Journal articles on the topic 'Maps, World, 1507'
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Unger, Richard W. "Seeing the World Anew: The radical vision of Martin Waldseemuller's 1507 & 1516 world maps." Mariner's Mirror 99, no. 4 (November 2013): 477–78. http://dx.doi.org/10.1080/00253359.2013.848557.
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Peerlings, R. H. J., F. Laurentius, and J. van den Bovenkamp. "New Findings and Discoveries in the 1507/8 Rome Edition of Ptolemy’s Cosmography." Quaerendo 48, no. 2 (June 21, 2018): 139–62. http://dx.doi.org/10.1163/15700690-12341408.
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Abstract In a previous article the watermarks in the text and map pages of the Rome editions of Ptolemy’s Cosmography were described. This article shows how they can be used to reveal hidden knowledge about the development and chronology of the 1507/8 Rome edition of Ptolemy’s Cosmography. It also discusses the discovery of new states of three maps and the appearance of the Ruysch world map in these editions. Atlases in several institutes and libraries in Europe were studied firsthand, whereas information and photographs of atlases in libraries in the United States were collected by e-mail correspondence and internet downloads.
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Schwartz, Seymour I. "Seeing the World Anew: The Radical Vision of Martin Waldseemüller's 1507 & 1516 World Maps. By John W. Hessler and Chet Van Duzer." Imago Mundi 65, no. 2 (June 2013): 304–5. http://dx.doi.org/10.1080/03085694.2013.784625.
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Kontev, Arkadii V. "The First Images of the Ob River on Western European Maps." Vestnik of Saint Petersburg University. History 66, no. 3 (2021): 971–89. http://dx.doi.org/10.21638/11701/spbu02.2021.316.
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Martin Waldseemüller’s maps, published in 1507 and 1513 in Strasbourg, are the first maps to bear the name of the new continent, America. They reveal the discovery of the New World by Spanish and Portuguese navigators. None of the researchers, however, have noticed that the same maps of North Asia (the area of present-day Western Siberia) for the first time show a river flowing into the Arctic Ocean. The peculiarity of Western European cartographic sources at the turn of the 15th–16th centuries lies in the fact that the reflection of the world picture was based on the tradition of the geographer Claudius Ptolemy. The desire to publish the “New Ptolemy” prompted the members of the Vosges Gymnasium, where Waldseemüller worked, to combine traditional knowledge of the world with the latest geographical discoveries. The article analyzes the content of Waldseemüller’s maps, provides a comparative analysis of the maps that formed the basis for the creation of these images, and traces the borrowings of data from the German cartographer by subsequent authors of the 16th century. As a result of careful study of inscriptions and legends, the author concludes that the depiction of areas of North Asia on the maps of the German cartographer dates back to the maps of Henry Martell of 1489–1491. A large map of the world by this author is kept at Yale University, but many of its inscriptions have faded or disappeared. The painstaking work of the American researcher Chet van Duzer, who published a monograph on the map in 2019, gave researchers the opportunity to examine the source carefully. The comparison between this map and an earlier round map of Fra Mauro of 1459 suggested that Martell, in his turn, borrowed the image of the North Asian river from this Venetian monk. Thus, the process of borrowing and clarifying the information about the previously unknown river is traced. At the end of the article, the author proves that European cartographers displayed the latest information about the Ob river, which came from Russia.
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Brotton, Jerry. "John W. Hessler and Chet A. Van Duzer. Seeing the World Anew: The Radical Vision of Martin Waldseemüller’s 1507 and 1516 World Maps. Delray Beach: Levenger Press in association with the Library of Congress, 2012. 112 pp. + 2 maps. $85. ISBN: 978–1–929154–47–0." Renaissance Quarterly 66, no. 2 (2013): 703–4. http://dx.doi.org/10.1086/671664.
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Taborska, Małgorzata. "Złoty Globus Jagielloński ze zbiorów Muzeum Uniwersytetu Jagiellońskiego – niezwykły obiekt z fascynującą historią." Opuscula Musealia 27 (2021): 39–65. http://dx.doi.org/10.4467/20843852.om.20.003.13742.
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The Golden Jagiellonian Globe from the Jagiellonian University Museum Collection – an unusual object with a fascinating history “The Golden Jagiellonian Globe” (early 16th century; in the collection of the Jagiellonian University Museum) is the earliest globe of the Earth in the Polish collections and one of the oldest in the world. The oldest known globe of the Earth was made by Martin Behaim in 1492. The second in order are two globes from the same period: the Hunt-Lenox Globe (c. 1510, now in the New York Public Library) and the Jagiellonian Globe. Despite its name, the Jagiellonian Globe is an astronomical instrument – a mechanical armillary sphere. On the orb hiding the mechanism there is a map of the Earth, dated 1510–1511. This object has been sparsely analysed, especially in the last decades. Those analysis that were performed have until now mainly focused on the depicted map and the typology of particular details, though there are also studies on its operation and provenance. Research performed in the 21st century focused on WWII history of the globe.A preliminary analysis of the sphere and the clock mechanism allows a connection with French products from Blois near Paris. The map of the globe, associated with the Italian centre, presents information on geographical discoveries of the time, based on maps by Martin Waldseemüller and letters by Amerigo Vespucci, published in the edition of Ptolemy’s Geography (Saint-Dié, 1507). The map is a twin to the layout of the lands and seas depicted on Hunt-Lenox’s Globe. It is distinguished by a mysterious continent-island, noted on the Kraków globe as “America Noviter Reperta.” The provenance of the globe is known since the 17th century, when the Kraków professor, Jan Brożek, donated it to the Collegium Maius library of the Jagiellonian University. Its fate during World War II, when it was hidden from the Nazis by docent Jadwiga Schoen, is extraordinary. After the war, the globe found its way to the Jagiellonian University Museum, where it has been exhibited ever since.
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Lewis, Thomas. "Woodruff, A Concise History Of The Modern World - 1500 To The Present." Teaching History: A Journal of Methods 25, no. 1 (April 1, 2000): 38–40. http://dx.doi.org/10.33043/th.25.1.38-40.
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It would be difficult to imagine how anyone could write a better overview of the last five hundred years of world history. William Woodruffs book is filled with relevant facts, appropriate questions, interesting anecdotes, and insightful interpretations. Regrettably, the book contains no illustrations, but there are twenty-five useful maps.
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Sánchez, Antonio. "An Official Image of the World for the Hispanic Monarchy." Nuncius 29, no. 2 (2014): 389–438. http://dx.doi.org/10.1163/18253911-02902002.
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This paper discusses the Padrón Real (Royal Pattern Chart or master sea chart), an official class of maps of the world instituted by the Spanish monarchy and produced by Seville’s Casa de la Contratación (House of Trade) from 1508 onwards, in a political context dominated by the dispute between the two largest expansionist empires in Europe – Portugal and Castile – which was heightened following the signing of the Treaty of Tordesillas in 1494. The Padrón Real became a model for European cartographers and its history sheds light on the development of map-making practices at the Casa in the Crown’s attempt to regulate cosmography for its own political ends. The Padrón Real was unprecedented for its time and, together with the question of how to determine longitude, reflected what were the most important cartographic challenges facing the early modern world: how to represent a three-dimensional body – the globe – on a flat surface and how to provide reliable geographic maps when they were subject to constant revision.
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Massing, Andreas. "Valentim Fernandes' Five Maps and the Early History and Geography of São Tomé." History in Africa 36 (2009): 367–86. http://dx.doi.org/10.1353/hia.2010.0013.
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Maps may be important historical documents, reflecting the situation of a given place at a given time, and comparing several maps from different periods of the same area can inform us of changes in social and human geography. For some distant parts of the world they may be the only sources for a past that provides us with few if any sources. Thus Valentim Fernandes' five maps of São Tomé are a unique source for the slow and gradual growth of the first settlements. The maps are complemented by Fernandes' 1506 description of the island.Valentim Fernandes, a German printer who worked in Lisbon from 1495 to 1513, compiled several works on Africa and published them in 1506. Apparently he sent a copy to his friend Conrad Peutinger in Augsburg, whose book collection came into possession of the Bayerische Staatsbibliothek, where they survive in the Codex Hispanicus 27 (now available online. The compilation contains several texts and a map collection with description of the Atlantic islands. While Fernandes' description of Africa, as the sole copy of Diogo Gomes' account, has received wide attention as an important source for early African history, the five maps of São Tomé inserted at various places in the Codex have hardly received any attention at all.
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Bockelman, Brian. "Maps and Mapmaking Techniques - Mapping an Atlantic World, Circa 1500. By Alida C. Metcalf. Baltimore: John Hopkins University Press, 2020. Pp. 256. $54.95 cloth." Americas 78, no. 3 (June 28, 2021): 507–8. http://dx.doi.org/10.1017/tam.2021.58.
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Baumgärtner, Ingrid. "Alfred Hiatt (Ed.), Cartography between Christian Europe and the Arabic-Islamic World, 1100–1500. Divergent Traditions. (Maps, Spaces, Cultures, Vol. 3.) Leiden, Brill 2021." Historische Zeitschrift 315, no. 3 (December 1, 2022): 774–76. http://dx.doi.org/10.1515/hzhz-2022-1453.
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ILIEȘ, Alexandru, Jan A. WENDT, Oliver DEHOORNE, and Codruț G. BULZ. "Amateur football map (4th league) from Romania generated by the coronavirus (COVID-19) in the pre-pandemic season (2019/2020)." GeoSport for Society 15, no. 2 (December 31, 2021): 122–34. http://dx.doi.org/10.30892/gss.1505-078.
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After the 2nd World War, for the first time after 7 decades, sports in general, and amateur football in particular, are facing a new global challenge generated by the coronavirus (COVID-19) pandemic. Pre-pandemic football season 2019/2020 held on the field only for the first part (690 teams; 781 games), was suspended at the beginning of March, 2020. This situation generated an uncertain 5-month break until the first official games in play-offs (1-9 August, 2020) in wich only 46 teams (6.6%) in total actually participated. In a state of global uncertainty, to the suggestion of RFF, the 42 county football associations were “invited” to identify new solutions in order to “finalize the season”, by declaring, or not, a champion team, another team for the national phase of Romania’s Cup and a county representative for the 3rd league play-off. With the help of statistical information provided by county structures, with the spatial analysis of statistical data reported and analyzed on local and regional level, were analyzed the created situations and, especially, the consequences generated by the pandemic situation upon amateur football in Romania illustrated by maps.
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ILIEȘ, Alexandru, Jan A. WENDT, Oliver DEHOORNE, and Codruț G. BULZ. "Amateur football map (4th league) from Romania generated by the coronavirus (COVID-19) in the pre-pandemic season (2019/2020)." GeoSport for Society 15, no. 2 (December 31, 2021): 122–34. http://dx.doi.org/10.30892/gss.1506-078.
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After the 2nd World War, for the first time after 7 decades, sports in general, and amateur football in particular, are facing a new global challenge generated by the coronavirus (COVID-19) pandemic. Pre-pandemic football season 2019/2020 held on the field only for the first part (690 teams; 781 games), was suspended at the beginning of March, 2020. This situation generated an uncertain 5-month break until the first official games in play-offs (1-9 August, 2020) in wich only 46 teams (6.6%) in total actually participated. In a state of global uncertainty, to the suggestion of RFF, the 42 county football associations were “invited” to identify new solutions in order to “finalize the season”, by declaring, or not, a champion team, another team for the national phase of Romania’s Cup and a county representative for the 3rd league play-off. With the help of statistical information provided by county structures, with the spatial analysis of statistical data reported and analyzed on local and regional level, were analyzed the created situations and, especially, the consequences generated by the pandemic situation upon amateur football in Romania illustrated by maps.
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Brown, James, and Douglass Sullivan-Gonzales. "A "Great Roads" Approach To Reaching Modern World History And Latin American Regional Survey Courses." Teaching History: A Journal of Methods 27, no. 2 (September 1, 2002): 59–73. http://dx.doi.org/10.33043/th.27.2.59-73.
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In January of 2000, the authors of this article made a ten-day field trip along Mexico's Veracruz to Mexico City corridor, with notebooks, detailed maps, and digital camera in hand. This was all in support of their recent experience in teaching history survey courses on their respective campuses. Jim Brown of Samford University has been developing interactive three-dimensional topography models as a basis for his sophomore modem world history course. Doug Sullivan-Gonzalez, Latin American historian at the University of Mississippi, has been fine-tuning his introductory regional history courses in the Croft International Program there. We have both gravitated towards use of a "great roads" approach. Twenty years of discussion between us, including recent visits to each other's campuses and incorporation of some of the other's approaches, led up to this joint field trip. In this article we first outline an innovative "great roads" way of teaching "World History Since 1500" as it has evolved at Samford in recent years. Then at more length we develop the "Veracruz to Mexico City corridor" case study approach to the modem history of Latin America as we both now use it in our survey courses.
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Siang, Chang Yueh. "Southeast Asia. Sarong kebaya: Peranakan fashion in an interconnected world, 1500–1950 By Peter Lee Singapore: Asian Civilisations Museum, 2014. Pp. 352. Maps, Plates, Notes, Bibliography, Index." Journal of Southeast Asian Studies 48, no. 2 (May 3, 2017): 313–15. http://dx.doi.org/10.1017/s0022463417000364.
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Morse, Victoria M. "Cartography between Christian Europe and the Arabic-Islamic World, 1100–1500: Divergent Traditions. Alfred Hiatt, ed. Maps, Spaces, Cultures 3. Leiden: Brill, 2021. xiv + 235 pp. $113." Renaissance Quarterly 76, no. 4 (2023): 1500–1501. http://dx.doi.org/10.1017/rqx.2023.602.
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Lechner, J. "Dutch Humanists' Knowledge of America." Itinerario 16, no. 2 (July 1992): 101–13. http://dx.doi.org/10.1017/s0165115300022154.
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Recent decades have witnessed a growing awareness of the need to study the impact of the New World on the Old, instead of the other way about. Yet surprisingly little is known about the whereabouts of books on America, or of atlasses and maps of this new world, in the libraries of European intellectuals from, say, 1500 until 1700 (the same holds true, incidentally, for texts about Asia). A possible explanation for this state of affairs might be that it is easier, although difficult enough, to compile a reliable bibliography of printed sources on America, as the splendid European Americana amply proves, than to ascertain what books figured in private libraries which are no longer intact. Furthermore, research into the private libraries of the past is still a somewhat modest sector of the province of intellectual history, in spite of the fact that Mario Schiff's brilliant study of the Marqués de Santillana's library dates from 1905 and that Henri-Jean Martin's seminal works have been published since 1958.
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Stajnko, Denis. "Mogućnost povećanja učinkovitosti pripreme tla i sjetve ozimih žita pomoću tehnologije precizne poljoprivrede." Glasnik zaštite bilja 41, no. 5 (October 24, 2018): 20–27. http://dx.doi.org/10.31727/gzb.41.5.3.
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The concept of precision farming is wide, and it is represented with the efficiency achieved with the help of precise RTK (Real Time Kinematic) navigation, digital maps and appropriate software. Different studies around the world reported considerable fuel and time saving during soil tillage and seeding which based on omitting the overlapping and the frequency of turning round at the end of fields. For smaller farms, which commonly use 3 m working machines (cultivator, chisels, disc harrow) up to 15.7% of the time and 8.66 % of the fuel can be saved, while on 6 m machines up to 12.6 % of the time and 8.28% of fuel is saved. The main reason lies in the reduction of overlapping width which in manual driving conditions usually represent about 10 % of nominal working width. The use of precision agriculture technologies allows us to better plan and analyze the working procedures.
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Maddox, G. H. "Maize and Grace: Africa's Encounter with a New World Crop, 1500-2000. By James C. McCann. Cambridge: Harvard University Press, 2005. xiv + 289. Illustrations, maps, notes, index. Cloth $27.95." Environmental History 11, no. 4 (October 1, 2006): 850–53. http://dx.doi.org/10.1093/envhis/11.4.850.
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Uribe, Victor M. "Europe and The Wider World - Saliha Belmessous. Native Claims. Indigenous Law against Empire, 1500-1920. London: Oxford University Press, 2012, 278 pp., 7 maps, 2 drawings. ISBN: 9780199794850 (hbk.). $74." Itinerario 36, no. 3 (December 2012): 138–40. http://dx.doi.org/10.1017/s0165115313000119.
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Gerritsen, Anne. "‘A Place full of Trade’: Placing an Early Modern Chinese Town in Global Cultural History." Cultural History 9, no. 2 (October 2020): 171–94. http://dx.doi.org/10.3366/cult.2020.0220.
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This article focuses on the history of Wuchengzhen 吳 城 鎮, a small town in the inland province of Jiangxi. It explores the history of the town between 1500 and 1850 in terms of both its local significance as an entrepot for trade in grain and tea and its global connections to early modern Europe, by way of the trade in porcelain. The question this paper explores concerns the juxtaposition between, on the one hand, the idea gained from global historians, that during the early modern period, globally traded commodities like tea and porcelain situate a small town like this in a globalized, perhaps even unified or homogenous, world, and on the other hand, the insight gained from cultural historians, that no two people would ever see, or assign meaning to, this small town in the same way. Drawing on this insight, the history of Wuchengzhen is explored on the basis of different textual (administrative records, local gazetteers, merchant manuals) and visual sources (maps and visual depictions of the town), exploring the ways in which the different meanings of the town are constructed in each. The combination of global and cultural history places Wuchengzhen on our map of the early modern world.
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Canbakal, Hülya. "The Ottoman State and Descendants of the Prophet in Anatolia and the Balkans (c. 1500-1700)." Journal of the Economic and Social History of the Orient 52, no. 3 (2009): 542–78. http://dx.doi.org/10.1163/156852009x458241.
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AbstractThroughout the Islamic world those claiming descent from the Prophet Muhammad (T. seyyid/şerif, pl. sadat/eşraf) were (and are) accorded a special status. This article shows that the process of teseyyüd ("seyyidization") not only took place through official awards, but also through appropriation. In the Ottoman Empire registers thus began to be kept of officially recognized sadat. The examination of these, largely un(der)studied, sources argues that the state sometimes employed its capacity to seyyidize for (cultural) political purposes. The article also sheds valuable light on Ottoman policies vis-à-vis tribalism and nomadism. Dans le monde islamique entier un statut spécial était (et est) accordé à tous ceux qui revendiquent descendance du Prophète Mahomet (T. seyyid/şerif, pl. sadat/eşraf). Dans cet article on explique que le processus de tessyyüd ('seyyidisation') se passait non seulement par attribution officielle, mais aussi par appropriation. Dans l'Empire ottoman on a commencé ainsi à tenir des registres de sadat officiellement reconnu. L'examen de ces sources largement sous-étudiées démontre que l'État parfois usait de son autorité de 'seyyediser' pour des fins politiques (culturelles). Cet article jette en même temps une lumière de grande valeur sur la politique ottomane quant au tribalisme et au nomadisme.
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Bingen, James. "History - James C. McCann. Maize and Grace: Africa's Encounter with a New World Crop, 1500–2000. Cambridge: Harvard University Press, 2005. xiii + 288 pp. Photographs. Maps. Illustrations. Appendixes. Bibliography. Index. $27.95. Cloth." African Studies Review 49, no. 1 (April 2006): 156–58. http://dx.doi.org/10.1353/arw.2006.0057.
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Hu, Hongyu, Ming Cheng, Fei Gao, Yuhuan Sheng, and Rencheng Zheng. "Driver’s Preview Modeling Based on Visual Characteristics through Actual Vehicle Tests." Sensors 20, no. 21 (October 31, 2020): 6237. http://dx.doi.org/10.3390/s20216237.
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This paper proposes a method for obtaining driver’s fixation points and establishing a preview model based on actual vehicle tests. Firstly, eight drivers were recruited to carry out the actual vehicle test on the actual straight and curved roads. The curvature radii of test curved roads were selected to be 200, 800, and 1500 m. Subjects were required to drive at a speed of 50, 70 and 90 km/h, respectively. During the driving process, eye movement data of drivers were collected using a head-mounted eye tracker, and road front scene images and vehicle statuses were collected simultaneously. An image-world coordinate mapping model of the visual information of drivers was constructed by performing an image distortion correction and matching the images from the driving recorder. Then, fixation point data for drivers were accordingly obtained using the Identification-Deviation Threshold (I-DT) algorithm. In addition, the Jarque–Bera test was used to verify the normal distribution characteristics of these data and to fit the distribution parameters of the normal function. Furthermore, the preview points were extracted accordingly and projected into the world coordinate. At last, the preview data obtained under these conditions are fit to build general preview time probability density maps for different driving speeds and road curvatures. This study extracts the preview characteristics of drivers through actual vehicle tests, which provides a visual behavior reference for the humanized vehicle control of an intelligent vehicle.
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Wolcott, Susan. "How India Clothed the World: The World of South Asian Textiles, 1500–1850. Edited byGiorgio Riello and Tirthankar Roy. Leiden: Brill, 2009. xxxiv + 489 pp. Illustrations, photographs, maps, glossary, figures, tables, bibliography, notes, index. Cloth, $188.00. ISBN: 978-90-04-17653-9." Business History Review 86, no. 3 (2012): 589–92. http://dx.doi.org/10.1017/s0007680512001092.
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BORKENT, ART. "The Frog-Biting Midges of the World (Corethrellidae: Diptera)." Zootaxa 1804, no. 1 (June 16, 2008): 1. http://dx.doi.org/10.11646/zootaxa.1804.1.1.
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This worldwide biosystematic study of Corethrellidae, with its single genus Corethrella Coquillett, provides a complete compilation of all that is known for the group, both taxonomically and bionomically. Descriptions of each species are based primarily on the adults, summarize all bionomic information, and provide a map showing its distribution. Keys to the species of each region are provided. A total of 97 extant species is recognized, with 52 of these being new. Seven fossil species are described with two of these being new to science. All species, including 13 new synonyms, are cataloged in a table for easy reference. Seven extant species are of uncertain status because of damaged or missing types. Lectotypes and, depending on the species, some paralectotypes, are designated for the following species: C. inepta (Annandale), C. pallitarsis Edwards, C. picticollis Edwards, C. ananacola Dyar, C. calathicola Edwards, and C. brakeleyi (Coquillett). A cladistic analysis interprets most extant and fossil species (some are not interpretable at the present time) and provides the basis for zoogeographic and bionomic interpretation. Worldwide, Corethrella species are found between 50°N and 50°S but most are found between 30°N and 30°S and below 1500 meters in elevation. Because female adults are attracted to the call of male frogs and feed on their blood, species are restricted to areas where there are frogs. Phylogenetic patterns suggest Gondwanan connections for earlier lineages within the genus. At least one lineage has dispersed from the New World to southeast Asia and some species are located on volcanic islands in the Caribbean, indicating further instances of dispersal. It is certain that many more species are yet to be discovered. Phylogenetic patterns indicate that the immatures of Corethrella species have repeatedly moved between ground-dwelling habitats and phytotelmata, with the plesiotypic habitat likely being ground-dwelling. Some lineages have diversified within phytotelmata. Fossil, cladistic and morphological evidence indicates that Corethrella females have been feeding on calling frogs since at least the Early Cretaceous. Females likely hear their frog hosts using the Johnston’s Organ. There is some evidence of host specificity as well as selection of particular biting sites for some species of Corethrella. The females of at least some species of Corethrella transmit Trypanosoma Gruby between calling frogs and this association is also likely an ancient one.Este estudio biosistemático de Corethrellidae a nivel Mundial, con su único género Corethrella, proporciona una completa recopilación de todo lo conocido para el grupo, tanto desde el punto de vista taxonómico como bionómico. Las descripciones de cada especie se realizan primariamente sobre la base de adultos, resumen toda la información bionómica y proveen un mapa donde se muestra su distribución. Se brindan claves para especie de cada región. Se reconoce un total de 97 especies, 52 de las cuales son nuevas. Se describen siete especies fósiles, siendo dos de ellas nuevas para la Ciencia. Para una fácil referencia, todas las especies son catalogadas en una tabla, incluyendo 13 nuevos sinónimos. Debido a que sus tipos se hallan dañados o perdidos, siete especies actuales ostentan un status incierto. De acuerdo a la especie, son designados lectotipos o paralectotipos de las siguientes especies: C. inepta (Annandale), C. pallitarsis Edwards, C. picticollis Edwards, C. ananacola Dyar, C. calathicola Edwards, y C. brakeleyi (Coquillett). El análisis cladístico interpreta la mayoría de las especies actuales y fósiles (algunas no pueden ser interpretadas actualmente) y provee la base para interpretaciones zoogeográficas y bionómicas. Las especies de Corethrella se hallan entre 50°N y 50°S, aunque la mayoría se encuentran entre 30°N y 30°S y por debajo de 1500 metros de elevación. Debido a que las hembras adultas son atraídas por el llamado de ranas macho y se alimentan de su sangre, las especies están restringidas a las áreas donde se hallan ranas. Los patrones filogenéticos sugieren conecciones Gondwánicas para los linajes más antiguos del género. Al menos un linaje se ha dispersado desde el Nuevo Mundo hacia el sudeste de Asia, y algunas especies se hallan en islas volcánicas del Caribe, indicando otras instancias de dispersión. Con seguridad aún quedan muchas más especies por ser descubiertas. Los patrones filogenéticos indican que los inmaduros de las especies de Corethrella se han movido repetidamente entre habitats ubicados a nivel del suelo y fitotelmata, siendo probablemente
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Demir, Nusret, and Çiler Çilingiroğlu. "Assessing the Impact of the Türkiye February 2023 Earthquakes on Cultural Heritage Sites: A Multi-Disciplinary Approach Utilizing ARIA Maps and Social Media Collaboration." International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLVIII-1-2024 (May 10, 2024): 117–22. http://dx.doi.org/10.5194/isprs-archives-xlviii-1-2024-117-2024.
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Abstract. The earthquakes that occurred in our country on February 6, 2023, significantly damaged and destroyed cultural and historical assets. The Habib-i Nejjar Mosque in Antakya and other important historical sites suffered significant damage. This study provides a comprehensive account of the post-earthquake efforts carried out by volunteers from various disciplines, including archaeology, cartography, space sciences, and architecture, using social media platforms. The volunteers created an extensive database for cultural and archaeological sites in all 11 provinces that were declared disaster zones. This database made it easier to conduct a thorough evaluation of the damage. The database was augmented with surface displacement data, enabling an analysis of damage levels with the exactitude facilitated by the gathered information. The utilization of the Advanced Rapid Imaging and Analysis (ARIA) maps was pivotal in this study. The maps, created through partnerships between NASA and different space agencies, offer intricate satellite imagery and analysis of surface displacement. This is essential for evaluating the effects of earthquakes on cultural heritage sites. The utilization of ARIA maps in this study facilitated an accurate assessment of the seismic impact on cultural and historical resources. Additionally, Sentinel 1 images are used to generate displacement maps with the use of the LICSAR tool and the SBAS method. The study examined the state of about 1500 cultural heritage sites in 11 provinces in the aftermath of the earthquake. The report incorporated data from media coverage and input from relevant parties present at the scene, providing a thorough assessment of the situation following the disaster. For instance, the research revealed substantial shifts at prominent locations, like the UNESCO World Heritage site of Arslantepe in Malatya. This site experienced a displacement of over one meter towards the south and 75 cm towards the west, along with a subsidence of approximately 10 cm in the surrounding area. Furthermore, the study presented a visual representation that depicted the quantity of impaired cultural heritage sites in every province, providing a comprehensive evaluation of the impacted cultural and archaeological resources. This comprehensive strategy not only emphasized the magnitude of harm to cultural heritage but also emphasized the significance of interdisciplinary cooperation in disaster response and heritage preservation.
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Marcossi Cintra, Michel, Naira Favoretto, Alef Janguas, Filipe Lopes, Christoph Kaeppler, and Fabiana Faleiros. "Análise da acessibilidade, acessos e certificações das informações de um fórum virtual de saúde." Revista Portuguesa de Enfermagem de Reabilitação 2, no. 2 (December 6, 2019): 12–19. http://dx.doi.org/10.33194/rper.2019.v1.n2.02.4538.
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Introdução: A Espinha Bífida (EB) é a mais frequente malformação congênita no mundo, sendo responsável por importantes sequelas neurológicas, compatível com a vida. Diante disso, faz-se necessário identificar e desenvolver tecnologias educacionais, que auxiliem na capacitação e no apoio a indivíduos com EB e seus familiares. Nessa direção, foi desenvolvido um fórum virtual para indivíduos com EB e seus familiares, o MieloFórum. Objetivo: A proposta deste estudo é avaliar os acessos, a acessibilidade dos seus usuários e garantir uma certificação de qualidade ao mesmo. Método: Para a análise de erros de HTML foram coletados os erros de acessos do MieloFórum, analisado os acessos e submetido a uma certificação de qualidade. Resultados e discussões: o fórum foi desenvolvido e avaliado, sendo encontrado o total de 28 problemas no código do fórum, levando em consideração as regras de padronização do World Wide Web Consortium mostrou-se abrangente em acessos no período analisado e submetido a certificação de qualidade. Foram mais de 1500 acessos em 7 meses com uma demanda em diversos países. Conclusão: A submissão do MieloFórum em uma ferramenta de análise da acessibilidade mostrou-se útil para o julgamento e a correção dos problemas identificados, potencializando-o juntamente com a certificação de qualidade. Descritores: Reabilitação,Acesso aos Serviços de Saúde, Fórum de Saúde.
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Berendsent, H. J. A. "History of geological mapping of the Holocene Rhine-Meuse delta, the Netherlands." Netherlands Journal of Geosciences 86, no. 3 (September 2007): 165–77. http://dx.doi.org/10.1017/s0016774600077787.
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AbstractA brief overview is given of the history of geological mapping of the Holocene Rhine-Meuse delta. The first accurate map of the delta, based on field observations, was made by Vink (1926). The geological map of the Netherlands, scale 1 : 50,000, made by the ‘Geologische Stichting’ (1927 – 1938) under the supervision of P. Tesch totally neglected Vink’s work, and was a step backwards with regard to the mapping of the Holocene delta. Between 1940 and 1965, the Wageningen group of soil scientists produced detailed regional soil maps, that had a strong ‘geogenetic’ component. In the 1960’s a revolutionary ‘profile type legend’ was introduced by the Netherlands’ Geological Survey. This allowed to map not only the outcropping sediments, but the whole Holocene succession, which gave more insight into the geological history. Over the past 30 years, the Rhine-Meuse delta has been studied extensively by students of physical geography at Utrecht University. More than 250,000 borehole descriptions, 1500 14C dates and over 36,000 archeological artifacts with associated ages (collected by the National Service for Archaeological Heritage) have accumulated, resulting in the largest database of a delta in the world. The production of detailed maps has been crucial to the solution of many scientific problems. The use of GIS has greatly enhanced geological and geomorphological mapping, and subsequently, understanding of the evolution of the Holocene Rhine-Meuse delta. A new detailed digital elevation map of the Netherlands, based on very accurate laser-altimetry data, will enable us to map larger areas in greater detail, with greater accuracy, and in a much shorter period of time.
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Vigosa-Mercado, J. Luis, Alfonso Delgado-Salinas, Leonardo O. Alvarado Cárdenas, and Luis E. Eguiarte. "Revision of the genus Agrostis (Poaceae, Pooideae, Poeae) in Megamexico." PhytoKeys 230 (August 11, 2023): 157–256. http://dx.doi.org/10.3897/phytokeys.230.105878.
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Agrostis is one of the most diverse genera of the Poaceae, including ca. 198 species, principally distributed in cold and temperate regions of the world, but also found in the high mountains of the tropics. We present a revision based on morphoanatomical evidence, for the biogeographic region known as Megamexico 3 (i.e., Mexico including the desert areas of southern USA and the Central America territory, to northern Nicaragua). We include taxonomic descriptions and an identification key for the found taxa, maps with the known geographical distribution of the species, and figures with the morphoanatomical characteristics, elevation and phenology. Agrostis is represented in the study zone by 20 species, of which four are endemic and three are introduced. Most records of the genus are distributed in the mountains, above 1500 m a.s.l., in open areas of temperate forests, with conifers and Quercus. Specimens with spikelets occur year round, but most records occur during the wet season, in the months of July to October. We propose a preliminary conservation assessment for each species in the study zone, according to the International Union for Conservation of Nature categories: one with Deficient Data (DD), six as Endangered (EN), two as Vulnerable (VU), and 11 as Least Concern (LC).
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Lak, Martijn. "The Cambridge World History of Violence Volume I. The Prehistoric and Ancient Worlds. Ed. by Garrett G. Fagan et al. Cambridge University Press, Cambridge 2020. xvii, 739 pp. Ill. Maps. £120.00. (E-book: $42.00.) - The Cambridge World History of Violence Volume II. 500–1500 CE. Ed. by Matthew S. Gordon, Richard W. Kaeuper, and Harriet Zurndorfer. Cambridge University Press, Cambridge 2020. xiv, 708 pp. Ill. Maps. £120.00. (E-book: $42.00.) - The Cambridge World History of Violence Volume III. 1500–1800 CE. Ed. by Robert Antony, Stuart Carroll, and Caroline Dodds Pennock. Cambridge University Press, Cambridge 2020. xv, 716 pp. Ill. Maps. £120.00. (E-book: $42.00.) - The Cambridge World History of Violence Volume IV. 1800 to the Present. Ed. by Louise Edwards, Nigel Penn, and Jay Winter. Cambridge University Press, Cambridge 2020. xiv, 680 pp. Ill. Maps. £120.00. (E-book: $42.00.)." International Review of Social History 67, no. 3 (November 25, 2022): 554–58. http://dx.doi.org/10.1017/s0020859022000694.
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Tubiello, Francesco N., Giulia Conchedda, Leon Casse, Pengyu Hao, Giorgia De Santis, and Zhongxin Chen. "A new cropland area database by country circa 2020." Earth System Science Data 15, no. 11 (November 15, 2023): 4997–5015. http://dx.doi.org/10.5194/essd-15-4997-2023.
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Abstract. We describe a new dataset of cropland area circa the year 2020, with global coverage and with data for 221 countries and territories and 34 regional aggregates. Data are generated from geospatial information on the agreement–disagreement characteristics of six open-access high-resolution cropland maps derived from remote sensing. The cropland area mapping (CAM) aggregation dataset provides information on (i) mean cropland area and its uncertainty, (ii) cropland area by six distinct cropland agreement classes, and (iii) cropland area by specific combinations of underlying land cover product. The results indicated that world cropland area is 1500 ± 400 Mha (mean and 95 % confidence interval), with a relative uncertainty of 25 % that increased across regions. It was 50 % in Central Asia (40 ± 20 Mha), South America (180 ± 80 Mha), and Southern Europe (40 ± 20 Mha) and up to 40 % in Australia and New Zealand (50 ± 20 Mha), Southeastern Asia (80 ± 30 Mha), and Southern Africa (16 ± 6 Mha). Conversely, cropland area was estimated with better precision, i.e., smaller uncertainties in the range 10 %–25 % in Southern Asia (230 ± 30 Mha), Northern America (200 ± 40 Mha), Northern Africa (40 ± 10 Mha), and Eastern Europe and Western Europe (40 ± 10 Mha). The new data can be used to investigate the coherence of information across the six underlying products, as well as to explore important disagreement features. Overall, 70 % or more of the estimated mean cropland area globally and by region corresponded to good agreement of underlying land cover maps – four or more. Conversely, in Africa cropland area estimates found significant disagreement, highlighting mapping difficulties in complex landscapes. Finally, the new cropland area data were consistent with FAOSTAT (FAO, 2023) in 15 out of 18 world regions, as well as for 114 out of 182 countries with a cropland area above 10 kha. By helping to highlight features of cropland characteristics and underlying causes for agreement–disagreement across land cover products, the CAM aggregation dataset may be used as a reference for the quality of country statistics and may help guide future mapping efforts towards improved agricultural monitoring. Data are publicly available at https://doi.org/10.5281/zenodo.7987515 (Tubiello et al., 2023a).
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Mayer, Adolfo Rafael Souza Braz, Marcela Vaz Ramos, Juliana Paiva Fontoura, and Thais Camila Alves Lessa Duran. "INCIDÊNCIA DE CARCINOMA EPIDERMÓIDE DO COLO DE ÚTERO EM RONDÔNIA ENTRE 2006 E 2015." REVISTA FIMCA 11, no. 1 (March 13, 2024): 11–13. http://dx.doi.org/10.37157/fimca.v11i1.810.
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Introdução: O câncer de colo de útero é o 4° mais comum em nível global e a 4ª neoplasia que mais mata mulheres no mundo. O seu tipo mais comum é o epidermóide, que é facilmente diagnosticado através da colpocitologia oncótica, tendo bom prognóstico quando identificado precocemente. Objetivo: Verificar a incidência de carcinoma epidermóide no estado de Rondônia, seus níveis de invasão e faixas etárias de acometimento. Materiais e Métodos: Trata-se de um estudo transversal utilizando dados do SISCOLO acerca dos carcinomas epidermóides diagnosticados entre janeiro de 2006 e fevereiro de 2015, avaliando suas variáveis. Resultados e Discussão: 16,9% (185) das malignidades diagnosticadas no período eram cânceres epidermóides. Destes, 6,5% (12) foram descritos como microinvasores, 77,8% (144) como invasores e em 15,7% (29) foi impossível avaliar presença de nível de invasão. As faixas etárias entre 34-64 anos foram as mais acometidas nos microinvasores e invasores, e > 65 anos nos carcinomas com avaliação de invasão prejudicada. Assim, é importante a discussão acerca da vacina contra o HPV e a redução da morbimortalidade pela malignidade epidermóide, bem como o rastreio como atenuante desse índice. Conclusão: A indicação de colpocitologia oncótica de acordo com as indicações do Ministério da Saúde é essencial para diagnóstico e manejo precoce do carcinoma epidermóide, sendo a caracterização neoplásica através do exame anatomopatológico também muito importante para a tomada de decisões acerca do tratamento. Assim, é importante avaliar quais obstáculos levam à baixa adesão do exame preventivo, a fim de saná-los, reduzindo índice de morbimortalidade desta neoplasia. Introduction: Cervical cancer is the 4th most common cancer globally and the 4th cancer that kills most women in the world. Its most common type is epidermoid, which is easily diagnosed through oncotic cytology and has a good prognosis when identified early. Objective: To verify the incidence of squamous cell carcinoma in the state of Rondônia, its levels of invasion, and age ranges of involvement. Materials and Methods: This is a cross-sectional study using data from SISCOLO on squamous cell carcinomas diagnosed between January 2006 and February 2015, evaluating their variables. Results and Discussion: 16.9% (185) of malignancies diagnosed in the period were epidermoid cancers. Of these, 6.5% (12) were described as microinvaders, 77.8% (144) as invaders, and in 15.7% (29) it was impossible to assess the presence of an invasion level. The age groups between 34-64 years were the most affected in microinvaders and invaders, and > 65 years in carcinomas with impaired invasion assessment. Therefore, it is important to discuss the HPV vaccine and the reduction of morbidity and mortality due to epidermoid malignancy, as well as screening as a mitigating factor. Conclusion: The indication of oncotic colpocytology under the instructions of the Ministry of Health is essential for the early diagnosis and management of squamous cell carcinoma, with neoplastic characterization through anatomopathological examination also being very important for making treatment decisions. Therefore, it is important to evaluate which obstacles lead to low adherence to preventive testing, to remedy them, reducing the morbidity and mortality rate of this neoplasm.
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Tignor, Robert L. "Maize and Grace: Africa's Encounter with a New World Crop, 1500–2000. By James C. McCann. Cambridge: Harvard University Press, 2005. xiii + 289 pp. Index, notes, bibliography, illustrations, maps, photographs, tables. Cloth, $27.95. ISBN: 0-674-01718-8." Business History Review 79, no. 3 (2005): 689–91. http://dx.doi.org/10.2307/25097104.
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Alexander, Ryan M. "The Mexican Heartland: How Communities Shaped Capitalism, a Nation, and World History, 1500–2000. ByJohn Tutino. Princeton: Princeton University Press, 2018. viii + 499 pp. Maps, figures, tables, bibliography, appendix, notes, index. Cloth, $39.50. ISBN: 978-0-691-17436-5." Business History Review 92, no. 3 (2018): 595–97. http://dx.doi.org/10.1017/s0007680518000958.
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Borucki, Alex. "Black Ranching Frontiers: African Cattle Herders of the Atlantic World, 1500–1900. ByAndrew Sluyter. New Haven and London: Yale University Press, 2012. xii + 308 pp. Tables, photographs, maps, illustrations, figures, notes, index. Cloth, $45.00. ISBN: 978-0-300-17992-7." Business History Review 89, no. 4 (2015): 779–81. http://dx.doi.org/10.1017/s0007680515001178.
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Housley, Norman. "The western mediterranean kingdoms 1200–1500. The struggle for dominion. By David Abulafia (The Medieval World.) Pp. xix+300 incl. 4 maps and 4 genealogical tables. Longman: London–New York, 1997. £14.99 (paper), 0 582 07821 0; 0 582 07820 2." Journal of Ecclesiastical History 50, no. 1 (January 1999): 131–77. http://dx.doi.org/10.1017/s0022046998387126.
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Roy, Tirthankar. "PimdeZwart and Jan LuitenvanZanden, The origins of globalization: world trade in the making of the global economy, 1500–1800 (Cambridge: Cambridge University Press, 2018. Pp. xvi+338. 34 figs. 15 tabs. 9 maps. ISBN 9781108426992 Hbk. £64.99; ISBN 9781108447133 Pbk. £21.99)." Economic History Review 72, no. 4 (October 14, 2019): 1521–22. http://dx.doi.org/10.1111/ehr.12924.
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Meyers, Debra. "North America/Atlantic World - Douglas Catterall and Jodi Campbell, eds. Women in Port: Gendering Communities, Economies, and Social Networks in Atlantic Port Cities, 1500-1800. Brill, 2012. 443 pp., 3 halftones, 2 maps, bibliography, and index. ISBN: 978 90 04 23317 1 (hbk.). $179.00." Itinerario 37, no. 2 (August 2013): 195–97. http://dx.doi.org/10.1017/s0165115313000685.
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Irigoin, Alejandra. "Pim De Zwart and Jan Luiten van Zanden. The Origins of Globalization. World Trade in the Making of the Global Economy, 1500–1800. [New Approaches to Social and Economic History.] Cambridge University Press, Cambridge [etc.] 2018. xv, 338 pp. Ill. Maps. £64.99. (Paper: £21.99; E-book: $24.00)." International Review of Social History 64, no. 3 (November 25, 2019): 533–36. http://dx.doi.org/10.1017/s0020859019000609.
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Khudhair, Haneen, Rand Ahmed, Rim Hussein, Hassain Ibrahim, and Omer Hassain. "Studying of Physio-chemical Properties of The Groundwater in AL-A’lam City." Tikrit Journal of Engineering Sciences 27, no. 4 (October 10, 2020): 31–38. http://dx.doi.org/10.25130/tjes.27.4.04.
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he present study was conducted for eight wells that are distributed in A’alam subdistrict in Salah al-Din province to assess the groundwater quality in this area. Water samples from these wells were taken during three months periods, one sample per month. Some physical and chemical properties of the water samples were tested by conducting on-site and laboratory tests. The water temperatures of the wells were recorded to assess its relationship with many properties of the water, including basal. The results indicated that the water of the studied wells was warm during the study period, and its temperature range was (19-24) ° C. The pH was measured and also its values were in the range (7.44-8.4). The values of total dissolved solids exceeded the permissible limits, with a minimum value of (1930) mg/L which is higher than the permissible limit in the drinking water relating to the Iraqi standard and the specifications of the World Health Organization (WHO) and the American Environmental Protection Agency (USEPA), (1000) mg/L. This increase led to a significant increase in the electrical conductivity values, which reached its lowest recorded value of (3940) microsmins/cm, which is above the permissible limit (1500) microsmins/cm. The concentration of chloride ion, which is in the range (482.7-1053) mg/L and sulfur ions, which recorded its lowest value (411) mg/L, and also this exceeded the permissible limits for both ions (250) mg/L according to the Iraqi standard and WHO standards. The study covered all the studied wells water, and its depth are found in the range (80-160) meters, which is very hard water, with a concentration of (180) mg/L. The results indicate that the water was permanently exposed to pollution and is far from optimal for most of the time. Geographic information systems (GIS) were used to produce spatial maps of the study area showing the distribution of the characteristics studied, thus providing a future database for the region, which could be used to diagnose pollution wherever it would be found
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Vangu, Germaine Paka, Kitume Ngongo Mobambo, Bonaventure Aman Omondi, and Charles Staver. "Evaluation des performances du plantain en systèmes de cultures associées pérennes en zone savanicole au Kongo central en République Démocratique du Congo." International Journal of Biological and Chemical Sciences 17, no. 4 (September 19, 2023): 1443–55. http://dx.doi.org/10.4314/ijbcs.v17i4.13.
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Le système de culture du plantain suscite un intérêt croissant à travers le monde scientifique, du fait de sa contribution à la productivité et à la durabilité de la culture. Diverses associations sont répertoriées en Afrique de l’Ouest et du Centre, mais la plupart d’entre elles sont limitées dans l’espace et dans le temps. L’objectif vise à élargir la gamme de systèmes de culture à base du bananier plantain en zone savanicole au Kongo central en RDC. Pueraria et vétiver ont été les deux cultures utilisées comme cultures intercalaires avec le plantain pendant trois cycles. Ils ont été évalués dans les conditions du centre de recherche, en comparaison avec la monoculture de banane plantain utilisée comme témoin. Les plantains associés à pueraria et au vétiver ont montré de bonnes performances agronomiques avec des poids moyens de régimes de 14711,98±1118,71 g ; 13532,11±1113 g respectivement, contre 11446,67±1098,58 g pour le témoin et des poids moyens de doigts de 210,29±15,7 g et 190,19±16,6 g respectivement pour le pueraria et le vétiver, contre 158,18±12,6 g pour le temoin. Les plantains associés au vétiver ont également montré une circonférence de 69±11,21 cm, plus grande que le témoin (66,3±1,05) y compris les autres associations. Le système plantain-pueraria-vétiver n’est pas plus performant.
English title: Evaluation of plantain performance in perennial associated cropping systems in the savannah zone in Kongo central in Democratic Republic of Congo
Plantain cropping system arouse an increasing interest across the scientific world, due to his contribution to banana plantain productivity and cultivation sustainability. Various associations are listed in West and Central Africa, but most of them are limited in the space and in the time. This study aims to expand the range of plantain cropping systems in the savannah zone in Kongo central in DRC. Pueraria and vetiver were the two crops used as intercrops with plantain during three cycles. They were assessed under research center conditions, in comparison with monoculture of plantain used as control. Plantain plants associated with pueraria and vetiver showed good agronomic performance with average bunches weights of 14711,98±1118,71 g ; 13532,11±1113 g respectively, against 11446,67±1098,58 g of the control and with average fingers weights of 210,29±15,7 g for pueraria and 190,19±16,6 g for vetiver, against 158,18±12,6 g of the control. Plantain plants associated with vetiver showed also a circumference of 69±11,21 cm, better than the control (66,3±1,05) and others systems. Plantain-pueraria-vetiver system is not more performant.
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Wang, Ziyi, Xiyou Su, and Shiwei Mao. "Single-Species Leaf Detection against Complex Backgrounds with YOLOv5s." Forests 15, no. 6 (May 21, 2024): 894. http://dx.doi.org/10.3390/f15060894.
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Accurate and rapid localization and identification of tree leaves are of significant importance for urban forest planning and environmental protection. Existing object detection neural networks are complex and often large, which hinders their deployment on mobile devices and compromises their efficiency in detecting plant leaves, especially against complex backgrounds. To address this issue, we collected eight common types of tree leaves against complex urban backgrounds to create a single-species leaf dataset. Each image in this dataset contains only one type of tree but may include multiple leaves. These leaves share similar shapes and textures and resemble various real-world background colors, making them difficult to distinguish and accurately identify, thereby posing challenges to model precision in localization and recognition. We propose a lightweight single-species leaf detection model, SinL-YOLOv5, which is only 15.7 MB. First, we integrated an SE module into the backbone to adaptively adjust the channel weights of feature maps, enhancing the expression of critical features such as the contours and textures of the leaves. Then, we developed an adaptive weighted bi-directional feature pyramid network, SE-BiFPN, utilizing the SE module within the backbone. This approach enhances the information transfer capabilities between the deep semantic features and shallow contour texture features of the network, thereby accelerating detection speed and improving detection accuracy. Finally, to enhance model stability during learning, we introduced an angle cost-based bounding box regression loss function (SIoU), which integrates directional information between ground-truth boxes and predicted boxes. This allows for more effective learning of the positioning and size of leaf edges and enhances the model’s accuracy in detecting leaf locations. We validated the improved model on the single-species leaf dataset. The results showed that compared to YOLOv5s, SinL-YOLOv5 exhibited a notable performance improvement. Specifically, SinL-YOLOv5 achieved an increase of nearly 4.7 percentage points in the mAP@0.5 and processed an additional 20 frames per second. These enhancements significantly enhanced both the accuracy and speed of localization and recognition. With this improved model, we achieved accurate and rapid detection of eight common types of single-species tree leaves against complex urban backgrounds, providing technical support for urban forest surveys, urban forestry planning, and urban environmental conservation.
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Heck, Paul L. "Alfred Hiatt, ed., Cartography between Christian Europe and the Arabic-Islamic World, 1100–1500: Divergent Traditions. (Maps, Spaces, Cultures 3.) Leiden: Brill, 2021. Pp. xiii, 235; color and black-and-white figures. $113. ISBN: 978-9-0044-4491-1. Table of contents available online at https://brill.com/view/title/58674." Speculum 97, no. 4 (October 1, 2022): 1204–6. http://dx.doi.org/10.1086/722064.
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Roque, Vanessa Maria Nunes, and Nora Manoukian Forones. "Avaliação da qualidade de vida e toxicidades em pacientes com câncer colorretal tratados com quimioterapia adjuvante baseada em fluoropirimidinas." Arquivos de Gastroenterologia 43, no. 2 (June 2006): 94–101. http://dx.doi.org/10.1590/s0004-28032006000200007.
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RACIONAL: O câncer colorretal é a quarta causa de câncer no Brasil e o 5-fluourouracil uma das principais drogas usadas no tratamento adjuvante e paliativo dessa doença. A toxicidade da quimioterapia e as alterações de qualidade de vida, causadas pela própria doença e pelo tratamento, são motivo de muitos estudos. OBJETIVO: Avaliar nos doentes com câncer colorretal em tratamento quimioterápico, a toxicidade e possíveis alterações da qualidade de vida. MÉTODOS: Durante o período de março de 2001 a maio de 2003 no Ambulatório de Oncologia da Disciplina de Gastroenterologia Clínica da Universidade Federal de São Paulo, foram acompanhados 45 pacientes com câncer colorretal em tratamento quimioterápico adjuvante ou paliativo com 5-fluourouracil e ácido folínico durante seis ciclos. A toxicidade gastrointestinal e hematológica foi analisada utilizando-se as Recomendações para a Graduação da Toxicidade Aguda e Subaguda. Após o término de cada ciclo quimioterápico, os resultados foram anotados de acordo com os respectivos graus que variaram entre 0 e 4. A qualidade de vida foi pesquisada pelo questionário WHOQOL bref (World Health Organization Quality of Life) que consta de 26 questões e é composto por 4 domínios: físico, psicológico, relações sociais e meio ambiente, no início, no 3° e no 6° ciclo de tratamento. RESULTADOS: Entre os 45 pacientes, 28 eram do sexo masculino, a média de idade foi de 58,4 anos (34 a 79 anos). Segundo a classificação da União Internacional Contra o Câncer, 34 (75,6%) eram estádio II ou III e 11 estádio IV (24,4%). Quanto à localização, 64,4% eram de cólon. Em 57,7% a quimioterapia foi adjuvante e nos demais paliativa. As toxicidades mais comumente encontradas foram náuseas (42%), diarréia (38%) e neutropenia (15,7%). Não houve diferença significante entre os graus de toxicidade nos diferentes ciclos, assim como entre os doentes em tratamento adjuvante ou paliativo. Quanto à qualidade de vida foram observadas alterações significantes nos domínios físico e psicológico quando comparadas a primeira com a segunda ou a primeira com a terceira aplicação do questionário. Não foi encontrada alteração da qualidade de vida entre os doentes em quimioterapia adjuvante quando comparada aos em tratamento paliativo. Independente da indicação terapêutica, a média dos escores de qualidade de vida diminuiu em relação aos domínios físico e social na terceira aplicação do teste. CONCLUSÃO: As toxicidades gastrointestinais foram mais freqüentes que as hematológicas com o esquema utilizado. A qualidade de vida diminuiu após o início da quimioterapia em relação à atividade física e psicológica. No estudo da média dos escores observou-se queda dos mesmos nos domínios físico e social. A análise do questionário não mostrou alteração de qualidade vida quando comparados os doentes em tratamento paliativo com os em adjuvância.
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Wall, Alison. "New worlds, lost worlds. The rule of the Tudors, 1485–1603. By Susan Brigden. (The Penguin History of Britain, 5.) Pp. xiv+434 incl. 7 ills. London: Allen Lane–Penguin, 2000. £20. 0 713 99067 8 Figures in the landscape. Rural society in England, 1500–1700. By Margaret Spufford. (Collected Studies, p. 666.) Pp. xii+364 incl. frontispiece, 4 maps and 13 figs. Aldershot: Ashgate, 2000. £59.50. 0 86078 804 0." Journal of Ecclesiastical History 53, no. 2 (April 2002): 333–428. http://dx.doi.org/10.1017/s0022046902554245.
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Frederick, Bruce C., Mike D. Blum, John W. Snedden, and Richard H. Fillon. "Early Mesozoic synrift Eagle Mills Formation and coeval siliciclastic sources, sinks, and sediment routing, northern Gulf of Mexico basin." GSA Bulletin 132, no. 11-12 (April 24, 2020): 2631–50. http://dx.doi.org/10.1130/b35493.1.
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Abstract The sedimentary architecture and provenance of the early Mesozoic incipient northern Gulf of Mexico basin remains controversial due to both lack of outcrop exposure and sample scarcity across the southern United States with subcrop depths approaching 6 km. The Eagle Mills Formation and coeval deposition across the northern Gulf of Mexico provides both a stratigraphic foundation for some ∼15-km-thick overlying Mesozoic and Cenozoic deposits, and a coeval pre-salt equivalent for southern synrift deposits, in one of the most economically significant hydrocarbon basins in the world. This study presents more than 3200 new detrital zircon U-Pb analyses from sixteen Late Triassic pre-salt, siliciclastic, subcrop well samples, and combines over 14,000 linear kilometers of 2-D multi-channel seismic reflection data, 1511 geophysical well logs, and biostratigraphic data from 2478 wells to construct basin-scale pre-salt isochore and structure maps spanning the northern Gulf of Mexico margin from Florida to the USA-Mexican border. The data show that incipient Gulf of Mexico paleodrainage pathways held individual distinctions between basement sources and tectonic controls in three primary regions across the northern Gulf of Mexico: (1) The western Gulf of Mexico paleodrainage extended from the Central Texas uplift highlands to the submarine Potosi Fan on the western margin of Laurentia with local tributary sources from the East Mexico Arc, Yucatán/Maya, and Marathon-Ouachita provinces as evidenced by inverse Monte Carlo unmixing of peri-Gondwanan (ca. 700–500 Ma), Appalachian/Ouachita (500–280 Ma), Grenville (1250–950 Ma), and Mid-Continent/Granite-Rhyolite Province (1500–1300 Ma) detrital zircon ages. Isochore and associated geophysical well and seismic data suggest that by Early Jurassic time this depocenter had shifted into the present-day western Gulf of Mexico as East Mexico Arc development continued. (2) Southerly drainage in the north-central Gulf of Mexico region bifurcated around the Sabine and Monroe uplifted terranes with southwestern flow characterized by peri-Gondwanan detrital zircon ages from late Paleozoic accreted basement or discrete flexural successor basins, and southeastern fluvial networks distinguished by traditional North American basement province sources including Grenville, Mid-Continent, and Yavapai-Mazatzal. (3) Eastern Gulf of Mexico regional paleodrainage, with regional southern flow dictated by the brittle extensional tectonics of the South Georgia Rift as well as the regional southern flexure of the South Florida Basin, resulted in almost all pre-salt detrital zircon siliciclastic ages from this region to be dominated by local Gondwanan/peri-Gondwanan aged sources including the proximal Suwannee terrane and Osceola Granite complex. These regional, synrift sediment provenance models provide the first critical allochthonous evidence of Late Triassic–Early Jurassic paleodrainage stemming from the Appalachian-Ouachita hinterlands into the incipient northern Gulf of Mexico basin with critical implications for pre-salt hydrocarbon exploration and carbon sequestration reservoir potential.
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Хисамов, Р. С., Ф. М. Латифуллин, Р. З. Саттаров, С. В. Смирнов, В. М. Ситникова, and Ф. Ф. Латифуллин. "Computer-aided search and analysis of intervals with high current oil recovery factor in Kynovskian and Pashiyskain formations of romashkinskoe oil field." Нефтяная провинция, no. 1(1) (July 2, 2015): 12–31. http://dx.doi.org/10.25689/np.2015.1.12-31.
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Ромашкинское нефтяное месторождение входит в десятку крупнейших месторождений мира. Наиболее значимыми по величине запасов являются залежи нефти верхнего терригенного девона - кыновский (Д ) и пашийский (Д ) горизонты. Основная часть объектов (площадей) пашийско-кыновского горизонта Ромашкинского месторождения вступила в позднюю стадию разработки, которая характеризуется высокой обводненностью добываемой продукции, низкими темпами отбора нефти, достижением по многим участкам высокого значения текущего коэффициента извлечения нефти (КИН), ухудшением структуры запасов. Пробуренный фонд по анализируемому объекту составляет более 23 тыс. скважин. Скважины вскрывают более 82 тыс. нефтенасыщенных интервалов (участков), по которым необходимо проанализировать степень выработанности их запасов. Обработать такой объем информации вручную за приемлемый срок не представляется возможным. Поэтому для решения поставленной задачи было решено использовать геолого-технологическую модель АРМ «ЛАЗУРИТ». Составлены алгоритмы и компьютерные программы для подсистемы «Анализ остаточных запасов нефти» АРМ геолога «ЛАЗУРИТ», в нее добавлена задача «Анализ участков с высоким КИН». В автоматизированном режиме по всем площадям Ромашкинского месторождения выделены участки с аномально высоким текущим КИН. В геологическом разрезе на исследуемых площадях рассмотрены три пачки пластов: пласт Д кыновского горизонта, верхняя (Д а-Д б3) и нижняя (Д в-Д д) пачки пластов пашийского горизонта. Всего проанализирован 82881 участок, из них - 16440 являются участками с высоким значением КИН. По разрезу наибольшее количество участков с высоким значением КИН приходится на верхнюю пачку пластов (Д а-Д б3) - 9013, наименьшее приходится на пачку Д - 918. 13683 скважины (58,12 % от общего фонда) в разрезе пластов горизонта Д + Д не содержат ни одного участка с высоким значением КИН. 5959 скважин (25,31 %) содержат один участок, 2362 скважины (10,03 %) - два, 986 скважин (4,19 %) - три, 389 скважин (1,65 %) - четыре, 119 скважин (0,51 %) - пять участков с высоким значением КИН в разрезе. По всем участкам с высоким значением КИН оценены начальные и остаточные запасы нефти, вычислены технологические показатели разработки. По величине остаточных подвижных запасов нефти участки разделены на три группы: - полностью выработанные (менее 1,5 тыс. т); - сильно выработанные (более 1,5 и менее 7,5 тыс. т); - относительно слабо выработанные (не менее 7,5 тыс. т). Всего по кыновско-пашийскому горизонту Ромашкинского месторождения 212 участков являются относительно слабо выработанными. Эти участки содержат начальных и остаточных подвижных запасов 40,709 и 2,591 млн. т соответственно. Средняя проницаемость по слабо выработанным участкам равна 1,073 мкм , средняя нефтенасыщенная толщина - 4,5 м, общая площадь составляет 6294 га, средний коэффициент охвата заводнением равен 0,933 доли ед. Построены карты плотности остаточных подвижных запасов нефти с отображением годовых отборов и закачки с выделением участков с аномально высоким текущим КИН. Данные карты использованы для выработки рекомендаций по доразработке участков с высоким КИН. The Romashkinskoye oil field is among the top ten largest world oil fields. In terms of oil reserves, the most important are the Upper Devonian Kynovskian and Pashiyskain terrigenous formations (D and D ). Most of the development targets (areas) of the Kynovskian and Pashiyskain formations have entered the stage of maturity characterized by high water cut of the wellstream, low production rates, high values of oil recovery factor, deteriorated structure of reserves. In the area under study, more than 23 000 wells have been drilled penetrating more than 82 000 productive intervals. The objective is to analyze the extent of reserves depletion in all of these intervals. Manual processing of a bulk of information as huge as that does not seem likely in any reasonable term. The task was solved with the help of a proprietary geologic and reservoir simulator LAZURIT workstation. Algorithms and computer programs for the subsystem Analysis of Residual Oil Reserves were designed; also a new task-Analysis of Areas with High Oil Recovery Factor-was added in the subsystem. This helped to identify all intervals with high current oil recovery in the Romashkinskoye field. The geologic cross-section of three members was analyzed: the Kynovskian formation, the upper and lower members of the Pashiyskain formation. All in all, 82 881 intervals were analyzed, including 16 440 intervals with high current oil recovery factor. Majority of intervals with high current oil recovery factor fall within the upper member of the Pashiyskain formation, the least number is in the Kynovskian formation. In the cross-section of D + D formations, 13 683 wells (58.12 % of total well inventory) have no intervals with high current oil recovery factor; 5 959 wells (25.31 %) have one interval, 2362 wells (10.03 %) have two intervals, 986 wells (4.19 %) have three intervals, 389 wells (1.65 %) have four intervals, and 119 wells (0.51 %) have five intervals with high current oil recovery factor. OOIP and ROIP were estimated for all intervals with high current oil recovery factor, as well as production forecast. In terms of mobile residual oil-in-place, all intervals were divided into three groups: - completely depleted (less than 1500 tons ROIP); - heavily depleted (between 1500 and 7500 tons ROIP); - relatively weakly depleted (not less than 7500 tons ROIP). In the Kynovskian and Pashiyskain formations, 212 intervals fall within the latter group with OOIP and ROIP 40,709,000 and 2,591,000 tons, respectively. Average permeability of relatively weakly depleted intervals is 1.073 micron , average pay thickness is 4.5 m, total area is 6294 hectares, average sweep efficiency is 0.933. ROIP density maps were constructed reflecting annual production and injection volumes and highlighting intervals with high current oil recovery factor. Based on the information obtained, recommendations on redevelopment of intervals with high current oil recovery factor were issued.
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Catterell, W. Douglas. "Jonathan Schorsch, Swimming the Christian Atlantic: Judeoconversos, Afroiberians and Amerindians in the Seventeenth Century. 2 Vols. Volume 17, The Atlantic World: Europe, Africa and the Americas, 1500–1830, edited by Benjamin Schmidt and Wim Klooster. Leiden: Brill Academic Publishers, 2009. 17/1: x, 282 pp.; 17/2: vi, 282 pp., 3 maps, 1 table. ISBN 17/1: 978 90 04 17252 4 (hbk.); 17/2: 978 90 04 17253 1 (hbk.); 17/1-2: 978 90 04 17040 7 (hbk.). €166.00 / US $238.00." Itinerario 34, no. 2 (July 30, 2010): 155–57. http://dx.doi.org/10.1017/s0165115310000550.
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Chatzikonstantinou, Thomas, Lydia Scarfo, Christos Demosthenous, Jana Kotaskova, Gloria Iacoboni, Evangelia Minga, Dimitra Chammou, et al. "Real-World Evidence on Therapeutic Strategies and Treatment-Sequencing in Patients with Chronic Lymphocytic Leukemia: An International Study of Eric, the European Research Initiative on CLL." Blood 138, Supplement 1 (November 5, 2021): 2635. http://dx.doi.org/10.1182/blood-2021-148738.
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Abstract The use of novel small molecule inhibitors alone or in combination with anti-CD20 monoclonal antibodies for chronic lymphocytic leukemia (CLL) has raised a number of questions on efficacy, tolerability, long-term treatment adherence in patients with heterogeneous clinical features. To fill this gap, we designed a study focusing on treatment sequencing in patients with CLL in order to (i) compare the outcome of patients treated with chemoimmunotherapy (CIT) combinations in first-line versus those receiving Bruton's tyrosine kinase inhibitors (BTKi); (ii) characterize the efficacy and tolerability of venetoclax-based regimens; (ii) understand the impact of treatment sequencing when it comes to chemo-free options including venetoclax after BTKi and vice versa. Data from consecutive sets of patients diagnosed with CLL between 2000-2020 attended at 77 institutions affiliated with ERIC were collected and analyzed. Collected variables included: demographics, clinical stage at diagnosis, IGHV gene somatic hypermutation status; cytogenetic status for chromosomes 11q, 13q 17p and 12 determined by fluorescence in situ hybridization; TP53 gene mutation status; treatment; treatment response; discontinuation; reason for discontinuation; death. We included 9173 patients with a diagnosis of CLL who received at least one line of treatment. The median age at diagnosis was 67 years with a male:female ratio of 1.9. The median follow-up was 78 months (IQR, 48-120 months). Regarding novel targeted agents, 1860/9173 (20.2%) patients had received at least one line of treatment with BTKi (ibrutinib, n=1788; acalabrutinib, n=72) over the disease course; 631/9173 (6.9%) with venetoclax; and, 447/9173 (4.9%) with the PI3K inhibitor idelalisib. Seventy-nine patients were treated with both BTKi and venetoclax (59 BTKi followed by BCL2i, 20 vice versa). At last follow-up, 5870/9173 patients (64.0%) were alive, 3229/9173 (35.2%) died and 74/9173 (0.8%) were lost to follow-up. Patients treated with BTKi in first-line were enriched for TP53 aberrations [del(17p) 27.6%, TP53 mutation 26.3%] and unmutated IGHV genes (69%) and obtained an ORR of 87.7%. Of these, 136 (26.3%) discontinued treatment after a median of 1.2 years (0.07-5.98); main reasons of discontinuation were toxicity (40.5%) and failure (26.2%). Among 631 patients treated with venetoclax at any line, 100 (15.8%) received BCL2 +/- anti-CD20 as first-line; 170 (26.9%) as second line (125 previously treated with CIT, 27 with BTKi); and, 361 as third or subsequent line. ORR ranged between 71.5% (≥3 lines) with 30.5% CR/CRi to 90.3% (first-line) with 68.1% CR/CRi. Treatment discontinuation was due to toxicity in 28.6% of patients treated in the first-line, and 17.6% and 21.8% of patients treated in second and third-or-higher-line, respectively. Disease progression led to treatment discontinuation in 14.3%, 20.6% and 33.6% in first, second and third-or-higher line, respectively. CIT was used as front-line treatment in 5465 patients (59.6%). Of these, 2070 (37.9%) and 1018 (18.6%) patients received a second and third line of treatment, respectively. The great majority (865/1086 cases, 79.7%) of patients who received a second line before 2014 were retreated with CIT, most commonly Bendamustine-Rituximab (284/1086, 26.1%) and Fludarabine-Cyclophosphamide-Rituximab (252/1086, 23.2%); alemtuzumab monotherapy was used in 55/1086 (5%) of patients. After 2014, 415/984 patients (42.1%) were retreated with BTKi; 93 (9.5%) with venetoclax; 70 (7.2%) with idelalisib; 50 (5%) with Alemtuzumab monotherapy, and 315 (32%) with CIT. Similarly, in the third-or-higher line of treatment, most patients (86.3%) were retreated with CIT before 2014, while BTKi, BCL2i, and PI3Ki were mainly used after 2014 (in 43.1%, 15.7% and 14.7% of cases, respectively). Finally, our cohort included 1075 patients with TP53 aberrations. The ORR of patients receiving BTKis (n=171) as first-line of treatment was 86.5% (22.2 CR+64.3 PR), while the ORR with venetoclax +/- anti-CD20 (n=15) was 91% (45.5% CR+45.5 PR). Patients treated with CIT (n=694) had an ORR of 68.7% (28.3% CR+40.4% PR). In conclusion, in a large international study we provide real world data regarding the selection and sequencing of treatment in CLL, charting a major shift in treatment patterns before and after the introduction of novel trargeted agents and confirming their efficacy even in high-risk CLL. Disclosures Scarfo: Janssen: Honoraria, Other: Travel grants; Astra Zeneca: Honoraria; Abbvie: Honoraria. Iacoboni: BMS/Celgene, Gilead, Novartis, Janssen, Roche: Honoraria. Collado: Abbvie,: Other: pharmaceutical Company, Research Funding; Janssen: Other: Pharmaceutical Company, Research Funding. Galimberti: AbbVie, Janssen: Honoraria, Other: Travel grants; Incyte: Speakers Bureau. García-Serra: AbbVie: Other: Educational grands; Janssen: Other: Educational grants; Novartis: Other: Educational grants. Gozzetti: Janssen: Honoraria; AbbVie: Honoraria. Hatzimichael: Amgen, Roche, Genesis, Novartis, Bristol Mayer Squibb, Celgene, Pfizer: Consultancy; Abbvie, Amgen, Bristol Mayer Squibb, MSD, Gilead, Janssen Cilag, Genesis Pharma, Roche, Takeda: Honoraria. Herishanu: AbbVie: Honoraria, Research Funding; Janssen: Honoraria; Roche: Honoraria; Medison: Honoraria. Jaksic: Roche, Oktal-Pharma/Celtrion, Sandoz: Consultancy, Honoraria. Kater: Janssen, AstraZeneca: Other: Ad Board, steering committee, Research Funding; Abbvie: Honoraria, Other: Ad Board, Research Funding; BMS, Roche/Genentech: Other: Ad Board, , Research Funding; Genmab, LAVA: Other: Ad Board, Steering Committee. Kotsianidis: Astellas: Other: NONE, Research Funding, Speakers Bureau; Genesis: Consultancy, Other: NONE; Janssen Hellas: Consultancy, Other: NONE, Speakers Bureau; Bristol Hellas: Consultancy, Other: NONE, Research Funding, Speakers Bureau; Novartis Hellas: Consultancy, Other: NONE, Research Funding, Speakers Bureau; Abbvie: Consultancy, Other: NONE, Research Funding, Speakers Bureau. Kreitman: NIH: Patents & Royalties: Moxetumomab Pasudotox; Genentech: Research Funding; Teva: Research Funding; AstraZeneca/MedImmune: Research Funding; Innate: Research Funding; GSK/Novartis: Research Funding; Array BioPharma/Pfizer: Research Funding. Laribi: BeiGene: Other: Personal Fees; Jansen: Research Funding; Novartis: Other: Personal Fees, Research Funding; Astellas Phama, Inc.: Other: Personal Fees; AstraZeneca: Other: Personal Fees; Le Mans Hospital: Research Funding; Takeda: Other: Personal Fees, Research Funding; AbbVie: Other: Personal Fees, Research Funding; IQONE: Other: Personal Fees. Lopez-Garcia: Roche: Other: Speaker Honoraria, Travel and accommodation grants; Novonordisk: Other: Speaker Honoraria; Fresenius: Other: Speaker Honoraria; Celgene: Other: Speaker Honoraria; Abbvie: Other: Speaker Honoraria, Advisor, Travel and accommodation grants; Janssen: Other: Speaker Honoraria, Advisor, Travel and accommodation grants, Research Funding. Milosevic: Roche: Honoraria; Abbvie,: Honoraria; Janssen: Honoraria; Sandoz: Honoraria. Reda: Beigene: Consultancy; Astra Zeneca: Consultancy; Abbvie: Consultancy; Janssen: Consultancy. Ruchlemer: AbbVie: Consultancy, Honoraria, Research Funding. Šimkovič: Janssen, Gilead, Roche, AstraZeneca, and AbbVie: Other: consultancy fees, advisory board participation fees, travel grants, and honoraria; University Hospital Hradec Kralove: Current Employment; AbbVie: Consultancy, Current equity holder in publicly-traded company, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel, Accommodations, Expenses; AstraZeneca: Consultancy, Membership on an entity's Board of Directors or advisory committees; Janssen-Cilag: Consultancy, Honoraria, Other: Travel, Accommodations, Expenses; Merck: Current equity holder in publicly-traded company; Eli Lilly: Current equity holder in publicly-traded company; J&J: Current equity holder in publicly-traded company; Gilead: Other: Travel, Accommodations, Expenses. Špaček: AbbVie, AstraZeneca, Gilead, Janssen, and Roche: Honoraria. Tadmor: Janssen: Consultancy, Honoraria, Research Funding; AbbVie: Consultancy, Honoraria, Research Funding. Visentin: Italfarmaco and Gilead: Speakers Bureau. Vassilakopoulos: AstraZeneca: Honoraria; Amgen: Honoraria, Research Funding; Pfizer: Research Funding; Dr. Reddy's: Research Funding; Novartis: Consultancy, Honoraria; GlaxoSmithKline: Honoraria, Other: Travel; Merck: Honoraria, Research Funding; Integris: Honoraria; Roche: Consultancy, Honoraria, Other: Travel; Genesis Pharma: Consultancy, Honoraria, Other: Travel; Takeda: Consultancy, Honoraria, Other: Travel, Research Funding; AbbVie: Consultancy, Honoraria; Karyopharm: Research Funding. Vitale: Janssen: Honoraria. Yáñez: Gilead-Kite, Janssen, AbbVie, AstraZeneca, Beigene, Roche, Pfizer, Jazz, BMS, and Merck: Other: Advisory board participation fees ; Janssen, AbbVie, AstraZeneca, Gilead-Kite, Roche, Pfizer, and Merck: Speakers Bureau. Antic: AbbVie, Janssen, and Roche: Honoraria. Coscia: Janssen: Honoraria, Other, Research Funding; Gilead: Honoraria; AstraZeneca: Honoraria; AbbVie: Honoraria, Other. Cuneo: AstraZeneca: Consultancy, Speakers Bureau; Janssen: Consultancy, Speakers Bureau; Gilead: Consultancy, Speakers Bureau; AbbVie: Consultancy, Speakers Bureau. Gaidano: Beigene: Membership on an entity's Board of Directors or advisory committees; Incyte: Membership on an entity's Board of Directors or advisory committees; Janssen: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Astrazeneca: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Abbvie: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. Guièze: Janssen: Consultancy, Honoraria; Abbvie: Consultancy, Honoraria, Research Funding; Roche: Consultancy, Honoraria; Astrazeneca: Consultancy, Honoraria. Laurenti: AstraZeneca: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria, Research Funding; Roche: Honoraria, Research Funding; Gilead: Honoraria; Janssen: Consultancy, Honoraria; BeiGene: Honoraria. Murru: Abbvie: Consultancy, Honoraria, Other: travel and accommodation; Janssen: Consultancy, Honoraria. Sportoletti: AstraZeneca: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria. Tam: Beigene: Research Funding; Janssen: Research Funding; Abbvie: Research Funding; Loxo: Honoraria; Beigene: Honoraria; Janssen: Honoraria; Abbvie: Honoraria. Trněný: Amgen: Consultancy, Honoraria; Bristol-Myers Squibb: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel, Accommodations, Expenses; Gilead Sciences: Consultancy, Honoraria, Other: Travel, Accommodations, Expenses; Incyte: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel, Accommodations, Expenses; MorphoSys: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Roche: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel, Accommodations, Expenses; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel, Accommodations, Expenses; Celgene: Consultancy; 1st Faculty of Medicine, Charles University, General Hospital in Prague: Current Employment; Novartis: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Portola: Honoraria, Membership on an entity's Board of Directors or advisory committees; AstraZeneca: Honoraria; AbbVie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel, Accommodations, Expenses. Bosch Albareda: Janssen: Consultancy, Honoraria, Research Funding, Speakers Bureau; Gilead: Consultancy, Honoraria; Abbvie: Consultancy; AstraZeneca: Consultancy, Honoraria, Research Funding; Roche: Consultancy, Honoraria, Research Funding, Speakers Bureau; Takeda: Honoraria, Research Funding; Novartis: Honoraria, Research Funding; Kite: Honoraria; Sanofi: Honoraria; Lilly: Honoraria. Doubek: Janssen-Cilag, AbbVie, AstraZeneca, Amgen, Gilead, Novartis: Honoraria, Research Funding. Chatzidimitriou: Abbvie: Honoraria, Research Funding; Janssen: Honoraria, Research Funding. Ghia: AbbVie: Consultancy, Honoraria, Research Funding; Acerta/AstraZeneca: Consultancy, Honoraria, Research Funding; AstraZeneca: Consultancy, Honoraria, Research Funding; ArQule/MSD: Consultancy, Honoraria; BeiGene: Consultancy, Honoraria; Celgene/Juno/BMS: Consultancy, Honoraria; Gilead: Consultancy, Research Funding; Janssen: Consultancy, Honoraria, Research Funding; Roche: Consultancy, Honoraria; Sunesis: Research Funding. Stamatopoulos: AstraZeneca: Honoraria, Research Funding; Abbvie: Honoraria, Research Funding; Gilead: Honoraria, Research Funding; Janssen: Honoraria, Research Funding.