Academic literature on the topic 'Medical records Australia Data processing'

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Journal articles on the topic "Medical records Australia Data processing"

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Pearce, Christopher, Adam McLeod, Jon Patrick, Jason Ferrigi, Michael Michael Bainbridge, Natalie Rinehart, and Anna Fragkoudi. "Coding and classifying GP data: the POLAR project." BMJ Health & Care Informatics 26, no. 1 (November 2019): e100009. http://dx.doi.org/10.1136/bmjhci-2019-100009.

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BackgroundData, particularly ‘big’ data are increasingly being used for research in health. Using data from electronic medical records optimally requires coded data, but not all systems produce coded data.ObjectiveTo design a suitable, accurate method for converting large volumes of narrative diagnoses from Australian general practice records to codify them into SNOMED-CT-AU. Such codification will make them clinically useful for aggregation for population health and research purposes.MethodThe developed method consisted of using natural language processing to automatically code the texts, followed by a manual process to correct codes and subsequent natural language processing re-computation. These steps were repeated for four iterations until 95% of the records were coded. The coded data were then aggregated into classes considered to be useful for population health analytics.ResultsCoding the data effectively covered 95% of the corpus. Problems with the use of SNOMED CT-AU were identified and protocols for creating consistent coding were created. These protocols can be used to guide further development of SNOMED CT-AU (SCT). The coded values will be immensely useful for the development of population health analytics for Australia, and the lessons learnt applicable elsewhere.
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Joshi, Ranee, Kavitha Madaiah, Mark Jessell, Mark Lindsay, and Guillaume Pirot. "<i>dh2loop</i> 1.0: an open-source Python library for automated processing and classification of geological logs." Geoscientific Model Development 14, no. 11 (November 4, 2021): 6711–40. http://dx.doi.org/10.5194/gmd-14-6711-2021.

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Abstract. A huge amount of legacy drilling data is available in geological survey but cannot be used directly as they are compiled and recorded in an unstructured textual form and using different formats depending on the database structure, company, logging geologist, investigation method, investigated materials and/or drilling campaign. They are subjective and plagued by uncertainty as they are likely to have been conducted by tens to hundreds of geologists, all of whom would have their own personal biases. dh2loop (https://github.com/Loop3D/dh2loop, last access: 30 September 2021​​​​​​​) is an open-source Python library for extracting and standardizing geologic drill hole data and exporting them into readily importable interval tables (collar, survey, lithology). In this contribution, we extract, process and classify lithological logs from the Geological Survey of Western Australia (GSWA) Mineral Exploration Reports (WAMEX) database in the Yalgoo–Singleton greenstone belt (YSGB) region. The contribution also addresses the subjective nature and variability of the nomenclature of lithological descriptions within and across different drilling campaigns by using thesauri and fuzzy string matching. For this study case, 86 % of the extracted lithology data is successfully matched to lithologies in the thesauri. Since this process can be tedious, we attempted to test the string matching with the comments, which resulted in a matching rate of 16 % (7870 successfully matched records out of 47 823 records). The standardized lithological data are then classified into multi-level groupings that can be used to systematically upscale and downscale drill hole data inputs for multiscale 3D geological modelling. dh2loop formats legacy data bridging the gap between utilization and maximization of legacy drill hole data and drill hole analysis functionalities available in existing Python libraries (lasio, welly, striplog).
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Morrow, Melanie, Hollie Sekulich, Abigail Trewin, and Peter Archer. "Immunization Readiness of a Deploying Emergency Medical Team." Prehospital and Disaster Medicine 34, s1 (May 2019): s137—s138. http://dx.doi.org/10.1017/s1049023x19003030.

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Introduction:It is a requirement for a World Health Organization verified Emergency Medical Team (EMT) that all members be immunized against common diseases in the deploying region. Most jurisdictions use private suppliers such as travel doctors for immunization services. When a deployment is announced, members are nominated by their jurisdiction under the condition they are fully immunized. It is up to the individual to monitor their immunization status.Aim:To determine how many members nominated for deployment were fully immunized.Methods:Nominated members sent their completed vaccination record to a central location for assessment of their immunization status. The following data were recorded: vaccination status, last-minute booster doses required, and the number of emails sent by the assessor in processing the records. The number of phone calls made and received were not recorded.Results:To complete the skills matrix for a field hospital containing an emergency department and operating theater (an EMT type 2), 61 members were nominated. At the time of assessment, 32 (52%) were fully immunized, requiring no further booster doses (vaccinations or serology tests). Three members were removed from the deployment as they were not fully immunized. Last-minute booster doses were required by 27 (44%) members, with a total of 74 booster doses administered (range 0-5). 19 of the booster doses administered were immunizations required to work in any health facility in Australia. The most common vaccines requiring booster doses were rabies (n=21) and typhoid (n=15). 58 emails were sent over a period of 5 days to 24 members to clarify vaccination status.Discussion:This deployment highlighted a gap in members’ perception of their immunization status, leading to delays in deployment readiness for the team. A new electronic system where vaccine status tracking occurs in real time should address this issue.
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Young, Marcus, Natasha Holmes, Raymond Robbins, Nada Marhoon, Sobia Amjad, Ary Serpa Neto, and Rinaldo Bellomo. "Natural language processing to assess the epidemiology of delirium-suggestive behavioural disturbances in critically ill patients." Critical Care and Resuscitation 23, no. 2 (June 7, 2021): 144–53. http://dx.doi.org/10.51893/2021.2.oa1.

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Background: There is no gold standard approach for delirium diagnosis, making the assessment of its epidemiology difficult. Delirium can only be inferred though observation of behavioural disturbance and described with relevant nouns or adjectives. Objective: We aimed to use natural language processing (NLP) and its identification of words descriptive of behavioural disturbance to study the epidemiology of delirium in critically ill patients. Study design: Retrospective study using data collected from the electronic health records of a university-affiliated intensive care unit (ICU) in Melbourne, Australia. Participants: 12 375 patients Intervention: Analysis of electronic progress notes. Identification using NLP of at least one of a list of words describing behavioural disturbance within such notes. Results: We analysed 199 648 progress notes in 12 375 patients. Of these, 5108 patients (41.3%) had NLP-diagnosed behavioural disturbance (NLP-Dx-BD). Compared with those who did not have NLP-Dx-DB, these patients were older, more severely ill, and likely to have medical or unplanned admissions, neurological diagnosis, chronic kidney or liver disease and to receive mechanical ventilation and renal replacement therapy (P < 0.001). The unadjusted hospital mortality for NLP-Dx-BD patients was 14.1% versus 9.6% for patients without NLP-Dx-BD. After adjustment for baseline characteristics and illness severity, NLP-Dx-BD was not associated with increased risk of death (odds ratio [OR], 0.94; 95% CI, 0.80–1.10); a finding robust to multiple sensitivity, subgroups and time of observation subcohort analyses. In mechanically ventilated patients, NLP-Dx-BD was associated with decreased hospital mortality (OR, 0.80; 95% CI, 0.65–0.99) after adjustment for baseline severity of illness and year of admission. Conclusions: NLP enabled rapid assessment of large amounts of data identifying a population of ICU patients with typical high risk characteristics for delirium. Moreover, this technique enabled identification of previously poorly understood associations. Further investigations of this technique appear justified.
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Musa, Ibrahim, Hyun Park, Lkhagvadorj Munkhdalai, and Keun Ryu. "Global Research on Syndromic Surveillance from 1993 to 2017: Bibliometric Analysis and Visualization." Sustainability 10, no. 10 (September 25, 2018): 3414. http://dx.doi.org/10.3390/su10103414.

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Syndromic Surveillance aims at analyzing medical data to detect clusters of illness or forecast disease outbreaks. Although the research in this field is flourishing in terms of publications, an insight of the global research output has been overlooked. This paper aims at analyzing the global scientific output of the research from 1993 to 2017. To this end, the paper uses bibliometric analysis and visualization to achieve its goal. Particularly, a data processing framework was proposed based on citation datasets collected from Scopus and Clarivate Analytics’ Web of Science Core Collection (WoSCC). The bibliometric method and Citespace were used to analyze the institutions, countries, and research areas as well as the current hotspots and trends. The preprocessed dataset includes 14,680 citation records. The analysis uncovered USA, England, Canada, France and Australia as the top five most productive countries publishing about Syndromic Surveillance. On the other hand, at the Pinnacle of academic institutions are the US Centers for Disease Control and Prevention (CDC). The reference co-citation analysis uncovered the common research venues and further analysis of the keyword cooccurrence revealed the most trending topics. The findings of this research will help in enriching the field with a comprehensive view of the status and future trends of the research on Syndromic Surveillance.
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Hallinan, Christine Mary, Sedigheh Khademi Habibabadi, Mike Conway, and Yvonne Ann Bonomo. "Social media discourse and internet search queries on cannabis as a medicine: A systematic scoping review." PLOS ONE 18, no. 1 (January 20, 2023): e0269143. http://dx.doi.org/10.1371/journal.pone.0269143.

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The use of cannabis for medicinal purposes has increased globally over the past decade since patient access to medicinal cannabis has been legislated across jurisdictions in Europe, the United Kingdom, the United States, Canada, and Australia. Yet, evidence relating to the effect of medical cannabis on the management of symptoms for a suite of conditions is only just emerging. Although there is considerable engagement from many stakeholders to add to the evidence base through randomized controlled trials, many gaps in the literature remain. Data from real-world and patient reported sources can provide opportunities to address this evidence deficit. This real-world data can be captured from a variety of sources such as found in routinely collected health care and health services records that include but are not limited to patient generated data from medical, administrative and claims data, patient reported data from surveys, wearable trackers, patient registries, and social media. In this systematic scoping review, we seek to understand the utility of online user generated text into the use of cannabis as a medicine. In this scoping review, we aimed to systematically search published literature to examine the extent, range, and nature of research that utilises user-generated content to examine to cannabis as a medicine. The objective of this methodological review is to synthesise primary research that uses social media discourse and internet search engine queries to answer the following questions: (i) In what way, is online user-generated text used as a data source in the investigation of cannabis as a medicine? (ii) What are the aims, data sources, methods, and research themes of studies using online user-generated text to discuss the medicinal use of cannabis. We conducted a manual search of primary research studies which used online user-generated text as a data source using the MEDLINE, Embase, Web of Science, and Scopus databases in October 2022. Editorials, letters, commentaries, surveys, protocols, and book chapters were excluded from the review. Forty-two studies were included in this review, twenty-two studies used manually labelled data, four studies used existing meta-data (Google trends/geo-location data), two studies used data that was manually coded using crowdsourcing services, and two used automated coding supplied by a social media analytics company, fifteen used computational methods for annotating data. Our review reflects a growing interest in the use of user-generated content for public health surveillance. It also demonstrates the need for the development of a systematic approach for evaluating the quality of social media studies and highlights the utility of automatic processing and computational methods (machine learning technologies) for large social media datasets. This systematic scoping review has shown that user-generated content as a data source for studying cannabis as a medicine provides another means to understand how cannabis is perceived and used in the community. As such, it provides another potential ‘tool’ with which to engage in pharmacovigilance of, not only cannabis as a medicine, but also other novel therapeutics as they enter the market.
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Unwin, Elizabeth, James Codde, Louise Gill, Suzanne Stevens, and Timothy Nelson. "The WA Hospital Morbidity Data System: An Evaluation of its Performance and the Impact of Electronic Data Transfer." Health Information Management 26, no. 4 (December 1996): 189–92. http://dx.doi.org/10.1177/183335839702600407.

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This paper evaluates the performance of the Hospital Morbidity Data System, maintained by the Health Statistics Branch (HSB) of the Health Department of Western Australia (WA). The time taken to process discharge summaries was compared in the first and second halves of 1995, using the number of weeks taken to process 90% of all discharges and the percentage of records processed within four weeks as indicators of throughput. Both the hospitals and the HSB showed improvements in timeliness during the second half of the year. The paper also examines the impact of a recently introduced electronic data transfer system for WA country public hospitals on the timeliness of morbidity data. The processing time of country hospital records by the HSB was reduced to a similar time as for metropolitan hospitals, but the processing time in the hospitals increased, resulting in little improvement in total processing time.
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Mesibov, Robert. "An audit of some processing effects in aggregated occurrence records." ZooKeys 751 (April 20, 2018): 129–46. http://dx.doi.org/10.3897/zookeys.751.24791.

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A total of ca 800,000 occurrence records from the Australian Museum (AM), Museums Victoria (MV) and the New Zealand Arthropod Collection (NZAC) were audited for changes in selected Darwin Core fields after processing by the Atlas of Living Australia (ALA; for AM and MV records) and the Global Biodiversity Information Facility (GBIF; for AM, MV and NZAC records). Formal taxon names in the genus- and species-groups were changed in 13–21% of AM and MV records, depending on dataset and aggregator. There was little agreement between the two aggregators on processed names, with names changed in two to three times as many records by one aggregator alone compared to records with names changed by both aggregators. The type status of specimen records did not change with name changes, resulting in confusion as to the name with which a type was associated. Data losses of up to 100% were found after processing in some fields, apparently due to programming errors. The taxonomic usefulness of occurrence records could be improved if aggregators included both original and the processed taxonomic data items for each record. It is recommended that end-users check original and processed records for data loss and name replacements after processing by aggregators.
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Sun, Wencheng, Zhiping Cai, Yangyang Li, Fang Liu, Shengqun Fang, and Guoyan Wang. "Data Processing and Text Mining Technologies on Electronic Medical Records: A Review." Journal of Healthcare Engineering 2018 (2018): 1–9. http://dx.doi.org/10.1155/2018/4302425.

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Currently, medical institutes generally use EMR to record patient’s condition, including diagnostic information, procedures performed, and treatment results. EMR has been recognized as a valuable resource for large-scale analysis. However, EMR has the characteristics of diversity, incompleteness, redundancy, and privacy, which make it difficult to carry out data mining and analysis directly. Therefore, it is necessary to preprocess the source data in order to improve data quality and improve the data mining results. Different types of data require different processing technologies. Most structured data commonly needs classic preprocessing technologies, including data cleansing, data integration, data transformation, and data reduction. For semistructured or unstructured data, such as medical text, containing more health information, it requires more complex and challenging processing methods. The task of information extraction for medical texts mainly includes NER (named-entity recognition) and RE (relation extraction). This paper focuses on the process of EMR processing and emphatically analyzes the key techniques. In addition, we make an in-depth study on the applications developed based on text mining together with the open challenges and research issues for future work.
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da Rocha, Naila Camila, Abner Macola Pacheco Barbosa, Yaron Oliveira Schnr, Juliana Machado-Rugolo, Luis Gustavo Modelli de Andrade, José Eduardo Corrente, and Liciana Vaz de Arruda Silveira. "Natural Language Processing to Extract Information from Portuguese-Language Medical Records." Data 8, no. 1 (December 29, 2022): 11. http://dx.doi.org/10.3390/data8010011.

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Studies that use medical records are often impeded due to the information presented in narrative fields. However, recent studies have used artificial intelligence to extract and process secondary health data from electronic medical records. The aim of this study was to develop a neural network that uses data from unstructured medical records to capture information regarding symptoms, diagnoses, medications, conditions, exams, and treatment. Data from 30,000 medical records of patients hospitalized in the Clinical Hospital of the Botucatu Medical School (HCFMB), São Paulo, Brazil, were obtained, creating a corpus with 1200 clinical texts. A natural language algorithm for text extraction and convolutional neural networks for pattern recognition were used to evaluate the model with goodness-of-fit indices. The results showed good accuracy, considering the complexity of the model, with an F-score of 63.9% and a precision of 72.7%. The patient condition class reached a precision of 90.3% and the medication class reached 87.5%. The proposed neural network will facilitate the detection of relationships between diseases and symptoms and prevalence and incidence, in addition to detecting the identification of clinical conditions, disease evolution, and the effects of prescribed medications.
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Dissertations / Theses on the topic "Medical records Australia Data processing"

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Forsyth, Rowena Public Health &amp Community Medicine Faculty of Medicine UNSW. "Tricky technology, troubled tribes: a video ethnographic study of the impact of information technology on health care professionals??? practices and relationships." Awarded by:University of New South Wales. School of Public Health and Community Medicine, 2006. http://handle.unsw.edu.au/1959.4/30175.

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Whilst technology use has always been a part of the practice of health care delivery, more recently, information technology has been applied to aspects of clinical work concerned with documentation. This thesis presents an analysis of the ways that two professional groups, one clinical and one ancillary, at a single hospital cooperatively engage in a work practice that has recently been computerised. It investigates the way that a clinical group???s approach to and actual use of the system creates problems for the ancillary group. It understands these problems to arise from the contrasting ways that the groups position their use of documentation technology in their local definitions of professional status. The data on which analysis of these practices is based includes 16 hours of video recordings of the work practices of the two groups as they engage with the technology in their local work settings as well as video recordings of a reflexive viewing session conducted with participants from the ancillary group. Also included in the analysis are observational field notes, interviews and documentary analysis. The analysis aimed to produce a set of themes grounded in the specifics of the data, and drew on TLSTranscription?? software for the management and classification of video data. This thesis seeks to contribute to three research fields: health informatics, sociology of professions and social science research methodology. In terms of health informatics, this thesis argues for the necessity for health care information technology design to understand and incorporate the work practices of all professional groups who will be involved in using the technology system or whose work will be affected by its introduction. In terms of the sociology of professions, this thesis finds doctors and scientists to belong to two distinct occupational communities that each utilise documentation technology to different extents in their displays of professional competence. Thirdly, in terms of social science research methodology, this thesis speculates about the possibility for viewing the engagement of the groups with the research process as indicative of their reactions to future sources of outside perturbance to their work.
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Masiza, Melissa. "Factors affecting the adoption and meaningful use of electronic medical records in general practices." Thesis, Nelson Mandela Metropolitan University, 2012. http://hdl.handle.net/10948/d1018561.

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Patients typically enter the healthcare systems at the primary care level from where they are further referred to specialists or hospitals as necessary. In the private healthcare system, primary care is provided by a general practitioner (GP). A GP will refer a patient to a specialist for treatment when necessary, while the GP remains the main healthcare provider. The provision of care is, thus, fragmented which results in continuity of care becoming a challenge. Furthermore, the majority of healthcare providers continue to use paper-based systems to capture and store patient medical data. However, capturing and storing patient medical data via electronic methods, such as Electronic Medical Records (EMRs), has been found to improve continuity of care. Despite this benefit, research reveals that smaller practices are slow to adopt electronic methods of record keeping. Hence this explorative research attempts to identify factors that affect the lack of adoption and meaningful use of EMRs in general practices. Four general practices are surveyed through patient and staff questionnaires, as well as GP interviews. Socio-Technical Systems (STS) theory is used as a theoretical lens to formulate the resulting factors. The findings of the research indicate specific factors that relate to either the social, environmental or technical sub-systems of the socio-technical system, or an overlap between these sub-systems. It is significant to note that within these sub-systems, the social sub-system plays a key role. This is due to various reasons revealed by this research. Furthermore, multiple perceptions emerged from the GP and patient participants during the analysis of the findings. These perceptions may have an influence on the adoption and potential meaningful use of an EMR in a general practice. Additionally, the socio-technical factors identified from this research highlight the challenges related to encouraging the adoption and meaningful use of EMRs. These challenges are introduced by the complexities represented by these factors. Nevertheless, addressing the factors will contribute towards improving the rate of adoption and meaningful use of EMRs in small practices.
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Vu, Manh Tuan. "Literature review implementation of electronic medical records what factors are driving it? /." Thesis, Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42997896.

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Tse, Pui-yin Fiona, and 謝佩妍. "Systematic review : the return on investment of EHR implementation and associated key factors leading to positive return-on-investment." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193818.

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Background: Implementations of national electronic health record (EHR) were currently underway worldwide as a core objective of eHealth strategies. It was widely believed that implementation of EHR might lead to considerable financial savings. This paper aimed to conduct a systematic review to assess return-on-investment (ROI) of HER implementation and to identify areas with greatest potential to positive ROI for ongoing deliberation on continuous development of EHR. Methodology: An inclusive string was developed to search English paper published between January 2003 and June 2013. This paper only included studies meet the following criteria 1) Primary study; 2) Involve a computerized system with electronic health record; and 3) include some form of economic evaluation. Critical appraisal was undertaken and articles with higher quality were selected. Hard ROI and soft ROI defined for EHR implementation were adopted as outcome metrics to examine both tangible and intangible return of EHR implementation. Results: A total of 18 articles were examined for data extraction and synthesis. Most of the available evidences came from pre-post evaluation or cross-sectional analysis without uniform standards for reporting. Findings of 56% of the articles indicated that there is cost saving after EHR implementation while 17% of the articles indicated loss in totalrevenue. The remaining articles concluded that there is no association between cost reduction and EHR implementation. Among the defined hard ROI, most studies mentioned the positive effect in resource reduction. Some authors argued that the resource was reallocated to other initiatives and resulted in negligible cost saving. According to the selected literatures, evidences showed that EHR was able to achieve defined soft ROI, especially for improving caring process, but the overall outcome was subject to individual practice. Authors of 12 out of 18 articles have identified the factor leading to positive return and provided recommendation toward successful EHR implementation. Other than implying helpful EHR functions and promoting practice change, additional incentive on quality improvement and performance benchmarking should be considered. The organizations and EHR systems studied in the articles examined were vastly different; it would be desirable if a controlled study adopting EHR with uniform standards can be performed to evaluate the ROI of different clinical settings. Conclusions: The benefits of EHR are not guaranteed, it requires change of practice and substantial efforts. Healthcare industries have to equip themselves for implementing the new technology and to exploit the usage for better clinical outcome.
published_or_final_version
Public Health
Master
Master of Public Health
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Herbst, Abraham J. "The use of evaluation in the design and development of interactive medical record systems." Master's thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/27210.

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An explorative study was done to develop an evaluation methodology. This method can be applied during the development of interactive medical record systems in order to provide information which can be used to improve user interaction with the system. Th e evaluation methodology consists of a number of interactive sessions with potential users of the interactive medical record system. During the first two sessions the subjects are trained to use the system. During the third and last session the subjects are videotaped while they are doing a set of benchmark tasks on the system under evaluation. The video recordings are analysed to obtain performance data. This performance data consists of task timings and a list of problems experienced (errors made) by the subjects. The systems evaluated during the study were a problem-oriented manual medical record and an interactive computerized medical record. The computerized record system was specifically developed for this study. The design and subsequent improvements to this system are documented in the study.
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Chava, Nalini. "Administrative reporting for a hospital document scanning system." Virtual Press, 1996. http://liblink.bsu.edu/uhtbin/catkey/1014839.

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This thesis will examine the manual hospital document retrieval system and electronic document scanning system. From this examination, requirements will be listed for the Administrative Reporting for the Hospital Document Scanning System which will provide better service and reliability than the previous systems. To assure that the requirements can be met, this will be developed into a working system which is named as the Administrative Reporting for the Hospital Document Scanning System(ARHDSS).
Department of Computer Science
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Mxoli, Ncedisa Avuya Mercia. "Guidelines for secure cloud-based personal health records." Thesis, Nelson Mandela Metropolitan University, 2017. http://hdl.handle.net/10948/14134.

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Traditionally, health records have been stored in paper folders at the physician’s consulting rooms – or at the patient’s home. Some people stored the health records of their family members, so as to keep a running history of all the medical procedures they went through, and what medications they were given by different physicians at different stages of their lives. Technology has introduced better and safer ways of storing these records, namely, through the use of Personal Health Records (PHRs). With time, different types of PHRs have emerged, i.e. local, remote server-based, and hybrid PHRs. Web-based PHRs fall under the remote server-based PHRs; and recently, a new market in storing PHRs has emerged. Cloud computing has become a trend in storing PHRs in a more accessible and efficient manner. Despite its many benefits, cloud computing has many privacy and security concerns. As a result, the adoption rate of cloud services is not yet very high. A qualitative and exploratory research design approach was followed in this study, in order to reach the objective of proposing guidelines that could assist PHR providers in selecting a secure Cloud Service Provider (CSP) to store their customers’ health data. The research methods that were used include a literature review, systematic literature review, qualitative content analysis, reasoning, argumentation and elite interviews. A systematic literature review and qualitative content analysis were conducted to examine those risks in the cloud environment that could have a negative impact on the secure storing of PHRs. PHRs must satisfy certain dimensions, in order for them to be meaningful for use. While these were highlighted in the research, it also emerged that certain risks affect the PHR dimensions directly, thus threatening the meaningfulness and usability of cloud-based PHRs. The literature review revealed that specific control measures can be adopted to mitigate the identified risks. These control measures form part of the material used in this study to identify the guidelines for secure cloud-based PHRs. The guidelines were formulated through the use of reasoning and argumentation. After the guidelines were formulated, elite interviews were conducted, in order to validate and finalize the main research output: i.e. guidelines. The results of this study may alert PHR providers to the risks that exist in the cloud environment; so that they can make informed decisions when choosing a CSP for storing their customers’ health data.
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Wong, Sze-nga, and 王絲雅. "The impact of electronic health record on diabetes management : a systematic review." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193850.

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Objectives: To investigate the impact of electronic health record (EHR) on diabetes management through examination of the effectiveness of implementation of EHR and to improve the quality of care and the cost-effectiveness on the use of EHR. Methods: Three databases, PubMed, Ovid Medline and Google Scholar, were searched with specific combination keywords including electronic medical record and electronic health record, and diabetes. Quality appraisal and extraction of data were conducted on literature that met with the inclusion criteria. Results: 10 literature studies, a total of 204,251 participants with diabetes, were included in this study. All subjects, with similar demographic and clinical characteristics, were from clinic and primary care setting with the use of EHR. Different outcome measures were compared and to evaluate the effectiveness of EHR on quality of care and cost-effectiveness. Discussion: The impact of EHR on effectiveness of diabetes management, potential factors of barrier for adoption and the limitation for implementation of EHR were discussed. These suggested that further research is needed to have stronger evidence to widespread the use of EHR in Hong Kong as a future direction on public health issue. Conclusion: In this systematic review, EHR showed potential benefit in improving the quality of care and reduce the health care expenditure for long term running. Patient safety and efficiency are yet to be covered in the studies. Further research is needed on the acceptability and applicability of the use of EHR in Hong Kong.
published_or_final_version
Public Health
Master
Master of Public Health
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Song, Lihong. "Medical concept embedding with ontological representations." HKBU Institutional Repository, 2019. https://repository.hkbu.edu.hk/etd_oa/703.

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Learning representations of medical concepts from the Electronic Health Records (EHRs) has been shown effective for predictive analytics in healthcare. The learned representations are expected to preserve the semantic meanings of different medical concepts, which can be treated as features and thus benefit a variety of applications. Medical ontologies have also been explored to be integrated with the EHR data to further enhance the accuracy of various prediction tasks in healthcare. Most of the existing works assume that medical concepts under the same ontological category should share similar representations, which however does not always hold. In particular, the categorizations in the categorical medical ontologies were established with various factors being considered. Medical concepts even under the same ontological category may not follow similar occurrence patterns in the EHR data, leading to contradicting objectives for the representation learning. In addition, these existing works merely utilize the categorical ontologies. Actually, it has been noticed that ontologies containing multiple types of relations are also available. However, studies rarely make use of the diverse types of medical ontologies. In this thesis research, we propose three novel representation learning models for integrating the EHR data and medical ontologies for predictive analytics. To improve the interpretability and alleviate the conflicting objective issue between the EHR data and medical ontologies, we propose techniques to learn medical concepts embeddings with multiple ontological representations. To reduce the reliance on labeled data, we treat the co-occurrence statistics of clinical events as additional training signals, which help us learn good representations even with few labeled data. To leverage the various domain knowledge, we also consider multiple medical ontologies (CCS, ATC and SNOMED-CT) and propose corresponding attention mechanisms so as to take the best advantage of the medical ontologies with better interpretability. Our proposed models can achieve the final medical concept representations which align better with the EHR data. We conduct extensive experiments, and our empirical results prove the effectiveness of the proposed methods. Keywords: Bio/Medicine, Healthcare-AI, Electronic Health Record, Representation Learning, Machine Learning Applications
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Bickram-Shrestha, Ravi. "The patient information folder : an approach to the Electronic Patient Record." Thesis, Imperial College London, 1999. http://hdl.handle.net/10044/1/7473.

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Books on the topic "Medical records Australia Data processing"

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Melbourne, Vic ). National Health Informatics Conference (10th 2002. Improving quality by lowering barriers: HIC 2002 handbook of abstracts : Tenth National Health Informatics Conference, Melbourne, Victoria, Australia, 4-6 August 2002. Victoria, Australia: Health Informatics Society of Australia Ltd., 2002.

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Karmel, Rosemary. Comparing name-based and event-based strategies for data linkage: A study linking hospital and residential aged care data for Western Australia. Canberra: Australian Institute of Health and Welfare, 2007.

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Takeda, Hiroshi. E-Health: First IMIA/IFIP Joint Symposium, E-Health 2010, Held as Part of WCC 2010, Brisbane, Australia, September 20-23, 2010. Proceedings. Berlin, Heidelberg: IFIP International Federation for Information Processing, 2010.

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Berkovsky, Shlomo. Persuasive Technology: 8th International Conference, PERSUASIVE 2013, Sydney, NSW, Australia, April 3-5, 2013. Proceedings. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013.

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Landholt, Thomas F. Automating the medical record. Norcross, Ga: Coker Pub. Co., 1999.

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Information discovery on electronic health records. Boca Raton: Taylor & Francis, 2010.

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Susan, Dorfman, ed. Electronic health records: Strategies for long-term success. Chicago, IL: Health Administration Press, 2013.

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Exploring electronic health records. [Place of publication not identified]: Paradigm Publishing, Inc, 2014.

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Schaum's outlines medical charting. Chicago: McGraw-Hill, 2012.

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1911-, Hinohara Shigeaki, ed. Denshi karute jidai no POS: Kanja shikō no renkei iryō o suishinsuru tame ni. Tōkyō: Igaku Shoin, 2012.

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Book chapters on the topic "Medical records Australia Data processing"

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Rieger, Josef, Lenka Lhotska, Vladimir Krajca, and Milos Matousek. "Application of Quantitative Methods of Signal Processing to Automatic Classification of Long-Term EEG Records." In Biological and Medical Data Analysis, 333–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-30547-7_34.

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Wang, Huifang. "Application of the Computer Database Software in the ICU Nursing Medical Records Administration." In Data Processing Techniques and Applications for Cyber-Physical Systems (DPTA 2019), 1433–38. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-1468-5_169.

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Banham, Adam, Sander J. J. Leemans, Moe T. Wynn, and Robert Andrews. "xPM: A Framework for Process Mining with Exogenous Data." In Lecture Notes in Business Information Processing, 85–97. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-98581-3_7.

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AbstractProcess mining facilitates analysis of business processes using event logs derived from historical records of process executions stored in organisations’ information systems. Most existing process mining techniques only consider data directly related to process execution (endogenous data). Data not directly representable as attributes of either events or traces (which includes exogenous data), are generally not considered. Exogenous data may be used by process participants in making decisions about execution paths. However, as exogenous data is not represented in event logs, its impact on such decision making is opaque and cannot currently be assessed by existing process mining techniques. This paper shows how exogenous data can be used in process mining, in particular discovery and enhancement techniques, to understand its influence on process decisions. In particular, we focus on time series which represent periodic observations of e.g. weather measurements, city health alerts or patient vital signs. We show that exogenous time series can be aligned and transformed into new attributes to annotate events in an event log. Then, we use these attributes to discover preconditions in a Petri net with exogenous data (xDPN), thus revealing the exogenous data’s influence on the process. Using our framework and a real-life data set from the medical domain, we evaluate the influence of exogenous data on decision points that are non-deterministic in an xDPN.
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"Medical Records." In Macdonald on the Law of Freedom of Information, edited by John MacDonald and Ross Crail. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780198724452.003.0029.

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The law ascribes great importance to maintaining confidentiality in medical matters. Chapter 21 considers the means by which that principle is enforced at common law and by statute, lifetime exceptions to it, and whether it endures after death. The chapter discusses how to go about obtaining access to one’s own medical records under the Data Protection Act 1998, and access to the medical records of deceased persons under the Access to Health Records Act 1990. The rights of patients under the Access to Medical Reports Act 1988 to see and veto medical reports sought from their doctors by employers or insurance companies are also covered. The 2002 Regulations which authorize processing of anonymized patient information for public health and research purposes are summarized. In conclusion, the chapter looks at how the NHS undertakes to handle patients’ information in its published ‘Care Record Guarantee’.
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Yadav, Shweta, Asif Ekbal, Sriparna Saha, Parth S. Pathak, and Pushpak Bhattacharyya. "Patient Data De-Identification." In Natural Language Processing, 991–1010. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-0951-7.ch048.

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With the rapid increment in the clinical text, de-identification of patient Protected Health Information (PHI) has drawn significant attention in recent past. This aims for automatic identification and removal of the patient Protected Health Information from medical records. This paper proposes a supervised machine learning technique for solving the problem of patient data de- identification. In the current paper, we provide an insight into the de-identification task, its major challenges, techniques to address challenges, detailed analysis of the results and direction of future improvement. We extract several features by studying the properties of the datasets and the domain. We build our model based on the 2014 i2b2 (Informatics for Integrating Biology to the Bedside) de-identification challenge. Experiments show that the proposed system is highly accurate in de-identification of the medical records. The system achieves the final recall, precision and F-score of 95.69%, 99.31%, and 97.46%, respectively.
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Samanta, Jo, and Ash Samanta. "4. Confidentiality and access to medical records." In Medical Law Concentrate, 59–76. Oxford University Press, 2021. http://dx.doi.org/10.1093/he/9780198871354.003.0004.

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This chapter examines confidentiality as a fundamental aspect of doctor–patient relationships: its ethical basis and equitable, contractual, and tortious obligations. It then considers the law governing access to medical records and statute that necessitates fair and lawful processing of sensitive personal data and the EU General Data Protection Regulation aimed at harmonising data protection legislation. It discusses exceptions to the duty of confidentiality, including explicit and implied consent, prevention of harm to others, police investigation, public interests, and press freedom. The chapter considers confidentiality with respect to children; adults who lack capacity and deceased patients; remedies available for breach of confidence; access to electronic patient records; and issues raised by genetics-related information.
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Rajagopalan, Sundararaman, Siva Janakiraman, and Amirtharajan Rengarajan. "Medical Image Encryption." In Medical Data Security for Bioengineers, 278–304. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-7952-6.ch014.

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The healthcare industry has been facing a lot of challenges in securing electronic health records (EHR). Medical images have found a noteworthy position for diagnosis leading to therapeutic requirements. Millions of medical images of various modalities are generally safeguarded through software-based encryption. DICOM format is a widely used medical image type. In this chapter, DICOM image encryption implemented on cyclone FPGA and ARM microcontroller platforms is discussed. The methodology includes logistic map, DNA coding, and LFSR towards a balanced confusion – diffusion processes for encrypting 8-bit depth 256 × 256 resolution of DICOM images. For FPGA realization of this algorithm, the concurrency feature has been utilized by simultaneous processing of 128 × 128 pixel blocks which yielded a throughput of 79.4375 Mbps. Noticeably, the ARM controller which replicated this approach through sequential embedded “C” code took 1248 bytes in flash code memory and Cyclone IV FPGA consumed 21,870 logic elements for implementing the proposed encryption scheme with 50 MHz operating clock.
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El Guemhioui, Karim, and Steven A. Demurjian. "Semantic Reconciliation of Electronic Health Records Using Semantic Web Technologies." In Data Analytics in Medicine, 528–50. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1204-3.ch029.

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In this paper, the authors present an approach to reconcile the semantics of distinct medical terms found in personal health records (PHRs - that store data controlled by patients) and electronic medical records (EMRs - that store data controlled by providers) that are utilized to describe the same concept in different systems. The authors present a solution for semantic reconciliation based on RDF and related semantic web technologies. As part of the solution, the authors utilize a centralized repository of ontologies to: uniformly interrogate the medical coding systems in which those terms are defined, extract all of their published synonyms, and save the results as RDF triples. The final step in the process is to employ a reasoner to infer non-explicit synonymy among those terms, hence evidencing the underlying semantics to the PHR and EMR systems for possible further processing.
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Medhekar, Anita. "My Health Record and Emerging Cybersecurity Challenges in the Australian Digital Environment." In Research Anthology on Securing Medical Systems and Records, 428–47. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-6311-6.ch021.

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The main aim of embracing evolutionary digital e-health technologies such as ‘My Health Records' is to transform and empower the patients to control their health records, access, choose the right healthcare provider and suitable treatment, when required. It has been a challenge for the healthcare practitioners, hospital staff, as well as patients to accept, embrace, and adopt transformative digital e-health technologies and manage their healthcare records amidst concerns of slow adoption by the patient due to data privacy and cybersecurity issues. Australia, since COVID-19, has stressed the importance of secure online connectivity for the government, business, and the consumers. It is essential that My Health Record platform is cyber-safe, and user-friendly so that consumers feel conformable, safe and secure regarding their personal health records. This chapter discussed the challenges of embracing e-health digital technologies and assurance of advancing cybersecurity of online My Health Record, which will transform e-health provision and empower patients and healthcare providers.
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S., Indra Priyadharshini, Pradheeba Ulaganathan, Vigilson Prem M., and Yuvaraj B. R. "Constructive Solutions for Security and Privacy Issues at the Edge." In Research Anthology on Securing Medical Systems and Records, 294–321. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-6311-6.ch015.

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The evolution in computing strategies has shown wonders in reducing the reachability issue among different end devices. After centralized approaches, decentralized approaches started to take action, but with the latency in data pre-processing, computing very simple requests was the same as for the larger computations. Now it's time to have a simple decentralized environment called edge that is created very near to the end device. This makes edge location friendly and time friendly to different kinds of devices like smart, sensor, grid, etc. In this chapter, some of the serious and non-discussed security issues and privacy issues available on edge are explained neatly, and for a few of the problems, some solutions are also recommended. At last, a separate case study of edge computing challenges in healthcare is also explored, and solutions to those issues concerning that domain are shown.
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Conference papers on the topic "Medical records Australia Data processing"

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Gloria, Chrismatovanie. "Compliance with Complete Filling of Patient's Medical Record at Hospital: A Systematic Review." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.04.29.

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ABSTRACT Background: The health information system, especially medical records in hospitals must be carried out accurately and completely. Medical records are important as evidence for the courts, education, research, and policy makers. This study aimed to investigate the factors affecting the compliance with completeness of filling patient’s medical re­cords at hospitals. Subjects and Methods: A systematic review was conducted by searching from Pro­Quest, Scopus, and National journals using keywords medical records, filling of medical records, and non- compliance filling medical records. The abstracts and full-text arti­cles published between 2014 to 2019 were selected for this review. A total of 62,355 arti­cles were conducted screening of eligibility criteria. The data were reported using PRIS­MA flow chart. Results: Eleven articles consisting of eight articles using observational studies and three articles using experimental studies met the eligible criteria. There were two articles analyzed systematically from the United States and India, two articles reviewed literature from the United States and England, and seven articles were analyzed statis­tically from Indonesia, America, Australia, and Europe. Six articles showed the sig­nificant results of the factors affecting non-compliance on the medical records filling at the Hospitals. Conclusion: Non-compliance with medical record filling was found in the hospitals under study. Health professionals are suggested to fill out the medical record com­pletely. The hos­pital should enforce compliance with complete medical record fill­ing by health professionals. Keywords: medical record, compliance, hospital Correspondence: Chrismatovanie Gloria. Hospital Administration Department, Faculty Of Public Health, Uni­­ver­sitas Indonesia, Depok, West Java. Email: chrismatovaniegloria@gmail.com. Mo­­­­bi­le: +628132116­1896 DOI: https://doi.org/10.26911/the7thicph.04.29
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Tharaud, Jeremie, Sven Wohlgemuth, Isao Echizen, Noboru Sonehara, Gunter Muller, and Pascal Lafourcade. "Privacy by Data Provenance with Digital Watermarking - A Proof-of-Concept Implementation for Medical Services with Electronic Health Records." In 2010 Sixth International Conference on Intelligent Information Hiding and Multimedia Signal Processing (IIH-MSP). IEEE, 2010. http://dx.doi.org/10.1109/iihmsp.2010.130.

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Gritz, Raquel A. J., Rafael S. Pereira, Henrique Matheus F. da Silva, Henrique G. Zatti, Laura E. A. Viana, Karol C. S. F. Navarro, Thalita R. Dias, et al. "An Ontology Based Natural Language Processing Pipeline for Brazilian COVID-19 EMR." In Brazilian e-Science Workshop. Sociedade Brasileira de Computação, 2021. http://dx.doi.org/10.5753/bresci.2021.15794.

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COVID-19 became a pandemic infecting more than 100 million people across the world and has been going on for over a year. A huge amount of data has been produced as electronic medical records in the form of textual data because of patient visits. Extracting this information may be very useful in better understanding the COVID-19 disease. However, challenges exist in interpreting the medical records typed as free text as doctors may use different terms to type in their observations. In order to deal with the latter, we created an ontology in Portuguese to describe the terms used in COVID-19 medical records in Brazil. In this paper, we present a brief overview of the ontology and how we are using it as the first step of a more complex NLP task.
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Pizarro, Jorge, Byron Vásquez, Willan Steven Mendieta Molina, and Remigio Hurtado. "Hepatitis predictive analysis model through deep learning using neural networks based on patient history." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001449.

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First of all, one of the applications of artificial intelligence is the prediction of diseases, including hepatitis. Hepatitis has been a recurring disease over the years as it seriously affects the population, increasing by 125,000 deaths per year. This process of inflammation and damage to the organ affects its performance, as well as the functioning of the other organs in the body. In this work, an analysis of variables and their influence on the objective variable is made, in addition, results are presented from a predictive model.We propose a predictive analysis model that incorporates artificial neural networks and we have compared this prediction method with other classification-oriented models such as support vector machines (SVM) and genetic algorithms. We have conducted our method as a classification problem. This method requires a prior process of data processing and exploratory analysis to identify the variables or factors that directly influence this type of disease. In this way, we will be able to identify the variables that intervene in the development of this disease and that affect the liver or the correct functioning of this organ, presenting discomfort to the human body, as well as complications such as liver failure or liver cancer. Our model is structured in the following steps: first, data extraction is performed, which was collected from the machine learning repository of the University of California at Irvine (UCI). Then these data go through a variable transformation process. Subsequently, it is processed with learning and optimization through a neural network. The optimization (fine-tuning) is performed in three phases: complication hyperparameter optimization, neural network layer density optimization, and finally dropout regularization optimization. Finally, the visualization and analysis of results is carried out. We have used a data set of patient medical records, among the variables are: age, sex, gender, hemoglobin, etc. We have found factors related either indirectly or directly to the disease. The results of the model are presented according to the quality measures: Recall, Precision and MAE.We can say that this research leaves the doors open to new challenges such as new implementations within the field of medicine, not only focused on the liver, but also being able to extend the development environment to other applications and organs of the human body in order to avoid risks possible, or future complications. It should be noted that the future of applications with the use of artificial neural networks is constantly evolving, the application of improved models such as the use of random forests, assembly algorithms show a great capacity for application both in biomedical engineering and in focused areas to the analysis of different types of medical images.
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Noever, David, Josh Kalin, Matthew Ciolino, Dom Hambrick, and Gerry Dozier. "Local Translation Services for Neglected Languages." In 8th International Conference on Artificial Intelligence and Applications (AIAP 2021). AIRCC Publishing Corporation, 2021. http://dx.doi.org/10.5121/csit.2021.110110.

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Taking advantage of computationally lightweight, but high-quality translators prompt consideration of new applications that address neglected languages. For projects with protected or personal data, translators for less popular or low-resource languages require specific compliance checks before posting to a public translation API. In these cases, locally run translators can render reasonable, cost-effective solutions if done with an army of offline, smallscale pair translators. Like handling a specialist’s dialect, this research illustrates translating two historically interesting, but obfuscated languages: 1) hacker-speak (“l33t”) and 2) reverse (or “mirror”) writing as practiced by Leonardo da Vinci. The work generalizes a deep learning architecture to translatable variants of hacker-speak with lite, medium, and hard vocabularies. The original contribution highlights a fluent translator of hacker-speak in under 50 megabytes and demonstrates a companion text generator for augmenting future datasets with greater than a million bilingual sentence pairs. A primary motivation stems from the need to understand and archive the evolution of the international computer community, one that continuously enhances their talent for speaking openly but in hidden contexts. This training of bilingual sentences supports deep learning models using a long short-term memory, recurrent neural network (LSTM-RNN). It extends previous work demonstrating an English-to-foreign translation service built from as little as 10,000 bilingual sentence pairs. This work further solves the equivalent translation problem in twenty-six additional (non-obfuscated) languages and rank orders those models and their proficiency quantitatively with Italian as the most successful and Mandarin Chinese as the most challenging. For neglected languages, the method prototypes novel services for smaller niche translations such as Kabyle (Algerian dialect) which covers between 5-7 million speakers but one which for most enterprise translators, has not yet reached development. One anticipates the extension of this approach to other important dialects, such as translating technical (medical or legal) jargon and processing health records or handling many of the dialects collected from specialized domains (mixed languages like “Spanglish”, acronym-laden Twitter feeds, or urban slang).
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Reports on the topic "Medical records Australia Data processing"

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Rankin, Nicole, Deborah McGregor, Candice Donnelly, Bethany Van Dort, Richard De Abreu Lourenco, Anne Cust, and Emily Stone. Lung cancer screening using low-dose computed tomography for high risk populations: Investigating effectiveness and screening program implementation considerations: An Evidence Check rapid review brokered by the Sax Institute (www.saxinstitute.org.au) for the Cancer Institute NSW. The Sax Institute, October 2019. http://dx.doi.org/10.57022/clzt5093.

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Background Lung cancer is the number one cause of cancer death worldwide.(1) It is the fifth most commonly diagnosed cancer in Australia (12,741 cases diagnosed in 2018) and the leading cause of cancer death.(2) The number of years of potential life lost to lung cancer in Australia is estimated to be 58,450, similar to that of colorectal and breast cancer combined.(3) While tobacco control strategies are most effective for disease prevention in the general population, early detection via low dose computed tomography (LDCT) screening in high-risk populations is a viable option for detecting asymptomatic disease in current (13%) and former (24%) Australian smokers.(4) The purpose of this Evidence Check review is to identify and analyse existing and emerging evidence for LDCT lung cancer screening in high-risk individuals to guide future program and policy planning. Evidence Check questions This review aimed to address the following questions: 1. What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? 2. What is the evidence of potential harms from lung cancer screening for higher-risk individuals? 3. What are the main components of recent major lung cancer screening programs or trials? 4. What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Summary of methods The authors searched the peer-reviewed literature across three databases (MEDLINE, PsycINFO and Embase) for existing systematic reviews and original studies published between 1 January 2009 and 8 August 2019. Fifteen systematic reviews (of which 8 were contemporary) and 64 original publications met the inclusion criteria set across the four questions. Key findings Question 1: What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? There is sufficient evidence from systematic reviews and meta-analyses of combined (pooled) data from screening trials (of high-risk individuals) to indicate that LDCT examination is clinically effective in reducing lung cancer mortality. In 2011, the landmark National Lung Cancer Screening Trial (NLST, a large-scale randomised controlled trial [RCT] conducted in the US) reported a 20% (95% CI 6.8% – 26.7%; P=0.004) relative reduction in mortality among long-term heavy smokers over three rounds of annual screening. High-risk eligibility criteria was defined as people aged 55–74 years with a smoking history of ≥30 pack-years (years in which a smoker has consumed 20-plus cigarettes each day) and, for former smokers, ≥30 pack-years and have quit within the past 15 years.(5) All-cause mortality was reduced by 6.7% (95% CI, 1.2% – 13.6%; P=0.02). Initial data from the second landmark RCT, the NEderlands-Leuvens Longkanker Screenings ONderzoek (known as the NELSON trial), have found an even greater reduction of 26% (95% CI, 9% – 41%) in lung cancer mortality, with full trial results yet to be published.(6, 7) Pooled analyses, including several smaller-scale European LDCT screening trials insufficiently powered in their own right, collectively demonstrate a statistically significant reduction in lung cancer mortality (RR 0.82, 95% CI 0.73–0.91).(8) Despite the reduction in all-cause mortality found in the NLST, pooled analyses of seven trials found no statistically significant difference in all-cause mortality (RR 0.95, 95% CI 0.90–1.00).(8) However, cancer-specific mortality is currently the most relevant outcome in cancer screening trials. These seven trials demonstrated a significantly greater proportion of early stage cancers in LDCT groups compared with controls (RR 2.08, 95% CI 1.43–3.03). Thus, when considering results across mortality outcomes and early stage cancers diagnosed, LDCT screening is considered to be clinically effective. Question 2: What is the evidence of potential harms from lung cancer screening for higher-risk individuals? The harms of LDCT lung cancer screening include false positive tests and the consequences of unnecessary invasive follow-up procedures for conditions that are eventually diagnosed as benign. While LDCT screening leads to an increased frequency of invasive procedures, it does not result in greater mortality soon after an invasive procedure (in trial settings when compared with the control arm).(8) Overdiagnosis, exposure to radiation, psychological distress and an impact on quality of life are other known harms. Systematic review evidence indicates the benefits of LDCT screening are likely to outweigh the harms. The potential harms are likely to be reduced as refinements are made to LDCT screening protocols through: i) the application of risk predication models (e.g. the PLCOm2012), which enable a more accurate selection of the high-risk population through the use of specific criteria (beyond age and smoking history); ii) the use of nodule management algorithms (e.g. Lung-RADS, PanCan), which assist in the diagnostic evaluation of screen-detected nodules and cancers (e.g. more precise volumetric assessment of nodules); and, iii) more judicious selection of patients for invasive procedures. Recent evidence suggests a positive LDCT result may transiently increase psychological distress but does not have long-term adverse effects on psychological distress or health-related quality of life (HRQoL). With regards to smoking cessation, there is no evidence to suggest screening participation invokes a false sense of assurance in smokers, nor a reduction in motivation to quit. The NELSON and Danish trials found no difference in smoking cessation rates between LDCT screening and control groups. Higher net cessation rates, compared with general population, suggest those who participate in screening trials may already be motivated to quit. Question 3: What are the main components of recent major lung cancer screening programs or trials? There are no systematic reviews that capture the main components of recent major lung cancer screening trials and programs. We extracted evidence from original studies and clinical guidance documents and organised this into key groups to form a concise set of components for potential implementation of a national lung cancer screening program in Australia: 1. Identifying the high-risk population: recruitment, eligibility, selection and referral 2. Educating the public, people at high risk and healthcare providers; this includes creating awareness of lung cancer, the benefits and harms of LDCT screening, and shared decision-making 3. Components necessary for health services to deliver a screening program: a. Planning phase: e.g. human resources to coordinate the program, electronic data systems that integrate medical records information and link to an established national registry b. Implementation phase: e.g. human and technological resources required to conduct LDCT examinations, interpretation of reports and communication of results to participants c. Monitoring and evaluation phase: e.g. monitoring outcomes across patients, radiological reporting, compliance with established standards and a quality assurance program 4. Data reporting and research, e.g. audit and feedback to multidisciplinary teams, reporting outcomes to enhance international research into LDCT screening 5. Incorporation of smoking cessation interventions, e.g. specific programs designed for LDCT screening or referral to existing community or hospital-based services that deliver cessation interventions. Most original studies are single-institution evaluations that contain descriptive data about the processes required to establish and implement a high-risk population-based screening program. Across all studies there is a consistent message as to the challenges and complexities of establishing LDCT screening programs to attract people at high risk who will receive the greatest benefits from participation. With regards to smoking cessation, evidence from one systematic review indicates the optimal strategy for incorporating smoking cessation interventions into a LDCT screening program is unclear. There is widespread agreement that LDCT screening attendance presents a ‘teachable moment’ for cessation advice, especially among those people who receive a positive scan result. Smoking cessation is an area of significant research investment; for instance, eight US-based clinical trials are now underway that aim to address how best to design and deliver cessation programs within large-scale LDCT screening programs.(9) Question 4: What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Assessing the value or cost-effectiveness of LDCT screening involves a complex interplay of factors including data on effectiveness and costs, and institutional context. A key input is data about the effectiveness of potential and current screening programs with respect to case detection, and the likely outcomes of treating those cases sooner (in the presence of LDCT screening) as opposed to later (in the absence of LDCT screening). Evidence about the cost-effectiveness of LDCT screening programs has been summarised in two systematic reviews. We identified a further 13 studies—five modelling studies, one discrete choice experiment and seven articles—that used a variety of methods to assess cost-effectiveness. Three modelling studies indicated LDCT screening was cost-effective in the settings of the US and Europe. Two studies—one from Australia and one from New Zealand—reported LDCT screening would not be cost-effective using NLST-like protocols. We anticipate that, following the full publication of the NELSON trial, cost-effectiveness studies will likely be updated with new data that reduce uncertainty about factors that influence modelling outcomes, including the findings of indeterminate nodules. Gaps in the evidence There is a large and accessible body of evidence as to the effectiveness (Q1) and harms (Q2) of LDCT screening for lung cancer. Nevertheless, there are significant gaps in the evidence about the program components that are required to implement an effective LDCT screening program (Q3). Questions about LDCT screening acceptability and feasibility were not explicitly included in the scope. However, as the evidence is based primarily on US programs and UK pilot studies, the relevance to the local setting requires careful consideration. The Queensland Lung Cancer Screening Study provides feasibility data about clinical aspects of LDCT screening but little about program design. The International Lung Screening Trial is still in the recruitment phase and findings are not yet available for inclusion in this Evidence Check. The Australian Population Based Screening Framework was developed to “inform decision-makers on the key issues to be considered when assessing potential screening programs in Australia”.(10) As the Framework is specific to population-based, rather than high-risk, screening programs, there is a lack of clarity about transferability of criteria. However, the Framework criteria do stipulate that a screening program must be acceptable to “important subgroups such as target participants who are from culturally and linguistically diverse backgrounds, Aboriginal and Torres Strait Islander people, people from disadvantaged groups and people with a disability”.(10) An extensive search of the literature highlighted that there is very little information about the acceptability of LDCT screening to these population groups in Australia. Yet they are part of the high-risk population.(10) There are also considerable gaps in the evidence about the cost-effectiveness of LDCT screening in different settings, including Australia. The evidence base in this area is rapidly evolving and is likely to include new data from the NELSON trial and incorporate data about the costs of targeted- and immuno-therapies as these treatments become more widely available in Australia.
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