Relevant bibliographies by topics / Medical Biochemistry

Academic literature on the topic 'Medical Biochemistry'

Author: Grafiati
Published: 4 June 2021
Last updated: 28 July 2024

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Contents

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Medical Biochemistry.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Medical Biochemistry"

1

Jovičić, Snežana, and Nada Majkić-Singh. "Medical Biochemistry as Subdiscipline of Laboratory Medicine in Serbia." Journal of Medical Biochemistry 36, no. 2 (April 1, 2017): 177–86. http://dx.doi.org/10.1515/jomb-2017-0010.

Full text
Abstract:
SummaryMedical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline of the laboratory medicine in Serbia. It includes all aspects of clinical chemistry, and also laboratory hematology with coagulation, immunology, etc. Medical biochemistry laboratories in Serbia and medical biochemists as a profession are part of Health Care System and their activities are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists (Clinical Chemists) in Serbia dates from 1945, when the Department of Medical Biochemistry was established at the Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate study program was established, educating Medical Biochemists under a special program. Since the academic year 2006/2007 the new five year undergraduate (according to Bologna Declaration) and four-year postgraduate program according to EC4 European Syllabus for Postgraduate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredited these programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Study of Medical Biochemistry), successful completion of the professional exam at the Ministry of Health after completion of one additional year of obligatory practical training in the medical biochemistry laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by the Serbian Chamber of Medical Biochemists. In order to present laboratory medical biochemistry practice in Serbia this paper will be focused on the following: Serbian national legislation, healthcare services organization, sub-disciplines of laboratory medicine and medical biochemistry as the most significant, education in medical biochemistry, conditions for professional practice in medical biochemistry, continuous quality improvement, and accreditation. Serbian healthcare is based on fundamental principles of universal health coverage and solidarity between all citizens.
APA, Harvard, Vancouver, ISO, and other styles
2

Majkić-Singh, Nada. "Education and Recognition of Professional Qualifications in the Field of Medical Biochemistry in Serbia." Journal of Medical Biochemistry 30, no. 4 (October 1, 2011): 279–86. http://dx.doi.org/10.2478/v10011-011-0013-7.

Full text
Abstract:
Education and Recognition of Professional Qualifications in the Field of Medical Biochemistry in Serbia Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline of the laboratory medicine in Serbia. It includes all aspects of clinical chemistry, and also laboratory hematology with coagulation, immunology, etc. Medical biochemistry laboratories in Serbia and medical biochemists as a profession are part of Health Care System and their activities are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists (Clinical Chemists) in Serbia dates from 1945, when the Department of Medical Biochemistry was established at the Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate branch was established, educating Medical Biochemists under a special program. Since school-year 2006/2007 the new five year undergraduate (according to Bologna Declaration) and postgraduate program of four-year specialization according to EC4 European Syllabus for Post-Gradate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredits the programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Study of Medical Biochemistry), successful completion of the profession exam at the Ministry of Health after completion of one additional year of obligatory practical training in the medical biochemistry laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by the Serbian Chamber of Medical Biochemists. The process of recognition of a foreign higher education document for field of medical biochemistry is initiated on request by Candidate. The process of recognition of foreign higher education documents is performed by the University. In the process of recognition in Serbia national legislations are applied as well as international legal documents of varying legal importance.
APA, Harvard, Vancouver, ISO, and other styles
3

Majkic-Singh, Nada. "Society of medical biochemists of Serbia and Montenegro: 50 years anniversary." Jugoslovenska medicinska biohemija 24, no. 3 (2005): 157–70. http://dx.doi.org/10.2298/jmh0503157m.

Full text
Abstract:
Medical biochemistry (synonyms: clinical chemistry or clinical biochemistry) in the terms of professional and scientific discipline, stems from and/or has developed along with the natural sciences and its influences (mathematics, physics, chemistry and biochemistry) and medical sciences as well (physiology, genetics, cell biology). As a scientific discipline, medical biochemistry studies metabolic processes of physiological and pathological changes with humans and animals. Applying analytical chemistry's and biochemistry's techniques enables medical biochemists to gain plenty of information related to diagnosis and prognosis which serve physicians to asses the gravity of illness and prescribe healing therapy. Therefore medical biochemistry is an integral part of modern medicine. This discipline was dubbed various, often confusing names such as pathology, physiology, clinical biology, clinical pathology, chemical pathology, clinical biochemistry, medical biochemistry, clinical chemistry and laboratory medicine, all depending on place of origin. The official, internationally accepted name - clinical chemistry, was mentioned for the first time in 1912 by Johan Scherer, who described his laboratory as Clinical Chemistry Laboratory (Klinisch Chemische Laboratorium) in the hospital Julius in Wurzburg in Germany. After creating national societies of clinical chemists, Professor Earl J. King of Royal Postgraduate Medical School from London incited an initiative to unite national societies into the organization with worldwide character - it was the International Association of Clinical Biochemists, monitored by the International Union for Pure and Applied Chemistry (IUPAC). On 24 July 1952 in Paris, a Second International Congress of Biochemistry was held. A year later, in Stockholm, the name of a newly formed association was altered into International Federation of Clinical Chemistry, which was officially accepted in 1955 in Brussels. Today this federation-s name is International Federation for Clinical Chemistry and Laboratory Medicine (IFCC). Right after the World War II our medical biochemists began to gather within their expert societies. Even before 1950 Pharmaceutical Society of Serbia hosted laboratory experts among whom the most active were Prof. Dr. Aleksandar Damanski for bromatology, Prof. Dr. Momcilo Mokranjac for toxicology and Docent Dr. Pavle Trpinac for biochemistry. When the Managing Board of the Pharmaceutical Society of National Republic of Serbia held its session on 22 December 1950, an issue was raised with reference to creation of a Section that would gather together the laboratory experts. Section for Sanitary Chemistry, combining all three profiles of laboratory staff, i.e. medical biochemists, sanitary chemists and toxicologists, was founded on 1st of January 1951. On 15 May 1955, during the sixth plenum of the Society of Pharmaceutical Societies of Yugoslavia (SFRY) held in Split, the decision was passed to set up a Section for Medical Biochemistry in SFDJ. The Section for Medical Biochemistry in SFDJ was renamed into Society for Medical Biochemistry of SFDJ based on the decision passed during the 16th plenum of SFDJ, held on 15 May 1965 in Banja Luka. Pursuant to the decision passed by SMBY on 6 April 1995 and based on the historic data, 15 May was declared as being the official Day of the Society of Medical Biochemists of Yugoslavia. The purpose of YuSMB (currently SMBSCG) is to gather medical biochemists who would develop and enhance all the branches of medical biochemistry in health industry. Its tasks are as following: to standardize operations in clinical-biochemical laboratories, education of young biochemists on all levels, encouraging scientific research, setting up of working norms and implementation, execution and abiding by the ethics codices with health workers. SMBSCG is to promote the systemized standards in the field of medical biochemistry with the relevant federal and republican institutions. SMBSCG is to enable exchange of experiences of its members with the members of affiliate associations in the country and abroad. .
APA, Harvard, Vancouver, ISO, and other styles
4

Fartushok, Tetiana V., Nadiia V. Fartushok, Yu M. Fedevych, and Vladyslav V. Pyndus. "HISTORY OF BIOCHEMISTRY IN LVIV." Wiadomości Lekarskie 75, no. 4 (2022): 881–90. http://dx.doi.org/10.36740/wlek202204124.

Full text
Abstract:
The aim: The purpose of this literature review is to shed light on the development of biochemical knowledge in the Lviv region and on prominent figures in the development of biochemistry during the Second World War. Materials and methods: Review of literature published before 2020. We searched the literature using the search terms ‘biochemists’, ‘ Lviv National Medical University’, ‘second World War’. Conclusions: The development of biological research in Lviv can be divided into two historical stages: 1) from the beginning of the founding of Lviv University in 1661 to the First World War; 2) between the First and Second World Wars and after the Second World War. Biochemical research was initiated at the Medical Faculty of Lviv University. In 1939, the Lviv State Medical Institute was established on the basis of the Medical Faculty of the University, where a powerful department of biochemistry functioned, which was headed by a worldclass biochemist – Jakub Parnas.
APA, Harvard, Vancouver, ISO, and other styles
5

Jia, Jun. "Teaching Reform and Practice Exploration of Medical Biochemistry Theory Course." Lifelong Education 9, no. 6 (September 28, 2020): 60. http://dx.doi.org/10.18282/le.v9i6.1298.

Full text
Abstract:
Biochemists lack understanding of professional medical knowledge, and clinicians have very little understanding of biochemistry, which makes it difficult to teach medical biochemistry theory. However, with the rapid development of life sciences, the demand for high-quality medical personnel in today’s society has also become higher and higher. Therefore, it is necessary to link biochemistry with medicine, and at the same time learn from the teaching concepts of biochemistry, to explore several ways to improve the teaching quality of medical biochemistry theory courses.
APA, Harvard, Vancouver, ISO, and other styles
6

Gevers, Wieland. "Medical biochemistry." Biochemical Education 21, no. 2 (April 1993): 109. http://dx.doi.org/10.1016/0307-4412(93)90064-7.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

DUGGAN, P. FINBARR, and COLIN A. ROSS. "Teaching biochemistry and medical biochemistry to medical students." Biochemical Society Transactions 14, no. 2 (April 1, 1986): 467. http://dx.doi.org/10.1042/bst0140467.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Milosevic Georgiev, Andrijana, Dušanka Krajnović, Jelena Manojlović, Svetlana Ignatović, and Nada Majkić Singh. "Seventy Years of Biochemical Subjects’ Development in Pharmacy Curricula: Experience from Serbia/ Sedamdeset godina razvoja biohemijskih predmeta u kurikulumu farmacije: iskustvo iz srbije." Journal of Medical Biochemistry 35, no. 1 (January 1, 2016): 69–79. http://dx.doi.org/10.1515/jomb-2015-0018.

Full text
Abstract:
Summary Introduction: The pharmacists played an important role in the development of biochemistry as applied chemistry in Serbia. What is more, the first seven state chemists in Ser bia were pharmacists. State chemists performed the chemicaltoxicological analysis as well as some medical and biochemical ones. When it comes to the education of medical biochemists as health workers, the period after the beginning of the second half of the twentieth century should be taken into account because that is when the training of pharmaceutical staff of the Faculty of Pharmacy, University of Belgrade, begins on the territory of Serbia. This paper presents the development of medical biochemistry through the development of curriculum, personnel and literature since the foundation of the Faculty of Pharmacy in Serbia until today. Objective: The aim of this paper is to present the historical development of biochemistry at the Faculty of Pharmacy, University of Belgrade, through analysis of three indicators: undergraduate and postgraduate education of medical biochemists, teaching literature and professional associations and trade associations. Method: The method of direct data was applied in this paper. Also, desktop analysis was used for analyzing of secondary data, regulations, curricula, documents and bibliographic material. Desktop research was conducted and based on the following sources: Archives of the University of Belgrade- Faculty of Pharmacy, Museum of the History of Pharmacy at the University of Belgrade-Faculty of Pharmacy, the Society of Medical Biochemists of Serbia and the Serbian Chamber of Biochemists. Results and conclusion: The curricula, the Bologna process of improving education, the expansion of the range of subjects, the number of students, professional literature for teaching biochemistry, as well as professional associations and trade associations are presented through the results.
APA, Harvard, Vancouver, ISO, and other styles
9

Vella, F. "Molecular Medical Biochemistry." Biochemical Education 19, no. 1 (January 1991): 43. http://dx.doi.org/10.1016/0307-4412(91)90158-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Taylor, Frances. "Molecular medical biochemistry." Trends in Biochemical Sciences 15, no. 10 (October 1990): 404. http://dx.doi.org/10.1016/0968-0004(90)90249-b.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Medical Biochemistry"

1

Woodhouse, Jennifer Ann. "Plutonium pharmacokinetics and blood biochemistry." Thesis, University of Central Lancashire, 1997. http://clok.uclan.ac.uk/20148/.

Full text
Abstract:
Since its discovery in the early 1940s the element plutonium has been seen by mankind as both an opportunity and a threat. As a radioactive nuclide plutonium presents health hazards in its handling and if mankind is to make the most of this element's potential benefits it is essential that these hazards be understood. Both overestimation and underestimation of these hazards are damaging to its proper utilisation. Many studies have been carried out to determine the effects of plutonium exposure and a broad picture of the biological behaviour of plutonium has been built up. Radiological protection standards are based on such broad understanding and a "Central Dogma" has arisen viz, plutonium is bound avidly in liver and bone; clearance half-lives from these organs differ (by a factor of 2.5) but are very long - a minimum of 50 years for bone; this is why plutonium urinary excretion levels are very low. Despite all the research work that has been carried out there are many important areas of plutonium behaviour which are not well understood or in which the central ideas adopted for radiological protection purposes are questionable. One such questionable area is extended half-life in the body. Two rather different areas relate to the molecular binding interactions which plutonium enters into in body tissues and transfer mechanisms from blood into cellular organelles. Very little is known about these processes and the speciation that plutonium demonstrates within the body. This thesis explores understanding of plutonium behaviour by application of pharmacokinetic theory to observed human behaviour, both following occupational exposure and experimental injection. Occupational exposure data demonstrated behaviour consistent with pharmacokinetic expectations over periods of 25 years or more. Long-term half-lives were 10 to 30 years rather than 50 to 100 years or more. There was no evidence of differing half-lives between liver and bone. Very low renal clearance was seen in intravenous injection studies suggesting either very extensive plutonium binding to the protein transferrin in blood or pointing to reabsorption in the kidney tubule after glomerular filtration. This latter possibility might lead to a "Plutonium blood pressure" which effectively forces activity into tissues irrespective of the strength of binding forces. Experimental work indicated species differences in transferrin binding which may have relevance for extrapolation from animals to humans.
APA, Harvard, Vancouver, ISO, and other styles
2

Zhong, Sheng-Ping. "Biodegradation of medical polymers." Thesis, University of Liverpool, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333769.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Schrift, Greta Lynn. "Energetic consequences of structural features and dynamics changes upon nucleotide binding to ribonuclease SA molecular basis for nucleotide binding specificity /." Diss., University of Iowa, 2004. http://ir.uiowa.edu/etd/120.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Driver, Cathryn Helena Stanford. "The development of a radiolabelled macromolecule as a therapeutic agent for the treatment of cancer." Doctoral thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15540.

Full text
Abstract:
One of the major focus areas of anticancer therapy is the design of new radiotherapeutic agents that are able to specifically target and destroy cancer cells with minimal side effects and damage to healthy, normal cells. This thesis describes studies towards the synthesis of a macromolecular bioconjugate that was designed to: i) co-ordinate a radioisotope through a tetra-amine macrocycle (cyclam), ii) lead to passive tumour targeting via the EPR effect and a suitably large carrier such as human serum albumin and iii) induce active targeting through a glucose moiety recognised by the over-expressed glucose transporters on the surface of highly metabolically active cancer cells. The various cyclam functionalisation strategies explored were relatively unsuccessful, but eventually a bis-aminal cyclam was successfully converted, through nucleophilic substitution, into a precursor pro-conjugate: a di-functionalised cyclam containing a β-glycoside tether and a long chain primary alkylamine. The glycoside tether was synthesised via glycosylation of a glycosyl iodide with decandiol followed by oxidation of the terminal hydroxyl group to an acid chloride for cyclam acylation. The second linker attached to cyclam was synthesised by conversion of decanediol to a brominated alkyl amine. This amine would then be converted into a maleimide functionality suitable for Michael addition with a free thiol group contained within the proposed bio-carrier to form the desired bioconjugate. Further studies described towards the synthetic construction of the bioconjugate include: 1) The construction of a maleimide group 2) The attachment of an imaging radioisotope, ⠹⠹m Tc, or therapeutic isotope, ¹⠰³ Pd, to the pro- conjugate and other glucose-cyclam precursors 3) The determination of the potential uptake of the bioconjugate through glucose transporters by using a fluorescent dansyl-glucose compound as a model and monitoring its uptake into WHCO1 oesophageal cancer cells. 4) The HPLC analysis of the coupling of a glucose-maleimide model compound to bovine serum albumin to investigate the Michael addition of the free thiol in HSA to a maleimide 5) The development of a potentially alternative nanoparticle carrier by synthesis of palladium and magnetic nanoparticles with commercially available thioglucose or glucuronic acid moieties as the surface targeting and stabilising agent. In summary, this thesis outlines a number of synthetic, radiological and biological aspects towards the development of a fully functioning radiolabelled macromolecular bioconjugate that could be tested for improved targeted cancer radiotherapy.
APA, Harvard, Vancouver, ISO, and other styles
5

Viljoen, Katie S. "Integrative genomic analyses of bacterially-associated colorectal cancer." Doctoral thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15761.

Full text
Abstract:
Sporadic colorectal cancer (CRC) has been linked to various lifestyle factors, including the consumption of alcohol and red meat, smoking, and obesity. CRC is one of most extensively characterised cancers, both at a molecular and 'omic' level; nevertheless, the precise mechanism driving CRC initiation remains unknown. To date, numerous studies have identified changes in the microbial profiles of CRCs compared to adjacent normal mucosa and compared to healthy controls; however, CRC-associated bacteria have not been concurrently quantified across a single cohort; nor have the relationships between CRC-associated bacteria, clinicopathological features of CRC and genomic subtypes of CRC been investigated. The main aim of this thesis was therefore to gain insight into the potential contribution of CRC-associated bacteria in the aetiopathogenesis of CRC by leveraging both host genomic and clinicopathological data as well as to investigate patterns of tissue colonisation between different CRC-associated bacteria. The objectives were 1) to quantify, using quantitative-PCR, CRC-associated bacteria in a cohort of 55 paired tumour and adjacent histologically normal samples collected during surgical resection as well as in an additional 18 formalin-fixed paraffin-embedded (FFPE) samples; 2) to determine their relationships to patient age, gender, ethnicity, stage of disease, site of disease and MSI status (Chapter 4); 3) to evaluate the relationship between each bacterium and host gene expression (Chapter 8) and methylation changes (Chapter 6); and 4) to determine genomic subtypes of CRC using unsupervised clustering of gene expression data in the context of patient clinicopathological features and bacterial quantitation data; and 5) to gain a deeper biological understanding of the results from the objectives 1–4 using pathway analyses of the genomic subtypes obtained (Chapter 7). The main finding of this thesis is that a transcriptomic subtype of colorectal cancer, characterised by an increase in CpG island methylation, displays an increased frequency of colonisation by Enterococcus faecalis and by high levels of Fusobacterium. At the pathway-level, this subtype is enriched for pathways related to damage response, infection, inflammation and cellular proliferation; notably, these findings were confirmed in a well-defined publically available CRC gene expression dataset of colorectal adenocarcinomas (N=155). These findings suggest that specific bacterial colonisation underlie s a distinct genomic subtype of colorectal cancer that is characterise d by inflammatory-related gene expression changes ; these findings however require validation in a larger cohort. In addition, novel associations between colonisation by specific bacteria and host clinicopathological, transcriptomic and DNA methylation features were identified.
APA, Harvard, Vancouver, ISO, and other styles
6

Esau, Luke Emmanuel. "Proliferative and survival pathways in oesophageal cancer." Doctoral thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/12279.

Full text
Abstract:
Includes abstract.
Includes bibliographical references.
Oesophageal squamous cell carcinoma (OSCC) is the 8th most common cancer worldwide with high incidence in areas that include China, Iran and South Africa. The current treatment available for OSCC does not significantly enhance patient survival. A better understanding of proliferative and survival pathways activated in OSCC could allow identification of more specific therapeutic targets, potentially improving management of OSCC. Cell surface receptors are known to play important roles in relaying signals from the extracellular environment...The aim of this study was to determine the role of EGFR, IGF-1R and CXCR2 in proliferation and survival of OSCC cells.
APA, Harvard, Vancouver, ISO, and other styles
7

Gordon, Kerry. "Protein-protein interactions of human somatic angiotensin-converting enzyme." Doctoral thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/10535.

Full text
Abstract:
In this study, novel disulphide bridges were engineered into the linker region of ACE [Angiotensin-converting enzyme] in an attempt to limit inter-domain movement, thereby producing a candidate for crystallisation and to determine the effect of these bridges on inter-domain movement.
APA, Harvard, Vancouver, ISO, and other styles
8

Matejcic, Marco. "Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa." Doctoral thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3139.

Full text
Abstract:
Includes abstract.
Includes bibliographical references.
Oesophageal squamous cell carcinoma (OSCC) is a complex disease, determined by the interaction of genetic factors with environmental risk factors. In South Africa, OSCC is a major malignancy occurring with high incidence in the Black and Mixed Ancestry populations. Previous studies by our research group have reported that genetic polymorphism of xenobiotic metabolizing enzymes influence greatly the detoxification of tobacco-related carcinogens in vivo, and may therefore have an important role in determining susceptibility to oesophageal cancer.
APA, Harvard, Vancouver, ISO, and other styles
9

Parker, Ayesha. "The characterisation of the ectodomain shedding of the low density lipoprotein receptor." Doctoral thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/3145.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Ronacher, Katharina. "Internalisation of the type II gonadotropin-releasing hormone receptor of marmoset monkey." Doctoral thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/8599.

Full text
Abstract:
Bibliography: leaves 102-124.
The mammalian type II GnRH receptor has a C-terminal tail unlike the mammalian type I GnRH receptor, which uniquely lacks the cytoptasmic C- terminal domain. lnternalisation of a mammalian type ll GnRH receptor has never been investigated, therefore this thesis studies the internalisation pathway of the type ll GnRH receptor. As the C-terminal tail mediates rapid internalisation of many G protein-coupled receptors this research investigates the functional role of the C-terminal tail and intracellular loop in receptor internalisation. The internalisation pathway of the type ll GnRH receptor in COS-1 cells was investigated by co expressing dominant negative mutants and wild- type constructs of G protein-coupled receptor kinases (GRKs), dynamin-1 and β-arrestin 1 and 2 with the type II GnRH receptor. The results show that internatisation of the receptor requires GRK 2 and dynamin but does not require β-arrestin 1 and 2. Furthermore, inhibitors to both the caveolae pathway as well as the clathrin coated vesicle endocytosis abolished receptor internalisation indicating that both structures are involved in internalisation of the receptor. Even though in COS-1 cells the type ll GnRH receptor internatises in a β-arrestin independent manner, internalisation of this receptor can be enhanced by over-expression of wild type β-arrestin. This indicates that the type ll GnRH receptor is able to utilise a β-arrestin mediated internaltsation pathway if high levels of β-arrestin are present in the cell. The mammalian type ll GnRH receptor internalises with enhanced rate and extent compared to the tail-less human type I GHRH receptor. The role of the C-terminal tail of the type ll GnRH receptor in internalisation was investigated by measuring internalisation of C-terminally truncated mutants. It was found that the region between Gly 343 and Ser 335 within the C-terminal domain is important for receptor internalisation. Substitution of putative phosphorylation sites within this region revealed that Ser 338 and Ser 339 are critical for rapid receptor internalisation. Furthermore a serine residue in intracellular loop three (Ser 251) was shown to play a role in signalling as well as in internalisation. Since dominant negative GRK 2 could not inhibit internalisation of a mutant lacking all three serine residues, but could reduce internalisation of the wild-type receptor, we suggest that Ser 251, 338 and 339 are target of phosphorylation by GRK. However these phosphorylation sites as well as the C-terminal tail are not necessary for β-arrestin dependent internalisation. Taken together this thesis elucidates the internalisation pathway of a mammalian type lI GnRH receptor and identified residues within the C-terminal tail and intracellular loop three that are critical for rapid internalisation.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Medical Biochemistry"

1

Rao, N. Mallikarjuna. Medical biochemistry. 2nd ed. New Delhi: New Age International (P) Ltd., Publishers, 2006.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

J, Thompson R., ed. Molecular medical biochemistry. Cambridge [England]: Cambridge University Press, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

R, Ferrier Denise, ed. Biochemistry. 5th ed. Philadelphia: Health, 2010.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Meisenberg, Gerhard. Principles of medical biochemistry. 2nd ed. St. Louis: Mosby, 2006.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Simmons, William H., Ph. D., ed. Principles of medical biochemistry. St. Louis: Mosby, 1998.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Lieberman, M. A. Marks' essential medical biochemistry. Philadelphia: Lippincott Williams & Wilkins, 2007.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

D, Marks Allan, Smith Colleen M, Marks Dawn B, and Smith Colleen M, eds. Marks' essential medical biochemistry. Baltimore, MD: Lippincott Williams & Wilkins, 2006.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Chatterjea, M. N. Textbook of medical biochemistry. 8th ed. New Delhi: Jaypee Brothers Medical Publications (P) Ltd., 2012.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Simmons, William H., Ph. D., ed. Principles of medical biochemistry. 3rd ed. Philadelphia: Elsevier/Saunders, 2012.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

A, Harvey Richard, ed. Biochemistry. Philadelphia: J.B. Lippincott, 1994.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Medical Biochemistry"

1

Mitchell, Graham. "CELL BIOCHEMISTRY." In Medical Physiology, 3–19. Elsevier, 1986. http://dx.doi.org/10.1016/b978-0-409-10727-2.50007-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

BHAGAVAN, N. V. "Biochemistry of Hemostasis." In Medical Biochemistry, 839–72. Elsevier, 2002. http://dx.doi.org/10.1016/b978-012095440-7/50038-x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Ramakrishnan, S., and KN Sulochana. "Biochemistry." In Manual of Medical Laboratory Techniques, 1. Jaypee Brothers Medical Publishers (P) Ltd., 2012. http://dx.doi.org/10.5005/jp/books/11559_1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Chatterjea, MN, and Rana Shinde. "Environmental Biochemistry." In Textbook of Medical Biochemistry, 780. Jaypee Brothers Medical Publishers (P) Ltd., 2012. http://dx.doi.org/10.5005/jp/books/11486_45.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Chatterjea, Dr, and Dr Shinde. "Environmental Biochemistry." In Textbook of Medical Biochemistry, 723. Jaypee Brothers Medical Publishers (P) Ltd., 2007. http://dx.doi.org/10.5005/jp/books/10917_45.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Raman, PG, and LC Gupta. "Blood Biochemistry." In Manual of Medical Emergencies, 318. Jaypee Brothers Medical Publishers (P) Ltd., 2001. http://dx.doi.org/10.5005/jp/books/11606_58.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

"Front Matter." In Medical Biochemistry, iii. Elsevier, 2002. http://dx.doi.org/10.1016/b978-0-12-095440-7.50052-4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

"Copyright." In Medical Biochemistry, iv. Elsevier, 2002. http://dx.doi.org/10.1016/b978-0-12-095440-7.50053-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Baynes, J. W., and M. H. Dominiczak. "Introduction." In Medical Biochemistry, 1–4. Elsevier, 2009. http://dx.doi.org/10.1016/b978-0-323-05371-6.00001-2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Taniguchi, N. "Amino Acids and Proteins." In Medical Biochemistry, 5–21. Elsevier, 2009. http://dx.doi.org/10.1016/b978-0-323-05371-6.00002-4.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Medical Biochemistry"

1

"Standardizing Biochemistry Dataset for Medical Research." In International Conference on Health Informatics. SCITEPRESS - Science and and Technology Publications, 2014. http://dx.doi.org/10.5220/0004745802050210.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Ismail, Noor Akmal Shareela, Khaizurin Tajul Arifin, Ekram Alias, Jen Kit Tan, Mohd Hanafi Ahmad Damanhuri, Norwahidah Abdul Karim, Jo Aan Goon, Zakiah Jubri Mohd Zubri, Suzana Makpol, and Yasmin Anum Mohd Yusof. "LEARNING MEDICAL BIOCHEMISTRY THROUGH INTERACTIVE LEARNING." In 10th International Conference on Education and New Learning Technologies. IATED, 2018. http://dx.doi.org/10.21125/edulearn.2018.0966.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Ilaslaner, Tacnur, and Aysegul Guven. "Investigation of the Effects Biochemistry on Iron Deficiency Anemia." In 2019 Medical Technologies Congress (TIPTEKNO). IEEE, 2019. http://dx.doi.org/10.1109/tiptekno.2019.8895227.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Monova, Tanya, Oleg Konstantinov, Sylvia Kalenderova, Stefan Tsakovski, and Ganka Kossekova. "Design and implementation of virtual models in medical biochemistry learning." In PROCEEDINGS OF THE 44TH INTERNATIONAL CONFERENCE ON APPLICATIONS OF MATHEMATICS IN ENGINEERING AND ECONOMICS: (AMEE’18). Author(s), 2018. http://dx.doi.org/10.1063/1.5082051.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Alias, Ekram, and Noor Akmal Shareela Ismail. "SYNCHRONOUS LECTURES: IS IT APPEALING FOR MEDICAL STUDENTS TO LEARN BIOCHEMISTRY?" In 15th International Technology, Education and Development Conference. IATED, 2021. http://dx.doi.org/10.21125/inted.2021.0774.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Kaksis, Aris, Agnese Brangule, and Mihails Halitovs. "AN APPROACH TO TEACHING MEDICAL CHEMISTRY THAT HIGHLIGHTS INTERDISCIPLINARY NATURE OF SCIENCE." In 1st International Baltic Symposium on Science and Technology Education. Scientia Socialis Ltd., 2015. http://dx.doi.org/10.33225/balticste/2015.54.

Full text
Abstract:
Thermodynamics is a branch of physics that deals with questions concerning energies and work of a system. It is one of the key topics for understanding processes in the universe as well as any separate system like a gas mixture or a single cell in a biological system. Thermodynamics is included in the university curriculum for engineering, chemistry and physics students as well as medical student curriculum. This paper outlines the problems faced by first year medical students learning thermodynamics at Riga Stradinš University. We describe a medically relevant context based approach to teaching that demonstrates the interdisciplinary nature of medical chemistry, molecular biology and biochemistry. Our method provides a model in which disciplinary barriers are diminished and increased effectiveness of teaching is achieved. Key words: interdisciplinary teaching, medical chemistry, thermodynamics, teaching and learning thermodynamics.
APA, Harvard, Vancouver, ISO, and other styles
7

Ukibayev, J. K., U. M. Datkhayev, A. P. Frantsev, and D. A. Myrzakozha. "Rectal Methods of Delivery of Medical Drugs of the Protein Nature." In ICBBB '20: 2020 10th International Conference on Bioscience, Biochemistry and Bioinformatics. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3386052.3386076.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Ismail, Noor Akmal Shareela. "ONLINE TEAM-BASED LEARNING: AN INNOVATION FOR REMOTE ACTIVE LEARNING IN MEDICAL BIOCHEMISTRY." In 13th International Conference on Education and New Learning Technologies. IATED, 2021. http://dx.doi.org/10.21125/edulearn.2021.0417.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Djunet, Nur Aini, Rizki Fajar Utami, and Asri Hendrawati. "Evaluation of Virtual Biochemistry Practicum on First Year Students at Faculty of Medicine Universitas Islam Indonesia." In International Conference on Medical Education (ICME 2021). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/assehr.k.210930.052.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Кіндрат, Ірина. "CLINICAL CASE BASED LEARNING AS AN INNOVATIVE METHOD FOR TEACHING BIOCHEMISTRY IN MEDICAL UNIVERSITY." In LE TENDENZE E MODELLI DI SVILUPPO DELLA RICERСHE SCIENTIFICI. European Scientific Platform, 2020. http://dx.doi.org/10.36074/13.03.2020.v2.17.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Medical Biochemistry"

1

Terah, Elena Igorevna. The work program, guidelines and evaluation materials of the discipline «Inorganic Chemistry» for students of the specialty «Medical Biochemistry». Novosibirsk State Medical University, 2020. http://dx.doi.org/10.12731/inorganicchemistry-terahelena.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Medical Biochemistry' for particular source types:
Journal articles Dissertations / Theses Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography