Academic literature on the topic 'Mechanotransduction'
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Journal articles on the topic "Mechanotransduction"
French, A. S. "Mechanotransduction." Annual Review of Physiology 54, no. 1 (October 1992): 135–52. http://dx.doi.org/10.1146/annurev.ph.54.030192.001031.
Full textQin, Yi-Xian, and Minyi Hu. "Mechanotransduction in Musculoskeletal Tissue Regeneration: Effects of Fluid Flow, Loading, and Cellular-Molecular Pathways." BioMed Research International 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/863421.
Full textLuis Alonso, José, and Wolfgang H. Goldmann. "Cellular mechanotransduction." AIMS Biophysics 3, no. 1 (2016): 50–62. http://dx.doi.org/10.3934/biophy.2016.1.50.
Full textChalfie, Martin. "Neurosensory mechanotransduction." Nature Reviews Molecular Cell Biology 10, no. 1 (January 2009): 44–52. http://dx.doi.org/10.1038/nrm2595.
Full textHansen, Caroline E., Yongzhi Qiu, Owen J. T. McCarty, and Wilbur A. Lam. "Platelet Mechanotransduction." Annual Review of Biomedical Engineering 20, no. 1 (June 4, 2018): 253–75. http://dx.doi.org/10.1146/annurev-bioeng-062117-121215.
Full textPersat, Alexandre. "Bacterial mechanotransduction." Current Opinion in Microbiology 36 (April 2017): 1–6. http://dx.doi.org/10.1016/j.mib.2016.12.002.
Full textLeckband, Deborah. "Intercellular Mechanotransduction." Biophysical Journal 114, no. 3 (February 2018): 555a. http://dx.doi.org/10.1016/j.bpj.2017.11.3033.
Full textStewart, Sarah, Alastair Darwood, Spyros Masouros, Claire Higgins, and Arul Ramasamy. "Mechanotransduction in osteogenesis." Bone & Joint Research 9, no. 1 (January 2020): 1–14. http://dx.doi.org/10.1302/2046-3758.91.bjr-2019-0043.r2.
Full textUray, Iván P., and Karen Uray. "Mechanotransduction at the Plasma Membrane-Cytoskeleton Interface." International Journal of Molecular Sciences 22, no. 21 (October 26, 2021): 11566. http://dx.doi.org/10.3390/ijms222111566.
Full textSun, Zhiqi, Shengzhen S. Guo, and Reinhard Fässler. "Integrin-mediated mechanotransduction." Journal of Cell Biology 215, no. 4 (November 8, 2016): 445–56. http://dx.doi.org/10.1083/jcb.201609037.
Full textDissertations / Theses on the topic "Mechanotransduction"
Huang, Wei. "Polycystin-1 and Bone Mechanotransduction." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10279.
Full textChronopoulos, Antonios. "Mechanotransduction in health and disease." Thesis, Imperial College London, 2017. http://hdl.handle.net/10044/1/56622.
Full textPucker, Andrew David. "Mechanotransduction in the Ciliary Muscle." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1460647729.
Full textMalone, Amanda Michelle Dolphin. "Mechanotransduction mechanisms in bone cells /." May be available electronically:, 2007. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.
Full textKuck, Jan L. "Mechanotransduction in red blood cells." Thesis, Griffith University, 2023. http://hdl.handle.net/10072/421118.
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Doctor of Philosophy (PhD)
School of Health Sci & Soc Wrk
Griffith Health
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Bays, Jennifer McQuown. "Mechanisms of E-cadherin mechanotransduction." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5711.
Full textBouclet, Adrien. "Evolutionary implication of mechanotransduction in development." Phd thesis, Université René Descartes - Paris V, 2014. http://tel.archives-ouvertes.fr/tel-01071238.
Full textAragona, Mariaceleste. "Role of YAP/TAZ in Mechanotransduction." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422159.
Full textLe cellule percepiscono il loro microambiente non solo attraverso molecole segnale e fattori solubili ma anche attraverso stimoli fisici e meccanici. Le cellule traducono questi stimoli in segnali biochimici attraverso un processo definito meccanotrasduzione, in grado di regolare numerosi aspetti del comportamento cellulare, tra cui crescita, differenziamento e progressione tumorale. Tuttavia, non è ancora noto come la percezione dei segnali meccanici si traduca nell’attivazione di specifici fattori di trascrizione a livello nucleare. Questo lavoro individua YAP (Yes-associated protein), e TAZ (transcriptional coactivator with PDZ-binding motif, anche noto come WWTR1), omologhi di Yorkie in Drosophila, quali fattori di trascrizione in grado di rispondere ai segnali meccanici generati dalla rigidità della matrice extracellulare e dalla forma propria di ogni singola cellula. Questa regolazione richiede l’attivazione della GTPase Rho e la presenza di un citoscheletro di actina contrattile, ma è indipendente dall’attività della via di segnale delle chinasi Hippo e LATS. Non solo YAP/TAZ vengono regolati da segnali meccanici, ma sono anche funzionalmente richiesti per il differenziamento delle cellule staminali mesenchimali indotto dalla stiffness (elasticità o rigidità) della matrice e per la sopravvivenza delle cellule endoteliali regolata dalla geometria cellulare. In maniera complementare, l’espressione di una forma attivata di YAP domina sull’azione degli stimoli fisici nel determinare il destino cellulare. Queste scoperte identificano YAP/TAZ come sensori e mediatori degli stimoli meccanici indotti dal microambinete cellulare.
Dutour, Provenzano Gaëlle. "Role of intermediate filaments in mechanotransduction." Electronic Thesis or Diss., Sorbonne université, 2021. http://www.theses.fr/2021SORUS364.
Full textCells continuously adapt to their microenvironment. In particular, they modulate their morphology, growth, division, and motility according to the biochemical and physical properties of the extracellular matrix (ECM). Cells are equipped with adhesive structures called FAs, allowing them to interact with ECM proteins through the core transmembrane proteins called integrins and to sense the nature and the rigidity of the ECM. This information are transduced by FA proteins and lead, for instance, to changes in acto-myosin-mediated mechanical tension. Downstream signalling pathways also reach the nucleus; gene expression is then modified and may, in return, affect the composition of FAs or of the ECM proteins for adaptative cell response. Here, we hypothesized that, in addition to signalling pathways, a direct mechanical coupling between the events occurring at the cell periphery and the nucleus may participate in the transmission of mechanical cues and the regulation of nuclear functions. Although intermediate filaments (IFs) have extremely interesting mechanical properties and resist high tension load, their involvement in mechanotransduction pathways remains elusive. Using astrocyte as a model, due to its specific combination of IFs: vimentin, GFAP, nestin, and synemin, we studied first the effect of substrate rigidity on the nucleus morphology and function, and on the organisation of IFs around the nucleus. Then, we investigated the role of IFs in rigidity-induced nuclear changes. Using a combination of microfabrication techniques, biochemical and microscopy methods, we showed that substrate rigidity affects the nucleus shape, volume, and structure of the chromatin and the recruitment of transcription factor (YAP) and IFs are mediating these changes. Our results suggest that IFs form a cage-like structure around the nucleus in a rigidity-dependent manner: stiffer substrates promote the formation of a cage of vimentin and nestin. In the absence of IFs, the nuclear changes induced by rigidity are different than with IF. The nucleus increases its size in soft substrate, together with an increase in tension measured by YAP localising in the nucleus. The structure of the chromatin is changed. Altogether, the results obtained during our investigation give a better understanding of the role of intermediate filaments in the mechanosensitive nuclear responses
Huesa, Carmen. "Mechanotransduction in cells of the osteoblast lineage." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25468.
Full textBooks on the topic "Mechanotransduction"
Mofrad, Mohammad R. K., and Roger D. Kamm, eds. Cellular Mechanotransduction. Cambridge: Cambridge University Press, 2009. http://dx.doi.org/10.1017/cbo9781139195874.
Full textMatti, Weckström, and Tavi Pasi, eds. Cardiac mechanotransduction. Austin, TX: Landes Bioscience/Eurekah.com, 2007.
Find full textKamkin, Andre, and Irina Kiseleva, eds. Mechanosensitivity and Mechanotransduction. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-90-481-9881-8.
Full textKamkin, Andre. Mechanosensitivity and Mechanotransduction. Dordrecht: Springer Science+Business Media B.V., 2011.
Find full textXiong, Wei, and Zhigang Xu. Mechanotransduction of the Hair Cell. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8557-4.
Full textD, Kamm Roger, ed. Cellular mechanotransduction: Diverse perspectives from molecules to tissues. Cambridge: Cambridge University Press, 2009.
Find full textChow, Michelle Sze-Weng. The role of focal adhesions in myometrial mechanotransduction. Ottawa: National Library of Canada, 2003.
Find full textYu-li, Wang, and Discher Dennis E, eds. Cell mechanics. Amsterdam: Elsevier Academic Press, 2007.
Find full textDionne, Gilman. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins. [New York, N.Y.?]: [publisher not identified], 2020.
Find full textLee, Kristen Lauren. A Mechanism of Mechanotransduction Mediated by the Primary Cilium. [New York, N.Y.?]: [publisher not identified], 2014.
Find full textBook chapters on the topic "Mechanotransduction"
Gooch, Keith J., and Christopher J. Tennant. "Mechanotransduction." In Mechanical Forces: Their Effects on Cells and Tissues, 123–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-662-03420-0_6.
Full textKim, Sung Soo. "Mechanotransduction, Models." In Encyclopedia of Computational Neuroscience, 1676–83. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-6675-8_380.
Full textWarnock, James N. "Endothelial Mechanotransduction." In Advances in Heart Valve Biomechanics, 37–58. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-01993-8_2.
Full textKim, Sung Soo. "Mechanotransduction, Models." In Encyclopedia of Computational Neuroscience, 1–9. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7320-6_380-2.
Full textLiang, Xin, Landi Sun, and Zhen Liu. "Drosophila Mechanotransduction Channels." In SpringerBriefs in Biochemistry and Molecular Biology, 63–79. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-6526-2_5.
Full textLeckband, D. E. "Cadherins in Mechanotransduction." In Molecular and Cellular Mechanobiology, 57–80. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-5617-3_3.
Full textYip, Kay-Pong, Lavanya Balasubramanian, and James S. K. Sham. "Integrin-Mediated Mechanotransduction in Vascular Smooth Muscle Cells." In Mechanosensitivity and Mechanotransduction, 3–24. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9881-8_1.
Full textParker, James C., and Mary I. Townsley. "Control of TRPV4 and Its Effect on the Lung." In Mechanosensitivity and Mechanotransduction, 239–54. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9881-8_10.
Full textRubacha, Matthew, and Mingyao Liu. "The Role of Protein-protein Interactions in Mechanotransduction: Implications in Ventilator Induced Lung Injury." In Mechanosensitivity and Mechanotransduction, 255–73. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9881-8_11.
Full textYoung, Suzanne R. L., and Fredrick M. Pavalko. "Cellular Mechanisms of Mechanotransduction in Bone." In Mechanosensitivity and Mechanotransduction, 277–96. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9881-8_12.
Full textConference papers on the topic "Mechanotransduction"
Kaazempur-Mofrad, Mohammad R., Peter J. Mack, Helene Karcher, Javad Golji, and Roger G. Kamm. "Stress-Induced Mechanotransduction: Some Preliminaries." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43215.
Full textWan, Qiaoqiao, Eunhye Cho, Seungman Park, Bumsoo Han, Hiroki Yokota, and Sungsoo Na. "Visualizing Chondrocyte Mechanotransduction in 3D." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14484.
Full textMilewski, Andrew, Dáibhid Ó. Maoiléidigh, and A. J. Hudspeth. "Homeostatic enhancement of active mechanotransduction." In TO THE EAR AND BACK AGAIN - ADVANCES IN AUDITORY BIOPHYSICS: Proceedings of the 13th Mechanics of Hearing Workshop. Author(s), 2018. http://dx.doi.org/10.1063/1.5038515.
Full textMolladavoodi, Sara, John B. Medley, Maud Gorbet, and H. J. Kwon. "Mechanotransduction in Corneal Epithelial Cells." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-65406.
Full textMofrad, Mohammad R. K. "Molecular Mechanosensors and Focal Adhesion Mechanotransduction." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19707.
Full textWarren, Ben. "Unravelling mechanotransduction in the locust ear." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.111920.
Full textTamaddoni, Nima, and Stephen A. Sarles. "Mechanotransduction of Multi-Hair Droplet Arrays." In ASME 2014 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/smasis2014-7551.
Full textPatel, Sagar S., Ramesh Natarajan, and Rebecca L. Heise. "Mechanotransduction of Primary Cilia in Lung Adenocarcinoma." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80435.
Full textHolle, Andrew W., Juan Carlos Del Alamo, and Adam J. Engler. "Focal Adhesion Mechanotransduction Regulates Stiffness-Directed Differentiation." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14676.
Full textNovak, Caymen, Eric Horst, Ciara Davis, and Geeta Mehta. "Abstract TMIM-080: MECHANOTRANSDUCTION IN OVARIAN CANCERS." In Abstracts: 12th Biennial Ovarian Cancer Research Symposium; September 13-15, 2018; Seattle, Washington. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1557-3265.ovcasymp18-tmim-080.
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