Academic literature on the topic 'MARKERS OF DIAGNOSTIC THINKING'

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Journal articles on the topic "MARKERS OF DIAGNOSTIC THINKING"

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Kornilov, N. N., and A. A. Denisov. "A paradigm of early gonarthrosis: a review of the current diagnostic and treatment options (Part 1)." Terapevticheskii arkhiv 89, no. 12-2 (December 20, 2017): 238–43. http://dx.doi.org/10.17116/terarkh20178912238-243.

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The prevalence of chronic joint diseases, among which osteoarthritis (OA) prevails, continues to grow worldwide. So far, many OA patients starting to get any kind of treatment only at the stage of organ failure, when the progression of the pathological process cannot be considerably delayed. The long-felt need for a change in thinking how to effectively diagnose and treat OA patients at early stage induced to prepare this review. Its first part is devoted to discussion of the limitations of traditional approaches and to analysis of the current diagnostic capabilities, particularly the clinical features of early OA, its morphological characteristics based on the magnetic resonance imaging and arthroscopic criteria, as well as the perspectives of biochemical and genetic markers implementation.
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Margolis, A. A., E. V. Gavrilova, L. S. Kuravsky, E. A. Shepeleva, V. K. Voitov, S. S. Ermakov, and P. N. Dumin. "Measuring Higher-Order Cognitive Skills in Collective Interactions with Computer Game." Cultural-Historical Psychology 17, no. 2 (2021): 90–104. http://dx.doi.org/10.17759/chp.2021170209.

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The present study is focused on testing the computer game system ‘PL-modified’ as a diagnostic tool for measurement of higher-order cognitive skills by middle-school students in individual and collaborative game. The ‘PL-modified’ is a computer system designed as a game which implies a set of concrete parameters specially elaborated for assessment of the cognitive actions of analysis, planning, and reflection — the basic higher-order cognitive functions which determine high achievements in school education according to the Russian theory of developmental education. 189 middle-school students at the age of 11—12 years participated in this study. Two research questions were asked: 1) whether the cognitive actions of analysis, planning, and reflection measured by special markers of the computer game system performance are correlated with each other as a valid indicator for the new constructed diagnostic instrument; 2) which type of the game — individual or collaborative — provides better conditions for manifestation of the above mentioned higher mental actions. Abstract intelligence as an additional anticipated factor for high game performance was also assessed and controlled. It was revealed that participants exhibit the higher level of the cognitive actions of analysis and planning in collaborative game. At the same time the patterns of the interactions between the researched variables as well as distinct parameters of game performance are determined by the concrete level of intelligence which rather varies in different pairs of collaborators. We discuss our results from the position of the further prospects for the application of the ‘Pl-modified’ computer system as a potential instrument of measurement and development of higher-order thinking actions. In terms of the modern educational programs teachers need simple diagnostic tools for measurement of school-children’s thinking development. Traditional ‘pen-and-paper’ techniques become quickly outdated as much as they may not be sufficiently motivationally attractive for children and focus only on the result of the thinking process. In this regard, such diagnostic instrument formed in the format of a computer game and centered on the whole gaming process allows fixing children’s actions and provides important information on the dynamic characteristics of their mental process.
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Hollander, Eric, and Stephanie D. Benzaquen. "Is There a Distinct OCD Spectrum?" CNS Spectrums 1, no. 1 (September 1996): 17–26. http://dx.doi.org/10.1017/s1092852900000651.

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The obsessive-compulsive disorders spectrum concept has grown in recent years because of the common clinical features, such as obsessive thinking and compulsive rituals, biological markers, presumed etiology, and treatment response, that these disorders may share with obsessive-compulsive disorder (OCD). This concept has important implications in regard to diagnosis, nosology, neurobiology, and treatment of a wide group of diverse disorders affecting up to 10% of the population. New insights in central nervous system (CNS) mechanisms that drive the repetitive behaviors of the obsessive-compulsive spectrum disorders have heightened interest in the spectrum in researchers, clinicians, and those involved in drug development.An important approach in neuropsychiatry centers on employing a dimensional classification of psychopathology. Psychiatric phenomena often fall on a continuum. A dimensional approach allows for the classification of patients who fall at the border of classical entities or who are otherwise atypical. Diagnostic categories are considered along a spectrum if there is considerable overlap in symptoms and in etiology, as demonstrated by familial linkage biological markers, and pharmacological dissection. Categorical and dimensional approaches to the OCD spectrum could have significant implications for diagnosis, nosology, neurobiology, and treatment of a wide group of disorders affecting a sizable percentage of the population.Recent interest has focused on spectrums in movement disorders, affective disorders, schizophrenia, epileptic and impulsive disorders, and obsessive-compulsive disorders (which we will examine here); in addition, there has been interest in the overlap between these spectrums. Viewing disorders in terms of overlapping spectrums provides researchers and clinicians a framework with which to better understand and treat these disorders.
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Bochelyuk, Vitalii, and Nikita Panov. "Psycholinguistic Problem Field of Studies of the Social Online Networks Discourse." PSYCHOLINGUISTICS 24, no. 1 (October 3, 2018): 79–96. http://dx.doi.org/10.31470/2309-1797-2018-24-1-79-96.

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The research paper deals with theoretical and applied analysis of communication problems in social online networks. It is shown that due to the specifics of the communication channel a virtual community with unique linguistic, cultural and psychological properties are formed (in this case described the change in the landscape of using Internet resources which arose as a result of deployment of the socio-political crisis in Ukraine). The phenomenon of fragmentary brikolage thinking is described, which arises as a result of influence of the hypertext structure and information load of the Internet environment. The nature of network communication gives grounds to speak about the formation of a special form of speech - oral in terms of essence and printed in terms of realization. The personality is presented in the online discourse in a reduced form: as a set of text and visual messages produced by it. Typical forms of communicative activity in the network environment that have a diagnostic and prognostic value are described. The topical prospects of psycholinguistic studies of the discourse of social online networks are identified: the problem of perception and interpretation of text messages; the problem of the relationship between the technological capabilities of the communication channel and the forms of user communicative behavior: the problem of self-presentation and design of effective communications; the problem of adequate “reading” of the linguistic personality being the partner in communication, recognition of markers of certain psychological disorders; the problem of manipulative and mobilizing influence, the need to develop critical thinking skills regarding perceived information, its falsifications and distortions; the problem of influence of online communication on a particular person, his/her outlook and behavior, as well as on society as a whole; the importance of information technology in the ontogenesis of speech. The methodological problem of developing and improving tools for evaluating human behavior on the Internet is presented through the analysis of texts.
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Rodrik, Dani. "Goodbye Washington Consensus, hello Washington confusion?: A review of the World Bank's 'Economic growth in the 1990s: Learning from a decade of reform'." Panoeconomicus 55, no. 2 (2008): 135–56. http://dx.doi.org/10.2298/pan0802135r.

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Proponents and critics alike agree that the policies spawned by the Washington Consensus have not produced the desired results. The debate now is not over whether the Washington Consensus is dead or alive, but over what will replace it. An important marker in this intellectual terrain is the World Bank's Economic Growth in the 1990s- Learning from a Decade of Reform (2005).With its emphasis on humility, policy diversity, selective and modest reforms, and experimentation, this is a rather extraordinary document demonstrating the extent to which the thinking of the development policy community has been transformed over the years. But there are other competing perspectives as well. One (trumpeted elsewhere in Washington) puts faith on extensive institutional reform, and another (exemplified by the U.N. Millennium Report) puts faith on foreign aid. Sorting intelligently among these diverse perspectives requires an explicitly diagnostic approach that recognizes that the binding constraints on growth differ from setting to setting. .
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Rodrik, Dani. "Goodbye Washington Consensus, Hello Washington Confusion? A Review of the World Bank's Economic Growth in the 1990s: Learning from a Decade of Reform." Journal of Economic Literature 44, no. 4 (November 1, 2006): 973–87. http://dx.doi.org/10.1257/jel.44.4.973.

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Proponents and critics alike agree that the policies spawned by the Washington Consensus have not produced the desired results. The debate now is not over whether the Washington Consensus is dead or alive, but over what will replace it. An important marker in this intellectual terrain is the World Bank's Economic Growth in the 1990s: Learning from a Decade of Reform (2005). With its emphasis on humility, policy diversity, selective and modest reforms, and experimentation, this is a rather extraordinary document demonstrating the extent to which the thinking of the development policy community has been transformed over the years. But there are other competing perspectives as well. One (trumpeted elsewhere in Washington) puts faith on extensive institutional reform, and another (exemplified by the U.N. Millennium Report) puts faith on foreign aid. Sorting intelligently among these diverse perspectives requires an explicitly diagnostic approach that recognizes that the binding constraints on growth differ from setting to setting.
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Okasha, A., Z. Bishry, A. H. Khalil, T. A. Darwish, A. Seif El Dawla, and A. Shohdy. "Panic Disorder." British Journal of Psychiatry 164, no. 6 (June 1994): 818–25. http://dx.doi.org/10.1192/bjp.164.6.818.

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We compared three groups of patients with panic disorder, generalised anxiety disorder and major depressive episode with a control group. Methods of comparison included a clinical profile of the patients, assessed by the Arabic version of the Present State Examination (PSE), a psychological battery of tests measuring personality traits and depressive and anxiety states, and the dexamethasone suppression test (DST) as a biological marker. Our data showed that psychological assessment and DST did not significantly differentiate between the three disorders. Despite a symptom overlap between the disorders, however, some symptoms were associated significantly more often with one disorder than another. Patients with panic disorder differed from patients with major depressive episode in showing more situational, avoidance and free floating anxiety, and more anxious foreboding. They showed less self-negligence, ideas of guilt, early awakening and social withdrawal. Compared with patients with generalised anxiety disorder, patients with panic disorder showed more loss of interest and muscle tension and less anxious foreboding, restlessness, inefficient thinking, social withdrawal and delayed sleep. Our conclusion is that the clinical course and the symptom profile of panic disorder justifies its existence as an independent diagnostic category.
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Zavatskyi, V. Yu, and O. O. Blyskun. "SOCIO-PSYCHOLOGICAL SPECIFICS OF YOUNG PEOPLE’S ANTICIPATION AND THEIR WELL-BEING IN THE CONDITIONS OF LIFE CHANGES: ONTO- AND SOCIO-GENESIS." Ukrainian Psychological Journal, no. 2 (14) (2020): 85–99. http://dx.doi.org/10.17721/upj.2020.2(14).4.

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The article identifies diagnostic markers and performance-specific features of young people’s anticipation depending on their age and gender. The social and psychological analysis of their life strategies and anticipation orientations in the conditions of changes was carried out. The sample was differentiated according to the indicators of the leading anticipation constructs and predictors under life changes. The sociopsychological nature of young people’s social well-being was substantiated: the phenomenon of social well-being, its components, indicators, factors of formation were described; the empirical research project on young people’s social well-being was developed and the research was implemented; and correlations between social well-being and anticipation were determined; the referents determining young people’s social well-being were revealed. Mutual relations between an individual’s social well-being and anticipation are supported by patterns that depend on his/her age, gender, general anticipation capacity and individual characteristics (spatial, temporal, personal-situational). In addition, anticipation is developed actively stepby-step. In particular, in adolescence, the ability to anticipate is improved due to qualitative improvement of thinking, as an indirect and generalized reflection of reality; intensive development of those mental qualities that are specific to anticipation, such as: seeing of prospects, taking into account the probabilistic future, proving of made forecast. At the early adulthood, there is the mutual influence of the general anticipation ability and health, reflection during anticipation improves considerable. Anticipation at the middle adulthood is often associated with well-being, which is a sign of psychological health (emotional stability, low anxiety and impulsivity, etc.). In addition, there is a strong link between anticipation and positive well-being at the middle adulthood. Gender differences were revealed for correlations determined between well-being and different anticipatory abilities. Significant correlations between well-being and different anticipatory abilities revealed for women were more numerous and stronger than that of men. The mutual relations among young people’s anticipatory abilities at different levels (personalsituational, spatial and chrono-rhythmic) and the the components of their well-being were determined.
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Elstein, Arthur S. "Thinking about diagnostic thinking: a 30-year perspective." Advances in Health Sciences Education 14, S1 (August 11, 2009): 7–18. http://dx.doi.org/10.1007/s10459-009-9184-0.

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Doig, L., R. Griffiths, and J. Robertson. "BUILDING CULTURAL CAPITAL IN THE AUSTRALIAN OIL AND GAS INDUSTRY." APPEA Journal 44, no. 1 (2004): 771. http://dx.doi.org/10.1071/aj03041.

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One of the key barriers to significant cost-savings and harnessing opportunities for growth in the Australian oil and gas industry is lack of trust, openness and misalignment between companies, among teams and among individuals.In research undertaken for APPEA’s Australian Competitive Energy (ACE) initiative over the last three years, one of the top three barriers to growth continually cited by senior and middle level managers has been culture and behaviours. Examples include misalignment between operators and contractors, management and the workforce, joint venture partners, industry and government, and the industry and the community.In the next five years, the Australian oil and gas industry is facing a skills shortage, technically challenging projects with less people and adaptive challenges. Adaptive challenges (Heifetz and Laurie, 2000) are ones where the:problems and solutions are unclear;the solution does not work through command and control;requires a new way of thinking and acting; andrequires the entire organisation to be engaged.Examples of adaptive challenges for our industry are:finding new gas markets;exploration in sensitive areas;high rig mobilisation costs for a small market; andretaining a skilled workforce.These challenges require companies to find new ways of:Attracting and keeping talented people;Increasing profits and shareholder value; andIncreasing creativity and productivity.Adaptive challenges can be achieved by building cultural capital.This paper outlines:Research and feedback from Australian Operations Managers, Supply Managers, Project Managers and Drilling Managers about the need for improving the culture and behaviours;The business case for why building a high performance culture is considered the competitive advantage of the 21st century;How to measure culture including the diagnostic tool used for the CEO workshop;Results from the diagnostic of the CEO group and implications;andHow to move forward individually, as companies and as an industry.The purpose of this paper is to foster debate and discussion about developing a high performing culture in the Australian oil and gas industry. We intuitively know that valuing our people makes good business sense. To transform the industry’s culture, it is not the organisations that transform, but the people. Shifting the culture requires leadership, courage and commitment from the industry’s senior management.
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Dissertations / Theses on the topic "MARKERS OF DIAGNOSTIC THINKING"

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Цыплакова, Е. С., and E. S. Tsyplakova. "Исследование профессионального мышления студентов-психологов : магистерская диссертация." Master's thesis, б. и, 2021. http://hdl.handle.net/10995/100001.

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Объектом исследования является профессиональное мышление студентов-психологов. Предметом исследования являлись предикторы развития диагностического мышления. Магистерская диссертация состоит из введения, трех глав, заключения, списка литературы (61 источник) и приложения, включающего в себя результаты методик (в баллах) и содержание теста. Объем магистерской диссертации 94 страниц, на которых размещены 1 рисунок и 5 таблиц. Во введении раскрывается актуальность проблемы исследования, разработанность проблематики, ставятся цель и задачи исследования, определяются объект и предмет исследования, формулируются гипотезы, указываются методы и эмпирическая база, а также этапы проведения исследования, теоретическая и практическая значимость работы. Первая глава включает в себя обзор иностранной и отечественной литературы по теме исследования профессионального мышления психологов и студентов-психологов. Представлены разделы, раскрывающие структуру феномена, его параметры и механизмы. Выводы по первой главе представляют собой итоги по изучению теоретического материала. Вторая глава посвящена практической деятельности психолога. В ней выделяется психодиагностика, как главная практическая деятельность психолога. Рассматривается структура, механизмы и особенности написания диагностического заключения психологом. Определяются психолингвистические параметры для оценки итоговых заключений студентов. Раскрывать особенности интеллектуальных и личностных характеристик письменной речи психолога. Выводы по главе 2 включают в себя основные результаты. Третья глава посвящена эмпирической части исследования и включает в себя: описание организации и методов проведенного исследования и результатов, полученных по всем использованным методикам (16-факторный личностный опросник Р.Б.Кеттела, опросник «Уровень субъективного контроля» и профориентационный тест на определение склонности и интереса к профессии психолог). Также представлен корреляционный и сравнительный анализ результатов исследования. В заключении в обобщенном виде изложены результаты теоретической и эмпирической частей работы, а также выводы по выдвинутым гипотезам, обоснована практическая значимость исследования и описаны возможные перспективы дальнейшей разработки данной проблематики.
The object of the study is the professional thinking of psychology students. The subject of the study was predictors of the development of diagnostic thinking. The master's thesis consists of an introduction, three chapters, a conclusion, a list of references (61 sources) and an appendix that includes the results of the methods (in points) and the content of the test. The volume of the master's thesis is 94 pages, which contain 1 figure and 5 tables. The introduction reveals the relevance of the research problem, the development of the problem, sets the goal and objectives of the research, defines the object and subject of the research, formulates hypotheses, specifies methods and empirical base, as well as the stages of the research, the theoretical and practical significance of the work. The first chapter includes a review of foreign and domestic literature on the topic of research of professional thinking of psychologists and psychology students. The sections that reveal the structure of the phenomenon, its parameters and mechanisms are presented. The conclusions of the first chapter are the results of the study of the theoretical material. The second chapter is devoted to the practical work of a psychologist. It highlights psychodiagnostics as the main practical activity of a psychologist. The structure, mechanisms and features of writing a diagnostic conclusion by a psychologist are considered. Psycholinguistic parameters are determined for evaluating the final conclusions of students. To reveal the features of the intellectual and personal characteristics of the written speech of the psychologist. The conclusions of chapter 2 include the main results. The third chapter is devoted to the empirical part of the study and includes: a description of the organization and methods of the study and the results obtained by all the methods used (the 16-factor personal questionnaire of R. B. Kettel, the questionnaire "The level of subjective control" and the career guidance test to determine the propensity and interest in the profession of psychologist). A correlation and comparative analysis of the results of the study is also presented. In conclusion, the results of the theoretical and empirical parts of the work, as well as conclusions on the hypotheses put forward, are summarized, the practical significance of the study is justified and possible prospects for further development of this problem are described.
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Satterthwaite, Gemma. "Discovery of diagnostic markers for atherosclerosis." Thesis, University of Sheffield, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274961.

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Clark, Rachael Louise. "Diagnostic markers of infection, in chronic wounds." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55725/.

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A complication associated with wound healing is wound infection. The diagnosis of infection in chronic wounds can be a difficult clinical decision. Signs and symptoms used to diagnose infection can often be masked by factors relating to the host, chronic inflammation and the tissue damage, associated with chronic wounds. This Study aimed to determine whether there is a measurable biochemical host response that could serve as potential biomarkers of chronic wound infection, providing an alternative diagnostic tool to aid the Clinician. An in vitro model further investigated the expression of markers from neutrophils, in response to bacterial supernatant from Pseudomonas aeruginosa and Staphylococcus aureus commonly associated with chronic wounds and their infections. Chronic venous leg ulcer and diabetic foot ulcer wound fluids were collected, wound microflora assessed, and a variety of host factors, including serine proteases, matrix metalloproteinase, their inhibitors and cytokines/growth factors, IL-ip, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, 11-12 p40, IL-12p70 and IL-13, angiogenin, IFN-y, TGF-pi, VEGF, TNF-a, TNF-r2, ICAM-1 and IP-10, analysed. No significant differences (p>0.1) in the activities/levels of host factors were observed between non-infected and infected wounds, based on clinical diagnosis. Significant differences (p<0.05) in a variety of these host factors were observed in these ulcer types, upon defining infection by wound microbial bioburden, the number of genera or bacterial species. Of these factors, cytokines were found to distinguish on two of the three defining parameters. Specifically, a number of cytokines were found to be significantly elevated in venous leg ulcer wounds, IL-lp, TNF-a, TNFr2 and ICAM-1, with an additional set of cytokines, IL-2, IL-5, IL-12p40, IL-12p70, IFN-y and TGF-P,, significantly decreased within diabetic foot ulcer wounds. in vitro, neutrophils were treated with Pseudomonas aeruginosa or Staphylococcus aureus 'acellular' supernatants, at mid-log or stationary growth phases, for 4 and 24h. Significant increases (p<0.05) in the levels of proteases and cytokines were observed from neutrophils, treated with both mid-log and stationary phase supernatants, from both species. These increases were both neutrophil donor- and growth phase-dependent. A larger cytokine response was induced from neutrophils stimulated with stationary phase, compared with mid-log phase supernatants. Combined with the increased expression of virulence factors, including bacterial enzymes, this Study suggests that bacterial growth is an important feature of chronic wound infection.
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Andreasen, Niels. "Search for reliable diagnostic markers for Alzheimer's disease /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4039-8/.

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Essack, Magbubah. "Transcription Regulation and Candidate Diagnostic Markers of Esophageal Cancer." Thesis, University of the Western Cape, 2009. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_5306_1267148426.

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This thesis reports on the development of a novel comprehensive database (Dragon Database of Genes Implicated in Esophageal Cancer, DDEC) as an integrated knowledge database aimed at representing a gateway to esophageal cancer related data. More importantly, it illustrates how the biocurated genes in the database may represent a reliable starting point for divulging transcriptional regulation, diagnostic markers and the biology related to esophageal cancer.

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Al-Khalili, Faris. "Coronary heart disease in women : diagnostic and prognostic markers /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4092-4/.

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Dreesman, Alexandra. "Development and evaluation of new diagnostic markers of tuberculosis in children." Doctoral thesis, Universite Libre de Bruxelles, 2020. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/312223.

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Tuberculosis in the number one infectious cause of death worldwide, but remains underappreciated as a cause of mortality in children and difficult to diagnose. Diagnostic difficulties of TB in children are a consequence of the non-specific clinical presentation, the different spectrum of disease in children and the paucibacillary nature of disease making microbiological confirmation challenging in many cases. Moreover, existing immunodiagnostic tests have important limitations, especially with regard to childhood TB: they lack sensitivity to rule out TB, and are unable to offer discrimination between contained infection and active stages of disease. Their limitations are emphasized in the youngest children that are at greatest risk of developing severe disseminated forms of TB. For that reason we developed, at the Laboratory of Vaccinology and Mucosal Immunity (LoVMI), several non-sputum based tests, that offer excellent diagnostic accuracy compared to commercialy available tests, for all forms of TB in children, in an early stage of infection. This research also provided insight in TB pathogenesis. The main results are summarized in a table (chapter General Discussion) and two algoritms (chapter Conclusions and Perspectives).
Doctorat en Sciences médicales (Médecine)
info:eu-repo/semantics/nonPublished
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Nouzová, Eva. "Eye movements as diagnostic trait markers for adult major depressive disorder." Thesis, University of Aberdeen, 2016. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=230162.

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Diagnosis of Major Depressive Disorder (MDD) is currently symptom-based and no externally validated tests are available for routine use to confirm clinical diagnoses. Eye movement abnormalities in schizophrenia (SCZ) and bipolar disorder (BPAD) have been consistently reported and their potential as a biological trait marker highlighted. Only a limited amount of research has been conducted in MDD. Eye movement performance of MDD patients (n = 99; F:M = 55:44; Mdn age = 48) was investigated using picture free-viewing, smooth pursuit and fixation stability tasks and recorded using a non-invasive EyeLink1000 infra-red eye tracker. Performance was compared with identical measures from SCZ, BPAD, Primary Care depression (DEP) and control participants. Analysis was conducted using analyses of variance and machine learning using Probabilistic Neural Networks (PNN). We discovered a unique MDD specific eye movement phenotype, which differentiated patients with MDD from other diagnostic groups with remarkable accuracy. MDDs generated a markedly poor smooth pursuit performance, characterised by small signal-to-noise ratio, small tracking gain and large positional error. Patients also exhibited a slow average saccade velocity during free-viewing and pursuit, and poor fixation maintenance on a centralised target. A PNN classifier delineated MDD from controls with exceptional statistical sensitivity (100%) and specificity (99%), independent of state or demographics. MDD was delineated from SCZ and BPAD in all models with above 89% sensitivity and 95% specificity. MDD and DEP patients were delineated with remarkable statistical sensitivity (90%) and specificity (98%). This emerging evidence suggests possible subtypes consistent with clinical features. Testretest reliability was high for a majority of performance measures; however some measures were less robust. Brief neuropsychology assessment advocated the role of frontal lobes in oculomotor behaviour. This preliminary evidence argues for a specific MDD oculomotor dysfunction and represents potential for a diagnostically applicable biological trait marker.
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Zheng, Yingye. "Semiparametric methods for longitudinal diagnostic accuracy /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/9580.

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Arko-Mensah, John. "Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance." Doctoral thesis, Stockholm University, Wenner-Gren Institute for Experimental Biology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8208.

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IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages in vitro. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. In terms of mechanisms, neither TNF nor nitric oxide (NO) production was significantly affected, and the refractoriness induced could be reversed with increasing amounts of IFN-γ In the second study, we aimed to identify immunological markers of diagnostic importance in both the respiratory tract and serum during pulmonary mycobacterial infection in mice. We found that increased levels of immunological markers in the respiratory tract, but not serum, correlated better with active mycobacterial infection in the lungs, suggesting that the immune response in the respiratory tract is more reflective of the infection status and pathology than the systemic response. Finally, we investigated the level and nature of immune responses to pulmonary mycobacterial infection in BALB/c and C57BL/6 mice, two mouse strains known to exhibit different susceptibilities to infection with several intracellular pathogens, including mycobacteria. We showed that increased susceptibility of BALB/c mice to early mycobacterial infection was associated with reduced Th1 immune responses, and increased sTNFR secretion in the lung. Moreover, BALB/c mice recruited fewer monocytes/macrophages to the lung, and although IFN-γ stimulation of infected bone marrow derived macrophages in both mouse strains resulted in induction of antimycobacterial activity, BALB/c mice had a reduced capacity to kill ingested bacteria. The work presented in this thesis provide further insight into the mechanisms involved in the host-pathogen interaction; from persistence, to the immunological processes induced by the pathogen, to susceptibility of the host to infection.

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Books on the topic "MARKERS OF DIAGNOSTIC THINKING"

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Casadio, Valentina, and Samanta Salvi, eds. Cell-free DNA as Diagnostic Markers. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-8973-7.

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Tan, Eng M. Antibody markers in systemic autoimmunity. Summit, N.J: CIBA-GEIGY Corp., 1992.

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F, Leonard R. C., ed. Serological tumour markers: An introduction. Edinburgh: Churchill Livingstone, 1993.

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Diagnostic assays for colon cancer. Boca Raton: CRC Press, 1991.

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Tumor markers: Clinical and laboratory studies. New York: A.R. Liss, 1985.

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International Conference on Human Tumor Markers (2nd 1984 Vienna, Austria). Tumor markers in cancer control. Edited by Niebergs Herbert, Holzner J. Heinrich, and Valli Victor E. New York: Liss, 1985.

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Alzheimer's disease: Targets for new clinical diagnostic and therapeutic strategies. Boca Raton, FL: CRC Press/Taylor & Francis, 2012.

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Bennett, Jacey J. Attemps to identify species-diagnostic RAPD markers useful in differentiation rye from wheat. Sudbury, Ont: Laurentian University, 2004.

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Lange, Paul H. Tumor markers in the diagnosis and management of urologic cancer. Bellaire, Tex: American Urological Assoc., 1992.

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Biologic markers in pulmonary toxicology. Washington, D.C: National Academy Press, 1989.

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Book chapters on the topic "MARKERS OF DIAGNOSTIC THINKING"

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Rea, William S., Irl L. Extein, and Mark S. Gold. "Biological Markers." In Issues in Diagnostic Research, 161–78. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1265-9_6.

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Rosner, Gary L., Purushottam W. Laud, and Wesley O. Johnson. "Diagnostic Tests." In Bayesian Thinking in Biostatistics, 481–508. First edition. | Boca Raton: CRC Press, 2021.: Chapman and Hall/CRC, 2021. http://dx.doi.org/10.1201/9781439800102-15.

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Witte, Torsten. "Diagnostic Markers of Sjögren’s Syndrome." In Research Projects in Dry Eye Syndrome, 123–28. Basel: KARGER, 2010. http://dx.doi.org/10.1159/000315025.

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Lennon, Anne Marie, and Michael Goggins. "Diagnostic and Therapeutic Response Markers." In Pancreatic Cancer, 675–701. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-0-387-77498-5_28.

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Labugger, Ralf, D. Kent Arrell, and Jennifer E. Van Eyk. "Cardiac Troponins: Exploiting the Diagnostic Potential of Disease-Induced Protein Modifications." In Cardiac Markers, 125–38. Totowa, NJ: Humana Press, 2003. http://dx.doi.org/10.1007/978-1-59259-385-9_7.

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Multigner, L., A. De Caro, G. Montalto, M. Provansal-Cheylan, and H. Sarles. "Biochemical Markers of Chronic Pancreatitis." In Diagnostic Procedures in Pancreatic Disease, 208–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71128-2_31.

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Adams, Jesse E. "The Use of Biomarkers to Provide Diagnostic and Prognostic Information Following Cardiac Surgery." In Cardiac Markers, 111–21. Totowa, NJ: Humana Press, 2003. http://dx.doi.org/10.1007/978-1-59259-385-9_6.

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Dey, Pranab. "Markers for Immunophenotyping in Flow Cytometry." In Diagnostic Flow Cytometry in Cytology, 97–107. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2655-5_9.

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Davies, P. "Potential Diagnostic Markers for Alzheimer’s Disease." In Biological Markers of Alzheimer’s Disease, 17–22. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-46690-8_2.

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Howitt, C. A., K. R. Gale, and A. Juhász,. "Chapter 11 Diagnostic Markers for Quality." In Gliadin and Glutenin: The Unique Balance of Wheat Quality, 333–61. 3340 Pilot Knob Road, St. Paul, Minnesota 55121, U.S.A.: AACC International, Inc., 2006. http://dx.doi.org/10.1094/9781891127519.015.

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Conference papers on the topic "MARKERS OF DIAGNOSTIC THINKING"

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Mazur, Olena, Olga Yablon, Tatiana Savrun, Anastasiia Konoplitska, and Nataliia Chornopyshchuk. "Diagnostic Markers of Prolonged Neonatal Jaundice." In 9th ICCN International Conference on Clinical Neonatology—Selected Abstracts. Thieme Medical Publishers, 2020. http://dx.doi.org/10.1055/s-0040-1716972.

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Sachs-Olsen, C., KC Lodrup Carlsen, P. Mowinckel, CS Devulapalli, M. Pettersen, MC Munthe-Kaas, and KH Carlsen. "Diagnostic Value of Inflammation Markers in Childhood Asthma and Allergy." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1378.

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Zolubak, Magda, Mariusz Pelc, Dzhulietta Siui, Krystyna Macek-Kaminska, Joanna Kolanska-Pluska, Stepan Ozana, Barbara Grochowicz, and Aleksandra Kawala-Sterniuk. "Application of low frequency wave markers for diagnostic tests and neurofeedback therapy." In 2019 Progress in Applied Electrical Engineering (PAEE). IEEE, 2019. http://dx.doi.org/10.1109/paee.2019.8788972.

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Meaney, Claire L., Khadijah A. Mitchell, Adriana Zingone, Derek Brown, Wei Tang, Yunkai Yu, Liang Cao, and Brid M. Ryan. "Abstract B60: Inflammatory-based diagnostic markers of lung cancer in African Americans." In Abstracts: Ninth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; September 25-28, 2016; Fort Lauderdale, FL. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7755.disp16-b60.

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Subotnicu, Mirabela, Anca Ivanov, I. Ivanov, Adriana Mocanu, Silvia Dumitras, Ciobanu Antonela, Madalina Schmidt, Cristina Rusu, and Ingrith Miron. "P378 Molecular diagnostic markers for childhood acute leukaemia – a single centre experience." In 8th Europaediatrics Congress jointly held with, The 13th National Congress of Romanian Pediatrics Society, 7–10 June 2017, Palace of Parliament, Romania, Paediatrics building bridges across Europe. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2017. http://dx.doi.org/10.1136/archdischild-2017-313273.466.

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Meaney, Claire L., Khadijah A. Mitchell, Adriana Zingone, Derek Brown, Wei Tang, Yunkai Yu, Liang Cao, Angela S. Wenzlaff, Ann G. Schwartz, and Brid M. Ryan. "Abstract 4658: Inflammatory based diagnostic markers of lung cancer in African Americans." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-4658.

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Lang, Martin, Cathy D. Vocke, Maria J. Merino, Laura S. Schmidt, and Marston W. Linehan. "Abstract LB-107: Mitochondrial DNA mutations are diagnostic markers of renal oncocytomas." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-lb-107.

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Bhatt, H., and A. Bush. "P109 Diagnostic markers for allergic bronchopulmonary aspergillosis in paediatric cystic fibrosis patients." In British Thoracic Society Winter Meeting 2018, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 5 to 7 December 2018, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2018. http://dx.doi.org/10.1136/thorax-2018-212555.267.

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Bec, Julien, Deborah vela, L. Maximilian Buja, Kenneth B. Margulies, and Laura Marcu. "Label-free assessment of biochemical markers of atherosclerotic plaque progression using intravascular fluorescence lifetime." In Diagnostic and Therapeutic Applications of Light in Cardiology 2021, edited by Laura Marcu and Gijs van Soest. SPIE, 2021. http://dx.doi.org/10.1117/12.2579155.

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Korkmaz, Elif Tugce, Deniz Koksal, Funda Aksu, Z. Gunnur Dikmen, Duygu Icen, Emin Maden, Sevgen Önder, Filiz Akbıyık, and Salih Emri. "The diagnostic value of serum tumor markers in newly diagnosed lung cancer patients." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa4217.

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Reports on the topic "MARKERS OF DIAGNOSTIC THINKING"

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Voicehovska, Julija, Mila Vlaskovska, Jana Janovska, Sergejs Babikovs, Vladimirs Voicehovskis, Andrejs Skesters, Alise Silova, et al. Oxidative Stress Markers Diagnostic Value in Metabolic Syndrome Dermal Manifestations: a Prospective Clinical Trial. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, February 2018. http://dx.doi.org/10.7546/crabs.2018.02.15.

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Voicehovska, Julija, Mila Vlaskovska, Jana Janovska, Sergejs Babikovs, Vladimirs Voicehovskis, Andrejs Skesters, Alise Silova, et al. Oxidative Stress Markers Diagnostic Value in Metabolic Syndrome Dermal Manifestations: a Prospective Clinical Trial. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, February 2018. http://dx.doi.org/10.7546/grabs2018.2.15.

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The Centre for Attention Learning and Memory (CALM) Approach to Neurodevelopmental Research – MRC Cognition and Brain Sciences Unit University Of Cambridge. ACAMH, April 2021. http://dx.doi.org/10.13056/acamh.15509.

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Abstract:
Our thinking around neurodevelopmental disorders is undergoing a period of rapid change. The traditional approach, endorsed by classification systems such as the Diagnostic Statistical Manual, defines neurodevelopmental disorders such as autism and attention-deficit hyperactivity disorder (ADHD) as distinct categories.
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