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1

Андрющенко, Володимир Вікторович, Владимир Викторович Андрющенко, and Volodymyr Viktorovych Andriushchenko. "Breast reconstruction following mastectomy." Thesis, Вид-во СумДУ, 2006. http://essuir.sumdu.edu.ua/handle/123456789/7598.

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2

Stroppa, Ana Elisa Zuliani. "Atividade eletromiografica da porção superior do musculo trapezio em mulheres mastectomizadas com sintomas depressivos." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317513.

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Orientador: Evanisi Teresa Palomari
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: A mastectomia radical é uma técnica cirúrgica muito agressiva, que causam sensações de estresse, gerando ansiedade e depressão. Esses fatores são responsáveis por desequilíbrios no organismo, como mialgias, retardo motor e fadiga. O objetivo deste trabalho foi investigar variações na atividade eletromiográfica da porção superior do músculo trapézio em mulheres mastectomizadas comparando com a interferência da sintomatologia depressiva e dominância dos MMSS. O estudo foi realizado em 23 mulheres com mastectomia radical do tipo Patey e Madden ou total simples e em 9 mulheres saudáveis portadoras ou não de sintomatologia de depressão, quantificada pelo Inventário de Depressão de Beck. Para a aquisição dos dados utilizou-se um eletromiógrafo, composto de 4 canais, com canais compostos por filtros com banda de freqüência entre 20 (FPA) e 500 Hz (FPB), placa de conversão AIO, de 12 bits de resolução e freqüência de amostragem de 1000 Hz, eletrodos bipolares ativos de Ag-Ag CI, conectados a eletrodos auto adesivos e eletrodo terra. Para análise estatística foram utilizados modelos de regressão linear. Os resultados não foram estatisticamente significantes, entretanto, houve tendências à diminuição nos valores de mediana da amplitude do sinal em RMS para o grupo mastectomizado (GM), quando comparado ao grupo controle (GC), ambos depressivo, o que sugere que a dor no local da cirurgia reduz a atividade; notou-se também, aumento desta amplitude, para o (GM) lado com cirurgia, quando comparado ao lado sem cirurgia, exceto para o (GM) sem sintomatologia depressiva, sugerindo que a postura antálgica aumente a atividade mioelétrica; para o fator psicológico e a dominância dos membros não se observou nem mesmo tendências
Abstract: The radical mastectomy is one very agrgressive technique surgical, that they cause sensations de stress, generating anxiety and depression. These factors cause some disorders in the organism, like a muscle pain, slow motor response and fatigue. This study was carried out with women who have undergone mastectomies in order to investigate possible changes in electromyographic activity of the upper trapezius muscle and compare the influence on symptoms of depression. The present study assessed bilaterally in 23 women underwent to Simple or Patey and Madden's radical mastectomies and in 9 healthy women with or without depression's symptoms, quantified by Beck Depression Inventory. The clinical records were picked up by a four-channel electromyographer. The channels were composed of filters with a frequency range between 20 (FPA) and 500 Hz (FPB), A/O conversion plate with 12 bits resolution and sampling frequency of 1000 Hz and active bipolar electrodos de Ag-Ag CI connected the adhesive electrodes and reference electrode. For statistical analysis a model of linear regression was used. Was noted tendencies in the depressive group~ thought the data were not statistically significant. It was observed the CDG had the higher median, which suggested that the pain on the site of the surgery reduces the EMG activity. On the other hand, in the MDG side with surgery, it was observed an increase in the EMG activity in comparison with the si de without surgery, which suggests that antalgic posture increases the myoelectric activity. For non-depression group, the data did not permit any conclusive data, and, in none of the cases, the dominance interfered in the myoelectric activity. Nevertheless, the data obtained was not statiscally sígnificant
Mestrado
Anatomia
Mestre em Biologia Celular e Estrutural
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3

Lemos, Talita Mayara Rossi [UNESP]. "Qualidade de vida em mulheres com câncer de mama submetidas à cirurgia conservadora e mastectomia." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/138184.

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Estudo descritivo, correlacional, com abordagem quantitativa e delineamento transversal, cujo objetivo geral foi analisar a qualidade de vida em mulheres com diagnóstico de câncer de mama, submetidas à cirurgia conservadora e à mastectomia. Os objetivos específicos, propuseram levantar as características sociodemográficas, clínicas, potenciais de adoecimento e fatores de proteção para o câncer de mama, em mulheres submetidas à cirurgia conservadora e à mastectomia, comparar as médias dos escores dos questionários European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 e BR-23, das pacientes do grupo da cirurgia conservadora e da mastectomia, e correlacionar as escalas funcionais e de sintomas dos questionários EORTC em ambos os grupos, com a escala do estado global de saúde e qualidade de vida (QLQ C-30). A pesquisa foi aprovada pelo Comitê de Ética em Pesquisa, da Faculdade de Medicina de Botucatu, parecer nº 607.171. A coleta dos dados ocorreu de maio de 2014 a maio de 2015, e a amostra total foi de 106 mulheres, sendo 66 submetidas à cirurgia conservadora, e 40 à mastectomia, acompanhadas pela equipe de mastologia do ambulatório de Ginecologia do Hospital das Clínicas de Botucatu. Para a captação dos dados foram utilizados: formulário destinado à caracterização da população, e questionários EORTC QLQ C-30 e BR-23. Pôde-se verificar que na escala funcional dos questionários EORTC, as mulheres submetidas à cirurgia conservadora apresentaram, na maioria dos domínios, médias maiores que o grupo da mastectomia. Entretanto, apenas o domínio imagem corporal apresentou-se significativo. Na escala de sintomas de ambos os questionários, o grupo da cirurgia conservadora apresentou menores médias nos domínios: dor, dispneia, insônia, constipação, dificuldade financeira e sintomas do braço e da mama, enquanto o grupo da mastectomia apresentou menores médias, nos domínios: fadiga, náusea, vômito, perda de apetite, diarreia e eventos adversos da terapia sistêmica, sendo apenas os domínios vômito e insônia significativos. Na escala do estado global de saúde e qualidade de vida, a maior média foi apresentada no grupo das mulheres submetidas à mastectomia. Quanto à correlação dos domínios dos questionários EORTC, das pacientes submetidas à cirurgia conservadora com a escala do estado global de saúde e qualidade de vida, verificou-se que os domínios que apresentaram correlação significativa foram: função física, desempenho de papéis, função emocional, função social, fadiga, dor, insônia, perda de apetite, diarreia, dificuldade financeira, eventos adversos da terapia sistêmica e sintomas do braço. Já a correlação dos domínios de ambos os questionários, no grupo das pacientes submetidas à mastectomia, com a escala de estado global de saúde e qualidade de vida, que apresentaram-se significativos foram: função emocional, insônia, dificuldade financeira e imagem corporal. Concluiu-se que, apesar do grupo da cirurgia conservadora ter apresentado médias superiores nos escores da maioria dos domínios de ambos os questionários EORTC, o grupo da mastectomia apresentou maior média na escala do estado global de saúde e qualidade de vida, demonstrando que as mulheres submetidas à mastectomia, apresentaram melhor qualidade de vida e de saúde global, após cirurgia, comparadas às submetidas à cirurgia conservadora.
This is a correlational descriptive study with a quantitative approach and cross-sectional design whose main objective is to analyze the quality of life in women with breast cancer undergoing breast-conserving surgery and mastectomy. Among the specific objectives, it was intended to raise elements such as the sociodemographic and clinical characteristics, the potential illness, and the protective factors for breast cancer in women undergoing breast-conserving surgery and mastectomy; to compare the mean scores of the European Organization for Research and Treatment of Cancer (EORTC) questionnaires QLQ-C30 and BR-23 of patients who underwent breast-conserving surgery and mastectomy; and also to correlate the functional and symptom scales of the EORTC questionnaires in both groups with the global health and quality-of-life scale (QLQ-C30). The Research Ethics Committee of Botucatu Medical School approved to perform the research with verdict No. 607.171. The data collection period was from May 2014 to May 2015, and the total sample was of 106 women. From these patients, 66 underwent breast-conserving surgery and 40 underwent mastectomy, and they were followed up by the mastology team of the Gynecology Outpatient Service of Botucatu University Hospital. Among the main results, it was verified that, in the functional scale of the EORTC questionnaires, the patients who underwent breast-conserving surgery had averages higher than those of the mastectomy group in most domains. However, only the body image domain was significant. In the symptom scale of both questionnaires, the breast-conserving surgery group had lower averages in these domains: pain, dyspnea, insomnia, constipation, financial difficulties, and arm and breast symptoms. On the other hand, the mastectomy group had lower averages in these domains: fatigue, nausea, vomiting, loss of appetite, diarrhea, and side effects of systemic therapy. The only significant domains were vomiting and insomnia. Regarding the global health and quality-of-life scale, it was found that the highest average was shown in the group of patients who underwent mastectomy. As for the correlation between the domains of the EORTC questionnaires of patients undergoing conservative surgery with the global health and quality-of-life scale, it was found that the domains showing statistically significant correlations were: physical function, role playing, emotional function, social function, fatigue, pain, insomnia, loss of appetite, diarrhea, financial difficulties, adverse events of the systemic therapy, and arm symptoms. In the correlation of the domains of both questionnaires in the group of patients undergoing mastectomy with the global health and quality-of-life scale, the significant ones were emotional function, insomnia, financial difficulties, and body image. The conclusion was that, despite the fact that the breast-conserving surgery group presented higher averages in the scores of most domains of both EORTC questionnaires, the mastectomy group had a higher average on the global health and quality-of-life scale, which demonstrates that the patients who underwent mastectomy had better quality of life and global health after the surgery compared to those who underwent breast-conserving surgery.
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Lemos, Talita Mayara Rossi. "Qualidade de vida em mulheres com câncer de mama submetidas à cirurgia conservadora e mastectomia." Botucatu, 2016. http://hdl.handle.net/11449/138184.

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Orientador: Maria de Lourdes da Silva Marques Ferreira
Resumo: Estudo descritivo, correlacional, com abordagem quantitativa e delineamento transversal, cujo objetivo geral foi analisar a qualidade de vida em mulheres com diagnóstico de câncer de mama, submetidas à cirurgia conservadora e à mastectomia. Os objetivos específicos, propuseram levantar as características sociodemográficas, clínicas, potenciais de adoecimento e fatores de proteção para o câncer de mama, em mulheres submetidas à cirurgia conservadora e à mastectomia, comparar as médias dos escores dos questionários European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 e BR-23, das pacientes do grupo da cirurgia conservadora e da mastectomia, e correlacionar as escalas funcionais e de sintomas dos questionários EORTC em ambos os grupos, com a escala do estado global de saúde e qualidade de vida (QLQ C-30). A pesquisa foi aprovada pelo Comitê de Ética em Pesquisa, da Faculdade de Medicina de Botucatu, parecer nº 607.171. A coleta dos dados ocorreu de maio de 2014 a maio de 2015, e a amostra total foi de 106 mulheres, sendo 66 submetidas à cirurgia conservadora, e 40 à mastectomia, acompanhadas pela equipe de mastologia do ambulatório de Ginecologia do Hospital das Clínicas de Botucatu. Para a captação dos dados foram utilizados: formulário destinado à caracterização da população, e questionários EORTC QLQ C-30 e BR-23. Pôde-se verificar que na escala funcional dos questionários EORTC, as mulheres submetidas à cirurgia conservadora apresentaram, na maioria dos... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: This is a correlational descriptive study with a quantitative approach and cross-sectional design whose main objective is to analyze the quality of life in women with breast cancer undergoing breast-conserving surgery and mastectomy. Among the specific objectives, it was intended to raise elements such as the sociodemographic and clinical characteristics, the potential illness, and the protective factors for breast cancer in women undergoing breast-conserving surgery and mastectomy; to compare the mean scores of the European Organization for Research and Treatment of Cancer (EORTC) questionnaires QLQ-C30 and BR-23 of patients who underwent breast-conserving surgery and mastectomy; and also to correlate the functional and symptom scales of the EORTC questionnaires in both groups with the global health and quality-of-life scale (QLQ-C30). The Research Ethics Committee of Botucatu Medical School approved to perform the research with verdict No. 607.171. The data collection period was from May 2014 to May 2015, and the total sample was of 106 women. From these patients, 66 underwent breast-conserving surgery and 40 underwent mastectomy, and they were followed up by the mastology team of the Gynecology Outpatient Service of Botucatu University Hospital. Among the main results, it was verified that, in the functional scale of the EORTC questionnaires, the patients who underwent breast-conserving surgery had averages higher than those of the mastectomy group in most domains. However... (Complete abstract click electronic access below)
Mestre
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5

Opara, Esther. "Predictors of Mastectomy in Male Breast Cancer." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3956.

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Male breast cancer (MBC) is rare, and research on the predictors of MBC has been limited because of inadequate funding in and outside of the United States. One goal of this study was to eradicate the stereotyping of breast cancer as a female disease. The emergence of medical technology and education to benefit the public will help to ensure greater health awareness at the individual, community, and global levels. The purpose of this study was to understand the influence of the predictors of age; race (Black, White, and Other); and grade of cancer (I, II, or III) on the outcome of mastectomy in MBC. The study was guided by the social determinants of health model. A quantitative approach was used to analyze archival data from 2011 to 2013 in the Surveillance Epidemiology and End Results (SEER) database using SPSS v.23. Data from 427 MBC patients ages 18 years and older from the United States comprised the sample. The SEER data were analyzed using logistic regression analysis. Results showed that of the 427 cases of MBC that were analyzed, 55 had a diagnosis of Grade I, 190 had a diagnosis of Grade II, and 182 had a diagnosis of Grade III. For 3 years, 116 men had undergone mastectomy. Grade I cancer, Grade II cancer, and Grade III cancer were statistically insignificant predictors of mastectomy; however, age, race was a statistically significant predictor of mastectomy among White men with MBC. The results will contribute to social change initiatives by educating the public about the predictors of mastectomy in MBC patients. The results also will increase the current knowledge base by informing the public, clinical professionals, and patients about the relationship of the predictors of age; race; and grade of cancer (I, II, or III) on the outcome of mastectomy in MBC.
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Gonçalves, Maria Lúcia dos Ramos. "Comparação entre dois protocolos analgésicos em cadelas submetidas a mastectomia." Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2011. http://hdl.handle.net/10400.5/3751.

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Dissertação de Mestrado Integrado em Medicina Veterinária
A maior importância dada ao tratamento analgésico na medicina veterinária nos últimos anos tem aumentado o interesse e preocupações sobre a eficácia, os efeitos adversos sistémicos, custo e o uso abusivo dos diferentes agentes analgésico. O presente estudo teve como objectivo comparar dois protocolos analgésicos em cadelas submetidas a mastectomia unilateral (n=20). As variáveis em estudo para a avaliação do grau de dor foram os valores da escala de dor da universidade de Melbourne (EDUM) em T0 (pré-cirúrgico), T1 (1ª h pós-cx), T2 (2ªh pós-cx), T3 (3ª h pós-cx), T4(4ªh pós-cx) e T48 (48ªh pós-cx) e o doseamento de cortisol sérico em T0 e T1. No grupo controlo (grupo B) os animais (n=11) foram pré-medicados com buprenorfina IM (0,015mg/kg) e no grupo estudo (grupo BL) os animais (n=9) foram também submetidos a pré-medicação com buprenorfina IM (0,015mg/kg), sendo realizada no pós-operatório analgesia local através da infiltração de lidocaína (4mg/kg) na zona da sutura. A análise estatística do presente estudo foi realizada com o programa estatístico informático Graph Pad InStat utilizando o teste t Welch's, análise de variância “One way ANOVA”, teste de comparações múltiplas de Tukey-Kramer e o coeficiente de correlação Pearson (r). Os resultados são apresentados como média ± desvio-padrão. No grupo B a média na pontuação obtida pela EDUM foi de 3,73±1,35 em T0; de 7,91±4,64 em T1; em T2 foi de 7,55±4,27; 8,09 ± 3,91 em T3; 7,91±3,59 em T4 e finalmente em T48 foi de 5,22 ± 2,49. No grupo BL em T0 a média foi de 4 ± 1,22; de 6,22 ± 1,92 em T1; em T2 a pontuação média foi de 6,22±2,33; em T3 registou-se um valor médio de 5,78±2,11; 6,33±2,12 em T4 e finalmente em T48 foi de 4 ± 1,22. Apesar do valor médio do grupo BL em todos os períodos de observação, excepto no T48, ser menor do que no grupo B, não se observaram diferenças estatisticamente significativas entre os dois grupos (teste t Welch‟s ; p>0,05 ). No grupo B o cortisol sérico aumentou significativamente de T0 (4.36±2.03) para T1 (7.36±3.42; teste t para dados emparelhados, p= 0.0055), enquanto que no grupo BL o cortisol de T0 (6.84±6.4) para T1 (5.3±3.81) diminuiu, não sendo esta diminuição significativa (teste t para dados emparelhados, p= 0.4552). De acordo com os resultados do doseamento do cortisol, a infiltração local de lidocaína na zona da sutura no pós-operatório imediato, é significativamente benéfica em cadelas submetidas a mastectomia. Porém, recorrendo a avaliação da dor pela EDUM esse benefício não é evidente.
ABSTRACT - The increased importance given to analgesic treatment in veterinary medicine recently, has triggered more interest and concerns about effectiveness, adverse systemic effects, cost and abusive use of the different analgesic agents. This study aimed to compare two analgesic protocols in dogs undergoing unilateral mastectomy (n=20). The variables in the study to assess the degree of pain were the values of the pain scale from the University of Melbourne (EDUM) at T0 (preoperative), T1 (1hour post-cx), T2 (2h post-cx), T3 (3h post-cx), T4 (4h post-cx) and T48 (48h post-cx) and the measurement of serum cortisol levels at T0 and T1. In control group (B) the animals (n=11) were pre-medicated with buprenorphine IM (0,015mg/kg). In the study group (BL) the animals (n=9) were also pre-medicated with buprenorphine IM (0,015mg/kg), however, during the post-operative period, this group was submitted to local infiltration of lidocaine (4mg/kg) in the suture area. Statistical analysis of the present study was performed with statistical program Graph Pad InStat using Welch's t test, analysis of variance "One way ANOVA", test for multiple comparisons Tukey-Kramer and Pearson(r)‟s correlation coefficients. The results are presented as mean ± standard deviation. In B group the mean score obtained by EDUM was 3.73±1.35 at T0, 7.91±4.64 at T1, T2 was 7.55±4.27, 8.09±3.91 at T3, 7.91±3.59 at T4 and finally T48 was 5.22±2.49. In BL group at T0 the mean was 4±1.22, from 6.22±1.92 at T1, at T2 the mean score was 6.22±2.33, at T3 there was an mean of 5.78±2.11, 6.33±2.12 at T4 and finally T48 was 4±1.22. Although the mean value in the BL group at all periods of observation, except for T48, was lower than In the B group, there were no statistically significant differences between the two groups (Welch's t test, p> 0.05). In B group serum cortisol increased significantly from T0 (4.36±2.03) to T1 (7.86±3.42; t test for paired data, p = 0.0055), while in the BL group cortisol from T0 (6.84±6.4) to T1 (5.3±3.81) decreased but not significantly (t test for paired data, p = 0.4552). According to the results of the serum cortisol levels, the local infiltration of lidocaine in the suture area in bitches undergoing mastectomy, in the immediate postoperative period, is significantly beneficial. However, using pain assessment by EDUM this benefit is not evident.
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Wright, Lauren. "Women's experience of decision-making regarding prophylactic mastectomy." Thesis, University of Leicester, 2017. http://hdl.handle.net/2381/40400.

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Literature review: A systematic review of the existing literature was conducted, eliciting ten studies which met the inclusion criteria examining psychosocial predictors of prophylactic mastectomy in women with a confirmed BRCA gene alteration. Narrative synthesis identified that results coalesced around temporal, familial and other factors including conceptualisation of cancer and perceived risk. The relative scarcity of published research, and an accompanying dominant biomedical focus, highlight that further exploration of psychosocially predictive factors, particularly those which are modifiable, is needed. Research report: Interpretative Phenomenological Analysis (IPA) was utilised to explore five women’s experience and sense-making of their decision to opt for prophylactic mastectomy, and how they experienced the period between opting for preventative surgery and waiting for this to occur. Four superordinate themes were identified: ‘It’s a no-brainer’ illuminated how women approached and made sense of their decision; ‘good breast/bad breast’ reflected women’s experience of simultaneously holding conflicting views towards their breasts; ‘big B on my shoulder’ highlighted worry held in relation to geneticised identity; and ‘the preciousness of life’ illustrated the impact of familial and existential experience. Findings emphasised the importance of clinicians remaining mindful to experiential, emotional and systemic motivations for surgery and to recognise and support women with the potential tension they may still hold as they debate and navigate prophylactic mastectomy. Critical appraisal: A reflective account is presented to support the consolidation of personal and professional learning points and reflections made during the research process.
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Flannagan, Caroline M. "Decision support intervention for reconstructive surgery following mastectomy." Thesis, Ulster University, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697542.

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Background Post mastectomy breast reconstruction is an elective procedure offered to women as part of surgical treatment for breast cancer. Choosing to have a reconstruction, or not, and when, is a timely and challenging decision for women in an emotive environment. Decision support interventions (DSIs) have proved beneficial in enabling decision making with patients and clinicians in similar situations of clinical equipoise. The goal of the DSI is to facilitate a decision that is reflective of the patient's own priorities and preferences. However, the implementation of DSIs into routine clinical practice has proved challenging. The thesis reports on the development of a post mastectomy breast reconstruction DSI and on the feasibility of implementing a DSI in the clinical environment. Methods Women's decision making about breast reconstruction was examined through a literature review and a thematic analysis of interviews with breast cancer survivors. A collaborative development framework and iterative process were utilised to design the breast reconstruction DSI. The breast reconstruction DSI was introduced into the clinical environment in a feasibility study to identify potential barriers and facilitators to implementation. A case study approach, including the decisional conflict scale and qualitative methods, examined the perceptions and experience of the patients and clinicians using the DSI in a breast cancer clinic. Results The Option Grid DSI was published on-line as part of the Option Grid Collaborative. In feasibility testing, its flexibility and accessibility were positive features in terms of its implementation. The content and format facilitated the comparison of options. The timing of when it was introduced impacted its effect on patient decision making. Conclusions The support of local stakeholders was significant in the development of the DSI. The Option Grid DSI can be integrated into routine clinical practice, and gave some consultations more structure. Patient participants in the feasibility study found it constructive in facilitating their decision making. Further testing to explore the timing of the DSI and its impact on a wider audience is warranted.
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Romana, Ana Marta Lourinho. "Estudo preliminar da variação dos níveis de cortisol em doentes da espécie Canis familiaris sujeitos a mastectomia por doença oncológica da mama." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2016. http://hdl.handle.net/10400.5/11557.

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Dissertação de Mestrado Integrado em Medicina Veterinária
A esperança média de vida dos animais domésticos tem sido uma variável crescente à qual se junta um aumento do aparecimento de doenças associadas à geriatria, nas quais se destaca a doença oncológica da mama. Em Medicina Humana são já diversos os estudos que relacionam a concentração de cortisol com o comportamento dos tumores mamários. O presente estudo foi realizado numa amostra de 15 indivíduos da espécie Canis familiaris (N=15), do género feminino, com diagnóstico de tumor de mama, e sujeitos a mastectomia total unilateral. Teve como objetivos: 1) caracterizar a variação das concentrações de cortisol num período pré- e pós-cirúrgico; 2) estudar a relação entre as concentrações de cortisol e a sua variação com os parâmetros: idade, peso vivo, localização das massas tumorais, número de mamas envolvidas na doença oncológica, estadiamento clínico da doença, presença de doenças de base, e estado teriogenológico da fêmea; e ainda 3) estudar a relação entre a idade e o peso vivo das doentes com os parâmetros: localização das massas tumorais, número de mamas envolvidas na doença oncológica e estadiamento clínico da doença. Cada doente foi sujeita a uma colheita biológica de sangue periférico para quantificação dos níveis de cortisol, em 2 tempos diferentes T0 (imediatamente pré-cirurgia) e T1 (10 dias após a cirurgia). Os resultados obtidos revelaram que existiu uma diminuição na média de valores de cortisol de T0 para T1, o que pode ser explicado pela remoção da massa tumoral, e que de todos os parâmetros estudados apenas o peso tem uma relação estatisticamente significativa com os níveis de cortisol, provavelmente devido ao efeito direto dos glucocorticoides no tecido adiposo.
ABSTRACT - PRELIMINARY STUDY OF CORTISOL LEVEL VARIATIONS IN CANIS FAMILIARIS PATIENTS SUBMITTED TO MASTECTOMY DUE TO MAMMARY TUMOUR DISEASE - The lifespan of domestic animals has been an increasing variable. Along with that, geriatric diseases have raised, from which breast cancer is highlighted. In Human Medicine, several studies correlate the cortisol level with the behavior of breast tumors. The present study used a sample of 15 bitches (N=15), previously diagnosed with breast tumor and submitted to a unilateral total mastectomy, and aimed 1) to characterize the cortisol levels variation between the pre and post surgical period; 2) to study the relationship between cortisol levels variation with parameters such as age, body weight, mammary location of the tumors, the location of the affected mammary gland, the clinical stage of the disease, the presence of underlying diseases and the bitch theriogenological state; and 3) to investigate the relationship between the age and body weight of patients and the parameters mammary location of the tumors, the location of the affected mammary gland, the clinical stage of the disease. A sample of peripheral blood was collected from each patient in order to quantify the cortisol levels in two different time points T0 (immediately before surgery) and T1 (10 days after surgery). The obtained results revealed that cortisol levels decrease from T0 to T1, which can be explained by the tumor excision. From all the studied parameters, only the body weight showed statistically significant differences with the cortisol levels, probably due to a direct effect of glucocorticoids on the fat tissue.
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10

Kim, Janet Heejung. "Cyclooxygenase-2 Expression in Post-Mastectomy Chest Wall Relapse." Yale University, 2006. http://ymtdl.med.yale.edu/theses/available/etd-06282006-104942/.

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The purpose of this study was to assess the prognostic significance and clinical correlations of cyclooxgenase-2 expression (COX) in a cohort of patients treated with radiation (RT) for post-mastectomy chest wall relapse (PMCWR). Between 1975 and 1999, 113 patients were treated for isolated PMCWR. All patients were treated with biopsy and/or excision of the CWR followed by RT. Median follow-up was 10 years. All clinical data including demographics, pathology, staging, receptor status, HER-2/neu status, and adjuvant therapy were entered into a computerized database. Paraffin-embedded CWR specimens were retrieved from 42 patients, of which 38 were evaluated, created into a tissue microarray, stained by immunohistochemical methods for COX, and graded 0-3+. A score of 2-3+ was considered positive. Overall survival from original diagnosis for the entire cohort was 44% at 10 years. Survival rate after chest wall recurrence was 28% at 10 years. The distant metastasis-free survival rate after CWR was 40% at 10 years. Local-regional control of disease was achieved in 79% at 10 years after CWR. COX was considered positive in 13 of 38 cases. COX was inversely correlated with ER (p= .045) and PR (p = .028), and positively correlated with HER-2/neu (p =.003). COX was also associated with a shorter time to PMCWR. The distant metastasis-free rate for COX negative patients was 70% at 10 years, compared with 31% at 10 years for COX-2 positive patients (p = 0.029). COX positive had a poorer local-regional progression-free rate of 19% at 10 years, compared with 81% at 10 years for COX negative (p = 0.003). Outcome following RT for PMCWR is relatively poor. Positive COX correlated with other markers of poor outcome including a shorter time to local relapse, negative ER/PR and positive Her-2/neu status. Positive COX correlated with higher distant metastasis and lower local-regional control of disease. If confirmed with larger studies, these data have implications with respect to the concurrent use of COX-2 inhibitors and radiation for PMCWR.
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11

Natha, Fehmida. "The experiences of women undergoing therapeutic and prophylactic mastectomy." Thesis, Lancaster University, 2015. http://eprints.lancs.ac.uk/78170/.

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It is well established mastectomy affects a woman’s sexual functioning. However, there is growing recognition that the intrapsychic effects of mastectomy, such as changes to one’s body-image and physical integrity can threaten embodied experiences and gendered identity. This is seen to alter how a woman appraises her sense of femininity; influencing her engagement in sexual activity and impacting upon intimate relationships. Accordingly, the aim of this review was to explore and elaborate the impact of mastectomy upon a woman’s sexuality through a synthesis of relevant qualitative literature. A systematic literature search of five databases (Academic Search Complete, CINAHL, PsychARTICLES, PsychINFO, and MEDLINE) was undertaken using terms for mastectomy, sexuality, and qualitative data. A meta-synthesis was conducted on the data from the twelve studies obtained. Three overarching themes were derived highlighting how mastectomy impacts upon a woman’s femininity, sense of personal attractiveness and desirability within intimate relationships, and the importance of an intimate partners support in enabling women to adjust to their altered bodies. Findings have important practice implications. Particularly, the need for clinicians to offer interventions that aim to maintain the relationship between a woman, her altered body, and partner after mastectomy.
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Poon, Yuet-fai Helena. "The psychological reactions of breast cancer patients with mastectomy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B29697475.

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13

Larsson, Linneá. "Immediate breast reconstruction after mastectomy at Örebro University Hospital." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-73266.

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Abstract Introduction Immediate breast reconstruction (IBR) can be offered to breast cancer patients after mastectomy. A satisfactory breast symmetry has positive effects on psychosocial morbidity, quality of life and body image. The frequency of IBR were in 2017 in Region Örebro County 4%, lower than the national target on 20%. Aim The aim is to provide an overview of the work with IBR at Örebro University Hospital in 2016, regarding frequency of IBR, work with IBR at multidisciplinary team conferences, documentation of the patient’s opinion about IBR, delayed reconstructions, patient characteristics and presence of contraindications. Material and methods This was a retrospective study of all women who underwent mastectomy at Örebro University Hospital in 2016. Results Five of the 103 women got IBR with expander implants in connection to mastectomy, additionally 28 had no contraindications for IBR. Five of the women have discussed about IBR at multidisciplinary team conferences and seven had notes about their attitude to IBR. Ten women underwent delayed reconstruction during the follow-up, additional seven patients were waiting for surgery. There were no significant differences in patient characteristics between the groups “mastectomy and IBR” and “mastectomy only”. Conclusions The low frequencies of performed IBR, discussions at multidisciplinary team conferences and documentation of the patient’s opinion about IBR indicate that there is space for a more active work about IBR. Besides the women who got IBR, there were additionally 28 women without any contraindications for IBR, indicating that there is a considerable group that can become candidates for IBR.
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Zhu, Shenglong, and Jiaying Zou. "The experience of women after Mastectomy– A Descriptive Review." Thesis, Högskolan i Gävle, Avdelningen för vårdvetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-36625.

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15

Gahm, Jessica. "Bilateral prophylactic mastectomy and immediate breast reconstruction with implants." Stockholm : Section of Reconstructive Plastic Surgery, Karolinska Institutet, 2009. http://diss.kib.ki.se/2009/978-91-7409-704-7/.

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16

Ringberg, Hagberg Anita. "In situ carcinoma of the breast aspects on natural history and treatment with special reference to subcutaneous mastectomy /." Malmö : Dept. of Plastic and Reconstructive Surgery, Lund University, Malmö General Hospital, 1992. http://books.google.com/books?id=qHVsAAAAMAAJ.

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Sullivan, Megan. "Beautiful can be Bold: A New Way to Wear the Drain." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1460653322.

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Melo, Elizabeth Mesquita. "AvaliaÃÃo de orientaÃÃes sistematizadas de enfermagem no pÃs-operatÃrio de mulheres submetidas à mastectomia." Universidade Federal do CearÃ, 2007. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=683.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior
Enfatiza-se a importÃncia do acompanhamento de enfermagem no pÃs-operatÃrio de mastectomia, visando à identificaÃÃo de problemas na busca da qualidade de vida da mulher e minimizaÃÃo de alteraÃÃes fÃsicas e psicolÃgicas, para sua melhor readaptaÃÃo ao ambiente social. O estudo teve como objetivo geral: avaliar a contribuiÃÃo da assistÃncia de enfermagem desenvolvida no pÃs-operatÃrio, para a readaptaÃÃo fÃsica, emocional e social da mulher mastectomizada e especÃficos: identificar diferenÃas nas respostas fÃsicas, emocionais e sociais entre as mulheres que foram ou nÃo submetidas à orientaÃÃo sistematizada de enfermagem; conhecer as complicaÃÃes pÃs-operatÃrias presentes nos dois grupos de mulheres; e detectar as dÃvidas entre os grupos em relaÃÃo aos cuidados necessÃrios para a prevenÃÃo de complicaÃÃes apÃs a mastectomia. Estudo experimental, do tipo ensaio clÃnico randomizado controlado. Aplicou-se uma intervenÃÃo a um grupo de mulheres (grupo intervenÃÃo), no pÃs-operatÃrio imediato de mastectomia, para a observaÃÃo de seus efeitos, em relaÃÃo a outro grupo em que nÃo foi realizada (grupo controle). Dados coletados entre novembro de 2005 e marÃo de 2006, em uma instituiÃÃo especializada em oncologia, Fortaleza-CearÃ. A populaÃÃo constou de portadoras de doenÃas da mama que realizaram cirurgia nesse perÃodo, sendo composta por 80 mulheres, 40 em cada grupo, selecionadas aleatoriamente. Dados organizados e analisados quantitativamente, submetidos à anÃlise estatÃstica. Utilizou-se o Programa Microsoft Office Excel 2003, para o banco de dados. Considerou-se o nÃvel de significÃncia dos testes igual a 5%. O projeto foi aprovado pelo comità de Ãtica da instituiÃÃo. A faixa etÃria predominante foi 36 a 68 anos (87,5%); 60% procediam do interior do estado; 57,5% eram casadas. A mastectomia radical modificada com esvaziamento axilar foi o procedimento mais realizado (56%) e o diagnÃstico mais comum carcinoma ductal infiltrante (58,8%). Identificou-se diferenÃa estatisticamente significativa quanto à manifestaÃÃo de desamparo, falta de forÃas, sensaÃÃo de cansaÃo e tensÃo, com um Ãndice de alteraÃÃo emocional menor no grupo-intervenÃÃo. 57,5% do grupo intervenÃÃo, apÃs a cirurgia, retomaram atividades que beneficiavam a recuperaÃÃo, observado em 7,5% do grupo controle. Foram manifestadas dÃvidas sobre as atividades por 57,5% das mulheres do grupo controle e 37,5% do grupo intervenÃÃo. Houve mais complicaÃÃes cirÃrgicas no grupo controle (92,5%) em relaÃÃo ao grupo intervenÃÃo (57,5%). Este grupo apresentou menos dificuldades para manusear o dreno de sucÃÃo (7,5%), sendo 31,6% no grupo controle. O acompanhamento direcionado ao grupo intervenÃÃo contribuiu para a adoÃÃo de atitudes positivas relacionadas aos cuidados com o braÃo do lado operado. A orientaÃÃo sistematizada de enfermagem no pÃs-operatÃrio de mastectomia possui valor inestimÃvel, visto que proporciona o esclarecimento de dÃvidas a respeito da doenÃa e da cirurgia, e possibilita a adoÃÃo de cuidados favorÃveis à recuperaÃÃo mais rÃpida da mulher e a sua readaptaÃÃo.
It is emphasized the importance of nursing attendance in the post-operatory of mastectomy aiming the identification of problems for womenâs life quality and minimization of physical and psychological alterations, so that they have a better readaptation to social environment. The study had as its general objective to evaluate the contribution of nursing assistance developed in the post-operatory for physical, emotional and social readaptation of mastectomized women. The specific objectives were: to identify differences in physical, social and emotional responses among women who were submitted or not to nursing systematized orientation; to know the post-operatory complications present in the two groups of women; and to identify in the groups doubts related to necessary care to prevent complications after the mastectomy. It is an experimental study, a randomized controlled clinical essay. An intervention was applied in a group of women (group intervention) in the immediate post-operatory of mastectomy to observe its effects, in relation to the other group in which the intervention was not carried out (group control). The data was collected between November, 2005 and March, 2006 in an institution which is specialized in oncology, Fortaleza-CearÃ. The population was composed of holders of breast diseases who were submitted to surgeries during this period, and was composed of 80 women, 40 in each group, selected at random. The data was organized and analyzed quantitatively and submitted to statistical analysis. The Program Microsoft Office Excel 2003 was used for the data bank. The significance level of the tests was considered equal to 5%. The Project was approved by the ethical committee of the institution. The predominant age group was 36 to 68 years old (87,5%); 60% came from the state countryside. 57,5% were married. The modified radical mastectomy with axillary dissection was the most common procedure (56%) and the most common diagnosis was infiltrating ductal carcinoma (58,8%). It was identified significative statistical difference concerning manifestation of abandonment, lack of vigor, feeling of tiredness and tension, with an indicator of emotional alteration lower in the group intervention. 57,5% of the group intervention, after the surgery, restarted activities which helped in the recuperation, what was observed in only 7,5% of the group control. Doubts about the activities were manifested by 57,5% of women from the group control and 37,5% from the group intervention. There were more surgery complications in the group control (92,5%) in relation to the group intervention (57,5%). This group presented less difficulty to use the suction drain (7,5%), being 31,6% in the group control. The attendance directed to the group intervention contributed to the adoption of positive attitudes towards the care with the arm from the operated side. The nursing systematized orientation in the post-operatory of mastectomy has inestimable value, considering it provides elucidation of doubts about the disease and the surgery, and makes possible the adoption of care which is favorable to womenâs faster recuperation and to their readaptation.
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Le, Vesconte Helen. "Body image and body image investment in mastectomy and breast reconstruction." Thesis, University of Southampton, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617817.

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Breast cancer is the most common cancer in women in the UK and both diagnosis and treatment can cause significant levels of distress and impaired quality of life. There arc many factors that relate to psychological distress in women coping with breast cancer including changes in body image. Appearance-related side effects, such as hair loss, are often reported as more severe than side-effects such as nausea and fatigue. A review of the literature explores the links between mainstream body image models and breast cancer. The impact of mastectomy on body image and mental health outcomes is discussed as well as the role of breast reconstruction, as this may help to alleviate women's body image difficulties and emotional distress following surgery. The need to understand the role of body image investment within theoretical models as well as for breast cancer patients facing mastectomy and immediate reconstruction is highlighted, especially in light of the inconsistencies found within the literature. The empirical paper investigates the psychosocial and body image outcomes of two groups of women: those undergoing mastectomy alone and those undergoing mastectomy with immediate breast reconstruction. It also examines whether investment in body image acts as a moderating variable between surgery type and subsequent psychological distress. Both groups reported deteriorations in their body image following surgery, though this did not always correspond with increased emotional distress. Women who reported a higher body image investment who underwent mastectomy alone had the poorest outcomes.
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Lloyd, Susannah. "Understanding the experience of prophylactic bilateral mastectomy : a grounded theory study." Thesis, University of East Anglia, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302194.

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21

Shatley, Joseph Andrew, and L. Lee Glenn. "Sexuality and Quality of Life of Breast Cancer Patients Post Mastectomy." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/7510.

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Excerpt: Manganiello et al., (2010) aimed to evaluate the sexual functioning of mastectomy patients and its association with their quality of life. There are two shortcomings with this study that render its conclusions invalid, or at least, weakly supported.
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22

Hunt, Senetta Jean. "Factors Influencing African American Women to Undergo/Forego Reconstruction after Mastectomy." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4703.

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The factors associated with the decision of African American women to undergo/forego breast reconstruction after mastectomy has not been well researched. The purpose of this quantitative, correlational study was to determine the extent to which certain factors (age, religion, confidence level, and education) were associated with the decision to forgo or undergo breast reconstruction after mastectomy among African American women. Using the social-cognitive theory as the framework, the study focused on the decision-making process regarding breast reconstruction after mastectomy among African American women in Florida. The research questions for this study were to determine to what extent age, religion, confidence level, and education are associated with the decision of African American women to forego or undergo breast reconstruction after mastectomy. Data were collected using the Decision Self-efficacy and Religious Coping Activities scales from 88 African American women living in North Central Florida who had a mastectomy. Data were analyzed using Chi-square test and logistic regression. The results showed a significant a significant a significant a significant a significant a significant a significant a significant a significant a significant a significant a significant a significant a significant relationship (relationship (relationship (relationship (relationship (relationship (relationship (relationship (relationship (relationship (relationship (relationship (relationship (relationship (p = .042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the.042) between the confidence level of decision-making and the decision to forego or undergo breast reconstruction after mastectomy. It was important to examine the extent to which certain factors contributed to decision-making about breast reconstruction after mastectomy in African American women as this can provide an opportunity to cultivate positive social change by being able to tailor support services for African American women after mastectomy based on the role various factors may play.
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Covich, Jennifer Lin. "The relationship between breast reconstruction and psychological adjustment when a mastectomy is necessary /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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LINDOSO, Sue Kaneko. "Tumores da mama em cadelas : estudo dos níveis séricos de estradiol E-2 e progesterona associados à histopatologia." Universidade Federal Rural de Pernambuco, 2012. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5867.

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The mammary neoplasms comprises aproximatel 50% ofthe diagnosed tumors in the bitch. Although female sexual honnones play a fundamental role in the development of these tumors in mammals, the value of the suppression hormonal (ovariohysterectomy) as an adjuvam treatment remains controversial. The objective ofthis review is to discuss some aspects related to the hormonal influence in the pathogenesis of the canine tumor, as well as the therapeutic value ofspaying. when accomplished in the moment ofthe mastectomy.
Os tumores da mama constituem aproximadamente 50% dos tumores diagnosticados em cadelas. Apesar dos hormônios sexuais femininos desempenharem papel fundamental no desenvolvimento desses tumores em mamíferos, o valor da supressão hormonal pela ovário-histerectomia como auxiliar no tratamento do tumor de mama em caninos permanece controverso. O objetivo desta pesquisa é discutir alguns aspectos relacionados à influência hormonal na etiologia de tumores mamárias em cadelas, assim como o valor terapêutico da castração, quando realizada no momento da mastectomia.
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周永昌 and Wing-cheong Louis Chow. "Modulation of acute inflammatory response caused by surgical trauma ina mastectomy model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31979622.

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26

Wilson, Katherine. "Factors Considered by BRCA1/2 Carriers Regarding Timing of Risk-Reducing Mastectomy." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1623165972480045.

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27

Benediktsson, Kristinn P. "Nipple-sparing subcutaneous mastectomy and immediate reconstruction with implants in breast cancer /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-199-9/.

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Greener, Judith Robin. "Contralateral Prophylactic Mastectomy: An Exploratory Approach to Understanding the Decision Making Process." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/354121.

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Public Health
Ph.D.
The rate at which women choose mastectomy has grown dramatically, and of particular note is the increase in contralateral prophylactic mastectomy (CPM). For women with no history of breast cancer or genetic risk, CPM represents a treatment decision that does not offer better long-term outcomes than the decision not to remove a healthy breast and may be associated with increased surgical risk and interventions, increased cost to the healthcare system, and potential adverse psycho-social outcomes. To better understand the decision making process regarding the election of CPM among women with early stage unilateral breast cancer, with no family history or genetic risk, a three-phase exploratory study was conducted. Qualitative in-depth interviews were conducted with healthcare providers who have close interaction with women during the decision making process (N=3) and patients who made a surgical decision about breast cancer treatment within the past three years (N=11). These two phases informed the design of the quantitative internet survey, conducted among women diagnosed with early stage breast cancer in the process of making a surgical decision (N=336). The survey design was also guided by an existing model for treatment decision making which uses a social ecological framework (Revenson & Pranikoff, 2005). In addition to descriptive analyses, perceptual mapping was utilized to understand patients’ conceptualizations of the relative importance of factors considered during the decision making process, and AdSAM® was used to gauge emotional response. Results suggest that women more likely to elect CPM demonstrate an emotional response to a generalized fear of cancer, along with the need to take control of their situation. In addition, retrospective interviews emphasized somewhat different reasons for electing CPM, highlighting the importance of prospective research in studying the decision making process.
Temple University--Theses
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Chow, Wing-cheong Louis. "Modulation of acute inflammatory response caused by surgical trauma in a mastectomy model." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23636464.

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Serafim, Roseane Christhina da Nova Sa. "Corpo mastectomizado e representações: rede de significações que conduzem a ação." Universidade Federal da Paraí­ba, 2013. http://tede.biblioteca.ufpb.br:8080/handle/tede/6961.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
The present thesis aimed to identify the social representations of the mastectomized body made by women who have undergone a mastectomy due to breast cancer. Based on the theory of social representations, it has been established that removal of breast, which is an organ that is ingrained in sociocultural symbolism, calls the social actors to reissue the figure of the female body. After approval of the Ethics Committee in Research, an exploratory and descriptive study has been started. In this study, 23 women between 30 and 59 years-old (M= 49, SD= 5.8) have been chosen for convenience, intentionally and non-probabilistically. The instruments used for data collection were the Bio-sociodemographic Questionnaire, the Drawing-story with Theme and Semistructured Interview. The data analysis and treatment followed the specificity of the questionnaire and of each technique, so it was consequently used the SPSS for descriptive analysis, the thematic content analysis and the Alceste for lexical analysis. Thus, it is stated that among the participants the results indicate an average of six years of mastectomy (SD= 3.7). Regarding the use of breast implant 14 women said they use mobile prosthesis made of silicone or birdseed. And, concerning the satisfaction with body image, 13 participants said they were satisfied. The verbal-graphic material seized by Drawing-story with Theme, after passing through the critical analysis of three judges, was grouped into three emprirical categories (stigmatization, social adjustment strategies and support network) and 12 symbolic subcategories. The Descending Hierarchical Classification of the data processed by Alceste was organized in two subcorpora represented by thematic axes. The thematic axis of support network and functional limitations brought together the thematic classes 1 (spirituality as protection support) and 3 (functional limitations). Yet thematic stigma and social adjustment coalesced thematic classes 2 (negative representation of the body in post mastectomy) and 4 (a breast implant as a rectification element). Based on the analysis of the results, it is inferred that social representations objectified from the graphisms and narratives reveal the mastectomized body as an inseparable symbolic correspondent from the representation subject, from the representational object and existential experience generated by the discovery of the lump which confirms the breast cancer diagnosis and by the consequences arising not only from the mastectomy, but from the treatment that also involves chemotherapy and radiotherapy. Emerging as an icon of social stigma, the mastectomized body also objectifies from the intersubjective experience of faith associated with altruistic practices, and from the use of external breast prostheses and reconstructive plastic surgery. In the speech of the participants, the use of mobile prosthesis and breast reconstructive surgery configure as possibilities for social adjustment and rectification of group belonging and body image. As developments, this thesis suggests that studies with larger numbers of participants considering the gender difference, and the development of more effective therapeutic actions with regard to the rescue of autonomy, leadership and self-esteem of women who need to undergo mastectomy as a result of breast cancer. Finally, we aim to broaden the dialogues between the field of oncology and psychology.
Esta tese objetivou apreender as representações sociais do corpo mastectomizado elaboradas por mulheres que se submeteram à mastectomia em decorrência do câncer de mama. Com base na Teoria das representações sociais preconizou que retirada da mama, um órgão impregnado de simbolismo sociocultural, convoca os atores sociais a reeditarem a figura do corpo feminino. Após a aprovação do Comitê de Ética em Pesquisa, procedeu-se com um estudo descritivo e exploratório. Neste estudo, 23 mulheres entre 30 e 59 anos (M= 49 anos; DP= 5,8) foram escolhidas por conveniência, de forma intencional e não probabilística. Os instrumentos utilizados para a coleta dos dados foram o Questionário Biosociodemográfico, a Técnica do Desenho-estória com Tema e a Técnica da Entrevista Semiestruturada. A análise dos dados seguiu a especificidade do questionário e de cada técnica, por isso utilizou-se o SPSS para análise descritiva, a análise de conteúdo temática e o Alceste para análise lexical. Após a descrição dos resultados, observou-se que as participantes apresentaram uma média de seis anos de mastectomia (DP= 3,7). Quanto ao uso de prótese mamária 14 disseram que usam a prótese móvel feita de alpiste ou silicone. E com relação à satisfação com a imagem corporal 13 participantes disseram estar satisfeitas. O material gráfico-verbal apreendido através do Desenho-estória com Tema Depois após passar pela análise criteriosa de três juízes foi agrupado em três categorias empíricas (estigmatização, estratégias de ajustamento social e rede de suporte) e 12 subcategorias simbólicas. A Classificação Hierárquica Descendente dos dados processados pelo Alceste foi organizada em dois subcorpora representados por eixos temáticos. O eixo temático rede de suporte e limitações funcionais aglutinou as classes temáticas 1 (espiritualidade como suporte de proteção) e 3 (limitações funcionais). Já o eixo temático estigma e ajustamento social aglutinou as classes temáticas 2 (representação negativa do corpo no pós mastectomia) e 4 (prótese como elemento de retificação). Com base na análise dos resultados infere-se que as representações sociais objetivadas a partir dos grafismos e narrativas desvelam o corpo mastectomizado como um correspondente simbólico indissociável do sujeito da representação, do objeto representacional e da experiência existencial gerada pela descoberta do nódulo que ratifica o diagnóstico do câncer de mama e pelas sequelas oriundas não só da mastectomia, mas do tratamento que envolve também a quimioterapia e a radioterapia. O corpo mastectomizado ao emergir como ícone de estigma social objetiva-se, também, a partir da experiência intersubjetiva da fé associada a práticas altruístas, e do uso externo da prótese mamária e da cirurgia plástica reparadora. Na fala das participantes o uso da prótese móvel e a realização da cirurgia reconstrutora da(s) mama(s) configuraram-se como possibilidades de ajustamento social e retificação da pertença grupal e da imagem corporal. Como desdobramentos, esta tese sugere que sejam realizados estudos com maior número de participantes considerando a diferença de gênero, e a elaboração de ações terapêuticas mais eficazes no que concerne ao resgate da autonomia, protagonismo e autoestima das mulheres que precisam se submeter à mastectomia em decorrência do câncer de mama. Por último, almeja-se ampliar os diálogos entre o campo da oncologia e da psicologia.
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31

Alvarez, Arroyo Celeste Rocío. "Estrategias de afrontamiento y calidad de vida en mujeres mastectomizadas." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626459.

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El objetivo de la investigación fue explorar la relación entre calidad de vida y estrategias de afrontamiento en 130 mujeres, entre 30 y 86 años, con diagnóstico de cáncer de mama y tratamiento quirúrgico de mastectomía radical modificada. Los instrumentos psicológicos empleados fueron: Brief COPE para medir las estrategias de afrontamiento y EORTC QLQ-C30 para calidad de vida. Los resultados principales demostraron que existen relaciones significativas entre algunas de las dimensiones de calidad de vida con ciertas estrategias de afrontamiento y que su influencia es positiva para la calidad de vida y salud, en términos globales. Lamentablemente no se encontraron diferencias importantes entre estas dimensiones de calidad de vida y estrategia de afrontamiento según el tratamiento recibido (mastectomía radical modificada o MRM con un tratamiento adicional) ni la edad; sin embargo, existen antecedentes científicos que lo presentarían como una opción interesante en una muestra más amplia.  En conclusión, la hipótesis planteada ha sido comprobada parcialmente, ya que sólo algunas estrategias de afrontamiento se llegan a correlacionar con ciertas dimensiones de calidad de vida significativamente.
The objective of the research was to explore the relationship between quality of life and coping strategies in 130 women, between 30 and 86 years, with a diagnosis of breast cancer and surgical treatment of modified radical mastectomy. The psychological instruments used were: Brief COPE to measure coping strategies and EORTC QLQ-C30 for quality of life. The main results showed that there are significant relationships between some of the dimensions of quality of life with certain coping strategies and their influence is positive, in global terms, for the quality of life and health. Unfortunately, there were not important differences between these dimensions of quality of life and coping strategy according to the treatment received (modified radical mastectomy or MRM with additional treatment) or age; however, there is a scientific background that would present it as an interesting option in a larger sample. In conclusion, the hypothesis raised has been partially verified, since only some coping strategies can be correlated with certain dimensions of quality of life significantly.
Tesis
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32

Braude, Lucy. "Understanding and assessing patient suitability for risk-reducing and contralateral prophylactic mastectomy: The development of an assessment template for psychologists." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/17712.

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Background: Women are increasingly opting to undergo mastectomies to decrease risk of developing breast cancer, known as a risk-reducing mastectomy (RRM) or a contralateral prophylactic mastectomy (CPM) when a patient has a cancer diagnosis in one breast. These are sought by a diverse population with varying motivations and suitability for surgery. Patients are often referred to a psychologist for a pre-surgical consultation; however, there is a dearth of literature to guide the content of a pre-surgical consultation. This thesis aimed to develop a psychological assessment template for women considering RRM and CPM. Method: A systematic review was conducted describing the prevalence of, and reasons for, patient satisfaction and regret following RRM (Chapter 2). This provided an understanding of the main issues to address prior to surgery. Qualitative interviews and a focus group explored the role of a psychologist in this context (Chapter 3). Findings from this were used to create a Delphi consensus survey, which was conducted to determine the content of the assessment template. The template was iteratively developed with feedback from clinical psychologists (Chapter 4). Results: The systematic review (Chapter 2) revealed high patient satisfaction with RRM, although some dissatisfaction/regret was noted. The qualitative study (Chapter 3) highlighted the importance of patient understanding, expectations, mental health and decision-making. The Delphi study (Chapter 4) provided consensus on the issues to include in assessment, informing the development of the template. Conclusion: This thesis has culminated in the development of a draft template to guide psychologist assessment of women considering RRM or CPM, to effectively assess patient suitability for surgery, support patients, and preempt challenges within a standardized framework. Future research should refine and trial this tool to ensure that it is feasible and effective.
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33

Elele, Tugba. "A Decision Analytic Model For Early Stage Breast Cancer Patients: Lumpectomy Vs Mastectomy." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607770/index.pdf.

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The purpose of this study was to develop a decision model for early-stage breast cancer patients. This model provides an opportunity for comparing two main treatment options, mastectomy and lumpectomy, with respect to quality of life by making use of Decision Theoretic Techniques. A Markov chain was constructed to project the clinical history of breast carcinoma following surgery. Then, health states used in the model were characterized by transition probabilities and utilities for quality of life. A Multi Attribute Utility Model was developed for outcome evaluation. This study was performed on the sample population of female university students, and utilities were elicited from these healthy volunteers. The results yielded by Multi Attribute Utility Model were validated by using Von Neumann-Morgenstern Standard Gamble technique. Finally, Monte Carlo Simulation was utilized in Treeage-Pro 2006 Suit software program in order to solve model and calculate expected utility value generated by each treatment option. The results showed that lumpectomy is more favorable for people who participated in this study. Sensitivity analysis on transition probabilities to local recurrence and salvaged states was performed and two threshold values were observed. Additionally, sensitivity analysis on utilities showed that the model was more sensitive to no evidence of disease state
however, was not sensitive to utilities of local recurrence and salvaged states.
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34

Bergström, Madeleine. "Skin dose measurement during radiation therapy of mastectomy patients using GafChromicTM EBT3 films." Thesis, Linköpings universitet, Institutionen för medicinsk teknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-144289.

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Purpose: The aim of this study was to develop a method of measuring changes in the skin microcirculation and skin dose for mastectomy patients in connection with the radiation treatment. The distribution of the skin dose, its dependence on the energy of the beam, field geometry and bolus material and the accuracy of the given skin dose in the treatment planning system were studied. Finally, the correlation between the given dose and the changes in skin microcirculation was evaluated. Methods: Skin dose was measured using GafChromic EBT3 films. To evaluate the impact of different energies and field geometry measurements on a PMMA phantom were done. Dose measurements were done using an anthropomorphic phantom and in patients. The measured skin doses were compered to the doses calculated using the treatment planning system. Before and after treatment, skin blood perfusion was measured using laser speckle contrast imaging. In connection with the last measurement also methyl nicotinate was used to increase the perfusion for the measurement. Results: The measurements on the PMMA-phantom indicate that a larger photon energy results in a lower dose to the skin, but a higher exit dose. Furthermore a more oblique angle results in a higher skin dose and a larger field size also results in an increased skin dose. The patient measurements showed that the skin dose was significantly different in different areas of the irradiated field. The highest dose was measured in the area in which a bolus was applied. All patients showed a significant increase in skin blood of the perfusion within the irradiated area. The comparison between the measured doses and the doses calculated using the treatment planning system shows an underestimation of the skin dose by the treatment planning system depending on the incident angle and the presence of bolus material. Conclusion: The distribution of the skin dose during breast cancer radiotherapy in mastectomy patients is heterogeneous with the highest dose in the area of the mastectomy scar, due to the presence of bolus material. A correlation can be noticed between the changed in microcirculation and the radiation dose to the skin. Estimation of the skin dose using the treatment planning system is inaccurate, but film doseimetry offers an easy-to use method to accurately measure the dose to different areas of the irradiated skin.
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35

Reid, Nicola. "Women's experience of coping with body image change following mastectomy : a Q methodology." Thesis, University of Sheffield, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527250.

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36

Emmer, Kathryn. "Mammary Tumor and Mastectomy Synergistically Promote Neuroinflammation in a Breast Cancer Survivor Model." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu155541980882918.

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37

Favolye, Olena, and Nibras Naser. "Bröstcancer hos kvinnor i fertil ålder : Upplevelser efter mastektomi." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-11817.

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Bakgrund: Bröstcancer är den vanligaste cancerformen hos kvinnor. Vid omfattande tumörväxt utförs mastektomi. Hela bröstet inklusive all lymfkörtelvävnad i axillen tas bort. Att få beskedet om att bröstet skall tas bort är en chock och upplevs av många som en livskris. Brösten är en central del i både det fysiska och det psykiska jaget hos de flesta kvinnor. Syfte: Att beskriva upplevelse hos kvinnor i fertil ålder som har genomgått mastektomi. Metod: En kvalitativ litteraturstudie baserad på elva artiklar med kvalitativ ansats. Resultat: I resultatet framkom fem teman: Inverkan på kroppsuppfattning, förändringar i sexuella livet, inverkan på psykiska tillstånd, behov av stöd för att bidra till bra livskvalitet och positiva upplevelser efter cancerbehandlingar. Kvinnor som genomgått mastektomi upplevde negativa förändringar i sin kroppsuppfattning som påverkade flera aspekter i livet såsom sexualitet, partnerskap, föräldraskap och relationer i arbetslivet. Kliniska implikationer: Sjuksköterskans lyhördhet till kvinnor och förståelse av deras kroppsliga och psykosociala förändringar är förutsättningarna för att lindra kvinnornas lidande och främja välbefinnande trots bröstcancersjukdomen och mastektomin.
Background: Breast cancer is the most common cancer among women. At extensive tumor growth a mastectomy is performed. The entire breast including all the lymph node tissue in in the armpit is removed. Getting the news that the breast has to be removed is a shock and is perceived by many as a life crisis. The breasts are a central part of both the physical and the mental self of most women. Aim: To describe women of reproductive age experience of having undergone mastectomy. Methods: A qualitative literature study based on eleven articles with qualitative approach was made. Results: The result shows five themes: Influence of body image, changes in sexual life, influence on mental conditions, the need for assistance to obtain a good quality of life and positive experiences after cancer treatments. Women who underwent mastectomy experienced negative changes in their body image that affected many aspects of life such as sexuality, partnership, parenthood and relationships in their professional life. Clinical implications: The nurse's responsiveness to women and understanding of their physical and psychosocial changes are prerequisites to alleviate women's suffering and promote well-being in spite of breast disease and mastectomy.
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38

Bordallo, Felipe Raqui. "O processo de educação em saúde em um grupo de orientação de alta às mulheres mastectomizadas." Universidade Federal Fluminense, 2013. https://app.uff.br/riuff/handle/1/1091.

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Mestrado Profissional em Enfermagem Assistencial
Introdução: o estudo trata do processo de educação em saúde desenvolvido pelo enfermeiro no grupo de orientação de alta junto às mulheres mastectomizadas. Objetivos: Conhecer o processo de educação em saúde realizado no grupo de orientação de alta pela perspectiva das mulheres mastectomizadas; Identificar os conhecimentos apreendidos pelas mulheres mastectomizadas após o grupo de orientação para alta. Discutir os conteúdos da educação em saúde a partir das demandas apresentadas pelas mulheres mastectomizadas. Construir uma tecnologia educacional no formato de um vídeo para o grupo de orientação de alta, baseado no conhecimento das mulheres mastectomizadas. Metodologia: a base teórica utilizada constitui-se no método de educação de Paulo Freire, associado com o conceito de autocuidado de Orem. Trata-se de um estudo descritivo exploratório de abordagem qualitativa. Os participantes foram 20 mulheres após mastectomia que participaram do grupo de orientação para alta. Resultados: apontaram 3 categorias temáticas: 1-Grupo educativo na perspectiva das mulheres mastectomizadas: espaço de trocas dialógicas; 2-Saberes sobre os cuidados pós-operatórios; 3-Educação em saúde a partir das necessidades apresentadas pelas mulheres mastectomizadas para o cuidado domiciliar. A atividade educativa realizada em grupo foi considerada adequada, proporcionando a construção de novos conhecimentos favoráveis à mulher mastectomizada e puderam influenciar positivamente no autocuidado. Estas foram capazes de descrever alguns cuidados que devem ter após a mastectomia. As dúvidas foram relacionadas aos cuidados pós-operatórios, imagem, à volta às suas atividades de vida diária e a continuidade do tratamento. Conclusão: os saberes não podem ser simplesmente transferidos, mas instigados aos educandos, neste caso, o sujeito-paciente, a serem sujeitos reais na construção e da reconstrução juntamente com o educador, estando ambos inseridos no processo de cuidar e educar em saúde. O grupo atua como espaço de elucidação de dúvidas, de compartilhamento de medos e angústias e de muitas trocas de saberes. Mas há necessidade de revisão da dinâmica do grupo principalmente em relação ao tempo. Desta forma o vídeo educativo pretende contribuir com a dinâmica do grupo, buscando melhorar o processo de educação em saúde com a construção de novos saberes com uma redução no tempo de realização do grupo para que se torne menos cansativo. Assim, o desenvolvimento do vídeo educativo durante o grupo pode facilitar a construção do conhecimento dos cuidados após a mastectomia por se tratar de um material educativo com recursos visuais e auditivos
Introduction : The study deals with the process of health education developed by nurses in the group of orientation with the high mastectomy women. Objectives : To understand the process of health education carried out in the group of high orientation from the perspective of women who underwent mastectomy ; Identify the knowledge learned by women after mastectomy group orientation to high. Discuss the content of health education from the demands made by women with mastectomies . Building an educational technology in a video format for high steering group , based on knowledge of women with mastectomies. Methodology : a theoretical basis is used in the education of Paulo Freire method associated with the concept of self-care Orem . This is a descriptive exploratoryqualitative study. Participants were 20 women after mastectomy who participated in the steering group to high. Results: pointed 3 themes : 1 - Group education from the perspective of women with mastectomies : space dialogical exchanges ; 2 - Knowledge about post- operative care ; 3 - health education based on the needs presented by women who underwent mastectomy for home care . The educational activity conducted in a group was considered adequate , providing the construction of new knowledge favorable to women with mastectomies and could positively influence self-care . These were able to describe some things you should take after mastectomy . The questions were related to postoperative image care, back to their activities of daily living, and continuing care. Conclusion: The knowledge can not simply be transferred , but urged learners , in this case , the subject -patient , to be real actors in the construction and reconstruction along with the teacher , are both entered in the care and health education process. The group operates as answer any questions, fears and anxieties of sharing and exchanging knowledge of many . But there is a need for review of group dynamics especially in relation to time. Thus the educational video intended to contribute to the dynamics of the group , seeking to improve the process of health education with the construction of new knowledge with a reduction in time to accomplish the group so that it becomes less tiring . Thus , the development of educational video during the group can facilitate the construction of knowledge of care after mastectomy because it is an educational material with visual and auditory features
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39

Perez, Carla Silva. "Influência da mastectomia unilateral no equilíbrio estático e na marcha." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/17/17152/tde-25052015-222005/.

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Mulheres submetidas à mastectomia, apresentam assimetrias posturais, assim como alterações na cinemática do movimento do ombro e tronco. O objetivo deste estudo foi avaliar o equilíbrio estático bem como a marcha em mulheres submetidas à cirurgia de mastectomia unilateral. Para tanto, foram analisadas 42 mulheres, divididas em dois grupos: mulheres submetidas à mastectomia unilateral (GM), com idade média de 53,77±7,24 anos, e mulheres sem a doença como controle (GC), com idade média de 54,70±6,31 anos. As análises do equilíbrio estático e da marcha foram efetuadas com sistema Vicon System (VICON-MX-T40S, Oxford, Inglaterra). Foi avaliado o equilíbrio estático com olhos abertos e olhos fechados, com e sem o uso da prótese mamária externa, por meio da área e do deslocamento do centro de massa projetado no chão, assim como o ângulo da coluna. Na marcha, foram avaliados os parâmetros espaço-temporal com e sem o uso da prótese mamária externa, e a oscilação dos membros superiores e do tronco. Foi aplicado o teste de normalidade de Shapiro-Wilk, diante de uma distribuição normal e relacionada, aplicou-se o teste T relacionado, e para amostras independentes, teste T independente, em distribuição não paramétrica, foi aplicado Wilcoxon para variáveis relacionadas e Mann-Whitney, para variáveis independentes. Foi fixado o nível crítico de 5% (p<0,05), o processamento dos dados efetuado pelo software SPSS, versão 17.0. A análise do equilíbrio estático apontou aumento significativo na área e no deslocamento do centro de massa projetado no chão, e deslocamento médio-lateral do ângulo da coluna. Na marcha, houve piora dos parâmetros espaço-temporal e menor oscilção do membro superior homolateral à cirurgia para movimentos de flexão/extensão e abdução/adução, o tronco apresentou menor oscilação médio-lateral. A prótese parece não ter influenciado no equilíbrio e na marcha. Os resultados sugerem que a mastectomia unilateral pode afetar o equilíbrio e a marcha.
Women undergoing mastectomy, have postural asymmetries as well as changes in the kinematics of the movement of the shoulder and spine. The objective of this study was to evaluate static balance and gait in women undergoing unilateral mastectomy surgery. Therefore, 42 women were analyzed, divided into two groups: women who underwent unilateral mastectomy (GM) with a mean age of 53.77 ± 7.24 years, and women without the disease as control (GC) with a mean age of 54.70 ± 6.31 years. Analyses of static equilibrium and gait was performed with Vicon System (MX-T40S-VICON, Oxford, England). We evaluated the static balance with eyes open and eyes closed, with and without the use of external breast prosthesis through the area and the center of mass displacement designed on the floor, as well as the angle of the spine. On the gait were evaluated spatiotemporal parameters with and without the use of external breast prosthesis and the oscillation of the upper limbs and trunk during walking. The functionality of the upper limbs was measured by the DASH questionnaire, and the level of physical activity by IPAQ. We used the Shapiro-Wilk normality test, before a normal and related distribution, we applied the related t test for independent samples and, independent t test, in non-parametric distribution, Wilcoxon was applied to related variables and Mann Whitney test for independent variables was set the critical level of 5% (p <0.05), the processing of data carried out by SPSS software, version 17.0. The static equilibrium analysis indicated a significant increase in the area and the center of mass offset projected on the ground and the medial-lateral displacement of the spine angle. On the march, there was worsening of spatiotemporal parameters and lower swing in arm ipsilateral to surgery for flexion/extension and abduction/adduction, trunk shows less medial-lateral oscillation. The prosthesis seems to have no influence on balance and gait. The results suggest that unilateral mastectomy can affect the balance and gait.
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40

Silva, Rafaella Brito e. "Um estudo de acompanhamento da vivência da dança do ventre como recurso terapêutico com mulheres mastectomizadas." Pontifícia Universidade Católica de São Paulo, 2015. https://tede2.pucsp.br/handle/handle/15463.

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This thesis, which is the result of a personal and professional experience with dancing, as well as of an interest in studies and initiatives in the field of Psycho-oncology, consisted of a follow-up research study based on the theoretical framework of Gestalt Therapy. The aim of the study was to investigate how mastectomized women who underwent a group corporeal intervention, with belly dancing as a therapeutic means, perceived themselves in their corporeality three years after their experience. The importance of this study is related to the need to expand therapeutic strategies for health promotion during the breast cancer post-treatment of mastectomized women. It comprises a qualitative survey in which follow-up interviews were conducted in groups and individually. The analysis and discussion were based on the collaborators' reports, by employing the phenomenological method. It was possible to identify that belly dancing played an important role in copying with the disease and also in the participants' lives. Belly dancing helped to mobilize resources in order to deal with the changes resulting from the treatment, as well as changes in the maturing process. The dance, the music and the movement were perceptible as a trigger for the promotion of contact with femininity and sensuality in a pleasant and ludic way. The therapeutic group was significantly important as an outer support, providing a welcoming space for experiencing the body and for the exchange of experiences. It can be concluded that belly dancing is a potential therapeutic tool in the rehabilitation of mastectomized women in the long term too
Esta tese, fruto de uma experiência pessoal e profissional com dança e do interesse por estudos e ações na área da Psico-Oncologia, consistiu em uma pesquisa de acompanhamento baseada no referencial teórico da Gestalt-Terapia. O objetivo foi investigar como, mulheres mastectomizadas que passaram por uma intervenção corporal grupal com a dança do ventre como recurso terapêutico, se percebem na sua corporeidade três anos após a vivência. A importância desse estudo está relacionada à necessidade de ampliação de estratégias terapêuticas voltadas para a promoção da saúde no póstratamento do câncer de mama de mulheres que foram mastectomizadas. Trata-se de uma pesquisa qualitativa na qual foram realizadas entrevistas de acompanhamento em grupo e individuais. A análise e discussão foram feitas com base no discurso das colaboradoras, pautada no método fenomenológico. Foi possível identificar que a dança do ventre teve um papel importante no enfrentamento da doença e posteriormente na vida das participantes. A dança ajudou a mobilizar recursos para lidar com as mudanças decorrente do tratamento, assim como com as mudanças no processo de amadurecimento. Pudemos perceber a dança, a música e o movimento como um estopim que promove contato com a feminilidade e sensualidade de forma prazerosa e lúdica. O grupo terapêutico foi bastante importante no papel de heterossuporte, propiciando um espaço acolhedor para a vivência do corpo e troca de experiências. Pode-se concluir que a dança do ventre é um possível recurso terapêutico na reabilitação de mulheres mastectomizadas também a longo prazo
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41

Marinho, Vinicius Lopes. "Fatores de risco, proteção e resiliência em mulheres mastectomizadas acompanhadas pela Liga Feminina de Combate ao Câncer de Gurupi-TO." Universidade Federal do Tocantins, 2016. http://hdl.handle.net/11612/460.

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No Brasil, o câncer de mama tem sido a maior causa de óbitos da população feminina, principalmente na faixa etária entre 40 e 69 anos. A mastectomia é o método mais utilizado para tratamento e objetiva a retirada total do tumor. O procedimento causa prejuízos emocionais, sociais e afeta de forma significativa a qualidade de vida da mulher. O estudo teve como objetivo investigar o processo de resiliência em mulheres mastectomizadas. Possui natureza qualitativa, realizado com 10 mulheres acompanhadas pela Liga Feminina de Combate ao Câncer de Gurupi-To. Para a coleta dos dados utilizou-se questionário para caracterização das participantes e entrevista semiestruturada, que foram submetidos à análise de conteúdo de Bardin e organizados em torno de três categorias: sentimentos e vivências diante do diagnóstico e tratamento; fatores de risco, proteção e processo de resiliência. Constatou-se que receber o diagnóstico de câncer de mama trouxe à tona sentimentos como incredulidade por estar doente, raiva, negação, culpa e medo, entretanto, para algumas participantes a vivência significou aprendizado e superação. Os fatores de risco identificados nos relatos foram: dificuldades em acessar a rede de saúde, ausência de apoio da família e amigos, efeitos colaterais durante o tratamento quimioterápico e reações emocionais, presentes desde o diagnóstico até a finalização do tratamento. Já os fatores de proteção foram o suporte da família, amigos e profissionais da saúde; a fé em Deus e espiritualidade; e o trabalho. Compreendeu-se neste estudo que estar resiliente relaciona-se com a capacidade de vivenciar medos, angústias e incertezas, assumindo postura ativa de enfrentamento ao câncer de mama, encontrando novos sentidos para as dificuldades vivenciadas e serem fortalecidas por estas.
In Brazil, the breast cancer has been the major cause of deaths in female population, especially in the age between 40 and 69.The mastectomy it is the most used method aiming to remove the tumor. The procedure cause social and emotional problems and affect significantly the quality of life of the woman .the study aimed to investigate the resilience process the mastectomized women. The study have qualitative nature carried out with 10 women and the league Feminine against Câncer in Gurupi. For the collect of data was done questionnaire to characterize the participant, interview. The result of the interview was submitted to Bardin content and organized in three categories: Feelings and Experience on Diagnosis and treatment, risk factors and protective factors together with resilience process. Receiving the diagnostic of breast cancer, brought feelings like unbelief for being sick, anger, denial, guilt and fear. However, for some, the experience means learning and overcoming state. the risk factors of the survey was absent of the family and friendly support ,side effects during chemotherapy , and sadness and give up feelings sometimes together with fear during the treatment. Otherwise, the protector factors was the family support, friendships and professional support, faith in god and spirituality and the job. She understood in this study that being resilient is related to the ability to experience fears, anxieties and uncertainties, taking an active posture of coping with breast cancer, finding new meanings for the difficulties experienced and being strengthened by them.
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42

Lopes, Sara Luisa Castro Sobral. "Quantificação dos valores da pressão parcial de oxigénio (po2) e da saturação do oxigénio (so2) para caracterização dos níveis de hipoxia no tumor mamário de cadelas : estudo preliminar." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2017. http://hdl.handle.net/10400.5/13433.

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Dissertação de Mestrado Integrado em Medicina Veterinária
Os tumores da mama representam a neoplasia mais frequente na cadela, com uma taxa de malignidade de cerca de 50%. A elevada taxa de proliferação celular verificada no desenvolvimento tumoral, resulta num inadequado aporte de oxigénio a algumas regiões do tumor originando zonas de hipoxia, a qual se relaciona num sistema causa-efeito com o nível de resposta terapêutica dos doentes oncológicos. O estudo presente foi realizado numa amostra de 32 indivíduos (N=32), da espécie Canis familiaris, do género feminino, e teve como objectivo quantificar o valor da pressão parcial de Oxigénio (PO2) e de saturação do Oxigénio (SO2) no débito sanguíneo do tumor mamário de cadelas. A amostra foi dividida em 2 grupos: 1) um grupo controlo (GC), formado por indivíduos saudáveis sujeitos a ovariohisterectomia eletiva, e 2) um grupo estudo (GM), formado por cadelas com tumor mamário e submetidas a mastectomia. Cada individuo foi sujeito a duas colheitas de sangue, por punção nas veias epigástrica superficial caudal da mama e veia safena. A quantificação da PO2 e SO2 foi realizada utilizando o aparelho i-Stat, com o sistema analítico CG4+. A média de PO2 na veia epigástrica caudal foi de 130,1±51,7 mmHg no GC e 166,5±49,9 mmHg no GM, e de 125,2±45,4 no GC e 122,9±60,1 no GM para a PO2 na veia safena. Para a SO2 a média foi de 97,6±3,3% no GC e 94,7±7,6% no GM, na veia safena, e de 97,92±3,5% para o GC e de 92,9±8,4% no GM na veia epigástrica caudal. Consideraram-se os resultados estatisticamente significativos para valores de p <0,05. Não se registaram diferenças estatisticamente significativas entre PO2 de GC e GM (p >0,05) assim como entre a SO2 de ambos os grupos (p >0,05). A dimensão da amostra, e a impossibilidade de medição da PO2 e da SO2 por método de medição intra-tumoral, poderão ter sido os principais factores que influenciaram os resultados obtidos.
ABSTRACT - QUANTIFICATION OF THE PARTIAL OXYGEN PRESSURE (PO2) AND OXYGEN SATURATION (SO2) VALUES FOR THE CHARACTERIZATION OF HYPOXIA IN THE BLOOD FLOW OF MAMMARY TUMOR OF BITCHES - PRELIMINARY STUDY - Mammary tumors represent the most common neoplasia in the bitch, with a malignancy rate of about 50%. The high rate of cell proliferation observed in tumor development results in an inadequate supply of oxygen to some regions of the tumor leading to areas of hypoxia, which is related to a cause-effect system with the level of therapeutic response of cancer patients. The present study was carried out on a sample of 32 individuals (N = 32), of the Canis familiaris species of the female genus, and had as objective to quantify the oxygen partial pressure (PO2) and oxygen saturation (SO2) in the blood flow of mammary tumor of bitches. The sample was divided into 2 groups: 1) a control group (CG), formed by healthy individuals subject to elective ovariohysterectomy, and 2) a study group (GM), formed by patients with mammary tumor and submitted to mastectomy. Each individual was subjected to two blood collections by puncture in the caudal superficial epigastric veins and saphenous vein. The quantification of PO2 and SO2 was performed using the i-Stat apparatus with the CG4 + analytical system. The mean PO2 in the caudal epigastric vein was 130.1 ± 51.7 mmHg in the CG and 166.5 ± 49.9 mmHg in the GM, and 125.2 ± 45.4 in the GC and 122.9 ± 60, 1 in GM for PO2 in the saphenous vein. For SO2 the mean was 97.6 ± 3.3% for GC and 94.7 ± 7.6% for GM, saphenous vein, and 97.92 ± 3.5% for GC and 92, 9 ± 8.4% in GM in the caudal epigastric vein. The results were statistically significant for p values <0.05. There were no statistically significant differences between PO2 of GC and GM (p> 0.05) as well as between SO2 of both groups (p> 0.05). The size of the sample and the impossibility of measuring PO2 and SO2 by intra-tumor measurement method may have been the main factors that influenced the results obtained.
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Ferreira, Vânia Tie Koga. "Influência da dor miofascial sobre a qualidade de vida e a postura em mulheres submetidas ao tratamento do câncer de mama." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17152/tde-06012017-114133/.

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A dor crônica que afeta mulheres submetidas ao tratamento do câncer de mama envolve o componente muscular relacionado com a dor miofascial, e está é caracterizada, sobretudo, pela presença de pontos gatilhos miofasciais. O objetivo do presente estudo foi correlacionar a dor miofascial crônica mensurada por meio intensidade de dor, limiar de dor à pressão e catastrofização com a qualidade de vida, postura, distribuição da pressão plantar e temperatura cutânea, em mulheres submetidas ao tratamento do câncer de mama. Para tanto, foram incluídas no estudo 40 mulheres submetidas ao tratamento do câncer de mama, com média de idade de 54,71±14,00 anos, e queixa de dor na região do tronco superior, com ponto gatilho miofascial ativo e de localização central no músculo trapézio fibras descendentes. Foram empregadas na avaliação a escala numérica de dor, algometria, escala de pensamentos catastróficos sobre dor, termografia infravermelha, qualidade de vida, avaliação postural e baropodometria. A análise estatística foi apresentada por meio de medidas de tendência central e dispersão. A distribuição dos dados foi verificada por meio do teste de Shapiro-Wilk. Foi considerado o coeficiente de correlação de Pearson (r) para a associação de variáveis paramétricas e, para variáveis não paramétricas, foi empregado o coeficiente de correlação de Spearman (rs). Foram observados os seguintes resultados significativos: negativa associação entre a qualidade de vida e intensidade de dor (rs = - 0,400, p = 0,031); negativa associação entre a qualidade de vida e catastrofização (rs = - 0,472, p = 0,010); positiva associação entre a qualidade de vida e o limiar de dor à pressão do lado operado (r = 0,329, p = 0,038); positiva associação entre o ângulo da cifose torácica e a intensidade de dor (rs = 0,321, p = 0,044); e negativa associação entre o ângulo de protrusão cervical e o limiar de dor à pressão do lado operado (rs = -0,474, p = 0,002) e do lado não operado (rs = -0,454, p = 0,003). A dor miofascial em mulheres que foram submetidas ao tratamento do câncer de mama gera redução na qualidade de vida e alterações posturais, com aumento dos ângulos da cifose torácica e de protrusão cervical.
Chronic pain that affects women undergoing treatment for breast cancer involves the muscular component of myofascial pain, characterized by the presence of myofascial trigger points. The aim of this study was to correlate chronic myofascial pain, measured by means of pain intensity, pressure pain threshold and pain catastrophizing with quality of life, posture, plantar pressure distribution and skin temperature in women undergoing treatment for breast cancer. The study included 40 women undergoing treatment for breast cancer, with a mean age of 54.71±14.00 years, complaints of pain in the upper body region, with active myofascial trigger point centrally located on the descending fibers of the trapezius muscle. The Numeric Pain Scale, algometry, the Pain Catastrophizing Scale, infrared thermography, quality of life, postural assessment and baropodometry were used. Statistical analysis was presented by means of central tendency and dispersion measurements. Distribution of the data was verified by means of the Shapiro-Wilk test. For association of parametric variables, Pearson\'s correlation coefficient (r) was applied, and Spearman\'s correlation coefficient (rs) was used for nonparametric variables. The following significant results were observed: negative association between quality of life and pain intensity (rs = -0.400, P = 0.031); negative association between quality of life and pain catastrophizing (rs = -0.472, P = 0.010); positive association between quality of life and the pressure pain threshold on the operated side (r = 0.329, p = 0.038); positive association between the angle of thoracic kyphosis and pain intensity (rs = 0.321, p = 0.044); and negative association between the cervical protrusion angle and pressure pain threshold on the operated side (rs = -0.474, P = 0.002) and the non-operated side (rs = -0.454, P = 0.003). Myofascial pain in women who underwent treatment for breast cancer leads to a reduction in quality of life and postural changes, with increased angles of thoracic kyphosis and cervical protrusion.
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44

Lindqvist, Rikard. "Hospital length of stay : register-based studies on breast-cancer surgery /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-312-4/.

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45

Bonfim, Isabela Melo. "Significado do cuidado familiar à mulher mastectomizada." Universidade Federal do CearÃ, 2005. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=5597.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior
O cÃncer de mama costuma ser motivo de receio entre as mulheres e para a sociedade, em geral. A simples pronÃncia da palavra cÃncer gera na populaÃÃo feminina sentimentos de medo, tristeza, ansiedade e negaÃÃo, devido ao elevado Ãndice de morbimortalidade e tambÃm de mutilaÃÃo decorrente da doenÃa, que sempre compromete a auto-estima, a interaÃÃo social, os relacionamentos afetivos e a vida profissional de quem à acometido. Portanto, conhecer de que modo lidam com o fato de terem um familiar com neoplasia mamÃria, foi a inquietaÃÃo que motivou a realizaÃÃo deste estudo, que teve como objetivos desvelar os significados que as famÃlias de mulheres mastectomizadas constroem e que orientam suas aÃÃes ao cuidar delas e apresentar um modelo teÃrico acerca do cuidado prestado pelas famÃlias à mulher mastectomizada. Trata-se de um estudo descritivo com abordagem qualitativa que utilizou como referencial teÃrico o Interacionismo SimbÃlico e a Teoria Fundamentada em dados Grounded Teory como referencial metodolÃgico. A coleta de dados aconteceu no mÃs de julho de 2008, em uma instituiÃÃo de referÃncia no tratamento do cÃncer. Utilizamos como estratÃgia para a coleta de dados, a entrevista com onze familiares de mulheres mastectomizadas. Obtivemos, entÃo, os dados que apÃs a anÃlise, permitiram a criaÃÃo da teoria central: Significado do cuidado familiar à mulher mastectomizada, a qual constitui-se de fenÃmenos distintos que se inter-relacionam: CompreensÃo da famÃlia sobre a mastectomia, que se caracteriza revelando como a famÃlia se sente diante de um familiar com cÃncer e ao cuidar de uma mulher mastectomizada; as dificuldades da famÃlia para cuidar, cuja finalidade à demonstrar as mudanÃas ocorridas na famÃlia, sejam elas, financeiras ou no papel social familiar modificado; compreendendo o diagnÃstico de cÃncer na famÃlia, em que se percebe a dimensÃo do impacto do diagnÃstico do cÃncer de mama, atingindo nÃo somente a mulher, mas todo o seio familiar e o cuidado familiar apÃs a cirurgia, que enfatiza como mulher e famÃlia buscam superar as limitaÃÃes enquanto pessoas interagindo no grupo familiar acometido pelo cÃncer de mama. Em nossa opiniÃo, o cuidado em famÃlia requer o envolvimento verdadeiro e afetuoso, envolver-se e acreditar que sua presenÃa à tÃo importante quanto à realizaÃÃo de procedimentos tÃcnicos. Como ressaltamos, nem sempre os conhecimentos tÃcnicos objetivos funcionam tÃo bem diante de situaÃÃes de estresse como os conhecimentos subjetivos que se revelam na dinÃmica familiar.
The breast cancer used to be reason of fear between the women and in all the society, in general. The simple pronunciation of the word cancer, already generates in the feminine population feeling of fear, sadness, anxiety and negation, which had to the raised index of morbid-mortality and also of decurrent mutilation of the illness, that always compromises the auto-esteem, the social interaction, the affective relationships and the professional life of who it is under attack. It enters the familiar ones of the patients with cancer, is not different. The feelings and reactions generated ahead of the confirmation of if having a relative with mammary neoplasms, cause a series of feelings that many times modify all the familiar dynamics. The doubts, questionings, changes of papers and alterations in the routine of the family, are frequent and many times, the psychological unpreparedness to deal with the new condition of the dear person, bring doubts and frustrations. Therefore, to know of that way these families deal with the fact of if having a with mammary neoplasms, it was the fidget that motivated the accomplishment of this study, that had as objectives to discovering the meanings that the families of mastectomized women construct and that they guide its action when taking care of it and to present a theoretical model concerning the care given for the families to the mastectomized woman. One is about a descriptive study with qualitative boarding that it used as review theoretician the Symbolic Interactionism and the Theory Based on data Grounded Teory as frameworks metodological. The collection of data happened in the month of July of 2008, in an institution of reference in the treatment of the cancer. We use as strategy for the collection of data, the interview with eleven family caregivers ones of mastectomized women. We got then, the data that after the analysis, had allowed the creation of the central theory: Meaning of the familiary care to the mastectomized woman, which consists of distinct phenomena that if across: Understanding of the family on the mastectomy, that it is characterized disclosing as the family if it feels ahead of a family caregivers one with cancer and when taking care of a mastectomized woman; The difficulties of the family to take care of, whose purpose is to demonstrate the occured changes in the family, are they, financial or in the modified familiar social paper; Understanding the diagnosis of cancer in the family, where it is perceived dimension of the impact of the diagnosis of the breast cancer, reaching not only the woman, but all the familial sinus and the familiar care after the surgery, that emphasizes as woman and family searchs to surpass the limitations while people interacting in the familiar group under attack by the breast cancer. In our opinion, the care in family requires the true and affectionate envolvement, to become involved themselves and to believe that its presence is so important how much the accomplishment of procedures technician. As we stand out, nor always the objective knowledge technician function so well ahead of situations of stress as the subjective knowledge that if disclose in the familiar dynamics.
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46

Johansson, Linus Somsak, and Josefin Lindqvist. "Experience of quality of life among women who have undergone breast reconstruction after mastectomy." Thesis, Kristianstad University College, Department of Health Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-4502.

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Background: In Sweden around 6500 women suffer each year from breast cancer and during lifetime every tenth women is affected. Mastectomy (removal of part of or the whole breast) is carried out mostly in purpose to remove malign tumours or in prophylactic purpose. The breast can be rebuilt through breast reconstruction. Method: The result analysis was based on nine articles. A Manifest content analysis was used and data from the articles where divided into themes and patterns, on the basis of these categories were created. Aim: The aim of this study was to describe women’s experience of quality of life which has undergone breast reconstruction after mastectomy. Results: The result is presented in categories: psychic, social, physical, body image and sexual. After breast reconstruction women can suffer from psychological, social, physical, body image and sexual dysfunctions. Women’s quality of life after breast reconstruction varies. Women should in right time receive support from medical staff. Body image, body reality and self-image are affected by illness. A good body image can improve self-confidence which can improve quality of life. Conclusion: Participations and awareness can be linked to good quality of life after breast reconstruction. Therefore information is an important foundation stone in the care.

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47

Binns-Turner, Pamela Gail. "Perioperative music and its effects on anxiety, hemodynamics, and pain in women undergoing mastectomy." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008d/binns-turner.pdf.

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48

Silvestri, Ana. "A holistic approach to care for women struggling after mastectomy : an interpretative phenomenological analysis." Thesis, City, University of London, 2019. http://openaccess.city.ac.uk/21676/.

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Background: Breast cancer is the most prevalent type of cancer among women worldwide today. Although the number of diagnosed cases continues to increase, the efficacy of treatment has also been improving, allowing survival rates to rise. Breast cancer treatment and surgery often involve a variety of changes in women's appearance, altered sense of identity and relational challenges. A limited amount of research has been found in connection to the subjective embodied experience of women after mastectomy and during rehabilitation. Purpose: The aim of the present study was to conduct an idiographic exploration of the participants' perceptions of physical and psychological struggles after mastectomy relating to identity change, self-image and sexual intimacy and how these were embodied in the context of overall wellbeing after illness. Method: This research sought to explore in depth participants' subjective experiences of femininity and sexuality after mastectomy using Interpretative Phenomenological Analysis (IPA) through semi-structured individual interviews. Results: Three major themes emerged from the data: (1) the 'Ill Self', (2) the 'Vulnerable Self' and (3) the 'Coping Self'. Nine sub-themes emerged from the data: (1) 'shock', 'pain', 'body-changes', (2) 'control', 'uncertainty', 'other's gaze', (3) 'warrior', 'comparing losses' and 'recovering'. The themes illustrate a linear but complex experience of women losing their healthy status and functioning to becoming breast cancer patients, and through to recovery. The first major theme ‒ 'Ill Self' ‒ includes participants' responses to physical and psychological experiences in the context of illness. Participants expressed the difficulties faced in this first stage of diagnosis and how that seemed to have shifted their position from being healthy to becoming a patient. This major theme reflects participants' views on interactions with their bodies and how these are expressed through self-image as they lose/gain body parts (mastectomy and/or reconstruction). The second major theme ‒ 'Vulnerable Self' ‒ was identified through participants' exposed vulnerability in relational dynamics but also vulnerability to the challenges presented by illness. Participants revealed conflicts with others and themselves in surrendering and taking power. The 'Vulnerable Self' also illustrates women's concerns about the uncertainties regarding the recovery process and their feelings of exposure to the other's gaze during rehabilitation. The third major theme - 'Coping Self' ‒ is the final identity recognised in the data. I identified the participants' need to gather their remaining emotional resources following a phase of high vulnerability and to continue their journey into recovery and the reestablishment of wellbeing. My findings explicitly show the need to create a strong professional network of support between counselling psychologists and other relevant healthcare professionals. This network of support relies on the close involvement of clients during assessment and formulation. Designing a holistic treatment plan which is based on individual client needs (identity, relationships, sexual recovery, body image, etc.) but which also accounts for the physical and psychological needs of service users is paramount for the recovery of quality of life after breast cancer. Conclusion: The findings of this study add to the body of research regarding women's struggles after mastectomy and the embodiment of illness. Participants reported their perceptions and reactions regarding identity change, self-image and sexual intimacy after mastectomy. The participants' desire for a holistic approach to care from specialised services during treatment and recovery was noted. A shortcoming in terms of the provision of psychotherapeutic services to facilitate sensitive communication and follow up on the recovery of breast cancer patients was identified within medical teams, at times of extreme physical and psychological struggle for participants.
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Fabian, Tania, and Caroline Fredriksson. "Kvinnors beslutsfattande vid profylaktisk mastektomi : En litteraturstudie." Thesis, Högskolan i Halmstad, Akademin för hälsa och välfärd, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-41349.

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Bakgrund: Profylaktisk mastektomi är en behandling där brösten avlägsnas kirurgiskt i förebyggande syfte. Det finns olika indikationer till att profylaktisk mastektomi övervägs. Begreppet beslutsfattande kräver förståelse för att kunna beskriva kvinnors beslut vid profylaktisk kirurgi med anledning av att den individuella osäkerheten kring behandlingsval ska minska. Information och stöd är viktiga aspekter för en sjuksköterska att ge för att främja patientens integritet, självbestämmande och delaktighet. Syftet med litteraturstudien var att beskriva faktorer relaterade till beslutsfattandet hos kvinnor vid profylaktisk mastektomi. Metoden som användes var en allmän litteraturstudie med induktiv ansats där tio vetenskapliga artiklar med anknytning till aktuellt syfte valdes ut för att utforma ett resultat. Resultatet utmynnade i tre olika kategorier varav en med två underkategorier och en med tre underkategorier. Oro, föräldraskap, genmutation och upplevelse av information visade sig influera beslutsfattandet. Få skillnader i beslutsfattandet påvisades mellan kvinnor som var bärare och ickebärare av genmutation. Konklusion: Kvinnor som stod inför ett beslutsfattande vid profylaktisk mastektomi var alla egna individer och hade därmed olika preferenser i avseende behov av stöd, delaktighet i beslutsfattandet, mottagandet av information samt vad som influerat beslutet. Vårdprofessionella ska presentera adekvat, evidensbaserad samt enhällig information för att underlätta kvinnors beslutfattande.
Background: Prophylactic mastectomy is a treatment where the breasts are surgically removed for preventive purposes. There are various indications why prophylactic mastectomy is being considered. Understanding the concept of decision making is required to describe women’s decision about prophylactic surgery in order to reduce individual uncertainty about treatment choices. Information and support are important aspects for a nurse to provide in order to encourage patient integrity, self-determination and participation. The aim of this literature study was to describe factors related to decision making among women regarding prophylactic mastectomy. The method was a literature study with an inductive approach. Ten scientific articles related to the current purpose were selected to form a result. The result emerged in to three different categories, one with two subcategories and one with three subcategories. Concerns, parenting, gene mutation and experience of information were found to influence the decision making. Few differences in decision making were detected between women who were carriers and non-carriers of gene mutation. Conclusion: Women who faced a decision making in prophylactic mastectomy were all individuals and there for had different preferences regarding need for support, participation in decision making, receiving information and what influenced the decision. Health care professionals should present adequat, evidence based and unanimous information to ease women’s decision making.
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50

Kasper, Priscila Natasha. "ASPECTOS EVOLUTIVOS DE NEOPLASMAS MAMÁRIOS EM CADELAS NOS DIFERENTES TRATAMENTOS CIRÚRGICOS: ESTUDO RETROSPECTIVO." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/10206.

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Abstract:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Mammary tumors are the most common type among those tumors in dogs, where approximately 50% are malignant. The etiologies of these neoplasms are still quite controversial, however, it is known that tumors of malignant origin have high ability to spread among the targets, inguinal and axillary lymph nodes, and the breast parenchyma. The type of therapy can be modified using traditional therapies such as anticancer chemotherapy, electrochemotherapy, metronomic chemotherapy, radiotherapy or surgical. The surgery effectively in curing about 50% of malignant tumors. What has been widely discussed in recent years is how to surgical resection used for removal of breast neoplasms influence the high rates of tumor recurrence. The current literature recommend that make surgical removal of the chain affected mammary glands, along with all associated lymphatic tissue, thereby improving the prognosis of patients. However, stresses the importance of the development of predictive evaluation criteria in an attempt to achieve better surgical planning with broader approaches and free of tumor cells. This study was conducted at the Veterinary Hospital of the Federal University of Santa Maria, with 502 bitches with breast neoplasms and were subjected to some type of surgical procedure for correction. We conducted a post-surgical study using a questionnaire based on questions and answers related to the type of procedure performed, realization of ovariohysterectomy and postoperative recurrence percentages. In the survey it was observed that the surgical techniques of total bilateral mastectomy ( 11%) and total unilateral mastectomy (17%) had lower percentages of recurrence when compared to regional mastectomies ( 75%) and lumpectomies ( 83%). After the results of the questionnaire, there was a pilot study with 6 bitches presenting breast neoplasms, aiming at a proposed new surgical technique for the treatment of breast neoplasms in dogs, taking into account the results collected and some principles of surgery oncology established.
As neoplasias mamárias constituem o tipo mais comum dentre os tumores em cadelas, onde aproximadamente 50% são malignos. As etiologias dessas neoplasias ainda são bastante controversas, porém, sabe-se que os tumores de origem maligna possuem elevada capacidade de disseminação entre os linfonodos sentinelas, inguinais e axilares, e o parênquima mamário. O tipo de terapia pode variar entre quimioterapia antineoplásica, eletroquimioterapia quimioterapia metronômica, radioterapia ou de forma cirúrgica, sendo a cirurgia eficaz na cura de cerca de 50% dos tumores malignos. O que vem sendo amplamente discutido nos últimos anos é a forma de ressecção cirúrgica utilizada para remoção dos neoplasmas mamários e sua influência nas altas taxas de recidivas tumorais. A literatura atual recomenda que se faça a remoção cirúrgica da cadeia de glândulas mamárias afetadas, juntamente com todo o tecido linfático associado, melhorando assim o prognóstico dos pacientes. Porém, frisa-se a importância do desenvolvimento de critérios de avaliação preditivos na tentativa de alcançar melhor planejamento cirúrgico com abordagens mais amplas e livres de células tumorais. O presente estudo foi realizado no Hospital Veterinário Universitário da Universidade Federal de Santa Maria, com 502 cadelas portadoras de neoplasmas mamários e que foram submetidas a algum tipo de procedimento cirúrgico para sua correção. Realizou-se um estudo pós-cirúrgico utilizando um questionário baseado em perguntas e respostas relacionadas ao tipo de procedimento executado, realização da ovário-histerectomia e porcentagens de recidivas pós-operatórias. No levantamento realizado foi observado que as técnicas cirúrgicas de mastectomia total bilateral (11%) e mastectomia total unilateral (17%) apresentaram menores porcentagens de recidiva tumoral quando comparadas às mastectomias regionais (75%) e lumpectomias (83%). Após os resultados do questionário, realizou-se um estudo piloto com 6 cadelas apresentando neoplasmas mamários, visando uma nova proposta de técnica cirúrgica realizada para o tratamento dos neoplasmas mamários em cadelas, levando em consideração os resultados coletados e alguns princípios de cirurgia oncológica já estabelecidos.
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