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Journal articles on the topic 'Medical applications potential'

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Author: Grafiati

Published: 6 September 2023

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1

El-Naggar, Moustafa Y., Amira M. Hamdan, Ehab A. Beltagy, Hassan A. H. Ibrahim, and Mahetab M. M. Moustafa. "Endotoxin Production by Pseudomonas aeruginosa ATCC 9027 with Potential Medical Applications." Journal of Pure and Applied Microbiology 13, no. 1 (March 31, 2019): 97–106. http://dx.doi.org/10.22207/jpam.13.1.10.

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Anil, Sukumaran. "Potential Medical Applications of Chitooligosaccharides." Polymers 14, no. 17 (August 29, 2022): 3558. http://dx.doi.org/10.3390/polym14173558.

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Chitooligosaccharides, also known as chitosan oligomers or chitooligomers, are made up of chitosan with a degree of polymerization (DP) that is less than 20 and an average molecular weight (MW) that is lower than 3.9 kDa. COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. This review aims to outline the recent advances and potential applications of COS in various diseases and conditions based on the available literature, mainly from preclinical research. The prospects of further in vivo studies and translational research on COS in the medical field are highlighted.

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Alric, Matthieu, Frédéric Chapelle, Jean-Jacques Lemaire, and Grigore Gogu. "Potential applications of medical and non-medical robots for neurosurgical applications." Minimally Invasive Therapy & Allied Technologies 18, no. 4 (January 2009): 193–216. http://dx.doi.org/10.1080/13645700903053584.

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4

Reddy, Narendra, and Yiqi Yang. "Potential of plant proteins for medical applications." Trends in Biotechnology 29, no. 10 (October 2011): 490–98. http://dx.doi.org/10.1016/j.tibtech.2011.05.003.

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5

Garbacz, Halina, and Krzysztof Jan Kurzydlowski. "Properties of Nanotitanium for Potential Medical Applications." Macromolecular Symposia 253, no. 1 (August 2007): 128–33. http://dx.doi.org/10.1002/masy.200750719.

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6

Quan, Pham Hong, Veronica Manescu Paltanea, Gheorghe Paltanea, Iulian Antoniac, and Iosif Vasile Nemoianu. "Potential of Biodegradable Magnesium Alloys for Medical Applications." Key Engineering Materials 931 (September 9, 2022): 55–61. http://dx.doi.org/10.4028/p-r405h8.

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Biodegradability of magnesium alloys in physiological media is important for material use in implant manufacture industry. Two industrial Mg alloys ZQ71 and ZQ63 were investigated. Optical microscopy was used to put in evidence microstructure. The conclusions are correlated with obtained results after scanning electron microscopy investigations coupled with energy dispersive X-ray spectroscopy. The evaluation of the hydrogen released rate was analyzed in laboratory made simulated body fluid (SBF) and Hanks’ solution at 37°C for 10 days. Different degradation rates are obtained, and it can be concluded that they depend on chemical composition of the alloys and on immersion time of the samples in different physiological solutions.

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7

Piskin, E. "Potential Sorbents for Medical and Some Related Applications." International Journal of Artificial Organs 9, no. 6 (November 1986): 401–4. http://dx.doi.org/10.1177/039139888600900608.

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8

Noor, Hafizh Muhammad. "Potential of Carrageenans in Foods and Medical Applications." GHMJ (Global Health Management Journal) 2, no. 2 (June 30, 2018): 32. http://dx.doi.org/10.35898/ghmj-22188.

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Background: Carrageenans, the polysaccharides obtained by extraction of certain species of red seaweeds (Rhodophyceae), have been widely used in both food industry and medical applications because of their excellent physical functional properties that are used as gelling, thickening and stabilizing agent. Several studies showed biological properties of carrageenans such as antiviral, anticoagulant, antitumor, antioxidant, anti-inflammatory and immune-modulatory activity. Aims: This study is to bring a short overview of the potential of carrageenans in foods and medical applications based on their biological activities.Methods: This short overview used relevant works and articles examined that collected through several electronic database including PubMed, Science Direct, Springer Link and Google Scholars for the years 1991-2018 with full text in English.Results: This study is an alternative approach that is necessary in order to present the potential of carrageenans in foods and medical applications.The advantages of carrageenans as a food additive and pharmaceutical formulation lie on their high availability, low cost, and low induction of resistance. Conclusion: This review suggested that carrageenans are suitable to be applied in many kinds of food products as gelling and thickening agent with their antioxidant potency as well as medical applications such as pharmaceutical formulations in drug delivery and experimental medicine. However, more comprehensive studies on toxicity and side effect of carrageenans are necessary.

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Yasmin, Rehana, Mohsin Shah, Saeed Ahmad Khan, and Roshan Ali. "Gelatin nanoparticles: a potential candidate for medical applications." Nanotechnology Reviews 6, no. 2 (April 1, 2017): 191–207. http://dx.doi.org/10.1515/ntrev-2016-0009.

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AbstractGelatin is a protein obtained from the hydrolysis of collagen. Gelatin is an attractive biodegradable material for use in nano-biotechnology and nano-pharmaceutics. Gelatin nanoparticles (NPs) have been widely used as drug and gene carrier to targeted sick tissues including cancer, tuberculosis, HIV infection along with the treatment of vasospasm and restenosis, due to its biocompatibility and biodegradability. For instance, coating with gelatin lowers the cytotoxicity of quantum dots. Moreover, gelatin NPs have the ability to cross the blood-brain barrier, hence proven as a promising candidate to target brain disorders. Macrophage targeting with gelatin NPs for remedy of different diseases is repeatedly reported in previous years. In tissue engineering gelatin is actively utilized for construction of biological and life-long 3D scaffolds for bio-artificial tissues and organ production. Gelatins have a wide range of potential applications which needs to be unraveled in more detail. This review is mainly focused on the applications of gelatin NPs in biomedical sciences.

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10

Menz, W., and A. Guber. "Microstructure Technologies and their Potential in Medical Applications." min - Minimally Invasive Neurosurgery 37, no. 01 (September 1994): 21–27. http://dx.doi.org/10.1055/s-2008-1053444.

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11

Xu, Helan, Qiuran Jiang, Narendra Reddy, and Yiqi Yang. "Hollow nanoparticles from zein for potential medical applications." Journal of Materials Chemistry 21, no. 45 (2011): 18227. http://dx.doi.org/10.1039/c1jm11163a.

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12

Amenta, Valeria, and Karin Aschberger. "Carbon nanotubes: potential medical applications and safety concerns." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 7, no. 3 (November 27, 2014): 371–86. http://dx.doi.org/10.1002/wnan.1317.

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13

McKenney, James M. "Potential Nontraditional Applications of Statins." Annals of Pharmacotherapy 37, no. 7-8 (July 2003): 1063–71. http://dx.doi.org/10.1345/aph.1c499.

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OBJECTIVE: To review the current evidence for use of hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) in nontraditional lipid-related applications, including acute coronary syndromes, peripheral arterial disease, stroke, and renal disease, and to describe ongoing trials evaluating the role of statins in these conditions. DATA SOURCES: Clinical literature was identified by a MEDLINE search (1990–November 2002) using ≥1 of the following search terms: acute coronary syndrome(s), angina pectoris, atherosclerosis, atorvastatin, clinical trials, diabetes mellitus, end-stage renal disease, fluvastatin, lovastatin, myocardial infarction, peripheral arterial disease, pravastatin, simvastatin, statins, and stroke. Treatment guidelines issued by professional and governmental organizations, such as the American Diabetes Association, American Heart Association, National Cholesterol Education Program, National Kidney Foundation, and National Stroke Foundation, were reviewed. STUDY SELECTION AND DATA EXTRACTION: Articles identified from the data sources were included if they pertained to the conditions described in the objectives and provided unique information concerning use of statins. DATA SYNTHESIS: Substantial evidence exists for the use of statins in acute coronary syndromes. Meta-analyses of data from major clinical trials indicate that statins prevent first and recurrent stroke, and large-scale trials are underway to evaluate the efficacy of statins in this setting. Accumulating evidence suggests that statins may be beneficial in reducing the morbidity and mortality associated with peripheral arterial disease and end-stage renal disease, and results from ongoing trials may confirm these benefits. Statins may also have a future role in amelioration of other conditions associated with atherosclerosis, such as diabetes mellitus. CONCLUSIONS: A large body of evidence supports the evaluation of statins in clinical settings beyond primary and secondary prevention of morbidity and mortality associated with coronary atherosclerosis.

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14

Pomin, Vitor H., William P. Vignovich, Alysia V. Gonzales, Ariana A. Vasconcelos, and Barbara Mulloy. "Galactosaminoglycans: Medical Applications and Drawbacks." Molecules 24, no. 15 (August 1, 2019): 2803. http://dx.doi.org/10.3390/molecules24152803.

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Galactosaminoglycans (GalAGs) are sulfated glycans composed of alternating N-acetylgalactosamine and uronic acid units. Uronic acid epimerization, sulfation patterns and fucosylation are modifications observed on these molecules. GalAGs have been extensively studied and exploited because of their multiple biomedical functions. Chondroitin sulfates (CSs), the main representative family of GalAGs, have been used in alternative therapy of joint pain/inflammation and osteoarthritis. The relatively novel fucosylated chondroitin sulfate (FCS), commonly found in sea cucumbers, has been screened in multiple systems in addition to its widely studied anticoagulant action. Biomedical properties of GalAGs are directly dependent on the sugar composition, presence or lack of fucose branches, as well as sulfation patterns. Although research interest in GalAGs has increased considerably over the three last decades, perhaps motivated by the parallel progress of glycomics, serious questions concerning the effectiveness and potential side effects of GalAGs have recently been raised. Doubts have centered particularly on the beneficial functions of CS-based therapeutic supplements and the potential harmful effects of FCS as similarly observed for oversulfated chondroitin sulfate, as a contaminant of heparin. Unexpected components were also detected in CS-based pharmaceutical preparations. This review therefore aims to offer a discussion on (1) the current and potential therapeutic applications of GalAGs, including those of unique features extracted from marine sources, and (2) the potential drawbacks of this class of molecules when applied to medicine.

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15

Ashammakhi, N. "Nanosize, Mega-Impact, Potential for Medical Applications of Nanotechnology." Journal of Craniofacial Surgery 17, no. 1 (January 2006): 3–7. http://dx.doi.org/10.1097/01.scs.0000201086.73166.f0.

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16

Waynant, R. W., and I. K. Ilev. "Toward practical coherent X-ray sources: potential medical applications." IEEE Journal of Selected Topics in Quantum Electronics 6, no. 6 (November 2000): 1465–69. http://dx.doi.org/10.1109/2944.902202.

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17

Dudkowiak, Alina, Ewa Teślak, and Jan Habdas. "Photophysical studies of tetratolylporphyrin photosensitizers for potential medical applications." Journal of Molecular Structure 792-793 (July 2006): 93–98. http://dx.doi.org/10.1016/j.molstruc.2005.12.052.

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18

Roukos, Dimitrios H. "Next-generation sequencing and epigenome technologies: potential medical applications." Expert Review of Medical Devices 7, no. 6 (November 2010): 723–26. http://dx.doi.org/10.1586/erd.10.68.

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19

Pop, Bogdan, Bogdan Fetica, Mihaiela Luminita Blaga, Adrian Pavel Trifa, Patriciu Achimas-Cadariu, Catalin Ioan Vlad, and Andrei Achimas-Cadariu. "The role of medical registries, potential applications and limitations." Medicine and Pharmacy Reports 92, no. 1 (January 27, 2019): 7–14. http://dx.doi.org/10.15386/cjmed-1015.

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Medical registries provide highly reliable data, challenged hierarchically only by randomized controlled trials. Although registries have been used in several fields of medicine for more than a century and a half, their key role is frequently overlooked and poorly recognized. Medical registries have evolved from calculating basic epidemiological data (incidence, prevalence, mortality) to diverse applications in disease prevention, early diagnosis and screening programs, treatment response, health care planning, decision making and disease control programs. Implementing, maintaining and running a medical registry requires substantial effort. Developing the registry represents a complex task and is one of the major barriers in widespread use of registries. Medical registries have potential to evolve to a next generation by taking benefit from recent semantic web technology developments. This paper is aimed at providing a summary of the basic information available on medical registries and to highlight the progress and potential applications in this field.

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20

Gechev, Tsanko S., Jacques Hille, Herman J. Woerdenbag, Maria Benina, Nikolay Mehterov, Valentina Toneva, Alisdair R. Fernie, and Bernd Mueller-Roeber. "Natural products from resurrection plants: Potential for medical applications." Biotechnology Advances 32, no. 6 (November 2014): 1091–101. http://dx.doi.org/10.1016/j.biotechadv.2014.03.005.

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21

Raffort, Juliette, Charlotte Hinault, Olivier Dumortier, and Emmanuel Van Obberghen. "Circulating microRNAs and diabetes: potential applications in medical practice." Diabetologia 58, no. 9 (July 9, 2015): 1978–92. http://dx.doi.org/10.1007/s00125-015-3680-y.

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22

Ubaidillah, Saiful Amri Mazlan, Joko Sutrisno, and Hairi Zamzuri. "Potential Applications of Magnetorheological Elastomers." Applied Mechanics and Materials 663 (October 2014): 695–99. http://dx.doi.org/10.4028/www.scientific.net/amm.663.695.

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Magnetorheological elastomer still becomes interested topics among researchers since the rheological properties can be controlled by applying external magnetic field by means of adjustable modulus of elasticity. In this paper, the current application of MRE and related patents will be discussed. Potential application of MRE focused on three main areas. The first is explanation on MRE implementation in vibration cancellation mainly in vehicle system such as active vibration suppression and variable impedance sound absorber. The second explanationfocuses on its potential application on medical devices such as prosthetic device. The third section describes future possible application of MRE based on its tunable properties.Finally, the concluding remarks can be generally stated that MRE still has wide range smart device development and promising more valuable product.

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23

Rodrigues, Lígia, Ibrahim M. Banat, José Teixeira, and Rosário Oliveira. "Biosurfactants: potential applications in medicine." Journal of Antimicrobial Chemotherapy 57, no. 4 (February 9, 2006): 609–18. http://dx.doi.org/10.1093/jac/dkl024.

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24

Gomez, Catherine, Gauthier Hallot, Sophie Laurent, and Marc Port. "Medical Applications of Metallic Bismuth Nanoparticles." Pharmaceutics 13, no. 11 (October 26, 2021): 1793. http://dx.doi.org/10.3390/pharmaceutics13111793.

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Recent reviews described the efficient syntheses of metallic bismuth nanoparticles. Nevertheless, few studies have been published on the medical applications of these nanoparticles compared to the number of studies on the well-documented clinical use of the bismuth(III) complex. An analysis of the literature revealed the significant potential of metallic bismuth nanoparticles in different theranostic applications. In the diagnostic field, preclinical proofs of concept have been demonstrated for X-ray, photoacoustic and fluorescence imaging. In the therapeutic field, several preclinical studies have shown the potential of bismuth nanoparticles as X-ray radiosensitizers for use in radiotherapy and as photothermal agents for applications in near infrared phototherapy. The properties of these metallic bismuth nanoparticles as bactericidal, fungicidal, antiparasitic and antibiofilm agents have also been studied. Although information concerning the toxic effects of these nanoparticles has been collected, these data are insufficient when considering the immediate clinical use of these new nanoparticles.

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25

Thomas, Christy, and Cecilia Giulivi. "Saliva protein profiling for subject identification and potential medical applications." Medicine in Omics 3 (December 2021): 100012. http://dx.doi.org/10.1016/j.meomic.2021.100012.

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26

Malm, Johan, Mathias Farnegardh, Gary Grover, and Paul Ladenson. "Thyroid Hormone Antagonists: Potential Medical Applications and Structure Activity Relationships." Current Medicinal Chemistry 16, no. 25 (September 1, 2009): 3258–66. http://dx.doi.org/10.2174/092986709788803277.

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27

Zakrzewska, Malgorzata, Ewa Marcinkowska, and Antoni Wiedlocha. "FGF-1: From Biology Through Engineering to Potential Medical Applications." Critical Reviews in Clinical Laboratory Sciences 45, no. 1 (January 2008): 91–135. http://dx.doi.org/10.1080/10408360701713120.

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28

Bremer, Christoph, Vasilis Ntziachristos, and Ralph Weissleder. "Optical-based molecular imaging: contrast agents and potential medical applications." European Radiology 13, no. 2 (February 2003): 231–43. http://dx.doi.org/10.1007/s00330-002-1610-0.

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29

Mahapatra, Indrani, J. Clark, Peter J. Dobson, Richard Owen, and Jamie R. Lead. "Potential environmental implications of nano-enabled medical applications: critical review." Environ. Sci.: Processes Impacts 15, no. 1 (2013): 123–44. http://dx.doi.org/10.1039/c2em30640a.

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30

Karakuła-Juchnowicz, Hanna, Joanna Róg, Dariusz Juchnowicz, and Justyna Morylowska-Topolska. "GPR120: Mechanism of action, role and potential for medical applications." Postępy Higieny i Medycyny Doświadczalnej 71 (November 19, 2017): 0. http://dx.doi.org/10.5604/01.3001.0010.5809.

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G protein-coupled receptors (GPCRs) constitute a family of transmembrane proteins that mediate many cellular processes. GPR120/FFAR4, a receptor from this family that is activated by fatty acids, has received considerable attention recently. This paper presents a literature review concerning the role of GPR120 and its mechanism of action in animal and human studies as well as the potential use of GPR120 for the treatment of chronic diseases. Two electronic databases – Medline and Google Scholar – were searched for available studies addressing the review topic that were written in English and published from 2000 to June 2017. The following key terms were used in the search: GPR120, FFA4, GPR120 agonist, PUFAs, EPA, DHA, adipocyte, obesity, hyperlipidemia, inflammation, cancer, diabetes, insulin resistance, taste, atherogenesis, hepatis, central nervous system. In humans, GPR120 expression is expressed in macrophages, eosinophils, and adipose tissue, in cells of the tongue, liver, lungs, small and large intestine, gastric mucosa, and pancreas, in the central nervous system and placental microvilli. Medium- and long-chain fatty acids act as ligands for the receptor. Through the internalization of beta-arrestin-2 complex and the inhibition of NF-κB, GPR120 mediates the activation of the cell’s anti-inflammatory mechanisms. The receptor is also involved in the maturation of adipocytes, the modulation of insulin signalling pathways, the regulation of glucose metabolism, and the secretion of intestinal hormones. GPR120 is a promising target for the treatment of numerous diseases, whose pathophysiology is associated with low-grade inflammation. As a result of intensive searches, a likely group of synthetic agonists of the receptor was determined with potential therapeutic applications in conditions such as obesity, impaired carbohydrate metabolism, inflammatory bowel diseases, cancer, mental disorders.

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31

Maldonado, Rafael, and Marta Torrens. "Cannabis research: Risks of recreational use and potential medical applications." European Neuropsychopharmacology 36 (July 2020): 167–68. http://dx.doi.org/10.1016/j.euroneuro.2020.06.009.

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32

Hodyra, Katarzyna, and Krystyna Dąbrowska. "Molecular and Chemical Engineering of Bacteriophages for Potential Medical Applications." Archivum Immunologiae et Therapiae Experimentalis 63, no. 2 (July 22, 2014): 117–27. http://dx.doi.org/10.1007/s00005-014-0305-y.

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33

Salmond, George. "Bacteriophage applications: current and potential applications in biotechnology, agriculture and medicine." Future Microbiology 1, no. 2 (August 2006): 171–73. http://dx.doi.org/10.2217/17460913.1.2.171.

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34

Uesaka, Mitsuru, and Kazuyoshi Koyama. "Advanced Accelerators for Medical Applications." Reviews of Accelerator Science and Technology 09 (January 2016): 235–60. http://dx.doi.org/10.1142/s1793626816300115.

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We review advanced accelerators for medical applications with respect to the following key technologies: (i) higher RF electron linear accelerator (hereafter “linac”); (ii) optimization of alignment for the proton linac, cyclotron and synchrotron; (iii) superconducting magnet; (iv) laser technology. Advanced accelerators for medical applications are categorized into two groups. The first group consists of compact medical linacs with high RF, cyclotrons and synchrotrons downsized by optimization of alignment and superconducting magnets. The second group comprises laser-based acceleration systems aimed of medical applications in the future. Laser plasma electron/ion accelerating systems for cancer therapy and laser dielectric accelerating systems for radiation biology are mentioned. Since the second group has important potential for a compact system, the current status of the established energy and intensity and of the required stability are given.

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35

Błaszczyk, Urszula, and Kamila Dąbrowska. "CHARACTERISTICS AND POTENTIAL APPLICATIONS OF CIRCULAR BACTERIOCINS." Postępy Mikrobiologii - Advancements of Microbiology 56, no. 4 (2019): 451–64. http://dx.doi.org/10.21307/pm-2017.56.4.451.

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36

Arthur, Timothy D., Veronica L. Cavera, and Michael L. Chikindas. "On bacteriocin delivery systems and potential applications." Future Microbiology 9, no. 2 (February 2014): 235–48. http://dx.doi.org/10.2217/fmb.13.148.

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37

KIRWAN, JOHN R. "THE POTENTIAL OF COMPUTER APPLICATIONS IN RHEUMATOLOGY." Rheumatology 26, no. 1 (1987): 3–4. http://dx.doi.org/10.1093/rheumatology/26.1.3.

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38

Walls, Elizabeth V., and Dorothy H. Crawford. "Human monoclonal antibodies—production and potential applications." Serodiagnosis and Immunotherapy in Infectious Disease 1, no. 2 (April 1987): 83–86. http://dx.doi.org/10.1016/0888-0786(87)90011-4.

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39

Haniu, Hisao, Naoto Saito, Yoshikazu Matsuda, Tamotsu Tsukahara, Yuki Usui, Nobuyo Narita, Kazuo Hara, et al. "Basic Potential of Carbon Nanotubes in Tissue Engineering Applications." Journal of Nanomaterials 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/343747.

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Carbon nanotubes (CNTs) are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs)in vivoandin vitrofor the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTsin vivoandin vitroobserved by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups.

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40

Javaid, Mohd, Abid Haleem, Ravi Pratap Singh, Mir Irfan Ul Haq, Ankush Raina, and Rajiv Suman. "Industry 5.0: Potential Applications in COVID-19." Journal of Industrial Integration and Management 05, no. 04 (November 19, 2020): 507–30. http://dx.doi.org/10.1142/s2424862220500220.

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Industry 5.0, the fifth industrial revolution, consists of smart digital information and manufacturing technologies. This industrial revolution generates effective processes and makes rapid improvement in industries and healthcare. Solutions to challenges posed by COVID-19 pandemic can be identified with the deployment of Industry 5.0-based technologies. It helps to provide personalized therapy and treatment processes to the COVID-19 patients if a detailed patient’s information is available. The aim of Industry 5.0 technologies is to create a smart healthcare environment with real-time capabilities. During the COVID-19 pandemic, these technologies can provide a remote monitoring system in healthcare. This paper identifies and studies major technologies of Industry 5.0 helpful for the COVID-19 pandemic. The supportive features of Industry 5.0 for the COVID-19 pandemic are discussed diagrammatically. Finally, we identified and studied significant challenges faced in the context of Industry 5.0 technologies for the COVID-19 pandemic. The literature revealed that this technological innovation allows a high personalization level to fulfill personal specific demands of the patient and doctors. These technologies play a significant role in making the life of doctors better. Further, doctors can use this technology to focus on critically infected patients and provide proper appropriate information regarding their better treatment. Moreover, Industry 5.0 technologies can help doctors and medical students for required medical training during this COVID-19 outbreak.

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41

Friesel, D. L., and T. A. Antaya. "Medical Cyclotrons." Reviews of Accelerator Science and Technology 02, no. 01 (January 2009): 133–56. http://dx.doi.org/10.1142/s1793626809000272.

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Particle accelerators were initially developed to address specific scientific research goals, yet they were used for practical applications, particularly medical applications, within a few years of their invention. The cyclotron's potential for producing beams for cancer therapy and medical radioisotope production was realized with the early Lawrence cyclotrons and has continued with their more technically advanced successors — synchrocyclotrons, sector-focused cyclotrons and superconducting cyclotrons. While a variety of other accelerator technologies were developed to achieve today's high energy particles, this article will chronicle the development of one type of accelerator — the cyclotron, and its medical applications. These medical and industrial applications eventually led to the commercial manufacture of both small and large cyclotrons and facilities specifically designed for applications other than scientific research.

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42

Peng, Xiao Yu. "Potential Biomedical Applications of Terahertz Technologies." American Journal of Biomedical Science & Research 10, no. 2 (September 3, 2020): 149–51. http://dx.doi.org/10.34297/ajbsr.2020.08.001490.

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43

Yuen, Jonathan D., Lisa C. Shriver-Lake, Scott A. Walper, Daniel Zabetakis, Joyce C. Breger, and David A. Stenger. "Microbial Nanocellulose Printed Circuit Boards for Medical Sensing." Sensors 20, no. 7 (April 6, 2020): 2047. http://dx.doi.org/10.3390/s20072047.

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We demonstrate the viability of using ultra-thin sheets of microbially grown nanocellulose to build functional medical sensors. Microbially grown nanocellulose is an interesting alternative to plastics, as it is hydrophilic, biocompatible, porous, and hydrogen bonding, thereby allowing the potential development of new application routes. Exploiting the distinguishing properties of this material enables us to develop solution-based processes to create nanocellulose printed circuit boards, allowing a variety of electronics to be mounted onto our nanocellulose. As proofs of concept, we have demonstrated applications in medical sensing such as heart rate monitoring and temperature sensing—potential applications fitting the wide-ranging paradigm of a future where the Internet of Things is dominant.

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44

Ali, Fayaz, Narayan S Hosmane, and Yinghuai Zhu. "Boron Chemistry for Medical Applications." Molecules 25, no. 4 (February 13, 2020): 828. http://dx.doi.org/10.3390/molecules25040828.

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Boron compounds now have many applications in a number of fields, including Medicinal Chemistry. Although the uses of boron compounds in pharmacological science have been recognized several decades ago, surprisingly few are found in pharmaceutical drugs. The boron-containing compounds epitomize a new class for medicinal chemists to use in their drug designs. Carboranes are a class of organometallic compounds containing carbon (C), boron (B), and hydrogen (H) and are the most widely studied boron compounds in medicinal chemistry. Additionally, other boron-based compounds are of great interest, such as dodecaborate anions, metallacarboranes and metallaboranes. The boron neutron capture therapy (BNCT) has been utilized for cancer treatment from last decade, where chemotherapy and radiation have their own shortcomings. However, the improvement in the already existing (BPA and/or BSH) localized delivery agents or new tumor-targeted compounds are required before realizing the full clinical potential of BNCT. The work outlined in this short review addresses the advancements in boron containing compounds. Here, we have focused on the possible clinical implications of the new and improved boron-based biologically active compounds for BNCT that are reported to have in vivo and/or in vitro efficacy.

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Hou, Wanting, Ruiqi Liu, Siwei Bi, Qian He, Haibo Wang, and Jun Gu. "Photo-Responsive Polymersomes as Drug Delivery System for Potential Medical Applications." Molecules 25, no. 21 (November 5, 2020): 5147. http://dx.doi.org/10.3390/molecules25215147.

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Due to a strong retardation effect of o-nitrobenzyl ester on polymerization, it is still a great challenge to prepare amphiphilic block copolymers for polymersomes with a o-nitrobenzyl ester-based hydrophobic block. Herein, we present one such solution to prepare amphiphilic block copolymers with pure poly (o-nitrobenzyl acrylate) (PNBA) as the hydrophobic block and poly (N,N’-dimethylacrylamide) (PDMA) as the hydrophilic block using bulk reversible addition-fragmentation chain transfer (RAFT) polymerization of o-nitrobenzyl acrylate using a PDMA macro-RAFT agent. The developed amphiphilic block copolymers have a suitable hydrophobic/hydrophilic ratio and can self-assemble into photoresponsive polymersomes for co-loading hydrophobic and hydrophilic cargos into hydrophobic membranes and aqueous compartments of the polymersomes. The polymersomes demonstrate a clear photo-responsive characteristic. Exposure to light irradiation at 365 nm can trigger a photocleavage reaction of o-nitrobenzyl groups, which results in dissociation of the polymersomes with simultaneous co-release of hydrophilic and hydrophobic cargoes on demand. Therefore, these polymersomes have great potential as a smart drug delivery nanocarrier for controllable loading and releasing of hydrophilic and hydrophobic drug molecules. Moreover, taking advantage of the conditional releasing of hydrophilic and hydrophobic drugs, the drug delivery system has potential use in medical applications such as cancer therapy.

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Zhao, Jing, Zhuwen Chen, Mengying Yu, Qian Wu, Chao Yang, Mei Hong, Yiyong Yan, Jian Zhang, and Ling Zhang. "The small molecule optical probes for gases with potential medical applications." SCIENTIA SINICA Chimica 45, no. 11 (November 1, 2015): 1145–58. http://dx.doi.org/10.1360/n032015-00112.

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Li, Yupeng, Xiaoyun Lu, Xiaomei Ren, and Ke Ding. "Small Molecule Discoidin Domain Receptor Kinase Inhibitors and Potential Medical Applications." Journal of Medicinal Chemistry 58, no. 8 (January 21, 2015): 3287–301. http://dx.doi.org/10.1021/jm5012319.

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HAZER, Baki. "Amphiphilic Poly (3-Hydroxy Alkanoate)s: Potential Candidates for Medical Applications." Energy and Power Engineering 02, no. 01 (2010): 31–38. http://dx.doi.org/10.4236/epe.2010.21006.

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Ge, Chenjiao, Mingli Li, Mingxuan Li, and Ali Ahmadi Peyghan. "Au-decorated BN nanotube as a breathalyzer for potential medical applications." Journal of Molecular Liquids 312 (August 2020): 113454. http://dx.doi.org/10.1016/j.molliq.2020.113454.

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Alves, Eliana, Maria A. F. Faustino, Maria G. P. M. S. Neves, Ângela Cunha, Helena Nadais, and Adelaide Almeida. "Potential applications of porphyrins in photodynamic inactivation beyond the medical scope." Journal of Photochemistry and Photobiology C: Photochemistry Reviews 22 (March 2015): 34–57. http://dx.doi.org/10.1016/j.jphotochemrev.2014.09.003.

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