Academic literature on the topic 'Medical Diagnostics - Bio-sensors'

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Journal articles on the topic "Medical Diagnostics - Bio-sensors"

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D’Orazio, Paul A., Thomas C. Maley, Robert R. McCaffrey, Andy C. Chan, Donna Orvedahl, Joe Foos, David Blake, et al. "Planar (Bio)Sensors for Critical Care Diagnostics." Clinical Chemistry 43, no. 9 (September 1, 1997): 1804–5. http://dx.doi.org/10.1093/clinchem/43.9.1804.

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Mondal, Himadri Shekhar, Md Mahbub Hossain, Md Mehadi Hasan Mahasin, Pankoj Kumar Mondal, and Md Ekhlasur Rahaman. "Emerging Applications of Optical Bio-Sensors." Journal of Biomimetics, Biomaterials and Biomedical Engineering 40 (February 2019): 41–55. http://dx.doi.org/10.4028/www.scientific.net/jbbbe.40.41.

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In the simplest words, a bio-sensor is an analytic device. In recent years, bio-sensors have shown emerging contribution in medical diagnosis, drug discovery, and treatment process. In this regards, continuous research is ongoing and many more features are being added in the sensing technologies. Optical sensing technology is no more bound in research area but also in the commercial use for the betterment of mankind. There are different types of bio-sensors particularly optical which have already been developed and research is going to expand many more of them. Sensing applications are not limited in glucose, DNA, cancer cell detection, drug discovery, immunological, Hepatitis B virus, and enzyme detection but also many more development is knocking at the door. Therefore, this review paper is focused on the applications and functions of bio-sensors (especially optical) in medical diagnostics and treatment.
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Bilbao, Emanuel, Octavio Garate, Theo Rodríguez Campos, Mariano Roberti, Mijal Mass, Alex Lozano, Gloria Longinotti, Leandro Monsalve, and Gabriel Ybarra. "Electrochemical Sweat Sensors." Chemosensors 11, no. 4 (April 14, 2023): 244. http://dx.doi.org/10.3390/chemosensors11040244.

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Sweat analysis by means of minimally invasive wearable sensors is considered a potentially disruptive method for assessing clinical parameters, with exciting applications in early medical diagnostics and high-performance sports. Electrochemical sensors and biosensors are especially attractive because of the possibility of the electronic integration of wearable devices. In this article, we review several aspects regarding the potentialities and present limitations of electrochemical sweat (bio)sensors, including: the main target analytes and their relationships with clinical conditions; most usual electrochemical techniques of transduction used according to the nature of the target analytes; issues connected to the collection of representative sweat samples; aspects regarding the associated, miniaturized electronic instrumentation used for signal processing and communication; and signal processing by machine learning.
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Popov, Alexander Mikhailovich. "NUMERICAL STUDY OF QUANTUM DOT SPECTRUM CALCULATION ON THE BASE OF MONTE CARLO METHOD." Computational nanotechnology 6, no. 3 (September 30, 2019): 74–79. http://dx.doi.org/10.33693/2313-223x-2019-6-3-74-79.

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The work is directed to numerical simulation of quantum dots spectrum for molecular nanostructure of small size for creation of new nanotechnology. Quantum dots are the small peaces of semiconductor which presents the molecular system heterostucture. The cariers of charge are confined in small region. The main acsent is made on development of effective method for determination of eigenfuncions and eigenvalues of quantum dot. Quantum dots are used in nanoelectronics, in bio-sensors of nanosize, and in the systems of medical diagnostics of high precision.
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Xu, Jing, Yunsheng Fang, and Jun Chen. "Wearable Biosensors for Non-Invasive Sweat Diagnostics." Biosensors 11, no. 8 (July 23, 2021): 245. http://dx.doi.org/10.3390/bios11080245.

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Recent advances in microfluidics, microelectronics, and electrochemical sensing methods have steered the way for the development of novel and potential wearable biosensors for healthcare monitoring. Wearable bioelectronics has received tremendous attention worldwide due to its great a potential for predictive medical modeling and allowing for personalized point-of-care-testing (POCT). They possess many appealing characteristics, for example, lightweight, flexibility, good stretchability, conformability, and low cost. These characteristics make wearable bioelectronics a promising platform for personalized devices. In this paper, we review recent progress in flexible and wearable sensors for non-invasive biomonitoring using sweat as the bio-fluid. Real-time and molecular-level monitoring of personal health states can be achieved with sweat-based or perspiration-based wearable biosensors. The suitability of sweat and its potential in healthcare monitoring, sweat extraction, and the challenges encountered in sweat-based analysis are summarized. The paper also discusses challenges that still hinder the full-fledged development of sweat-based wearables and presents the areas of future research.
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Spychalska, Kamila, Dorota Zając, Sylwia Baluta, Kinga Halicka, and Joanna Cabaj. "Functional Polymers Structures for (Bio)Sensing Application—A Review." Polymers 12, no. 5 (May 18, 2020): 1154. http://dx.doi.org/10.3390/polym12051154.

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In this review we present polymeric materials for (bio)sensor technology development. We focused on conductive polymers (conjugated microporous polymer, polymer gels), composites, molecularly imprinted polymers and their influence on the design and fabrication of bio(sensors), which in the future could act as lab-on-a-chip (LOC) devices. LOC instruments enable us to perform a wide range of analysis away from the stationary laboratory. Characterized polymeric species represent promising candidates in biosensor or sensor technology for LOC development, not only for manufacturing these devices, but also as a surface for biologically active materials’ immobilization. The presence of biological compounds can improve the sensitivity and selectivity of analytical tools, which in the case of medical diagnostics is extremely important. The described materials are biocompatible, cost-effective, flexible and are an excellent platform for the anchoring of specific compounds.
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Kadhum, F. J., S. H. Kafi, A. J. Karam, A. A. Al-Zuky, M. F. H. Al-Kadhemy, and A. H. Al- Saleh. "Simulation of surface plasmon resonance (SPR) layers of gold with silicon nitride as a Bi-layer biosensor." Digest Journal of Nanomaterials and Biostructures 17, no. 2 (April 2022): 623–33. http://dx.doi.org/10.15251/djnb.2022.172.623.

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Surface Plasmon Resonance (SPR) has gotten a lot of attention in biomedical sensing. Many applications in medical diagnostics and single molecule detection have sparked interest in bio-sensing techniques. Surface Plasmon resonance (SPR) is an important phenomenon used for building sensors especially in the Biological fields. Simulation analysis (in Mat lab) has been made for SPR for gold (Au) layer with thickness (40 nm) and layer of silicon nitride (Si3N4) with different thickness (10- 70 nm) step 10, deposited on glass prism type N-LASF9_ glass with the sensitive layer was water at refractive index (∆n = 0, 0.01, 0.05 and 0.1). The analysis was taken for different wavelengths from UltraViolet wavelength 100 nm to Near Infra- Red wavelength 1000 nm. The properties of the surface Plasmon resonance angle (θSPR) have been calculated from plotted reflectance against incident angle θincid shows sharper resonance dip, narrower full width half maximum (FWHM), SPR dip length (Ld) increased so that improve in properties SPR and system. The SPR sensitivity (S) was calculated and recorded higher sensitivity about 134.
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Misbakhova, A. G., A. R. Abdrakhmanov, and A. R. Belyaev. "Laser technologies in the management of patients with complicated forms of sexually transmitted infections." Kazan medical journal 101, no. 2 (April 13, 2020): 289–95. http://dx.doi.org/10.17816/kmj2020-289.

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Aim. To study and assess the clinical effectiveness of medical laser technologies in the complex treatment of complicated forms of sexually transmitted infections (STIs). Methods. Modern technologies of molecular biological laboratory diagnostics in real time with Real-time amplifier CFX96 Bio-Rad Laboratorias (USA), were used for etiological diagnostics of pathogens. Determination of infectious and inflammatory lesions of tissues of the genital system was carried out using ultrasound on ALOKA CCL-680 device (Japan) using cavity sensors with an operating frequency of 5 MHz. Drug therapy was carried out in accordance with the Federal clinical recommendations of the Russian society of dermatovenerologists and cosmetologists Dermatovenerology (Moscow, 2015). To assess the effectiveness of laser technologies in complex treatment, patients with complicated forms of STIs were randomly divided into 2 groups: the control group (32 patients), where only traditional therapy was used, and the main group (108 patients), in which, in addition to traditional therapy, treatment was supplemented with laser therapy. Results. The effectiveness of antibiotic therapy in the main group was 14.0%, and treatment using laser technology was 33.1% higher than the effectiveness of treatment in the control group. This shows the effectiveness of laser technologies in the treatment of infectious and inflammatory structural changes in the tissues of the organs of the reproductive system. Conclusion. The use of medical laser technologies in the treatment of complicated forms of STIs with a change in exposure parameters depending on the revealed inflammatory-structural changes in the tissues of the affected organs showed high efficiency (79.6%); this technology can be recommended for use in practical health care for the treatment of complicated forms of STIs.
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Nikiforov, K. A. "Advanced Molecular-Genetic Methods and Prospects for Their Application for the Indication and Identification of <i>Yersinia pestis</i> Strains." Problems of Particularly Dangerous Infections, no. 4 (February 11, 2023): 29–40. http://dx.doi.org/10.21055/0370-1069-2022-4-29-40.

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The review provides an analysis of the literature data on the use of various modern molecular-genetic methods for the indication and identification of Yersinia pestis strains with different properties and degree of virulence, which is caused by the diverse natural conditions in which they circulate. The methods are also considered from the perspective of their promising application at three levels (territorial, regional and federal) of the system for laboratory diagnosis of infectious diseases at the premises of Rospotrebnadzor organizations to solve the problem of maintaining the sanitary and epidemiological well-being of the country’s population. The main groups of methods considered are as follows: based on the analysis of the lengths of restriction fragments (ribo- and IS-typing, pulse gel electrophoresis); based on the analysis of specific fragments (DFR typing, VNTR typing); based on sequencing (MLST, CRISPR analysis, SNP analysis); PCR methods (including IPCR, SPA); isothermal amplification methods (LAMP, HDA, RPA, SEA, PCA, SHERLOCK); DNA-microarray; methods using aptamer technology; bio- and nano-sensors; DNA origami; methods based on neural networks. We can conclude that the rapid development of molecular diagnostics and genetics is aimed at increasing efficiency, multi-factorial approaches and simplifying the application of techniques with no need for expensive equipment and highly qualified personnel for analysis. At all levels of the system for laboratory diagnosis of infectious diseases at the Rospotrebnadzor organizations, it is possible to use methods based on PCR, isothermal amplification, SHERLOCK, biosensors, and small-sized sequencing devices. At the territorial level, at plague control stations, the use of immuno-PCR and SPA for the indication of Y. pestis is viable. At the regional level, introduction of the technologies based on the use of aptamers and DNA chips looks promising. For the federal level, the use of DNA origami methods and new technologies of whole genome sequencing is a prospect within the framework of advanced identification, molecular typing and sequencing of the genomes of plague agent strains.
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Kozitsina, Alisa, Tatiana Svalova, Natalia Malysheva, Andrei Okhokhonin, Marina Vidrevich, and Khiena Brainina. "Sensors Based on Bio and Biomimetic Receptors in Medical Diagnostic, Environment, and Food Analysis." Biosensors 8, no. 2 (April 1, 2018): 35. http://dx.doi.org/10.3390/bios8020035.

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Book chapters on the topic "Medical Diagnostics - Bio-sensors"

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Luedi, H. "Challenges in the development of (bio)chemical sensors for whole blood medical diagnostic applications." In Frontiers in Biosensorics II, 141–48. Basel: Birkhäuser Basel, 1997. http://dx.doi.org/10.1007/978-3-0348-9045-8_10.

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Pandey, S. P., P. Jangied, T. Shukla, Tripathi A., and N. Upmanyu. "Accounts on the Nano-carrier System for Diagnosis Purposes." In Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective, 280–320. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080506123010013.

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Timely diagnosis of critical diseases, such as cancer, may help in its effective management and better survival. Several techniques like magnetic resonance imaging (MRI), computed tomography scan (CT scan), positron emission tomography (PET), photoacoustic imaging (PAI), etc. are already being used successfully, but sometimes their high cost, spatial resolution, sensitivity, and specificity (associated with the use of contrast agent) have been questionable. The distinction between benign and malignant tumours in their early stages is also a critical issue with such methods. But the use of nano-carriers for diagnostic and theranostics purposes has opened newer dimensions and provided a better understanding and visualization of the pathophysiological condition in a specific disease. There are different nanotechnology-based systems like bio-labels containing nanoparticles, nanotechnology-based microarrays, nano-bio sensors, and nanoscale optics that can be used in molecular diagnostics. Several nano-carriers, especially after their surface functionalization, are also on the floor, showing their importance in the medical diagnosis of different diseases. The current chapter deals with the importance and significance of such different nano-carriers in the development of diagnostics and theranostics.
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Conference papers on the topic "Medical Diagnostics - Bio-sensors"

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Prashanth, Gurusiddhappa R., Shivananju B. Nanjunda, Sundarrajan Asokan, and Manoj M. Varma. "Real-time bio(chemical)sensing with etched clad fiber Bragg grating sensors." In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XII. SPIE, 2012. http://dx.doi.org/10.1117/12.907317.

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Komirisetty, Archana, Frances Williams, Aswini Pradhan, and Meric Arslan. "Integrating Sensors With Nanostructures for Biomedical Applications." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93121.

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This paper presents the fabrication of sensors that are integrated with nanostructures and bio-functionalized to create novel devices for biomedical applications. Biosensors are in great demand for various applications including for the agriculture and food industries, environmental monitoring, and medical diagnostics. Much research is being focused on the use of nanostructures (nanowires, nanotubes, nanoparticles, etc.) to provide for miniaturization and improved performance of these devices. The use of nanostructures is favorable for such applications since their sizes are closer to that of biological and chemical species and therefore, improve the signal generated. Moreover, their high surface-to-volume ratio results in devices with very high sensitivity. The use of nanotechnology leads to smaller, lower-power smart devices. Thus, this paper presents the integration of sensors with nanostructures for biomedical applications, specifically, glucose sensing. In the work presented, a glucose biosensor and its fabrication process flow are described. The device is based on electrochemical sensing using a working electrode with bio-functionalized zinc oxide (ZnO) nano-rods. Among all metal oxide nanostructures, ZnO nano-materials play a significant role as a sensing element in biosensors due to their properties such as high isoelectric point (IEP), fast electron transfer, non-toxicity, biocompatibility, and chemical stability which are very crucial parameters to achieve high sensitivity. Amperometric enzyme electrodes based on glucose oxidase (GOx) are used due to their stability and high selectivity to glucose. The device also consists of silicon dioxide and titanium layers as well as platinum working and counter electrodes and a silver/silver chloride reference electrode. The chlorination process on the reference electrode was optimized for various times using field emission scanning electron microscope (FESEM) and energy-dispersive X-ray spectroscopy (EDS or EDX) measurements. The ZnO nanorods were grown using the hydrothermal method and will be bio-functionalized with GOx for electrochemical sensing. Once completed, the sensors will be tested to characterize their performance, including their sensitivity and stability.
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Lucas, Pierre, Shibin Jiang, Garrett Coleman, Julien Ari, and Tao Luo. "Towards high-strength infrared optical fibers for bio-sensing (Conference Presentation)." In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XX, edited by Israel Gannot. SPIE, 2020. http://dx.doi.org/10.1117/12.2554631.

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Azkune, Mikel, Eneko Arrospide, Amaia Berganza, Iñaki Bikandi, Gotzon Aldabaldetreku, Gaizka Durana, and Joseba Zubia. "A novel liquid-filled microstructured polymer optical fiber as bio-sensing platform for Raman spectroscopy." In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII, edited by Israel Gannot. SPIE, 2018. http://dx.doi.org/10.1117/12.2292432.

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