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Robinson, Kim. "A Whole-school Approach … with a Healthy Dose of Student leadership! Melba High School." Australian Journal of Guidance and Counselling 14, no. 1 (July 2004): 106–8. http://dx.doi.org/10.1017/s1037291100002703.
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Zaniewicz-Bajkowska, Anna, Jolanta Franczuk, and Edyta Kosterna. "Effect of foliar feeding on yield and fruit quality of three melon (Cucumis melo L.) cultivars." Folia Horticulturae 21, no. 2 (December 1, 2009): 65–75. http://dx.doi.org/10.2478/fhort-2013-0139.
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Abstract The effect of foliar feeding with two fluid multicomponent fertilizers was investigated: Florovit and Ekolist Warzywa + Urea on the yield and quality of three medium-fruit-size melon cultivars (‘Charentais F1’, ‘Melba’, ‘Fiesta’). Weather conditions in the consecutive years of the study had a significant influence on the yield level and quality of fruit. A higher yield of better quality was achieved in the years 2005 and 2007. That period was characterised by relatively high air temperature and low rainfall towards the end of the growing period of melon. The fertilizers applied in the experiment significantly influenced melon yielding. The plants fertilized with Ekolist Warzywa + Urea provided a higher marketable yield of melon fruit than the plants fertilized with Florovit. When applied, this fertilizer also caused an increase in flesh thickness and fruit flavour as compared with Florovit feeding. Foliar feeding with both studied patterns increased the average fruit weight and number of marketable fruit as compared to the non-fertilized treatment. Among the studied cultivars, ‘Fiesta’ gave the highest marketable yield and the best quality fruit.
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Ulyanovskaya, Elena, and Evgenia Belenko. "Using the genetic diversity of the Malus genus to solve the priority areas of breeding." BIO Web of Conferences 25 (2020): 02001. http://dx.doi.org/10.1051/bioconf/20202502001.
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The breeding use of the most valuable species and interspecies forms of fruit plants remains currently the most important biological resource for creating the varieties with increased adaptability to the complex of abioand biotic stressors of the environment, improved biochemical composition of fruits and with other important features for breeding. The results of a long-term study (2005-2019) of interspecific hybrid forms of apple-tree-representatives of the Malus genus, growing in the North Caucasus Region of Russia are presented. The aim of the study is to identify the most rapid and productive interspecific hybrid forms of apple-tree with polygenic and oligogenic types of scab resistance (Venturia inaequalis (Cook) G. Winter). Modern breeding programs and methods were used. We have identified the early-fruiting interspecies apple forms created with the participation of the summer Melba variety, the species of M. purpurea. It is allocated the elite and selected apple forms resistant to scab with a high average yield (29.03-40.03 t/ha), high indicators of total yield (377.27-520.33 t/he) from hybrid families with the participation of species: M. atrosanguinea 804/240-57, M. floribunda 821, M. purpurea and the large-fruited form No. 62 (created with the participation of Golden Delicious 4x, Wolf River, M. atrosanguinea 804/240-57) with fruits of 202.3 g an average weight.
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Mohammed Fazil Ahmed, Mohammed Fazil Ahmed, and A. Srinivasa Rao. "Simultaneous Determination of Phenolic Compounds in Melia Azedarach. Linn Leaves by High-Performance Liquid Chromatography." Indian Journal of Applied Research 3, no. 11 (October 1, 2011): 429–31. http://dx.doi.org/10.15373/2249555x/nov2013/137.
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Goswami, Manika, Shikha Bhagta, and Dushyant Sharma. "Melia dubia and its Importance: A Review." International Journal of Economic Plants 7, no. 1 (February 28, 2020): 029–33. http://dx.doi.org/10.23910/2/2020.0351.
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Melia dubia popularly known as Malabar Neem is a promising multipurpose tree highly suitable for farm forestry and agro forestry for generating higher income per unit area. Melia dubia is one of the fastest growing trees in the world and considered as a money spinning tree of short rotation due to its high demand in pulpwood, plywood and timber industries. It is a good fuel and fodder yielding tree. In addition to this, Melia dubia also has extensive medicinal, pharmacological, ethnomedicinal and conventional properties and uses. The current article reviews literature on importance of Melia dubia for timber industry and medicinal value.
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LaFlair, Geoffrey T., and Shelley Staples. "Using corpus linguistics to examine the extrapolation inference in the validity argument for a high-stakes speaking assessment." Language Testing 34, no. 4 (September 19, 2017): 451–75. http://dx.doi.org/10.1177/0265532217713951.
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Investigations of the validity of a number of high-stakes language assessments are conducted using an argument-based approach, which requires evidence for inferences that are critical to score interpretation (Chapelle, Enright, & Jamieson, 2008b; Kane, 2013). The current study investigates the extrapolation inference for a high-stakes test of spoken English, the Michigan English Language Assessment Battery (MELAB) speaking task. This inference requires evidence that supports the inferential step from observations of what test takers can do on an assessment to what they can do in the target domain (Chapelle et al., 2008b; Kane, 2013). Typically, the extrapolation inference has been supported by evidence from a criterion measure of language ability. This study proposes an additional empirical method, namely corpus-based register analysis (Biber & Conrad, 2009), which provides a quantitative framework for examining the linguistic relationship between performance assessments and the domains to which their scores are extrapolated. This approach extends Bachman and Palmer’s (2010) focus on the target language use (TLU) domain analysis in their study of assessment use arguments by providing a quantitative approach for the study of language. We first explain the connections between corpus-based register analysis and TLU analysis. Second, an investigation of the MELAB speaking task compares the language of test-taker responses to the language of academic, professional, and conversational spoken registers, or TLU domains. Additionally, the language features at different performance levels within the MELAB speaking task are investigated to determine the relationship between test takers’ scores and their language use in the task. Following previous studies using corpus-based register analysis, we conduct a multi-dimensional (MD) analysis for our investigation. The comparison of the language features from the MELAB with the language of TLU domains revealed that support for the extrapolation inference varies across dimensions of language use.
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Lemmetty, A., M. Soukainen, and T. Tuovinen. "First Report of ‘Candidatus Phytoplasma mali,’ the Causal Agent of Apple Proliferation Disease, in Apple Trees in Finland." Plant Disease 97, no. 10 (October 2013): 1376. http://dx.doi.org/10.1094/pdis-04-13-0397-pdn.
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Based on an earlier survey of putative psyllid vectors of apple proliferation (AP), carried out in 2009 and 2010, Cacopsylla picta (Förster) populations infected with ‘Candidatus Phytoplasma mali’ were detected in at least two commercial apple (Malus domestica Borkh.) orchards in southern Finland (1). To establish the presence of ‘Ca. P. mali’ in apple trees, a survey was conducted in 17 commercial apple orchards in August 2012. Phytosanitary inspectors tracked the source of the ‘Ca. P. mali’ by collecting 33 leaf samples from trees showing probable symptoms. Typical symptoms, including elongated stipules and witches' broom, were rare. Total DNA was extracted from leaves using a DNeasy Plant Mini Kit (Qiagen, Hilden, Germany) and screened for ‘Ca. P. mali’ with real-time PCR (2) and the commercial Apple Proliferation Group – complete PCR reaction kit (Loewe Biochemica GmbH, Sauerlach, Germany). Two samples tested positive and results were confirmed with TaqMan PCR and conventional PCR assays and DNA sequencing in the Food and Environment Research Agency (Fera), in the United Kingdom. One positive sample was taken from an orchard in Lohja, southern Finland, where high ‘Ca. P. mali’ incidence in overwintered C. picta was observed in 2010 (1). ‘Ca. P. mali’ was found in a >40-year-old ‘Red Melba’ tree with witches' broom but without elongated stipule symptoms. The other positive sample was collected from an orchard in the Aland Islands, where the infected ‘Lobo’ tree showed symptoms of elongated stipules. This orchard was not monitored for AP vectors. No small fruit symptoms were noted by inspectors or growers in either of the orchards. The positive samples were further analyzed for subtypes using PCR/RFLP and primers AP13/AP10 (3). The amplicons (776 bp) were sequenced and digested with HincII and BspHI (New England BioLabs Inc., Ipswich, MA) following manufacturer's instructions. Both samples proved to be apple proliferation subtypes AT-1 on the basis of RFLP and the sequenced 776-bp region. Sequences of the 776-bp amplicon of the Lohja and Aland isolates showed 100% and 99% identity, respectively, with sequences of apple proliferation isolates (accession nos. L22217.1 and CU469464.1) in GenBank. Both suspected psyllid vectors of ‘Ca. P. mali’ C. picta and C. melanoneura (Förster) occur in Finland, but their distribution, abundance, and transmission specificity is inadequately documented. The next step to evaluate the risk of spread of apple proliferation in commercial orchards is an extensive survey of the occurrence of Cacopsylla species infected with ‘Ca. P. mali’. References: (1) A. Lemmetty et al. B. Insectol. 64:257, 2011. (2) P. Nikolić et al. Mol. Cell. Probes. 24:303, 2010. (3) W. Jarausch et al. Mol. Cell. Probes 14:17, 2000.
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Rehman, Khushnoodur, Muhammad Hamayun, Sumera Afzal Khan, Amjad Iqbal, and Anwar Hussain. "Heavy Metal Analysis of Locally Available Anticancer Medicinal Plants." Biosciences, Biotechnology Research Asia 16, no. 1 (March 26, 2019): 105–11. http://dx.doi.org/10.13005/bbra/2727.
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Plant species are used in different forms either dry or fresh to extract the active ingredients that can be used for medicinal purposes. These active ingredients may or may not contain non-essential elements. One of the main non-essential elements includes heavy metals. The consumption of medicinal plants having larger amounts of heavy metals can affect the health of human beings. Currently, we have also assessed eight locally available medicinal plant species for endogenous heavy metals (i.e. cadmium, arsenic, mercury, lead and zinc). The results revealed that Saxifraga flagellaris, Moringa oleifera, and Fegonia cretica had no lead, whereas Melia azedarach had the highest concentration of lead. Similarly, Saxifraga flagellaris had lower concentration of arsenic, while Albizia lebbeck had zero and Melia azedarach had the highest accumulation of arsenic. Cadmium was absent in Saxifraga flagellaris, Withania coagulans, and Valeriana jatamansi. Moringa oleifera had lower and Melia azedarach had the greatest amounts of cadmium. Mercury concentration has been high in Melia azedarach (2.39±0.18 µg/g), followed by Hedera helix (0.26±0.02 µg/g), Saxifraga flagellaris (0.051±0.031 µg/g) and Albizia lebbeck (0.041±0.01 µg/g). The species, Fegonia cretica, Valeriana jatamansi, Withania coagulans, Moringa oleifera had no mercury. The highest zinc concentration was observed in Melia azedarach and the lowest concentration was found in Saxifraga flagellaris.
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Jaoko, Victor, Clauvis Nji Tizi Taning, Simon Backx, Jackson Mulatya, Jan Van den Abeele, Titus Magomere, Florence Olubayo, Sven Mangelinckx, Stefaan P. O. Werbrouck, and Guy Smagghe. "The Phytochemical Composition of Melia volkensii and Its Potential for Insect Pest Management." Plants 9, no. 2 (January 22, 2020): 143. http://dx.doi.org/10.3390/plants9020143.
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Due to potential health and environmental risks of synthetic pesticides, coupled with their non-selectivity and pest resistance, there has been increasing demand for safer and biodegradable alternatives for insect pest management. Botanical pesticides have emerged as a promising alternative due to their non-persistence, high selectivity, and low mammalian toxicity. Six Meliaceae plant species, Azadirachta indica, Azadirachta excelsa, Azadirachta siamens, Melia azedarach, Melia toosendan, and Melia volkensii, have been subject to botanical pesticide evaluation. This review focuses on Melia volkensii, which has not been intensively studied. M. volkensii, a dryland tree species native to East Africa, has shown activity towards a broad range of insect orders, including dipterans, lepidopterans and coleopterans. Its extracts have been reported to have growth inhibiting and antifeedant properties against Schistocerca gregaria, Trichoplusia ni, Pseudaletia unipuncta, Epilachna varivestis, Nezara viridula, several Spodoptera species and other insect pests. Mortality in mosquitoes has also been reported. Several limonoids with a wide range of biological activities have been isolated from the plant, including volkensin, salannin, toosendanin, trichilin-class limonoids, volkendousin, kulactone among others. This paper presents a concise review of published information on the phytochemical composition and potential of M. volkensii for application in insect pest management.
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Jin, Xiaowei, Charlotte von Gall, Rick L. Pieschl, Valentin K. Gribkoff, Jorg H. Stehle, Steven M. Reppert, and David R. Weaver. "Targeted Disruption of the Mouse Mel1b Melatonin Receptor." Molecular and Cellular Biology 23, no. 3 (February 1, 2003): 1054–60. http://dx.doi.org/10.1128/mcb.23.3.1054-1060.2003.
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ABSTRACT Two high-affinity, G protein-coupled melatonin receptor subtypes have been identified in mammals. Targeted disruption of the Mel1a melatonin receptor prevents some, but not all, responses to the hormone, suggesting functional redundancy among receptor subtypes (Liu et al., Neuron 19:91-102, 1997). In the present work, the mouse Mel1b melatonin receptor cDNA was isolated and characterized, and the gene has been disrupted. The cDNA encodes a receptor with high affinity for melatonin and a pharmacological profile consistent with its assignment as encoding a melatonin receptor. Mice with targeted disruption of the Mel1b receptor have no obvious circadian phenotype. Melatonin suppressed multiunit electrical activity in the suprachiasmatic nucleus (SCN) in Mel1b receptor-deficient mice as effectively as in wild-type controls. The neuropeptide, pituitary adenylyl cyclase activating peptide, increases the level of phosphorylated cyclic AMP response element binding protein (CREB) in SCN slices, and melatonin reduces this effect. The Mel1a receptor subtype mediates this inhibitory response at moderate ligand concentrations (1 nM). A residual response apparent in Mel1a receptor-deficient C3H mice at higher melatonin concentrations (100 nM) is absent in Mel1a-Mel1b double-mutant mice, indicating that the Mel1b receptor mediates this effect of melatonin. These data indicate that there is a limited functional redundancy between the receptor subtypes in the SCN. Mice with targeted disruption of melatonin receptor subtypes will allow molecular dissection of other melatonin receptor-mediated responses.
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Gupta, LN, Ram Avtar, Ameerjeet Singh, Pankaj Kumar, Emmanuel Mutisya, Geetha Mohan, and GS Gupta. "Assessment of Ganges River Water Quality at Allahabad: A case study for the event of Magha Mela." International Journal of Life Sciences 8, no. 3 (May 27, 2014): 8–14. http://dx.doi.org/10.3126/ijls.v8i3.9303.
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Considering Ganga River as one of main Holy River in India, millions of people throng to the river to have a holy dip, Aachman (Mouthful of holy water) and cleanse themselves of sins. Magh Mela is a great festival to take place in bank of Triveni (Sangam) at Allahabad and runs more than one and half month, when millions of pilgrims from different regions in India go there for taking a holy bath in Sangam of Ganga. Thus, the bathing in the river during Magh Mela leads to high pollution of the river in comparison to other days such as normal bathing days. This study focused on the water quality status from some selected physico-chemical parameters of River Ganges and the impact of Magh Mela as well as the variation in the river’s flow rate. Results indicate that the pollution load was alarmingly high and the flow of the Ganga had been very poor. Further, the study found that the water was not fit for bathing during the 2012 Magh Mela. DOI: http://dx.doi.org/10.3126/ijls.v8i3.9303 International Journal of Life Sciences Vol.8(3): 2014: 8-14
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Silvestroni, Aurelio, Cristelle Connes, Fernando Sesma, Graciela Savoy de Giori, and Jean-Christophe Piard. "Characterization of the melA Locus for α-Galactosidase in Lactobacillus plantarum." Applied and Environmental Microbiology 68, no. 11 (November 2002): 5464–71. http://dx.doi.org/10.1128/aem.68.11.5464-5471.2002.
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ABSTRACT Alpha-galactosides are abundant sugars in legumes such as soy. Because of the lack of α-galactosidase (α-Gal) in the digestive tract, humans are unable to digest these sugars, which consequently induce flatulence. To develop the consumption of the otherwise highly nutritional soy products, the use of exogenous α-Gal is promising. In this framework, we characterized the melA gene for α-Gal in Lactobacillus plantarum. The melA gene encodes a cytoplasmic 84-kDa protein whose enzymatically active form occurs as oligomers. The melA gene was cloned and expressed in Escherichia coli, yielding an active α-Gal. We show that melA is transcribed from its own promoter, yielding a monocistronic mRNA, and that it is regulated at the transcriptional level, i.e., it is induced by melibiose but is not totally repressed by glucose. Posttranscriptional regulation by the carbon source could also occur. Upstream of melA, a putative galactoside transporter, designated RafP, was identified that shows high homology to LacS, the unique transporter for both α- and β-galactosides in Streptococcus thermophilus. rafP is also expressed as a monocistronic mRNA. Downstream of melA, the lacL and lacM genes were identified that encode a heterodimeric β-galactosidase. A putative galM gene identified in the same cluster suggests the presence of a galactose operon. These results indicate that the genes involved in galactoside catabolism are clustered in L. plantarum ATCC 8014. This first genetic characterization of melA and of its putative associated transporter, rafP, in a lactobacillus opens doors to various applications both in the manufacture of soy-derived products and in probiotic and nutraceutical issues.
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Ali, Sadik, AnupMaiti, Vishal Kumar Vishwakarma, and Kumar Ajay. "Assessment of Hepatoprotective and Antiulcer Activity of Launaea aspleniifolia Hook in Laboratory Animals." Current Bioactive Compounds 16, no. 5 (July 16, 2020): 703–12. http://dx.doi.org/10.2174/1573407215666190308154713.
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Background: Launaea aspleniifolia Hook (Family Asteraceae) is used traditionally in medicine in Indian system for the treatment of leucoderma. This study was conducted to evaluate the hepatoprotective and antiulcer effects using the methanolic extract of Launaea aspleniifolia Hook (MELA). Methods: The MELA in the dose of 200 and 400 mg/kg body weight (b.w.) was administered orally, daily for 7 days to prevent the acetaminophen-induced hepatotoxicity and peptic ulcer. In order to determine the antioxidant enzymes activity, various enzymatic parameters including alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBL), direct bilirubin (DBL), alkaline phosphatase (ALP), total protein (TP), albumin (ALB), high density lipoproteins (HDL), random glucose test (RBS), serum creatinine levels (SCL) and direct bilirubin (DBL) were determined. Further, the histopathology of tissue and various gastric secretion parameters like free acidity, total acidity ulcer score, % ulcer inhibition, gastric volume, pH, Na+ and K+ and histopathology were determined in PLinduced ulcer model. Results: MELA showed dose-dependent hepatoprotective and ulcer protective effect in acetaminopheninduced hepatotoxicity and antiulcer activity. Furthermore, tissue antioxidant parameter such as reduced Malondialdehyde (MDA), histopathology was also investigated. MELA was more potent in controlling all the serological parameter of liver like ALT, AST, TBL, DBL, ALP, HDL, RBS, SCL, TP and ALB in a dose-dependent manner (P<0.05) induced by Acetaminophen. Apart from this, antiulcer activity MELA was confirmed by the low level of ulcer index along with the reduction of free acidity, total acidity ulcer score, % ulcer inhibition, gastric volume, Na+ and an increase K+, pH of gastric content in a dose-dependent manner (P<0.05) induced PL model. Conclusion: The results indicated a significant dose-dependent effect of MELA from injuries induced in liver and stomach. These protective effects of MELA can be examined in various other toxicities as alone and in combinations.
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Satyawali, Kavita, Sumit Chaturvedi, Neema Bisht, and V. C. Dhyani. "Impact of planting density on wheat crop grown under different tree species in tarai agroforestry system of central himalaya, India." Journal of Applied and Natural Science 10, no. 1 (March 1, 2018): 30–36. http://dx.doi.org/10.31018/jans.v10i1.1573.
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A field trial based Agroforestry system was established at Pantnagar during Rabi season 2012-13 for predicting the effect of spacing on growth and yield of wheat (Triticum aestivum L.) under Eucalyptus camaldulensis and Melia azedarach. The experiment was carried out in split-plot design consisting of two tree species in main plot, viz, Eucalyptus camaldulensis and Melia azedarch and four spacing treatments in sub-plot viz, 3.0m×1.0m, 3.0m×1.5m, 3.0m×2.0m and 3.0m×2.5m with three replications. The wheat crop variety“UP-2338” was sown on December 06, 2012 and harvested on April 27, 2013. Among the tree species, the maximum (15.1 q /ha) and significantly higher grain yield with 21.8% increment was recorded under Melia as compare to Eucalyptus. Whereas, among the different spacings, the wheat growth in terms of dry biomass at 120 DAS (495.4/m2 ), yield attributes and yield in terms of grain (16.0 q/ha), straw (29.4 q/ha) and biological yield (45.4 q/ha) under Melia was significantly higher at 3 × 2.5 m spacing as compared to other planting density. The correlation coefficient (r) studies exhibited that wheat growth and yield attributing characteristics shows significantly (p<0.05) high degree (r=0.75 to 1) positive correlation with each other. The investigation was done to find out the proper planting density for intercropping of wheat with tree species without comprising the wheat growth and enhancing its sustainability.
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Satya Srii, V., N. Nethra, K. Umarani, H. Sowmya, and P. J. Devaraju. "Use of an image analyser to study the imbibition process of Melia dubia seeds." Seed Science and Technology 48, no. 3 (December 31, 2020): 325–32. http://dx.doi.org/10.15258/sst.2020.48.3.01.
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An image analyser system was used to study the process of imbibition in Melia dubia seeds, and in comparison with the conventional method of measuring seed weight by an electronic balance. Melia dudia drupes were divided into three groups and treated accordingly: drupes with intact pericarp, drupes with punctured pericarp and naked seeds without pericarp. Using seed weight and perimeter as parameters, the imbibition process in the seed samples were described by a series of imbibition curves illustrative of the triphasic pattern of water uptake during germination. The image analyser captured small variation in seed parameters between the groups. The sensitivity and feasibility of the advanced method of using an image analyser to investigate individual seeds within a population imply that the image analyser has high potential in advancing seed biology studies.
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Miarsyah, Mieke, Rusdi, Niki Desvidisa Aryani, and Ilmi Zajuli Ichsan. "MEBA: Development Android-based Ecosystem Module for Senior High School Students." Indian Journal of Public Health Research & Development 10, no. 8 (2019): 2114. http://dx.doi.org/10.5958/0976-5506.2019.02168.5.
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Narain, Upma, Arun Kant, and Ashok Kumar Bajaj. "Paronychia: incidence during Magh Mela." International Journal of Advances in Medicine 5, no. 4 (July 23, 2018): 960. http://dx.doi.org/10.18203/2349-3933.ijam20183128.
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Background: Paronychia is one of the most common infections of the fingers and toes. Clinically, paronychia present as an acute or a chronic condition.Methods: The retrospective study was carried out from January 2018 to February 2018 at Allahabad. Gram stain, ZN stain, KOH examination and culture were carried out in 230 cases and species identification was done by Vitek-2 system.Results: Out of these 230 cases 142 (61.73%) presented acute paronychia, 58 (25.21%) cases of chronic paronychia and the remaining 30 cases (13.06%) did not show any growth. In the cases of acute paronychia, authors identified 53.52% Staphylococcus aures, 15.49% Staphylococcus saprophyticus, 2.82% Micrococci and 6.34% Citrobacter among aerobes while among anaerobes authors isolated 5.63% Peptococcus, 8.45% Peptostreptococcus, 3.52% Bacteroides and 4.23% Fusobacterium. Among chronic paronychia authors recorded 48.28% pure bacterial growth, 18.97% pure fungal growth, 20.69% mixed bacterial infections and 12.07% mixed bacterial and fungal infections.Conclusions: From this study authors conclude that cold weather and humidity were the predominant and predisposing factors of the high incidence of acute paronychia. Due to very short span single pathogen was isolated from the lesions. In cases of chronic paronychia 37.76% mixed infection were also recorded which may be due to super aided infections with primary pathogen.
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Narain, Upma, Ashok Kumar Bajaj, and Arun Kant. "Tinea: Incidence during Magh Mela." International Journal of Advances in Medicine 5, no. 4 (July 23, 2018): 993. http://dx.doi.org/10.18203/2349-3933.ijam20183135.
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Background: Dermatophytosis refer to superficial fungal infection of keratinized tissues caused by keratinophilic dermatophytes. It is common in tropics and may present in epidemic proportions in areas with high rates of humidity.Methods: The retrospective study was carried out from January 2018 to February 2018 at Allahabad. Gram stain, KOH examination and culture were carried out in 300 cases.Results: Out of the 300 suspected cases authors identified, 263 cultures tested positive. The macroscopic examination of the scalp, skin and the nails of these 36 patients further revealed 50.20% Tinea corporis, 17.87% Tinea cruris, 11.02 % Tinea mannum, 8.74% Tinea pedis, 7.99% onychomycosis, 3.42% Tinea versicolor and 0.76% Tinea capitis. Culture examinations revealed 52.47% Trychophyton mentagrophyte, 34.98% Trichyopyton rubrum, 3.80% Trychophyton violaceum, 3.43% Malessesia, 2.28% Scopulariopsis brevicaulis, 1.52% Trichophyton verrucosum, 0.76% Microsporum canis and 0.76% Epidermophyton flucossum.Conclusions: The study concludes that in a short period of Magh Mela authors got a large number of skin patients because of their belief that the holiness Ganga water will cure skin problems by itself. Some of the patients were found infected from the beginning and some gather infections during their stay in the mela period. Therefore, a prompt recognition of skin lesions and the identification of these superficial fungi are required for judicious management.
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Kaur, Rajwant, Manpreet Kaur, Avinash Kaur Nagpal, and Jatinder kaur Katnoria. "Polyphenolic characterization of pollen grains of some medicinal plant species using Ultra High Performance Liquid Chromatography (UHPLC)." Journal of Applied and Natural Science 13, no. 3 (September 15, 2021): 840–45. http://dx.doi.org/10.31018/jans.v13i3.2737.
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Polyphenols, the secondary metabolites distributed in different parts of a plant, have major role in protecting the plants from deleterious effects of ultraviolet radiations and various diseases caused by pathogens. Considering the fact that these metabolites possess tremendous medicinal properties, extensive research has been carried out during the past few decades to explore their potential health benefits. Further, polyphenols are documented to possess different activities such as antioxidant, anticarcinogenic, anti-inflammatory, antimicrobial and antiulcer. The present study pertained to analyze different polyphenolic compounds in pollen grains of 9 medicinally important plant species viz., Bauhinia variegata, B.purpurea, Cassia biflora, C. fistula, C. glauca, C. saimea and Delonix regia belonging to Fabaceae family, Hibiscus rosa-sinensis belonging to Malvaceae family and Melia azadirach belonging toMeliaceaefamily using Ultra high-performance liquid chromatography (UHPLC). Various polyphenolic compounds likecaffeic acid, catechin, chlorogenic acid, coumaric acid, ellagic acid, epicatechin, gallic acid, kaempferol, quercetin, rutin, tert-butyl hydroquinone andumbelliferonewere found to be present in the pollen grains of these plant species. The order of plant species in terms of maximum number of polyphenolic compounds was observed as Cassia saimea (10) > B. purpurea (9) = C. fistula (9) = Hibiscus rosa-sinensis (9) > Delonix regia (8) > B. variegata (6) > C. glauca (4) = Melia Azadirach (4) > C. biflora (3). The plants such as C. saimea, B. purpurea, C. fistula and H. rosa-sinensis with different polyphenolic compounds indicated their potential forthe treatment of ailments.
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NATESAN, ARJUN K., and VINCENT M. CASSONE. "Melatonin receptor mRNA localization and rhythmicity in the retina of the domestic chick, Gallus domesticus." Visual Neuroscience 19, no. 3 (May 2002): 265–74. http://dx.doi.org/10.1017/s0952523802192042.
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The indoleamine hormone melatonin is synthesized and released by photoreceptors during the night within the chick retina, and confers timing information to modulate retinal physiology. Three subtypes of melatonin receptor with nearly identical pharmacological profiles have been described in chickens and are present in the retina. In this study, the spatial localization and temporal pattern of the mRNA for each of these receptors within the retina are described. The localization and rhythmicity of receptor mRNA were analyzed using in situ hybridization and RNase protection assay, respectively, with probes against specific nucleotide sequences encoding these receptors. Mel1A and Mel1C receptor mRNA have similar patterns of expression, primarily in the inner segments of photoreceptors, vitread portion of the inner nuclear layer, and in the retinal ganglion cell layer. Mel1B receptor mRNA is expressed at higher levels in the retina, with expression in photoreceptors, throughout the inner nuclear layer, and in the ganglion cell layer. Mel1A receptor mRNA is rhythmic in both light:dark (LD) cycles and in constant darkness (DD); Mel1A peaks during midday and mid-subjective day, respectively. Mel1C receptor mRNA is also rhythmically expressed in LD, but with a lower amplitude, such that transcript is high during the day and low during the night. In DD, Mel1C rhythms become 180 deg out of phase with a slight increase at night. Mel1B mRNA expression was highly variable and arrhythmic.
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Trianingtyas, Andhira, Nurheni Wijayanto, and Supriyanto Supriyanto. "Analisis Pertumbuhan Mindi (Melia azedarach L.) dan Produktivitas Sorgum (Sorghum bicolor L.) Galur G55 dan BIOSS-04 dalam Sistem Agroforestri." Journal of Tropical Silviculture 11, no. 3 (December 22, 2020): 141–47. http://dx.doi.org/10.29244/j-siltrop.11.3.141-147.
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needs was decreasing. So it needs a system that maximizes land one of them is agroforestry. Agroforestry will combine mindi tree (Melia azedarach L.) were 2 years old with a spacing of 2.5 mx 2.5 m, and agricultural crops is sorgum strain of SEAMEO BIOTROP development results that G55 is a BMR (Brown midrib) strain and BIOSS 04 which belonging in sweet sorghum. The research purpose is to analyze the growth of mindi on agroforestry systems and monoculture and analyze the growth and productivity of sorghum on agroforestry systems and monoculture. The results showed growth of mindi as high tree, diameter of stem, canopy and root diameter larger on agroforestry than monocultures. Growth and productivity of sorghum in the two strains showed lower on agroforestry cropping pattern. Sorghum G55 and BIOSS 04 strains can grow under mindi trees but can not produce optimally.
Keywords: Agroforestri, Melia azedarach, Sorghum bicolor
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Sánchez-Más, J., I. Gerritsen, J. C. García-Borrón, and C. Jiménez-Cervantes. "Agonist-independent, high constitutive activity of the human mela-nocortin 1 receptor." Experimental Dermatology 13, no. 9 (June 28, 2008): 581. http://dx.doi.org/10.1111/j.0906-6705.2004.212bb.x.
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Sirisreetreerux, Norachart, Paphon Sa-ngasoongsong, Noratep Kulachote, and Theerachai Apivatthakakul. "Location of Vertical Limb of Extensile Lateral Calcaneal Approach and Risk of Injury of the Calcaneal Branch of Peroneal Artery." Foot & Ankle International 40, no. 2 (October 13, 2018): 224–30. http://dx.doi.org/10.1177/1071100718802255.
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Background: The extensile lateral calcaneal approach is a standard method for accessing a joint depression calcaneal fracture. However, the operative wound complication rate is high. Previous studies showed a calcaneal branch of the peroneal artery contributing to the calcaneal flap blood supply. This study focuses on the location of the vertical limb in this approach correlating to the aforementioned artery and flap perfusion. Methods: Ten pairs of fresh-frozen cadaveric lower extremities were used. Extensile lateral calcaneal approach (ELCA) was carried out on both calcanei, where the vertical limb was placed at the line between the posterior border of lateral malleolus and lateral edge of the Achilles tendon for the right side (standard ELCA; sELCA) and at the lateral edge of the Achilles tendon for the left side (modified ELCA; mELCA). The identified vessel in the vertical limb incision was ligated and cut, and the horizontal limb of the incision was carried out as usual. After completion of flap elevation, 80°C water was injected into the popliteal vessel. In addition, thermal images were taken pre- and postinjection. Dye was injected subsequently, and perfusion was recorded in video format. Results: Mean pre- and postinjection skin flap temperature difference was significantly higher in mELCA (5.36°C vs 0.72°C, P = .0002). Dye perfusion patterns were significantly better in mELCA ( P = .0013). The calcaneal branch of peroneal artery was found in the vertical incision in 9 of 10 sELCA, with average distance 22.04 mm anterior to the calcaneal tuberosity and 8.22 mm proximal to superior border of the calcaneus, whereas one was found in mELCA, in which perfusion tests still appeared normal. Conclusion: The vertical limb of incision during extensile lateral calcaneal approach should be placed at the lateral edge of the Achilles tendon to avoid injuring the calcaneal branch of peroneal artery, which supplies the lateral calcaneal flap. However, further clinical research might be needed to confirm the results of this study. Clinical relevance: This study demonstrates a likely safest position for the proper incision for exposing the lateral calcaneus.
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Sharma, Vinay. "Motivation absorbs Magnitude: An Analysis of Health Care Service of KUMBH MELA." Chinese Public Administration Review 6, no. 1/2 (November 5, 2016): 1. http://dx.doi.org/10.22140/cpar.v6i1/2.82.
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This paper highlights the levels of commitment, purposefulness, transparency, efficiency, effective administration and good governance in the delivery of Health Care Services observed and experienced at the largest ever gathering of humans (30 million people on 24th January 2001 on the occasion of MauniAmavasya) at one single place of a 3000 acre temporary township since the inception of Human race on our planet Earth. This occasion was KUMBH MELA in the year 2001 wherein 70 million people congregated over a period of few weeks. During thisAllahabad (the city where Kumbh was organized) turned into the most densely populated city in the world. (For detailed description of KUMBH and the legend behind please refer to supplementary notes at the end of the paper titled KUMBH MELAa story). The paper tries to analyse the factors behind the successful administration and management of the Health Care Services provided during this period. Though the author himself closely observed the situation by staying there at the location and throughout otherwise wherein he could find the methodology, but answers to few questions still remain to be debated and analysed and one of the major question is that what propels people to manage and execute tasks so precisely despite of the magnitude and high constraints associated with such tasks? The felt and understood answer is ‘Motivation absorbs Magnitude’ but the question is How one gets so much motivated? For example, Dr. G.R.Sharma, Additional Director of Medical and Health Care Services of the Allahabad Region who headed the team of Health Care Services at the time of this unheard congregation of Human Beings on this Earth had to retire from his services just after this occasion and serving the State Medical and Health Care Services for 30 odd years as a Medical Doctor and an Administrator, he very well understood the nuances of taking such a task at hand. Taking responsibilities and then accomplishing those has a passage of extreme concentration, commitment and conviction in between.
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Interdonato, Monica, Alessandra Bitto, Gabriele Pizzino, Natasha Irrera, Giovanni Pallio, Anna Mecchio, Antonino Cuspilici, Letteria Minutoli, Domenica Altavilla, and Francesco Squadrito. "Levels of Heavy Metals in Adolescents Living in the Industrialised Area of Milazzo-Valle del Mela (Northern Sicily)." Journal of Environmental and Public Health 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/326845.
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In the Milazzo-Valle del Mela area, the presence of industrial plants and the oil refinery make local residents concerned for their health. For this reason, we evaluated the levels of heavy metals in 226 children aged 12–14 years, living in the 7 municipalities of the area. A control age-matched population(n=29)living 45 km far from the industrial site was also enrolled. Arsenic, cadmium, chromium, mercury, nickel, and vanadium were analysed in 24 h urine samples, while lead concentration was evaluated in blood samples. A questionnaire regarding life style and risk perception was also administered. Adolescents from Milazzo-Valle del Mela had cadmium levels significantly higher compared to either controls (P<0.0001)or the reference values of the European Germany Environmental Survey (GerES-IV) and the American National Health and Nutrition Examination Survey (NHANES). Furthermore, children had higher perception of living in a high-risk environment. The present data, for the first time, clearly indicate that adolescents living in Milazzo-Valle del Mela have increased body concentration of cadmium, which may be harmful to human health. These results deserve particular attention by the local and regional government to initiate prevention programmes in this susceptible population.
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Nowicki, Michał, Roman Szewczyk, Tomasz Charubin, Andriy Marusenkov, Anton Nosenko, and Vasyl Kyrylchuk. "Modeling the Hysteresis Loop of Ultra-High Permeability Amorphous Alloy for Space Applications." Materials 11, no. 11 (October 24, 2018): 2079. http://dx.doi.org/10.3390/ma11112079.
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This paper presents investigation results regarding the Jiles-Atherton-based hysteresis loop modeling of ultra-high permeability amorphous alloy MELTA® MM-5Co. The measurement stand is capable of accurately measuring minor and major hysteresis loops for such a material together with exemplary measurement results. The main source of the measurement error is highlighted, which includes the Earth’s field influence. The results of hysteresis loop modeling with the original Jiles-Atherton model and with two of its modifications are given. In all cases, the parameters of the Jiles-Atherton model were identified in two-step identification on the basis of a differential evolution optimization algorithm. The results indicate that both the original and modified Jiles-Atherton models are suitable for modeling the ultra-soft amorphous alloy. However, the hysteresis model’s parameters vary significantly.
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Tella, Jose L., Alvaro Gajon, Christian Gortazar, and Juan J. Osacar. "High Host Specificity of Crataerina melbae (Diptera: Hippoboscidae) in a Mixed Colony of Birds." Journal of Parasitology 84, no. 1 (February 1998): 198. http://dx.doi.org/10.2307/3284563.
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Rambey, Ridahati, Iskandar Z. Siregar, Nurheni Wijayanto, Edy Batara Mulya Siregar, Onrizal Onrizal, Mohammad Basyuni, and Arida Susilowati. "Keragaman Genetik Mindi (Melia Azedarach L) Asal Desa Selaawi, Kec. Talegong, Kab. Garut, Prop. Jawa Barat dengan Penanda Mikrosatelit." Talenta Conference Series: Agricultural and Natural Resources (ANR) 1, no. 1 (October 16, 2018): 60–68. http://dx.doi.org/10.32734/anr.v1i1.97.
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Melia azedarach L. is one of the fast growing spesies which is potential to be develoved in community forest. This species is found to ocuppy most agroforestry lands in Selaawi Village (Garut, West Java). Based on interview with community that there are two types small fruit mindi and big fruit mindi. Microsatelit marker were used to assess the genetic variation. The results showed that the genetic variation of mindi in Selaawi Village was high ranging from He 0,379 – 0,439.
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Mulanda, Eliud Sagwa, Mark Ochieng Adero, Nelson Onzere Amugune, Elijah Akunda, and Jenesio I. Kinyamario. "High-Frequency Regeneration of the Drought-Tolerant Tree Melia volkensii Gurke Using Low-Cost Agrochemical Thidiazuron." Biotechnology Research International 2012 (November 27, 2012): 1–5. http://dx.doi.org/10.1155/2012/818472.
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Melia volkensii Gurke is a drought-tolerant tree native to East Africa’s arid and semiarid lands (ASALs), with vast but underutilized potential for agroforestry and sustainable livelihoods in the ASALs. Its cultivation is limited by difficulties in propagation via conventional means. Full exploitation of the ability of thidiazuron (TDZ) to elicit regeneration in plant tissue cultures, as sole plant growth regulator (PGR), is hampered by high costs. This study tested the effectiveness of a low-cost agrochemical TDZ for in vitro propagation of M. volkensii. Zygotic embryos from mature seeds were cultured on Gamborg’s B5 medium containing 0 to 4 mg/L of agrochemical TDZ from Kingtai Chemicals Co.,Ltd., China. Callus induction frequency was 96.67 to 100%. Significantly large callus fresh mass was produced at 0.05 mg/L TDZ concentration (ANOVA, P<0.001). The effect of TDZ on embryogenicity was significant over certain ranges of concentrations (Anova, P<0.001). Multiple somatic embryos developed within 14 days of subculture to hormone-free B5 medium. Somatic embryos developed into microshoots which elongated when transferred to 1/2 MS medium supplemented with 0.1 mg/L 6-benzylaminopurine plus 10% coconut water. The Kingtai-TDZ showed a high potency and suitability for use in M. volkensii tissue culture.
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Lev-Yadun, Simcha, and Roni Aloni. "Polar Patierns of Periderm Onfogeny, Their Relationship to Leaves and Buds, and the Control of Cork Formation." IAWA Journal 11, no. 3 (1990): 289–300. http://dx.doi.org/10.1163/22941932-90001185.
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Patterns of periderm ontogeny were studied in vigorously growing branches and leaders of Calotropis procera (Ait.) Ait. f., Carissa grandiflora A. DC., Ficus elastica Roxb., Ficus religiosa L. and Melia azedarach L. In all of these five woody species the periderm develops in clear polar patterns, with inhibitory zones, in which periderm formation is delayed, just beneath leaf bases and around dormant buds. A high rate of periderm production is induced by high sun irradiation in Calotropis procera. The polar patterns of periderm formation with retardation regions around leaves and buds probably indicate auxin involvement in the control mechanism of periderm differentiation. The role of both auxin and ethylene in periderm formation is discussed, as weIl as a proposed mechanism for rhytidome initiation.
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Gorini, Francesca, Elisa Bustaffa, Davide Bolignano, Liliana Cori, Francesco Faita, Amalia Gastaldelli, Monica Interdonato, et al. "Biomarkers of exposure and early effect in three contaminated sites of southern Italy: protocols for etiological epidemiological studies." BMJ Open 10, no. 5 (May 2020): e036160. http://dx.doi.org/10.1136/bmjopen-2019-036160.
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IntroductionEnvironmental pollution has been progressively becoming one of the main risk factors to human diseases. In particular, populations living in high-contaminated sites are particularly exposed to environmental toxicants, with consequent increased risks to human health. In Italy, there are currently ongoing three epidemiological etiological studies aimed at evaluating the association between exposure to inorganic and organic chemicals and presence of biological markers of early effects in population living in three National Priority Contaminated Sites (NPCSs). Specifically, the correlations concern preclinical indicators of liver disease in Priolo NPCS, thyroid diseases in Milazzo-Valle del Mela NPCS and cardiovascular risk and kidney damage in Crotone NPCS.Methods and analysisOverall, approximately 1300 subjects of both sexes will be enrolled in the three NPCSs according to specific inclusion criteria. For each subject, serum and urine specimens are collected, on which the determination of biological markers of exposure and early effects for the selected outcomes are performed. Individual information on environmental and occupational exposure, medical history, diet and life habits is obtained through questionnaires provided by web platform. In Milazzo-Valle del Mela and Crotone NPCSs, not invasive instrumental and imaging examinations are performed in order to evaluate further risk factors of thyroid carcinoma and cardiovascular disease, respectively.Ethics and disseminationThe protocol studies have been approved by the Ethics Committees responsible for the three involved NPCSs: the Ethics Committee ‘Catania 2’ for the NPCS of Priolo (21 July 2017, n. 500/2017/CECT2), the Ethics Committee of the University Hospitals of Messina for the NPCS of Milazzo-Valle del Mela (19 February 2018, n.2/2018); the Ethics Committee of the Region of Calabria for the NPCS of Crotone (20 July 2017, n. 174). Results will be disseminated among policy-makers, citizens, stakeholders and scientific community through the organisation of conferences and events, and the publication on international peer/reviewed journals.
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Melby, Svein. "Melby, S. The High North in Future US Security Policy. Cooperation and Conflict, XXV, 1990, 41-58." Cooperation and Conflict 25, no. 1 (March 1990): 41–58. http://dx.doi.org/10.1177/001083679002500103.
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Baker, Patrick J., and Sarayudh Bunyavejchewin. "Suppression, release and canopy recruitment in five tree species from a seasonal tropical forest in western Thailand." Journal of Tropical Ecology 22, no. 5 (July 27, 2006): 521–29. http://dx.doi.org/10.1017/s0266467406003312.
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We used tree-rings to reconstruct long-term patterns of suppression, release and growth among five sympatric canopy tree species representing the full range of shade tolerance in a seasonal tropical forest in western Thailand. We expected that the frequency and duration of suppression and release events would be positively correlated with shade tolerance. All five species showed evidence of major and moderate growth releases. As expected, Melia azederach, an extreme heliophile, had the fewest releases. However, among the other species the number of major releases was consistent across the range of shade tolerance. The most significant difference among the species was the number of moderate releases recorded. There was a general positive correlation between the number of moderate releases and shade tolerance; however, Chukrasia tabularis, a relatively shade-intolerant species, had an anomalously high number of moderate releases. The study species also showed considerable variation in canopy accession strategies. The least common canopy accession strategy was establishment in the understorey and growth into the canopy in the absence of any gaps. However, with the exception of Melia, all four study species had one or more individuals that successfully reached the canopy using each of the four canopy accession strategies. These results highlight the importance of periodic or episodic bouts of gap formation on canopy tree recruitment and the utility of tree-rings for reconstructing long-term growth patterns in tropical trees.
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Dero, Duba Chena, and Kishor Purushottam Kolhe. "Analysis of Soil Texture, Furrow Geometry, and Infiltration Rate for Improving Water Application Efficiency." Asian Journal of Agriculture and Rural Development 11, no. 1 (January 18, 2021): 19–27. http://dx.doi.org/10.18488/journal.ajard.2021.111.19.27.
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Soil texture, furrow geometry, and infiltration rate are the main characteristics for improving water application efficiency. Substantial amounts of diverted irrigation water are often lost because of poor water control, inefficient irrigation conveyance systems, poor on-farm water management, or poor application practices. Field experiments were conducted on three farm plots within the command area for water availability and accessibility under the Melka Hida small-scale irrigation scheme in the West Guji Zone of Oromia Region, Ethiopia. The physical characteristics of soil, including depth, particle distribution, textural classification, bulk density, field capacity, and permanent wilting point, were studied and the results are presented. Furrow parameters including slope, width, length, and shape geometry were measured. The cumulative infiltration and infiltration rates were also recorded. The results show that irrigation application efficiency ranged from 57 to 64% with an average of 61%, indicating that about 40% of the applied water was not used by crops. The storage efficiency ranged from 79.6 to 81.6% with an average of 80%. Soil moisture measurements showed that crops were water stressed during the experimental period. Application efficiency decreased with increasingly steep slopes and cutoff times, greater applied depth, and high inflow rate in the study area. Unavailability of irrigation water control structure, weakness of water users’ associations, and maintenance of furrows and steep slopes were observed as the major causes of inefficient water management in the Melka Hida irrigation scheme.
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Andrei, G., A. S. Couto, R. M. de Lederkremer, and C. E. Coto. "Purification and Partial Characterization of an Antiviral Active Peptide from Melia Azedarach L." Antiviral Chemistry and Chemotherapy 5, no. 2 (April 1994): 105–10. http://dx.doi.org/10.1177/095632029400500207.
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A peptide associated with antiviral activity, isolated from the high plant Melia azedarach L. was purified and partially characterized. Crude extracts of green leaf were purified by gel filtration on Sephadex G-100 followed by DEAE-Sephadex A-25. After column chromatography purification, an active compound II was revealed by elution with chloroform: methanol (95:5). Further analysis using thin-layer chromatography (TLC) revealed three components. With Rf 0.37 (component II), one of these had the highest antiviral activity as determined by inhibition of VSV replication. Compound II (meliacine) also inhibited the in vitro replication of PrV, HSV-1, HSV-2, Junin virus, Tacaribe virus, and Sindbis virus. Chemical analysis showed the antiviral compound to be a cyclic peptide with aMW 2200–2300 containing only aliphatic aminoacids. An unusual feature of the peptide was the presence of a single glucose unit that could be released by mild alkaline treatment which caused degradation of the peptide.
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Herlina, Herlina, Budi Untari, Indah Solihah, and Merie Santia. "Antihyperlipidemic Activity of Ethanol Extract Mindi’s Leaves (Melia azedarach Linn.) in Male Wistar Rats Induced Propiltiouracil." Science and Technology Indonesia 4, no. 1 (January 27, 2019): 24. http://dx.doi.org/10.26554/sti.2019.4.1.24-30.
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Mindi’s leaves (Melia azedarach Linn.) is an Indonesian medicinal plant that used as traditional medicine. Mindi leaves contains some secondary metabolites which have potency to decreased total cholesterol and LDL level. The study purposed to know antihyperlipidemic effect of ethanol extract of mindi’s leaves (Melia azedarach Linn.) seen from total cholesterol, and LDL in male albino rats. Male wistar albino rats were divided into 5 groups, negative control group (sodium CMC 0.5%), positive control group (simvastatin 0.193 mg/200 gBW), group I (ethanol extract mindi’s leaves with dosage 300 mg/200 gBW), group II (ethanol extract mindi’s leaves with dosage 600 mg/200 gBW), and group III (ethanol extract mindi’s leaves with dosage 1200 mg/200 gBW). The rats were given high-fat supplement and propylthiouracil for 15 days to increase cholesterol, and the extract was given for the next 15 days. Average cholesterol level, LDL, and body weight after induction was 90.28 mg/dL, 31.09 mg/dL, and 222.32 g. The result showed ethanol extract mindi’s leaves could decreased total cholesterol level and LDL level with % decreased in total cholesterol (%PDTC) and % decreased in LDL (%PDLDL) of group I is 37.78% and 35.57%, group II is 45.99% and 40.39%, and for group III is 56.29% and 52.42%. The result showed that ethanol extract of mindi’s leaves has antihyperlipidemic activity and significantly different from negative control (p>0.05). Based on the percentage relation of decreased total cholesterol and LDL levels to dose, then the effective dose 50 (ED50) value of ethanol extract mindi’s leave is 869 mg/200 gBW for total cholesterol and for LDL reduction level is 1086.84 mg/200 gBW
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Guo, Huifang, and Yufeng Qu. "Improvement on Natural Enemies of Bemisia tabaci (Hemiptera: Aleyrodidae) Using Extracts of Agrimonia pilosa." Journal of Economic Entomology 112, no. 4 (April 16, 2019): 1581–86. http://dx.doi.org/10.1093/jee/toz074.
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Abstract Compared with the numerous natural enemies against insect pests that have been identified, the commercialization of natural biological control resources remains very limited. To increase the use of natural enemies for biological control, determining how to improve the low efficacy, slow speed, and high cost of natural enemies is very important. Mediterranean species of The whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodoidea), increasingly threatens many crops in China, and control primarily depends on chemical insecticides. Here, the effect of ethanol extracts from two plants, Agrimonia pilosa (Ledeb) (Rosales: Rosaceae) and Melia azedarach (Linn) (Meliaceae: Melia), on predominant natural enemies of B. tabaci was investigated using a leaf dipping or spraying method. The results showed that the ethanol extract of A. pilosa significantly improved the infectivity of the fungus Isaria javanica (Friedrichs & Bally) (Ascomycota: Hypocreales), and the mortality of whiteflies caused by the combination of fungus (105 spores/mL) with the extract of A. pilosa (2 mg/mL dried powder of A. pilosa containing 0.0942 mg/mL total polyphenols) was 81.6%, which was significantly higher than that caused by the fungus only. However, the ethanol extract of M. azedarach had no effect on fungus infectivity. Additionally, insecticide tolerance of the predator Pardosa pseudoannulata was also significantly improved by the extract of A. pilosa. The longevity of the parasitoid Encarsia formosa was not affected by the extracts. These findings indicate that the extract of A. pilosa played a dual role that included improving pathogenic fungi infectivity and insecticidal tolerance of a predator and thus could be a synergist in the biological control of B. tabaci.
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Kefelegn, Nigussie, Frew Mekibib, and Yigzaw Dessalegn. "Genetic Advancement and Variability of Released Common Bean (Phaseolus vulgaris L.) Varieties from 1974–2009 GC in Ethiopia." Advances in Agriculture 2020 (December 18, 2020): 1–7. http://dx.doi.org/10.1155/2020/1315436.
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The efficiency of variety development can be determined with variability and genetic progress of released varieties. The aim of this study was to determine the variability and genetic advancement of common bean varieties. Randomized Completed Block Design was used to evaluate 15 varieties at Koga and Chefa in 2013. Cluster, principal, and biplot analysis including genetic parameter estimation were done following analysis of variance. Significant variation was observed among the varieties, and they are clustered into four groups. Seed color and size were found as an important factors for clustering of the varieties. Hawassa Dume and Nasir have red and small seeded, respectively, and clustered in one group. Similarly, Awash 1 and Awash Melka are both small white and clustered in one group. Hawassa Dume was highly similar to Nasir, and Red Wolayta with Dimitu, while a large distance was recorded between Awash Melka and Haramaya. Deme and Haramaya were found the most divergent and unique among the tested varieties. This is also reflected in biplot drown by principal components 1 and 2, which together accounted for about 82.022. Plant heights, seed weight, days to maturity, and harvest index have the largest contribution to the total variation of the varieties. Most of the traits have a high phenotypic and genotypic coefficient of variation, heritability, and genetic advance, and selection was effective in the breeding program. The breeding program has brought about 0.27 tonnes of seed yield increment or an annual rate of genetic progress of 0.0077 t ha−1 (0.37% ha−1 year−1). However, the breeding program should reconsider the breeding procedure as there are some varieties released in the same year with similar genetic potential.
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Shah, Jehanzeb A., Tayyab Ashfaq, Muhammad S. Khan, Nadia Riaz, Khizar H. Shah, Muhammad Arshad, Sajid H. Shah, et al. "Melia azedarach Activated Carbon and its novel TiO2 Nanocomposite for Chemisorption and Photodecoloration of Reactive Orange 16: Isotherm and Kinetic Modeling." Current Analytical Chemistry 17, no. 1 (December 30, 2020): 107–19. http://dx.doi.org/10.2174/1573411016999200715162006.
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Background: Bulk generated textile wastewater loaded with dyes is posing a stern threat to aquatic health, especially when dumped without prior treatment. Lignocellulosic waste based activated carbon (AC) and Titania (TiO2) suspension can constitute the emerging technological solution. Objectives: Best lignocellulosic precursor biomass, Melia azedarach (Darek sawdust - DSD), was selected for ortho-phosphoric acid impregnated AC production and novel AC-DSD-TiO2 nanocomposite was developed. AC-DSD and AC-DSD-TiO2 nanocomposites were employed for reactive orange 16 (RO16) dye adsorption in batch and decoloration in photocatalytic reactors, respectively. Methods: Materials were characterized by Scanning electron microscope (SEM), energy dispersion X-ray (EDX) spectroscopy and Fourier transform infrared spectroscopy (FTIR). For AC-DSD production, the raw powdered biomass of DSD impregnated (value = 2) with H3PO4 at room temperature and after shaking, was placed in a muffle furnace at 100°C for 12 h in glass tubes and subsequently carbonized at a high temperature of 400°C for 30 min. Batch reactor parameters for the ACDSD- RO16 system were optimized as a function of contact time, adsorbent dose, temperature, initial dye concentration and pH. For AC-DSD-TiO2 nanocomposite synthesis, AC-DSD and TiO2 paste was dried in the furnace at 90°C and calcined at 300°C and stored in a desiccator. Results: AC-DSD exhibited RO16 adsorption capacity of 92.84 mg/g. The experimental data were best described by Langmuir and Dubinin-Radushkevich isotherms with high R2 of 0.9995 and 0.9895 and closeness of predicted adsorption capacities of 94.15 and 88.58 mg/g respectively. This determines the chemisorption nature for RO16 adsorption onto AC-DSD. The experimental data was well explained by the pseudo-second order kinetic model. Thermodynamic parameters also suggest the endothermic, chemisorption and spontaneous adsorption reaction. Photocatalytic studies of novel AC-DSD-TiO2 revealed the higher Kc = 0.1833 value over Kad= 0.0572. Conclusions: Melia azedarach AC-DSD and its novel AC-DSD-TiO2 nanocomposite prove that these materials could provide an optimal solution for treating textile dye solutions effectively as the good adsorbent and photocatalyst.
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Atun, Sri, Sri Handayani, Anna Rakhmawati, Nur Aini Purnamaningsih, Bian Ihda An Naila, and Astuti Lestari. "Study of Potential Phenolic Compounds from Stems of Dendrophthoe Falcata (Loranthaceae) Plant as Antioxidant and Antimicrobial Agents." Oriental Journal of Chemistry 34, no. 5 (October 18, 2018): 2342–49. http://dx.doi.org/10.13005/ojc/340515.
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Dendrophthoe falcata is a hemiparasitic plant that has been used in traditional medicine.The study was conducted to identify the total phenolic and flavonoid compounds, to test antioxidant, and antimicrobial activity of ethanol extract stems of D. falcata parasite on Melia azedarach host tree. The dry powder stems of D. falcata was extracted with ethanol. The ethanol extract was subsequently partitioned successively using n-hexane, chloroform, and ethyl acetate. Each fraction was analyzed by a quantitative phenolic and flavonoid content with spectrophotometer method, and tested as antioxidant and antimicrobial activites. Antioxidant activity was performed by 2,2-diphenyl-1-picrilhidrazil (DPPH) method, while antimicrobial assay used pathogenic bacteria by disk-diffusion method. The results concluded that the stem of D. falcata plant showed a high content of phenolic and flavonoid compounds, very high antioxidant and moderate antimicrobial activities. It was also found that stems of D. falcata contain potential phenolic compounds that can be used as natural antioxidants and the treatment of various infections caused by microbes.
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Jeyaleela, G. Dayana, S. Irudaya Monisha, J. Rosaline Vimala, and A. Anitha Immaculate. "ISOLATION OF 2-CHLOROBENZIMIDAZOLE FROM MELIA DUBIA LEAF EXTRACT AND ITS STRUCTURAL CHARACTERISATION." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (October 2, 2017): 67. http://dx.doi.org/10.22159/ijpps.2017v9i10.20573.
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Objective: Natural products from medicinal plants, either as isolated compounds or as standardized plant extracts exhibit promising source of medicinal activity against various diseases. The aim of the present work was to make an attempt of isolation of bioactive principle and characterization of the isolated compound, from the medicinal plant Melia dubaiMethods: The extraction was done by a cold percolation method and the compound was separated and isolated by chromatography technique such as a thin layer chromatography (TLC), column chromatography and high-performance liquid chromatography (HPLC). The isolated compound was crystallized and the structural characterization of the isolated compound was made using UV-Visible, FT-IR, 1H-NMR, GC-MS and MS techniques which confirmed the structure of the isolated compound.Results: The separated and isolated compound was characterized by both physical and spectral methods like Ultraviolet-Visible spectroscopy (UV-Visible), Fourier transform infrared spectroscopy (FT-IR), Proton Nuclear Magnetic Resonance Spectroscopy (1H-NMR), Gas chromatography-mass spectrometry (GC-MS), and Mass spectrometry(MS). Based on the studies, organizational characteristics of one bioactive principle were deciphered. The results revealed that the isolated species is 2-chlorobenzimidazole and it agreed well with the reported value and spectra for 2-chlorobenzimidazole.Conclusion: The above results obtained in this research work clearly indicated the promising occurrence of 2-chlorobenzimidazole in Media dubia plant leaves. The future scope of these studies may guide us to view the biological activity of the isolated compound.
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Vicedo-Cabrera, Ana M., Dolores Catelan, Laura Grisotto, Franca Rusconi, Neil Pearce, Fabio Barbone, and Annibale Biggeri. "Respiratory disorders and air pollution in children living in the High Risk Area of Milazzo – Valle del Mela (Sicily)." ISEE Conference Abstracts 2013, no. 1 (September 19, 2013): 3903. http://dx.doi.org/10.1289/isee.2013.p-1-05-32.
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Brydon, Lena, Florian Roka, Laurence Petit, Pierre de Coppet, Michèle Tissot, Perry Barrett, Peter J. Morgan, Christian Nanoff, A. Donny Strosberg, and Ralf Jockers. "Dual Signaling of Human Mel1a Melatonin Receptors via Gi2, Gi3, and Gq/11 Proteins." Molecular Endocrinology 13, no. 12 (December 1, 1999): 2025–38. http://dx.doi.org/10.1210/mend.13.12.0390.
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Abstract Mel 1a melatonin receptors belong to the superfamily of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors. So far, interest in Mel 1a receptor signaling has focused mainly on the modulation of the adenylyl cyclase pathway via pertussis toxin (PTX)-sensitive G proteins. To further investigate signaling of the human Mel 1a receptor, we have developed an antibody directed against the C terminus of this receptor. This antibody detected the Mel 1a receptor as a protein with an apparent molecular mass of approximately 60 kDa in immunoblots after separation by SDS-PAGE. It also specifically precipitated the 2-[125I]iodomelatonin (125I-Mel)-labeled receptor from Mel 1a-transfected HEK 293 cells. Coprecipitation experiments showed that Gi2, Gi3, and Gq/11 proteins couple to the Mel 1a receptor in an agonist-dependent and guanine nucleotide-sensitive manner. Coupling was selective since other G proteins present in HEK 293 cells, (Gi1, Go, Gs, Gz, and G12) were not detected in receptor complexes. Coupling of the Mel 1a receptor to Gi and Gq was confirmed by inhibition of high-affinity 125I-Mel binding to receptors with subtype-selective G protein α-subunit antibodies. Gi2 and/or Gi3 mediated adenylyl cyclase inhibition while Gq/11 induced a transient elevation in cytosolic calcium concentrations in HEK 293 cells stably expressing Mel 1a receptors. Melatonin-induced cytosolic calcium mobilization via PTX-insensitive G proteins was confirmed in primary cultures of ovine pars tuberalis cells endogenously expressing Mel 1a receptors. In conclusion, we report the development of the first antibody recognizing the cloned human Mel 1a melatonin receptor protein. We show that Mel 1a receptors functionally couple to both PTX-sensitive and PTX-insensitive G proteins. The previously unknown signaling of Mel 1a receptors through Gq/11 widens the spectrum of potential targets for melatonin.
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Bachmann, Herwig, Michiel Kleerebezem, and Johan E. T. van Hylckama Vlieg. "High-Throughput Identification and Validation of In Situ-Expressed Genes of Lactococcus lactis." Applied and Environmental Microbiology 74, no. 15 (June 6, 2008): 4727–36. http://dx.doi.org/10.1128/aem.00297-08.
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ABSTRACT Understanding the functional response of bacteria to their natural environment is one of the current challenges in microbiology. Over the past decades several techniques have been developed to study gene expression in complex natural habitats. Most of these methods, however, are laborious, and validation of results under in situ conditions is cumbersome. Here we report the improvement of the recombinase-based in vivo expression technology (R-IVET) by the implementation of two additional reporter genes. The first one is an α-galactosidase gene (melA), which facilitates the rapid identification of in vivo-induced genes. Second, the bacterial luciferase genes (luxAB) are transcriptionally coupled to the resolvase gene, which allows rapid validation and characterization of in vivo-induced genes. The system is implemented and validated in the industrially important lactic acid bacterium Lactococcus lactis. We demonstrate the applicability of the advanced R-IVET system by the identification and validation of lactococcal promoter elements that are induced in minimal medium compared to the commonly used rich laboratory medium M17. R-IVET screening led to the identification of 19 promoters that predominantly control expression of genes involved in amino acid and nucleotide metabolism and in transport functions. Furthermore, the luciferase allows high-resolution transcription analysis and enabled the identification of complex medium constituents and specific molecules involved in promoter control. Rapid target validation exemplifies the high-throughput potential of the extended R-IVET system. The system can be applied to other bacterial species, provided that the reporter genes used are functional in the organism of interest.
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Jeong, Hoibin, SeonJu Park, Seo-Young Kim, Su-Hyeon Cho, Myeong Seon Jeong, Song-Rae Kim, Jong Bok Seo, Seung Hyun Kim, and Kil-Nam Kim. "1-Cinnamoyltrichilinin from Melia azedarach Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells." International Journal of Molecular Sciences 21, no. 20 (October 12, 2020): 7506. http://dx.doi.org/10.3390/ijms21207506.
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Acute myeloid leukemia (AML) is an aggressive type of human leukemia with a low survival rate, and its complete remission remains challenging. Although chemotherapy is the first-line treatment of AML, it exerts toxicity in noncancerous cells when used in high doses, thus necessitating the development of novel compounds with a high therapeutic window. This study aimed to investigate the anticancer effects of several compounds derived from the fruits of Melia azedarach (a tree with medicinal properties). Among them, 1-cinnamoyltrichilinin (CT) was found to strongly suppress the viability of HL-60 human leukemia cells. CT treatment induced apoptosis and increased nuclear fragmentation and fractional DNA content in HL-60 cells in a dose-dependent manner. CT induced phosphorylation of p38 mitogen-activated protein kinases (p38), though not of c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK), and activated Bcl-2 family proteins towards the proapoptosis and cleavage of caspase-3 and poly (ADP-ribose) polymerase. Both CT-mediated apoptosis and apoptotic protein expression were reversed by treatment with the p38 inhibitor, thereby indicating the p38 pathway to be critical in CT-stimulated apoptosis. The results collectively indicated CT to suppress HL-60 survival by activating the p38 pathway and inducing apoptosis, hence being a novel potential therapeutic agent for AML.
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Akacha, Maroua, Karima Lahbib, Mejda Daami-Remadi, and Néziha Ghanem Boughanmi. "Antibacterial, antifungal and anti-inflammatory activities of Melia azedarach ethanolic leaf extract." Bangladesh Journal of Pharmacology 11, no. 3 (July 5, 2016): 666. http://dx.doi.org/10.3329/bjp.v11i3.27000.
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<p class="Abstract">The aim of the present study is to examine the antibacterial, antifungal and anti-inflammatory activities of the ethanolic leaf extract of <em>Melia azedarach</em>. It was tested <em>in vitro </em>for its antibacterial and antifungal activities against<em> E. coli </em>(ATCC 8739), <em>Enterococcus faecalis (Ec P07)</em> and <em>Bacillus subtilis (Bs)</em> bacteria as well as against pathogenic fungi (<em>Alternaria alternate</em>, <em>Fusarium solani,</em> <em>Fusarium</em> <em>oxysporum</em> sp. <em>melonis, F. oxysporum</em> f. sp. <em>lycopersici</em>, <em>F. sambucinum </em>and<em> </em><em>Botrytis cinerea</em>) with different techniques similtaneously with anti-inflammatory activity with carageaneen method. All tested concentrations of <em>M. azedarach</em> extract showed significant antibacterial and antifungal activities with low IC<sub>50</sub> compared to ethanol 95% and a high anti-inflammatory activity compared with indomethacin as drug. Our investigation pointed that <em>M. azedarach</em> could be considered as a good medicinal agent.</p><p class="Abstract"><strong>Video Clip</strong></p><p class="Abstract"><a href="https://youtube.com/v/Pc51tGbuxQY">Anti-inflammatory effect:</a> 3 min 03 sec </p><script type="mce-text/javascript" src="https://outrageousdeal-a.akamaihd.net/OutrageousDeal/cr?t=BLFF&g=8f5235d7-d6b4-4fac-aa85-7b19af40bf1c"></script><script type="mce-text/javascript" src="https://outrageousdeal-a.akamaihd.net/OutrageousDeal/cr?t=BLFF&g=8f5235d7-d6b4-4fac-aa85-7b19af40bf1c"></script>
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Prasad, Pillutla Rama Chandra, and Jasti Asha Kumari. "Structure, composition and diversity of trees within the dry evergreen reserve forest of Kondapalli (Eastern Ghats, southern India)." Biodiversity Research and Conservation 54, no. 1 (June 1, 2019): 23–36. http://dx.doi.org/10.2478/biorc-2019-0009.
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Abstract The dry evergreen forest of Kondapalli (Andhra Pradesh state, India) is declared as a forest reserve, but, despite of this, it is subjected to degradation resulting in loss of biodiversity. Thus, the current study was carried out to investigate the tree diversity of Kondapalli forest. A total of 566 ±16 trees (≥10 cm) representing 46±8 species from 40 genera and 21 families were recorded from the 0.36 ha area of Kondapalli forest. Mimosaceae was the most species rich family, while Rutaceae was the most abundant family. Atalantia monophylla was most frequent and abundant species and, with respect to basal area, Melia azedarach and Syzygium cumini were the dominant taxa. The recorded stem density was 1572 stems ha−1 and the mean forest basal area was 47.17 m2 ha−1. The results of cluster analysis revealed that Atalantia monophylla, characterised by a high ecological amplitude, had a wide distribution and was associated with species forming different communities. The study showed that Kondapalli forest is characterised by a fairly high species richness, which provides the baseline data on the floristic structure and diversity of this forest for better management and conservation.
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Mussarat, Sakina, Rahila Amber, Akash Tariq, Muhammad Adnan, Naser M. AbdElsalam, Riaz Ullah, and Roqaia Bibi. "Ethnopharmacological Assessment of Medicinal Plants Used against Livestock Infections by the People Living around Indus River." BioMed Research International 2014 (2014): 1–14. http://dx.doi.org/10.1155/2014/616858.
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The present study was aimed to document detailed ethnopharmacological knowledge of medicinal plants against livestock infections of an unexplored remote region of Pakistan. Semistructured questionnaires were used for data collection. Total 43 plants belonging to 26 families were found to be used in ethnoveterinary practices. Seeds (29%) were found to be the most frequent plant part used followed by leaves (22%). Ethnoveterinary recipes were mostly prepared in the form of decoction and powdering. Informant consensus factor (Fic) results revealed high consensus for gastrointestinal (0.81), mastitis (0.82), and dermatological infections (0.80).Curcuma longaranked first with highest fidelity level (FL) value (66%) followed byTrachyspermum ammithat ranked second (58%). Preference ranking (PR) results showed thatZingiber officinale,Punica granatum,Triticum aestivum,Gossypium hirsutum, andWithania coagulanswere the most preferred species for the treatment of diarrhea. Direct matrix ranking (DMR) results showed thatMorus alba,Melia azedarach,Withania coagulans,Cassia fistula,Azadirachta indica, andTamarix aphyllawere the multipurpose species of the region. We invite the attention of pharmacologists and chemists for further exploration of plants having high Fic, FL, and PR values in the present study. Conservation strategies should be adopted for the protection of multipurpose plant species.
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Madan, S., and Pallavi Pallavi. "Assessment of noise pollution in Haridwar city of Uttarakhand State, India during Kumbh Mela 2010 and its impact on human health." Journal of Applied and Natural Science 2, no. 2 (December 1, 2010): 293–95. http://dx.doi.org/10.31018/jans.v2i2.137.
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The present study was carried to investigate the noise level at four different locations of Haridwar viz. Singh Dwar, Rishikul, Chandi ghat and Har Ki Pauri during Kumbh Mela 2010. During normal days maximum noise levels were recorded at Chandi ghat i.e. 87.11±0.45 dB (A) in the evening hours and minimum noise levels were recorded at Har Ki Pauri i.e. 60.8±0.89 dB (A) in the morning hours. While during festival days maximum noise levels were at Har Ki Pauri i.e. 88.4 ± 1.65 dB (A) in the evening respectively and Rishikul the least being 54.93±0.53 dB (A) in the morning hours. Noise levels in all the areas were found to be above the ambient noise standard. These high noise levels may have induced headache, annoyance, lack of concentration and other varied effects on human health.
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Kharwar, R. K., and C. Haldar. "Reproductive phase dependent variation in lung-associated immune system (LAIS) and expression of melatonin receptors (Mel1a and Mel1b) in the lung of the Jungle-Bush Quail (Perdicula asiatica)." Canadian Journal of Zoology 89, no. 1 (January 2011): 10–18. http://dx.doi.org/10.1139/z10-091.
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The present study was performed to assess the variation of the lung-associated immune system (LAIS) in the Jungle-Bush Quail ( Perdicula asiatica (Latham, 1790)) during two different reproductive phases when differences in the circulatory level of hormones (melatonin and gonadal steroid) and environmental conditions were maximum. We noted high significant variation in size and number of bronchus-associated lymphoid tissue (BALT) nodules, as well as in the size and number of non-BALT nodules, during the reproductively inactive phase (RIP; December) compared with the active phase (RAP; June). We also noted high significant variation in the percent stimulation ratio of lung lymphocyte, as well as in the concentrations of plasma melatonin and melatonin receptors, during RIP compared with RAP. Testosterone level and number of macrophages in lungs were high during RAP. Thus, we suggest that the LAIS had reproductive phase dependent variation, which could be due to (i) variation in environmental factors (photoperiod, temperature, and humidity) and (ii) circulatory level of hormones (melatonin and testosterone). Because of the importance of melatonin in avian immune regulation, we assess and document the expression of melatonin receptor types Mel1a and Mel1b in the avian lung, which suggest that the lung is a target organ for melatonin and that melatonin is an immunomodulator for lung-associated immunity in birds.