Relevant bibliographies by topics / ME/CFS

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'ME/CFS'

Author: Grafiati
Published: 4 June 2021
Last updated: 31 January 2023

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Journal articles on the topic "ME/CFS"

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Denman, AM. "AIDS and CFS/ME." Clinical Medicine 3, no. 2 (March 1, 2003): 188.2–188. http://dx.doi.org/10.7861/clinmedicine.3-2-188a.

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SHEPHERD, C. "Research Update Note on ME (ME/CFS)." British Journal of Social Work 27, no. 5 (October 1, 1997): 755–60. http://dx.doi.org/10.1093/oxfordjournals.bjsw.a011264.

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Taylor, Anna K., Maria Loades, Amberly LC Brigden, Simon M. Collin, and Esther Crawley. "‘It’s personal to me’: A qualitative study of depression in young people with CFS/ME." Clinical Child Psychology and Psychiatry 22, no. 2 (October 14, 2016): 326–40. http://dx.doi.org/10.1177/1359104516672507.

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Background: Paediatric chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) has a prevalence of 0.4–2.4% and is defined as ‘generalised disabling fatigue persisting after routine tests and investigations have failed to identify an obvious underlying cause’. One-third of young people with CFS/ME have probable depression. Little is known about why depression develops, the relationship between depression and CFS/ME, or what treatment might be helpful. Methods: We conducted nine semi-structured interviews with young people with CFS/ME (aged 13–17 years, 8/9 female) and probable depression, covering perceived causes of depression, the relationship between CFS/ME and depression, and treatment strategies. Results: Most thought CFS/ME caused depression. Many discussed a cyclical relationship: low mood made CFS/ME worse. A sense of loss was common. CFS/ME restricted activities participants valued and changed systemic structures, causing depression. There was no single helpful treatment approach. Individualised approaches using combinations of cognitive behavioural therapy (CBT), medication, activity management and other strategies were described. Conclusion: This study suggests that depression may be secondary to CFS/ME in young people because of the impact of CFS/ME on quality of life. Clinicians treating young people with CFS/ME need to consider strategies to prevent development of depression, and research is needed into approaches that are effective in treating CFS/ME with co-morbid depression.
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Josev, Elisha K., Rebecca C. Cole, Adam Scheinberg, Katherine Rowe, Lionel Lubitz, and Sarah J. Knight. "Health, Wellbeing, and Prognosis of Australian Adolescents with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Case-Controlled Follow-Up Study." Journal of Clinical Medicine 10, no. 16 (August 16, 2021): 3603. http://dx.doi.org/10.3390/jcm10163603.

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Background: The purpose of this study was to follow-up an Australian cohort of adolescents newly-diagnosed with ME/CFS at a tertiary paediatric ME/CFS clinic and healthy controls over a mean period of two years (range 1–5 years) from diagnosis. Objectives were to (a) examine changes over time in health and psychological wellbeing, (b) track ME/CFS symptomatology and fulfillment of paediatric ME/CFS diagnostic criteria over time, and (c) determine baseline predictors of ME/CFS criteria fulfilment at follow-up. Methods: 34 participants aged 13–18 years (25 ME/CFS, 23 controls) completed standardised questionnaires at diagnosis (baseline) and follow-up assessing fatigue, sleep quality and hygiene, pain, anxiety, depression, and health-related quality of life. ME/CFS symptomatology and diagnostic criteria fulfilment was also recorded. Results: ME/CFS patients showed significant improvement in most health and psychological wellbeing domains over time, compared with controls who remained relatively stable. However, fatigue, pain, and health-related quality of life remained significantly poorer amongst ME/CFS patients compared with controls at follow-up. Sixty-five percent of ME/CFS patients at baseline continued to fulfil ME/CFS diagnostic criteria at follow-up, with pain the most frequently experienced symptom. Eighty-two percent of patients at follow-up self-reported that they still had ME/CFS, with 79% of these patients fulfilling criteria. No significant baseline predictors of ME/CFS criteria fulfilment at follow-up were observed, although pain experienced at baseline was significantly associated with criteria fulfilment at follow-up (R = 0.6, p = 0.02). Conclusions: The majority of Australian adolescents with ME/CFS continue to fulfil diagnostic criteria at follow-up, with fatigue, pain, and health-related quality of life representing domains particularly relevant to perpetuation of ME/CFS symptoms in the early years following diagnosis. This has direct clinical impact for treating clinicians in providing a more realistic prognosis and highlighting the need for intervention with young people with ME/CFS at the initial diagnosis and start of treatment.
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Jason, Leonard A., Suzanna So, Meredyth Evans, Abigail Brown, Madison Sunnquist, Young Im, and Charles Schafer. "An Overview of Operationalizing Criteria for ME, ME/CFS, and CFS Case Definitions." Journal of Prevention & Intervention in the Community 43, no. 1 (January 2, 2015): 1–4. http://dx.doi.org/10.1080/10852352.2014.973237.

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Ryabkova, Varvara A., Natalia Y. Gavrilova, Tamara V. Fedotkina, Leonid P. Churilov, and Yehuda Shoenfeld. "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post-COVID Syndrome: A Common Neuroimmune Ground?" Diagnostics 13, no. 1 (December 26, 2022): 66. http://dx.doi.org/10.3390/diagnostics13010066.

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Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology, sharing a similar clinical presentation with the increasingly recognized post-COVID syndrome. We performed the first cross-sectional study of ME/CFS in a community population in Russia. Then we described and compared some clinical and pathophysiological characteristics of ME/CFS and post-COVID syndrome as neuroimmune disorders. Of the cohort of 76 individuals who suggested themselves as suffering from ME/CFS, 56 were diagnosed with ME/CFS by clinicians according to ≥1 of the four most commonly used case definitions. Of the cohort of 14 individuals with post-COVID-19 syndrome, 14 met the diagnostic criteria for ME/CFS. The severity of anxiety/depressive symptoms did not correlate with the severity of fatigue either in ME/CFS or in post-COVID ME/CFS. Still, a positive correlation was found between the severity of fatigue and 20 other symptoms of ME/CFS related to the domains of “post-exertional exhaustion”, “immune dysfunction”, “sleep disturbances”, “dysfunction of the autonomic nervous system”, “neurological sensory/motor disorders” and “pain syndromes”. Immunological abnormalities were identified in 12/12 patients with ME/CFS according to the results of laboratory testing. The prevalence of postural orthostatic tachycardia assessed in the active orthostatic test amounted to 37.5% in ME/CFS and 75.0% in post-COVID ME/CFS (the latter was higher than in healthy controls, p = 0.02). There was a more pronounced increase in heart rate starting from the 6th minute of the test in post-COVID ME/CFS compared with the control group. Assessment of the functional characteristics of microcirculation by laser doppler flowmetry revealed obvious and very similar changes in ME/CFS and post-COVID ME/CFS compared to the healthy controls. The identified laser doppler flowmetry pattern corresponded to the hyperemic form of microcirculation disorders usually observed in acute inflammatory response or in case of systemic vasoconstriction failure.
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Mandarano, Alexandra H., Ludovic Giloteaux, Betsy A. Keller, Susan M. Levine, and Maureen R. Hanson. "Eukaryotes in the gut microbiota in myalgic encephalomyelitis/chronic fatigue syndrome." PeerJ 6 (January 22, 2018): e4282. http://dx.doi.org/10.7717/peerj.4282.

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Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) often suffer from gastrointestinal symptoms and many are diagnosed with irritable bowel syndrome (IBS). Previous studies, including from our laboratory, have demonstrated that the ME/CFS gut bacterial composition is altered and less diverse when compared to healthy individuals. Patients have increased biomarkers of inflammation and leaky gut syndrome. To further investigate dysbiosis in the ME/CFS gut microbiome, we sought to characterize the eukaryotes present in the gut of 49 individuals with ME/CFS and 39 healthy controls. Using 18S rRNA sequencing, we have identified eukaryotes in stool samples of 17 healthy individuals and 17 ME/CFS patients. Our analysis demonstrates a small, nonsignificant decrease in eukaryotic diversity in ME/CFS patients compared to healthy individuals. In addition, ME/CFS patients show a nonsignificant increase in the ratio of fungal phyla Basidiomycota to Ascomycota, which is consistent with ongoing inflammation in ME/CFS. We did not identify specific eukaryotic taxa that are associated with ME/CFS disease status.
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Jahanbani, Fereshteh, Rajan D. Maynard, Justin Cyril Sing, Shaghayegh Jahanbani, John J. Perrino, Damek V. Spacek, Ronald W. Davis, and Michael P. Snyder. "Phenotypic characteristics of peripheral immune cells of Myalgic encephalomyelitis/chronic fatigue syndrome via transmission electron microscopy: A pilot study." PLOS ONE 17, no. 8 (August 9, 2022): e0272703. http://dx.doi.org/10.1371/journal.pone.0272703.

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Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex chronic multi-systemic disease characterized by extreme fatigue that is not improved by rest, and worsens after exertion, whether physical or mental. Previous studies have shown ME/CFS-associated alterations in the immune system and mitochondria. We used transmission electron microscopy (TEM) to investigate the morphology and ultrastructure of unstimulated and stimulated ME/CFS immune cells and their intracellular organelles, including mitochondria. PBMCs from four participants were studied: a pair of identical twins discordant for moderate ME/CFS, as well as two age- and gender- matched unrelated subjects—one with an extremely severe form of ME/CFS and the other healthy. TEM analysis of CD3/CD28-stimulated T cells suggested a significant increase in the levels of apoptotic and necrotic cell death in T cells from ME/CFS patients (over 2-fold). Stimulated Tcells of ME/CFS patients also had higher numbers of swollen mitochondria. We also found a large increase in intracellular giant lipid droplet-like organelles in the stimulated PBMCs from the extremely severe ME/CFS patient potentially indicative of a lipid storage disorder. Lastly, we observed a slight increase in platelet aggregation in stimulated cells, suggestive of a possible role of platelet activity in ME/CFS pathophysiology and disease severity. These results indicate extensive morphological alterations in the cellular and mitochondrial phenotypes of ME/CFS patients’ immune cells and suggest new insights into ME/CFS biology.
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Shimosako, Nana, and Jonathan R. Kerr. "Use of single-nucleotide polymorphisms (SNPs) to distinguish gene expression subtypes of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)." Journal of Clinical Pathology 67, no. 12 (September 19, 2014): 1078–83. http://dx.doi.org/10.1136/jclinpath-2014-202597.

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AimsWe have reported gene expression changes in patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and the fact that such gene expression data can be used to identify subtypes of CFS/ME with distinct clinical phenotypes. Due to the difficulties in using a comparative gene expression method as an aid to CFS/ME disease and subtype-specific diagnosis, we have attempted to develop such a method based on single-nucleotide polymorphism (SNP) analysis.MethodsTo identify SNP allele associations with CFS/ME and CFS/ME subtypes, we tested genomic DNA of patients with CFS/ME (n=108), patients with endogenous depression (n=17) and normal blood donors (n=68) for 504 human SNP alleles located within 88 CFS-associated human genes using the SNP Genotyping GoldenGate Assay (Illumina, San Diego, California, USA). 360 ancestry informative markers (AIM) were also examined.Results21 SNPs were significantly associated with CFS/ME compared with depression and normal groups. 148 SNP alleles had a significant association with one or more CFS/ME subtypes. For each subtype, associated SNPs tended to be grouped together within particular genes. AIM SNPs indicated that 4 subjects were of Asian origin while the remainder were Caucasian. Hierarchical clustering of AIM data revealed the relatedness between 2 couples of patients with CFS only and confirmed the overall heterogeneity of all subjects.ConclusionsThis study provides evidence that human SNPs located within CFS/ME associated genes are associated with particular genomic subtypes of CFS/ME. Further work is required to develop this into a clinically useful subtype-specific diagnostic test.
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Vyas, Jui, Nina Muirhead, Ravinder Singh, Rachel Ephgrave, and Andrew Y. Finlay. "Impact of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) on the quality of life of people with ME/CFS and their partners and family members: an online cross-sectional survey." BMJ Open 12, no. 5 (May 2022): e058128. http://dx.doi.org/10.1136/bmjopen-2021-058128.

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ObjectivesThe aim of this study was to assess the impact of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) on the quality of life (QoL) of people with ME/CFS and their relative or partner (family member).DesignA patient-partner, multinational, subject-initiated, cross-sectional online survey.SettingInternational survey using ME/CFS charities, support groups and social media.ParticipantsParticipants were self-selected with recruitment via social media. Inclusion criteria were aged 18 years or over and reported diagnosis of ME/CFS by health professional. 1418 people with ME/CFS and their 1418 family members from 30 countries participated in the survey. Participants with ME/CFS had a mean age of 45.8 years (range 18–81) and were predominantly women (1214 (85.6%) of 1418). Family members had a mean age of 51.9 years (range 18–87) and were predominantly men (women: 504 (35.5%) of 1418). 991 (70%) family members were partners of the people with ME/CFS.InterventionsEuroQoL-5 Dimension (EQ-5D-3L), completed by people with ME/CFS, and Family Reported Outcome Measure (FROM-16) questionnaire, completed by family members.ResultsThe mean overall health status on a Visual Analogue Scale for people with ME/CFS was 33.8 (0=worst, 100=best). People with ME/CFS were most affected by ability to perform usual activities, pain, mobility, self-care and least impacted by anxiety. For family members, the overall mean FROM-16 score was 17.9 (0=no impact, 32=worst impact), demonstrating a major impact on QoL. Impact on QoL was significantly correlated between the person with ME/CFS and their family member (p<0.0001). Family members were most impacted emotionally by worry, frustration and sadness and personally by family activities, holidays, sex life and finances.ConclusionsTo the best of our knowledge, this is the largest study on the impact of the QoL of persons with ME/CFS and their family members. While open participation surveys are limited by selection bias, this research has revealed a significant worldwide burden of ME/CFS on the QoL of people with ME/CFS and their family members.
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Dissertations / Theses on the topic "ME/CFS"

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Carlsson, Sascha, and Charlotte Bernung. "ME/CFS - livskvalitet, aktivitetskompetens och värdering av aktivitet : En enkätstudie om myalgisk encefalomyelit/kroniskt trötthetssyndrom (ME/CFS)." Thesis, Hälsohögskolan, Högskolan i Jönköping, HHJ, Avd. för rehabilitering, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-40376.

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Bakgrund och syfte: ME/CFS påverkar i hög grad aktivitetsförmågan, med många olika kroppsliga symptom. Även små ansträngningar kan ge kraftig försämring. För fungerande vardag krävs planering och prioritering av aktiviteter, vilket förutsätter att den drabbade vet vilken ansträngning som åtgår och vad som är viktigast. I detta arbete undersöks hur ME/CFS-drabbade upplever förmågan att utföra vardagsaktiviteter, hur viktiga aktiviteterna är, i vilken grad uppgifter bortprioriteras av hälsoskäl samt hur hälsorelaterad livskvalitet skattas. Metod: Enkätundersökningen besvarades av 32 respondenter (16-76 år) med diagnostiserad ME/CFS. Aktivitetskompetens och värdering skattades med Min Mening och hälsorelaterad livskvalitet med SF-36. Det frågades också om aktiviteten bortprioriteras av hälsoskäl. Sämsta och bästa läge kunde anges för att återge eventuell variation i förmåga. Resultat: Aktivitetskompetensen skattas lågt (28 - 35 av 100) och värdering av aktiviteter ligger betydligt högre (61). Hälsorelaterad livskvalitet redovisas för åtta områden, där fysisk rollförmåga är särskilt låg (2 av 100). Vitalitet (10), fysisk funktion (24) och allmän hälsa (25) skattas också lågt. Slutsats: Personer med ME/CFS kan uppleva mycket stora begränsningar i vardagliga aktiviteter vilket kan leda till låg aktivitet och delaktighet. De värderar aktivitet högt och sjukdomen leder därför till ofrivillig isolering som måste motverkas av kunnig sjukvårdspersonal med kompetens inom energibesparande tekniker.
Background and purpose: ME/CFS widely affects occupational competence, with many various physical symptoms. Even small efforts can cause severe deterioration. To achieve a functioning everyday life, planning and prioritization is crucial, and the individual must know what effort is needed for each activity and what matters most. This thesis examines how people with ME/CFS experience their ability to perform everyday activities, the value of activities, if activities are avoided for health reasons, and how health-related quality of life is assessed. Method: The survey was answered by 32 ME/CFS-diagnosed respondents (16-76 years). Occupational competence and the value of occupations were assessed by Occupational Self Assessment (OSA), and health-related quality of life by SF-36. It was also asked if respondents refrained from activity for health reasons. The respondents were able to specify worst and best case to reflect fluctuations. Results: Occupational competence is assessed low (28-35 out of 100) and the value of activities is assessed considerably higher (61). Health-related quality of life is reported for eight subscales, where physical ability to exercise roles is particularly low (2 out of 100). Vitality (10), Physical Functioning (24) and General Health (25) are also scored low. Conclusion: People with ME / CFS can experience very high limitations in everyday activities, which can lead to low degree of activity and participation. They value activity high and the disease therefore leads to involuntary isolation that must be counteracted by proficient healthcare professionals with expertise in energy-saving technologies.
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Oliver, Nicholas. "ME/CFS, medicine and self help groups : a qualitative exploration." Thesis, University of East London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.532426.

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Morris, Dorothy, and mikewood@deakin edu au. "Double disability: Lived experience of Australian Tertiary Students with ME/CFS." Deakin University, 2003. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20051110.110308.

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This research is the exploration of the lived experience of tertiary students in Australia with the medical condition usually known as ME/CFS (Myalgic Encephalomyelitis /Chronic Fatigue Syndrome) seeking to explore issues of equity and human rights from the perspective of the Disability Discrimination Act 1992. Students feel that their difficulties are not caused just by the illness itself but by the failure of the tertiary institutions to understand the effects of this illness on them, the student, especially within the areas of accommodations and assessments. Their lived experiences are studied to ascertain if their experiences differ from those of other tertiary students. Forty participants came from every state and territory of Australia and twenty -four of Australia's universities as well as eight Technical and Further Education/Open Training Education Network (TAFE/OTEN) colleges are represented. The selection of the chosen methodology, Critical Ethnography from a Habermasian perspective, has been circumscribed by the medical condition which placed limitations on methodology and also data gathering methods. Non-structured stories, in which the participants wrote of their lived experience as students, were considered the most appropriate source of data. These were transmitted by electronic mail (with some by postal mail) to the researcher. A short questionnaire provided a participant background to the stories and was also collated for a composite overview of the participants. The stories are analysed in a number of ways: six selected stories are retold and the issues arising from these stories have been weighed against the remainder of the stories. Four intertwined themes were constructed from the issues raised in each story. Apparent infringements of the Disability Discrimination Act (1992) which impact on quality of life, human rights and equity are found. No accommodations are being made by the academic institutions for the cognitive dysfunctions and learning difficulties. Students are stigmatised and lack credibility to negotiate appropriate academic accommodations. A possible means of improving the ability of students to negotiate appropriate accommodations is explored. Finally the researcher reflects on her own involvement in the research as an 'insider' researcher.
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Stevenson, Clare. "Patient experience of cognitive behaviour therapy for chronic fatigue syndrome (CFS/ME)." Thesis, University of East London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.532532.

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Hemming, Claire. "Exploring the relationship between service-users' with CFS/ME and NHS professionals." Thesis, University of Leicester, 2005. http://hdl.handle.net/2381/31213.

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Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (hereafter referred to as CFS/ME) is a multi-system chronic illness, sufferers of which experience a range of symptoms that are often different in each individual case. The sole commonality amongst all sufferers appears to be severe and disabling fatigue (Sharpe et al. 1991). Despite the body of literature that has investigated the possible aetiology of CFS/ME, to date there is no known cause of the long-term condition (Erdman, 2003). Current systematic reviews of randomized control trials (RCTs) investigating the efficacy of treatment of CFS/ME identify cognitive-behavioural therapy (CBT) and graded exercise therapy (GET) as the most effective evidence-based interventions (Erdman, 2003; Bagnall et al. 2002). There are, however, inconsistencies and disagreement in the evidence-base, adding a further layer of uncertainty to an already uncertain long-term condition. A service-user dissatisfaction with NHS services and professionals are frequently reported in the CFS/ME literature, the current literature review explores whether attachment theory could offer a different and useful perspective regarding the treatment of people with CFS/ME. An attachment relationship can be defined as any relationship where proximity to the other affects perceived security (West & Sheldon-Kellor, 1994). Proximity seeking is most apparent when a person is frightened, fatigued or sick, and gains some relief by receiving comfort and care-giving (Bowlby, 1979). In view of reconsidering CFS/ME from an attachment theory perspective the latter of the literature review explores the current research regarding attachment theory and illness, and the available research linking adult attachment needs and engagement with Health Services. The relevance of using attachment theory to inform the treatment of people with CFS/ME is then discussed.
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Lynch, Sean Patrick Jeremy. "The nature of fatigue in the chronic fatigue syndrome : a longitudinal study." Thesis, Imperial College London, 1996. http://hdl.handle.net/10044/1/7496.

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Velleman, Sophie. "The psychological wellbeing of siblings of children with CFS/ME : a qualitative study." Thesis, University of Exeter, 2012. http://hdl.handle.net/10036/3716.

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Chronic Fatigue Syndrome or myalgic encephalopathy (CFS/ME) has a negative impact on a child and their parents. It is not known what the impact is for the siblings of children with CFS/ME. Nine siblings participated in semi-structured interviews. Siblings identified a number of negative impacts to their family and to themselves, as well as describing some protective family factors. These findings have implications for current practice in CFS/ME paediatric services.
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Berg, Ingrid Helene. "The Relationship Between Insomnia and CFS/ME : The HPA Axis as a Mediator." Thesis, Norges teknisk-naturvitenskapelige universitet, Psykologisk institutt, 2013. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-25191.

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Fatigue is common in the general population, and is the hallmark of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). Although the occurrence of sleep difficulties is known to be common in subjects with fatigue, research on insomnia in such subjects is absent. The current study sought to examine the impact comorbid insomnia has on level of fatigue in subjects with chronic fatigue. The aim of this study is to assess the relationship between insomnia and chronic fatigue, and examine if the relationship is affected by the endocrine activity in the HPA axis. The following hypotheses were tested: 1) Do patients with chronic fatigue and comorbid insomnia experience more fatigue than patients with chronic fatigue without comorbid insomnia? 2) Do patients with chronic fatigue and with initially comorbid insomnia experience more fatigue after treatment than chronic fatigue patients without comorbid insomnia? 3) Do patients with chronic fatigue who experience improvement in insomnia after treatment also experience less fatigue by the end of treatment compared with patients who do not experience improvement in insomnia? 4) Is the potential relationship between insomnia and chronic fatigue influenced by the activity of the HPA axis as expressed by variation in cortisol output measured by Trier Social Stress Test for Groups (TSST-G)? The study sample consisted of 75 patients with chronic fatigue. Thirty-three met criteria for insomnia, while 42 did not. While staying at Hysnes Rehabilitation Center in Trondheim, Norway, they received a work-related Acceptance and Commitment Therapy (ACT) treatment intervention lasting 3.5 weeks. In addition, they participated in a standardized stress test (Trier Social Stress Test) pre- and post-treatment. Saliva cortisol samples were collected during the test in order to measure variation in cortisol output. The current finding is the first description of how insomnia in patients with chronic fatigue is associated with higher levels of fatigue (p < .05). Further, this study gives preliminary support indicating that remission of insomnia in patients with chronic fatigue can significantly reduce levels of fatigue (p < .05), and furthermore improve the physiological stress-response (p < .05). These results might encourage clinicians to assess and provide specific treatment for insomnia in patients with chronic fatigue as this might improve their treatment results. An aim for further research should be to investigate the effect of specified treatment for insomnia in patients with chronic fatigue.
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Lundblad, Anette, and Minna Kantola. "Arbetsterapeutiska interventioner för vuxna med ME/CFS och betydelsen för aktivitetsbalans : En litteraturöversikt." Thesis, Luleå tekniska universitet, Hälsa och rehabilitering, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-79451.

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Syfte: Att beskriva och kartlägga arbetsterapeutiska interventioner för vuxna med ME/CFS och betydelsen för aktivitetsbalans. Metod: För att besvara syftet så utfördes en litteraturöversikt som inkluderar kvalitativa studier, kvantitativa studier och litteraturstudier, totalt åtta studier. Resultat: Arbetsterapeutiska interventioner har många fördelar som visar att arbetsterapi som används i rehabilitering har betydelse för vuxna med ME/CFS i det dagliga livet på olika sätt. Att aktiviteter skulle delas upp i relation till klientens aktivitetsnivåer och energinivåer synliggjordes. Individuell intervention som Pacing strategier och Gruppintervention som Gruppbaserad self-managementprogram kan användas som arbetsterapeutiska verktyg för diagnosgruppen ME/CFS och har betydelse för aktivitetsbalans. Det framkommer att kortsiktiga individuella interventioner kan vara kan vara effektiva och att Gruppbaserad self-managementprogram visar inga långvariga effekter. Slutsats: Uppsatsen visar fördelar att tillämpa Pacing som copingstrategi inom arbetsterapi för klienter med ME/CFS. Pacing strategier kan vara ett betydelsefullt arbetsterapeutiskt verktyg eftersom klienterna behöver strategier till att bespara sina energinivåer för meningsfulla aktiviteter. Pacing strategier visar ge goda effekter och beskrivs vara den säkraste intervention för klienter med ME/CFS. Pacing möjliggör för klienterna att uppnå aktivitetsbalans i vardagen. Arbetsterapeutisk gruppintervention som Gruppbaserad self-managementprogram kan vara en del av den arbetsterapeutiska rehabiliteringen av klienter med ME/CFS. Gruppbaserade self-managementprogram är funktionellt inom primärvården, vilket uppskattades av klienterna eftersom det möjliggör klientträffar med andra med samma diagnos. Genom gruppinterventionen har klienterna lärt sig att använda Copingstrategier och arbeta med sin acceptans. Gruppinterventionen resulterade att klienter lärde sig att undvika överansträngning, lärde sig att förändra levnadsvanor, energibesparing vilket kan stödja klienterna. Resultatet visar att efter genomförd gruppintervention är det betydelsefullt för klienter att hålla kontakten och skapa nätverk mellan klienterna. Arbetsterapi och arbetsterapeuten har betydelse för rehabiliteringen av klienter med ME/CFS och för deras aktivitetsbalans i dagliga livet. Det är viktigt att ta hänsyn till klientens uppfattningar, värderingar och synpunkter i relation till klientens diagnos. Ett dåligt bemötande och omhändertagande i hälso-och sjukvården kan påverka rehabiliteringen negativt. Det är betydelsefullt att arbetsterapeuten respekterar och har kunskapen om diagnosens pendlande symtom i samband med rehabiliteringsinsatser och interventioner. Det finns ett behov och efterfrågan om vidare forskning inom området, eftersom det är ett begränsat område gällande arbetsterapi och arbetsterapeutens betydelse i rehabilitering för klienter med ME/CFS som kan främja aktivitetsbalans.
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LUPO, GIUSEPPE FRANCESCO DAMIANO. "RUOLO POTENZIALE DEL MICROBIOMA NELLA SINDROME DA AFFATICAMENTO CRONICO/ ENCEFALOMIELITE MIALGICA (CFS/ME)." Doctoral thesis, Università Cattolica del Sacro Cuore, 2020. http://hdl.handle.net/10280/72840.

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La Sindrome da Affaticamento Cronico/Encefalomielite Mialgica (CFS/ME), è una grave malattia multisistemica caratterizzata da anomalie immunologiche e disfunzioni del metabolismo energetico. Recenti evidenze suggeriscono l’esistenza di una forte correlazione tra disbiosi e condizione patologica. La presente ricerca ha analizzato la composizione del microbiota intestinale ed orale in pazienti con CFS/ME rispetto a controlli sani e ha determinato se eventuali differenze osservate potrebbero essere utili in futuro per l'identificazione di biomarcatori diagnostici. La composizione batterica fecale e salivare dei pazienti con CFS/ME è stata studiata mediante sequenziamento Illumina degli ampliconi del gene 16S rRNA. Il microbiota fecale dei pazienti con CFS/ME ha mostrato una significativa riduzione di Lachnospiraceae, in particolare di Anaerostipes, rispetto ai gruppi di soggetti senza CFS/ME e un incremento di Phascolarctobacterium faecium e unclassified Ruminococcus. Bacteroides vulgatus, unclassified Bacteroides, Bacteroides uniformis e unclassified Barnesiella sono risultati significativamente più abbondanti nei pazienti con CFS/ME. Il microbiota orale dei pazienti con CFS/ME ha mostrato un aumento significativo di Rothia dentocariosa. Il profilo metabolico fecale di un sottogruppo di pazienti con CFS/ME ha mostrato un aumento complessivo di SCFA e di derivati dell'indolo rispetto ai gruppi non CFS/ME, suggerendo un aumento dei processi di fermentazione. I nostri risultati supportano l'ipotesi autoimmune per la CFS/ME e se saranno confermati da studi più ampi, le differenze rilevate nei profili microbici dei pazienti CFS/ME potrebbero essere utilizzate come markers per una diagnosi più accurata e per lo sviluppo di strategie terapeutiche specifiche.
The Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME), is a severe multisystemic disease characterized by immunological abnormalities and dysfunction of energy metabolism. Recent evidence suggest that there is a strong correlation between dysbiosis and pathological condition. The present research investigated the composition of the intestinal and oral microbiota in CFS/ME patients in comparison to healthy controls and determined whether any observed differences could be useful for the identification of diagnostic biomarkers. The fecal and salivary bacterial composition in CFS/ME patients was investigated by Illumina sequencing of 16S rRNA gene amplicons. The fecal microbiota of CFS/ME patients showed a significant reduction of Lachnospiraceae, particularly Anaerostipes, compared to the non-CFS/ME groups, and an increase of Phascolarctobacterium faecium and unclassified Ruminococcus. Bacteroides vulgatus, unclassified Bacteroides, Bacteroides uniformis and unclassified Barnesiella resulted significantly more abundant in CFS/ME patients. The oral microbiota of CFS/ME patients showed a significant increase of Rothia dentocariosa. The fecal metabolic profile of a subgroup of CFS/ME patients revealed an overall increase of SCFAs and indole derivatives compared to the non-CFS/ME groups, suggesting an increase in the fermentation processes. Our results support the autoimmune hypothesis for CFS/ME condition and if confirmed by larger studies, the differences detected in the microbial profiles of CFS/ME patients may be used as markers for a more accurate diagnosis and for the development of specific therapeutic strategies.
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Books on the topic "ME/CFS"

1

Michael, Sharpe, ed. Chronic fatigue syndrome (CFS/ME). 2nd ed. New York: Oxford University Press, 2008.

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Campling, Frankie. Chronic fatigue syndrome (CFS/ME). Oxford: Oxford University Press, 2000.

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Great Britain. Department of Health. Chronic fatigue syndrome/myalgic encephalopathy (CFS/ME). London: Department of Health, 2004.

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150 tips for everyday living with ME/CFS. UK: Anna Cayder, 2013.

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Whitmore, Trixie. Toxic chemical-free living and recovering from ME/CFS. Birchgrove, NSW, Australia: S. Milner Pub., 1990.

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Bell, David S. Neuro-immune fatigue ME/CFS/FM and cellular hypoxia. Livermore, CA: WingSpan Press, 2007.

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My teenage son had chronic fatigue: A mother's tale of ME/CFS. [Rouse Hill, N.S.W.]: Darien Estates, 2013.

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National Task Force on Chronic Fatigue Syndrome (CFS)/Post Viral Fatigue Syndrome (PVFS)/Myalgic Encephalomyelitis (ME). Report from the National Task Force on Chronic Fatigue Syndrome (CFS), Post Viral Fatigue Syndrome (PVFS), Myalgic Encephalomyelitis (ME). Bristol: Westcare, 1994.

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Dr, Murphy Gabrielle, ed. Coping better with chronic fatigue syndrome/myalgic encephalomyelitis: Cognitive behaviour therapy for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ ME). London: Karnac Books, 2009.

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Group, CFS/ME Working. A report of the CFS/ME Working Group: Report to the Chief Medical Officer of an independent Working Group. [U.K: the Group?], 2002.

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Book chapters on the topic "ME/CFS"

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Oette, Mark, Marvin J. Stone, Hendrik P. N. Scholl, Peter Charbel Issa, Monika Fleckenstein, Steffen Schmitz-Valckenberg, Frank G. Holz, et al. "ME/CFS." In Encyclopedia of Molecular Mechanisms of Disease, 1270–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_8012.

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Ward, Christopher D. "Neurologisation of CFS/ME: An Exchange." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 61–63. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_6.

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Saunders, Laura. "The Challenge of CFS/ME in Primary Care." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 153–64. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_11.

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Ward, Christopher D. "Scientifically Speaking: CFS/ME in the Medical Literature." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 26–33. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_3.

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Cromby, John. "The Public Meanings of CFS/ME: Making Up People." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 129–49. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_10.

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Ward, Christopher D. "The Said and the Unsaid: Ambivalence in CFS/ME." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 165–76. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_12.

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Horrocks, Matthew, and Christopher D. Ward. "Meanings of CFS/ME in the Lives of Couples." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 86–105. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_8.

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Ward, Christopher D., and Matthew Horrocks. "The Self and Others in CFS/ME: Reinterpreting Research Evidence." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 106–28. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_9.

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Rickards, Hugh. "Diagnostically Speaking: How should CFS/ME Be Classified — and Does it Matter?" In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 34–44. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_4.

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Ward, Christopher D. "Historically Speaking: Three Influences on the Way we Think about CFS/ME." In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue, 45–60. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137467324_5.

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Conference papers on the topic "ME/CFS"

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"ASARM - A System for CFS/ME Monitoring and Treatment." In International Conference on Biomedical Electronics and Devices. SciTePress - Science and and Technology Publications, 2012. http://dx.doi.org/10.5220/0003765701600166.

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Redfield, Signe, Mae Seto, and Nicholas D'Amore. "Assistive Robots for Long COVID and ME/CFS Support: Challenges and Opportunities." In 2022 IEEE Canadian Conference on Electrical and Computer Engineering (CCECE). IEEE, 2022. http://dx.doi.org/10.1109/ccece49351.2022.9918211.

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Themelis, Kristy, Robyn Stocks, Patrick Tano, Zdenka Cipinova, Lorraine Shah-Goodwin, Andrew Barritt, Hugo Critchley, Kevin Davies, and Jessica Eccles. "AB0907 AUTONOMIC AND INFLAMMATORY CHANGES IN FM AND ME/CFS AND THE CONTRIBUTION TO SIGNS AND SYMPTOMS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.1917.

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Stovall, M. C., P. Joseph, R. Pari, A. Warren, S. Miller, J. Squires, W. Xiao, A. B. Waxman, and D. M. Systrom. "Acute Effect of Pyridostigmine in Exertional Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Randomized Placebo-Controlled Clinical Trial." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2063.

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