Academic literature on the topic 'Membrane implicite'

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Journal articles on the topic "Membrane implicite"

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Amrouche, Fethia, Bouziane Mahmah, Maiouf Belhamel, and Hocine Benmoussa. "Modélisation d’une pile à combustible PEMFC alimentée directement en hydrogène-oxygène et validation expérimentale." Journal of Renewable Energies 8, no. 2 (2005): 109–21. http://dx.doi.org/10.54966/jreen.v8i2.856.

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La pile à combustible (PAC) est connue depuis longtemps comme un convertisseur d’hydrogène en énergie (électrique + thermique) possédant de très bons rendements, les recherches sur cette technologie se développent partout dans le monde de manière considérable. Les raisons sont bien connues: la réponse aux contraintes environnementales, aux problèmes posés par la production centralisée d’électricité, la nécessité d’avoir des alternatives énergétiques (vecteur hydrogène) et certaines exigences technologiques spécifiques telles que les applications spatiales, sous-marines, électroniques portables
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Tian, Ye, Charles Schwieters, Stanley Opella, and Francesca Marassi. "NMR-Restrained Structure Calculations of Membrane Proteins in Implicit Lipid Bilayer Membranes." Biophysical Journal 108, no. 2 (2015): 251a. http://dx.doi.org/10.1016/j.bpj.2014.11.1389.

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Sáenz, James P., Daniel Grosser, Alexander S. Bradley, et al. "Hopanoids as functional analogues of cholesterol in bacterial membranes." Proceedings of the National Academy of Sciences 112, no. 38 (2015): 11971–76. http://dx.doi.org/10.1073/pnas.1515607112.

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The functionality of cellular membranes relies on the molecular order imparted by lipids. In eukaryotes, sterols such as cholesterol modulate membrane order, yet they are not typically found in prokaryotes. The structurally similar bacterial hopanoids exhibit similar ordering properties as sterols in vitro, but their exact physiological role in living bacteria is relatively uncharted. We present evidence that hopanoids interact with glycolipids in bacterial outer membranes to form a highly ordered bilayer in a manner analogous to the interaction of sterols with sphingolipids in eukaryotic plas
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Zelhof, Andrew C., Hong Bao, Robert W. Hardy, Azam Razzaq, Bing Zhang, and Chris Q. Doe. "DrosophilaAmphiphysin is implicated in protein localization and membrane morphogenesis but not in synaptic vesicle endocytosis." Development 128, no. 24 (2001): 5005–15. http://dx.doi.org/10.1242/dev.128.24.5005.

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Amphiphysin family members are implicated in synaptic vesicle endocytosis, actin localization and one isoform is an autoantigen in neurological autoimmune disorder; however, there has been no genetic analysis of Amphiphysin function in higher eukaryotes. We show that Drosophila Amphiphysin is localized to actin-rich membrane domains in many cell types, including apical epithelial membranes, the intricately folded apical rhabdomere membranes of photoreceptor neurons and the postsynaptic density of glutamatergic neuromuscular junctions. Flies that lack all Amphiphysin function are viable, lack a
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Petrie, Emma J., Richard W. Birkinshaw, Akiko Koide, et al. "Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies." Proceedings of the National Academy of Sciences 117, no. 15 (2020): 8468–75. http://dx.doi.org/10.1073/pnas.1919960117.

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The necroptosis cell death pathway has been implicated in host defense and in the pathology of inflammatory diseases. While phosphorylation of the necroptotic effector pseudokinase Mixed Lineage Kinase Domain-Like (MLKL) by the upstream protein kinase RIPK3 is a hallmark of pathway activation, the precise checkpoints in necroptosis signaling are still unclear. Here we have developed monobodies, synthetic binding proteins, that bind the N-terminal four-helix bundle (4HB) “killer” domain and neighboring first brace helix of human MLKL with nanomolar affinity. When expressed as genetically encode
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Parodi, Emily M., Crystal S. Baker, Cayla Tetzlaff, Sasha Villahermosa, and Linda S. Huang. "SPO71 Mediates Prospore Membrane Size and Maturation in Saccharomyces cerevisiae." Eukaryotic Cell 11, no. 10 (2012): 1191–200. http://dx.doi.org/10.1128/ec.00076-12.

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ABSTRACT The mechanisms that control the size and shape of membranes are not well understood, despite the importance of these structures in determining organelle and cell morphology. The prospore membrane, a double lipid bilayer that is synthesized de novo during sporulation in S. cerevisiae , grows to surround the four meiotic products. This membrane determines the shape of the newly formed spores and serves as the template for spore wall deposition. Ultimately, the inner leaflet of the prospore membrane will become the new plasma membrane of the cell upon germination. Here we show that Spo71
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Mc Dermott, Ray, Umit Ziylan, Danièle Spehner, et al. "Birbeck Granules Are Subdomains of Endosomal Recycling Compartment in Human Epidermal Langerhans Cells, Which Form Where Langerin Accumulates." Molecular Biology of the Cell 13, no. 1 (2002): 317–35. http://dx.doi.org/10.1091/mbc.01-06-0300.

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Birbeck granules are unusual rod-shaped structures specific to epidermal Langerhans cells, whose origin and function remain undetermined. We investigated the intracellular location and fate of Langerin, a protein implicated in Birbeck granule biogenesis, in human epidermal Langerhans cells. In the steady state, Langerin is predominantly found in the endosomal recycling compartment and in Birbeck granules. Langerin internalizes by classical receptor-mediated endocytosis and the first Birbeck granules accessible to endocytosed Langerin are those connected to recycling endosomes in the pericentri
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Wilson, D. W., S. W. Whiteheart, M. Wiedmann, M. Brunner, and J. E. Rothman. "A multisubunit particle implicated in membrane fusion." Journal of Cell Biology 117, no. 3 (1992): 531–38. http://dx.doi.org/10.1083/jcb.117.3.531.

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The N-ethylmaleimide sensitive fusion protein (NSF) is required for fusion of lipid bilayers at many locations within eukaryotic cells. Binding of NSF to Golgi membranes is known to require an integral membrane receptor and one or more members of a family of related soluble NSF attachment proteins (alpha-, beta-, and gamma-SNAPs). Here we demonstrate the direct interaction of NSF, SNAPs and an integral membrane component in a detergent solubilized system. We show that NSF only binds to SNAPs in the presence of the integral receptor, resulting in the formation of a multisubunit protein complex
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Boyd, RB, JP Burke, J. Atkin, VW Thompson, and JF Nugent. "Significance of capillary basement membrane changes in diabetes mellitus." Journal of the American Podiatric Medical Association 80, no. 6 (1990): 307–13. http://dx.doi.org/10.7547/87507315-80-6-307.

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Diabetes mellitus is a disease in which the capillary basement membranes are substantially altered. This diabetic microangiopathy is characterized by a thickening of the basement membrane and changes in its permeability characteristic due to a disturbance in the production and distribution of its functional components. Glucose metabolism and insulin imbalance have been implicated in these basement membrane modifications. The authors describe normal capillary basement membrane architecture and then discuss how pathologic changes caused by diabetes mellitus are related to diabetic foot pathology
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GILLOOLY, David J., Anne SIMONSEN, and Harald STENMARK. "Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins." Biochemical Journal 355, no. 2 (2001): 249–58. http://dx.doi.org/10.1042/bj3550249.

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PtdIns3P is a phosphoinositide 3-kinase product that has been strongly implicated in regulating membrane trafficking in both mammalian and yeast cells. PtdIns3P has been shown to be specifically located on membranes associated with the endocytic pathway. Proteins that contain FYVE zinc-finger domains are recruited to PtdIns3P-containing membranes. Structural information is now available concerning the interaction between FYVE domains and PtdIns3P. A number of proteins have been identified which contain a FYVE domain, and in this review we discuss the functions of PtdIns3P and its FYVE-domain-c
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Dissertations / Theses on the topic "Membrane implicite"

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Lanrezac, André. "Interprétation de données expérimentales par simulation et visualisation moléculaire interactive." Electronic Thesis or Diss., Université Paris Cité, 2023. http://www.theses.fr/2023UNIP7133.

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L'objectif de l'approche des simulations moléculaires interactive (Interactive Molecular Simulations - IMS) est d'observer en direct la dynamique conformationnelle d'une simulation moléculaire en cours. Le retour visuel instantané permet un suivi instructif ainsi que l'observation des changements structurels imposés par la manipulation de l'IMS par l'utilisateur. J'ai mené une étude approfondie des connaissances pour rassembler et synthétiser l'ensemble des recherches qui ont développé l'IMS. La dynamique moléculaire interactive (Interactive Molecular Dynamics - IMD) est l'un des premiers prot
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Lekostaj, Jacqueline K. "Molecular analysis of membrane transporters implicated in drug resistance." Connect to Electronic Thesis (ProQuest) Connect to Electronic Thesis (CONTENTdm), 2008. http://worldcat.org/oclc/436214303/viewonline.

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Mesquita, Arthur Dias. "Uma formulação do Método dos Elementos Finitos aplicada à análise elastoplástica de cascas." Universidade de São Paulo, 1998. http://www.teses.usp.br/teses/disponiveis/18/18134/tde-22032018-120500/.

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Um elemento finito para análises elastoplásticas de placas (em flexão ou não) e cascas é descrito. Este elemento apresenta geometria triangular e é o resultado do acoplamento entre um elemento de flexão de placas (DKT) e um elemento de tensão plana, baseado na formulação livre (FF). O elemento DKT é um elemento finito bem conhecido, considerado por muitos autores como um dos melhores de sua classe. O elemento FF apresenta o grau de liberdade rotacional normal, que é essencial quando se trabalha com cascas aproximadamente planas. Além disso, sua convergência é garantida devido à imposição do \'
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Gouguet, Paul. "Deciphering the proteic partners of REMORIN, a membrane-raft phosphoprotein implicated in plant cell-to-cell communication." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0418.

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Les REMORINES du groupe 1 sont des protéines spécifiques des plantes, localisées dans la membrane plasmique. Nous avons montré que StREM1.3 (REM) constitue un marqueur des radeaux lipidiques, des domaines membranaires du plasmalemme enrichis en stérols et sphingolipides. De plus, REM se trouve enrichie dans les plasmodesmes (PD), des canaux ancrés dans la paroi qui assurent les communications intercellulaires. Nous avons mis en évidence pour la première fois le rôle physiologique de REM dans la plante, cette protéine est capable de ralentir la propagation virale du Potato Virus X (PVX) et d’au
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Liu, Yi. "Calcium-related fungal genes implicated in arbuscular mycorrhiza." Phd thesis, Université de Bourgogne, 2012. http://tel.archives-ouvertes.fr/tel-00985826.

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Fluctuations in intracellular (Ca2+) calcium levels generate signaling events and regulate different cellular processes. Whilst the implication of Ca2+ in plant cell responses during arbuscular mycorrhiza (AM) interactions is well documented, nothing is known about the regulation or role of this secondary meesenger in the fungal symbiont. The molecular basis of fungal calcium homeostasis in the AM symbiosis was analyzed by investigating the expression of Ca2+-related fungal genes. In a first study, G. mosseae genes putatively encoding a MAP3k-like protein kinase (Gm2) and a P-type ATPase (Gm15
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Canu, Stéphane. "La continuation appliquée aux modèles biologiques." Compiègne, 1986. http://www.theses.fr/1986COMPI237.

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Silva, Nancy Fonseca. "The characterization of PERK1 a novel receptor kinase implicated in plant defense and development /." 2003. http://wwwlib.umi.com/cr/yorku/fullcit?pNQ82822.

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Thesis (Ph. D.)--York University, 2003. Graduate Programme in Biology.<br>Typescript. Includes bibliographical references (leaves 192-219). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pNQ82822.
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Books on the topic "Membrane implicite"

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Shier, Peter. Purification of a plasma membrane glycoprotein implicated in cell sorting in dictyostelium discoideum. 1987.

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Johnson, Elizabeth M. Hyaline moulds. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0017.

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Hyaline moulds are fungi that grow predominantly in a filamentous form with colourless hyphae. This is not a taxonomic grouping and encompasses many thousands of different fungal genera. However, there is a small subset of environmental saprobes or plant pathogenic moulds, currently comprising at least 75 species from 30 different genera, that are opportunistic human pathogens and have been implicated in invasive infections referred to as hyalohyphomycosis. In addition they may cause less invasive cutaneous, subcutaneous, mucous membrane, and corneal infections. This group of organisms include
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Heidet, Laurence, Bertrand Knebelmann, and Marie Claire Gubler. Alport syndrome. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0323.

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The diagnosis of Alport syndrome is suspected from the clinical features and confirmed by identifying the almost pathognomonic ultrastructural changes to the basement membrane in a family member with early disease (so that glomeruli are not too sclerosed), or in modern times by identifying a causative mutation in one or more of the three implicated COL4 genes. Genetic testing is becoming simpler and cheaper, but is still out of the reach of many. Eighty-five per cent of cases are caused by COL4A5 mutations and 10–15% by autosomal recessive disease. A significant proportion of morbidity in X-li
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Cattran, Daniel C., and Heather N. Reich. Membranous glomerulonephritis. Edited by Neil Turner. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0064_update_001.

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It has been clear for several decades from comparison with the rodent model disease Heymann nephritis that membranous glomerulonephritis (MGN) is an immune condition in which antibodies, usually autoantibodies, bind to targets on the surface of podocytes. However, the antigen in Heymann nephritis, megalin, is not present on human podocytes. The first potential antigen was identified by studying rare examples of maternal alloimmunization, leading to congenital membranous nephropathy in the infant caused by antibodies to neutral endopeptidase. More recently, the target of autoantibody formation
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Book chapters on the topic "Membrane implicite"

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Feig, Michael. "Implicit Membrane Models for Membrane Protein Simulation." In Methods in Molecular Biology. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-177-2_10.

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Auger, Denise, Pam Bounelis, and Richard B. Marchase. "Phosphoglucomutase is a Cytoplasmic Glycoprotein Implicated in the Regulated Secretory Pathway." In Molecular Mechanisms of Membrane Traffic. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-662-02928-2_52.

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Uguz, A. Cihangir. "The Role of Ion Channels in Diabetes Mellitus." In Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism. Nobel Tip Kitabevleri, 2023. http://dx.doi.org/10.69860/nobel.9786053359104.11.

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The role of ion channels in diabetes mellitus encompasses their critical involvement in regulating cellular functions central to glucose metabolism and insulin secretion. Ion channels, such as potassium (K+) channels and calcium (Ca2+) channels, play pivotal roles in pancreatic beta cells where they govern insulin secretion in response to changes in blood glucose levels. ATP-sensitive K+ channels (KATP channels) mediate glucose-stimulated insulin secretion by modulating cell membrane potential and calcium influx, essential for triggering insulin release. Dysfunction or dysregulation of these i
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Park, Joshua K., Nathan J. Coffey, Aaron Limoges, and Anne Le. "The Heterogeneity of Lipid Metabolism in Cancer." In The Heterogeneity of Cancer Metabolism. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65768-0_3.

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AbstractThe study of cancer cell metabolism has traditionally focused on glycolysis and glutaminolysis. However, lipidomic technologies have matured considerably over the last decade and broadened our understanding of how lipid metabolism is relevant to cancer biology [1–3]. Studies now suggest that the reprogramming of cellular lipid metabolism contributes directly to malignant transformation and progression [4, 5]. For example, de novo lipid synthesis can supply proliferating tumor cells with phospholipid components that comprise the plasma and organelle membranes of new daughter cells [6, 7
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Ventura, Raúl, and María Isabel Hernández-Alvarez. "Endoplasmic Reticulum: A Hub in Lipid Homeostasis." In Updates on Endoplasmic Reticulum [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105450.

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Endoplasmic Reticulum (ER) is the largest and one of the most complex cellular structures, indicating its widespread importance and variety of functions, including synthesis of membrane and secreted proteins, protein folding, calcium storage, and membrane lipid biogenesis. Moreover, the ER is implicated in cholesterol, plasmalogen, phospholipid, and sphingomyelin biosynthesis. Furthermore, the ER is in contact with most cellular organelles, such as mitochondria, peroxisomes, Golgi apparatus, lipid droplets, plasma membrane, etc. Peroxisomes are synthesized from a specific ER section, and they
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Grossfield, Alan. "Chapter 5 Implicit Modeling of Membranes." In Current Topics in Membranes. Elsevier, 2008. http://dx.doi.org/10.1016/s1063-5823(08)00005-7.

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Robinson, Margaret S. "Adaptor proteins (AP-1-AP-3)." In Guidebook to the Cytoskeletal and Motor Proteins. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780198599579.003.00147.

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Abstract The ADP-ribosylation factors (Arf) are a family of 21 kDa GTP binding proteins which have been implicated as regulators of a wide variety of vesicular transport steps, as structural components of non-clathrin (COP!) coated vesicles and as direct activators of phospholipase D (PLD1). Activation of Arfs, coincident with the binding of GTP, causes a translocation of the otherwise soluble protein to membranes and is proposed to result in the nucleation of coat protein assembly and vesicular budding. Apparently conflicting data currently lead to uncertainty regarding the role of (Arf sensi
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Carraway, Coralie A. Carothers, and Kermjt I. Carraway. "Signalling complexes: association of signalling proteins with the cytoskeleton." In Cytoskeleton: signalling and cell regulation. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780199637829.003.0004.

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Abstract A plethora of studies in the areas of membranes, cytoskeleton and. more recently. signal transduction have contributed to both concepts and technologies for the study of interactions of signalling proteins with the cytoskeleton (for overviews. see refs 1 and 2). These studies have implicated association of signalling proteins with the membrane and with the cytoskeleton in targeting these proteins to appropriate cellular loc,11ions for their participation in signal transduction events. Appropriate cellular localization is requisite for activation processes (3) and can occur reversibly.
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Cheney, Richard E. "Myosin V." In Guidebook to the Cytoskeletal and Motor Proteins. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780198599579.003.00133.

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Abstract The class V myosins are an abundant and widely distributed group of motor proteins implicated in organelle trafficking and membrane targeting. They appear to form two-headed dimers that are joined by a stalk to a globular tail domain of unknown function. A combination of biochemical and molecular genetic studies has led to the hypothesis that class V myosins may function as actin-based motors for organelle transport.
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Gu, Anyu, Chikezie O. Madu, and Yi Lu. "Perspective Chapter: Role of Cancer-Associated Fibroblasts in Oncogenesis." In Tumor Microenvironment - New Insights [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.108832.

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The tumor microenvironment consists of multiple types of cells, including endothelial cells, pericytes, neutrophil macrophage mast cells, lymphatic cells, basement membrane extracellular matrix, as well as fibroblasts. Fibroblasts populations found in cancers, also known as cancer-associated fibroblasts, have been implicated in the initiation, progression, and metastasis of tumors. This chapter will focus on the roles of cancer-associated fibroblasts in the progression of cancer and the studies of use of cancer-associated fibroblasts as a therapeutic target for cancer intervention.
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Conference papers on the topic "Membrane implicite"

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Gordnier, Raymond E., and Peter J. Attar. "Implicit LES Simulations for an Aspect Ratio Two Flexible Membrane Wing." In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajk2011-08008.

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Development of an aeroelastic solver with application to flexible membrane wings for micro air vehicle applications is presented. A high-order (up to 6th order) Navier-Stokes solver is coupled with a geometrically nonlinear p-version Reissner-Mindlin finite element plate model to simulate the highly flexible elastic membrane. An implicit LES approach is employed to compute the mixed laminar/transitional/turbulent flowfields present for the low Reynolds number flows associated with micro air vehicles. Intitial computations for a baseline rigid membrane wing are presented to understand the compl
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Gordnier, Raymond, and Peter Attar. "Implicit LES Simulations of a Low Reynolds Number Flexible Membrane Wing Airfoil." In 47th AIAA Aerospace Sciences Meeting including The New Horizons Forum and Aerospace Exposition. American Institute of Aeronautics and Astronautics, 2009. http://dx.doi.org/10.2514/6.2009-579.

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Eaton, Brandon, Michael R. von Spakovsky, Michael W. Ellis, Douglas J. Nelson, Benoit Olsommer, and Nathan Siegel. "One-Dimensional, Transient Model of Heat, Mass, and Charge Transfer in a Proton Exchange Membrane." In ASME 2001 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/imece2001/aes-23652.

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Abstract A transient, one-dimensional, model of the membrane of a proton exchange membrane fuel cell is presented. The role of the membrane is to transport protons from the anode to cathode of the fuel cell while preventing the transport of other reactants. The membrane is modeled assuming mono-phase, multi-species flow. For water transport, the principle driving forces modeled are a convective force, an osmotic force (i.e. diffusion), and an electric force. The first of these results from a pressure gradient, the second from a concentration gradient, and the third from the migration of proton
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Li, He, and George Lykotrafitis. "Modeling Diffusion and Vesiculation in Defective Human Erythrocyte Membrane." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14203.

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The hemolytic disorders of hereditary spherocytosis (HS) and hereditary elliptocytosis (HE) affect the lives of millions of individuals worldwide. In HS and HE, connections in the vertical and horizontal directions between components of the RBC membrane (see Fig. 1(a)), are disrupted due to defective proteins, leading to loss of the structural and functional integrity of the membrane (1–2). Moreover, disruptions of either the vertical interactions or horizontal interactions affect the lateral diffusivity of the mobile band 3 proteins, as the motion of band 3 in the RBC membrane is confined by
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Gorski, J., L. Van Hove, F. Vanlangendonck, M. A. Boogaerts, R. L. Verwilghen, and J. Vermylen. "PLATELET MEMBRANE GLYCOPROTEINS ABNORMALITIES IN PATIENTS WITH ACUTE LEUKEMIAS AND MALIGNANT LYMPHOMAS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643201.

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Membrane glycoproteins are implicated in platelet functions.In myeloproliferative disorders some of the platelet functions are known to be perturbated and an abnormal glycoproteins pattern was demonstrated ear-lier.In this study flow cytometry analysis of human platelet membrane glycoproteins IIa and IIIa in patients with acute leukemias and malignant lymphomas has been performed using monoclonal antibodies against these glycoproteins.A reduction in number of glycoproteins receptors on platelet membrane was demonstrated in patients with acute leukemias and malignant lymphomas in comparison wit
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OKUZONO, T., K. SAKAGAMI, and A. KATSUYAMA. "AN IMPLICIT TIME-DOMAIN FINITE ELEMENT SCHEME FOR SOUND FIELD ANALYSIS WITH PERMEABLE MEMBRANE ABSORBERS." In ICSV24 2017. Institute of Acoustics, 2024. https://doi.org/10.25144/24625.

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Morss, Alisa, Michael Jonas, and Elazer R. Edelman. "Elevated Basement Membrane Fibroblast Growth Factor-2 Protects Endothelial Cells in High Glucose." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176187.

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Vascular disease is the primary cause of morbidity and mortality in diabetics. Diabetic vascular disease is disseminated and includes renal capillary hypertrophy, reduced wound repair, impaired angiogenesis, and rapid and excessive hyperplasia after endovascular intervention [1, 2]. No single biochemical aberration unifies the diffuse nature of diabetic vascular disease. Hyperglycemia has been implicated, and yet glucose effects persist long after restoration of euglycemia. It is possible that acute fluctuations in glucose concentration have prolonged cell and tissue effects.
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Gordnier, Raymond E., and Peter J. Attar. "Impact of Flexibility on the Aerodynamics of an Aspect Ratio Two Membrane Wing." In ASME 2012 Fluids Engineering Division Summer Meeting collocated with the ASME 2012 Heat Transfer Summer Conference and the ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/fedsm2012-72296.

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Development of an aeroelastic solver with application to flexible membrane wings for micro air vehicles is presented. A high-order (up to 6th order) Navier-Stokes solver is coupled with a geometrically nonlinear p-version Reissner-Mindlin finite element plate model to simulate the highly flexible elastic membrane. An implicit LES approach is employed to compute the mixed laminar/transitional/turbulent flowfields present for the low Reynolds number flows associated with micro air vehicles. Computations are performed for an aspect ratio two membrane wing at angles of attack α = 10°, 16° and 23°
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Asijee, G. M., T. Bruin, A. Sturk, J. E. ten Cate, and L. Muszbek. "VINCULIN ISOFORMS IN HUMAN BLOOD PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643902.

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In several cells vinculin has been implicated in the interaction between the cytoskeleton and the outer ceil membrane. We have recently demonstrated that vinculin becomes associated with the Triton X-100 insoluble cytoskeleton of blood platelets upon thrombin-induced activation (Asijee et al, Exp Cell Res, 1987, in press). In the present study we demonstrate by SDS-PAGE and immunoblotting that vinculin is also present in the membrane skeleton of both non-activated and activated human blood platelets. The membrane skeleton was prepared by the method of Fox (J Clin Invest, 1985: 76, 1673), and p
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Giltay, J. C., O. C. Leeksma, A. E. G. Kr v. d. Borne, and J. A. van Mourik. "THE PLATELET ALLOANTIGEN Zwa (P1A1) IS EXPRESSED BY CULTURED ENDOTHELIAL CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642812.

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Zwa (P1A1) is a platelet specific alloantigen, located on glycoprotein (GP) IIIa, and is of pathogenic importance in alloimmunologic disorders such as neonatal alloimmune thrombocytopenia and post transfusion purpura. As endothelial cells synthesize a plasma membrane protein complex which is structurally closely related to the platelet membrane GP IIb/IIIa complex, we examined whether these cells also express Zwa. Employing a variety of immunochemical techniques, our studies show that endothelial cells indeed can express this antigen at the plasma membrane surface.We also compared the expressi
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Reports on the topic "Membrane implicite"

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Chen, Junping, Zach Adam, and Arie Admon. The Role of FtsH11 Protease in Chloroplast Biogenesis and Maintenance at Elevated Temperatures in Model and Crop Plants. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699845.bard.

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specific objectives of this proposal were to: 1) determine the location, topology, and oligomerization of FtsH11 protease; 2) identify the substrate/s of FtsH11 and the downstream components involved in maintaining thermostability of chloroplasts; 3) identify new elements involved in FtsH11 protease regulatory network related to HT adaptation processes in chloroplast; 4) Study the role of FtsH11 homologs from crop species in HT tolerance. Background to the topic: HT-tolerant varieties that maintain high photosynthetic efficiency at HT, and cope better with daily and seasonal temperature fluctu
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Christopher, David A., and Avihai Danon. Plant Adaptation to Light Stress: Genetic Regulatory Mechanisms. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7586534.bard.

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Original Objectives: 1. Purify and biochemically characterize RB60 orthologs in higher plant chloroplasts; 2. Clone the gene(s) encoding plant RB60 orthologs and determine their structure and expression; 3. Manipulate the expression of RB60; 4. Assay the effects of altered RB60 expression on thylakoid biogenesis and photosynthetic function in plants exposed to different light conditions. In addition, we also examined the gene structure and expression of RB60 orthologs in the non-vascular plant, Physcomitrella patens and cloned the poly(A)-binding protein orthologue (43 kDa RB47-like protein).
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Wisniewski, Michael, Samir Droby, John Norelli, Dov Prusky, and Vera Hershkovitz. Genetic and transcriptomic analysis of postharvest decay resistance in Malus sieversii and the identification of pathogenicity effectors in Penicillium expansum. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597928.bard.

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Use of Lqh2 mutants (produced at TAU) and rNav1.2a mutants (produced at the US side) for identifying receptor site-3: Based on the fact that binding of scorpion alpha-toxins is voltage-dependent, which suggests toxin binding at the mobile voltage-sensing region, we analyzed which of the toxin bioactive domains (Core-domain or NC-domain) interacts with the DIV Gating-module of rNav1.2a. This analysis was based on the assumption that the dissociation of toxin mutants upon depolarization would vary from that of the unmodified toxin should the substitutions affect a site of interaction with the ch
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