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1

Jin, Yoonhee. "Energetics and mechanism of multidrug transport by the MATE transporter NorM from Vibrio cholerae." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648473.

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2

Pengelly, Jasper John Lobl Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Molecular characterisation of membrane transporters associated with saxitoxin biosynthesis in cyanobacteria." Publisher:University of New South Wales. Biotechnology & Biomolecular Sciences, 2008. http://handle.unsw.edu.au/1959.4/41429.

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The release of the neurotoxic alkaloid saxitoxin by cyanobacterial cells was previously thought to occur primarily after cell lysis, yet recent evidence also suggests active toxin export by membrane transporters. Transporter proteins associated with STX biosynthesis in Cylindrospermopsis raciborskii T3 (sxtF and sxtM) and Anabaena circinalis 131C (naDt) were predicted to be involved in the export of STX from cyanobacterial cells. The main aim of this project was to characterise the transporters associated with STX biosynthesis, by investigation of their genetic prevalence, functional substra
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3

Zakrzewska, Sandra [Verfasser], Hartmut [Akademischer Betreuer] Michel, Klaas Martinus [Gutachter] Pos, and Hartmut [Gutachter] Michel. "Structural and functional characterization of a MATE family multidrug resistance transporter from "Pyrococcus furiosus" / Sandra Zakrzewska ; Gutachter: Klaas Martinus Pos, Hartmut Michel ; Betreuer: Hartmut Michel." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2020. http://d-nb.info/1208033042/34.

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4

Chedik, Lisa. "Nature et conséquences des interactions entre transporteurs membranaires et pesticides." Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1B035/document.

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Les pyréthrinoïdes et les organophosphorés sont des pesticides très utilisés, à l’origine d’une imprégnation forte de la population, exposée à ces contaminants principalement via l’alimentation. De plus en plus d’études scientifiques suggèrent des liens entre l’exposition à ces composés et des maladies chroniques ou des troubles du développement de l’enfant. Paradoxalement, leur devenir biologique chez l’homme est mal connu. Certaines études suggèrent que ces insecticides sont susceptibles d’intéragir avec les transporteurs membranaires ABC et SLC, protéines localisées au niveau d’interfaces h
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Raturi, Sagar. "Energetics and structural aspects of cation-coupled drug transport by NorM multidrug transporters." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/284914.

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NorM multidrug transport proteins belong to the multiple antibiotics and toxins extrusion (MATE) family of secondary active transporters. Members of this family are present across all species including bacteria, plants and humans. In bacteria, their over-expression can lead to antibiotic resistance, whereas in the human body, the transporters can alter the plasma levels of drugs. NorM proteins are therefore relevant for the pharmacokinetic properties of drugs. Previously, NorM from Vibrio cholerae (NorM-VC) was shown to export drug (ethidium) in an antiport reaction that is coupled to the simu
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Hoang, Thi Thanh Minh. "Caractérisation moléculaire du transport du fer dans la graine : clonage de transporteurs d'efflux d'ascorbate." Thesis, Montpellier, SupAgro, 2015. http://www.theses.fr/2015NSAM0034.

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Le fer (Fe) est un micro-élément essentiel pour les plantes. Nous avons récemment montré que l'ascorbate joue un rôle central dans le transport de Fe dans lesgrainesen participant à la réduction de Fe3+ pour l'absorption de Fe2+. En outre, l'activité de l'efflux d’ascorbate à la surface de l'embryon est cruciale dans ce processus. Nous avons utilisé une stratégie de complémentation de levure pour isoler les transporteurs d'efflux d’ascorbate, en exprimant une banqued'ADNc d'Arabidopsis dans le mutant perte de fonction de la réductase ferrique, Δfre1, incapable de se développer en carence en Fe
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Afonso, José Leonardo Marcelo. "Potenciais impactos socioeconômicos e ambientais na ativação de trem turístico na Zona da Mata Mineira." Universidade Federal de Juiz de Fora (UFJF), 2017. https://repositorio.ufjf.br/jspui/handle/ufjf/4667.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-05-25T17:42:04Z No. of bitstreams: 1 joseleonardomarceloafonso.pdf: 6592803 bytes, checksum: 3617e6e66ca362755435b767e4a44913 (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-05-26T12:00:32Z (GMT) No. of bitstreams: 1 joseleonardomarceloafonso.pdf: 6592803 bytes, checksum: 3617e6e66ca362755435b767e4a44913 (MD5)<br>Made available in DSpace on 2017-05-26T12:00:32Z (GMT). No. of bitstreams: 1 joseleonardomarceloafonso.pdf: 6592803 bytes, checksum: 3617e6e66ca362755435b767e4a44913 (MD5)
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Negreiros, Rísia Lopes. "Caracterização e análise da rede de movimento de bovinos no Estado de Mato Grosso." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-12062012-144132/.

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O objetivo deste trabalho é analisar os dados de movimentação de bovinos, gerando informações úteis à vigilância epidemiológica do Estado de Mato Grosso. Analisou-se, para 2007, a distribuição de rebanhos nas propriedades, a movimentação por ecossistema de origem e destino, por finalidade (engorda, abate ou reprodução), e por época do ano. Observou-se que 81,54% do rebanho está concentrados em 20% das propriedades, indicando a existência de poucas propriedades com intensa comercialização para abate, engorda ou reprodução e muitas propriedades com pouca comercialização. Das 72.149 propriedade
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Alasmari, Fawaz Fayez. "Effects of Beta-Lactam Antibiotics on Cystine /Glutamate Exchanger Transporter and Glutamate Transporter 1 Isoforms as well as Ethanol Drinking Behavior in Male P Rats." University of Toledo Health Science Campus / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=mco1435826676.

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Oliveira, Nilton Marques de. "Transporte e localização da agroindústria da soja no estado de Mato Grosso." Universidade Federal de Viçosa, 2003. http://www.locus.ufv.br/handle/123456789/8999.

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Submitted by Marco Antônio de Ramos Chagas (mchagas@ufv.br) on 2016-11-01T09:55:07Z No. of bitstreams: 1 texto completo.pdf: 2194246 bytes, checksum: 79af4b90e3bdc533521382733d5c1ddf (MD5)<br>Made available in DSpace on 2016-11-01T09:55:07Z (GMT). No. of bitstreams: 1 texto completo.pdf: 2194246 bytes, checksum: 79af4b90e3bdc533521382733d5c1ddf (MD5) Previous issue date: 2003-02-03<br>O objetivo geral deste trabalho foi identificar e analisar as rodovias na alocação modal ótima que minimizem os custos de transportes entre as áreas de produção à agroindústria e determinar a localização ót
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Denegri, Miasta Carlo Ítalo Gabriel. "Diseño de sistema de nivelación automática para transporte de emergencia en el planeta Marte." Bachelor's thesis, Pontificia Universidad Católica del Perú, 2021. http://hdl.handle.net/20.500.12404/20301.

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Uno de los sueños del ser humano siempre ha sido viajar hacia las estrellas y visitar otros planetas. El deseo de alcanzar destinos más allá de la Tierra ha impulsado el desarrollo de tecnologías innovadoras como el GPS [1] o el descubrimiento del efecto de la micro-gravedad en el decrecimiento de las células del cáncer [2]. Hace un siglo, la comunidad científica se preguntaba cómo viajar al espacio; en cambio, ahora, se pregunta si una misión espacial tripulada llegará a Marte antes del 2030. Uno de los hitos de la carrera espacial ocurrió el 12 de abril de 1961 cuando el cosmonauta ruso Yuri
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Tardelli, Bruno Leonardo Silva. "O escoamento de soja de Mato Grosso para exportação : uma análise de integração espacial de mercados e dos impactos da redução dos custos de transporte." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/79121.

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Esta dissertação está dividida em dois artigos que explorarão os custos internos de transporte da soja no Brasil. Os artigos estudam as condições de deficiência de escoamento da soja brasileira para exportação. Neste sentido, o primeiro artigo avalia os gargalos existentes no trajeto entre o estado do Mato Grosso – maior produtor brasileiro –, e o porto de Santos – maior ponto de exportação da soja proveniente do Mato Grosso. Os resultados indicam que a precariedade rodoviária do estado do Mato Grosso e o excessivo uso do modal rodoviário poderiam representar significativos entraves à competit
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13

Lima, Ronei Coelho de. "O uso corporativo do território pelo agronegócio e a questão da logística de transportes em Mato Grosso." reponame:Repositório Institucional da UnB, 2015. http://dx.doi.org/10.26512/2015.10.T.19271.

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Tese (doutorado)—Universidade de Brasília, Instituto de Ciências Humanas, Departamento de Geografia, Programa de Pós Graduação em Geografia, 2015.<br>Submitted by Raquel Viana (raquelviana@bce.unb.br) on 2015-11-23T20:27:49Z No. of bitstreams: 1 2015_RoneiCoelhodeLima.pdf: 8158042 bytes, checksum: 18a6b9e7c3ed1ea7fdee274cebeb9e1f (MD5)<br>Approved for entry into archive by Marília Freitas(marilia@bce.unb.br) on 2016-01-25T12:58:03Z (GMT) No. of bitstreams: 1 2015_RoneiCoelhodeLima.pdf: 8158042 bytes, checksum: 18a6b9e7c3ed1ea7fdee274cebeb9e1f (MD5)<br>Made available in DSpace on 2016-01-25T
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Martinez-Guerrero, Lucy Jazmin. "Substrate Influence on Ligand Interaction with the Human Multidrug And Toxin Extruder (MATE)." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/593494.

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Organic cation (OC) secretion across renal proximal tubules (RPTs) involves basolateral OCT2- mediated uptake from the blood, followed by apical MATE1/2-mediated efflux into the tubule filtrate. Whereas OCT2 supports electrogenic OC uniport, MATE is an OC/H exchanger. OCs make up ~40% of all prescribed drugs and renal secretion plays a major role in clearing them. This study looked at two aims with the intent of resolving two outstanding issues dealing with the mechanism of MATE-mediated OC transport. First: Understanding the nature of intracellular sequestration of OC in cells that express hM
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15

Larsson, Felix, and Robin Linna. "An Analysis of Passenger Demand Forecast Evaluation Methods." Thesis, Linköpings universitet, Kommunikations- och transportsystem, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-139942.

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In the field of aviation forecasting is used, among other things, to determine the number of passengers to expect for each flight. This is beneficial in the practice of revenue management, as the forecast is used as a base when setting the price for each flight. In this study, a forecast evaluation has been done on seven different routes with a total of 61 different flights, using four different methods. These are: Mean Absolute Scaled Error (MASE), Mean Absolute Percentage Error (MAPE), Tracking Signal, and a goodness of fit test to determine if the forecast errors are normally distributed. T
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16

Astorga, Bethzaida. "Multidrug And Toxin Extrusion's (MATE) Role in Renal Organic Cation Secretion." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/205470.

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Organic cations (OCs) make up ~40% of all prescribed drugs and renal secretion plays a major role in clearing these (and other OCs), from the plasma. The active and rate-limiting step of renal OC secretion is mediated by luminal OC/H+ exchange, the molecular basis of which is suspected to involve two homologous transport proteins, Multidrug And Toxin Extruders 1&2-K (MATE1 and MATE2-K). This study has two aims to resolve outstanding issues dealing with the mechanism of MATE-mediated OC transport: (Aim 1) develop predictive models of ligand interaction with hMATE1; (Aim 2) establish the kine
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17

Aal-Aaboda, Munaf Sabah. "Glutamate Transporter 1 and Cystine-Glutamate Antiporter as Potential Targets for Attenuating Alcohol Consumption in Male P Rats." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1403010118.

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18

Araujo, Juliana Aragao de. "Modelagem matem?tica para o transporte de part?culas sujeitas a m?ltiplos mecanismos de reten??o." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13034.

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Made available in DSpace on 2014-12-17T14:09:18Z (GMT). No. of bitstreams: 1 JulianaAA_TESE.pdf: 2312979 bytes, checksum: 31c1a19cbf37d537febd576ec54e5eb2 (MD5) Previous issue date: 2013-09-13<br>Discrepancies between classical model predictions and experimental data for deep bed filtration have been reported by various authors. In order to understand these discrepancies, an analytic continuum model for deep bed filtration is proposed. In this model, a filter coefficient is attributed to each distinct retention mechanism (straining, diffusion, gravity interception, etc.). It was shown that t
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Julião, Maria Heloisa Moreno. "Genomic identification of MATE, ABC, and MFS transporters in Citrus sinensis and expression analysis of Citrus species interacting with Xanthomonas citri subsp. citri /." Jaboticabal, 2020. http://hdl.handle.net/11449/192658.

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Orientador: Alessandro de Mello Varani<br>Resumo: As plantas como organismos sésseis requerem a síntese e o acúmulo de uma ampla variedade de moléculas envolvidas no crescimento, desenvolvimento e processos relacionados à defesa. Os transportadores Proteínas de Extrusão Multi- Antimicrobianas (MATE), Cassette de Ligação de ATP (ABC) e Superfamília dos Facilitadores Maioritários (MFS) são as principais famílias de transportadores de membrana em plantas, desempenhando um papel central nos processos relacionados à defesa nas interações planta-patógenos. Por exemplo, protegem as células das espéci
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Weintraut, Melodie Lynn. "Small Intestinal Transporters in Two Species of Galliformes: Male and Female Turkey (Meleagris gallopavo) and Chicken (Gallus gallus)." Thesis, Virginia Tech, 2015. http://hdl.handle.net/10919/73559.

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The objective of the first study was to characterize amino peptidase N (APN), peptide (PepT1), amino acid (ASCT1, bo,+AT, CAT1, EAAT3, LAT1, y+LAT2), and sugar transporter expression (GLUT2, GLUT5, SGLT1) in the small intestine of male and female turkeys. Small intestine samples were collected during embryonic development (E21, E24) and DOH. In a separate experiment during post-hatch development (DOH, D7, D14, D21, D28). APN, bo,+AT, PepT1, y+LAT2, GLUT5 and SGLT1 were expressed most on DOH. Post-hatch, all genes except GLUT2 and SGLT1 were expressed greater in females than males. SGLT1 was ex
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Carmo, Márcio Teoro do [UNESP]. "Estudo do fluido folicular, transporte, recuperaçao e maturação de oócitos em éguas superovuladas com estrato de pituitária equina." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/105971.

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Made available in DSpace on 2014-06-11T19:35:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2007Bitstream added on 2014-06-13T20:06:45Z : No. of bitstreams: 1 carmo_mt_dr_botfmvz.pdf: 1969502 bytes, checksum: 198972891441c6a64f8bf48146e2e8b1 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>A fêmea da espécie eqüina é considerada monovulatória sazonal, o que é ator limitante a produção de embriões ao longo do ano. Esta limitação poderia inimizada se houvesse uma resposta superovulatória eficiente em melhorar a ção de embriões. Protocolos mais recentes desenvolvi
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OLIVEIRA, Ademir Machado De. "Impacto econômico de investimentos em infraestrutura de transporte rodoviário: avaliação do Programa Estradeiro nos municípios do estado de Mato Grosso." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/18006.

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Submitted by Irene Nascimento (irene.kessia@ufpe.br) on 2016-10-18T17:48:54Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Tese_Dr_ Ademir_versão_final.pdf: 3702988 bytes, checksum: eb2236ff9ca649ee1fb4cb295cf4f196 (MD5)<br>Made available in DSpace on 2016-10-18T17:48:54Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Tese_Dr_ Ademir_versão_final.pdf: 3702988 bytes, checksum: eb2236ff9ca649ee1fb4cb295cf4f196 (MD5) Previous issue date: 2016-05-31<br>CAPES<br>Este estudo analisa os imp
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Gomes, Patricia Morais. "Transporte e reprodução do espaço: o papel da Estrada de Ferro Central do Brasil na dinâmica do espaço urbano de Santos Dumont." Universidade Federal de Juiz de Fora (UFJF), 2013. https://repositorio.ufjf.br/jspui/handle/ufjf/4090.

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Schlunk, Ines [Verfasser], Erika [Akademischer Betreuer] Kothe, Axel A. [Akademischer Betreuer] Brakhage, and Uwe [Akademischer Betreuer] Nehls. "Charakterisierung des MATE-Transporters Mte1 und Etablierung eines Transformationssystems für den Ektomykorrhiza-Pilz Tricholoma vaccinum / Ines Schlunk. Gutachter: Erika Kothe ; Axel A. Brakhage ; Uwe Nehls." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2012. http://d-nb.info/1018652949/34.

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Carmo, Márcio Teoro do. "Estudo do fluido folicular, transporte, recuperaçao e maturação de oócitos em éguas superovuladas com estrato de pituitária equina /." Botucatu : [s.n.], 2007. http://hdl.handle.net/11449/105971.

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Resumo: A fêmea da espécie eqüina é considerada monovulatória sazonal, o que é "ator limitante a produção de embriões ao longo do ano. Esta limitação poderia inimizada se houvesse uma resposta superovulatória eficiente em melhorar a ção de embriões. Protocolos mais recentes desenvolvidos em nosso atório utilizando-se o Extrato de Pituitária Eqüina (EPE) têm permitido uma esposta superovulatória. Contudo o número de embriões recuperados ainda sido inferior ao das ovulações, em conseqüência de fatores ainda não inados. O presente estudo teve por objetivo: verificar se o tratamento com o - admini
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Dirami, Thassadite. "Le transporteur anionique TAT1 (SLC26A8) : rôle physiologique et implication dans les asthénozoospermies humaines." Thesis, Paris 5, 2012. http://www.theses.fr/2012PA05T050/document.

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La protéine TAT1 (Testis Anion Transporter 1 ; SLC26A8) appartient à la famille des SLC26, une famille de transporteurs d’anions qui contribuent dans différents épithelia à l’homéostasie cellulaire. La protéine TAT1 s’exprime exclusivement dans les cellules germinales mâles, chez l’homme et chez la souris. Sur le spermatozoïde mature, la protéine TAT1 est localisée à la jonction des pièces intermédiaire (PI) et principale (PP) du flagelle, au niveau de l’annulus, une structure en forme d’anneau composée de différents polymères de Septines (1, 4, 6, 7 et 12).Le modèle murin d’invalidation du gè
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Dalpiaz, Diego. "Simula??o num?rica de transporte e dep?sito de sedimentos em suspens?o em canal inclinado." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2014. http://tede2.pucrs.br/tede2/handle/tede/3270.

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Made available in DSpace on 2015-04-14T13:59:11Z (GMT). No. of bitstreams: 1 462338.pdf: 6932658 bytes, checksum: 002a8671d2441b25bba6d1226ae0b910 (MD5) Previous issue date: 2014-08-29<br>Gravity currents begin when two fluid bodies, with different densities, collides one against other, starting a relative movement in both, being these processes responsible for the transport of sediment from the continental shelf into the deep ocean and the marine construction relief. When the density of sediments transported by rivers exceeds the density of the ambient fluid, it can plunge and form a submer
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Kato, Tomoko. "Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263549.

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Graf, Justin T. "Membrane associated transporter protein gene (SLC45A2) and the genetic basis of normal human pigmentation variation." Queensland University of Technology, 2008. http://eprints.qut.edu.au/25913/.

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This work is concerned with the genetic basis of normal human pigmentation variation. Specifically, the role of polymorphisms within the solute carrier family 45 member 2 (SLC45A2 or membrane associated transporter protein; MATP) gene were investigated with respect to variation in hair, skin and eye colour ― both between and within populations. SLC45A2 is an important regulator of melanin production and mutations in the gene underly the most recently identified form of oculocutaneous albinism. There is evidence to suggest that non-synonymous polymorphisms in SLC45A2 are associated with normal
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Webber, J. Beau W., Philip Bland, John H. Strange, Ross Anderson, and Bahman Tohidi. "Why you can’t use water to make cryoporometric measurements of the pore size distributions in meteorites – or in high iron content clays, rocks or concrete." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-191847.

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Many porous materials have high susceptibility magnetic gradients in the pores, due to the presence of iron or other magnetic materials. Thus if probe liquids are placed in the pores they exhibit fast decaying signals with a short T2*. Usually the actual T2 of the liquids is also reduced, due the presence of paramagnetic ions in the pore walls. The usual solution in NMR is to measure an echo (or echo train) at short times. However, recent work [J. Phys.: Condens. Matter 19, 415117, 2007.] has shown that water/ice systems near a pore wall form rotator phase plastic ice, with T2 relaxation times
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Freeman, Elizabeth D. "Methylphenidate Conditioned Place Preference in Juvenile and Adolescent Male and Female Rats." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etd/2293.

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This investigation was an analysis of the effects of methylphenidate (MPH; trade name: Ritalin) on drug reward using the conditioned place preference (CPP) behavioral paradigm in a rodent model and underlying mechanisms of this effect. Animals were conditioned in adolescence from postnatal day (P)33-39) or P44-49 with saline, 1 or 5 mg/kg MPH. Rats administered 5 mg/kg but not 1 mg/kg MPH, resulted in a significant preference that was more robust in younger male adolescent rats. The 5 mg/kg dose of MPH also resulted in a significant decrease of the dopamine transporter in both the nucleus accu
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Johansson, Jimmy. "Mechanical processing for improved products made from Swedish hardwood." Doctoral thesis, Växjö : Växjö University Press, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-2457.

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Fonseca, Lorena Coutinho Nery da 1981. "Transporte de pólen de espécies ornitófilas e energia disponível para beija-flores em área de Mata Atlântica, Núcleo Picinguaba/PESM, Ubatuba, SP." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/315378.

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Orientador: Marlies Sazima<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-20T00:54:41Z (GMT). No. of bitstreams: 1 Fonseca_LorenaCoutinhoNeryda_D.pdf: 15688849 bytes, checksum: 5ab648e9c0a851952dff287bd487d46e (MD5) Previous issue date: 2012<br>Resumo: O estudo das relações entre beija-flores e plantas, do fluxo polínico entre as espécies polinizadas e da área utilizada por estas aves é importante para melhor entendimento dos processos evolutivos que levaram a estas interações, além de fornecer subsídios para a conservaçã
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34

Finnskog, Erik, and Fabian Furberg. "Effektivisering av materialgenomflöde för ”Make To Order”- Företag." Thesis, Tekniska Högskolan, Jönköping University, JTH, Logistik och verksamhetsledning, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-46364.

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Purpose – The purpose of this study is to examine the material flow and production effectiveness at a Make to Order companies. To answer the purpose two research questions have been formed; What challenges do MTO companies have regarding throughput? Which tools and standards are suitable to an MTO companies for an increased throughput? Method – The study is based on an abductive approach in which the authors have chosen to use triangulation to answer the purpose of the study. The data collection methods used are literature studies, interviews, observations and document studies. The authors
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Webber, J. Beau W., Philip Bland, John H. Strange, Ross Anderson, and Bahman Tohidi. "Why you can’t use water to make cryoporometric measurements of the pore size distributions in meteorites – or in high iron content clays, rocks or concrete." Diffusion fundamentals 10 (2009) 3, S. 1-3, 2009. https://ul.qucosa.de/id/qucosa%3A14092.

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Many porous materials have high susceptibility magnetic gradients in the pores, due to the presence of iron or other magnetic materials. Thus if probe liquids are placed in the pores they exhibit fast decaying signals with a short T2*. Usually the actual T2 of the liquids is also reduced, due the presence of paramagnetic ions in the pore walls. The usual solution in NMR is to measure an echo (or echo train) at short times. However, recent work [J. Phys.: Condens. Matter 19, 415117, 2007.] has shown that water/ice systems near a pore wall form rotator phase plastic ice, with T2 relaxation times
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36

Đorđije, Doder. "Uticaj prekidnih režima na fenomene prenosa mase i toplote pri sušenju materijala sfernog oblika." Phd thesis, Univerzitet u Novom Sadu, Fakultet tehničkih nauka u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=110746&source=NDLTD&language=en.

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Prikazana je procedura modelovanja prekidnog sušenja materijala sfernog oblika u tankom sloju, nakon čega je pokrenuta računarska simulacija procesa na osnovu predloženog modela. Zatim, odrađeno je eksperimantalno istraživanje, za šta su korišćeni svježe ubrani orasi u ljusci, bez komine. Nakon što je statistički potvrđena pouzdanost modela, on je iskorišćen kao baza formiranje modela za simulaciju sušenja u debelom sloju. Posle toga su urađeni eksperimenti i za druge materijale različitih osobina (krompir, bundeva i kestenje), da bi se izveli zaključci o mogućnosti energetske uštede u procesi
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37

Freitas, Helber Custódio de. "A influência dos transportes advectivos na estimatitiva do balanço de CO2 do ecossistema: um estudo de caso para a mata atlântica com uso de técnicas micrometeorológicas." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/91/91131/tde-17042012-145144/.

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Para este trabalho, foram realizadas observações de variáveis climáticas e medidas de fluxo de carbono, durante o período de 2008 a 2010, sobre uma floresta de mata atlântica, buscando estimar o balanço de carbono neste sítio experimental, com o objetivo de melhor compreender as trocas de CO2 entre esta floresta e a atmosfera. Para tanto, foram utilizadas técnicas micrometeorológicas de vórtices turbulentos associadas a medidas de transportes advectivos. Este estudo investigou uma área de características singulares, de intensos gradientes topográficos, na cidade de São Luiz do Paraitinga, esta
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38

GANTI, VAISHNAVI. "A PHARMACOKINETIC BASED STUDY TO BETTER UNDERSTAND THE REPORTED COGNITIVE DEFICITS FOR 5-FLUOROURACIL AND METHOTREXATE IN MALE SWISS-WEBSTER MICE." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/262852.

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Pharmaceutical Sciences<br>Ph.D.<br>Chemotherapy related neurotoxicity is the decrease in cognitive function observed in patients receiving chemotherapy for breast cancer. For cancers with higher survival rates such as breast cancer, quality of life for patients after treatment cessation is a major concern. In studies performed in our laboratory, we reported cognitive deficiencies in male Swiss-Webster mice on administering 75 mg/kg 5-FU with 3.2 mg/kg MTX and these deficits were significantly greater than groups receiving either drug alone or in another higher dose combination. The probable m
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Frölin, Albin, and Carl-Marcus Bergman. "Effektivisering av ett internt materialflöde : En studie av ett internt materialflöde där strategin är make-to-order och produktionsupplägget är funktionellt." Thesis, Jönköping University, JTH, Logistik och verksamhetsledning, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-53984.

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40

Bernot, Marc. "Transport optimal et irrigation." Phd thesis, École normale supérieure de Cachan - ENS Cachan, 2005. http://tel.archives-ouvertes.fr/tel-00132078.

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L'objet de cette thèse est de modéliser et d'étudier des structures d'irrigation telles les nervures des feuilles, réseau sanguin, poumons,etc. Un modèle généralisant le problème de Gilbert Steiner est introduit ; on étudie alors les propriétés d'existence, de stabilité et régularité. Des algorithmes sont alors proposés pour la simulation.
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41

Andrade, Ernani Nery de [UNESP]. "Avaliação de procedimentos no manejo pré-abate de bovinos e bubalinos no Pantanal Sul Mato-Grossense." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/96629.

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Made available in DSpace on 2014-06-11T19:28:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-02-09Bitstream added on 2014-06-13T19:26:34Z : No. of bitstreams: 1 andrade_en_me_botfmvz.pdf: 582436 bytes, checksum: 1e1a74583792eb25b0a3ffbf974bd242 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Universidade Estadual Paulista (UNESP)<br>O objetivo deste estudo foi avaliar a influência do transporte fluvial na incidência de lesões tissulares em carcaças de bovinos abatidos no Pantanal Sul Mato-grossense, por meio da quantificação do número e tamanho das
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42

Fan, Yan, Ping Ping Chen, Ying Li та ін. "Corticosterone Administration up-Regulated Expression of Norepinephrine Transporter and Dopamine Β-Hydroxylase in Rat Locus Coeruleus and Its Terminal Regions". Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/955.

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Stress has been reported to activate the locus coeruleus (LC)-noradrenergic system. In this study, corticosterone (CORT) was orally administrated to rats for 21 days to mimic stress status. In situ hybridization measurements showed that CORT ingestion significantly increased mRNA levels of norepinephrine transporter (NET) and dopamine β-hydroxylase (DBH) in the LC region. Immunofluorescence staining and western blotting revealed that CORT treatment also increased protein levels of NET and DBH in the LC, as well as NET protein levels in the hippocampus, the frontal cortex and the amygdala. Howe
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43

Andrade, Ernani Nery de 1976. "Avaliação de procedimentos no manejo pré-abate de bovinos e bubalinos no Pantanal Sul Mato-Grossense /." Botucatu : [s.n.], 2007. http://hdl.handle.net/11449/96629.

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Orientador: Roberto de Oliveira Roça<br>Banca: Mateus Jose Rodrigues Paranhos da Costa<br>Banca: Germano Francisco Biondi<br>Resumo: O objetivo deste estudo foi avaliar a influência do transporte fluvial na incidência de lesões tissulares em carcaças de bovinos abatidos no Pantanal Sul Mato-grossense, por meio da quantificação do número e tamanho das lesões, bem como a identificação e determinação da idade das lesões em função do tempo ocorrido e a localização dessas lesões nos principais cortes comerciais brasileiros. Apurou-se que do total de 88 carcaças avaliadas, 83 (94,3%) tiveram uma ou
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Grottker, Julia [Verfasser], Gerhard [Akademischer Betreuer] Burckhardt, Claudia [Akademischer Betreuer] Steinem, and Jürgen [Akademischer Betreuer] Brockmöller. "Expression von SLC-Transportern in Melanomzelllinien und Charakterisierung von MATE1 und OCT1 in ihrer Funktion als Zytostatikatransporter / Julia Grottker. Gutachter: Claudia Steinem ; Gerhard Burckhardt ; Jürgen Brockmöller. Betreuer: Gerhard Burckhardt." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2011. http://d-nb.info/1043939547/34.

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45

Rocha, Miriam Karla. "Otimiza??o de escalas de servi?o de tripula??es estudo de caso em uma empresa de transporte urbano na regi?o metropolitana de Natal/RN." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/15036.

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Made available in DSpace on 2014-12-17T14:53:08Z (GMT). No. of bitstreams: 1 MiriamKR_DISSERT.pdf: 394744 bytes, checksum: 86723bb7ac2b34e7cfb757711ca68d77 (MD5) Previous issue date: 2012-06-25<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>This work aims to "build" rostering urban bus crews to minimize the cost of overtime. For this purpose a mathematical model was developed based on case study in an urban transport company in the metropolitan region of Natal. This problem is usually known in the literature as the Crew Scheduling Problem (CSP) and classified as NP-hard. T
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46

Notarjacomo, Márcia Helena Borges. "Escoamento da produção de açúcar a granel do Estado de Mato Grosso do Sul destinado à exportação : um estudo de rotas e seus custos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/96381.

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O estudo trata do escoamento da produção de açúcar tendo objetivo analisar o processo de escoamento da produção de açúcar a granel do estado do Mato Grosso do Sul, destinado á exportação. Para tanto, foram estipulados objetivos específicos que correspondem aos dois artigos que constituem esse trabalho. O primeiro artigo intitulado “Escoamento da produção de açúcar a granel do Estado de Mato Grosso do Sul destinado á exportação: um estudo de rotas e seus custos,” teve a finalidade de descrever as principais rotas utilizadas e sugerindo novas alternativas de percurso para escoar a produção aos p
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47

Souza, Cristiane Santos de. "Análise molecular e estrutural da proteína ligadora de maltose (MalE) de Xanthomonas axonopodis pv. citri." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-23102009-130040/.

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A captação de maltose em bactérias é feita por um sistema transportador do tipo ABC composto por uma proteína ligadora de substrato (MalE), duas proteínas transmembrana e uma ATPase. No presente trabalho descrevemos a clonagem, expressão e análise bioquímica e estrutural da proteína MalE da bactéria fitopatogênica Xanthomonas axonopodis pv citri (Xac) O gene malE de Xac foi clonado em vetor de expressão pET28a, a proteína recombinante foi expressa em Escherichia coli e purificada por cromatografia de afinidade ao níquel. Amostras da proteína solúvel foram analisadas quanto à estrutura secundár
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48

Dantas, Klayta Benigno Ramalho. "Transporte de subst?ncias atrav?s da membrana plasm?tica: com utiliza??o de um jogo did?tico digital para alunos do ensino m?dio." PROGRAMA DE P?S-GRADUA??O EM ENSINO DE CI?NCIAS NATURAIS E MATEM?TICA, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/24021.

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Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-10-04T19:29:14Z No. of bitstreams: 1 KlaytaBenignoRamalhoDantas_DISSERT.pdf: 2222985 bytes, checksum: a81e268c2181aa4b584c325fd5f160aa (MD5)<br>Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-10-09T23:33:02Z (GMT) No. of bitstreams: 1 KlaytaBenignoRamalhoDantas_DISSERT.pdf: 2222985 bytes, checksum: a81e268c2181aa4b584c325fd5f160aa (MD5)<br>Made available in DSpace on 2017-10-09T23:33:02Z (GMT). No. of bitstreams: 1 KlaytaBenignoRamalhoDantas_DISSERT.pdf: 2222985 bytes, checksum:
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Bergel-Hayat, Ruth. "La prise en compte de variables explicatives dans les modèles de séries temporelles : application à la demande de transport et au risque routier." Phd thesis, Université Paris-Est, 2008. http://tel.archives-ouvertes.fr/tel-00432051.

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L'objet de la thèse est d'exposer une démarche méthodologique qui vise à prendre en compte, dans les modèles de séries temporelles, des effets exogènes mesurés à l'aide de variables additionnelles, et de l'illustrer par un certain nombre d'applications au secteur des transports. Dans ces applications, le pas de temps est le jour, le mois, le trimestre voire le semestre : il s'est agi de prendre en compte des effets exogènes, de nature transitoire ou de nature durable, qui se manifestent dans le court terme. La première partie de la thèse traite de la modélisation des séries temporelles. Nous s
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Peres, Karen Regina. "Emprego tópico de prostaglandina da família E ou de análogo com o intuito de acelerar a migração de embriões eqüinos para o útero e imunolocalização dos respectivos receptores." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/10/10131/tde-23012009-160254/.

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Ao contrário de outras espécies de animais domésticos, na égua os embriões descem tardiamente para o útero, creditando-se isto a uma dependência da PGE2. Conseqüentemente, são recuperados embriões que já estão em fases mais avançadas de desenvolvimento (blastocisto e blastocisto expandido) e com um tamanho que normalmente ultrapassa os 300 micrômetros quando a colheita é realizada após o 6º dia. Isto reflete em um insucesso nos protocolos de criopreservação embrionária. Em razão deste problema, testou-se a eficácia da aplicação da PGE2 por dois métodos (experimento I) e a eficácia da PGE1 e do
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