Dissertations / Theses on the topic 'Mapping human chromosomes'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Mapping human chromosomes.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Laval, S. H. "Molecular analysis of mammalian sex chromosomes." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302954.
Full textKedra, Darek. "Characterization of candidate disease genes from human chromosomes 11g13 and 22q /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3792-3/.
Full textBaker, Elizabeth Gay. "The mapping of human chromosomes by fluorescence in situ hybridization /." Title page, contents and summary only, 1996. http://web4.library.adelaide.edu.au/theses/09MSM/09msmb167.pdf.
Full textCopies of author's previously published articles inserted. Includes bibliographical references (leaves 122-142).
Stephens, Sarah H. "Fine mapping of the chromosome 15q13-14 schizophrenia linkage region /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2008.
Find full textTypescript. Includes bibliographical references (leaves 112-128). Free to UCD Anschutz Medical Campus. Online version available via ProQuest Digital Dissertations;
Åkesson, Eva. "Genetic mapping and association analysis in multiple sclerosis /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-174-1/.
Full textWittwer, Pia Ethena. "Physical and genetical investigation of the Xp11.3 region on the short arm of the human X-chromosome." Thesis, University of the Western Cape, 2004. http://etd.uwc.ac.za/index.php?module=etd&.
Full textSundholm, James, and n/a. "Analysis of Specific Migraine Candidate Genes Mapping to Human Chromosome 1." Griffith University. School of Health Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030829.153348.
Full textHolm, Sofia. "Molecular genetic studies of psoriasis susceptibility in 6p21.3 /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-225-X.
Full textLiu, Jian. "Deletion mapping of human 3P in major epithelial malignancies and fine localization of candidate tumor suppressor genes /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-577-8/.
Full textChristoffels, Alan. "Generation of a human gene index and its application to disease candidacy." Thesis, University of the Western Cape, 2001. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2413_1185436829.
Full textWith easy access to technology to generate expressed sequence tags (ESTs), several groups have sequenced from thousands to several thousands of ESTs. These ESTs benefit from consolidation and organization to deliver significant biological value. A number of EST projects are underway to extract maximum value from fragmented EST resources by constructing gene indices, where all transcripts are partitioned into index classes such that transcripts are put into the same index class if they represent the same gene. Therefore a gene index should ideally represent a non-redundant set of transcripts. Indeed, most gene indices aim to reconstruct the gene complement of a genome and their technological developments are directed at achieving this goal. The South African National Bioinformatics Institute (SANBI), on the other hand, embarked on the development of the sequence alignment and consensus knowledgebase (STACK) database that focused on the detection and visualisation of transcript variation in the context of developmental and pathological states, using all publicly available ESTs. Preliminary work on the STACK project employed an approach of partitioning the EST data into arbitrarily chosen tissue categories as a means of reducing the EST sequences to manageable sizes for subsequent processing. The tissue partitioning provided the template material for developing error-checking tools to analyse the information embedded in the error-laden EST sequences. However, tissue partitioning increases redundancy in the sequence data because one gene can be expressed in multiple tissues, with the result that multiple tissue partitioned transcripts will correspond to the same gene.
Therefore, the sequence data represented by each tissue category had to be merged in order to obtain a comprehensive view of expressed transcript variation across all available tissues. The need to consolidate all EST information provided the impetus for developing a STACK human gene index, also referred to as a whole-body index. In this dissertation, I report on the development of a STACK human gene index represented by consensus transcripts where all constituent ESTs sample single or multiple tissues in order to provide the correct development and pathological context for investigating sequence variation. Furthermore, the availability of a human gene index is assessed as a diseasecandidate gene discovery resource. A feasible approach to construction of a whole-body index required the ability to process error-prone EST data in excess of one million sequences (1,198,607 ESTs as of December 1998). In the absence of new clustering algorithms, at that time, we successfully ported D2_CLUSTER, an EST clustering algorithm, to the high performance shared multiprocessor machine, Origin2000. Improvements to the parallelised version of D2_CLUSTER included: (i) ability to cluster sequences on as many as 126 processors. For example, 462000 ESTs were clustered in 31 hours on 126 R10000 MHz processors, Origin2000. (ii) enhanced memory management that allowed for clustering of mRNA sequences as long as 83000 base pairs. (iii) ability to have the input sequence data accessible to all processors, allowing rapid access to the sequences. (iv) a restart module that allowed a job to be restarted if it was interrupted. The successful enhancements to the parallelised version of D2_CLUSTER, as listed above, allowed for the processing of EST datasets in excess of 1 million sequences. An hierarchical approach was adopted where 1,198,607 million ESTs from GenBank release 110 (October 1998) were partitioned into "
tissue bins"
and each tissue bin was processed through a pipeline that included masking for contaminants, clustering, assembly, assembly analysis and consensus generation. A total of 478,707 consensus transcripts were generated for all the tissue categories and these sequences served as the input data for the generation of the wholebody index sequences. The clustering of all tissue-derived consensus transcripts was followed by the collapse of each consensus sequence to its individual ESTs prior to assembly and whole-body index consensus sequence generation. The hierarchical approach demonstrated a consolidation of the input EST data from 1,198607 ESTs to 69,158 multi-sequence clusters and 162,439 singletons (or individual ESTs). Chromosomal locations were added to 25,793 whole-body index sequences through assignment of genetic markers such as radiation hybrid markers and gé
né
thon markers. The whole-body index sequences were made available to the research community through a sequence-based search engine (http://ziggy.sanbi.ac.za/~alan/researchINDEX.html).
Holm, Pernilla. "Genetic studies of susceptibility to diabetes mellitus with emphasis on type 1 diabetes /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-527-1/.
Full textKholodnyuk, Irina. "A microcell hybrid based elimination test to identify human chromosome 3 regions that antagonize tumor growth /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-581-6/.
Full textKöhn, Linda. "Genetic mapping of retinal degenerations in Northern Sweden." Umeå : Umeå university, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-27004.
Full textBrinkman-Mills, Polly. "Transcriptional mapping in human chromosome 22q11.2." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0015/MQ47011.pdf.
Full textApostolou, Sinoula. "Physical mapping of human chromosome 16." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09pha645.pdf.
Full textCreavin, Treasa Agnes Della Geraldine. "Transcriptional mapping of human chromosome 16p12.3-p12.2." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321891.
Full textHinkley, Craig S. (Craig Steven). "Gene Dosage Study on Human Chromosome 22." Thesis, North Texas State University, 1986. https://digital.library.unt.edu/ark:/67531/metadc500617/.
Full textJanunger, Tomas. "The genetic contribution to stroke in northern Sweden." Doctoral thesis, Umeå : Umeå university, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-31929.
Full textWixon, Joanne. "Physical and transcriptional mapping in human chromosome band 6p23." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363758.
Full textFratini, Antonio. "Fragile sites on human chromosome 16 : a linkage analysis study /." Title page, table of contents and summary only, 1988. http://web4.library.adelaide.edu.au/theses/09PH/09phf844.pdf.
Full textMaslen, G. Ll. "Molecular analysis of the mammalian X-chromosome." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260723.
Full textPriestley, Matthew David. "Detailed mapping of a congenital heart disease gene in chromosome 3p25." Thesis, University of Birmingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270058.
Full textWong, Chi Cheung Andrew. "Transcriptional mapping in a terminal microdeletion of human chromosome 22q." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ34859.pdf.
Full textHowell, Gareth Rhys. "Physical, transcriptional and comparative mapping on the human X chromosome." Thesis, Open University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394787.
Full textDaly, Maria Catherine. "Chromosome 3 deletion mapping in human small cell lung cancer." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304095.
Full textBryant, Stephen Paul. "Pedigree analysis and gene mapping." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390811.
Full textStafford, Amanda Newland. "Physical mapping within human chromosome 11q12-q13 including the atopy locus." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239248.
Full textWilliams, Gareth Owen. "Mapping studies of the centromeric region of the human Y chromosome." Thesis, University of Oxford, 1998. http://ora.ox.ac.uk/objects/uuid:c471a22f-e52b-452a-8714-bfcd9610da44.
Full textGreenham, Jaimie Alexanda. "The identification and integration of transcripts mapping to human chromosome 16p12.2." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286479.
Full textGillett, Godfrey Tregelles. "Use of irradiation hybrids in gene mapping on human chromosome II." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322187.
Full textGroet, Jurgen. "Physical mapping and identification of novel genes in human chromosome 21q11." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312003.
Full textEvans, Wayne. "Physical and transcriptional mapping of Xq22.3 on the human X chromosome." Thesis, King's College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322079.
Full textPlummer, Alisa C. "Transcriptional mapping within a 1.7 megabase region of human chromosome 17Q21." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 1999. http://digitalcommons.auctr.edu/dissertations/3019.
Full textRebello, Manuel Teixeira. "Genetic and physical mapping of the short arm of human chromosome 9." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267982.
Full textHassock, Sheila Ruth. "Physical and transcriptional mapping in the distal Xq28 region of the human X chromosome." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312021.
Full textLam, Tai-wai. "Structural organization, transcriptional regulation and chromosomal localization of the human secretin gene." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23316652.
Full textHammarsund, Marianne. "Genetic changes in lymphoid leukemia /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-628-5841-6/.
Full textShutler, Gary G. "Genetic and physical mapping of the myotonic dystrophy locus on human chromosome 19q13.3." Thesis, University of Ottawa (Canada), 1993. http://hdl.handle.net/10393/6793.
Full textMensah, Afua Adjeiwaa. "Mapping human chromosome 21 gene dose effects on tumour suppression and neural differentiation." Thesis, Queen Mary, University of London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414704.
Full textKirchgessner, Cordula U. "The Human Synapsin I Gene: Linkage Mapping on the X Chromosome: A Dissertation." eScholarship@UMMS, 1991. http://escholarship.umassmed.edu/gsbs_diss/241.
Full textLioumi, Maria. "Physical mapping of human chromosomal band Iq21 and characterisation of new genes." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392438.
Full text林大偉 and Tai-wai Lam. "Structural organization, transcriptional regulation and chromosomal localization of the human secretin gene." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31224593.
Full textLapsys, Naras Mykolas. "The FRA 16B locus : long range restriction mapping of 16q13-16q22.1 /." Title page, table of contents and summary only, 1993. http://web4.library.adelaide.edu.au/theses/09PH/09phl317.pdf.
Full textFlomen, Rachel Helena. "Gene analysis and physical mapping in the Xq27.3-Xq28 region of the human X chromosome." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336342.
Full textLowe, Yvonne. "Linkage mapping of a familial MeÌnieÌ€re disease locus to a human chromosome 14q21.2-q21.3." Thesis, University of Glasgow, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443282.
Full textHornigold, James Nicholls Andrew. "Physical mapping using Hinfl cosmid fingerprinting : its application to the human Y chromosome and to 9q34." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300167.
Full textPhilippe, Christophe. "Cartographie physique du chromosome X humain : 1) contribution à la cartographie physique de la région q13-q22 du chromosome X humain : 2) analyse de deux cas de pathologies récessives liées à l'X chez des femmes porteuses de translocation (X ; Autosome) équilibrées." Vandoeuvre-les-Nancy, INPL, 1994. http://docnum.univ-lorraine.fr/public/INPL_T_1994_PHILIPPE_C.pdf.
Full textFootz, Tim. "Mapping of the region of mouse chromosome 6 homologous to the human cat eye syndrome critical region." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0020/MQ47030.pdf.
Full textLeversha, Margaret Anne. "Cytological estimations of molecular genetic difference : applications and implications of fluorescence in situ hybridisation mapping in the long arm of human chromosome 9." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337902.
Full textBrown, G. M. "Genetic mapping on human chromosome 9 by analysis of meiotic recombination in single sperm using polymorphic microsatellite markers." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596982.
Full text