Journal articles: 'Medicinal profile'

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Wright, Stephen W. "Career Profile: Medicinal Chemist." Journal of Chemical Education 84, no. 10 (October 2007): 1579. http://dx.doi.org/10.1021/ed084p1579.

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RAKHIMOVA, Sh Kh. "PROTEIN PROFILE OF MEDICINAL PLANTS." Journal of Research in Pharmacy 27_special_issue_7, no. 27_special_issue_7 (2023): 76. http://dx.doi.org/10.29228/jrp.633.

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Zheplinska, Marija, Mikhailo Mushtruk, Volodymyr Vasyliv, Anatolii Kuts, Natalia Slobodyanyuk, Larysa Bal-Prylypko, Mykola Nikolaenko, Olena Kokhan, Yuriy Reznichenko, and Oksana Salavor. "The micronutrient profile of medicinal plant extracts." Potravinarstvo Slovak Journal of Food Sciences 15 (June 28, 2021): 528–35. http://dx.doi.org/10.5219/1553.

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Medicinal plants contain biologically active substances that have a physiological effect on the human body. In the territory of Ukraine, 15 of the most important medicinal plants grow from a medical point of view, among which are Melissa officinalis L and Сalendula officinalis. Micronutrients are necessary for the body in small quantities, not being a source of energy, they take part in their assimilation, as well as in the regulation of various functions and the implementation of the processes of growth and development of the human body. The study aims to establish the micronutrient profile of extracts and infusions from medicinal raw materials – Сalendula officinalis and Melissa officinalis. The established micronutrient profile includes data on the content of such macro- and microelements as calcium, potassium, sodium, iron, zinc, and copper in extracts and infusions from Melissa officinalis L officinalis L and Сalendula officinalis. Sodium predominates from certain macronutrients, the superiority of which is manifested in Сalendula officinalis when infused. A large amount of calcium also passes into the aqueous-alcoholic infusion from Сalendula officinalis. Copper and zinc prevail among the determined microelements in water extracts of Сalendula officinalis. Comparing the results obtained, we can say in the affirmative about the micro- and macro elements that have passed into extracts that Сalendula officinalis is richer in these substances. Because infusions and extracts are recommended to be added as an additional ingredient to vegetable and fruit juices, their positive infusion on the human body will increase the recommended daily requirement of potassium and sodium. Based on the results of this study, extracts and infusions of Melissa officinalis L and Сalendula officinalis can be considered as an essential source of micronutrients for enriching fruit and vegetable juices in canned food for health purposes

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Rawat, Apeksha. "APHANAMIXIS POLYSTACHYA (WALL) PARKER PHARMACOGNOSTIC PROFILE & MEDICINAL USES." Indian Research Journal of Pharmacy and Science 7, no. 1 (March 2020): 2101–2. http://dx.doi.org/10.21276/irjps.2020.7.1.8.

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Sain, Kiran, Beena Yadav, and Rita Goel. "Profile and Training Exposure of Medicinal Plant Growers." IRA-International Journal of Management & Social Sciences (ISSN 2455-2267) 4, no. 2 (September 7, 2016): 432. http://dx.doi.org/10.21013/jmss.v4.n2.p12.

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<div><p><em>An attempt was made to find out the preference of the subsidiary and off-seasonal occupations of horticultural farmers. The study was conducted on 30 medicinal plant growers of Bhiwani , Hisar and Mohindergarh districts of South West Zone of Haryana state. Maximum number of medicinal plant growers were in the age group of 40-56 years (53.3%), hailed from upper caste (60.0%), had nuclear families (86.6%) with slightly more than half of them (56.6%) having family size of 5-7 members, maximum of them had education upto senior secondary level (36.6%) with land holding upto five acres (40.0%). No formal training was attended by any of the growers before starting cultivation of medicinal plants. They had positive attitude towards majority of the aspects related to medicinal plants. </em></p></div>

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Pereira, M. M. A., A. D. Martins, L. C. Morais, J. Dória, V. P. Cavalcanti, F. A. Rodrigues, M. Pasqual, and J. M. Q. Luz. "The Potential of Agro-homeopathy Applied to Medicinal Plants—A Review." Journal of Agricultural Science 11, no. 4 (March 15, 2019): 500. http://dx.doi.org/10.5539/jas.v11n4p500.

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The homeopathic preparations can influence the growth, secondary metabolites production, essential oil yield and phytochemical profile when applied in the grown of medicinal plants. To compile this review articles from existing literature about basic research related to the use of homeopathic preparation on the cultivation of medicinal plants and its influence on the phytochemical profile, growth, yield and composition of essential oil were collected. The bibliographic research was carried out in scientific databases sites—Scopus, Web of Science and PubMed. Seventeen publications were found in which homeopathy was applied in the cultivation of medicinal plants. Its use changed the phytochemical profile, increased the essential oil yield, the production of secondary metabolites (coumarins, alkaloids, phenylpropanoids), the the nutrients absorption and the growth of the medicinal plant species were studied. This review shows that the application of homeopathic preparations in the cultivation of medicinal plants increases the production of secondary metabolites and essential oils that are important for human and animal health therapeutic treatments.The homeopathic preparation application is an alternative for the growth of medicinal plants with ecological balance, and without soil and water contamination. It is also affordable to farmers and researchers. However, further studies are required on its influence on the phytochemical profile of the cultivated medicinal species.

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Mazzari, André Luis D. A., Samantha Frangos, Damaris Silveira, Francisco de Assis Rocha Neves, Flora Milton, Ana Cecília Carvalho, and Jose M. Prieto. "Preclinical pharmacokinetic profile of four traditional medicinal plants." Drug Metabolism and Pharmacokinetics 32, no. 1 (January 2017): S67. http://dx.doi.org/10.1016/j.dmpk.2016.10.270.

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Mazzari, ALDA, S. Frangos, D. Silveira, F. de Assis Rocha Neves, F. Milton, AC Bezerra Carvalho, and JM Prieto. "Preclinical pharmacokinetic profile four native Brazilian medicinal plants." Planta Medica 81, S 01 (December 14, 2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596971.

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Mrabti, Hanae Naceiri, Latifa Doudach, Mouna Mekkaoui, Zineb Khalil, Khouloud Harraqui, Fozia Fozia, Nidal Naceiri Mrabti, et al. "Profile of Medicinal Plants Traditionally Used for the Treatment of Skin Burns." Evidence-Based Complementary and Alternative Medicine 2022 (June 6, 2022): 1–10. http://dx.doi.org/10.1155/2022/3436665.

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Moroccan folk healers use medicinal plants to treat several diseases including skin burns. The traditional knowledge of wound healing is not common among the general population. Only one ethnobotanical survey was carried out in Rabat, Morocco, to track the traditional use of medicinal plants in wound healing. Therefore, our report aimed to study the medicinal plants used in Taza region to treat wound healing. In total, 218 individuals participated in this survey. More than 40 medicinal plants belonging to 30 botanical families were cited as anti-burn remedies. The most commonly used medicinal plants were Agave sisalana L., Nerium oleander L., Tetraclinis articulata Benth., Lawsonia inermis L., Artemisia herba-alba Asso., and Trigonella foenum-graecum L. Most of the used medicinal plants belong to Asteraceae family. Comparing our results with the previous survey, we noted that twelve plants were reported for the first time as wound healing agents. The ethnomedicinal use showed that plants leaves are the most commonly used parts. Pulverization was the selected method of preparation. The direct application of powder to the burns was the most common way of treatment. Our study revealed, for the first time, the importance of medicinal plants to treat skin burns in Taza region. Our results could be considered as the stepping stone for creating a database of wound healing medicinal plants to promote scientific studies on these plants revealing their constituents and side effects.

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Meena, Ajay Kumar, P. Rekha, and T. Satheesh Kumar. "Ethnobotanical, phytochemical and pharmacological profile of Trichosanthes tricuspidata: An updated review." IP International Journal of Comprehensive and Advanced Pharmacology 6, no. 3 (October 15, 2021): 102–7. http://dx.doi.org/10.18231/j.ijcaap.2021.019.

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Herbal medicines, the backbone of traditional medicine in many countries have played an important role in curing the various diseases of humans and animals since ancient time. Medicinal plants are great source of bioactive compounds that have potential beneficial effects in human life. Electronic databases including PubMed, Google Scholar, books and other sources were searched using subject specific key words that were matched by Trichosanthes tricuspidata medicinal plant related useful information on botanical description, plant distribution, ethanobotanical & therapeutic uses, chemical constituents and pharmacological activity etc. Trichosanthes tricuspidata have many medicinal properties like antioxidant, anticancer, antibacterial, antifungal, Larvicidal activity, Anticonvulsant activity, Gastro protective activity and other activities. The Bioactive compounds of Trichosanthes tricuspidata responsible for its various medicinal properties and their effects at the molecular level need to be investigated in more detail. The present review summarizes the Ethnobotanical & therapeutic uses, chemical constituents and pharmacological activity information of Trichosanthes tricuspidata. The pharmacological properties of bioactive compounds in Trichosanthes tricuspidata are required to confirm the ethno medicinal or traditional claims of Trichosanthes tricuspidata for pharmaceutical therapeutic applications.

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Ullah, Asad, Sidra Munir, Yahia Mabkhot, and Syed Badshah. "Bioactivity Profile of the Diterpene Isosteviol and its Derivatives." Molecules 24, no. 4 (February 14, 2019): 678. http://dx.doi.org/10.3390/molecules24040678.

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Steviosides, rebaudiosides and their analogues constitute a major class of naturally occurring biologically active diterpene compounds. The wide spectrum of pharmacological activity of this group of compounds has developed an interest among medicinal chemists to synthesize, purify, and analyze more selective and potent isosteviol derivatives. It has potential biological applications and improves the field of medicinal chemistry by designing novel drugs with the ability to cope against resistance developing diseases. The outstanding advancement in the design and synthesis of isosteviol and its derivative has proved its effectiveness and importance in the field of medicinal chemical research. The present review is an effort to integrate recently developed novel drugs syntheses from isosteviol and potentially active pharmacological importance of the isosteviol derivatives covering the recent advances.

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R. Habib, A. Mohyuddin, Z. Khan, and T. Mahmood. "Analysis of Non-polar Chemical Profile of Melia Azedarach L." Scientific Inquiry and Review 1, no. 1 (November 7, 2017): 49–54. http://dx.doi.org/10.32350/sir/11/010106.

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Medicinal plants are conventionally used for the treatment of various diseases due to their world-wide occurrence and least side effects. Melia azedarach L. belongs to the family Meliaceae, is a highly significant medicinal plant. Extracts of M. azedarach obtained from its different parts such as seed, fruit, flower, leaf, and young branches are reported to exhibit antifungal, antihelmintic, nematicidal, diuretic, cytotoxic, antiproliferative, insecticidal and antioxidant activities. Thus the aim of this study was to explore the chemical profile of non-polar extract of M. azedarach leaves through GC-MS analysis. The identification of phytochemical compounds is based on molecular ion peak, base peak, and fragmentation pattern. GC-MS analysis of hexane extract of M. azedarach showed a highly complex profile, containing ketones, ethers, fatty acid derivatives, methyl esters, 1,3-dipalmitate, 7,8-dihydrocarpesterol, and 2- Undecanol. This study will be useful to explore the active components of medicinal plants and can validate their medicinal value.

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Griz, S. A. S., T. J. Matos-Rocha, A. F. Santos, J. G. Costa, and K. C. Mousinho. "Medicinal plants profile used by the 3rd District population of Maceió-AL." Brazilian Journal of Biology 77, no. 4 (May 4, 2017): 794–802. http://dx.doi.org/10.1590/1519-6984.01116.

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Abstract Herein the use of medicinal plants by the population of the 3rd Sanitary District of Maceió-AL city is reported. Transversal description was conducted from February 2013 to January 2014, with a sample of 116 individuals of both Gender Genders aged over 18 years. The ethnobotanical information interviews ethnobotanical information were obtained through semi - structured questionnaire featuring the use of medicinal plants and social and economical data. Descriptive statistics was applied for quantitative variables as mean and standard deviation and proportions for qualitative variables in the frequency table format. The results showed that 85.34% of the interviewees used plants for medicinal purposes. As the majority of these were (73.28%) females in the age group between 30-60 years of old. Among a total of 45 identified plant species, the highest use frequency were for Boldus Peumus (bilberry), Melissa officinalis (lemon balm), and Mentha piperita (mint). The most widely used plant foliage part was (53.53%) prepared as an infusion (55.5%). The use of medicinal plants in Maceió cityis widespread, highlighting the importance of ethnobotanical knowledge for the study of medicinal plants.

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Bouayyadi, Lahcen, and Lahcen Zidane. "Botanical and medicinal profile of aromatic and medicinal plants: Case of the Gharb region, Morocco." Journal of Pharmacy & Pharmacognosy Research 8, no. 1 (January 1, 2020): 269–79. http://dx.doi.org/10.56499/jppres19.766_8.4.269.

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Context: Medicinal plants remain a source of medical care in developing countries in the absence of an effective medical system. Aims: To establish the list and ethnobotanical characteristics of the most used plants in the Gharb region. Methods: A survey was conducted on more than 704 subjects from the region of which 52.5% were women. The average age of these informants was 41.57 ± 0.51 years and 82.95% were married. Results: The results of this study made it possible to draw up a catalog composed of 187 plant species, divided into 156 genera and grouped into 71 families. Otherwise, 47.44% of respondents confirmed having confidence in traditional medicine. The calculation of the use value showed that the latter varies between 1 and 9 possible uses. However, the Relative Frequency of Citation showed that some species display significant values reaching 9.49% for the species Eucalyptus globules Labill. In addition, the consensual factor of the survey showed a strong association between the most used species like Eucalyptus globules Labill.; Origanum compactum Benth.; Mentha pulegium L; Lavandula dentata L; Chenopodium ambrosioide L.; Marrubium vulgare L., Allium sativum L. and diseases treated by these plants, namely digestive and respiratory diseases. Conclusions: Phytotherapy is undoubtedly the main adopted medicine by the local population of the Gharb region, especially for the treatment of digestive diseases. Myrtaceae, Lamiaceae and Zingiberaceae, represent the most family’s plants mentioned by the respondents.

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Vaishali Patil and Tanvi Dodiya. "Pharmacognostic, Phytochemical and Nutritional Profile of Moringa concanensis Leaves." International Journal of Ayurvedic Medicine 13, no. 1 (April 5, 2022): 55–60. http://dx.doi.org/10.47552/ijam.v13i1.2300.

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The moringa genus has wide varieties cultivated worldwide; out of which only two species are cultivated in india i.e. Moringa oleifera and Moringa concanensis. Moringa oleifera was tested in all the aspects like; standardization parameters of plant and their pharmacological activities. Moringa concanensis Nimmo (Moringaceae) is a traditional medicinal plant, distributed in tropical deciduous forests of India. The standardization parameters play a vital role in quality assessment of plant material. Due to lack of standardization parameters the adulterants are passed as genuine drug. This plant has an impressive medicinal uses along with a good nutritional value. The present investigation provides research regarding standardization parameters as well as phytochemical constituents of M. concanensis. The plant is not edible due to its bitter taste but it has variety of phytochemical constituents as well as it is nutritionally rich. This investigation further helps to develop the formulations having medicinal activity as well as nutritional values.

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Khare, Pragati, Kamal Kishore, and Dinesh Kumar Sharma. "Medicinal uses, Phytochemistry and Pharmacological profile of Madhuca longifolia." Asian Journal of Pharmacy and Pharmacology 4, no. 5 (September 2018): 570–81. http://dx.doi.org/10.31024/ajpp.2018.4.5.5.

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More, Garland Kgosi, Jacques Vervoort, Paul Anton Steenkamp, and Gerhard Prinsloo. "Metabolomic profile of medicinal plants with anti-RVFV activity." Heliyon 8, no. 2 (February 2022): e08936. http://dx.doi.org/10.1016/j.heliyon.2022.e08936.

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Jacques Britto N and Kesavi Durairaj. "Phytochemical profile and medicinal potentials of Lannea Coromandelica stem." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (July 9, 2020): 3465–72. http://dx.doi.org/10.26452/ijrps.v11i3.2490.

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In the history of humanity, great ancestors of Indian sub-continent used plants that possessed unique medicinal properties. They identified the plants from jungles and derived crude drugs out of them for treating infectious diseases. This treatment process was a tradition. In the recent century, this plant-based drug extraction, processing and refining began scientifically by pharmaceutical industries. In this new era, plants with medicinal features are being used in curing broad spectrum of diseases. Lannea Coromandelica (L.C.) is a medicinal plant that belongs to this category. Tribals extensively used it in treating various infectious diseases and common injuries. There have been very few studies on the leaves, barks, flowers, gums and mucilage of this tree. But no preliminary phytochemical composition of L.C. stem has been studied. Therefore, the current work focusses on the screening of the phytochemical profile of the stem of L.C. by the sequential ethanolic extract. Stems of L.C. were procured from Mettur, Tamil Nadu. Thirteen different components were qualitatively analyzed using standard procedures from 100g of L.C. stem extract. In this study, seven components were identified, and their percentage was estimated. Using GC-MS, 50 components were identified of which Pentadecanoic acid, 14-methyl-methyl ester (1.0%) was the major component. The presence of these components in L.C. stem extract can be used in the treatment of different ailments through their antioxidant, anti-arthritic, anti-diabetic, antiinflammatory and antimicrobial activities.

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Hassan, Waseem, Hamsa Noreen, Shakila Rehman, Shehnaz Gul, Syeda Nida Zainab Kazmi, Bakht Zaman, Imdadullah Mohammadzai, Mohammad Yaseen, Ata UR Rahman, and Ali Riaz. "Nutritional and Phytochemical Profile of One Hundred Medicinal Plants." Journal of Nutritional Ecology and Food Research 2, no. 4 (December 1, 2014): 271–87. http://dx.doi.org/10.1166/jnef.2014.1106.

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Elfahmi, Komar Ruslan, Sieb Batterman, Rein Bos, Oliver Kayser, Herman J. Woerdenbag, and Wim J. Quax. "Lignan profile of Piper cubeba, an Indonesian medicinal plant." Biochemical Systematics and Ecology 35, no. 7 (July 2007): 397–402. http://dx.doi.org/10.1016/j.bse.2007.01.003.

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Connor, Kathryn M., Jonathan R. T. Davidson, and L. Erik Churchill. "Adverse-Effect Profile of Kava." CNS Spectrums 6, no. 10 (October 2001): 848–53. http://dx.doi.org/10.1017/s109285290000167x.

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ABSTRACTThe use of alternative therapies has increased substantially over the last decade, particularly for more chronic conditions such as anxiety. Among the most widely used treatments are medicinal herbs, or phytomedicines, such as kava (Piper methysticum), which has demonstrated anxiolytic activity in both animal models and clinical samples. Kava has several advantages over conventional pharmacologic treatments for anxiety—in clinical settings it has been associated with better tolerability and lack of physiologic dependence and withdrawal. However, phytomedicines are not rigorously regulated in the United States and systematically collected safety data are very limited. These issues are a leading concern regarding the safety of medicinal herbs such as kava. In this report, the safety profile for kava is provided, including findings from a study of its use in generalized anxiety disorder. Safety parameters assessed include occurrence of adverse events, withdrawal symptoms, effect on heart rate, blood pressure, laboratory assessments, and sexual function. No differences were found between kava and placebo on any of the parameters evaluated. The data support the safety of kava in treating anxiety at 280 mg kava lactones/day for 4 weeks.

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Mulat, Mulugeta, Fazlurrahman Khan, Gizachew Muluneh, and Archana Pandita. "Phytochemical Profile and Antimicrobial Effects of Different Medicinal Plant: Current Knowledge and Future Perspectives." Current Traditional Medicine 6, no. 1 (January 8, 2020): 24–42. http://dx.doi.org/10.2174/2215083805666190730151118.

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The application of medicinal plants for combating various human ailments, as a food fortificant and additive have been adapted from ancient routine custom. Currently, developing countries use plants as a major source of primary health care. Besides, the emerging drug resistant pathogenic microbes encourage the utilization of medicinal plants as preeminent alternative sources of new bioactive substances. Extensive research findings have been reported in the last three decades. But methods to investigate the phytoconstituent and their biological effects are limited. This review contains brief explanations about the selection of medicinal plants, procedure for obtaining the crude as well as essential oil extracts, phytochemical screening, and in-vitro evaluation of antimicrobial activity. Furthermore, the antimicrobial activity of medicinal plant extracts reported from their respective solvent fractionated and non-fractionated in-vitro analysis has also been described in the present paper. The bioactive substances from medicinal plant along with chemical structure and biological effects are highlighted in the content.

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Ivana Mitrevska, Hristijan Mickoski, Katerina Brezovska, and Aneta Dimitrovska. "Evaluation of in vitro dissolution similarity of bisoprolol film-coated tablets based on Weibull modelling using MATLABTM simulation software." World Journal of Advanced Research and Reviews 10, no. 1 (April 30, 2021): 056–73. http://dx.doi.org/10.30574/wjarr.2021.10.1.0143.

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The aim of this study was to compare the in vitro dissolution behaviour of reference (R) and generic-test (T) medicinal products with non-linear effects model. Mathematical function Weibull, was employed as basis for the non-linear effects model, coupled with MATLABTM simulation software to describe the release profile of the active substance. Medicinal products selected for the presented study include immediate-release tablets Concor 10 mg and Bisoprolol 10 mg, which belongs to BCS class 1 of biopharmaceutics classification system. The result from the study indicated that Weibull distribution function coupled with computer-based program is more useful for comparison of the dissolution profiles. This combined approach provides robust and informative results, with accurate estimation on the in vitro performance for the medicinal products and it’s the most suitable tool for prediction of in vivo behaviour of the medicinal product. In summary, we have employed Simulink graphical programming to design our system in a simulation environment.

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Muchaia, Alexandre Jacinto, and Salvador José António Nanvonamuquitxo. "LEVANTAMENTO ETNOBOTÂNICO DE PLANTAS MEDICINAIS UTILIZADAS PELA COMUNIDADE DE NACUALE, NO PARQUE NACIONAL DAS QUIRIMBAS, MOÇAMBIQUE." Nativa 9, no. 5 (December 28, 2021): 605–11. http://dx.doi.org/10.31413/nativa.v9i5.12260.

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A presente pesquisa teve como objectivo fazer o levantamento Etnobotânico de plantas com poder medicinal utilizadas pela comunidade de Nacuale no Distrito de Ancuabe, Cabo Delgado, Moçambique. Foram realizadas entrevistas com 88 chefes de agregados familiares com propósito de compreender além do perfil socio -económico, as principais plantas usadas para o tratamento de doenças mais frequentes da comunidade desta localidade. As plantas citadas como medicinal foram identificadas e organizadas em função dos valores de concordância de uso principal-CUPc. Por sua vez, foi determinada a diversidade de plantas medicinais usadas na região, bem como as doenças para a qual cada uma das plantas é usada. Cerca de 45% da população que vive na localidade de Nacuale é pobre (rendimento familiar inferior a 15 $/mês). As principais actividades de renda são a agricultura familiar (68%), caça (20%) e pequenos negócios (12%). O difícil acesso aos serviços de saúde convencional faz com que a maioria das populações optem pela medicina tradicional para tratamento de doenças. A Mangifera indica Wall (46,0%), Afizelia quanzensis Welw (37,5%), Moringa oleífera Lam (29,2%) e Carica papaya L (20,8%) foram as espécies mais citadas dentre as utilizadas para o tratamento de doenças. As populações demonstraram ainda ter conhecimento de diversas espécies de plantas medicinais da região (H’=3,04 e J’=0,93), enquanto que as doenças comumente tratadas com recurso destas plantas são a malária (20%), dores de estomago (18 %), dores de cabeça (16%) e reumatismo (13%). Na localidade de Nacuale, o uso da medicina tradicional é ainda uma opção viável pela dificuldade de acesso aos serviços de saúde convencional, agravado pelo baixo nível de escolaridade, pobreza e aspectos socioculturais. As plantas são usadas para tratamento de doenças mais frequentes nessa região. Palavra chaves: etnobotânica; plantas medicinais; Cabo Delgado - Moçambique. Ethnobotanical assessment of medicinal plants used by the community of Nacuale, in the Quirimbas National Park, Mozambique Abstract: The objective of the present research was to conduct an ethnobotanical survey of plants with medicinal uses in the village of Nacuale in Ancuabe District, Cabo Delgado, Mozambique. 88 households were interviewed with the purpose of understanding, in addition to the socio-economic profile, the most common plants used for the treatment of the community's most frequent diseases in this village. The plants cited as medicinal were identified and organized according to the values of concordance of principal use-CUPc. In addition, the diversity of medicinal plants used in the region was determined, as well as the diseases for which each of the plants is used. About 45% of the population living in Nacuale is low-income (household income less than 15 $/month). The main income generating activities are subsistence farming (68%), hunting (20%) and small businesses (12%). The difficult access to conventional health services makes most of the population opt for traditional medicine for the treatment of diseases. Mangifera indica Wall (46.0%), Afizelia quanzensis Welw (37.5%), Moringa oleifera Lam (29.2%), Carica papaya L (20.8%) were cited as the species most used for the treatment of these diseases. The populations also demonstrated knowledge of several species of medicinal plants of the region (H'=3.04 and J'=0.93), and the diseases commonly treated with these plants are malaria (20%), stomach aches (18%), headaches (16%) and rheumatism (13%). Thus, in the village of Nacuale the use of traditional medicine is still a viable option due to the difficulty of access to conventional health services, recorded by the low level of education, poverty, and socio-cultural aspects. The plants are used to treat the most frequent diseases in the region. Keywords: ethnobotany; medicinal plants; Cabo Delgado - Mozambique.

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Ichsan, Ilmi Zajuli, Diana Vivanti Sigit, Rizhal Hendi Ristanto, Ilena Amalia Luthfi, Dewi Robiatun Muharomah, and Muhammad Efendi. "STUDENTS ATTITUDE TO CONSERVE MEDICINAL PLANTS AND ENVIRONMENT IN CIPANAS: PROFILE AND COMPARATIVE ANALYSIS." IJIET (International Journal of Indonesian Education and Teaching) 3, no. 2 (July 19, 2019): 149–56. http://dx.doi.org/10.24071/ijiet.v3i2.1935.

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Students' awareness in conserving medicinal plants and the environment is still the focus of discussion among educators. Especially in students at vocational school levels who do not receive comprehensive Biology learning. The purpose of this study was to measure students' attitudes in conserving medicinal plants and the environment. The research method used is descriptive method with survey techniques. The study was conducted in March-April 2019 at Cipanas State 1 Vocational High School, Cianjur, West Java, Indonesia. The sample used was selected by simple random sampling, obtained as many as 104 students divided into 44 male and 60 female students. The results showed that the average score of students' attitudes was 76.47. The indicator with the highest score is related to the program of planting medicinal plants in the home yard. While the lowest indicators relate to conservation policies for medicinal plants and the environment. This is because the information received by students in terms of conservation policy is still need to be improve. The conclusion of this study is that the scores of student attitudes regarding the conservation of medicinal plants and the environment are good, but in some indicators still need to be improved.DOI: doi.org/10.24071/ijiet.2019.030202

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Vaganova, O. A. "Recommendations for the Contents of the “Glycan Profile” Part of a Product Specification File." Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products 11, no. 4 (December 2, 2021): 273–75. http://dx.doi.org/10.30895/1991-2919-2021-11-4-273-275.

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“Glycan Profile” is a necessary part of manufacturers’ product specification files for monoclonal antibody active ingredients or final products and erythropoietin active ingredients. The expert of the Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products” of the Ministry of Health of the Russian Federation provides recommendations for a step-by-step presentation of the test procedure, which will allow applicants to align product specification files for Russian- and foreign-produced medicinal products, help experts to minimise or eliminate the need to request additional information from applicants, and will contribute to timely batch release of medicinal products.

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Vasilenko, G. F., L. M. Krasnykh, M. V. Zhuravleva, A. B. Prokofiev, G. I. Gorodetskaya, V. V. Smirnov, and N. D. Bunyatyan. "Comparative Dissolution Kinetics of Several Multisource Thioctic Acid Products." Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. Regulatory Research and Medicine Evaluation 12, no. 3 (July 12, 2022): 331–40. http://dx.doi.org/10.30895/1991-2919-2022-12-3-331-340.

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The relationship between dissolution and bioavailability is an example of the interdependency between the quality of a medicinal product and its safety and efficacy. The uniqueness of thioctic acid is that it can exist in an oxidised and a reduced form, showing lipophilic (lipoic acid) and hydrophilic (dihydrolipoic acid) properties. Bioavailability studies of thioctic acid are necessary to evaluate the expected therapeutic effect and mitigate side effects of the medicinal product.The aim of the study was to carry out equivalence dissolution testing to compare the release of thioctic acid from medicinal products produced by several manufacturers.Materials and methods: the study used a reference medicinal product and three multisource medicinal products by different manufacturers; more specifically, film-coated tablets containing 600 mg of thioctic acid. The experiment was carried out in dissolution media at pH of 6.8±0.05 and 1.2±0.05. Statistical analysis was performed by calculating the average amounts of the substance dissolved, the standard deviation (SD), and the relative standard deviation (RSD, %) using Microsoft Office Excel 2007.Results: The authors chose the testing conditions (dissolution media pH values of 6.8±0.05 and 1.2±0.05) taking into account the nature and characteristics of thioctic acid. The comparison of thioctic acid release profiles based on the calculation of the similarity factor (f2) showed that the dissolution profiles of multisource medicinal products 2 and 3 at pH 6.8 were equivalent to that of the reference medicinal product (more than 85% of the active pharmaceutical ingredient released within 15 minutes) and the dissolution profile of multisource medicinal product 1 was not equivalent to it (with f2 of 28).Conclusions: the established differences in the rate and degree of active ingredient release from the studied medicinal products may indicate possible differences in their pharmacological effectiveness in vivo.

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Konieczynski, Pawel, Monika Gappa, Marek Wesolowski, Edgar Pinto, and Agostinho Almeida. "Trace Elements in Medicinal Plants Traditionally Used in the Treatment of Diabetes—Do They Have a Role in the Claimed Therapeutic Effect?" Foods 11, no. 5 (February 24, 2022): 667. http://dx.doi.org/10.3390/foods11050667.

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Background: Medicinal plants are often used in the treatment of diabetes mellitus, although knowledge about their mode of action and the substances responsible for their antidiabetic potential is limited. It is well known that some trace elements play a role in glucose metabolism and insulin action. Thus, a particular trace elements profile could be associated with the antidiabetic properties observed for some medicinal plants. Methods: Infusions (n = 102) prepared from commercial herbal products (n = 34) containing medicinal plants indicated for the treatment of diabetes (n = 16 different plant species) and infusions (n = 60) prepared from commercial herbal products (n = 20) containing medicinal plants without such an indication (n = 7 different plant species) were analyzed by ICP-MS for their trace elements content. Results: In both groups, results varied significantly between different medicinal plants and also between different origins (brands) of the same medicinal plant. Significant differences (p < 0.05) between the two groups were found for nine elements, including four trace elements related to glucose metabolism (Mn, B, V, and Se), but with lower median contents in the group of medicinal plants for diabetes. Conclusions: Except for some particular species (e.g., Myrtilli folium) in which the trace element Mn may play a role in its antidiabetic effect, globally, a direct association between the claimed antidiabetic properties and a specific trace element profile of the studied medicinal plants was not evident.

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Cunningham, Francis, and Fabio S. Menezes. "Ethnopharmacology in Dublin: surveys on the medicinal plants use profile." Revista Brasileira de Farmacognosia 21, no. 5 (October 2011): 814–17. http://dx.doi.org/10.1590/s0102-695x2011005000141.

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Pasca, Claudia, Liviu Alexandru Marghitas, Daniel Severus Dezmirean, Otilia Bobiș, Victorita Bonta, Tania Mihăiescu, Flore Chirila, and Nicodim Fit. "MINERAL PROFILE EVOLUTION OF SOME MEDICINAL PLANTS WITH ANTIBACTERIAL EFFECTS." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies 73, no. 2 (November 28, 2016): 223. http://dx.doi.org/10.15835/buasvmcn-asb:12295.

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Individual minerals and antibacterial activity were investigated in 5 medicinal plants (pot marigold - Calendula officinalis, burdock - Arctium lappa, celandine - Chelidonium majus, basil- Ocimum basilicum, thyme - Thymus vulgaris) using Atomic Absorption Spectroscopy (AAS) technique and antibiogram method. The antibacterial susceptibility has been evaluated over 12 strains isolated from milk microflora, belonging to Staphylococcus, Vibrio, Serratia and Bacillus genera. The obtained results show the best antibacterial effect with Arctium lappa ethanol extracts, having inhibition areas of 6.3 to 17.5 mm, with an average of 9.0 mm and the highest determined mineral being Calcium. The results obtained open the prospect of using these medicinal plants as an alternative to be used for the control and cure of some mineral deficiencies or for preventing various diseases of the animals.

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Jain, Sunyana, Prem Prakash Yadav, Vikrant Gill, Neeru Vasudeva, and Neelam Singla. "Terminalia arjuna a sacred medicinal plant: phytochemical and pharmacological profile." Phytochemistry Reviews 8, no. 2 (April 24, 2009): 491–502. http://dx.doi.org/10.1007/s11101-009-9134-8.

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R, Roopa, and Mruthunjaya Kenganora. "Physicochemical properties and Lipid profile of Jyotishmati (Celastrus Paniculatus)." Journal of Pharmacological and Pharmaceutical Research 1, no. 1 (2023): 1. http://dx.doi.org/10.5455/jppr.20230712051611.

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Since prehistoric times, medicinal plants have been discovered and used in ayurvedic and traditional medicine practice. Medicinal plants contain numerous chemical compound which acts as preventive, curative, protective agent against various disease. One of the medicinal plants used for memory enhancement is Celastrus paniculatus (CP), which belongs to the family Celastracea. CP is also called as Jyotishmati or Malkangani in ayurveda and Sanskrit. CP is used in ancient traditional medical treatment for various ailments. Celastrus paniculatus contains phytochemicals, phospholipids, nutrients which are remarked to have distinct health benefit. Role of phospholipids embarked its potency in preventing and treating neurological diseases. The objective of the current study is to evaluate CP seeds for its physicochemical and pharmacognostical, properties including fatty acid composition and estimation of important phospholipids such as phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Physicochemical evaluation was done for seeds and pharmacognostical analysis was done for seed oil. One of the important observations found was absence of phospholipids viz. PC and PE. Saponification value was found to be 284 and acid value of oil was found to be less than 2. The results obtained will serve as parameters for the standardization of seeds and fixed oil obtained from seeds. Furthermore, the results will remark as a potential nutraceutical and economical utilisation of CP seeds as a new source of edible oils and to treat dementia, Alzheimer’s disease, Parkinson disease etc.

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Romanova, O. L. "Drug-induced toxicodermia as implication of a drug disease." Scientific Notes of the I. P. Pavlov St. Petersburg State Medical University 22, no. 3 (September 30, 2015): 14–16. http://dx.doi.org/10.24884/1607-4181-2015-22-3-14-16.

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Toxicodermia belongs to the widespread and serious types of adverse reactions to medicines, affects doctors of all specialties and medical institutions of any profile. The risk of development of a toxicodermia for the majority of medicinal preparations makes 20% of all medicinal complications.

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SumitKArora, MaviyaHussain, SubhashRYende, KeshavMoharir, Vipinchandra Pande, and Abhay Ittadwar. "Bauhinia purpurea: An Updated Pharmacological Profile." Journal of Ayurvedic and Herbal Medicine 6, no. 2 (June 19, 2020): 81–85. http://dx.doi.org/10.31254/jahm.2020.6213.

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Bauhinia purpurea (B. purpurea) (family: Fabaceae) commonly called as butter fly tree has vast medicinal uses and remarkable pharmacological potential. Various phytoconstituents, extracts and parts of this plant were possess significant pharmacological activities such as cardiac activity, antifungal, wound healing, antidiabetic, antiulcer, antioxidant, antinociceptive, hepatoprotective, nephroprotective, antidiarrhoeal, anti-inflammatory, antipyretic, analgesic, antimalarial, gastro protective and cytoprotective activity. The present study emphasizes the overview of recent studies and/or updates on pharmacological potential of B. purpurea.

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Morabad, Rajeshwari B., and Sharangouda J. Patil. "ELEMENTAL PROFILE ANALYSIS OF SOME INDIAN TRADITIONAL MEDICINAL SPICE PLANTS OF, BELLARI DISTRICT, KARNATAKA USING AAS TECHNIQUE." International Journal of Current Pharmaceutical Research 9, no. 1 (December 31, 2016): 59. http://dx.doi.org/10.22159/ijcpr.2017v9i1.16609.

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Objective: Karnataka (India) is the darling child of nature where about 722 medicinal plants are available. Ions of different metal elements have an important role in both the reactions. Few elements are essential to the body as nutrients called minerals. Present study deals with trace element analysis was carried out in Ballari district, Karnataka, India.Methods: 0.25g each of the powdered medicinal plant spice seeds samples digested in 6.5 ml of acid solution to study the trace element like Mn, Fe, Cu, Zn, Cd, and Cr in Coriander seeds, Ajwain seeds, Pepper seeds, Cumin seeds and Sweet cumin seeds at ppm levels were figured out by using AAS analysis.Results: Analysed trace mineral contents of these spice plants resulted highest level of Manganese is 1.92 ppm, Ferrous is 3.69 ppm and in Chromium is 0.0980 ppm in Ajwain seeds, Copper is 0.42 ppm in Coriander seeds, Zinc is 3.02 ppm and Cadmium is 0.0070 ppm in Sweet cumin seeds and lowest were found Mn is 0.65 ppm, Fe is 2.43 ppm in Coriander seeds, Cu is 0.15 ppm in Cumin seeds, Zn is 1.64 ppm in Pepper seeds, Cd is 0.0018 in Ajwain seeds and Cr is 0.0669 ppm in Sweet cumin seeds were studied in (n=3 ppm) all the sample selected spice seeds by AAS and suggests that the monitoring of trace elements in these medicinal plants does not exceed the limiting values set by World Health Organization to use it as a medicinal application.Conclusion: These Indian traditional medicinal spice plants can be safely used for food and medicinal purposes.Keywords: Medicinal Plants, Spices, AAS, Trace elements, Microelements

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Patil, Sayali T., Monika S. Mane, Kshitija S. Desai, Satyajeet R. Jagdale, Pankaj A. Jadhav, and Harshada A. Patil. "Co-Crystallization: Approaches, Characterization and Applications in Drug Delivery." Journal of Pharmaceutical Technology, Research and Management 10, no. 2 (November 10, 2022): 141–49. http://dx.doi.org/10.15415/jptrm.2022.102004.

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Co-crystals play a significant role in the pharmaceutical sector. Medicinal co crystals are multicomponent systems with at least one active therapeutic ingredient and the rest of the constituents being pharmaceutically acceptable. Co crystallization of a medicinal material with a coformer is a potential and growing method for improving pharmaceutical performance in areas such as solubility, dissolution profile, pharmacokinetics, and stability.. A key barrier to developing novel API compounds is poor bio availability and water solubility, which can limit the effectiveness of new drugs or prevent their approval for the market. In terms of the significant enhancement in solubility profiles compared to the single- active pharmaceutical ingredients, co-crystals provide a distinct and competitive edge over other traditional approaches.

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Ivanišová, Eva, Dajana Vasková, Grzegorz Zagula, Dzmitry Grynshpan, Tatsiana Aleksandrovna Savitskaya, and Miroslava Kačániová. "Phytochemical profile and biological activity of selected kind of medicinal herbs." Potravinarstvo Slovak Journal of Food Sciences 14 (July 28, 2020): 573–79. http://dx.doi.org/10.5219/1370.

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Medicinal herbs are used due to their health benefits, a special aroma, taste and are considered as one of the richest sources of bioactive compounds. The present study aimed to determine antioxidant activity (DPPH and phosphomolybdenum method), a total polyphenol (using Folin-Ciocalteu reagent), flavonoid (aluminium chloride method), phenolic acid content (using Arnov reagent), antimicrobial activity (disc diffusion method) and chemical composition (ICP-OES instrument) of medicinal herbs (ginger, comfrey, valerian, chicory, horseradish, and ramsons) grown in Slovak republic. Antioxidant activity by DPPH method ranged from 0.61 (ramsons) to 3.62 (ginger) mg TEAC per g of dry matter (TEAC – Trolox equivalent antioxidant capacity); by phosphomolybdenum method from 66.67 (valerian) to 204.14 (ginger) mg TEAC per g of dry matter. Total polyphenol content ranged from 4.37 (comfrey) to 13.19 (ramsons) GAE per g of dry matter (GAE – gallic acid equivalent); total flavonoid content from 1.07 (chicory) to 47.55 (ramsons) QE per g of dry matter (QE – quercetin equivalent) and total phenolic acid content from 0.99 (horseradish) to 9.77 (ginger) CAE per g of dry matter (CAE – caffeic acid equivalent). In a sample of ginger was detected the highest antimicrobial activity against Bacillus cereus CCM 7934 (5 mm). Among the mineral compounds – in all observed samples were dominated (mg.100g-1) of potassium, phosphor, magnesium, and calcium. The amount of cadmium, chrome, and lead in observed samples was detected only in a trace amount, so our results reveal that the medicinal herbs do not represent in this study a potential health risk regarding the content of toxic elements. The consumption and using of medicinal plants as a part of the food mode of consumers due to health benefits is recommended.

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Gichuki, Duncan Kiragu, Qingyun Li, Yujun Hou, Yuanshuang Liu, Mengxue Ma, Huimin Zhou, Chen Xu, et al. "Characterization of Flavonoids and Transcripts Involved in Their Biosynthesis in Different Organs of Cissus rotundifolia Lam." Metabolites 11, no. 11 (October 28, 2021): 741. http://dx.doi.org/10.3390/metabo11110741.

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Cissus rotundifolia Lam. is used as a medicinal herb and vegetable. Flavonoids are the major components for the therapeutic effects. However, flavonoids constituents and expression profiles of related genes in C. rotundifolia organs are unknown. Colorimetric assay showed the highest flavonoid concentration in roots compared to the stem and leaf. Widely target-based metabolome analysis allowed tentative identification of 199 compounds in three organs. Flavonols and flavones were the dominant flavonoids subclasses. Among the metabolites, 171 were common in the three organs. Unique accumulation profile was observed in the root while the stem and leaf exhibited relatively similar patterns. In the root, six unique compounds (jaceosidin, licoagrochalcone D, 8-prenylkaempferol, hesperetin 7-O-(6″malonyl) glucoside, aureusidin, apigenin-4′-O-rhamnoside) that are used for medicinal purposes were detected. In total, 18,427 expressed genes were identified from transcriptome of the three organs covering about 60% of annotated genes in C. rotundifolia genome. Fourteen gene families, including 52 members involved in the main pathway of flavonoids biosynthesis, were identified. Their expression could be found in at least one organ. Most of the genes were highly expressed in roots compared to other organs, coinciding with the metabolites profile. The findings provide fundamental data for exploration of metabolites biosynthesis in C. rotundifolia and diversification of parts used for medicinal purposes.

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da Matta, Rosana, Jesse Lahos Borges, Ulisses Nilo Landi, Lidiane Nunes Barbosa, Amandha Lara, Luciana Kazue Otutumi, Antônio Sergio Ferraudo, and Daniela Dib Gonçalves. "Ethno-epidemiological study of medicinal products and medicinal plants use among pregnant women." Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 20, no. 1 (2021): 71–80. http://dx.doi.org/10.37360/blacpma.21.20.1.6.

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The objective of this study was to examine the profile of pregnant women who visited the Unified Health System of the municipality of Umuarama/PR and to analyze their use of drugs categorized as D and X according to the United States Food and Drug Administration FDA and contraindicated medicinal plants for evaluating the potential gestational risks.A cross-sectional ethnoepidemiological study using a questionnaire was conducted among 500 pregnant women from January to May 2017. According to the pregnant women, during the prenatal period, 67.8% did not receive information on the use of medicinal plants and 26.6% used contraindicated plants. Among the drugs used, 12.2% belonged to category "D" (anticonvulsants), and 2.4% belonged to category "X" (hormonal contraceptives). This work highlights the need to expand health promotion activities to the basic units and implement protocols and technical guidance tools as well as training of pharmaceutical professionals to educate the population on the risk of these drugs during pregnancy.

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N, Sunil Kumar K., Divya K. G, Susikumar S, Abdul Khader S, and Senthilkumar M. "Comprehensive Pharmacognostical Profile of Drynaria quercifolia (L.) J. Sm." International Journal of Ayurvedic Medicine 11, no. 4 (December 9, 2020): 672–78. http://dx.doi.org/10.47552/ijam.v11i4.1657.

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Pteridophytes are gaining importance as therapeutic agents due to the presence of various phytochemicals and their promising bioactivities. Drynaria quercifolia (L.) J. Sm., a Polypodiaceae member is endowed with numerous medicinal properties and finds wide usage in ethno as well as traditional medicines. The rhizome of D. quercifolia (L.) J. Sm. was subjected to macro-microscopic, physicochemical, phytochemical and HPTLC analysis to derive a standard for this drug. The microscopic detailing showed a wavy outline due to the presence of ridges and furrows and a broad ground tissue with diffusely arranged steles. The powdered drug showed trichomes, stellar tissue and silica crystals while the physicochemical and phytochemical screenings gave substantial values of different parameters. The rhizome extracts were subjected to HPTLC studies with Linomat 5 TLC applicator and diagnostic peaks were recorded under UV 254 nm, 366 nm and 620 nm. The study put forward an exclusive identity profile of this medicinal rhizome.

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Shubnikova, E. V., T. M. Bukatina, A. A. Druzhinina, E. O. Zhuravleva, G. V. Kutekhova, and N. Yu Velts. "Safety of Antibacterial and Antiprotozoal Medicinal Products." Safety and Risk of Pharmacotherapy 10, no. 2 (June 2, 2022): 196–99. http://dx.doi.org/10.30895/2312-7821-2022-10-2-196-199.

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The experts of the Scientific Centre for Expert Evaluation of Medicinal Products analysed administrative decisions of foreign regulatory authorities on the recalls of antibacterial and antiprotozoal medicinal products and/or the need for labelling updates due to changes in the safety profile. The analysis revealed 16 decisions containing information on the following medicines registered in Russia: ertapenem, сeftriaxone, cefazolin, аmoxicillin, сefoperazone+sulbactam, piperacillin+tazobactam, сlindamycin, teicoplanin, rifampin, co-trimoxazole, hydroxychloroquine.

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Fristiohady, Adryan, Rathapon Asasutjarit, La Ode Muh Julian Purnama, Sewan Theeramunkong, Wirhamsah Al-Ramadan, Lidya Agriningsih Haruna, Nur Syifa Rahmatika, Syarul Nataqain Baharum, and I. Sahidin. "Phytochemical Profile and Anticancer Activity from Medicinal Plants Against Melanoma Skin Cancer: A Review." Indonesian Journal of Science and Technology 7, no. 3 (October 10, 2022): 405–70. http://dx.doi.org/10.17509/ijost.v7i3.51325.

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Melanoma skin cancer is a malignant melanocyte tumor considered the most invasive and dangerous skin cancer, with an average five-year survival rate of less than 5% after metastasis. Thus, a new strategy for preventing and treating cancer from the natural product is required. Medicinal plants are the potential as an alternative against cancer. This review article aims to determine natural products from medicinal plants which have the potential as an anticancer in melanoma skin cancer in vitro and in vivo. 40 plants have been selected based on the selection criteria for anticancer compounds. In vitro studies showed that the plant can reduce cell viability through cell cycle inhibition and apoptosis induction and inhibit angiogenesis, invasion, and metastasis in human melanoma skin cancer. Therefore, further research is required to explore more plants, especially medicinal plants, their active compounds, and the mechanism of anticancer action to be used as standard herbal medicines.

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Asiminicesei, Dana-Mihaela, Daniela Ionela Fertu, and Maria Gavrilescu. "Impact of Heavy Metal Pollution in the Environment on the Metabolic Profile of Medicinal Plants and Their Therapeutic Potential." Plants 13, no. 6 (March 21, 2024): 913. http://dx.doi.org/10.3390/plants13060913.

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The paper provides a comprehensive examination of heavy metal stress on medicinal plants, focusing on its impact on antioxidant capacity and biosynthetic pathways critical to their therapeutic potential. It explores the complex relationship between heavy metals and the physiological and biochemical responses of medicinal plants, highlighting how metal stress disrupts biosynthetic pathways, altering concentrations of secondary metabolites. This disruption may compromise the overall quality and efficacy of medicinal plants, requiring a holistic understanding of its cumulative impacts. Furthermore, the study discusses the potential of targeted genetic editing to enhance plant resilience against heavy metal stress by manipulating genes associated with antioxidant defenses. This approach represents a promising frontier in safeguarding medicinal plants in metal-contaminated environments. Additionally, the research investigates the role of phytohormone signaling in plant adaptive mechanisms to heavy metal stress, revealing its influence on biochemical and physiological responses, thereby adding complexity to plant adaptation. The study underscores the importance of innovative technologies and global cooperation in protecting medicinal plants’ therapeutic potential and highlights the need for mitigation strategies to address heavy metal contamination effectively.

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Lomate, Krushna A., Krishna Murthy, Vishal S. Adak, and Rajkumar V. V. Shete. "A review on phytochemical and pharmacological values of Aegle marmelos." Journal of Drug Delivery and Therapeutics 11, no. 2-S (April 15, 2021): 162–66. http://dx.doi.org/10.22270/jddt.v11i2-s.4645.

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India is the largest producer of medicinal plants and is rightly referred to as "the World's Botanical Garden." Medicinal plants play a key role in the health and vitality of humans and animals alike. Researchers have been attempting to recognize and validate plant-derived substances for the treatment of various diseases that promote compounds for health and nutrition for the past few years. Bael is a common plant that originated in India (Aegle marmelos). According to a study of the literature, entire parts of the plant, such as roots, barks, leaves, fruits, seeds, and flowers, are used to treat various diseases. Bangladesh, Indonesia, China, and other Asian countries, for example, it is a spiritual, religious, and medicinal plant that can be found all over the world. It has a number of therapeutic applications. Nowadays, various products from various parts of the plant are prepared. The biological profile, botanical description, physicochemical parameters, conventional uses, therapeutic applications and creative aspects are included in this study. The purpose of the present analysis is to compile the general chemical profile, both medicinal and economic value, value-added items such as juice, jam and toffee, and other uses of Aegle marmelos. Keywords: Aegle marmelos, Rutaceae, Medicinal Values

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Gaspar Amaral, Luciene F., and Iolanda M. Fierro. "Profile of medicinal plants utilization through patent documents: The andiroba example." Revista Brasileira de Farmacognosia 23, no. 4 (July 2013): 716–22. http://dx.doi.org/10.1590/s0102-695x2013005000046.

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Noviyanti, Noviyanti, Raden Aldizal Mahendra Rizkio Samudra, Farid Perdana, and Diennisa Izzati Thahira. "Profile of Characteristic and Secondary Metabolite Content Alstonia Scholaris Medicinal Plants." Jurnal Aisyah : Jurnal Ilmu Kesehatan 6, no. 1 (March 22, 2021): 151–58. http://dx.doi.org/10.30604/jika.v6i1.459.

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V, MOHOLKAR, JADGE R, and NAGOBA N. "Pharmacokinetic Profile of Polyherbal Tablets Comprising Extracts of Antidiabetic Medicinal Plants." Journal of Complementary Medicine Research 12, no. 3 (2021): 1. http://dx.doi.org/10.5455/jcmr.2021.12.03.01.

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Shaheen, Nazma, Avonti Basak Tukun, Saiful Islam, Kazi Turjaun Akhter, Md Sujan Hossen, and Thingnganing Longvah. "Polyphenols profile and antioxidant capacity of selected medicinal plants of Bangladesh." Bioresearch Communications 7, no. 1 (June 23, 2021): 947–54. http://dx.doi.org/10.3329/brc.v7i1.54252.

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Polyphenols in many plant foods have received a great deal of attention due to their biological potency and postulated protective role against certain non-communicable diseases like cancer, neurodegenerative disease, and cardiovascular disease. The current study focuses on 15 indigenous plants which are traditionally being used for medicinal and other purposes in Bangladesh. Specifically, this study aimed to determine the total phenolic content (TPC), profile the polyphenolic composition, and assess the antioxidant capacity (AC) of water and methanol extracts derived from these plants. The TPC was estimated using the Folin-Ciocalteu method, and DPPH inhibition was used to assess the AC. HPLC-centered simultaneous determination method of polyphenols was employed to identify and quantify individual polyphenolic compounds. TPC content (expressed as mg GAE/100 g FW) ranged from 15.5 (Zanthoxylum rhetsa) to 276.9 (Moringa oleifera). The lowest IC50 in the water and methanol extracts were shown by Moringa oleifera and Zanthoxylum rhetsa respectively and they also exhibited high free radical scavenging activity in the corresponding solvents (91.9% and 92.9% DPPH inhibition by Moringa oleifera and Zanthoxylum rhetsa respectively). The lowest DPPH inhibition was observed in Alternanthera philoxeroides (29.8%) and Spilanthes calva (24.5%) in the water and methanol extracts respectively. Ten polyphenols (coumaric acid, chlorogenic acid, caffeic acid, apigenin, apigenin-7-O-neohesperidoside, quercetin-3-β-D-glucoside, luteolin, quercetin-3-O-β-D-glucopyranoside, isorhamnetin and kaempferol) were initially identified and subsequently quantified in the plant extracts. Spilanthes calva, Moringa oleifera, Oxalis corniculata, and Piper retrofractum contained the highest amount of coumaric acid and chlorogenic acid, apigenin, caffeic acid and apigenin-7-O-neohesperidoside respectively. Senna tora had the greatest amount of kaempferol, quercetin-3-β-D-glucoside, and isorhamnetin whereas luteolin and quercetin-3-O-β-D-glucopyranoside were observed to be the maximum in Alternanthera sessilis. To conclude, Moringa oleifera and Senna tora with high percentage of DPPH inhibition and low IC50 were the most potent antioxidant sources among the analyzed samples. Bioresearch Commu. 7(1): 947-954, 2021 (January)

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Tewari, Sheela. "The Medicinal Plants Economy of South Africa: Profile and Future Perspectives." Journal of Interdisciplinary Economics 15, no. 3-4 (July 2004): 293–300. http://dx.doi.org/10.1177/02601079x04001500304.

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Vitas, Jasmina, Stefan Vukmanovic, Jelena Cakarevic, Ljiljana Popovic, and Radomir Malbasa. "Kombucha fermentation of six medicinal herbs: Chemical profile and biological activity." Chemical Industry and Chemical Engineering Quarterly 26, no. 2 (2020): 157–70. http://dx.doi.org/10.2298/ciceq190708034v.

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Bioactive properties, as well as chemical composition and sensory characteristics of traditional and alternative kombucha broths were examined. Samples were produced by adding 10% of kombucha starter to sweetened (7% sucrose) decocts of black and green teas (traditional substrates) and infusions of winter savory (Satureja montana), peppermint (Mentha?piperita), stinging nettle (Urtica dioica), wild thyme (Thymus serpyllum), elderberry (Sambucus nigra) and quince (Cydonia oblonga), at 25?C. Fermentation lasted the shortest with elderberry (3 days) and the longest with quince (10 days). The samples with black tea and peppermint had the best sensory quality. In general, alternative products had better antioxidant activity to hydroxyl radicals than the traditional ones, reducing power and angiotensin-converting enzyme inhibitory activity. The most pronounced acetic acid content was obtained with elderberry substrate. Moreover, peppermint substrate showed the highest values both for total phenols and total flavonoids contents. Taken together, the samples produced with the alternative substrates highlighted a higher phenolic and flavonoid contents, compared to the ones obtained with the traditional substrates.

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Journal articles on the topic 'Medicinal profile'

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