Journal articles on the topic 'Medication reminder'

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1

Santo, Karla, Clara K. Chow, Aravinda Thiagalingam, Kris Rogers, John Chalmers, and Julie Redfern. "MEDication reminder APPs to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study: a randomised controlled trial protocol." BMJ Open 7, no. 10 (October 2017): e017540. http://dx.doi.org/10.1136/bmjopen-2017-017540.

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IntroductionThe growing number of smartphone health applications available in the app stores makes these apps a promising tool to help reduce the global problem of non-adherence to long-term medications. However, to date, there is limited evidence that available medication reminder apps are effective. This study aims to determine the impact of medication reminder apps on adherence to cardiovascular medication when compared with usual care for people with coronary heart disease (CHD) and to determine whether an advanced app compared with a basic app is associated with higher adherence.Methods and analysisRandomised controlled trial with follow-up at 3 months to evaluate the feasibility and effectiveness of medication reminder apps on medication adherence compared with usual care. An estimated sample size of 156 patients with CHD will be randomised to one of three groups (usual care group, basic medication reminder app group and advanced medication reminder app group). The usual care group will receive standard care for CHD with no access to a medication reminder app. The basic medication reminder app group will have access to a medication reminder app with a basic feature of providing simple daily reminders with no interactivity. The advanced medication reminder app group will have access to a medication reminder app with additional interactive and customisable features. The primary outcome is medication adherence measured by the eight-item Morisky Medication Adherence Scale at 3 months. Secondary outcomes include clinical measurements of blood pressure and cholesterol levels, and medication knowledge. A process evaluation will also be performed to assess the feasibility of the intervention by evaluating the acceptability, utility and engagement with the apps.Ethics and disseminationEthical approval has been obtained from the Western Sydney Local Health Network Human Research Ethics Committee (AU/RED/HREC/1/WMEAD/3). Study findings will be disseminated via usual scientific forums.Trial registration numberACTRN12616000661471; Pre-results
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Shade, Marcia, Kyle Rector, and Kevin Kupzyk. "VERIFICATION OF PAIN MEDICATION ADHERENCE IN OLDER ADULTS USING INTERACTIVE VOICE REMINDERS." Innovation in Aging 3, Supplement_1 (November 2019): S926. http://dx.doi.org/10.1093/geroni/igz038.3371.

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Abstract Adherence to analgesics needs to be monitored to ensure optimal pain management and avert adverse events among older adults. mHealth reminders may encourage adherence behavior, but it is unclear if medication use ensues following the reminder. The purpose of this study was to trial the use of medication event monitoring to verify the initiation of scheduled pain medication after an mHealth reminder. Methods: N=15 adults 55 and older created Google Assistant reminders to take their scheduled pain medication and write in a pain diary. A sub sample of n= 5 participants used a Medication Event Monitoring System Cap with their scheduled pain medications over 4 weeks. Data were collected on demographics, pain severity, and medication adherence. Descriptive statistics were performed. Results: Five women with ages ranging from 56-80 years, reported pain in multiple body locations. Pain severity on average was rated at 4 and at its worst 7; with pain relief ranging from 50-90%. Adherence percentages ranged from 82% to 100%. The overall latency was M = 55 min, SD = 100 min. The average latencies varied among the 5 participants; the shortest average time was 17 minutes and the longest average time was 4.5 hours. Only 15% of pain medications were taken within 5 minutes and 64% within 30 minutes of the interactive voice assistant reminder. Conclusions: It is important to ensure a behavioral intervention promotes the desired outcome. Medication event monitoring systems may help to identify non adherent behaviors when using mHealth interventions to promote pain medication adherence.
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Wolters, Maria K., Christine Johnson, Pauline E. Campbell, Christine G. DePlacido, and Brian McKinstry. "Can older people remember medication reminders presented using synthetic speech?" Journal of the American Medical Informatics Association 22, no. 1 (July 30, 2014): 35–42. http://dx.doi.org/10.1136/amiajnl-2014-002820.

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Abstract Reminders are often part of interventions to help older people adhere to complicated medication regimes. Computer-generated (synthetic) speech is ideal for tailoring reminders to different medication regimes. Since synthetic speech may be less intelligible than human speech, in particular under difficult listening conditions, we assessed how well older people can recall synthetic speech reminders for medications. 44 participants aged 50–80 with no cognitive impairment recalled reminders for one or four medications after a short distraction. We varied background noise, speech quality, and message design. Reminders were presented using a human voice and two synthetic voices. Data were analyzed using generalized linear mixed models. Reminder recall was satisfactory if reminders were restricted to one familiar medication, regardless of the voice used. Repeating medication names supported recall of lists of medications. We conclude that spoken reminders should build on familiar information and be integrated with other adherence support measures.
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Alaspure, Sonali Subhash, and Dr A. P. Thakare. "Linux Based Speaking Medication Reminder Project." International Journal of Trend in Scientific Research and Development Volume-2, Issue-3 (April 30, 2018): 2285–88. http://dx.doi.org/10.31142/ijtsrd12726.

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Santo, Karla, Anna Singleton, Clara K. Chow, and Julie Redfern. "Evaluating Reach, Acceptability, Utility, and Engagement with An App-Based Intervention to Improve Medication Adherence in Patients with Coronary Heart Disease in the MedApp-CHD Study: A Mixed-Methods Evaluation." Medical Sciences 7, no. 6 (June 4, 2019): 68. http://dx.doi.org/10.3390/medsci7060068.

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Objective: The aim of this study was to assess the reach, acceptability, utility, and engagement with the apps that were used in the MEDication reminder APPlications (apps) to improve medication adherence in Coronary Heart Disease (MedApp-CHD) study, a randomised clinical trial to improve medication adherence, using a mixed-methods approach. Methods: The MedApp-CHD study randomised 163 patients with coronary heart disease (CHD) to one of three groups: (i) usual care (n = 56), (ii) a basic medication reminder app (n = 54), or (iii) an advanced medication reminder app (n = 53). For this mixed-methods evaluation, the data sources included patient screening logs, feedback questionnaires collected at three-month follow-up, focus groups discussions, and analytical data from the app software. Results: Ninety-four percent (98/104) of participants who received a medication reminder app completed the three-month feedback questionnaire and 15 participated in the focus group discussions. The themes that were identified included that participants (i) found the medication reminders useful in reminding them to take the medications on the correct time every day, (ii) liked having the medication list as an easily-accessible record of medications’ names and dosages, (iii) reported being likely to continue to use the apps after the study completion, (iv) would be likely to recommend the apps to their family and friends, and (v) those who used the clinical measurements feature found it useful as a tool to track and graph the blood pressure and glucose levels over time (especially those with diabetes and/or hypertension). In addition, analytical data from the app software demonstrated that the participants used the medication-related features more than the clinical measurements feature. Furthermore, data from the patient screening logs showed that the main reason for exclusion, other than not meeting the CHD criteria, was not having a suitable smartphone, and those that were excluded for this reason were older and had a higher proportion of females than those enrolled in the study. Conclusion: This study provides important insights regarding the features that are most useful in apps that aim to improve medication adherence. This mixed-methods evaluation suggests that, currently, young male patients with CHD are more likely to use such apps, that the apps were well-accepted and useful in reminding the patients to take the medications, and that the patients were engaged in regularly using the apps.
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Stuck, Rachel E., Amy W. Chong, L. Mitzner Tracy, and Wendy A. Rogers. "Medication Management Apps: Usable by Older Adults?" Proceedings of the Human Factors and Ergonomics Society Annual Meeting 61, no. 1 (September 2017): 1141–44. http://dx.doi.org/10.1177/1541931213601769.

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For older adults, managing medications can be a burden and could lead to medication non-adherence. To decrease risks associated with medication non-adherence, healthcare providers may recommend medication reminder apps as an assistive tool. However, these apps are often not designed with consideration of older adults’ needs, capabilities, and limitations. To identify whether available apps are suitable for older adults, we conducted an in-depth cognitive walkthrough and a heuristic evaluation of the most commonly downloaded medication reminder app. Findings revealed three main issues: 1) difficulty in navigation, 2) poor visibility, and 3) a lack of transparency. We also selected the top five downloaded medication reminder apps and categorized user reviews to assess app functionality and usability problems. The results of our analysis provide guidance for app design for older adult users to provide effective tools for managing medications and supporting patient/user health.
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Rattanayotin, Jakrapong, and Asst Prof Dr Vajirasak Vanijja. "Designing and Developing Android Application for Medication Reminder to Improve Treatment Efficiency of Stroke Patient." KnE Social Sciences 3, no. 1 (January 15, 2018): 143. http://dx.doi.org/10.18502/kss.v3i1.1403.

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Stroke patients often experience problems of taking medications due to forgetfulness, a number of medications causing confusion to take, or even the side effects making the patients refuse to take medications resulting in ineffective treatment. In this study, the researchers study and develop information technology in the form of Android application in order to educate and remind the stroke patients to take medications by developing a prototype system called DCMed. The research finds that the stroke patients in the experimental group using DCMed system are more interested and complied with taking medications accounting for 42.86%. Moreover, the patients can take medications more timely than those in the control group at the significant level of 0.05.Keywords: stroke patient, medication discontinuation, medication reminder system, Android application, web application, medication compliance, IMB Model
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Kamimura, T., and H. Ito. "Glycemic control in a 79-year-old female with mild cognitive impairment using a medication reminder device: a case report." International Psychogeriatrics 26, no. 6 (January 2, 2014): 1045–48. http://dx.doi.org/10.1017/s1041610213002408.

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ABSTRACTA 79-year-old female with type 2 diabetes and mild cognitive impairment (Clinical Dementia Rating score of 0.5) was supported with medication with regard to the daily requirements using a medication reminder device. Use of this device not only improved her medication adherence, hemoglobin A1c level, and self-confidence but also reduced caregiver's burden. For elderly patients with such diseases, loading the device with medication, providing advance notice before mechanical reminders for a short period after the device's activation, monitoring unused medication, and adjusting the timing of reminders according to users’ daily routine, seemed to facilitate daily use of the device.
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Mardianto, Rudy. "Aplikasi Pengingat Minum Obat Di Desa Sumbersuko Kecamatan Wagir Kabupaten Malang." Jurnal ABM Mengabdi 8, no. 2 (December 2, 2021): 33. http://dx.doi.org/10.31966/jam.v8i2.951.

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The people of Sumbersuko village in Wagir sub-district, Malang district, on average, already have an Android-based smartphone. The medication reminder application found on the smartphone is not yet known and used. The training program for 12 health cadres is expected that they understand and are able to use the medication reminder application well. Training is given to health cadres so that they can disseminate information to the community. The methods used in the training were lectures, discussions and trials with smartphones by health cadres. Beginning with the introduction of medication reminder applications, techniques for downloading applications and filling in drug data. The medication reminder application is important for people who are undergoing treatment for chronic diseases such as diabetes mellitus, tuberculosis, hypertension and other diseases who must take medication uninterruptedly. Medication reminder applications can improve adherence. Compliance with taking medication is one of the factors that affect the success of treatment, so the presence of this application is appropriate when applied. The alarm in the medication reminder application will help especially the elderly in Sumbersuko village. The presence of a medication reminder application is expected to improve people's quality of life and reduce mortality and morbidity
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10

Osahon, Penaere T., Lisa A. Mote, and Veronica I. Ntaji. "Assessment of the impact of medPlan®, a medication reminder mobile application, in glaucoma patients in Benin City, Nigeria." Tropical Journal of Pharmaceutical Research 19, no. 12 (March 17, 2021): 2677–82. http://dx.doi.org/10.4314/tjpr.v19i12.28.

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Purpose: To assess the impact of medPlan®, a medication reminder mobile application in glaucoma patients in Benin City, Nigeria.Methods: In a randomized control trial with 2 months follow-up period, 200 patients receiving drug therapy for glaucoma were randomized into either into a control or study group. The study group comprised participants who made use of a medication reminder mobile application, medPlan®, while the control group consisted of those patients who did not use the application. Adherence to medication was measured for all the patients in both groups. Data was collected using a carefully designed questionnaire and statistically analyzed.Results: This study recorded 100 % response rate from the participants. In the study group, 56 % were very adherent while 18 % were moderately adherent, and 26 % were non-adherent respondents as against 45 % very adherent, 13 % moderately adherent and 42 % non-adherent respondents from the control group. In addition, 78 % of those in the study group agreed that there was improvement in their medication adherence since they started using the medication reminder application. This showed a significant positive impact of the medication reminder application (p = 0.0110) on adherence to medication.Conclusion: Medication adherence was improved in glaucoma patients who used medPlan®, a smartphone medication reminder application. This study lays a foundation for further research on medication reminder mobile applications. Keywords: Glaucoma, Smartphone, Medication adherence, Impact, Medication reminder, medPlan®
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Eaton, Cyd, Margaret Comer, Cozumel Pruette, Kevin Psoter, and Kristin Riekert. "Text Messaging Adherence Intervention for Adolescents and Young Adults with Chronic Kidney Disease: Pilot Randomized Controlled Trial and Stakeholder Interviews." Journal of Medical Internet Research 22, no. 8 (August 14, 2020): e19861. http://dx.doi.org/10.2196/19861.

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Background Up to one-third of adolescents and young adults (11-21 years old) with chronic kidney disease exhibit suboptimal rates of adherence to renal-protective antihypertensive medications. Mobile health interventions may promote higher adherence to these medicines in these individuals, but empirical research is needed to inform best practices for applying these modalities. Objective In this multiphase investigation, we developed and tested a theoretically informed text messaging intervention based on the COM-B model, a well-established health intervention framework stating that capability, opportunity, and motivation interactively modify health behaviors, to improve participants’ antihypertensive medication adherence in a pilot randomized controlled trial. Qualitative data on user experiences were obtained. Methods In phase 1, intervention messages (Reminder+COM-B Message) were developed via stakeholder engagement of participants and pediatric nephrologists. In phase 2, the Reminder+COM-B Message intervention was tested against a Reminder-only Message active control condition in an 8-week pilot randomized controlled trial. The primary outcome was daily electronically monitored antihypertensive medication adherence and secondary outcomes included pre-post participant surveys of adherence self-efficacy, adherence barriers, outcome expectancies for taking medicine, and motivation for and importance of taking medicine. In phase 3, qualitative interviews related to user experiences were conducted with participants in the Reminder+COM-B Message intervention group. Results Following phase 1, 34 participants (mean age 16.59 years, 41% female, 38% African American/Black, 35% hypertension diagnosis) completed the phase 2 pilot randomized controlled trial (n=18 in the Reminder+COM-B Message intervention group, n=16 in the Reminder-only Message active control group). All participants in the Reminder+COM-B Message intervention group completed a phase 3 qualitative interview. Overall, study procedures were feasible and the Reminder+COM-B Message intervention was acceptable to the participants (eg, 15/18 participants reported reading the majority of messages sent to them, 0/18 reported that the messages reduced their desire to take medicine). Prerandomization, there were no significant group differences in the rate of change in daily adherence over time. However, postrandomization, there was a significant group by time interaction (B=.01, P=.04) in which daily adherence decreased significantly over time in the Reminder-only Message active control group but remained stable in the Reminder+COM-B Message intervention group. There were no significant differences between groups in pre-post changes in survey responses. Qualitative interviews revealed participants’ perceptions of how the Reminder+COM-B Message intervention changed adherence behavior and highlighted several areas for improving the intervention (eg, adapt messaging timing, intensity, and content to match daily adherence, send praise when medicine is taken). Conclusions The Reminder+COM-B Message intervention was feasible and acceptable to adolescents/young adults and demonstrated potential to promote participants’ daily medication adherence beyond simple reminders. Further research is needed to determine the Reminder+COM-B Message intervention’s mechanisms of adherence behavior change and to incorporate qualitative participant feedback into a modified version of this intervention to enhance its acceptability. Trial Registration ClinicalTrials.gov NCT03651596; https://clinicaltrials.gov/ct2/show/NCT03651596
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Anandaraju, Dr M. B. "Smart Medicine Reminder Box." International Journal for Research in Applied Science and Engineering Technology 9, no. VII (July 31, 2021): 2659–62. http://dx.doi.org/10.22214/ijraset.2021.36730.

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Our project's principle point is to make a Smart medication box for those clients who routinely take medicines and the solution of their medication is extremely long as it is difficult to recollect to patients and furthermore for their parental figure. Additionally Old age patients experience the ill effects of issues of neglect to take pills on appropriate time which causes certain medical problems for patients having Permanent infections like diabetes, circulatory strain, breathing issue, heart issues, malignancy sicknesses and so forth We saw these issues in emergency clinics and individuals around us who have such sort of infections and accordingly dependent on these two issues we made brilliant medication box which tackle these issues by Setting up time table of endorsed drugs through press catches as given in remedy.
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Anonymous. "Medication Reminder Watch Can Reduce Noncompliance." Journal of Psychosocial Nursing and Mental Health Services 39, no. 4 (April 2001): 21. http://dx.doi.org/10.3928/0279-3695-20010401-09.

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Tanke, Elizabeth Decker, and Von O. Leirer. "Use of Automated Telephone Reminders to Increase Elderly Patients' Adherence to Tuberculosis Medication Appointments." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 37, no. 2 (October 1993): 193–96. http://dx.doi.org/10.1177/154193129303700208.

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Elderly patients (N=617) with scheduled appointments in a public health clinic tuberculosis clinic either received or did not receive an automated telephone reminder the evening before their appointment. Patients in this population were primarily non-English speaking immigrants who received reminders in their own language. Automated reminders decreased nonadherence 21% (from 29% to 23%), and this impact did not differ across ethnic groups.
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Simkins, Candace V., and Nancy J. Wenzloff. "Evaluation of a Computerized Reminder System in the Enhancement of Patient Medication Refill Compliance." Drug Intelligence & Clinical Pharmacy 20, no. 10 (October 1986): 799–802. http://dx.doi.org/10.1177/106002808602001017.

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This study evaluated the use of a computerized patient profile combined with a reminder system to increase refill compliance of patients on cardiovascular medications. There were 311 patients randomly assigned into one of three groups. Patients in group 1 were monitored for refill compliance only. Group 2 patients received a postcard reminder; group 3 patients received a telephone call reminder. Refill compliance was monitored via the computerized patient profile system for a period of three months. Data collection included refill compliance, reasons for noncompliance, and the number of prescription medications for each patient. There was a significant difference between the overall mean rate of compliance between the control and intervention groups. An increase in refill compliance for all groups occurred over three months. There was no significant difference in compliance between the treatment groups. Overall, the medication reminder system appeared to be effective; however, modifications in the system should be pursued.
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Polenick, Courtney A., Sarah D. Stanz, Amanda N. Leggett, Donovan T. Maust, Nancy A. Hodgson, and Helen C. Kales. "Stressors and Resources Related to Medication Management: Associations With Spousal Caregivers’ Role Overload." Gerontologist 60, no. 1 (October 24, 2018): 165–73. http://dx.doi.org/10.1093/geront/gny130.

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Abstract Background and Objectives Managing medications can be stressful for spousal caregivers, but little is known about particular aspects of medication management that are most consequential for caregiving outcomes. We examined care stressors and resources related to medication management, their associations with role overload among spousal caregivers, and whether these links vary by care recipients’ number of chronic health conditions and dementia status. Research Design and Methods This cross-sectional study included 377 spousal caregivers of adults aged 65 and older from the 2011 National Health and Aging Trends Study and National Study of Caregiving. Linear regressions were estimated to evaluate how medication-related stressors (ordering medication, keeping track of medications, giving injections) and resources (medication reminder systems, shared medication management within the spousal dyad) are associated with caregivers’ role overload. Care recipients’ number of chronic health conditions and dementia status were considered as moderators. Models controlled for caregivers’ sociodemographic characteristics, chronic health conditions, and other care tasks. Results Caregivers who administered injections reported more role overload, whereas those who worked with care recipients to jointly manage medications reported less role overload. Keeping track of medications was linked to caregivers’ greater role overload when care recipients had 5 or more chronic health conditions. Finally, care recipients’ use of medication reminder systems was linked to less role overload for caregivers of a partner with dementia. Discussion and Implications Devising strategies to assist spousal caregivers in the more onerous components of medication management and promote resources that mitigate medication-related stress may improve caregiver well-being.
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Saha, Saibal Kumar, Anindita Adhikary, Ajeya Jha, and Vijay K. Mehta. "Using Food Timing as an Intervention to Improve Medication Compliance." International Journal of Reliable and Quality E-Healthcare 10, no. 3 (July 2021): 16–31. http://dx.doi.org/10.4018/ijrqeh.2021070102.

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Medication non-compliance is common among patients suffering from chronic disease. The research aims to find the effectiveness of food timing as a form of intervention to improve medication compliance. 509 patients were interviewed who were under the medication and had their treatment from Central Referral Hospital, Sikkim. The technique of probability estimates, risk difference, relative risk, and odds ratios were used to do the analysis and predictions of medication compliance when food timing was used as a form of reminder. Analysis of confidence interval at 95% ensured that the results obtained were due to the use of reminder and not by chance. The study reveals that with the help of food timing as a form of reminder, a patient has 50.2% lower odds of deferring from the scheduled time of medicine. There are 129.2% greater odds of completing the course of medication, 41.4% lower odds of missing the medication consciously, and there are 56.6% lower odds of missing the medication dose. The probability numbers indicate the effectiveness of usage of this form of reminder.
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Wu, Qiong, Zhiwei Zeng, Jun Lin, and Yiqiang Chen. "AI empowered context-aware smart system for medication adherence." International Journal of Crowd Science 1, no. 2 (June 12, 2017): 102–9. http://dx.doi.org/10.1108/ijcs-07-2017-0006.

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Purpose Poor medication adherence leads to high hospital admission rate and heavy amount of health-care cost. To cope with this problem, various electronic pillboxes have been proposed to improve the medication adherence rate. However, most of the existing electronic pillboxes use time-based reminders which may often lead to ineffective reminding if the reminders are triggered at inopportune moments, e.g. user is sleeping or eating. Design/methodology/approach In this paper, the authors propose an AI-empowered context-aware smart pillbox system. The pillbox system collects real-time sensor data from a smart home environment and analyzes the user’s contextual information through a computational abstract argumentation-based activity classifier. Findings Based on user’s different contextual states, the smart pillbox will generate reminders at appropriate time and on appropriate devices. Originality/value This paper presents a novel context-aware smart pillbox system that uses argumentation-based activity recognition and reminder generation.
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Ameta, Deepti, Kalpana Mudaliar, and Palak Patel. "Medication Reminder and Healthcare – An Android Application." International Journal of Managing Public Sector Information and Communication Technologies 6, no. 2 (June 30, 2015): 39–48. http://dx.doi.org/10.5121/ijmpict.2015.6204.

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Choudhry, Niteesh K., Alexis A. Krumme, Patrick M. Ercole, Charmaine Girdish, Angela Y. Tong, Nazleen F. Khan, Troyen A. Brennan, Olga S. Matlin, William H. Shrank, and Jessica M. Franklin. "Effect of Reminder Devices on Medication Adherence." JAMA Internal Medicine 177, no. 5 (May 1, 2017): 624. http://dx.doi.org/10.1001/jamainternmed.2016.9627.

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Isfahani, Sakineh, Asghar Ehteshami, Ebtesam Savari, and Ali Samimi. "Developing the Medication Reminder Mobile Application “Seeb”." Acta Informatica Medica 25, no. 2 (2017): 108. http://dx.doi.org/10.5455/aim.2017.25.108-111.

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Saha, Saibal Kumar, and Ajeya Jha. "Impact of reminder on medication adherence: a structural equation model, based on study in Sikkim, India." Bioscience Journal 38 (February 16, 2022): e38014. http://dx.doi.org/10.14393/bj-v38n0a2022-59087.

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The problem of medication non-adherence has persisted over decades. The rate of adherence decreases with time and improvement in health condition. When patients cannot follow their prescribed medication regime, it leads to deterioration of their health condition and increases their financial costs. This research aims to find the effect of reminder on medication adherence behaviour of patients when “Acceptance of Side Effect”, “Quality of Life” and “Medication Beliefs” act as mediators. The sample size of the research was 505. Sampling units comprised patients suffering from different diseases in Central Referral Hospital, Sikkim, India. By developing a Structural Equation Model, the effect of reminder on the mediators and adherence was analysed. The results show a significant positive association between reminder and the three mediators. Reminder has a significant positive effect on adherence (β=0.637, e=0.055, p=0.001). The effect is higher in the presence of mediators (β=0.7, e=0.037, p=0.001).
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Kupiec, Olivia, Maurita Harris, and Wendy Rogers. "Understanding Older Adults Motivations and Preferences for a Medication Adherence App." Innovation in Aging 5, Supplement_1 (December 1, 2021): 986. http://dx.doi.org/10.1093/geroni/igab046.3544.

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Abstract As the percentage of older adults with hypertension continues to increase, medication adherence remains low. However, medication adherence can potentially be improved through the use of medication reminder apps. Medication reminder apps contain numerous features that enable older adults to remember to take their medication, such as providing alerts to take their medication, reminding them when to refill their prescription, and more. Despite being aware of these apps, many older adults lack the motivation needed to use them continuously. We recruited 9 participants (60 years or older) who currently take medication for a chronic condition. Using a mixed-methods approach, we gathered quantitative survey data using the TechSAge Demographic Background, Motivation, and Behavior Change Technique Questionnaires). Qualitative data were gathered through a semi-structured interview that asked questions about general motivations and preferences in addition to engaging participants in co-designing a medication adherence app. Results from the interview were analyzed through a thematic analysis that identified comprehension and preferences of older adults in medication reminder app usage. We tested five different intrinsic motivation factors, and results indicate older adults are most motivated intrinsically due to perceived choice, perceived competence, value/usefulness, effort/importance, and pressure/tension. We also tested five factors of extrinsic motivation, and results indicate older adults are most motivated extrinsically due to introjected regulation, reward-driven, external regulation, compliance, and identification. These data provide insights to guide the design of medication reminder apps to support older adults in the self-management of their chronic conditions.
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Sammulia, Suci Fitriani, Fita Rahmawati, and Tri Murti Andayani. "PERBANDINGAN PILL BOX DAN MEDICATION CHART DALAM MENINGKATKAN KEPATUHAN DAN OUTCOME KLINIK GERIATRI KOTA BATAM." JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) 6, no. 4 (December 30, 2016): 288. http://dx.doi.org/10.22146/jmpf.358.

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Banyaknya obat yang dikonsumsi oleh pasien geriatri dengan penyakit kronis meningkatkan penurunan kepatuhan. Ada beberapa cara dalam meningkatkan kepatuhan diantaranya dengan menggunakan Pill box dan Medication reminder chart. Penelitian ini bertujuan untuk mengetahui perbandingan efektifitas penggunaan Pill box dengan Medication reminder chart dalam meningkatkan kepatuhan pasien geriatri dengan hipertensi di Kota Batam. Rancangan Penelitian ini adalah studi experimental; Randomized Controlled Trial dengan desain penelitian pre test dan post test control group. Pengambilan sampel pada penelitian ini dilakukan dengan teknik random alokasi sampling. Pasien akan dikelompokkan menjadi dua kelompok subjek yang berbeda, yaitu kelompok yang mendapat intervensi berupa Pill box dan Medication reminder chart. Data dikumpulkan secara prospektif sesuai dengan kriteria inklusi padap asien geritri rawat jalan, dengan diagnosa penyakit hipertensi di dua rumah sakit Kota Batam, penelitian dilakukan pada bulan Januari sampai April 2016. Pengukuran tingkat kepatuhan menggunakan kuesioner MMAS-8 dan pill count dan outcome klinik pasien diukur dengan melihat tekanan darah sistolik dan diastolik yang disesuaikan dengan diagnosa dokter yang tertera di rekam medik. Pengukuran dilakukan sebelum dan sesudah perlakuan. Data dianalisis secara statistik menggunakan deskripitif, uji bivariat. Hasil penelitian ini menunjukkan bahwa Pill box dapat meningkatkan kepatuhan (P=0,000) dan menurunkan tekanan darah sistolik dan diastolik secara signifikan (P=0,000 dan P=0,002), sedangkan pada Medication reminder chart hanya efektif dalam meningkatkan kepatuhan (P=0,000). Terdapat perbedaan yang signifikan antara Pill box dan Medication reminder chart dalam meningkatkan kepatuhan (P=0,008) dan pada penurunan tekanan darah sistolik dan diastolik (P=0,006 dan P= 0,016).
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Saha, Saibal Kumar, Anindita Adhikary, Ajeya Jha, and Vijay Kumar Mehta. "Improvement in Medication Adherence Using TV Programmes as Reminders." International Journal of Asian Business and Information Management 12, no. 3 (July 2021): 242–54. http://dx.doi.org/10.4018/ijabim.20210701.oa15.

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According to WHO, only 50% of patients adhere to chronic therapy. The problem of non-adherence has persisted over decades. Over 197 million Indian households have TV sets, and on average Indians spend 3 hours, 44 minutes watching television. A TV programme is used as intervention by patients to improve medication adherence rates. The objective of the research is to find the effect of TV programmes as a form of reminder in improving medication adherence. With the help of a structured questionnaire, the information about medication adherence behaviour was obtained from patients suffering from different types of diseases in the state of Sikkim, India. It has been found that when patients use TV programmes as a form of reminder, the odds of missing the medication consciously reduces by 45.9%. At a personal level, the probability that a person will not miss the time of medication is 42.3% higher compared to when it is not used, and if the total population is considered, 15.6% fewer people would not be missing the medication at all when the reminder is used.
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Ridho, Abdurahman, Sofa D. Alfian, Job F. M. van Boven, Jutti Levita, Esin Aki Yalcin, Ly Le, Jan-Willem Alffenaar, Eelko Hak, Rizky Abdulah, and Ivan S. Pradipta. "Digital Health Technologies to Improve Medication Adherence and Treatment Outcomes in Patients With Tuberculosis: Systematic Review of Randomized Controlled Trials." Journal of Medical Internet Research 24, no. 2 (February 23, 2022): e33062. http://dx.doi.org/10.2196/33062.

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Background Nonadherence to medication in tuberculosis (TB) hampers optimal treatment outcomes. Digital health technology (DHT) seems to be a promising approach to managing problems of nonadherence to medication and improving treatment outcomes. Objective This paper systematically reviews the effect of DHT in improving medication adherence and treatment outcomes in patients with TB. Methods A literature search in PubMed and Cochrane databases was conducted. Randomized controlled trials (RCTs) that analyzed the effect of DHT interventions on medication adherence outcomes (treatment completion, treatment adherence, missed doses, and noncompleted rate) and treatment outcomes (cure rate and smear conversion) were included. Adult patients with either active or latent TB infection were included. The Jadad score was used for evaluating the study quality. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline was followed to report study findings. Results In all, 16 RCTs were selected from 552 studies found, and 6 types of DHT interventions for TB were identified: 3 RCTs examined video directly observed therapy (VDOT), 1 examined video-observed therapy (VOT), 1 examined an ingestible sensor, 1 examined phone call reminders, 2 examined medication monitor boxes, and 8 examined SMS text message reminders. The outcomes used were treatment adherence, including treatment completion, treatment adherence, missed dose, and noncompleted rate, as well as clinical outcomes, including cure rate and smear conversion. In treatment completion, 4 RCTs (VDOT, VOT, ingestible sensor, SMS reminder) found significant effects, with odds ratios and relative risks (RRs) ranging from 1.10 to 7.69. Treatment adherence was increased in 1 study by SMS reminders (RR 1.05; 95% CI 1.04-1.06), and missed dose was reduced in 1 study by a medication monitor box (mean ratio 0.58; 95% CI 0.42-0.79). In contrast, 3 RCTs of VDOT and 3 RCTs of SMS reminders did not find significant effects for treatment completion. Moreover, no improvement was found in treatment adherence in 1 RCT of VDOT, missed dose in 1 RCT of SMS reminder, and noncompleted rate in 1 RCT of a monitor box, and 2 RCTs of SMS reminders. For clinical outcomes such as cure rate, 2 RCTs reported that phone calls (RR 1.30; 95% CI 1.07-1.59) and SMS reminders (OR 2.47; 95% CI 1.13-5.43) significantly affected cure rates. However, 3 RCTs found that SMS reminders did not have a significant impact on cure rate or smear conversion. Conclusions It was found that DHT interventions can be a promising approach. However, the interventions exhibited variable effects regarding effect direction and the extent of improving TB medication adherence and clinical outcomes. Developing DHT interventions with personalized feedback is required to have a consistent and beneficial effect on medication adherence and outcomes among patients with TB.
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Raban, Magdalena Z., Melissa T. Baysari, Mikaela L. Jorgensen, Amina Tariq, Andrew Georgiou, and Johanna I. Westbrook. "Unmet Needs for Transdermal Patch Management in Electronic Medication Administration Records: An Analysis of Data from 66 Aged Care Facilities." Applied Clinical Informatics 11, no. 05 (October 2020): 812–20. http://dx.doi.org/10.1055/s-0040-1721011.

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Abstract Background Transdermal medication patches have caused serious adverse events in residential aged care facilities (RACFs). Preliminary research suggests that facilities are using a workaround consisting of manually entered reminders in their electronic medication administration records (eMARs) to prompt staff to check and remove patches, because the eMAR does not support these tasks. However, the prevalence and factors associated with use of this workaround among facilities is unknown. Objectives The objectives of this study were to (1) examine the frequency and consistency with which manual reminders to check and remove transdermal patches were used in facility eMARs, and (2) identify resident and facility factors associated with reminder use, to inform eMAR redesign. Methods This was a retrospective cross-sectional analysis of eMAR data from 66 Australian RACFs including 4,787 permanent residents, aged ≥65 years in January 2017. Prevalence of the use of reminders to check and remove patches, and consistency in their application within facilities were examined. Generalized estimating equations were used to determine factors associated with use of manual reminders. Results One in five (n = 937) residents used a patch, and 83.6% of patches contained opioids, a high-risk medicine. 56.9% of facilities implemented manually entered check patch reminders in the eMAR, and 72.3% implemented remove reminders. The reminders were applied inconsistently, with only half of these facilities having reminders for all residents with patches. Residents in facilities in regional areas were more likely to have a check reminder compared with those in major cities (adjusted odds ratio = 4.72 [95% confidence interval: 1.69–13.20]). Conclusion Transdermal patches containing high-risk medicines are frequently used in RACFs, but their safe administration is not supported by a widely implemented eMAR. The frequent, but inconsistent use of a workaround to manually enter reminders indicates an unmet need for new eMAR functionality to improve safety.
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Fontanet, Constance P., Niteesh K. Choudhry, Wendy Wood, Ted Robertson, Nancy Haff, Rebecca Oran, Ellen S. Sears, et al. "Randomised controlled trial targeting habit formation to improve medication adherence to daily oral medications in patients with gout." BMJ Open 11, no. 11 (November 2021): e055930. http://dx.doi.org/10.1136/bmjopen-2021-055930.

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IntroductionMedication adherence for patients with chronic conditions such as gout, a debilitating form of arthritis that requires daily medication to prevent flares, is a costly problem. Existing interventions to improve medication adherence have only been moderately effective. Habit formation theory is a promising strategy to improve adherence. The cue-reward-repetition principle posits that habits are formed by repeatedly completing an activity after the same cue and having the action rewarded every time. Over time, cues become increasingly important whereas rewards become less salient because the action becomes automatic. Leveraging the cue-reward-repetition principle could improve adherence to daily gout medications.Methods and analysisThis three-arm parallel randomised controlled trial tests an adaptive intervention that leverages the repetition cue-reward principle. The trial will began recruitment in August 2021 in Boston, Massachusetts, USA. Eligible patients are adults with gout who have been prescribed a daily oral medication for gout and whose most recent uric acid is above 6 mg/dL. Participants will be randomised to one of three arms and given electronic pill bottles. In the two intervention arms, participants will select a daily activity to link to their medication-taking (cue) and a charity to which money will be donated every time they take their medication (reward). Participants in Arm 1 will receive reminder texts about their cue and their charity reward amount will be US$0.50 per day of medication taken. Arm 2 will be adaptive; participants will receive a US$0.25 per adherent-day and no reminder texts. If their adherence is <75% 6 weeks postrandomisation, their reward will increase to US$0.50 per adherent-day and they will receive reminder texts. The primary outcome is adherence to gout medications over 18 weeks.Ethics and disseminationThis trial has ethical approval in the USA. Results will be published in a publicly accessible peer-reviewed journal.Trial registration numberNCT04776161
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Mohammed, Shama, Osman Siddiqi, Owais Ali, Ali Habib, Faraz Haqqi, Maimoona Kausar, and Aamir J. Khan. "User engagement with and attitudes towards an interactive SMS reminder system for patients with tuberculosis." Journal of Telemedicine and Telecare 18, no. 7 (October 2012): 404–8. http://dx.doi.org/10.1258/jtt.2012.120311.

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We conducted a qualitative study to understand user perceptions, acceptability and engagement with an interactive SMS reminder system designed to improve treatment adherence for patients with tuberculosis (TB). Patients received daily reminders and were asked to respond after taking their medication. Non-responsive patients were sent up to three reminders a day. We enrolled 30 patients with TB who had access to a mobile phone and observed their engagement with the system for a one-month period. We also conducted semi-structured interviews with 24 patients to understand their experience with the system. Most patients found the reminders helpful and encouraging. The average response rate over the study period was 57%. However, it fell from a mean response rate of 62% during the first ten days to 49% during the last ten days. Response rates were higher amongst females, participants with some schooling, and participants who had sent an SMS message the week prior to enrolment. Non-responsiveness was associated with a lack of access to the owner of the mobile phone, problems with the mobile phone itself and literacy. Our pilot study suggests that interactive SMS reminders are an acceptable and appreciated method of supporting patients with TB in taking their medication.
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Blocker, Kenneth A., Kathleen C. Insel, Jeannie K. Lee, Qiong Nie, Abidemi Ajuwon, and Wendy A. Rogers. "User Insights for Design of an Antihypertensive Medication Management Application." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 62, no. 1 (September 2018): 1077–81. http://dx.doi.org/10.1177/1541931218621247.

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Hypertension is the most common chronic disease affecting older adults (65+) in the United States. Unfortunately, many struggle to adhere to their antihypertensive medications as only about half diagnosed with the disease have it controlled. Therefore, there is a need for designing supportive medication management systems to aid this population with their antihypertensive medications, especially using increasingly adopted technologies such as smartphones. The preferences of older adults with hypertension must be considered when designing such systems for this population. Six older adults participated in structured interviews to inform the design of the Medication Education, Decision Support, Reminding and Monitoring System (MEDSReM). Results revealed management needs, design insights, and reminder preferences, as well as mostly positive opinions regarding technology use for medication management. These findings informed the development of MEDSReM with the goal of supporting older adults in successfully managing their antihypertensive medications.
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Costa, Filipa Alves, José Pedro Guerreiro, Magda Nunes Melo, Ana da Costa Miranda, Ana Paula Martins, José Garçāo, and Brenda Madureira. "Effect of reminder cards on compliance with antihypertensive medication." International Journal of Pharmacy Practice 13, no. 3 (September 2005): 205–11. http://dx.doi.org/10.1211/ijpp.13.3.0006.

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Gashu, Kassahun Dessie, Kassahun Alemu Gelaye, Richard Lester, and Binyam Tilahun. "Effect of a phone reminder system on patient-centered tuberculosis treatment adherence among adults in Northwest Ethiopia: a randomised controlled trial." BMJ Health & Care Informatics 28, no. 1 (June 2021): e100268. http://dx.doi.org/10.1136/bmjhci-2020-100268.

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ObjectivesThis study aimed to evaluate the effect of the phone reminder system on patient-centred TB treatment adherence during continuation phase, where patients are responsible for taking medication at home.MethodsWe conducted a two-arm randomised controlled trial on adult patients with TB during the continuation phase. In the intervention arm, patients received routine care plus phone-based weekly pill refilling and daily medication reminders. In the control arm, participants received only routine care. A covariate adaptive randomisation technique was used to balance covariates during allocation. The primary outcome was adherence to patient-centred TB treatment, and secondary outcomes included provider–patient relationship and treatment outcomes. We applied per-protocol and intention-to-treat analysis techniques.ResultsWe randomised 306 patients to intervention (n=152) and control (n=154) groups. Adherence to patient-centred TB treatment was 79% (110/139) in intervention and 66.4% (95/143) in control groups, with relative risk (RR) (95% lower CI) (RR=1.632 (1.162 to ∞); p=0.018, one tailed). Good provider–patient relationship was 73.3% (102/139) in intervention group and 52.4% (75/143) in control group, p=0.0001. TB treatment success was 89.5% (136/152) in intervention group and 85.1% (131/154) in control group, p=0.1238.ConclusionsMobile phone-based weekly refilling with daily medication reminder system improved adherence to patient-centred TB treatment and provider–patient relationship; however, there was no significant effect on treatment success.Trial registration numberPan African Clinical Trials Registry (PACTR201901552202539).
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Santo, Karla, Anna Singleton, Kris Rogers, Aravinda Thiagalingam, John Chalmers, Clara K. Chow, and Julie Redfern. "Medication reminder applications to improve adherence in coronary heart disease: a randomised clinical trial." Heart 105, no. 4 (August 27, 2018): 323–29. http://dx.doi.org/10.1136/heartjnl-2018-313479.

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ObjectiveThe aim of the MEDication reminder APPs to improve medication adherence in Coronary Heart Disease Study was to evaluate the effectiveness and feasibility of using publicly available high-quality medication reminder applications (apps) to improve medication adherence compared with usual care in patients with coronary heart disease (CHD). An additional aim was to examine whether an app with additional features improved adherence further.MethodsPatients with CHD (n=163) were randomised to one of three groups: (1) usual care, (2) a basic app or (3) an advanced app with interactive/customisable features. The primary analysis compared usual care versus app use on the primary outcome of the 8-item Morisky Medication Adherence Scale (MMAS-8) at 3 months. Secondary outcomes included blood pressure and cholesterol levels.ResultsThe mean age was 57.9 years and 87.7% were male. At 3 months, patients using an app had higher adherence (mean MMAS-8 score 7.11) compared with the usual care group (mean MMAS-8 score 6.63) with a mean difference between groups of 0.47 (95% CI 0.12 to 0.82, p=0.008). There was no significant difference in patients using the basic app versus the advanced app (mean difference −0.16, 95% CI −0.56 to 0.24, p=0.428). There were no significant differences in secondary clinical outcome measures.ConclusionPatients with CHD who used medication reminder apps had better medication adherence compared with usual care, and using apps with additional features did not improve this outcome further. These data suggest medication apps are likely to help patients with chronic health conditions adhere to medicines, but further examination of whether such benefits are sustained is warranted.Clinical trial registration numberACTRN12616000661471; Results.
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Kheder, Ed, Lijo Saji, Ali Zalpour, Samuel Swanson, and Sreedhar Mandayam. "Improving admission medication reconciliation at a tertiary cancer center." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e18686-e18686. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e18686.

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e18686 Background: Accurate medication reconciliation (MedRec) is a pivotal step ensuring patient safety during transition of care, yet one of the most challenging aspects in healthcare quality and safety. Inaccurate MedRec leads to 40 % of medications errors, 20% of which results in harm. Our aim is to increase rate of accurate MedRec completion at MD Anderson Cancer Center (MDACC), within 24 hours of admission, from 85% to >95% through Best Possible Medication History (BPMH) Methods: During pre-intervention phase, we audited medication review and reconciliation of 50 randomly selected patients within 24 hours from admission to MDACC. Our intervention included: conducting several brain-storming sessions with nursing staff, providers, pharmacists; creating fish bone diagram and process maps; designing educational presentations for nursing staff on how to practice BPMH; educating providers on how to complete medication reconciliation within 24 hours of admissions; assigning nursing champions; and sending email reminders to provider on a daily basis. We audited another 50 patients post intervention. In our project, BPMH accuracy was measured by percentage of patients with zero discrepancies (incorrect dosage, frequency or route; extra medication; discontinued medication not removed from list). Significance was tested for BPMH completion, and MedRec completion using a Binomial Test, while significance for number of discrepancies and audit completion time was tested using a Two Sample t-Test. Results: We collected data on 50 patients pre and 50 post intervention. Our results indicate statistically significant improvement in MedRec rate (100%), reduction of number of discrepancies and audit completion time. Conclusions: Medication review and reconciliation are multi-phased processes. Nurses, Pharmacists and medical providers are the cornerstone of accurate and complete MedRec. Reminder emails to medical providers played a key role in MedRec rate improvement. Additional root cause analysis is needed to further address the medication review completion process in our institution.[Table: see text]
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Stagg, P., and T. Grice. "Nasogastric Medication for Perioperative Parkinson's Rigidity during Anaesthesia Emergence." Anaesthesia and Intensive Care 39, no. 6 (November 2011): 1128–30. http://dx.doi.org/10.1177/0310057x1103900623.

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We present a case of severe rigidity during emergence from general anaesthesia in a 64-year-old man who had suffered from Parkinson's disease for nine years. Controversy still exists over how to optimally manage these patients perioperatively. We successfully managed his Parkinsonism with administration of crushed Sinemet® and amantadine via a nasogastric tube. This case report serves as a reminder of the importance that patients receive their anti-Parkinsonian medications perioperatively, and highlights the potential benefits of inserting a gastric tube to continue anti-Parkinson's medication dosing during prolonged surgery.
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M Ngowi, Kennedy, Eusebious Maro, Rob E Aarnoutse, Blandina T Mmbaga, Mirjam A. G Sprangers, Peter Reiss, Pythia T Nieuwkerk, and Marion Sumari-de Boer. "Feasibility of SMS to remind pregnant and breastfeeding women living with HIV to take antiretroviral treatment in Kilimanjaro region, Tanzania: a pilot study." East African Health Research Journal 4, no. 2 (November 26, 2020): 140–48. http://dx.doi.org/10.24248/eahrj.v4i2.637.

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Background: Pregnant and breastfeeding Women Living with HIV (WLHIV) often have difficulties in reaching adequate levels of adherence (>95%) to Antiretroviral treatment. “Forgetting” is the most commonly mentioned reason. Sending reminders via SMS is expected to improve adherence. We conducted a pilot study to investigate acceptability, user experience and technical feasibility of sending reminder-SMS to WLHIV. Methods: This was a 6-months observational pilot-study among WLHIV attending antenatal and postnatal care at Kilimanjaro Christian Medical Centre in Moshi, Tanzania. Women received a reminder-SMS 30 minutes before usual time of intake. One hour later, they received an SMS asking whether they took medication to which they could reply with ‘Yes’ or ‘No’. Messages were sent 3 times a week on randomly chosen days to prevent reliance on daily messages. We calculated the percentage of number of SMS delivered, failed to be delivered, and replied to. We analysed feedback from exit-interviews about experience with the SMS-reminders. Results: 25 women were enrolled (age 18-45), 2 were lost to follow up. 5,054 messages were sent of which 53 failed to be delivered (1%). 1,880 SMS were sent with a question if medication was taken; 1,012 (54%) messages were replied to, of which 1,003 (99%) were replied with ‘YES’ and closely to ‘YES’, and a total of 9 (1%) with ‘NO’ and ‘closely to NO’. 868 messages (46%) were not responded to due to either dropout, change of phone number, loss of phone or network failure. Results from 18 interviews showed that 16 (89%) women were satisfied with SMS reminders. 2 (11%) were concerned about unwanted disclosure because of the content ‘don’t forget to take medication’ and one reported other privacy issues (6%). 3 (17%) women experienced stigma. Conclusion: 99%of SMS being delivered indicates that SMS reminders in this resource-limited setting are technically feasible. However, concerns regarding privacy were noted, specifically the risk of unwanted disclosure and the experience of stigma. Participants indicated that being made aware of their adherence, motivated them to adhere better. However, personalised and more neutral content of the SMS might be a way to improving the intervention.
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Kailajärvi, Marita, Timo Takala, Paula Grönroos, Nils Tryding, Jorma Viikari, Kerttu Irjala, and Jari Forsström. "Reminders of Drug Effects on Laboratory Test Results." Clinical Chemistry 46, no. 9 (September 1, 2000): 1395–400. http://dx.doi.org/10.1093/clinchem/46.9.1395.

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Abstract Drug effects on laboratory test results are difficult to take into account without an online decision support system. In this study, drug effects on hormone test results were coded using a drug-laboratory effect (DLE) code. The criteria that trigger the reminders were defined. To issue reminders, it was necessary to write a computer program linking the DLE knowledge base with databases containing individual patient medication and laboratory test results. During the first 10 months, 11% of the results from hormone samples were accompanied by one or more DLE reminders. The most common drugs to trigger reminders were glucocorticoids, furosemide, and metoclopramide. Physicians facing the reminders completed a questionnaire on the usefulness of the reminders. All respondents considered them useful. In addition, DLE reminders had caused 74% of respondents to refrain from additional, usually performed examinations. In conclusion, drug effects on laboratory tests should always be considered when interpreting laboratory results. An online reminder system is useful in displaying potential drug effects alongside test results.
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Chapman-Goetz, Jessica, Nerida Packham, Genevieve Gabb, Cassandra Potts, Kitty Yu, Adaire Prosser, Elizabeth Hotham, and Vijayaprakash Suppiah. "Acceptability and feasibility of the NPS MedicineWise mobile phone application in supporting medication adherence in patients with chronic heart failure: Protocol for a pilot study." PLOS ONE 17, no. 2 (February 4, 2022): e0263284. http://dx.doi.org/10.1371/journal.pone.0263284.

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Introduction Heart failure (HF) is an increasing global concern. Despite evidence-based pharmacotherapy, morbidity and mortality remain high in HF. Medication non-adherence is a crucial factor in optimising clinical outcomes. A growing number of smartphone applications (apps) assist management. While evidence support their use to promote treatment adherence, apps alone may not be the solution. The objective of this pilot study is to assess the acceptability and feasibility of a tiered intervention added to the NPS MedicineWise dose reminder app (MedicineWise app) in supporting medication adherence in HF. Methods and analysis This prospective, single-blinded, randomised controlled trial will recruit 55 Australian patients with HF to be randomly assigned to either intervention (MedicineWise app + usual care) or control (usual care alone) arm. Control participants will remain unaware of the intervention throughout the study. At baseline, intervention participants will be instructed in the MedicineWise app. A reminder will then prompt medication administration at each dosing interval. If non-adherence is suggested from 24 hourly reports (critical medications) or 72 hours (non-critical medications), the individual/s will be escalated through a tiered, pharmacist-led intervention. The primary outcome will be the acceptability and feasibility of this approach in supporting adherence. Between-group comparison of the Self-Efficacy for Appropriate Medication Use Scale (SEAMS) at baseline, 3 and 6 months will be used to measure the app’s value in supporting adherence. Secondary outcome measures include self-reported medication adherence and knowledge, health-related quality of life, psychological wellbeing, signs and symptoms of HF, and medication and HF knowledge. Ethics and dissemination The protocol received ethics approval from Central Adelaide Clinical Human Research Ethics Committee (Protocol number R20190302) and University of South Australia Human Research Ethics Committee (Protocol number 202450). Findings will be disseminated through peer-reviewed journals. Trial registration number Australian New Zealand Clinical Trials Registry Clinical trial number: ACTRN12619000289112p (http://www.ANZCTR.org.au/ACTRN12619000289112p.aspx)
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Ni, Zhao, Latefa Dardas, Bei Wu, and Ryan Shaw. "Cardioprotective medication adherence among patients with coronary heart disease in China: a systematic review." Heart Asia 11, no. 2 (June 2019): e011173. http://dx.doi.org/10.1136/heartasia-2018-011173.

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In China, poor cardioprotective medication adherence is a key reason for the high mortality rate of coronary heart disease (CHD). The aims of this systematic review are to (1) describe and synthesise factors that influence medication adherence among Chinese people with CHD, (2) evaluate the current status of intervention studies, and (3) discuss directions of future research to improve medication adherence. A comprehensive search using PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase, Scopus, Global Health and PsycINFO was undertaken to describe poor adherence in China. Thirty-three eligible articles were included in the study. The review shows that there are multiple contributing factors to poor medication adherence, including patients’ sociodemographic characteristics, health status and medication characteristics. In addition, from patients’ perspective, lack of medication-related knowledge, such as the name, function, dosage and frequency, contributes to poor adherence. From physicians’ perspective, a gap exists between CHD secondary prevention guidelines and clinical practice in China. Follow-up phone calls, educational lectures, booklets and reminder cards were common methods found to be effective in improving medication adherence. This systematic review indicates that cardioprotective medications were commonly prescribed as secondary prevention medication to patients with CHD in China, but adherence to these medications gradually decreased during a follow-up period. Therefore, more research should be conducted on how to establish high-quality health educational programmes aimed at increasing patients’ medication adherence.
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Tran, Nancy, Janet M. Coffman, Kaharu Sumino, and Michael D. Cabana. "Patient reminder systems and asthma medication adherence: a systematic review." Journal of Asthma 51, no. 5 (February 13, 2014): 536–43. http://dx.doi.org/10.3109/02770903.2014.888572.

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Uchimura, Y., K. Omae, K. Waki, H. Fujita, K. Ohe, and M. Hayakawa. "A Smartphone-based Medication Self-management System with Real-time Medication Monitoring." Applied Clinical Informatics 04, no. 01 (2013): 37–52. http://dx.doi.org/10.4338/aci-2012-10-ra-0045.

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SummaryBackground: Most patients cannot remember their entire medication regimen and occasionally forget to take their medication.Objectives: The objective of the study was to design, develop, and demonstrate the feasibility of a new type of medication self-management system using smartphones with real-time medication monitoring.Methods: We designed and developed a smartphone-based medication self-management system (SMSS) based on interviews of 116 patients. The system offered patients two main functions by means of smartphones: (1) storage and provision of an accurate, portable medication history and medication-taking records of patients; and (2) provision of a reminder to take medication only when the patient has forgotten to take his/her medication. These functions were realized by two data input methods: (a) reading of prescription data represented in two-dimensional barcodes using the smartphone camera and getting the photographic images of the pills; and (b) real-time medication monitoring by novel user-friendly wireless pillboxes.Results: Interviews suggested that a pocket-sized pillbox was demanded to support patient’s medication-taking outside the home and pillboxes for home use should be adaptable to the different means of pillbox storage. In accordance with the result, we designed and developed SMSS. Ten patients participated in the feasibility study. In 17 out of 47 cases (36.2%), patients took their medication upon being presented with reminders by the system. Correct medication-taking occur-rence was improved using this system.Conclusions: The SMSS is acceptable to patients and has the advantage of supporting ubiquitous medication self-management using a smartphone. We believe that the proposed system is feasible and provides an innovative solution to encourage medication self-management.Citation: Hayakawa M, Uchimura Y, Omae K, Waki K, Fujita H, Ohe K. A smartphone-based medication selfmanagement system with real-time medication monitoring. Appl Clin Inf 2013; 4: 37–52http://dx.doi.org/10.4338/ACI-2012-10-RA-0045
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Johnson, Kevin B., Barron L. Patterson, Yun-Xian Ho, Qingxia Chen, Hui Nian, Coda L. Davison, Jason Slagle, and Shelagh A. Mulvaney. "The feasibility of text reminders to improve medication adherence in adolescents with asthma." Journal of the American Medical Informatics Association 23, no. 3 (December 11, 2015): 449–55. http://dx.doi.org/10.1093/jamia/ocv158.

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Objective Personal health applications have the potential to help patients with chronic disease by improving medication adherence, self-efficacy, and quality of life. The goal of this study was to assess the impact of MyMediHealth (MMH) – a website and a short messaging service (SMS)-based reminder system – on medication adherence and perceived self-efficacy in adolescents with asthma. Methods We conducted a block-randomized controlled study in academic pediatric outpatient settings. There were 98 adolescents enrolled. Subjects who were randomized to use MMH were asked to create a medication schedule and receive SMS reminders at designated medication administration times for 3 weeks. Control subjects received action lists as a part of their usual care. Primary outcome measures included MMH usage patterns and self-reports of system usability, medication adherence, asthma control, self-efficacy, and quality of life. Results Eighty-nine subjects completed the study, of whom 46 were randomized to the intervention arm. Compared to controls, we found improvements in self-reported medication adherence (P = .011), quality of life (P = .037), and self-efficacy (P = .016). Subjects reported high satisfaction with MMH; however, the level of system usage varied widely, with lower use among African American patients. Conclusions MMH was associated with improved medication adherence, perceived quality of life, and self-efficacy. Trial Registration This project was registered under http://clinicaltrials.gov/ identifier NCT01730235.
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McBride, Ciara M., Eimear C. Morrissey, and Gerard J. Molloy. "Patients’ Experiences of Using Smartphone Apps to Support Self-Management and Improve Medication Adherence in Hypertension: Qualitative Study." JMIR mHealth and uHealth 8, no. 10 (October 28, 2020): e17470. http://dx.doi.org/10.2196/17470.

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Background Worldwide, hypertension control rates remain suboptimal despite clinically effective antihypertensive drug therapy. Patient failure to take medication as prescribed (ie, nonadherence) is the most important factor contributing to poor control. Smartphone apps can facilitate the delivery of evidence-based behavior change techniques to improve adherence and may provide a scalable, usable, and feasible method to deliver self-management support. Objective The aim of this study is to explore patients’ experiences of the usability and feasibility of smartphone apps to support self-management and improve medication adherence in hypertension. Methods A qualitative descriptive study was conducted. A total of 11 people living with hypertension from the West of Ireland were sampled purposively and interviewed about their experience of using a self-management app for a 4-week period, which included two key functionalities: self-monitoring of blood pressure (BP) and medication reminders. Thematic analysis was carried out on the semistructured interview data. Results Participants’ age ranged from 43 to 74 years (mean 62 years, SD 9.13). Three themes were identified: digital empowerment of self-management, human versus digital systems, and digital sustainability. Although patients’ experience of using the technology to self-monitor BP was one of empowerment, characterized by an enhanced insight and understanding into their condition, control, and personal responsibility, the reminder function was only feasible for patients who reported unintentional nonadherence to treatment. Patients experienced the app as a sustainable tool to support self-management and found it easy to use, including those with limited technological competence. Conclusions The study’s findings provide new insights into the experience of using apps to support medication adherence in hypertension. Overall, the data support apps as a usable and feasible method to aid self-management of hypertension and highlight the need for personalized functionality, particularly with regard to medication adherence reminder strategies. The study’s findings challenge the perspective that the use of these technologies to support self-management can inevitably add to the burden of treatment experienced by patients.
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Hendra, Godeliva Adriani. "PENGARUH PMR DENGAN KARTU PENGINGAT TERHADAP KEPATUHAN DAN KESESUAIAN PENGOBATAN PASIEN TUBERKULOSIS." Journal of Pharmaceutical Care Anwar Medika 3, no. 1 (December 30, 2020): 22–30. http://dx.doi.org/10.36932/jpcam.v3i1.42.

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The duration of tuberculosis treatment affects patient adherence. The pharmacist monitors the patient's medication by providing an intervention in the form of a reminder card. The research objective was to use a reminder card to determine the compliance level of tuberculosis patients. The design of this study was a pre-experimental one group pretest-post test from December 2019 - January 2020. The study sample was 133 adult tuberculosis patients who received detached drugs and had undergone treatment >1 month at the Pulmonary Poly Outpatient Waluyo Jati Kraksaan Hospital. The level of adherence with the reminder card intervention was calculated using the pill count method and analyzed using the Wilcoxon test. The result of tuberculosis patient adherence level increased significantly (p<0.05) after giving the reminder card from 50.00% to 99.37%. Providing a reminder card is an effort that can improve adherence to treatment of tuberculosis patients.
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Hendra, Godeliva Adriani. "PENGARUH PMR DENGAN KARTU PENGINGAT TERHADAP KEPATUHAN DAN KESESUAIAN PENGOBATAN PASIEN TUBERKULOSIS." Journal of Pharmaceutical Care Anwar Medika 3, no. 1 (December 30, 2020): 22–30. http://dx.doi.org/10.36932/jpcam.v3i1.42.

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The duration of tuberculosis treatment affects patient adherence. The pharmacist monitors the patient's medication by providing an intervention in the form of a reminder card. The research objective was to use a reminder card to determine the compliance level of tuberculosis patients. The design of this study was a pre-experimental one group pretest-post test from December 2019 - January 2020. The study sample was 133 adult tuberculosis patients who received detached drugs and had undergone treatment >1 month at the Pulmonary Poly Outpatient Waluyo Jati Kraksaan Hospital. The level of adherence with the reminder card intervention was calculated using the pill count method and analyzed using the Wilcoxon test. The result of tuberculosis patient adherence level increased significantly (p<0.05) after giving the reminder card from 50.00% to 99.37%. Providing a reminder card is an effort that can improve adherence to treatment of tuberculosis patients.
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Adikusuma, Wirawan, and Nurul Qiyaam. "ADHERENCE LEVEL AND BLOOD SUGAR CONTROL OF TYPE 2 DIABETES MELLITUS PATIENTS WHO GETS COUNSELING AND SHORT MESSAGES SERVICE AS REMINDER AND MOTIVATION." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (February 1, 2018): 219. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.22988.

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Objective: Examines the effects of counseling and short messages service (SMS) as a reminder and motivation toward medication adherence improvement and controlled HbA1c levels of type 2 diabetes mellitus (T2DM) patients.Methods: This study used a quasi-experimental method with prospective data retrieval. The subjects of this study were 40 patients with outpatient T2DM in internal disease polyclinic in West Nusa Tenggara Hospital, Indonesia. Patients who fulfilled the inclusion criteria were divided into two groups: The control group (n=20) receiving only the drug care service and the treatment group (n=20) receiving counseling and SMS reminder and motivation from the pharmacist. Data collecting was conducted using the pill count method, and HbA1c levels were taken from the medical record.Results: The results showed that counseling and SMS as reminder and motivation by a pharmacist can improve treatment adherence significantly (p<0.05) by 11.33 ± 8.47 and can decrease HbA1c level significantly (p<0.05) of 1.32 ± 0.72 in the intervention group. There was a positive correlation between T2DM patient treatment adherence to HbA1c levels (r=0.254, p=0.023).Conclusion: The provision of counseling and SMS as a reminder and motivation by the pharmacist can have a positive effect toward medication adherence and control of HbA1c in T2DM patients.
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Patel, Samir, Laura Jacobus-Kantor, Lorraine Marshall, Clark Ritchie, Michelle Kaplinski, Parvinder S. Khurana, and Richard J. Katz. "Mobilizing Your Medications: An Automated Medication Reminder Application for Mobile Phones and Hypertension Medication Adherence in a High-Risk Urban Population." Journal of Diabetes Science and Technology 7, no. 3 (May 2013): 630–39. http://dx.doi.org/10.1177/193229681300700307.

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Barik, Ardila Lailatul, Retno Indarwati, and Sulistiawati Sulistiawati. "The Effectiveness Of Using Text Messages Reminder On Adherence With Tuberculosis Patients: A Systematic Review." STRADA Jurnal Ilmiah Kesehatan 9, no. 2 (November 1, 2020): 751–60. http://dx.doi.org/10.30994/sjik.v9i2.381.

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Non-adherence is a factor that inhibits the completion of TB cases globally. Some studies suggest that the use of digital technology in the form of text message reminders can reduce the risk of non-adherence. The purpose of writing this article is to analyze the effectiveness of text message reminders on adherence to tuberculosis (TB) patients. The method in preparing this Systematic review is based on literature studies from various electronic databases, including Scopus, ScienceDirect, ProQuest, and Sage by conducting a comprehensive review using the PRISMA guidelines. The keywords used are "Text Messaging" AND "medication adherence" AND "tuberculosis". There are 11 original articles with 9 articles using the Randomized Control Trials (RCTs) research method and 2 articles using the Quasy-experimental method that fits the inclusion criteria. The use of text message reminder interventions is effective and can be used as an optional method of increasing adherence to TB patients.
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Aisyah Rahimi, Hamimi Zakri, and Azira Khalil. "Development of Automatic Reminder System for Geriatric Medicine Intake." Malaysian Journal of Science Health & Technology 7, no. 1 (March 30, 2021): 8–14. http://dx.doi.org/10.33102/mjosht.v7i1.152.

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The consumption of medicine is typical in geriatrics, having many problems related to medications. Geriatrics often forget to take their medicine, and this problem can be overcome by using an automatic reminder system. In this study, an automated reminder system is developed as an improved community element, acting as a system that can help geriatric in taking their medicine on time, thus, boosting their health condition. This reminder system also includes an interaction between the geriatrics and their caretakers. This reminder system includes Arduino UNO as the microcontroller, with the notification system, Blynk Application, a buzzer, and a light-emitting diode (LED) system. To make this reminder system more versatile, the buzzer will alarm during the medicine intake time, giving information to the elderly on which medicine to take. When the time has reached to take medication, the buzzer will produce a sound. Suppose the medicine box opens after the buzzer's sound and is detected by the passive infrared sensor (PIR sensor). In that case, the caretaker will receive a notification through the Blynk application that the geriatric already took medicine. On the contrary, if the medicine box is not open after 3 minutes following the buzzer's sound, which indicates that the geriatric did not take their medicine, the system will not send a notification to their caretakers on the status. This prototype is tested on ten users for its accuracy and effectiveness. It is believed that this system can provide geriatrics more alert in taking their medicine on time, enhancing their health status.
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Shade, Marcia, Kyle Rector, Rasila Soumana, and Kevin Kupzyk. "You Have One Reminder: Self-Manage Your Pain." Innovation in Aging 4, Supplement_1 (December 1, 2020): 205. http://dx.doi.org/10.1093/geroni/igaa057.664.

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Abstract Pain has a significant impact in the lives of aging adults. As the population of America grows older, they need to be encouraged to use pain self-management strategies. Technology is an option, but current pain management applications have usability limitations in older adults. This feasibility study describes the usability of voice assistant reminders for pain self-management. We enrolled 15 community-dwelling aging adults with chronic pain. Participants created two pre-determined voice assistant reminder tasks: 1) to take scheduled pain medication, and 2) to write in a pain diary. We collected data on demographics, pain, confidence of managing symptoms, and objective ease of use. After four weeks, we collected information about subjective ease of use and usefulness of the voice assistant. Participants were mostly female, average age 65 years; reporting moderate pain severity 4.58 (SD 2.29) and pain interference 3.94 (SD 2.62). The mean PROMIS self-efficacy for managing symptoms score was 50.8 (SD 8.2). Voice assistant usability was above average (78 out of 100). The median time to make a voice assistant profile was five minutes (SD 7.5), with a median of seeking help two times. No significant relationships were found between pain and usability. Three participants made physical activity and distraction reminders to self-manage pain. Voice assistant reminders were perceived as consistent, easy to set up and helpful for accountability. Older users may provide helpful feedback for development and testing of voice assistant software for pain self-management. Voice assistants may provide helpful reminders that encourage the completion of pain self-management strategies.
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