, respectivamente iguais a 'SIGMA' = 3,2 MPa (±0,3) e ? = 148,4% (±39), evidenciam a possibilidade de utilização do PVA também como substituto do menisco humano. Outros ensaios também foram realizados como: ensaio in vitro e in vivo, tribológico e a Calorimetria Diferencial de Varredura (DSC), com resultados favoráveis a esse fim. Para a obtenção do menisco de PVA nas dimensões do menisco do paciente utilizou-se a tecnologia da prototipagem rápida (PR), primeiro para se obter o molde do menisco e depois então, o menisco por envasamento da solução de PVA no molde. Dois detalhes foram fundamentais para se chegar ao produto final, o primeiro foi o tratamento computacional dado à imagem de tomografia do joelho utilizando-se de programas livres como Invesalius e Rhinoceros e o segundo foi o uso do reticulante físico, o reagente orgânico dimetilsulfóxido (DMSO)
Abstract: The meniscus like any other organ, has its importance in the total functioning of the human body. The treatment for meniscal injuries has been replaced by the repair, however, according to the severity of the injury becomes inevitable meniscectomy (meniscus surgery). In this situation it was proposed to develop a prosthesis to replace the injured meniscus, which have their dimensional characteristics as well as their mechanical and tribological properties. The use of rapid prototyping technology was essential to effectively achieve the proposed objective. The material selected for obtaining a prosthesis is poly (vinyl alcohol) (PVA), being a polymer of low production cost, and easy to obtain good characteristics for use as a biomaterial. The results of mechanical tests have confirmed the effectiveness of this material. Values like compression module 37.4 MPa (± 1.74), the modulus of creep indentation E = 3,6 MPa (± 0.6), tensile modulus and strain, respectively equal to ' SIGMA' = 3.2 MPa (± 0.3) and ? = 148.4% (± 39) show the possibility of use of PVA as well as replacement of the meniscus human. Other tests were also conducted as in vitro and in vivo tribological and Differential Scanning Calorimetry (DSC), with results favorable to that end. To obtain the meniscus of PVA in the dimensions of the meniscus of the patient if the technology used rapid prototyping (RP), first to obtain the mold of the meniscus after then, the meniscus by filling the PVA solution in the mold. Two things were essential to reach the final product, the first treatment was given to computer tomography imaging of the knee using free programs like Rhinoceros and InVesalius and the second was the use of physical crosslinking, the organic reagent dimethyl sulfoxide (DMSO)
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Materiais e Processos de Fabricação
Doutor em Engenharia Mecânica
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Esposito, Andrea Rodrigues. "Crescimento de fibrocondrócitos sobre arcabouço de PLDLA/PCL-T para aplicação como prótese de menisco." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263902.

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Orientador: Eliana Aparecida de Rezende Duek
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecânica
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Resumo: A engenharia tecidual utilizando células fibrocartilaginosas e arcabouços poliméricos representa uma alternativa para o tratamento de lesões do menisco. Neste estudo, arcabouços de PLDLA/PCL-T (90/10) contendo sacarose (50% m/v) foram obtidos por evaporação de solvente. Fibrocondrócitos provenientes do menisco de coelhos foram isolados e semeados diretamente sobre os arcabouços. Estudos in vitro demonstraram que o arcabouço não apresentou citotoxicidade e permitiu a adesão e o crescimento de fibrocondrócitos, bem como manutenção da síntese de matriz extracelular colágena nos tempos de 7, 14, 21 e 28 dias de cultivo. Os implantes de PLDLA/PCL-T foram realizados no menisco medial do joelho de 20 coelhos, após a meniscectomia total, obtendo-se três tratamentos: arcabouço com pré-cultivo celular por 21 dias, arcabouço sem células e controle. Após 12 e 24 semanas, as análises histológicas dos "neomeniscos" apresentaram a formação de fibrocartilagem nos implantes com os arcabouços. A presença de tecido fibrocartilaginoso maduro com fibras colágenas organizada foi predominantemente observada nos implantes realizados com os arcabouços pré-cultivados em comparação com os implantes sem células após 24 semanas. Este estudo demonstrou que a regeneração de uma importante estrutura fibrocartilaginosa pode ser alcançada utilizando arcabouço polimérico biorreabsorvível e células alógenas dentro dos princípios da engenharia de tecidos
Abstract: Tissue engineering of meniscus using fibrochondrocyte-like cells and bioreabsorbable polymer scaffolds could be an alternative option to treat meniscus injury. In this study PLDLA/PCL-T (90/10) scaffolds containing sucrose (50% m/v) were obtained by casting. Allogeneic meniscal cells were isolated from rabbit meniscus and directly seeded onto the scaffolds. In vitro studies showed that scaffolds did not present cytotoxicity and allowed fibrochondrocytes adhesion and ingrowth, as well as collagen extracellular matrix synthesis at 7, 14, 21 and 28 days of culture. The PLDLA/PCL-T implants were performed in the medial meniscus of 20 rabbit knee after total meniscectomy, obtained three treatments: pre-seeded 21 days scaffold, unseeded scaffold and control. Histology analysis of "neomenisci" sections at 12 and 24 weeks revealed the presence of fibrocartilage in the polymer implants. The presence of mature fibrocartilaginous tissue with organized collagen fibers was predominantly observed in the pre-cultured implants compared to unseeded implants after 24 weeks. This study demonstrates that regeneration of an important fibrocartilaginous structure can be achieved using a bioreabsorbable polymer scaffold and allogeneic cells-based tissue engineering approaches
Mestrado
Materiais e Processos de Fabricação
Mestre em Engenharia Mecânica
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Books on the topic "Meniscu"

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LaPrade, Robert F., Elizabeth A. Arendt, Alan Getgood, and Scott C. Faucett, eds. The Menisci. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53792-3.

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Beaufils, Philippe, and René Verdonk, eds. The Meniscus. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-02450-4.

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Beaufils, Philippe, and René Verdonk. The meniscus. Heidelberg: Springer Verlag, 2010.

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Meniscus: Poems. Emeryville, Ont: Biblioasis, 2009.

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Neilson, Shane. Meniscus: Poems. Emeryville, Ont: Biblioasis, 2009.

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Athanasiou, Kyriacos A., and Johannah Sanchez-Adams. Engineering the Knee Meniscus. Cham: Springer International Publishing, 2009. http://dx.doi.org/10.1007/978-3-031-02576-1.

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Hulet, Christophe, Helder Pereira, Giuseppe Peretti, and Matteo Denti, eds. Surgery of the Meniscus. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-49188-1.

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Mhaskar, Vikram Arun. Inside Out Meniscus Repair. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0611-6.

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Kelly, IV, John D., ed. Meniscal Injuries. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-8486-8.

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Verdonk, René, João Espregueira Mendes, and Joan Carles Monllau, eds. Meniscal Transplantation. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38106-5.

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Book chapters on the topic "Meniscu"

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Verdonk, René, Peter Verdonk, and Eva Lisa Heinrichs. "Meniscal Substitutes: Polyurethane Meniscus Implant: Technique and Results." In Sports Injuries, 1191–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-36569-0_75.

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Verdonk, René. "Meniscal Substitutes: Polyurethane Meniscus Implant – Technique and Results." In Sports Injuries, 329–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-15630-4_44.

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Verdonk, René, Peter Verdonk, and Eva Lisa Heinrichs. "Meniscal Substitutes: Polyurethane Meniscus Implant - Technique and Results." In Sports Injuries, 1–8. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-36801-1_75-1.

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Zellner, Johannes, and Peter Angele. "Save the Meniscus: Advances in Meniscal Repair Techniques." In Advances in Knee Ligament and Knee Preservation Surgery, 303–12. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84748-7_25.

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Sarkissian, Eric J., and Theodore J. Ganley. "Meniscal Injuries and Discoid Lateral Meniscus in Adolescent Athletes." In Sports Injuries, 2577–87. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-36569-0_211.

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Melanotte, P. L., and M. Baldovin. "Surgical Repair of Chronic Meniscal Injury: Plastic Meniscus Surgery." In Surgery and Arthroscopy of the Knee, 336–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-72782-5_67.

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Sarkissian, Eric J., and Theodore J. Ganley. "Meniscal Injuries and Discoid Lateral Meniscus in Adolescent Athletes." In Sports Injuries, 1–13. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36801-1_211-2.

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Geffroy, Loïc, and Nicolas Bouguennec. "Meniscal Lesions in Children: Classification, Discoid Meniscus, Traumatic Lesions." In Surgery of the Meniscus, 107–17. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-49188-1_10.

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Bae, Ji Hoon. "Meniscal Injury and Surgical Treatment: Meniscectomy and Meniscus Repair." In Knee Arthroscopy, 179–200. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-8191-5_16.

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Niitsu, Mamoru. "Meniscus." In Magnetic Resonance Imaging of the Knee, 85–121. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-17893-1_7.

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Conference papers on the topic "Meniscu"

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Netravali, Nathan A., Nicholas J. Giori, and Thomas P. Andriacchi. "Meniscal Movement During the Gait Cycle Is Sensitive to the Attachment Properties of the Meniscal Horns." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-205269.

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The menisci are integral structures within the knee that help provide conforming surfaces between the femoral and tibial cartilage by moving as the knee flexes and thus reducing the contact stresses on the articular cartilage in the knee throughout the knee’s wide range of motion [1]. The menisci are firmly rooted in the tibial plateau at the anterior and posterior horns with more lax attachment in central regions. Thus, the stiffness of these meniscal attachments at the horns is an important consideration when evaluating meniscal function. Hence it is crucial to properly represent the attachment of the menisci at the anterior and posterior horns when evaluating normal motion of the menisci during knee movement. While finite element (FE) models of the tibio-menisco-femoral joint have been useful tool in evaluating meniscal function, previous FE models [2–5] of the knee joint that include the meniscus have not addressed the movement of the menisci during daily activities. Yet it is precisely this mobility of the menisci that permits them to adapt to the movement of the articular surfaces during typical activities and prevent injuries. Thus, the objective of this study was to simulate meniscal motion during a portion of the gait cycle and investigate the sensitivity of meniscal attachment stiffness using a finite element model. A previously established method [4] for attaching the meniscal horns to the tibia was used and its material properties were varied to determine the sensitivity of the movement of the menisci to the properties of the attachments at the horns.
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Linder-Ganz, Eran, Jonathan J. Elsner, Gal Zur, Jonathan Shani, Ori Brenner, Elliott Hershman, Avi Shterling, and Farshid Guilak. "Chondroprotective Effects of a Polycarbonate-Urethane Meniscal Implant: Semi-Quantitative Results in a Sheep Model." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19048.

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The menisci play a critical role in load-bearing and stability of the knee joint [1]. Damage or removal of the meniscus leads to alterations in the magnitude and distribution of stresses in the knee, which have been associated with degenerative osteoarthritis [2]. Clearly, there remains a need to develop means of protecting the articular cartilage following meniscal injury by either repairing or replacing the menisci. While allograft meniscal replacements can improve joint stability and function, they often provide little benefit in preventing osteoarthritic changes [3]. The development of an artificial meniscus that is available at the time of surgery in several sizes that can accommodate most patients would provide important therapeutic potential for treatment meniscal injury.
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Killian, Megan L., Dan Isaac, Roger C. Haut, Loic M. Dejardin, Darin Leetun, and T. L. Haut Donahue. "Traumatic Anterior Cruciate Ligament Tear and Its Implications on Meniscal Degradation: A Preliminary Novel Lapine Osteoarthritis Model." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-205106.

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The meniscus plays a crucial role in the dynamics of the knee. Damage to the meniscus can influence proprioception, stability, and mobility of the knee [1]. Risk factors of meniscal tears include prolonged or repeated deep knee bending, obesity, and sporting injuries [2]. Acute injury, as seen in alpine sports, involves complex dynamics which can damage singular or multiple tissue structures of the knee [2]. It is not uncommon for meniscal injuries to occur in conjunction with ACL lesions, and the loading imbalance that results in ACL lesions may also initiate meniscal tears [3, 4]. Investigations of meniscal tears following ACL rupture have indicated chronic damage to medial menisci more so than lateral menisci [5]. However, experimental studies of acute damage following ACL transection are not consistent, with some showing more lateral damage acutely and some showing equality between medial and lateral meniscal damage [5].
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Elsner, Jonathan J., Gal Zur, Farshid Guilak, Eran Linder-Ganz, and Avi Shterling. "Design Optimization of a Polycarbonate-Urethane Meniscal Implant in the Sheep Knee: In-Vitro Study." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19047.

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Meniscus replacement still represents an unsolved problem in orthopedics. Allograft meniscus implantation has been suggested as a means to restore contact pressures following meniscectomy. However, issues such as graft availability, disease transmission, and size matching still limit the use of allograft menisci. Furthermore, the complexities of meniscal repairs may contribute to uneven distribution of load, instability and initiation of degenerative damage. A synthetic meniscal substitute could have significant advantages for meniscal replacement, as it could be available at the time of surgery in a substantial number of sizes and shapes to accommodate most patients. There is, however, a need to establish an optimal configuration of such an implant that would result in pressure distribution ability closest to that of the natural meniscus.
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Linder-Ganz, Eran, Gal Zur, Jonathan Shani, Jonathan J. Elsner, Ori Brenner, Steven P. Arnoczky, Gabriel Agar, Elliott B. Hershman, and Avi Shterling. "Can a Polycarbonate-Urethane Meniscal Implant Protect Articular Cartilage? Histopathological Results in a Sheep Model." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204860.

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The menisci play an important role in the knee joint biomechanics [1]. Clinical studies have shown that the loss of the meniscus leads to degenerative arthritis attributed to the changes in load distribution and the loss of proprioception [2]. Clearly, there is a substantial need to protect the articular cartilage by either repairing or replacing the menisci. There are many difficulties dealing with both fresh frozen or cryopreserved allograft menisci, and the complexities of meniscal repairs may contribute to uneven distribution of load, instability and recurrence of degenerative damage. Hence there is a need for the development of an artificial meniscus that is available at the time of surgery in several sizes that can accommodate most patients.
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Yao, Jiang, Jason C. Snibbe, Michael D. Maloney, and Amy L. Lerner. "Effects of Partial and Total Meniscectomy on Kinematics of the Knee: A Magnetic Resonance Imaging Study." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43152.

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Meniscal injuries frequently occur in combination with anterior cruciate ligament (ACL) tears. Tears in the menisci that occur acutely with ACL injury are located either medially or laterally, but in ACL deficient knees chronic instability most commonly leads to meniscal tears in the posterior horn of medial meniscus (Smith & Barrett, 2001). Levy et al. (1982) suggested that medial meniscus might act as a mechanical wedge preventing tibial anterior translation due to its firm attachment to the tibia at the posterior horn. Previous biomechanical studies infer the role of the meniscus through measurements of alternations in forces or knee motions (Shoemaker & Markolf, 1986; Allen, 2000), however no study has provided clear images of the motion or deformation of the meniscus itself. The objective of this study was to investigate the effects of anterior cruciate ligament resection, as well as partial and complete meniscectomies on knee kinematics in response to anterior loading. Application of loads during magnetic resonance (MR) imaging allows us to visualize the motion and deformation of the menisci, and therefore obtain a more clear understanding of its role in knee stability.
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7

Abraham, Adam C., Megan L. Killian, and Tammy L. Haut Donahue. "Correlation of Nanomechanical and Mineral Properties of Human Osteoarthritic Meniscal Attachments." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19457.

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Meniscal horns attach the meniscus to the underlying subchondral bone. Successful meniscal replacements must maintain horn attachments of the menisci, hence recent studies have been aimed at characterizing the material properties of the ligamentous horn attachments. In order to mimic material properties in tissue engineered meniscal replacements, we must understand how these properties are influenced by mineral and matrix constituents. Additionally, understanding how osteoarthritis alters the meniscal horn attachments may elucidate appropriate design considerations of such tissue engineered replacements. Therefore, this study investigated the relationship between mechanical and mineral properties of osteoarthritic meniscal attachments.
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8

Killian, Megan L., Nicole M. Lepinsky, Dan I. Isaac, Roger C. Haut, and T. L. Haut Donahue. "Regional Glycosaminoglycan Coverage of Healthy Rabbit Menisci." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206224.

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The meniscus is an important load-bearing structure in the knee, as it provides load distribution and cushioning properties during weight-bearing activities. The compressive modulus and permeability of the meniscus is attributed to the tissue’s glycosaminoglycan (GAG) content, as charged proteoglycan side chains allow for tissue swelling and resistance to compression [1]. The distribution of sulphated GAGs throughout the meniscus has not been thoroughly documented. Although load differs across the knee joint, few researchers have investigated medial/lateral and coronal differences in meniscal architecture and GAG distribution [2, 3]. It is hypothesized that the distribution of positive histological staining for sulfated GAGs will differ across spatial regions of rabbit menisci. Primarily, it is hypothesized that regions of the menisci that likely see higher loading will demonstrate an increase in sulfated GAG-positive staining area.
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9

Ionescu, Lara C., Grant H. Garcia, Tiffany L. Zachry, Gregory C. Lee, Brian J. Sennett, and Robert L. Mauck. "In Vitro Meniscus Integration Potential is Inversely Correlated With Tissue Maturation State." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19369.

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Meniscal surgeries are amongst the most common procedures performed in orthopedics today. Clinical solutions are few and have limited success, and so partial meniscectomy is a common outcome. While tears are common in older patients, few young patients present with meniscus damage. It is unclear whether juvenile menisci are less susceptible to damage or more given to endogenous repair. Early in development, the menisci are well vascularized throughout their radial expanse, while in adults, vascularity is restricted to the peripheral rim of the tissue, near the synovial margin [1]. Tears in this vascular region often do heal in adults, while those in the avascular inner regions of the tissue do not [2]. This has led to the inference that vascularity is essential for meniscus healing and this manner of thinking has directed numerous repair strategies toward that end [3].
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Moyer, John T., Adam C. Abraham, Megan L. Killian, and Tammy L. Haut Donahue. "Transverse Mechanical Properties of Human Lateral Meniscal Attachments." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19458.

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The human knee joint bends during gait, running or similar dynamic activity. During such activity the ligaments and menisci provide joint stability. It is well know that the collagen fibers in knee ligaments are aligned parallel to the primary loading direction. In the knee meniscus, the fibers are aligned specifically to assist in the in vivo loading conditions. The human menisci are firmly attached to the tibia by means of ligamentous structures known as meniscal attachments [1]. Meniscal attachments are best modeled as fiber composite materials where the matrix is the ground substance and the collagen fibers are the reinforcement. The load is primarily transferred to the insertion sites which are designed to reduce the stress concentrations caused by the load transfer across the attachment-bone interface [1]. Determination of the transverse properties of human meniscal attachments will aid in the development of three dimensional knee joint models in which the attachments are treated as transversely isotropic, hyperelastic [2].
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Reports on the topic "Meniscu"

1

Rosen, Vicki. Identification, Characterization, and Utilization of Adult Meniscal Progenitor Cells. Fort Belvoir, VA: Defense Technical Information Center, September 2014. http://dx.doi.org/10.21236/ada613480.

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