Dissertations / Theses on the topic 'Marmoset'
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Young, Fiona Margaret. "Luteal regression in the marmoset monkey." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/23277.
Full textKühnel, Friederike. "Erhebung von Blutrichtwerten und deren Beeinflussung durch Haltung und Fütterung beim Weißbüschelaffen (Callithrix jacchus)." Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-129437.
Full textCommon marmosets are often used as animal models for human diseases. For their health maintenance, diagnostic blood values are absolutely essential. Previously obtained reference values are characterized by great value-specific differences. Moreover, the influence of routine measures on these blood parameters, e. g. changes in housing conditions, has not been examined yet. Therefore, the first aim of the present study was to update haematological and clinical chemical blood parameters of common marmosets. Further, the influence of stress, caused by relocation to a new housing, on these parameters and the cortisol level in feces was examined. In addition to that, common marmosets under human management are often affected by gastrointestinal diseases, which are difficult to diagnose with basic standard blood values. In this context, sensitivity to nutritional elements, e. g. gluten, plays an important role and is discussed as a potential cause of wasting marmoset syndrome (WMS). In the second part of this study, the recurrent gastrointestinal diseases of common marmosets under human management were aetiologically investigated, with special regard to possible gluten sensitivity. In the first part of this study, blood samples were obtained from 54 female and male common marmosets to evaluate standard values of haematology and clinical chemistry. The determined haematological parameters are similar to the already obtained data, the clinical chemistry values differ somewhat: The enzyme activities of lactate dehydrogenase, alanine aminotransferase and lipase in addition to the ranges of alkaline phosphatase and total bilirubin diverge from the data ascertained in this study. Moreover, female animals presented significantly higher mean corpuscular volume and mean corpuscular haemoglobin than males, whereas male common marmosets showed significantly higher total- and low density lipoprotein-cholesterol, compared to females. Further, 16 animals were relocated to a new environment for a time period of four weeks, before they returned to their home cages. The change of housing caused a decreased leuko- and lymphocyte count in all examined animals that was still measurable four weeks after the relocation. At the same time, an increased fecal cortisol level was determined. The aim of the second study was to investigate the modification of plasma antibodies to gliadin (AGA), tissue transglutaminase (tTG), deamidated gliadin (ADGA) and glycoprotein 2 (AGP2A) during two successive diets in 24 animals: A gluten-containing diet (diet 1) and a gluten-free diet (diet 2). Further, clinical symptoms of WMS and the animals’ body weight were also examined. An analysis of the feces of antibody-positive animals regarding changes in quality and dry matter content was carried out with samples collected during diet 2 and a successive gluten challenge diet of two months duration. The serological diagnostics resulted in a significant decline of AGA, antibodies to tTG and AGP2A during diet 2 in animals that had shown increased antibody concentrations during diet 1. Diet 2 also caused an amelioration of clinical symptoms and an increased body weight in antibody-positive animals. The gluten challenge resulted in a decreased feces quality and a lower fecal dry matter, compared to fecal samples of diet 2. In the context of this dissertation, parameters of haematology and clinical chemistry of the common marmoset were updated. Stress caused by relocation to a new housing was still measurable for a period of four weeks. It is therefore essential to consider this time span in the design of scientific studies to secure animal welfare prior to the study and to reduce the influence of stress on experimental results. In combination with the clinical symptoms, the detection of antibodies that are part of the pathogenesis of coeliac disease in humans strongly suggests gluten sensitivity with an aetiological connection to WMS in common marmosets. Therefore, gluten-free nutrition of common marmosets under human management is highly recommendable
Wagner, Wencke M. "Diagnostic imaging of the normal common marmoset (Callithrix jacchus)." Diss., University of Pretoria, 2004. http://upetd.up.ac.za/thesis/available/etd-06282005-111803/.
Full textZöller, Martina. "Pathogenetische Untersuchungen zum Wasting-Marmoset-Syndrom bei Weissbüschelaffen (Callithrix jacchus)." Giessen DVG-Service, 2005. http://deposit.d-nb.de/cgi-bin/dokserv?idn=978259653.
Full textDias, R. "Functional organisation of the prefrontal cortex of the common marmoset." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598525.
Full textDalrymple, Annette. "Prolactin receptor expression and signalling in the marmoset monkey uterus." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/23319.
Full textBogner, Katja. "Untersuchungen zur Lokalisation und Funktion von ZP-Proteinen im Marmoset-Modell." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976072076.
Full textCooke, Brian Roger. "The marmoset as a potential surrogate for human in drug development." Thesis, University of Surrey, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.521715.
Full textSeehase, Sophie [Verfasser]. "Marmoset monkeys as a preclinical model in respiratory research / Sophie Seehase." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2013. http://d-nb.info/1030452954/34.
Full textDavy, C. W. "Studies on some enzymes of diagnostic interest in the marmoset liver." Thesis, University of Hertfordshire, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382216.
Full textBarbier-Kuyas, Aysegül. "The lung of the marmoset (Callithrix jacchus): ultrastructure and morphometric data /." [S.l : s.n.], 1994. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
Full textAshworth, Jonathan F. "Immunohistochemical study of marmoset periodontal ligament microvasculature : a confocal laser scanning microscopic study." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09DM/09dma831.pdf.
Full textWinkelmann, Julia Marie [Verfasser]. "Nierenveränderungen bei Weißbüschelaffen (Callithrix jacchus) mit Wasting Marmoset Syndrom / Julia Marie Winkelmann." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2010. http://d-nb.info/100966011X/34.
Full textJones, Belinda Sumner. "Vocal behaviour of the common marmoset : structure and function of selected calls." Thesis, Royal Holloway, University of London, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297086.
Full textRonacher, Katharina. "Internalisation of the type II gonadotropin-releasing hormone receptor of marmoset monkey." Doctoral thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/8599.
Full textThe mammalian type II GnRH receptor has a C-terminal tail unlike the mammalian type I GnRH receptor, which uniquely lacks the cytoptasmic C- terminal domain. lnternalisation of a mammalian type ll GnRH receptor has never been investigated, therefore this thesis studies the internalisation pathway of the type ll GnRH receptor. As the C-terminal tail mediates rapid internalisation of many G protein-coupled receptors this research investigates the functional role of the C-terminal tail and intracellular loop in receptor internalisation. The internalisation pathway of the type ll GnRH receptor in COS-1 cells was investigated by co expressing dominant negative mutants and wild- type constructs of G protein-coupled receptor kinases (GRKs), dynamin-1 and β-arrestin 1 and 2 with the type II GnRH receptor. The results show that internatisation of the receptor requires GRK 2 and dynamin but does not require β-arrestin 1 and 2. Furthermore, inhibitors to both the caveolae pathway as well as the clathrin coated vesicle endocytosis abolished receptor internalisation indicating that both structures are involved in internalisation of the receptor. Even though in COS-1 cells the type ll GnRH receptor internatises in a β-arrestin independent manner, internalisation of this receptor can be enhanced by over-expression of wild type β-arrestin. This indicates that the type ll GnRH receptor is able to utilise a β-arrestin mediated internaltsation pathway if high levels of β-arrestin are present in the cell. The mammalian type ll GnRH receptor internalises with enhanced rate and extent compared to the tail-less human type I GHRH receptor. The role of the C-terminal tail of the type ll GnRH receptor in internalisation was investigated by measuring internalisation of C-terminally truncated mutants. It was found that the region between Gly 343 and Ser 335 within the C-terminal domain is important for receptor internalisation. Substitution of putative phosphorylation sites within this region revealed that Ser 338 and Ser 339 are critical for rapid receptor internalisation. Furthermore a serine residue in intracellular loop three (Ser 251) was shown to play a role in signalling as well as in internalisation. Since dominant negative GRK 2 could not inhibit internalisation of a mutant lacking all three serine residues, but could reduce internalisation of the wild-type receptor, we suggest that Ser 251, 338 and 339 are target of phosphorylation by GRK. However these phosphorylation sites as well as the C-terminal tail are not necessary for β-arrestin dependent internalisation. Taken together this thesis elucidates the internalisation pathway of a mammalian type lI GnRH receptor and identified residues within the C-terminal tail and intracellular loop three that are critical for rapid internalisation.
Gameau, Louise J. "The effect of cytokines on chorionic gonadotrophin expression in the marmoset monkey embryo /." Title page, contents and summary only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phg192.pdf.
Full textJackson, Stacey Anne Winifred. "Modelling the neuropsychopharmacology of obsessive-compulsive disorder in the common marmoset (Callithrix jacchus)." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/288835.
Full textGraham, Bryan. "Optical factors affecting post-natal growth of the Marmoset (Callithrix jacchus jacchus) eye." Thesis, University of Oxford, 1996. http://ora.ox.ac.uk/objects/uuid:efdf1daf-f853-4f35-bf55-7df9a32c6a50.
Full textLee, David. "A scanning electron microscopic study of the marmoset palate and periodontium microvasculature using corrosion casts /." Title page, contents and summary only, 1988. http://web4.library.adelaide.edu.au/theses/09DM/09dml477.pdf.
Full textBloomfield, Kelly Louise, and n/a. "Investigation of the Role of Thioredoxin in the Invasive Phenotype and its Interaction with the Transcription Factor Sp1." Griffith University. School of Biomolecular and Biomedical Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20031021.120018.
Full textBloomfield, Kelly Louise. "Investigation of the Role of Thioredoxin in the Invasive Phenotype and its Interaction with the Transcription Factor Sp1." Thesis, Griffith University, 2003. http://hdl.handle.net/10072/366170.
Full textThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Biomedical Sciences
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Zöller, Martina [Verfasser]. "Pathogenetische Untersuchungen zum Wasting-Marmoset-Syndrom bei Weißbüschelaffen (Callithrix jacchus) / vorgelegt von Martina Zöller." Gießen : DVG-Service, 2005. http://d-nb.info/978259653/34.
Full textClarke, Hannah Frances. "The role of serotonin in the prefrontal cortex of the common marmoset (Callithrix jacchus)." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597738.
Full textWallis, Jonathan David. "Functions of the orbital and medial prefrontal cortex of the common marmoset (Callithrix jacchus)." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621700.
Full textPears, Andrew. "Functions of the orbital and medial prefrontal cortex of the common marmoset (Callithrix jacchus)." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620719.
Full textFerrari, Stephen Francis. "The behaviour and ecology of the buffy-headed marmoset, Callithrix flaviceps (O. Thomas, 1903)." Thesis, Online version, 1988. http://ethos.bl.uk/OrderDetails.do?did=1&uin=uk.bl.ethos.284007.
Full textLloyd, S. A. C. "The neural control of masculine reproductive and social behaviours in the common marmoset (Callithrix jacchus)." Thesis, University of Edinburgh, 1989. http://hdl.handle.net/1842/19056.
Full textTkachenko, Olena [Verfasser]. "In vitro oocyte maturation and embryo production in the common marmoset (Callithrix jacchus) / Olena Tkachenko." Berlin : Freie Universität Berlin, 2012. http://d-nb.info/1027151639/34.
Full textLefeuvre, Jennifer. "Characterization of spinal cord lesions in the marmoset EAE model using MRI and histopathology techniques." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS208.
Full textUp to 90% of multiple sclerosis (MS) patients present spinal cord lesions. Magnetic resonance imaging (MRI) of spinal cord lesions is still a difficult challenge. Consequently, the evolution of spinal cord lesions in MS and their contribution to disease progression remain poorly understood. The brain of common marmoset with experimental autoimmune encephalomyelitis (EAE) displays closer radiological and pathological features as well sensori-motor deficits with MS. The objective of this thesis was to develop new MRI protocols at 7 Tesla in association with histopathological analysis to better characterize the type of spinal cord lesions in the marmoset EAE, and to understand their spatiotemporal evolution. A first postmortem study demonstrated a strong resemblance to MS focal lesions in terms of shape and distribution, as well a heterogeneous subpial pathology between animals and along the spinal cord length. Secondly, we implemented a robust in vivo experimental setup in order to adapt to the morphology of the animals and created a 12-element phase-array coil. This new setup enabled us to image for the first time the entire spinal cord of nonhuman primates with EAE during the disease. We also found a strong association between the lesion load and the disability scores. These new findings highlight the relevance of the spinal cord lesions in the marmoset EAE model for studying the disease mechanisms of spinal cord lesions in MS
Uhl, Dorothee. "Untersuchung zur funktionellen Bedeutung von VDAC in weiblichen Gameten des Rindes und des Marmoset-Affen." Giessen : VVB Laufersweiler, 2008. http://d-nb.info/989910423/34.
Full textHauser, Jonas. "Long-term neuro-behavioural effects of prenatal dexamethasone treatment in Wistar rats and marmoset monkeys." kostenfrei, 2007. http://e-collection.ethbib.ethz.ch/view/eth:30028.
Full textShiba, Yoshiro. "Characterising trait anxiety in the common marmoset (Callithrix jacchus) : investigations into behavioural, psychophysiological and cognitive phenotypes." Thesis, University of Cambridge, 2013. https://www.repository.cam.ac.uk/handle/1810/256092.
Full textBerry, Louise. "Vocalizations and communication with a common marmoset (Callithrixjacchus jacchus) family group to food and novel objects." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/mq39173.pdf.
Full textSpacco, Jaime W. "Marmoset a programming project assignment framework to improve the feedback cycle for students, faculty and researchers /." College Park, Md. : University of Maryland, 2006. http://hdl.handle.net/1903/4095.
Full textThesis research directed by: Computer Science. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
Reekie, Yvonna Louise. "Sweet expectations : a neural and psychophysiological analysis of positive 'emotion' in the common marmoset (Callithrix jacchus)." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613180.
Full textBarnes, N. J. G. "Behavioural and biochemical consequences of persistently disturbing cerebral dopamine function in the common marmoset (Callithrix jacchus)." Thesis, University of Bradford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374912.
Full textParlange, Louise Maureen. "A T.E.M. stereological analysis of blood vessels and nerves in marmoset periodontal ligament following orthodontic extrusion /." Title page, table of contents and summary only, 1991. http://web4.library.adelaide.edu.au/theses/09DM/09dmp252.pdf.
Full textLe, Friec Alice. "Evolution of corticospinal tract integrity in stroked marmoset monkeys : Towards a bioimplant and stem cell therapeutic strategy." Thesis, Toulouse 3, 2020. http://www.theses.fr/2020TOU30031.
Full textIschemic stroke frequently damages brain regions involved in the control of voluntary movement and remains a leading cause of adult-acquired disability. Although hundreds of therapeutic strategies have shown potential benefits in animal models of stroke, motor rehabilitation and physiotherapy remain the only validated treatments in Humans after the acute phase. This observation highlights the need to develop and characterize reproducible pre-clinical models, which will allow the assessment of experimental therapies. The first objective of this work was therefore to characterize the anatomical and functional consequences of a brain lesion induced by stereotaxic injection of malonate, a mitochondrial toxin, in rodents and primates. Multimodal Magnetic Resonance Imaging allowed longitudinal non-invasive assessment of tissue alterations. We then performed histological analyses to further describe tissue damage. Motor deficits and their recovery were evaluated using a battery of sensorimotor tests. We first show that stereotaxic injection of malonate into the internal capsule of rats creates targeted destruction of corticospinal tract fibers. This lesion is associated with long term motor impairments similar to those observed after lacunar stroke in humans. Secondly, I characterized the consequences of stereotaxic injection of malonate into the primary motor cortex of marmoset monkeys. This model was developed in order to reproduce the effects of middle cerebral artery stroke in Humans. Indeed, the blood supply of motor territories strongly depends on this vessel, which is often occluded in ischemic stroke. We show that this approach causes a focal lesion of predictable size and location. Secondary lesions together with astrocyte and microglial infiltration were observed in white matter tracts distant to the lesion site, and likely occur after degeneration of cortico-sub-cortical motor loop axons. Importantly, the lesion was associated with long-lasting loss of dexterity and grip strength of the contralateral forelimb. Stereotaxic injection of malonate therefore reproduces the consequences of ischemic stroke and should allow the investigation of innovative therapies. Stem cell therapy may hold promise for tissue regeneration in the central nervous system (CNS). Co-transplantation of stem cells with biomaterials is currently investigated to enhance the survival and maturation of transplanted cells within the lesion site. Biomaterials can help to create a microenvironment permissive to cell integration within host tissue. An approach combining intracerebral engraftment of semi-rigid micro patterned biomaterials with human neural stem cells (to form a "neuro-implant") improved the recovery of grip strength in stroked rats. [...]
Scheiner, Mark A. "A T.E.M. investigation of endothelial cell junctions in marmoset incisor periodontal ligament following orthodontic extrusion and retention /." Title page, table of contents and summary only, 1996. http://web4.library.adelaide.edu.au/theses/09DM/09dms359.pdf.
Full textTovee, Martin James. "The polymorphism of the middle- to long-wave cone pigments in the common marmoset (Callithrix jacchus jacchus)." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335819.
Full textCox, Charles John. "Persistent EBV infection in the common marmoset : the effect of immunization with envelope glyco protein gp 340." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266318.
Full textAlmond, Rosamunde Elinor Anne. "An investigation into the hormonal and behavioural mechanisms of parental care in the common marmoset (Callithrix jacchus)." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.595482.
Full textBanerji, Tara. "The pharmacological manipulation of L-DOPA-induced dyskinesia in the MPTP-treated marmoset model of Parkinson's disease." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271728.
Full textMaratos, Eleni Chryssa. "Behavioural and biochemical investigations into dyskinesia by levodopa or dopamine agonists in the MPTP-treated common marmoset." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271323.
Full textRahman, Sufia Saburan. "Differential contributions of subregions of the dorsal anterior cingulate cortex to negative emotion in the common marmoset." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/277913.
Full textForster, Felicity. "Exploration in the rat and the marmoset : relationships between learning and object novelty in an open field /." Title page, contents and summary only, 1992. http://web4.library.adelaide.edu.au/theses/09PH/09phf732.pdf.
Full textIrrgang, Jana. "Vergleichende immunhistochemische Untersuchung des Thymusgewebes von Mensch und Marmoset (Callithrix jacchus) unter Verwendung Thymusepithel-spezifischer Antikörper aus Hybridomzelllinien." [S.l.] : [s.n.], 2005. http://www.diss.fu-berlin.de/2005/104/index.html.
Full textCrowe, Paul Richard. "The marmoset periodontal ligament : a T.E.M. morphometric analysis following incisor crown fracture, root canal therapy and orthodontic extrusion /." Title page, contents and summary only, 1989. http://web4.library.adelaide.edu.au/theses/09DM/09dmc953.pdf.
Full textSpine title: A T.E.M. investigation of extrusion and R.C.T. on the marmoset periodontal ligament. Typescript (Photocopy). Includes bibliographical references (leaves 163-191).
Mitchell, Roderick T. "Germ cell development in the human and marmoset fetal testis and the origins of testicular germ cell tumours." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4818.
Full textKönig, Jessica [Verfasser]. "Das endokrine Pankreas des Weißbüschelaffen (Callithrix jacchus) : morphologische und flowzytometrische Untersuchungen unter Berücksichtigung des Wasting-Marmoset-Syndroms / Jessica König." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2011. http://d-nb.info/1018968482/34.
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