Journal articles: 'Mappe mentali'

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Arzenton, Andrea, and Cinzia Nicolais. "Nuove geografie urbane. Le mappe dei rider riscrivono la città." TERRITORIO, no. 100 (November 2022): 92–103. http://dx.doi.org/10.3280/tr2022-100011.

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Alla luce di una cartografia inadeguata a rappresentare la complessità della città contemporanea, con il ricco mosaico di pratiche generato dalle sue molteplici popolazioni, la ricerca qui presentata intende contribuire a costruire una diversa immagine urbana che possa descrivere la nascita e l'evoluzione di nuove dinamiche di vita e di lavoro, legate in particolare alla comparsa della popolazione dei rider. Lavoratori nomadi della città, i rider sono portatori di un punto di vista innovativo, che viene indagato attraverso un metodo volto a far emergere dalle mappe mentali disegnate dagli stessi rider la geografia generata dal loro movimento. Da qui si sviluppa un progetto di infrastrutturazione leggera della città, a servizio del lavoro dei rider e di tutti i cittadini. Parole chiave: rider; mappe mentali; geografie

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Mastrofini, Enrico. "Project management template / Project management facile con le mappe mentali." PROJECT MANAGER (IL), no. 16 (December 2013): 47. http://dx.doi.org/10.3280/pm2013-016016.

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Sanders, Christina. "«Mental mapping» the EC. Perceptions of students in EC countries." Mappemonde 23, no. 3 (1991): 16–18. http://dx.doi.org/10.3406/mappe.1991.973.

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Andre, Yves. "Cartes mentales pour un territoire : à propos du Bassin de Genève." Mappemonde 13, no. 1 (1989): 12–15. http://dx.doi.org/10.3406/mappe.1989.2481.

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Yakeley, Jessica, Richard Taylor, and Angus Cameron. "MAPPA and mental health — 10 years of controversy." Psychiatrist 36, no. 6 (June 2012): 201–4. http://dx.doi.org/10.1192/pb.bp.111.037960.

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SummaryMultiagency public protection arrangements (MAPPAs) were established in England and Wales 10 years ago to oversee statutory arrangements for public protection by the identification, assessment and management of high-risk offenders. This article reviews MAPPAs' relationship with mental health services over the past decade. Despite areas of progress in the management of mentally ill offenders, inconsistent practice persists regarding issues of confidentiality and information-sharing between agencies, which calls for clearer and more consistent guidance from the Royal College of Psychiatrists, the Ministry of Justice and the Department of Health.

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Cheek, Colleen, Theresa Fleming, Mathijs FG Lucassen, Heather Bridgman, Karolina Stasiak, Matthew Shepherd, and Peter Orpin. "Integrating Health Behavior Theory and Design Elements in Serious Games." JMIR Mental Health 2, no. 2 (April 21, 2015): e11. http://dx.doi.org/10.2196/mental.4133.

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Background Internet interventions for improving health and well-being have the potential to reach many people and fill gaps in service provision. Serious gaming interfaces provide opportunities to optimize user adherence and impact. Health interventions based in theory and evidence and tailored to psychological constructs have been found to be more effective to promote behavior change. Defining the design elements which engage users and help them to meet their goals can contribute to better informed serious games. Objective To elucidate design elements important in SPARX, a serious game for adolescents with depression, from a user-centered perspective. Methods We proposed a model based on an established theory of health behavior change and practical features of serious game design to organize ideas and rationale. We analyzed data from 5 studies comprising a total of 22 focus groups and 66 semistructured interviews conducted with youth and families in New Zealand and Australia who had viewed or used SPARX. User perceptions of the game were applied to this framework. Results A coherent framework was established using the three constructs of self-determination theory (SDT), autonomy, competence, and relatedness, to organize user perceptions and design elements within four areas important in design: computer game, accessibility, working alliance, and learning in immersion. User perceptions mapped well to the framework, which may assist developers in understanding the context of user needs. By mapping these elements against the constructs of SDT, we were able to propose a sound theoretical base for the model. Conclusions This study’s method allowed for the articulation of design elements in a serious game from a user-centered perspective within a coherent overarching framework. The framework can be used to deliberately incorporate serious game design elements that support a user’s sense of autonomy, competence, and relatedness, key constructs which have been found to mediate motivation at all stages of the change process. The resulting model introduces promising avenues for future exploration. Involving users in program design remains an imperative if serious games are to be fit for purpose.

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Behrmann, Marlene. "The Mind's Eye Mapped Onto the Brain's Matter." Current Directions in Psychological Science 9, no. 2 (April 2000): 50–54. http://dx.doi.org/10.1111/1467-8721.00059.

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Research on visual mental imagery has been fueled recently by the development of new behavioral and neuroscientific techniques. This review focuses on two major topics in light of these developments. The first concerns the extent to which visual mental imagery and visual perception share common psychological and neural mechanisms; although the research findings largely support convergence between these two processes, there are data that qualify the degree of overlap between them. The second issue involves the neural substrate mediating the process of imagery generation. The data suggest a slight left-hemisphere advantage for this process, although there is considerable variability across and within subjects. There also remain many unanswered questions in this field, including what the relationship is between imagery and working memory and what representational differences, if any, exist between imagery and perception.

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Grodzinsky, Yosef, Isabelle Deschamps, Peter Pieperhoff, Francesca Iannilli, Galit Agmon, Yonatan Loewenstein, and Katrin Amunts. "Logical negation mapped onto the brain." Brain Structure and Function 225, no. 1 (November 4, 2019): 19–31. http://dx.doi.org/10.1007/s00429-019-01975-w.

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Abstract High-level cognitive capacities that serve communication, reasoning, and calculation are essential for finding our way in the world. But whether and to what extent these complex behaviors share the same neuronal substrate are still unresolved questions. The present study separated the aspects of logic from language and numerosity—mental faculties whose distinctness has been debated for centuries—and identified a new cytoarchitectonic area as correlate for an operation involving logical negation. A novel experimental paradigm that was implemented here in an RT/fMRI study showed a single cluster of activity that pertains to logical negation. It was distinct from clusters that were activated by numerical comparison and from the traditional language regions. The localization of this cluster was described by a newly identified cytoarchitectonic area in the left anterior insula, ventro-medial to Broca’s region. We provide evidence for the congruence between the histologically and functionally defined regions on multiple measures. Its position in the left anterior insula suggests that it functions as a mediator between language and reasoning areas.

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Zappoli, R., A. Versari, G. Arnetoli, M. Paganini, A. Battaglia, G. C. Muscas, and C. Nencioni. "Bit-mapped cognitive event-related potentials (CNV activity) in primary mental deterioration." Electroencephalography and Clinical Neurophysiology 75 (January 1990): S164. http://dx.doi.org/10.1016/0013-4694(90)92318-q.

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VOYCE, M. A., J. N. MONTGOMERY, L. CROME, J. BOWMAN, and J. T. IRELAND. "MAPLE SYRUP URINE DISEASE." Journal of Intellectual Disability Research 11, no. 4 (June 28, 2008): 231–38. http://dx.doi.org/10.1111/j.1365-2788.1967.tb00224.x.

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Wittwer, Bärbel, Renate Kircheisen, Jutta Leutelt, Ulrike Orth, and Andreas Gal. "New X-linked mental retardation syndrome with the gene mapped tentatively in Xp22.3." American Journal of Medical Genetics 64, no. 1 (July 12, 1996): 42–49. http://dx.doi.org/10.1002/(sici)1096-8628(19960712)64:1<42::aid-ajmg6>3.0.co;2-t.

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Lovell, Karina, and David Richards. "MULTIPLE ACCESS POINTS AND LEVELS OF ENTRY (MAPLE): ENSURING CHOICE, ACCESSIBILITY AND EQUITY FOR CBT SERVICES." Behavioural and Cognitive Psychotherapy 28, no. 4 (October 2000): 379–91. http://dx.doi.org/10.1017/s1352465800004070.

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Mental health problems contribute 23% to the global burden of disease in developed countries (WHO, 1999). In the U.K., recent legislation attempts to address this by modernizing mental health services so that they provide evidence based, accessible and non-discriminatory services for both serious and common mental health problems. Cognitive behaviour therapy (CBT) has a robust evidence base that fits very well with the thrust of policy. However, CBT's delivery systems are rooted in traditional service models, which pay little attention to the growing evidence base for brief and single-strand treatments over complex or multi-strand interventions. Services characterized by 9-5 working, hourly appointments and face-to-face therapy disenfranchise the majority of people who would benefit from CBT. In this paper we argue that the evidence exists for service protocols that promote equity, accessibility and choice and that CBT services should be organized around multiple levels of entry and service delivery rather than the more usual secondary care referral systems.

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Kuboszek, Artur. "Work ergonomics in a service enterprise – case study." Multidisciplinary Aspects of Production Engineering 2, no. 1 (September 1, 2019): 274–82. http://dx.doi.org/10.2478/mape-2019-0027.

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Abstract The article presents the results of research carried out as part of a project aimed at integrated ergonomic diagnosis of the work environment in terms of improvement of technical and psychosocial conditions. The studies carried out so far included small and medium-sized enterprises located in the Śląskie (Silesian) Voivodeship. The research included manual work as well as administrative (mental) work. Ergonomic diagnosis was carried out by direct observation of employees at the workplace using tools such as the Ergonomic Control Test CET II and the Dortmund List. This article presents the results of ergonomic analysis at the hairdresser workplace.

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Nowacki, Krzysztof, Sandra Grabowska, and Teresa Lis. "The Impact of Remote Working During the COVID-19 Epidemic on Employee Well-being." Multidisciplinary Aspects of Production Engineering 4, no. 1 (September 1, 2021): 245–54. http://dx.doi.org/10.2478/mape-2021-0022.

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Abstract The aim of the research was to answer the question whether the remote work imposed on workers during the COVID-19 epidemic has an impact on their well-being, and if so, how. The research material consisted of the results of a survey conducted among the employees referred to remote work in connection with the announced state of the epidemic in Poland. The research was conducted in the period from July 31 to August 19, 2020. The research was conducted using a questionnaire method, the study was attended by 199 respondents. A survey questionnaire was used in the study and the results obtained were statistically processed. The research carried out allowed us to obtain the results of the self-assessment of employees referred to work in the homme-office in terms of their mental well-being and physical well-being.

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Guo, Xiangming, Huangxuan Shen, Xueshan Xiao, Qilin Dai, Shiqiang Li, Xiaoyun Jia, J. Fielding Hejtmancik, and Qingjiong Zhang. "Cataracts, ataxia, short stature, and mental retardation in a Chinese family mapped to Xpter-q13.1." Journal of Human Genetics 51, no. 8 (July 11, 2006): 695–700. http://dx.doi.org/10.1007/s10038-006-0009-1.

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Macdonald, Jacqui A., Lauren M. Francis, Helen Skouteris, George J. Youssef, Liam G. Graeme, Joanne Williams, Richard J. Fletcher, et al. "Cohort profile: the Men and Parenting Pathways (MAPP) Study: a longitudinal Australian cohort study of men’s mental health and well-being at the normative age for first-time fatherhood." BMJ Open 11, no. 7 (July 2021): e047909. http://dx.doi.org/10.1136/bmjopen-2020-047909.

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PurposeThe Men and Parenting Pathways (MAPP) Study is a prospective investigation of men’s mental health and well-being across the normative age for transitioning to fatherhood. This includes trajectories and outcomes for men who do and do not become fathers across five annual waves of the study.ParticipantsAustralian resident, English-speaking men aged 28–32 years at baseline were eligible. Recruitment was over a 2-year period (2015–2017) via social and traditional media and through engagement with study partners. Eight hundred and eighteen eligible men consented to participate. Of these, 664 men completed the first online survey of whom 608 consented to ongoing participation. Of the ongoing sample, 83% have participated in at least two of the first three annual online surveys.Findings to dateThree waves of data collection are complete. The first longitudinal analysis of MAPP data, published in 2020, identified five profiles that characterise men’s patterns of depressive symptom severity and presentations of anger. Profiles indicating pronounced anger and depressive symptoms were associated with fathers’ lack of perceived social support, and problems with coparenting and bonding with infants. In a second study, MAPP data were combined with three other Australian cohorts in a meta-analysis of associations between fathers’ self-reported sleep problems up to 3 years postpartum and symptoms of depression, anxiety and stress. Adjusted meta-analytic associations between paternal sleep and mental health risk ranged from 0.25 to 0.37.Future plansMAPP is an ongoing cohort study. Waves 4 and 5 data will be ready for analyses at the end of 2021. Future investigations will include crossed-lagged and trajectory analyses that assess inter-relatedness and changing social networks, mental health, work and family life. A nested study of COVID-19 pandemic-related mental health and coping will add two further waves of data collection in a subsample of MAPP participants.

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Sweet, Daryl, Richard Byng, Martin Webber, Doyo Gragn Enki, Ian Porter, John Larsen, Peter Huxley, and Vanessa Pinfold. "Personal well-being networks, social capital and severe mental illness: exploratory study." British Journal of Psychiatry 212, no. 5 (April 6, 2018): 308–17. http://dx.doi.org/10.1192/bjp.bp.117.203950.

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BackgroundConnectedness is a central dimension of personal recovery from severe mental illness (SMI). Research reports that people with SMI have lower social capital and poorer-quality social networks compared to the general population.AimsTo identify personal well-being network (PWN) types and explore additional insights from mapping connections to places and activities alongside social ties.MethodWe carried out 150 interviews with individuals with SMI and mapped social ties, places and activities and their impact on well-being. PWN types were developed using social network analysis and hierarchical k-means clustering of this data.ResultsThree PWN types were identified: formal and sparse; family and stable; and diverse and active. Well-being and social capital varied within and among types. Place and activity data indicated important contextual differences within social connections that were not found by mapping social networks alone.ConclusionsPlace locations and meaningful activities are important aspects of people's social worlds. Mapped alongside social networks, PWNs have important implications for person-centred recovery approaches through providing a broader understanding of individual's lives and resources.Declaration of interestNone.

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Zacks, Jeffrey M. "Neuroimaging Studies of Mental Rotation: A Meta-analysis and Review." Journal of Cognitive Neuroscience 20, no. 1 (January 2008): 1–19. http://dx.doi.org/10.1162/jocn.2008.20013.

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Mental rotation is a hypothesized imagery process that has inspired controversy regarding the substrate of human spatial reasoning. Two central questions about mental rotation remain: Does mental rotation depend on analog spatial representations, and does mental rotation depend on motor simulation? A review and meta-analysis of neuroimaging studies help answer these questions. Mental rotation is accompanied by increased activity in the intraparietal sulcus and adjacent regions. These areas contain spatially mapped representations, and activity in these areas is modulated by parametric manipulations of mental rotation tasks, supporting the view that mental rotation depends on analog representations. Mental rotation also is accompanied by activity in the medial superior precentral cortex, particularly under conditions that favor motor simulation, supporting the view that mental rotation depends on motor simulation in some situations. The relationship between mental rotation and motor simulation can be understood in terms of how these two processes update spatial reference frames.

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Lloyd-Evans, Brynmor, Danielle Lamb, Joseph Barnby, Michelle Eskinazi, Amelia Turner, and Sonia Johnson. "Mental health crisis resolution teams and crisis care systems in England: a national survey." BJPsych Bulletin 42, no. 4 (May 24, 2018): 146–51. http://dx.doi.org/10.1192/bjb.2018.19.

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Aims and methodA national survey investigated the implementation of mental health crisis resolution teams (CRTs) in England. CRTs were mapped and team managers completed an online survey.ResultsNinety-five per cent of mapped CRTs (n = 233) completed the survey. Few CRTs adhered fully to national policy guidelines. CRT implementation and local acute care system contexts varied substantially. Access to CRTs for working-age adults appears to have improved, compared with a similar survey in 2012, despite no evidence of higher staffing levels. Specialist CRTs for children and for older adults with dementia have been implemented in some areas but are uncommon.Clinical implicationsA national mandate and policy guidelines have been insufficient to implement CRTs fully as planned. Programmes to support adherence to the CRT model and CRT service improvement are required. Clearer policy guidance is needed on requirements for crisis care for young people and older adults.Declaration of interestNone.

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Bondy, Madeleine, and Donald C. Cole. "Striving for Balance and Resilience: Ontario Farmers’ Perceptions of Mental Health." Canadian Journal of Community Mental Health 39, no. 1 (May 1, 2020): 101–18. http://dx.doi.org/10.7870/cjcmh-2020-007.

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Farmers face multiple stressors and are becoming alert to mental health, yet their views are underresearched. We conducted, recorded, and thematically analyzed 16 semi-structured interviews with Ontario small-holder farmers recruited through county farm organizations. A subset mapped stress effects on their health. Farmers believed their health was fundamental to their farms’ viability and they approached challenges to their health and mental health similarly to how they would approach challenges to their farm. Health was a balancing act amidst stressors; good stress challenging them, and bad stress occasionally overwhelming them. Poor mental health was a barrier, while good mental health was essential for resilience. Multiple opportunities exist to work with farmers, farm organizations, and their rural communities to better support farmers striving for balance and resilience in their mental health.

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SEEGMILLER, J. E., and R. G. WESTALL. "THE ENZYME DEFECT IN MAPLE SYRUP URINE DISEASE." Journal of Intellectual Disability Research 11, no. 4 (June 28, 2008): 288–94. http://dx.doi.org/10.1111/j.1365-2788.1967.tb00233.x.

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Raynaud, Martine, Nathalie Ronce, Anne-Dominique Ayrault, Christine Francannet, Georges Malpuech, and Claude Moraine. "X-linked mental retardation with isolated growth hormone deficiency is mapped to Xq22-Xq27.2 in one family." American Journal of Medical Genetics 76, no. 3 (March 19, 1998): 255–61. http://dx.doi.org/10.1002/(sici)1096-8628(19980319)76:3<255::aid-ajmg10>3.0.co;2-g.

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Zhang, Xiyu, Qiji Liu, Bingxi Chen, Chenhong Guo, Jiangxia Li, Guimin Gao, Yishou Guo, and Yaoqin Gong. "A locus for nonspecific X-linked mental retardation mapped to a 22.3 cM region of Xp11.3-q22.3." American Journal of Medical Genetics 129A, no. 3 (2004): 286–89. http://dx.doi.org/10.1002/ajmg.a.30121.

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Marino, Maria. "Falcone M., La mappa degli stati mentali. Una guida all'inquadramento clinico del caso complesso in psicoterapia cognitiva, FrancoAngeli, Milano, 2020." QUADERNI DI PSICOTERAPIA COGNITIVA, no. 47 (February 2021): 164–66. http://dx.doi.org/10.3280/qpc47-2020oa11212.

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Michélsen, Hans, Ulla Sebrant, and Abbe Schulman. "Intervention to Prevent Mental Ill-Health Among Health Care Workers." Nordic Journal of Working Life Studies 4, no. 2 (May 1, 2014): 117. http://dx.doi.org/10.19154/njwls.v4i2.3867.

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Psychological strain in working life is gaining ever more attention. Health care workers are often under extreme emotional stress, which can become so overwhelming that they show signs of mental ill-health. This project aimed to develop a model for sustainable psychological support within a hospital clinic to prevent mental ill-health among employees. Mental strains at work and mental ill-health among clinic employees were mapped out, after which interventions for psychological support were designed in collaboration with employees. The interventions were conducted over one year and evaluated. Throughout the process the clinic received continuous feedback. Both questionnaires and interviews were used. The results of identifying mental strains and conducting interventions showed that employees experienced mental strain at work and perceived a need for support. Intervention evaluations showed that the project provided support, new insights, and an increased acceptance for long-term prevention of mental strain. Quantitative and qualitative methodologies supported the results. The conclusion was that increased legitimacy for mental strain at work and continuous feedback between clinic management and employees, as well as organizational circumstances are important factors when developing long-term intervention programs with various forms of psychological support.

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Banandur, Pradeep S. "Factors affecting Beneficiary Attendance in a Community Youth Mental Health Promotion Programme (Yuva Spandana) in Karnataka, India." Indian Journal of Youth & Adolescent Health 08, no. 02 (June 26, 2021): 8–17. http://dx.doi.org/10.24321/2349.2880.202107.

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Background: Yuva Spandana is a unique community-based Youth Mental Health Promotion programme implemented to provide guidance and counselling services to youth having any issues through Yuva Spandana Kendras (YSKs) acorss Karnataka. We assessed the factors affecting beneficiary attendance to YSKs across Karnataka. Methods: A conceptual framework was developed to understand the factors affecting beneficiary attendance through stakeholder consultation. First-time beneficiaries attending guidance centres between 1st January 2017 and 31st December 2018 across 30 districts of Karnataka were considered as study subjects. Requisite data were drawn from the computerised management information system (CMIS) specifically developed for the programme. Multivariate linear regression was performed with factors affecting beneficiary attendance as the outcome and a host of hypothesised exposures. Results: For every sensitization programme where > 1 issue was addressed, the beneficiary attendance increased by 84%. Reaching out to parent beneficiaries through sensitization programmes and referring clients to resource mapped organisations significantly increased beneficiary attendance at YSK by 79% and 81% respectively. For every percentage increase in reminder calls to beneficiaries who sought support following a sensitization programme, beneficiary attendance increased by 2.18 times. Availability of internet connectivity at these guidance centres in 2017 increased beneficiary attendance by 18 times. Conclusions: This study provides important inputs towards increasing beneficiary attendance at large scale youth mental health promotion programmes in India.

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Stahl, Stephen M. "Deconstructing violence as a medical syndrome: mapping psychotic, impulsive, and predatory subtypes to malfunctioning brain circuits." CNS Spectrums 19, no. 5 (October 2014): 357–65. http://dx.doi.org/10.1017/s1092852914000522.

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ISSUE:Violence is a major management issue for forensic mental health systems. Violence can be approached as a medical syndrome and deconstructed into psychotic, impulsive, and predatory subtypes, which are hypothetically mapped onto corresponding malfunctioning brain circuits. Rational management of violence balances treatment with security, while targeting each subtype of violence with approaches unique to the psychotic, impulsive, and predatory forms of violence.

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Conway, Christopher C., Robert D. Latzman, and Robert F. Krueger. "A Meta-Structural Model of Common Clinical Disorder and Personality Disorder Symptoms." Journal of Personality Disorders 34, no. 1 (February 2020): 88–106. http://dx.doi.org/10.1521/pedi_2019_33_383.

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A large and consistent research literature demonstrates the superiority of dimensional models of mental disorder. Factor analytic research has mapped the latent dimensions underlying separate sets of mental disorders (e.g., emotional disorders), but a common framework—unencumbered by arbitrary historical boundaries between disorder groups—requires additional research. Using empirically derived measures of three key domains of psychopathological variation, the overarching goal of the current study was to explicate dimensions connecting internalizing, externalizing, and personality disorders. Participants included 1,144 racially diverse undergraduates. Exploratory structural equation modeling analyses revealed seven latent dimensions: core internalizing, core externalizing, antagonism, impulsivity, dutifulness, detachment, and suspiciousness. This meta-structure reflects a more comprehensive model of the architecture of mental disorders than accounts derived from less inclusive assessment batteries. Future empirical work is needed to evaluate the utility of this structural model in etiological research, assessment, and treatment arenas.

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Chudley, Albert E., D. C. Tackels, Herbert A. Lubs, J. Fernando Arena, Wendi P. Stoeber, Sylvia Kovnats, Roger E. Stevenson, and Charles E. Schwartz. "X-linked mental retardation syndrome with seizures, hypogammaglobulinemia, and progressive gait disturbance is regionally mapped between Xq21.33 and Xq23." American Journal of Medical Genetics 85, no. 3 (July 30, 1999): 255–62. http://dx.doi.org/10.1002/(sici)1096-8628(19990730)85:3<255::aid-ajmg14>3.0.co;2-z.

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Roche, Charlotte, Abigail Fisher, Daisy Fancourt, and Alexandra Burton. "Exploring Barriers and Facilitators to Physical Activity during the COVID-19 Pandemic: A Qualitative Study." International Journal of Environmental Research and Public Health 19, no. 15 (July 27, 2022): 9169. http://dx.doi.org/10.3390/ijerph19159169.

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Quantitative data show that physical activity (PA) reduced during the COVID-19 pandemic, with differential impacts across demographic groups. Qualitative research is limited; thus, this study aimed to understand barriers and facilitators to PA during the pandemic, focusing on groups more likely to have been affected by restrictions, and to map these onto the capability, opportunity, motivation model of behaviour (COM-B). One-to-one interviews were conducted with younger (aged 18–24) and older adults (aged 70+), those with long-term physical or mental health conditions, and parents of young children. Themes were identified using reflexive thematic analysis and were mapped onto COM-B domains. A total of 116 participants contributed (aged 18–93, 61% female, 71% White British). Key themes were the importance of the outdoor environment, impact of COVID-19 restrictions, fear of contracting COVID-19, and level of engagement with home exercise. Caring responsibilities and conflicting priorities were a barrier. PA as a method of socialising, establishing new routines, and the importance of PA for protecting mental health were motivators. Most themes mapped onto the physical opportunity (environmental factors) and reflective motivation (evaluations/plans) COM-B domains. Future interventions should target these domains during pandemics (e.g., adapting PA guidance depending on location and giving education on the health benefits of PA).

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Mulraney, Melissa, Harriet Hiscock, Emma Sciberras, David Coghill, and Michael Sawyer. "Mental health difficulties across childhood and mental health service use: findings from a longitudinal population-based study." British Journal of Psychiatry 217, no. 1 (February 27, 2019): 364–69. http://dx.doi.org/10.1192/bjp.2019.32.

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BackgroundOver the past 20 years the prevalence of child and adolescent mental disorders in high-income countries has not changed despite increased investment in mental health services. Insufficient contact with mental health services may be a contributing factor; however, it is not known what proportion of children have sufficient contact with health professionals to allow delivery of treatment meeting minimal clinical practice guidelines, or how long children experience symptoms prior to receiving treatment.AimsTo investigate the level of mental healthcare received by Australian children from age 4 years to 14 years.MethodTrajectories of mental health symptoms were mapped using the Strengths and Difficulties Questionnaire. Health professional attendances and psychotropic medications dispensed were identified from linked national Medicare Benefits Schedule (MBS) and Pharmaceutical Benefits Scheme records.ResultsFour trajectories of mental health symptoms were identified (low, high-decreasing, moderate-increasing and high-increasing). Most children with mental health symptoms had few MBS mental health attendances, and only a minority received care meeting study criteria for minimally adequate treatment. Children in the high-increasing and moderate-increasing trajectories were more likely to access care, yet there was no evidence of improvement in symptoms.ConclusionsIt is important that children and adolescents with mental health problems receive treatment that meets minimal practice guidelines. Further research is needed to identify the quality of care currently provided to children with mental health difficulties and how clinicians can be best funded and supported to provide care meeting minimal practice guidelines.Declaration of interestsNone.

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Newson, Jennifer Jane, Vladyslav Pastukh, and Tara C. Thiagarajan. "Assessment of Population Well-being With the Mental Health Quotient: Validation Study." JMIR Mental Health 9, no. 4 (April 20, 2022): e34105. http://dx.doi.org/10.2196/34105.

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Background The Mental Health Quotient (MHQ) is an anonymous web-based assessment of mental health and well-being that comprehensively covers symptoms across 10 major psychiatric disorders, as well as positive elements of mental function. It uses a novel life impact scale and provides a score to the individual that places them on a spectrum from Distressed to Thriving along with a personal report that offers self-care recommendations. Since April 2020, the MHQ has been freely deployed as part of the Mental Health Million Project. Objective This paper demonstrates the reliability and validity of the MHQ, including the construct validity of the life impact scale, sample and test-retest reliability of the assessment, and criterion validation of the MHQ with respect to clinical burden and productivity loss. Methods Data were taken from the Mental Health Million open-access database (N=179,238) and included responses from English-speaking adults (aged≥18 years) from the United States, Canada, the United Kingdom, Ireland, Australia, New Zealand, South Africa, Singapore, India, and Nigeria collected during 2021. To assess sample reliability, random demographically matched samples (each 11,033/179,238, 6.16%) were compared within the same 6-month period. Test-retest reliability was determined using the subset of individuals who had taken the assessment twice ≥3 days apart (1907/179,238, 1.06%). To assess the construct validity of the life impact scale, additional questions were asked about the frequency and severity of an example symptom (feelings of sadness, distress, or hopelessness; 4247/179,238, 2.37%). To assess criterion validity, elements rated as having a highly negative life impact by a respondent (equivalent to experiencing the symptom ≥5 days a week) were mapped to clinical diagnostic criteria to calculate the clinical burden (174,618/179,238, 97.42%). In addition, MHQ scores were compared with the number of workdays missed or with reduced productivity in the past month (7625/179,238, 4.25%). Results Distinct samples collected during the same period had indistinguishable MHQ distributions and MHQ scores were correlated with r=0.84 between retakes within an 8- to 120-day period. Life impact ratings were correlated with frequency and severity of symptoms, with a clear linear relationship (R2>0.99). Furthermore, the aggregate MHQ scores were systematically related to both clinical burden and productivity. At one end of the scale, 89.08% (8986/10,087) of those in the Distressed category mapped to one or more disorders and had an average productivity loss of 15.2 (SD 11.2; SEM [standard error of measurement] 0.5) days per month. In contrast, at the other end of the scale, 0% (1/24,365) of those in the Thriving category mapped to any of the 10 disorders and had an average productivity loss of 1.3 (SD 3.6; SEM 0.1) days per month. Conclusions The MHQ is a valid and reliable assessment of mental health and well-being when delivered anonymously on the web.

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Geniesse, Caleb, Olaf Sporns, Giovanni Petri, and Manish Saggar. "Generating dynamical neuroimaging spatiotemporal representations (DyNeuSR) using topological data analysis." Network Neuroscience 3, no. 3 (January 2019): 763–78. http://dx.doi.org/10.1162/netn_a_00093.

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In this article, we present an open source neuroinformatics platform for exploring, analyzing, and validating distilled graphical representations of high-dimensional neuroimaging data extracted using topological data analysis (TDA). TDA techniques like Mapper have been recently applied to examine the brain’s dynamical organization during ongoing cognition without averaging data in space, in time, or across participants at the outset. Such TDA-based approaches mark an important deviation from standard neuroimaging analyses by distilling complex high-dimensional neuroimaging data into simple—yet neurophysiologically valid and behaviorally relevant—representations that can be interactively explored at the single-participant level. To facilitate wider use of such techniques within neuroimaging and general neuroscience communities, our work provides several tools for visualizing, interacting with, and grounding TDA-generated graphical representations in neurophysiology. Through Python-based Jupyter notebooks and open datasets, we provide a platform to assess and visualize different intermittent stages of Mapper and examine the influence of Mapper parameters on the generated representations. We hope this platform could enable researchers and clinicians alike to explore topological representations of neuroimaging data and generate biological insights underlying complex mental disorders.

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Martínez, Vania, Marcelo A. Crockett, Ajay Chandra, Sarah Shabbir Suwasrawala, Arkalgud Ramaprasad, Alicia Núñez, and Marcelo Gómez-Rojas. "State of Mental Health Research of Adolescents and Youth in Chile: An Ontological Analysis." International Journal of Environmental Research and Public Health 19, no. 16 (August 11, 2022): 9889. http://dx.doi.org/10.3390/ijerph19169889.

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Knowing the state of mental health research in adolescents and youth can be an important tool for decision-making, especially in contexts of limited resources. The aim of this study is to map the scientific research on adolescent and youth mental health in Chile using an ontological framework. We have mapped the population of research articles on mental health of adolescents and youth in Chile in Scopus, Web of Science, and SciELO databases onto the ontology. The PRISMA reporting guidelines were used to screen the 1688 items based on relevance, duplication, and version. The corpus of 346 articles was coded into the ontology through an iterative process among the seven authors. This ontological mapping shows isolated research efforts that have been carried out in Chile to explain the whole state of mental health in adolescents and youth. There is a lack of coordination between the priorities established by the decision-makers and the researchers. Our results coincide with the need to strengthen mental health research in the country, and to prioritizing those topics that contribute to decision-making based on the needs of the population.

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Zbukvic, Isabel, Demee Rheinberger, Hannah Rosebrock, Jaclyn Lim, Lauren McGillivray, Katherine Mok, Eve Stamate, Katie McGill, Fiona Shand, and Joanna C. Moullin. "Developing a tailored implementation action plan for a suicide prevention clinical intervention in an Australian mental health service: A qualitative study using the EPIS framework." Implementation Research and Practice 3 (January 2022): 263348952110657. http://dx.doi.org/10.1177/26334895211065786.

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Background: Tailoring implementation strategies to local contexts is a promising approach to supporting implementation and sustainment of evidence-based practices in health settings. While there is increasing research on tailored implementation of mental health interventions, implementation research on suicide prevention interventions is limited. This study aimed to evaluate implementation and subsequently develop a tailored action plan to support sustainment of an evidence-based suicide prevention intervention; Collaborative Assessment and Management of Suicidality (CAMS) in an Australian public mental health service. Methods: Approximately 150 mental health staff working within a regional and remote Local Health District in Australia were trained in CAMS. Semi-structured interviews and focus groups with frontline staff and clinical leaders were conducted to examine barriers and facilitators to using CAMS. Data were analysed using a reflexive thematic analysis approach and mapped to the Exploration, Preparation, Implementation and Sustainment (EPIS) framework and followed by stakeholder engagement to design a tailored implementation action plan based on a ‘tailored blueprint’ methodology. Results: A total of 22 barriers to implementing CAMS were identified. Based on the perceived impact on implementation fidelity and the feasibility of addressing identified barriers, six barriers were prioritised for addressing through an implementation action plan. These barriers were mapped to evidence-based implementation strategies and, in collaboration with local health district staff, goals and actionable steps for each strategy were generated. This information was combined into a tailored implementation plan to support the sustainable use of CAMS as part of routine care within this mental health service. Conclusions: This study provides an example of a collaborative approach to tailoring strategies for implementation on a large scale. Novel insights were obtained into the challenges of evaluating the implementation process and barriers to implementing an evidence-based suicide prevention treatment approach within a geographically large and varied mental health service in Australia. Plain language abstract: This study outlines the process of using a collaborative stakeholder engagement approach to develop tailored implementation plans. Using the Exploration Preparation Implementation Sustainment Framework, findings identify the barriers to and strategies for implementing a clinical suicide prevention intervention in an Australian community mental health setting. This is the first known study to use an implementation science framework to investigate the implementation of the clinical suicide prevention intervention (Collaborative Assessment and Management of Suicidality) within a community mental health setting. This work highlights the challenges of conducting implementation research in a dynamic public health service.

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Claudio, David, Sally Moyce, Tyler Albano, Ekeoma Ibe, Nick Miller, and Marshall O’Leary. "A Markov Chain Model for Mental Health Interventions." International Journal of Environmental Research and Public Health 20, no. 4 (February 16, 2023): 3525. http://dx.doi.org/10.3390/ijerph20043525.

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Poor mental health affects nearly one billion people worldwide and can end in suicide if not treated. Unfortunately, stigma and a lack of mental healthcare providers are barriers to receiving needed care. We developed a Markov chain model to determine whether decreasing stigma or increasing available resources improves mental health outcomes. We mapped potential steps in the mental health care continuum with two discrete outcomes: getting better or committing suicide. Using a Markov chain model, we calculated probabilities of each outcome based on projected increases in seeking help or availability of professional resources. Modeling for a 12% increase in awareness of mental health concerns yielded a 0.39% reduction in suicide. A 12% increase in access to professional help yielded a 0.47% reduction in suicide rate. Our results show that expanding access to professional services has a higher impact on reducing suicide rates than creating awareness. Any intervention towards awareness or access positively impacts reducing suicide rates. However, increased access results in a higher reduction in suicide rates. We have made progress in increasing awareness. Awareness campaigns help to increase recognition of mental health needs. However, focusing efforts on increasing access to care may have a higher impact on reducing suicide rates.

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Wood, Joanne. "Risk typologies of serious harm offenders managed under MAPPA: Mental health, personality disorders, and self-harm as distinguishing risk factors." Journal of Forensic Psychiatry & Psychology 18, no. 4 (December 2007): 470–81. http://dx.doi.org/10.1080/14789940701474889.

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Battaglia, A., R. Novellini, A. Maniero, A. Versari, and R. Zappoli. "Bit-mapped CNV complex, reaction time and clinical status in patients with primary presenile mental decline chronically treated with nicergoline." Electroencephalography and Clinical Neurophysiology 75 (January 1990): S9. http://dx.doi.org/10.1016/0013-4694(90)91749-f.

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Sayers, Janet. "Women and Mental Health: Challenging the Stereotypes. By Marian Barnes and Norma Maple. Birmingham: Venture Press. 1992. 196 pp. £9.95." British Journal of Psychiatry 163, no. 2 (August 1993): 271–72. http://dx.doi.org/10.1192/s0007125000181930.

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Chu, Yu-Xia, Wen-Qiang Cui, Fei Xu, Yuan-Yuan Pan, Yan-Hua Ma, Teng Chen, Si-Jing Wang, Hong-Bo Sun, Yan-Qing Wang, and Wen-Shan Sun. "Acupoint Embedding of Polyglactin 910 Sutures in Patients with Chronic Pain due to Cervical Spondylotic Radiculopathy: A Multicenter, Randomized, Controlled Clinical Trial." Evidence-Based Complementary and Alternative Medicine 2018 (September 26, 2018): 1–11. http://dx.doi.org/10.1155/2018/3465897.

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Objective. We aimed to investigate the effectiveness of acupoint polyglactin 910 (PGLA) embedding in patients with cervical spondylotic radiculopathy (CSR). Methods. A total of 102 CSR patients with neck and shoulder pain were recruited and assigned randomly into three groups: the sham acupoint embedding (SAE) group, the middle-layer acupoint PGLA embedding (MAPE) group, and the deep-layer acupoint PGLA embedding (DAPE) group. The primary outcomes were Visual Analog Scale (VAS) scores showing the analgesic effects of treatment. Secondary outcomes included clinical symptoms (evaluated by the Yasuhisa Tanaka 20 (YT-20) score and the neck disability index (NDI)) and patient health status (evaluated by the 36-item short-form survey (SF-36)) as reported in the trial. Results. Compared with the SAE group, VAS scores were significantly reduced at 1, 2, 3, 4, and 10 weeks after the first treatment in both the DAPE and MAPE groups (P < 0.001). Moreover, there were statistically significant increases in the weekly YT-20 scores and significant reductions of the weekly NDI scores compared with baseline values in both the DAPE and MAPE groups (P < 0.001). Compared with baseline values, both the physical component summary (PCS) and the mental component summary scores of the SF-36 at 2, 3, 4, and 10 weeks were significantly higher in the DAPE and MAPE groups (P < 0.001). There were significant lower VAS scores (P < 0.01), higher PCS scores (P < 0.05) at 3 weeks, and lower NDI scores (P < 0.05) at 4 weeks in the DAPE group compared with the MAPE group. Conclusions. Both DAPE and MAPE showed significant and long-lasting effects on alleviating pain and improving clinical symptoms as well as quality of life in CSR patients with neck and shoulder pain. A more intense effect was seen in the DAPE group compared with the MAPE group.

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Mears, Alex, Tim Kendall, Geraldine Strathdee, Robert Sinfield, and Ian Aldridge. "Progress on NICE guideline implementation in mental health trusts: meta-analyses." Psychiatric Bulletin 32, no. 10 (October 2008): 383–87. http://dx.doi.org/10.1192/pb.bp.108.019547.

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Aims and MethodTo investigate implementation of National Institute for Health and Clinical Excellence (NICE) guidelines in mental health, focusing on the schizophrenia guideline. Data analyses centred on implementation of the guideline, as well as looking at a set of markers mapped to the NICE principles of implementation and other identified clinical prerequisites. A self-report questionnaire tool was sent to senior executives at mental health trusts containing questions linked to the markers of implementation and clinical prerequisites; responses were analysed with data from the Healthcare Commission audit of implementation of the guideline to show key relationships.ResultsInformation from both data-sets (senior executive data collection and the audit) showed that implementation is patchy, with pockets of good implementation. Findings indicate that higher levels of implementation are linked to corporate commitment and leadership, as well as support from commissioners.Clinical ImplicationsImplementation might be improved by corporate commitment and leadership and better support from commissioners.

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Ghani, Lecturer Ali Abdul Ilah. "A Cognitive Stylistic study of poetic discourse." ALUSTATH JOURNAL FOR HUMAN AND SOCIAL SCIENCES 218, no. 1 (November 9, 2018): 17–34. http://dx.doi.org/10.36473/ujhss.v218i1.525.

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The study is concerned with the investigation of cognitive stylistic in the selected poem written by Emily Dickinson in order to show the effect of different cognitive stylistic devices especially the use of mental spaces on the interpretation of meaning. These mental spaces can help construct grammars that conceptualize the poet's world view. They are interacted and used not only in creation conceptual integration but also used to model dynamic mapping in the thought and language. The analysis has shown that cognitive stylistics is used as a device to provide a systematic and scientific approach to discourse authors and readers understanding of the world and explain how these interpretations are reflected in discourse organization. It tries to explain the way the cognitive processes are involved in meaning constructions. Furthermore, mental spaces can help construct grammars that conceptualize the poet's world view. Dickinson use of self-anaphor has created a world of possibilities, a world in which things can happen and be made to happen through the agencies of the self. Finally, metaphor is used as a scheme by which people conceptualize their experience to transfer, modify or blend mental constructs especially in the way by which one mental representation is mapped onto another when we read a text.

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Stephenson, Lucy A., Tania Gergel, Alex Ruck Keene, Larry Rifkin, and Gareth Owen. "Preparing for Mental Health Act reform: Pilot study of co-produced implementation strategies for Advance Choice Documents." Wellcome Open Research 7 (July 7, 2022): 182. http://dx.doi.org/10.12688/wellcomeopenres.17947.1.

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Background Advance Decision Making (ADM) is strongly supported by stakeholders but implementation remains challenging. In England and Wales, implementation strategies are urgently required to prepare for the introduction of mental health ‘Advance Choice Documents’ (ACDs) as part of Mental Health Act reforms. We report on a pilot project which aimed to co-produce and evaluate implementation strategies for ACDs with those who experience fluctuating mental capacity in the context of bipolar. Methods A co-produced prototype ACD template was piloted in ‘Plan, Do, Study Act’ (PDSA) cycles. Implementation strategies were co-produced with participants and mapped onto the Expert Recommendations for Implementing Change (ERIC) framework. Strategies were evaluated during thematically analysed qualitative interviews. Results We piloted the template with 17 service users during 5 successive PDSA cycles and conducted 75 in depth interviews with stakeholders. Key strategies identified as accessible, appropriate and feasible were: interactive assistance from an independent ‘supporter’, a structured template and active offers of involvement to service users and informal carers. Conclusions Mental health professionals and organisations must prepare for increased expectations around mental health ADM. We recommend further pilot projects and the establishment of ‘ACD workshops’. Resource is essential to fund independent ‘supporters’, training, network building and embedding ADM in clinical pathways.

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Parsekar, Shradha, Vijayashree Dhyani, Eti Rajwar, Jisha Krishna, Bhumika Tumkur Venkatesh, Kavitha Saravu, and Helmut Brand. "An overview of preventive and control strategies for common mental health disorders during infectious disease epidemics." F1000Research 11 (March 10, 2022): 297. http://dx.doi.org/10.12688/f1000research.74273.1.

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Background: The emergence of the COVID-19 pandemic has affected people’s mental health owing to different factors. The primary objective of this review was to systematically summarize available literature on the range of interventions for common mental health disorders during an infectious disease outbreak, specifically focusing on the COVID-19 pandemic. Methods: We searched PubMed, PsychInfo, Scopus, Web of Science, CINAHL, EPPI mapper and Google Scholar to identify English literature published since January 2010. We included scientific research studies and grey literature, extracted the information and summarized results thematically. Results: A range of common mental health disorders that affected populations from most parts of the world and associated factors were identified. We thematically classified intervention into the following: providing accurate and timely information and ensuring adequate supplies of daily need essentials; developing mindfulness and resilience that can revive self-sufficiency and self-awareness in stress management; early identification; providing necessary mental health care through professionals; and health system strengthening and capacity building interventions. Conclusion: There is an immediate need for a collective action through inter-sectoral coordination at community, national and international levels. Policymakers and program implementers should be prepared to tackle common mental health disorders amidst the ongoing COVID–19 pandemic and in future emerging and re-emerging infectious disease outbreaks.

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Panes, Iril. "Family Centeredness in Mental Health: A Concept Analysis." Journal of Health and Caring Sciences 2, no. 1 (June 26, 2020): 48–70. http://dx.doi.org/10.37719/jhcs.2020.v2i1.ra002.

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Background: Mental illness affects the entire family structure. The family members are the main provider of care that results in caregiving burden. Thus, the care given should encompass the entire family system, termed as family centeredness. Purpose: This study clarifies the concept of "family centeredness" in mental health to enhance individual and family cares living amid mental illness. Methods: This research employed Walker and Avant's method of Concept Analysis. Literature was reviewed, and the characteristics that appeared repeatedly were noted and categorized. Data were mapped according to its definition, antecedents, attributes, and consequences. Results: Three key defining attributes were identified: (a) A mutual, collaborative partnership between the patient, family and health care providers based on knowledge exchange, open communication and cooperation; (b) A supportive, professional relationship/bond/engagement among health care providers, patient and family characterized by empathy, understanding, respect and empowerment; and (c) Individualized care wherein the process is defined by the family is supported, enabling the opportunity to choose, control over decisions and empowerment. Conclusion: The result of the study clearly defines family centeredness as a health care approach in mental health that acknowledges the patient and family as the experts on themselves, involves families as collaborative partners in all aspects of services and decisions about care through mutually beneficial supportive partnerships with health care providers; to help patients make progress towards recovery.

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Hancock, P. A., M. H. Chignell, M. Vercruyssen, and M. Denhoff. "Experimental Evaluations of a Model of Mental Workload." Proceedings of the Human Factors Society Annual Meeting 33, no. 18 (October 1989): 1233–37. http://dx.doi.org/10.1177/154193128903301814.

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The present experiments were designed to test predictions from a model of mental workload. The model predicts non-linear increases in mental workload as perceived distance from a task goal grows and effective time for action is reduced. Diminution of mental workload is achieved by application of effort which brings the task goal into the region of acceptable time/distance constraints for successful resolution. Two experiments are reported which tested these assertions using the timepools performance task. Timepools is unique as a performance task in that it generates a spatial representation of a shrinking temporal target. The independent effects of path length, i.e., the number of sequential targets to be acquired, and shrink rate, i.e., the collapse time during which the circle is halved in area, may be assessed using performance variables such as reaction time (RT), movement time (MT), error rate (E), and the subjective perception of workload. Data from Experiment 1, indicate systematic effects for task related factors across performance and workload measures, although such a pattern was not isomorphically mapped to the a priori assumed difficulty of the task. In Experiment 2, shrink rate and path length had independent effect on RT and MT respectively, which were reflected in components of the individual workload scales. The ramifications with respect to the model are elaborated.

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Walsh, Karin S., and Megan N. Scott. "Neurocognitive Profile in a Case of Maple Syrup Urine Disease." Clinical Neuropsychologist 24, no. 4 (May 2010): 689–700. http://dx.doi.org/10.1080/13854040903527279.

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Spadaro, B., and N. Martin-Key. "A mixed methods evaluation of the current state of perinatal mental healthcare and users’ acceptability of a digital assessment for perinatal mental health." European Psychiatry 64, S1 (April 2021): S696—S697. http://dx.doi.org/10.1192/j.eurpsy.2021.1845.

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IntroductionPerinatal mental health symptoms commonly remain underdiagnosed in maternity care settings in the UK, with the COVID-19 pandemic having further disrupted access to adequate care provision. Digital technologies may offer innovative ways to support the mental health needs of women and partners and assist midwives in recognition of concerns.ObjectivesWe set to investigate the current state of perinatal mental healthcare provision in the UK and the acceptability of a digital mental health assessment.MethodsThe study entailed completing an online survey. 829 women, 103 partners, and 90 midwives participated in the study. Quantitative data were explored using descriptive statistics. Open-ended responses regarding the perceived benefits and barriers to using a digital mental health assessment were investigated using thematic analysis. Resultant themes were then mapped onto the Capability, Opportunity, and Motivation Model of Behaviour (COM-B model).ResultsThe provision of perinatal mental healthcare support was limited and varied across respondents, particularly throughout the COVID-19 pandemic. There was a strong interest in using a digital mental health assessment placed within maternity healthcare settings to screen, diagnose, and triage concerns (Figure 1). In-person and blended care approaches (i.e., in-person and remote support) were preferred by women and partners in the event of further care being advised (Figure 1). Identified barriers and benefits mainly related to physical opportunity (e.g., accessibility), psychological capability (e.g., cognitive skills) and automatic motivation (e.g., emotions).ConclusionsThis study provides proof-of-concept support for the development of a digital mental health assessment to inform clinical decision-making for perinatal mental health concerns.DisclosureNMK has financial interest in Psyomics Ltd., a company developing digital diagnostic devices for neuropsychiatric disorders.

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Field, Vida. "Women and Mental Health: Challenging the Stereotypes. Marian Barnes and Norma Maple. Venture Press 1992 No. of pages: 196. Price: $9.95." International Journal of Geriatric Psychiatry 8, no. 5 (May 1993): 446. http://dx.doi.org/10.1002/gps.930080516.

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Guerrini, Renzo, and William B. Dobyns. "Bilateral periventricular nodular heterotopia with mental retardation and frontonasal malformation." Neurology 51, no. 2 (August 1998): 499–503. http://dx.doi.org/10.1212/wnl.51.2.499.

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Background and Objective: Bilateral periventricular nodular heterotopia (BPNH) is a recently recognized malformation of neuronal migration in which nodular masses of gray matter line the walls of the lateral ventricles. Most affected individuals are females with epilepsy and normal intelligence, but no other congenital anomalies. Studies in families with multiple affected individuals, always all females, have mapped one BPNH gene to chromosome Xq28. Several other BPNH syndromes associated with mental retardation and epilepsy but without significant dysmorphic facial features have been observed in males only, which may also be X-linked. This report describes a new syndrome with BPNH.Methods: Clinical and MRI study and cognitive testing of two unrelated boys, aged 8 and 5.5 years, and review of the enlarging spectrum of syndromes associated with BPNH.Results: Similarities between the two boys are sufficient to delineate a new multiple congenital anomaly-mental retardation syndrome that consists of BPNH, regional cortical dysplasia, mild mental retardation, and frontonasal malformation.Conclusions: The cause of this unusual syndrome is unknown; based on linkage of other BPNH syndromes to chromosome Xq28 and the report of possible X-linked inheritance of frontonasal malformation, we suspect the cause is genetic, with possible X-linked inheritance.

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Journal articles on the topic 'Mappe mentali'

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