Journal articles on the topic 'MDSC, pancreatic ductal adenocarcinoma, humanized mice'
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Rambuscheck, C., P. Metzger, C. Hörth, R. Hennel, S. Bärthel, C. Falcomatà, K. Lauber, et al. "P03.11 Exploring tumor-intrinsic factors regulating the recruitment of myeloid-derived suppressor cells (MDSC) in pancreatic ductal adenocarcinoma." Journal for ImmunoTherapy of Cancer 8, Suppl 2 (October 2020): A26.2—A27. http://dx.doi.org/10.1136/jitc-2020-itoc7.50.
Full textMahadevan, Daruka, Ritu Pandey, Yuliang Chen, Jacob Essif, and Aisha Al-Khinji. "Oncogenic roles of CEACAM6 in pancreatic ductal adenocarcinoma." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e16744-e16744. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e16744.
Full textMetzger, Philipp, Sabrina V. Kirchleitner, Daniel F. R. Boehmer, Christine Hörth, Angelika Eisele, Steffen Ormanns, Matthias Gunzer, et al. "Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model." Cancer Immunology, Immunotherapy 69, no. 10 (May 24, 2020): 2101–12. http://dx.doi.org/10.1007/s00262-020-02605-9.
Full textChoueiry, Fouad, Molly Torok, Reena Shakya, Kriti Agrawal, Anna Deems, Brooke Benner, Alice Hinton, et al. "CD200 promotes immunosuppression in the pancreatic tumor microenvironment." Journal for ImmunoTherapy of Cancer 8, no. 1 (June 2020): e000189. http://dx.doi.org/10.1136/jitc-2019-000189.
Full textCappello, Paola, Moitza Principe, Michelle Samuel Chattaragada, Roberta Curto, Daniele Giordano, Cecilia Roux, and Francesco Novelli. "The surface alpha-enolase targeting as a novel immunotherapeutical strategy for pancreatic cancer." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 75.20. http://dx.doi.org/10.4049/jimmunol.196.supp.75.20.
Full textArnoletti, Juan Pablo, Joseph Reza, Armando Rosales, Alberto Monreal, Na’im Fanaian, Suzanne Whisner, Milan Srivastava, et al. "Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation." PLOS ONE 17, no. 3 (March 22, 2022): e0265725. http://dx.doi.org/10.1371/journal.pone.0265725.
Full textBianchi, Anna, Iago De Castro Silva, Nilesh U. Deshpande, Siddharth Mehra, Samara Singh, Austin R. Dosch, Vanessa T. Garrido, et al. "Abstract 2513: MDSC-derived TNF is a novel regulator of T-cell dysfunction in pancreatic cancer." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2513. http://dx.doi.org/10.1158/1538-7445.am2022-2513.
Full textWen, Hui-Ju, Jacee Moore, Erick Davis, Daniel Long, Justin Lee, Brian Devorkin, and Howard Crawford. "Abstract B080: Disruption of ADAM17-dependent cellular crosstalk inhibits tumor progression of pancreatic ductal adenocarcinoma." Cancer Research 82, no. 22_Supplement (November 15, 2022): B080. http://dx.doi.org/10.1158/1538-7445.panca22-b080.
Full textWen, Hui-Ju, and Howard Crawford. "Abstract 341: Disruption of cellular crosstalk by blockage of ADAM17 inhibits tumor progression of pancreatic ductal adenocarcinoma." Cancer Research 82, no. 12_Supplement (June 15, 2022): 341. http://dx.doi.org/10.1158/1538-7445.am2022-341.
Full textFulton, Alexander J. P., Kourosh Saeb-Parsy, and Bristi Basu. "Abstract A074: Developing a novel in vivo model of pancreatic ductal adenocarcinoma using primary tumor samples and humanised mouse models." Cancer Research 82, no. 22_Supplement (November 15, 2022): A074. http://dx.doi.org/10.1158/1538-7445.panca22-a074.
Full textThomas, Justin, Molly Torok, Kriti Agrawal, Trang Vu, Alyssa Castillo, Min Chen, Bryan Remaily, et al. "678 The neonatal Fc receptor is elevated in monocyte-derived immune cells in pancreatic cancer." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A706. http://dx.doi.org/10.1136/jitc-2021-sitc2021.678.
Full textThomas, Justin, Molly A. Torok, Kriti Agrawal, Timothy Pfau, Trang T. Vu, Justin Lyberger, Hsiaochi Chang, et al. "The Neonatal Fc Receptor Is Elevated in Monocyte-Derived Immune Cells in Pancreatic Cancer." International Journal of Molecular Sciences 23, no. 13 (June 25, 2022): 7066. http://dx.doi.org/10.3390/ijms23137066.
Full textMukherjee, Debasmita, Lena Bercz, Liliana D’Alesio, Jessica Wedig, Timothy Pfau, Molly Torok, Shrina Jasani, and Thomas A. Mace. "Abstract B077: Tomatidine targets ATF4-dependent signaling to limit pancreatic cancer in the tumor microenvironment." Cancer Research 82, no. 22_Supplement (November 15, 2022): B077. http://dx.doi.org/10.1158/1538-7445.panca22-b077.
Full textDeshpande, Nilesh, Anna Bianchi, Iago De Castro Silva, Vanessa Garrido, Siddharth Mehra, Samara Singh, Ifeanyichukwu Ogobuiro, Nagaraj Nagathihalli, Nipun B. Merchant, and Jashodeep Datta. "Abstract C031: Targeting granulocytic MDSC-derived inflammasome activation to overcome stromal inflammation in pancreatic cancer." Cancer Research 82, no. 22_Supplement (November 15, 2022): C031. http://dx.doi.org/10.1158/1538-7445.panca22-c031.
Full textBoda, Akash, Casey Ager, Kimal Rajapakshe, Spencer Lea, Maria Emilia Di Francesco, Philip Jones, and Michael Curran. "758 High-potency synthetic STING agonists rewire the myeloid stroma in the tumour microenvironment to amplify immune checkpoint blockade efficacy in refractory pancreatic ductal adenocarcinoma." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A793. http://dx.doi.org/10.1136/jitc-2021-sitc2021.758.
Full textVenepalli, Neeta K., Chintan Chandrakant Gandhi, Howard Ozer, Dominic Ho, Yang Lu, Hui Xie, Stephanie A. Berg, et al. "Phase Ib study of PGG beta glucan in combination with anti-MUC1 antibody (BTH1704) and gemcitabine for the treatment of advanced pancreatic cancer." Journal of Clinical Oncology 33, no. 3_suppl (January 20, 2015): TPS493. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.tps493.
Full textKim, Hyejung, Emanuela Guerra, Eunji Baek, Yeojin Jeong, Hyogeun You, Byeongjun Yu, Taeik Jang, Alberti Saverio, Chul-Woong Chung, and Changsik Park. "Abstract 328: LCB84, a TROP2-targeted ADC, for treatment of solid tumors that express TROP-2 using the hu2G10 tumor-selective anti-TROP2 monoclonal antibody, a proprietary site-directed conjugation technology and plasma-stable tumor-selective linker chemistry." Cancer Research 82, no. 12_Supplement (June 15, 2022): 328. http://dx.doi.org/10.1158/1538-7445.am2022-328.
Full textZhang, Wei, Michel’le Wright, Moeez Rathore, Ali Vaziri-Gohar, Jordan Winter, and Rui Wang. "Abstract PO-131: The role of liver endothelium on pancreatic cancer growth." Cancer Research 81, no. 22_Supplement (November 15, 2021): PO—131—PO—131. http://dx.doi.org/10.1158/1538-7445.panca21-po-131.
Full textKoch, Elizabeth, Max London, Amy Berkley, Allison Nixon, Sean Phippen, Kerry White, Amanda Hanson, Samuel Cooper, Christopher Harvey, and Michael Briskin. "Abstract 388: AI/ML-driven discovery of a novel proteoglycan for precision targeting of ADCs for disruption of stromal barriers and direct anti-tumor activity." Cancer Research 82, no. 12_Supplement (June 15, 2022): 388. http://dx.doi.org/10.1158/1538-7445.am2022-388.
Full textLewis, Clayton S., Aniruddha Karve, Kateryna Matiash, Timothy Stone, Jingxing Li, Jordon K. Wang, Henri H. Versteeg, et al. "A First-In-Class, Humanized Antibody Targeting Alternatively Spliced Tissue Factor: Preclinical Evaluation in an Orthotopic Model of Pancreatic Ductal Adenocarcinoma." Frontiers in Oncology 11 (July 29, 2021). http://dx.doi.org/10.3389/fonc.2021.691685.
Full textBaart, Victor M., Labrinus van Manen, Shadhvi S. Bhairosingh, Floris A. Vuijk, Luisa Iamele, Hugo de Jonge, Claudia Scotti, et al. "Side-by-Side Comparison of uPAR-Targeting Optical Imaging Antibodies and Antibody Fragments for Fluorescence-Guided Surgery of Solid Tumors." Molecular Imaging and Biology, October 12, 2021. http://dx.doi.org/10.1007/s11307-021-01657-2.
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