Journal articles: 'Malnutrition – Treatment'

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Schofield, W. N., Ann Ashworth, G. Tom Heikens, Mickey Chopra, and David Wilkinson. "Treatment of malnutrition." Lancet 345, no. 8952 (March 1995): 787–89. http://dx.doi.org/10.1016/s0140-6736(95)90665-7.

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Schofield, W. N. "Treatment of malnutrition." Lancet 345, no. 8960 (May 1995): 1303. http://dx.doi.org/10.1016/s0140-6736(95)90947-8.

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Nazarko, Linda. "Malnutrition: identification and treatment." British Journal of Healthcare Assistants 2, no. 6 (June 2008): 279–82. http://dx.doi.org/10.12968/bjha.2008.2.6.29544.

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Brewster, David, and Mark Manary. "Treatment of severe malnutrition." Lancet 345, no. 8947 (February 1995): 453. http://dx.doi.org/10.1016/s0140-6736(95)90435-2.

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Ashworth, Ann. "Treatment of Severe Malnutrition." Journal of Pediatric Gastroenterology and Nutrition 32, no. 5 (May 2001): 516–18. http://dx.doi.org/10.1097/00005176-200105000-00003.

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Harvey, Joanne. "Malnutrition: manifestations and treatment." Primary Health Care 3, no. 5 (May 1993): 20–21. http://dx.doi.org/10.7748/phc.3.5.20.s13.

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Ashworth, Ann. "Treatment of Severe Malnutrition." Journal of Pediatric Gastroenterology and Nutrition 32, no. 5 (May 2001): 516–18. http://dx.doi.org/10.1002/j.1536-4801.2001.tb07364.x.

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Goldstein, Mary Kane, and Jon D. Fuller. "INTENSITY OF TREATMENT IN MALNUTRITION." Primary Care: Clinics in Office Practice 21, no. 1 (March 1994): 191–206. http://dx.doi.org/10.1016/s0095-4543(21)00460-7.

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Xu, Z., Y. Chen, A. Huang, Z. Varghese, J. Moorhead, S. Powis, Q. Li, et al. "Treatment of malnutrition and anaemia." Clinical Kidney Journal 4, suppl 2 (June 1, 2011): 4.s2.9. http://dx.doi.org/10.1093/ndtplus/4.s2.9.

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Grajeta, Halina Grajeta. "Malnutrition- causes, consequences and treatment." Bromatologia i Chemia Toksykologiczna LIV, no. 2 (November 3, 2022): 133–47. http://dx.doi.org/10.32383/bct/152847.

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Niedożywienie jest poważnym problemem zdrowotnym i społecznym na świecie. Na ryzyko niedożywienia najbardziej narażone są dzieci, osoby starsze i przewlekle chore. Zaburzenia odżywiania, które prowadzą do niedoborów składników odżywczych pogarszają funkcjonowanie całego organizmu. Utrudniona regeneracja i większa liczba powikłań to zwiększona zachorowalność i śmiertelność osób niedożywionych. Niedożywienie najczęściej wynika z niewystarczającej podaży składników odżywczych i energii. Utrata masy ciała i sarkopenia towarzyszą upośledzeniu pracy układu krążenia, oddechowego, immunologicznego, pokarmowego oraz zaburzeniom gospodarki elektrolitowej. Ocena stanu odżywienia umożliwia rozpoznanie objawów nieodżywienia i dobranie odpowiedniego sposobu leczenia. Niedożywienie może być związane z sytuacją ekonomiczną i głodem, a także z chorobą nasilającą katabolizm lub pewnym stopniem niepełnosprawności, które powodują zmniejszenie podaży pokarmu, zaburzenia wchłaniania, zwiększoną utratę lub wzrost zapotrzebowania na składniki odżywcze. Istotne są także czynniki społeczne i psychologiczne, rodzaj stosowanej farmakoterapii, jak również fizjologiczne zmiany w organizmie towarzyszące starzeniu lub procesom zapalnym. Zaburzenie funkcji układu odpornościowego sprzyja nawracającym infekcjom. Stan niedożywienia wpływa na utrudnione gojenie się ran i zwiększa prawdopodobieństwo występowania odleżyn. Zaburza także funkcje przewodu pokarmowego i skóry, osłabia zdolności psychomotoryczne, prowadzi do zmian w obrębie tkanki mięśniowej i kości oraz wpływa na płodność i stan psychiczny. Negatywny wpływ niedożywienia na wyniki leczenia ma związek ze zwiększeniem toksyczności stosowanych leków, większą liczbą powikłań i zakażeń szpitalnych. Powoduje to wydłużenie hospitalizacji i znaczne zwiększenie kosztów opieki zdrowotnej. Leczenie żywieniowe obejmuje ocenę stanu odżywienia i zapotrzebowania organizmu na składniki odżywcze, konsultację dietetyczną oraz zastosowanie odpowiednio zbilansowanej diety, a następnie monitorowanie stanu odżywienia. Drogą z wyboru jest żywienie drogą przewodu pokarmowego (żywienie doustnie) za pomocą specjalnych diet przemysłowych (DSP), które są dostosowane składem do różnych sytuacji klinicznych. Celem pracy było przedstawienie, na podstawie przeglądu piśmiennictwa, przyczyn występowania niedożywienia, jego konsekwencji zdrowotnych oraz możliwości leczenia żywieniowego.

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Santosa, Agus, Sri Mulatsih, and Susetyowati Susetyowati. "Identifikasi risiko malnutrisi dan evaluasi status nutrisi pasien kanker anak dengan pengobatan kemoterapi." Jurnal Gizi Klinik Indonesia 15, no. 4 (April 30, 2019): 137. http://dx.doi.org/10.22146/ijcn.37015.

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Identification of malnutritional risk and nutrition status evaluation of pediatric cancer patients with chemotherapy treatmentBackground: Hospitalized childhood cancer patients had a high risk for malnutrition, either caused by the disease or effects of cancer treatment. Malnutrition in cancer patients gives negative impacts on treatment outcomes in the form of increasing morbidity and mortality rates. Nutrition screening for identifying malnutrition risks could prevent malnutrition in hospitals.Objectives: Investigating the influence of malnutrition risk during hospitalization on the changes in the nutritional status of childhood cancer patients with chemotherapy treatment. Methods: This research was observational research with the nested case-control design. The research subjects were childhood cancer patients aged 2-18 years old meeting the inclusion criteria. They were 64 in number consisting of the case group involving 32 patients and a control group involving the rest. During hospitalization, analyses of nutritional intake, change in body weight, nutritional status, and hospitalization period. Furthermore, the analyses of the influence of malnutrition risk on the outcome between those two groups were then compared. Results: There was a significant influence of malnutrition risk on less energy intake (p<0.001), less protein intake (p=0.002), weight loss >2% (p<0.001), poor nutritional status based on the BMI/U (p=0.011), and longer hospitalization (p=0.034). The group of patients with malnutrition risks had risks of 15.5 (CI 95%: 3.991-63.359) times higher for less energy intake, 6.12 (CI 95%: 1.675-24.906) times higher for less protein intake, and 45.3 (CI 95%: 5.666-1940.768) times higher for weight loss > 2% than the group of patients without malnutrition risks.Conclusions: Patients with a significant risk of malnutrition had less energy and protein intake, weight loss > 2%, poor nutritional status based on BMI/U, and longer hospitalization.

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Dipasquale, Valeria, Ugo Cucinotta, and Claudio Romano. "Acute Malnutrition in Children: Pathophysiology, Clinical Effects and Treatment." Nutrients 12, no. 8 (August 12, 2020): 2413. http://dx.doi.org/10.3390/nu12082413.

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Acute malnutrition is a nutritional deficiency resulting from either inadequate energy or protein intake. Children with primary acute malnutrition are common in developing countries as a result of inadequate food supply caused by social, economic, and environmental factors. Secondary acute malnutrition is usually due to an underlying disease causing abnormal nutrient loss, increased energy expenditure, or decreased food intake. Acute malnutrition leads to biochemical changes based on metabolic, hormonal, and glucoregulatory mechanisms. Most children with primary acute malnutrition can be managed at home with nutrition-specific interventions (i.e., counseling of parents, ensuring household food security, etc.). In case of severe acute malnutrition and complications, inpatient treatment is recommended. Secondary acute malnutrition should be managed by treating the underlying cause.

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Uzma, Saira, Raheela Mansoor, Bakht Jamal, and Luqman Khan. "Impact of Malnutrition on Survival and Treatment-Related Morbidity of Cancer in Children." Journal of Health and Rehabilitation Research 4, no. 2 (May 12, 2024): 696–701. http://dx.doi.org/10.61919/jhrr.v4i2.899.

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Background: Malnutrition is a prevalent and severe issue in pediatric oncology, affecting treatment outcomes and survival rates significantly. In developing countries, where access to comprehensive healthcare is limited, malnutrition's impact is even more profound, complicating treatment protocols and increasing morbidity and mortality rates among children with cancer. Objective: To evaluate the effects of malnutrition on survival rates and treatment-related morbidity in pediatric cancer patients, and to assess the efficacy of nutritional interventions in improving these outcomes. Methods: This retrospective study was conducted at SKMCH & RC, involving 160 newly diagnosed cancer patients aged between one and eighteen years. Patients were followed from January 2021 through March 2023. Malnutrition was assessed using WHO growth charts and defined using BMI and weight/height Z-scores. Data analysis was performed using SPSS software, version 25, focusing on survival rates, incidence of febrile neutropenia (FN), and nutritional status changes over time. Statistical significance was set at a p-value of 0.025. Results: At diagnosis, 42.5% (n=68) of the children were malnourished. After six months, 35% (n=56) remained malnourished, indicating some improvement. Malnourished children showed significantly lower survival rates, with those having a BMI Z-score ≤ -2 at six months post-diagnosis having a mortality rate HR of 4.05 (95% CI= 1.58-6.33, P = 0.009). Children experiencing a weight/height loss of >10% had an HR of 1.98 (95% CI= 1.23-6.91, P=0.04) for increased mortality. Increased episodes of FN were correlated with severe malnutrition (HR 7.32, 95% CI=1.98-10.14, P=0.0007). Conclusion: Malnutrition significantly impacts the survival rates and treatment-related morbidity in pediatric cancer patients. Early and aggressive nutritional interventions can improve survival outcomes and reduce the rate of hospitalizations due to complications like febrile neutropenia.

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M. MBUKEMBO, B. NIARE, O. DIALLO, Y.I. TRAORE, I. HALHOUSSEINI, S. DIARRA, C. KEITA, and I. BENGALY. "Evolution of the Treatment of Malaria in Acute Malnourished Patients at Ureni in Mali: From Systematic to Ethiological Treatment." International Journal of Medical Science and Health Research 07, no. 03 (2023): 18–25. http://dx.doi.org/10.51505/ijmshr.2023.7301.

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Both malaria and malnutrition have been implicated in impairing children's cognitive abilities, making it difficult for them to learn, and decreasing their school performance. Two previous versions of the national protocol for the management of acute malnutrition provide different guidelines. Our study aims to assess the extent of the association of malaria with acute malnutrition and the most appropriate version of the protocol. It is a retrospective study based on the records of children 6-59 months hospitalized at the URENI of the CSRéf of Kayes in 2019. The results show that on the basis of positive RDT, 0.9% of those admitted had malaria on acute malnutrition. The acute malnutrition patient is defined as a child from 24 to 59 months, referred to the URENI, treated with injectable Artesun, generally lasting 5 days in the program with a successful treatment rate of 75%. They have little diarrhea compared to other non-malarial patients. The 2017 version of the national protocol for the management of acute malnutrition is the most appropriate. Further studies are needed to support our findings.

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Hunter, Maddison, Jane Kellett, Kellie Toohey, Nathan M. D’Cunha, Stephen Isbel, and Nenad Naumovski. "Toxicities Caused by Head and Neck Cancer Treatments and Their Influence on the Development of Malnutrition: Review of the Literature." European Journal of Investigation in Health, Psychology and Education 10, no. 4 (October 2, 2020): 935–49. http://dx.doi.org/10.3390/ejihpe10040066.

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Malnutrition poses a significant problem for oncology patients, resulting in fatalities within this population. Patients with head and neck cancer (HNC) are at high risk, with up to 90% developing malnutrition. Common treatments used for HNC can often lead to adverse side effects, including oral health conditions, gastrointestinal upsets, and several metabolic changes. Consequently, treatments can cause inadequate nutritional intake, resulting in a reduction in energy consumption, and alterations in energy utilization, contributing to the development of malnutrition. Furthermore, the presence of these treatment toxicities, and the related malnutrition can lead to reduced quality of life, weight loss, and psychological distress. There are interventions available (nutritional, medicinal, and physical therapies) that have demonstrated potential effectiveness in reducing the severity of symptomatic toxicities, reducing the risk of malnutrition, and improving survival outcomes of patients with HNC. Based on the findings of this review, there is an urgent need for the implementation or continuation of multi-disciplinary strategies, as well as updated and improved guidelines to assist in the prevention and treatment of malnutrition caused by treatment-related toxicities in patients with HNC.

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Beirer, Angelika. "Malnutrition and cancer, diagnosis and treatment." memo - Magazine of European Medical Oncology 14, no. 2 (April 1, 2021): 168–73. http://dx.doi.org/10.1007/s12254-020-00672-3.

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Summary Background The prevalence of malnutrition in cancer patients ranges from about 20% to more than 70%. However, 10–20% of cancer patients’ deaths are related to malnutrition, not the malignancy itself. To reverse the pattern of weight loss, improve the patients’ quality of life, reduce the treatment toxicity, the psychological stress and the risk of mortality, the diagnosis of malnutrition should be made as early as possible to facilitate the best possible treatment. Methods A systematic literature search was conducted following guidelines of ESPEN (European Society for Clinical Nutrition), DGEM (German Society for Nutritional Medicine) and ASPEN (American Society for Parenteral and Enteral Nutrition). Results and conclusion To assess the risk of malnutrition, all cancer patients should be screened regularly with a valid screening tool (e.g., MUST [Malnutrition Universal Screening Tool], NRS [Nutritional Risk Screening] or PG-SGA [Scored Patient-Generated Subjective Global Assessment]). If risk of malnutrition is present, adequate nutritional therapy is recommended to stop involuntary weight loss. Patients should engage in exercise to maintain and improve muscle mass, strength and function. They should be offered regular dietetic counselling, and their muscle depletion should be monitored by determining fat-free mass. As cachectic patients in particular are at risk, the presence of cachexia should also be recognized at an early stage. Three consensus-based definitions are widely accepted: Fearon et al. and the EPCRC (European Palliative Care Research Collaborative) propose definitions specifically for cancer cachexia, while Evans et al. put forward a definition for cachexia associated with all types of underlying chronic diseases. However, if there is a cancer cachexia diagnosis, additional pharmacological and psychological treatment should be considered.

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R, Bhoye, Phadke M, Aguayo V, Irani S, Nair R, Pawar S, Patel T, Ganesh A, Khosla J, and Saunik S. "Domiciliary treatment of Severe Acute Malnutrition." International Journal of Nutrition 1, no. 4 (July 21, 2017): 1–6. http://dx.doi.org/10.14302/issn.2379-7835.ijn-17-1607.

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R, Bhoye, Phadke M, Aguayo V, Irani S, Nair R, Pawar S, Patel T, Ganesh A, Khosla J, and Saunik S. "Domiciliary treatment of Severe Acute Malnutrition." International Journal Of Nutrition 2, no. 4 (August 8, 2017): 1–5. http://dx.doi.org/10.14302/issn.2379-7835.ijn-17-607.

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Mahfuz, M. "Outpatient Treatment of Severe Acute Malnutrition." Science Translational Medicine 5, no. 191 (June 26, 2013): 191ec105. http://dx.doi.org/10.1126/scitranslmed.3006771.

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Ikizler, T. Alp, Rebecca L. Wingard, and Raymond M. Hakim. "Future Approaches to the Treatment of Malnutrition Malnutrition in Peritoneal Dialysis Patients: Etiologic Factors and Treatment Options." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 15, no. 5_suppl (April 1995): 63–66. http://dx.doi.org/10.1177/089686089501505s09.

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It is clear that malnutrition is common in chronic dialysis patients and is associated with increased morbidity and mortality. Evidence is accumulating that several measures can be taken to improve the nutritional status of these patients. An early start of dialysis, an increase in dialysis dose, the use of biocompatible membranes or dialysis solutions, and intensive nutritional counseling should be applied when necessary. If these measures fail, additional interventions, such as parenteral or enteral nutritional supplements, rhGH, and rhIGF -1, alone or in combination, should be tried.

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McCann, Linda M. "Malnutrition: Detection and Intervention." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 19, no. 2_suppl (February 1999): 527–32. http://dx.doi.org/10.1177/089686089901902s90.

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Malnutrition is common in patients with renal failure. Causes of malnutrition in this population are varied and sometimes specific to the method of renal replacement therapy. No single marker absolutely identifies malnutrition or tracks changes in status. Renal dietitians use a variety of parameters and techniques to identify malnutrition because many of the traditional markers can be skewed by renal disease and its comorbidities. Once malnutrition is identified, treatment is also complex and not well defined. Treatment is usually progressive in nature, ranging from intense nutritional counseling to total parenteral nutrition. Further research is needed to define optimal nutrition status, to refine techniques to maintain optimal nutrition status, to simplify the identification of malnutrition, and to improve the treatment for malnutrition.

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Stratton, Rebecca J. "Malnutrition: another health inequality?" Proceedings of the Nutrition Society 66, no. 4 (October 25, 2007): 522–29. http://dx.doi.org/10.1017/s0029665107005848.

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Malnutrition (undernutrition) is one of the many health inequalities facing governments in the 21st century. Malnutrition is a common condition affecting millions of individuals in the UK, particularly older adults, the sick and those cared for within the healthcare system. It costs the National Health Service >£7·3×109 annually. New data highlight marked geographical differences in the prevalence of malnutrition across England and an inter-relationship between deprivation, malnutrition and poor outcome. As malnutrition is a largely treatable condition, prompt identification and effective prevention and treatment of this costly condition is imperative. Routine screening for malnutrition in high-risk groups (e.g. the elderly and those in areas with high deprivation) and within the healthcare system should be a priority, with screening linked to appropriate plans for the management of malnutrition. Use should be made of specialised interventions, including oral nutritional supplements and artificial nutrition, to aid recovery and improve outcome, with skilled health professionals, including dietitians, involved where possible. Equity of access to nutritional services and treatments for malnutrition needs to occur across the UK and, although complex and multi-factorial, the effects of deprivation and other relevant socio-economic and geographical factors should be addressed. Ultimately, as malnutrition is a public health problem, its identification and treatment must become a priority for governments, healthcare planners and professionals.

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Collins, S., M. Myatt, and B. Golden. "Dietary treatment of severe malnutrition in adults." American Journal of Clinical Nutrition 68, no. 1 (July 1, 1998): 193–99. http://dx.doi.org/10.1093/ajcn/68.1.193.

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Kolaček, Sanja. "Treatment Methods and Goals in Pediatric Malnutrition." Annales Nestlé (English ed.) 67, no. 2 (2009): 85–93. http://dx.doi.org/10.1159/000226616.

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Waterlow, John. "Treatment of children with malnutrition and diarrhoea." Lancet 354, no. 9185 (October 1999): 1142. http://dx.doi.org/10.1016/s0140-6736(99)00329-3.

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Kostadinović, Jelena, Jelena Kotur-Stevuljević, Nevena Ivanović, and Zoran Andrić. "Malnutrition induced by cancer and oncology treatment." Hrana i ishrana 63, no. 1 (2022): 9–16. http://dx.doi.org/10.5937/hraish2201009k.

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Malnutrition as a consequence of the disease occurs most often in cancer patients, not only because of the cancer itself, but also because of the oncological treatment. The most important cause is chemotherapy, followed by radiotherapy and onco-surgery. Therefore, efforts are being made all over the world to find different ways to solve this difficult medical problem. Given that the mechanism of malnutrition caused by cancer is not sufficiently elucidated, the efforts made to design an adequate approach and treatment of this disorder are often unsuccessful. In order to improve the nutritional status of oncology patients, their nutritional disorder should be adequately diagnosed and then specific measurements should be performed (determination of body composition, the proportion of water, fat, muscle, as well as the determination of various biomarkers in the blood, for example markers inflammation). In this way, it is possible to formulate a multimodal approach to the treatment of malnutrition in oncology patients, which would include the intake of adequate foods, increased physical activity and personalized supplementation.

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Steer, Belinda, Jenelle Loeliger, Lara Edbrooke, Irene Deftereos, Erin Laing, and Nicole Kiss. "Malnutrition Prevalence according to the GLIM Criteria in Head and Neck Cancer Patients Undergoing Cancer Treatment." Nutrients 12, no. 11 (November 13, 2020): 3493. http://dx.doi.org/10.3390/nu12113493.

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Malnutrition is highly prevalent in people with head and neck cancer (HCN) and is associated with poorer outcomes. However, variation in malnutrition diagnostic criteria has made translation of the most effective interventions into practice challenging. This study aimed to determine the prevalence of malnutrition in a HNC population according to the Global Leadership Initiative on Malnutrition (GLIM) criteria and assess inter-rater reliability and predictive validity. A secondary analysis of data available for 188 patients with HNC extracted from two cancer malnutrition point prevalence studies was conducted. A GLIM diagnosis of malnutrition was assigned when one phenotypic and one etiologic criterion were present. Phenotypic criteria were ≥5% unintentional loss of body weight, body mass index (BMI), and subjective evidence of muscle loss. Etiologic criteria were reduced food intake, and presence of metastatic disease as a proxy for inflammation. The prevalence of malnutrition was 22.6% (8.0% moderately malnourished; 13.3% severely malnourished). Inter-rater reliability was classified as excellent for the GLIM criteria overall, as well as for each individual criterion. A GLIM diagnosis of malnutrition was found to be significantly associated with BMI but was not predictive of 30 day hospital readmission. Further large, prospective cohort studies are required in this patient population to further validate the GLIM criteria.

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Nguyen, Van Trinh, Bich Cham Nguyen, Nhat Duy Nguyen, Van Thi Vo, Minh Thu Nguyen, Duc Tri Nguyen, Tri Dien Lu, and Thach Ky Dieu. "EFFECTS OF ACUTE MALNUTRITION ON THE RESULTS OF PNEUMONIA TREATMENT IN CHILDREN FROM 2 MONTHS TO 5 YEARS OLD." Tạp chí Y Dược học Cần Thơ, no. 7 (May 16, 2024): 163–70. http://dx.doi.org/10.58490/ctump.2024i7.2975.

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Background: Pneumonia is a very common disease in children, especially children under 5 years old, due to their immature immune system not being able to fight against environmental pathogens. Malnutrition affects the severity and outcome of pneumonia treatment. Objectives: 1) To describe the results of pneumonia treatment in acute malnutrition children from 2 months to 5 years old. 2) To determine the relationship between acute malnutrition and the results of pneumonia treatment in children from 2 months to 5 years old. Materials and method: 174 children with pneumonia with acute malnutrition from 2 months to 5 years old are receiving inpatient treatment at Can Tho Children's Hospital, Disease group: Children diagnosed with pneumonia according to the Ministry of Health 2014: Children with cough, fever accompanied by at least one of the signs of rapid breathing according to age, chest indrawing (the lower part of the chest indents during inhalation), or rales lung abnormalities (moisture rales, bronchial rales, crackles, etc.) [6]. AND children diagnosed with acute malnutrition according to the Ministry of Health 2016: Children have 1 of 2 anthropometric conditions: arm circumference (MUAC) or weight for height (CN/CC) lower than the normal threshold for age and gender (in which, severe malnutrition with MUAC<115 mm or CN/CC<-3SD, moderate malnutrition with 115mm≤MUAC<125mm or -3SD≤CN/CC<-2SD) [7]. Control group: children diagnosed with pneumonia without acute malnutrition. Disease control research. Results: Some characteristics after treatment: antibiotic combination was 28.2%, antibiotic change counted for 31.6%, respiratory support was 19.0%, intensive care unit transfer was 6.9%, curative treatment results was 98.7%. There is a significant correlation between acute malnutrition with pneumonia and the characteristics of treatment outcomes: severe pneumonia (p<0.001), combined with antibiotics (p<0.001), respiratory support (p=0.012) and transfer to Intensive Care Unit (p=0.017). Acute malnutrition with pneumonia was not significantly different from changing antibiotics (p<0.625) and death after treatment (p=0.560). Conclusion: Acute malnutrition is statistically significantly different from the severity of pneumonia, antibiotic combination, respiratory support, and transfer to the Intensive Care Unit.

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Kerr, Kirk, Cory Brunton, and Mary Beth Arensberg. "Outcomes and Treatment Costs of Skilled Nursing Facility Patients with Pressure Injuries and Malnutrition." Innovation in Aging 5, Supplement_1 (December 1, 2021): 1012–13. http://dx.doi.org/10.1093/geroni/igab046.3629.

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Abstract Skilled nursing facilities (SNF) provide care for individuals requiring skilled care while transitioning to a more permanent residence post hospitalization. This analysis shows that diagnosed malnutrition and pressure injuries (PI) adversely impact SNF patients’ health and recovery. Length of SNF stay, total charges, and discharge disposition were analyzed using SNF claims from 2016-2020 Centers for Medicare & Medicaid Services (CMS) Standard Analytical File databases. An average of 4.5% SNF patients had diagnosed PIs, and 4.9% had diagnosed malnutrition. Patients with diagnosed malnutrition were more likely to have PIs than patients without diagnosed malnutrition (11.9% vs 4.1%). Patients with PIs had higher charges ($12,304 vs. $10,937), were less likely to be discharged home (11.1% vs 18.9%), and more likely to be discharged to a hospital (15.8% vs 11.0%) or deceased (2.8% vs 1.6%). Patients with diagnosed malnutrition displayed a similar pattern for charges ($11,587 vs $10,969), and discharge to home (14.5% vs 18.8%), hospital (13.5 vs 11.1%) or deceased (2.8% vs 1.6%). Length of SNF stay did not differ between patients with and without PIs (18.5 vs 18.6) and was slightly shorter for patients with diagnosed malnutrition (17.3 vs 18.9). While higher probability of rehospitalization or death could impact these results, drivers behind these differences need further investigation. Because malnourished patients were more likely to have PIs and both PI and malnutrition are associated with poorer patient discharge outcomes and higher costs, efforts to identify malnutrition and implement proper nutrition interventions should be prioritized as part of SNF quality improvement initiatives.

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Jahangirporia, Dhara N., Chikitsa D. Amin, and Amiruddin M. Kadri. "Epidemiological Proileof Children with Malnutrition at Child Malnutrition Treatment Center (CMTC)in Saurashtra Region." Healthline 14, no. 4 (December 31, 2023): 325–31. http://dx.doi.org/10.51957/healthline5642023.

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Introduction: Adequate Nutrition is important for optimum growth, immunity, neurological and cognitive development of the child. Malnutrition leads to illness and mortality among under 5 children. Nearly 40% under 5 children are malnourished in Gujarat despite many nutritional programmes. Objectives: To assess the epidemiological factors of malnourished children at Child Malnutrition Treatment Centre (CMTC) and to ind outthe association between epidemiological factors and nutritional status of study participants. Method: A cross-sectional study was conducted on Children admitted at CMTC at Narayan Nagar Urban Health Center, the only one and newly established CMTC in Rajkot city in year 2015. Study duration was 14 months. Interview of mothers of 120 children was conducted to know epidemiological factors of malnourished children. Weight on admission was noted from register. Pre-formed, semi-structured proforma used. Results: Out of 120 children, 5.8%, 55.8%, 34.2% and 4.2% were from <1, 1-3, 3-5 and >5 year age groups respectively. Nearly 40% children belonged to Socioeconomic Class IV. The proportion of Low Birth Weight children was 40%. Current feeding practice was appropriate in 10.8% children according to IMNCI guideline. Upper Respiratory Tract Infection occurred in 76.7% children with average 4.5 episodes. High birth order of children is statistically signi icant with severity of malnutrition. Birth weight and feeding practices of children were not associated with grade of malnutrition. Conclusion: Need based education of mothers for preventing low birth weight, exclusive breastfeeding, complementary feeding, quantity and type of routine diet etc. should be given.

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Gandullia, Ludovica, Irina Mihaela Cazacu, Vlad Mihai Croitoru, and Paolo Gandullia. "Nutritional Support Indications in Patients with Gastroesophageal Cancer – A Review." Journal of Medical and Radiation Oncology 2, no. 2 (December 1, 2022): 11–20. http://dx.doi.org/10.53011/jmro.2022.02.03.

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"Nutritional support is an essential part of cancer care. Malnutrition is a common feature in cancer patients and has a negative impact on the quality of life and treatment tolerance. Patients with digestive cancers are at higher risk of malnutrition due to the gastrointestinal impairment caused by their disease. However, most of them have insufficient access to nutritional support. Early identification of patients at risk of malnutrition is crucial in order to start an adequate nutritional support. Robust evidence showed that nutritional support can reduce length of hospitalisation, decrease treatment-related toxicity, and improve quality of life and physical function. Nutritional intervention can improve outcomes and help patients in the successful completion of oncological treatments by preventing malnutrition. The aim of this review is to provide a comprehensive overview of nutritional interventions for patients with gastroesophageal cancers. "

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Li, Zhuo, Zulipikaer Maimaiti, Zhi-Yuan Li, Jun Fu, Li-Bo Hao, Chi Xu, and Ji-Ying Chen. "Moderate-to-Severe Malnutrition Identified by the Controlling Nutritional Status (CONUT) Score Is Significantly Associated with Treatment Failure of Periprosthetic Joint Infection." Nutrients 14, no. 20 (October 21, 2022): 4433. http://dx.doi.org/10.3390/nu14204433.

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The prevalence and role of malnutrition in periprosthetic joint infection (PJI) remain unclear. This study aimed to use measurable nutritional screening tools to assess the prevalence of malnutrition in PJI patients during two-stage exchange arthroplasty and to explore the association between malnutrition and treatment failure. Our study retrospectively included 183 PJI cases who underwent 1st stage exchange arthroplasty and had available nutritional parameters, of which 167 proceeded with 2nd stage reimplantation. The recently proposed Musculoskeletal Infection Society (MSIS) Outcome Reporting Tool was used to determine clinical outcomes. The Controlling Nutritional Status (CONUT), Nutritional Risk Index (NRI), and Naples Prognostic Score (NPS) were used to identify malnutrition at 1st and 2nd stage exchange, respectively. Multivariate logistic regression analyses were performed to determine the association between malnutrition and treatment failure. Restricted cubic spline models were further used to explore the dose–response association. Additionally, risk factors for moderate-to-severe malnutrition were evaluated. Malnourished patients identified by CONUT, NPS, and NRI accounted for 48.1% (88/183), 98.9% (181/183), and 55.7% (102/183) of patients at 1st stage, and 9.0% (15/167), 41.9% (70/167), and 43.1% (72/167) at 2nd stage, indicating a significant improvement in nutritional status. We found that poorer nutritional status was a predictor of treatment failure, with CONUT performing best as a predictive tool. Moderate-to-severe malnutrition at 1st stage identified by CONUT was significantly related to treatment failure directly caused by PJI (odds ratio [OR] = 5.86), while the OR was raised to 12.15 at 2nd stage (OR = 12.15). The linear dose–response associations between them were also confirmed (P for nonlinearity at both 1st and 2nd stage > 0.05). As for total treatment failure, moderate-to-severe malnutrition as determined by CONUT was associated with a 1.96-fold and 8.99-fold elevated risk at the 1st and 2nd stages, respectively. Age ≥ 68 years (OR = 5.35) and an increased number of previous surgeries (OR = 2.04) may be risk factors for moderate-to-severe malnutrition. Overall, the prevalence of malnutrition in PJI patients is very high. Given the strong association between moderate-to-severe malnutrition identified by CONUT and PJI treatment failure, COUNT could be a promising tool to evaluate the nutritional status of PJI patients to optimize treatment outcomes.

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Chiou Yi, Ho, and Ban Zhen Hong. "Prevalence of Malnutrition and Associated Factors in Newly Diagnosed Upper Gastrointestinal Cancer Patients Before Treatment." Asian Pacific Journal of Cancer Care 9, no. 2 (June 24, 2024): 267–75. http://dx.doi.org/10.31557/apjcc.2024.9.2.267-275.

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Introduction: Upper gastrointestinal cancers (UGIC) related malnutrition has been found to harm cancer prognosis and treatment outcomes. The study purposed to investigate the prevalence of malnutrition and associated factors in newly diagnosed upper gastrointestinal cancer patients before treatment. Material and Methods: A cross-sectional study included newly diagnosed UGIC patients from October 2020 to March 2022. Sociodemographic, clinical (type, stage, and comorbidities), functional [Eastern Cooperative Oncology Group (ECOG) Performance Status Scale], anthropometric measures [weight, height, the percentage of weight loss past 1-month], biochemical profiles [full blood count and albumin], total daily energy protein intake, and malnutrition level [Subjective Global Assessment (SGA)] were assessed. Results: The study recruited 409 participants, and 92.1% were malnourished. The mean for age, weight, percentage of weight loss past 1-month, total daily energy and protein intake, SGA score, and serum albumin of participants were 60.3±12.5years, 57.8±15.1kg, -8.2±6.0%, 17±5kcal/ kg/day, 0.7±0.1g/kg/day, 12.2±4.5 and 35.6±6.1g/L respectively. About 88% and 96% experienced vomiting and dysphasia, respectively; 51.3% was ECOG scale 2. According to a multiple linear regression test, the percentage of weight loss past 1 month, serum albumin, dyspepsia, dysphagia, lymphocytes, and gender (male) were the significant factors associated with malnutrition. Conclusion: UGIC patients are especially susceptible to malnutrition which might cause a decrease in therapy sensitivity, quality of life, and survival rate. Currently, proposed factors associated with malnutrition can assist in identifying UGIC-related malnutrition. Early nutrition screening and assessment followed with timely nutrition intervention is important to identify malnutrition and optimize nutrition status before treatment.

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Karabulut, Senem, İzzet Dogan, Çiğdem Usul Afşar, Mehmet Karabulut, Sule Karaman, Ferhat Ferhatoglu, and Didem Tastekin. "Does nutritional status affect treatment tolarability, response, and survival in metastatic colorectal cancer patients? Results of prospective multicenter study." Journal of Clinical Oncology 38, no. 4_suppl (February 1, 2020): 70. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.70.

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70 Background: The efficacy and tolerability of modern cytotoxic chemotherapy regimens used in malnourished metastatic colorectal cancer patients is uncertain. The aim of this study was to investigate the effect of malnutrition on efficacy and tolerability of cytotoxic chemotherapy and overall survival in mCRC patients. Methods: In this multicenter study, demographic, oncologic and nutritional data were collected prospectively from mCRC patients. Nutritional status were evaluated on the basis of NRI, BMI and WL before the first chemotherapy, after the first and second chemotherapy. To determine the inter-treatment weight loss toxicity assessment was included to theese parameters after each chemotherapy. NRIs were examined in 3 categories as ‘no malnutrition’ (NRI >97.5), ‘moderate malnutrition’ (97.5 ≥ NRI ≥83.5) or ‘severe malnutrition’ (NRI <83.5). Response to treatment and drug-induced toxicities were assessed based on RECIST 1.1 and CTCAE version 4.0 respectively. Results: 137 mCRC patients were prospectively included. Median age was 48 (range 18-83). Primary location was colon in 66% of patients, 84% of them source was left colon. Malnutrition was detected in 39% of the cases. Response rate to treatment was 24 %. Moderate / severe malnutrition was associated with multipl site of metastases, WHO PS of 1, over the median value of CEA/CA 19-9 levels (p=0.003, p=0.03, p<0.001, and p=0.02; respectively). Hypoalbuminemia and moderate/severe malnutrition were associated with all types of toxicity (p<0.001 and p<0.001). Moderate/severe malnutrition was associated with thrombocytopenia, and diarrhea following chemotherapy predominately, (p=0.02 and p=0.04; respectively). In moderate/severe malnutrition group median overall survival was prominently shorter than those with no malnutrition [6.6 moths (95 %CI, 5.6-7.6) vs 11.9 moths (95 % CI, 11.1-12.7) respectively, p<0.001]. Conclusions: Our study showed that moderate/severe malnutrition in mCRC patients was associated with decreased overall survival and increased chemotherapy toxicity.

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Singh, Shri Kant, Alka Chauhan, Santosh Kumar Sharma, Parul Puri, Sarang Pedgaonkar, Laxmi Kant Dwivedi, and Lindsey Smith Taillie. "Cultural and Contextual Drivers of Triple Burden of Malnutrition among Children in India." Nutrients 15, no. 15 (August 6, 2023): 3478. http://dx.doi.org/10.3390/nu15153478.

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This study examines malnutrition’s triple burden, including anaemia, overweight, and stunting, among children aged 6–59 months. Using data from the National Family Health Survey-5 (2019–2021), the study identifies risk factors and assesses their contribution at different levels to existing malnutrition burden. A random intercept multilevel logistic regression model and spatial analysis are employed to identify child, maternal, and household level risk factors for stunting, overweight, and anaemia. The study finds that 34% of children were stunted, 4% were overweight, and 66% were anaemic. Stunting and anaemia prevalence were higher in central and eastern regions, while overweight was more prevalent in the north-eastern and northern regions. At the macro-level, the coexistence of stunting, overweight, and anaemia circumstantiates the triple burden of childhood malnutrition with substantial spatial variation (Moran’s I: stunting-0.53, overweight-0.41, and anaemia-0.53). Multilevel analysis reveals that child, maternal, and household variables play a substantial role in determining malnutrition burden in India. The nutritional health is significantly influenced by a wide range of determinants, necessitating multilevel treatments targeting households to address this diverse group of coexisting factors. Given the intra-country spatial heterogeneity, the treatment also needs to be tailor-made for various disaggregated levels.

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Sahathevan, Sharmela, Ban-Hock Khor, Hi-Ming Ng, Abdul Halim Abdul Gafor, Zulfitri Azuan Mat Daud, Denise Mafra, and Tilakavati Karupaiah. "Understanding Development of Malnutrition in Hemodialysis Patients: A Narrative Review." Nutrients 12, no. 10 (October 15, 2020): 3147. http://dx.doi.org/10.3390/nu12103147.

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Hemodialysis (HD) majorly represents the global treatment option for patients with chronic kidney disease stage 5, and, despite advances in dialysis technology, these patients face a high risk of morbidity and mortality from malnutrition. We aimed to provide a novel view that malnutrition susceptibility in the global HD community is either or both of iatrogenic and of non-iatrogenic origins. This categorization of malnutrition origin clearly describes the role of each factor in contributing to malnutrition. Low dialysis adequacy resulting in uremia and metabolic acidosis and dialysis membranes and techniques, which incur greater amino-acid losses, are identified modifiable iatrogenic factors of malnutrition. Dietary inadequacy as per suboptimal energy and protein intakes due to poor appetite status, low diet quality, high diet monotony index, and/or psychosocial and financial barriers are modifiable non-iatrogenic factors implicated in malnutrition in these patients. These factors should be included in a comprehensive nutritional assessment for malnutrition risk. Leveraging the point of origin of malnutrition in dialysis patients is crucial for healthcare practitioners to enable personalized patient care, as well as determine country-specific malnutrition treatment strategies.

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Hlaing, Thein. "Ascariasis and childhood malnutrition." Parasitology 107, S1 (January 1993): S125—S136. http://dx.doi.org/10.1017/s0031182000075557.

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SUMMARYThe present review will examine epidemiological perspectives and be confined mainly to the results of those field studies published since 1975 in order to provide concrete scientific evidence of the effect of ascariasis on childhood malnutrition, particularly on growth. The field studies were done in many developing countries from Africa, Asia and Latin America, using cross-sectional and intervention studies in which anthelmintics were employed, with different dosing frequency and follow-up periods ranging from 33 days to 2 years. In general, a better nutritional status in terms of growth, lactose tolerance, vitamins A and C, and albumin levels were observed amongAscaris–free or treated than amongAscaris–infected or untreated children even in cross-sectional or non-randomized studies. More importantly, the improvement in weight or height after chemotherapeutic treatment was found to be significant particularly in those randomized controlled studies with an initially high prevalence of ascariasis and malnutrition, a low prevalence of other intestinal parasites, repetitive and regular treatments of children with tetramisole, levamisole or pyrantel, within a period of 12 or 24 months. Reasons for failures to detect improved growth in some studies are provided. This review strongly indicates thatA. lumbricoidesinfection definitely retards childhood growth.

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Hassan, Syed Hafeez ul. "Malnutrition Challenge Therapeutic Strategy." Journal of Aziz Fatimah Medical & Dental College 1, no. 2 (November 19, 2019): 77–78. http://dx.doi.org/10.55279/jafmdc.v1i2.58.

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SUMMARYMalnutrition is a broad term which describes nutritional related diseases caused by over and under nutrition, found in the hospitals or in famines. Therefore malnutrition can be categorized as over nutrition and obesity resulting into metabolic syndrome characterized by hyperglycemia, hypertension, dyslipidemia, hyperuricemia and decreased vitamin D in some cases. Whereas under nutrition with inflammation can be as a result of chronic illness, acute illness/injury or simply decreased dietary intake when there is no inflammation. The initial assessment can be done by simple clinical measures such as recording weight and BMI and serum albumin estimation. The adjusted nutrition plan during sickness involves assessment of calories requirement under the circumstances and then to use appropriate nutrition or premade nutrition formulas to meet the new requirements during disease or after surgery. The therapeutic strategy which also includes nutrition assessment and treatment may result in decrease in complications hence decreased hospital stay and cost of treatment having better hospital outcomes.

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Cristina, Neri Maria, and d’Alba Lucia. "Nutrition and Healthy Aging: Prevention and Treatment of Gastrointestinal Diseases." Nutrients 13, no. 12 (November 30, 2021): 4337. http://dx.doi.org/10.3390/nu13124337.

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Nutritional well-being is a fundamental aspect for the health, autonomy and, therefore, the quality of life of all people, but especially of the elderly. It is estimated that at least half of non-institutionalized elderly people need nutritional intervention to improve their health and that 85% have one or more chronic diseases that could improve with correct nutrition. Although prevalence estimates are highly variable, depending on the population considered and the tool used for its assessment, malnutrition in the elderly has been reported up to 50%. Older patients are particularly at risk of malnutrition, due to multiple etiopathogenetic factors which can lead to a reduction or utilization in the intake of nutrients, a progressive loss of functional autonomy with dependence on food, and psychological problems related to economic or social isolation, e.g., linked to poverty or loneliness. Changes in the aging gut involve the mechanical disintegration of food, gastrointestinal motor function, food transit, intestinal wall function, and chemical digestion of food. These alterations progressively lead to the reduced ability to supply the body with adequate levels of nutrients, with the consequent development of malnutrition. Furthermore, studies have shown that the quality of life is impaired both in gastrointestinal diseases, but especially in malnutrition. A better understanding of the pathophysiology of malnutrition in elderly people is necessary to promote the knowledge of age-related changes in appetite, food intake, homeostasis, and body composition in order to better develop effective prevention and intervention strategies to achieve healthy aging.

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Kushwaha, Sandeep, Shivam Dubey, S. Sambath, and Shally Khurana. "Malnutrition among masses." IP Journal of Nutrition, Metabolism and Health Science 4, no. 4 (February 15, 2022): 137–42. http://dx.doi.org/10.18231/j.ijnmhs.2021.024.

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Malnutrition keeps on being significant wellbeing trouble in emerging nations. It is universally the main danger factor for ailment and passing, with a huge number of pregnant ladies and small kids especially impacted. Lack of healthy sustenance in created nations is tragically even more normal in circumstances of neediness, social separation, and substance abuse. Lack of healthy sustenance, which is regularly neglected by clinicians, is normal and has wide-running impacts on physiological capacity. It is related to expanded paces of dreariness and mortality in clinic patients and essentially builds medical care costs. Execution of a basic screening device distinguishes patients in danger and permits proper treatment to be founded; this can altogether work on clinical results and decrease medical services consumption.

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Laur, Celia V., Tara McNicholl, Renata Valaitis, and Heather H. Keller. "Malnutrition or frailty? Overlap and evidence gaps in the diagnosis and treatment of frailty and malnutrition." Applied Physiology, Nutrition, and Metabolism 42, no. 5 (May 2017): 449–58. http://dx.doi.org/10.1139/apnm-2016-0652.

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There is increasing awareness of the detrimental health impact of frailty on older adults and of the high prevalence of malnutrition in this segment of the population. Experts in these 2 arenas need to be cognizant of the overlap in constructs, diagnosis, and treatment of frailty and malnutrition. There is a lack of consensus regarding the definition of malnutrition and how it should be assessed. While there is consensus on the definition of frailty, there is no agreement on how it should be measured. Separate assessment tools exist for both malnutrition and frailty; however, there is intersection between concepts and measures. This narrative review highlights some of the intersections within these screening/assessment tools, including weight loss/decreased body mass, functional capacity, and weakness (handgrip strength). The potential for identification of a minimal set of objective measures to identify, or at least consider risk for both conditions, is proposed. Frailty and malnutrition have also been shown to result in similar negative health outcomes and consequently common treatment strategies have been studied, including oral nutritional supplements. While many of the outcomes of treatment relate to both concepts of frailty and malnutrition, research questions are typically focused on the frailty concept, leading to possible gaps or missed opportunities in understanding the effect of complementary interventions on malnutrition. A better understanding of how these conditions overlap may improve treatment strategies for frail, malnourished, older adults.

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Gökçe, Şule, Aslı Aslan, and Feyza Koç. "Malnutrition: Already exist and is being overlooked?" Journal of Clinical and Laboratory Research 2, no. 5 (June 3, 2021): 01–08. http://dx.doi.org/10.31579/2768-0487/024.

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Background: Malnutrition is defined as deficiency and or imbalance of nutrients and energy and may produce a negative effect on the growth, maintenance, and specific functions of the body. This study purposed to determine the nutritional situation, to define the presence of malnutrition, to detect the deficiencies of micronutrients of the children admitted to a pediatric tertiary hospital. Methods: A retrospective, cross‑sectional, single unit-based study in pediatric patients admitted to the pediatric wards for differential diagnosis or treatment was conducted between November 2017 and December 2019. The anthropometric measurements were figured out on hospital admission of all pediatric patients. The pediatric patients diagnosed with malnutrition were assessed to detect their nutritional status/feeding habits and to identify any associated factors. Results: A total of 1206 children were hospitalized with an acute illness diagnosis and/or treatment during the study period. One hundred fifteen patients were noted to have malnutrition; acute malnutrition (wasting) (weight for height z-score < - 2 SDS) (n=51/115, 44.3%) and chronic malnutrition (stunted) (height-for-age < −2 SDS) was detected in 64/115 (55.7%) patients; the prevalence of wasting, and stunting was 4.2% and 5.3%, respectively. Conclusions: Our study suggests that it should be performed an assessment of nutritional status/ history and anthropometric measurements every admission to the hospital in order to provide healthy growth development in childhood, particularly under 2 of age and interventions should be strengthened for general child health.

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Djoko, S. W., E. Kembauw, and I. B. D. Kapelle. "Moringa oleifera milk powder as a supplementary food for malnutrition children (SUSUKE)." IOP Conference Series: Earth and Environmental Science 883, no. 1 (October 1, 2021): 012090. http://dx.doi.org/10.1088/1755-1315/883/1/012090.

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Abstract Moringa oleifera are known throughout the world as a nutrition plants, WHO has introduced moringa as an alternative food to overcome malnutrition. In Africa and Asia Moringa leaves are recommended as a nutrient-rich supplements for nursing mothers and children during infancy phase. Moluccas is one of the top 5 regions with quite high rates of malnutrition, while rich in natural products, the lack of knowledge and poor processing method results in nutrients unable to be properly absorbed. Moringa milk-powder can be the answers to malnutrition problems. Methods: This Study used a Nested case-control design, subject were all children aged 1 month-12 years who were diagnosed with malnutrition using WHO and CDC chart during reseach. Result: Sample size was 60 children’s 30 subjects are using malnutrition treatment and moringa milk powder and 30 subjects are using only malnutrition treatment. Conclusion: Moringa milk powder have a benefit for malnutrition children.

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Jackson, Helena. "Nutrition screening in hospitalised patients—a renal perspective." Journal of Kidney Care 4, no. 3 (May 2, 2019): 126–30. http://dx.doi.org/10.12968/jokc.2019.4.3.126.

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Malnutrition is common in hospitalised patients, and studies indicate that 50% patients who are admitted to specialist renal wards may be malnourished. The detection of malnutrition is challenging, particularly in patients with renal disease. Nutrition screening is a brief malnutrition risk assessment and provides the opportunity for early detection and prompt treatment of malnutrition

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Pinar, Eymen, Bilal Berke Ayvaz, Erkan Akkus, Ipek Ulkersoy, Tugce Damla Dilek, Yilmaz Zindar, Fitnat Ulug, et al. "Exploring the Influence of Concurrent Nutritional Therapy on Children with Spinal Muscular Atrophy Receiving Nusinersen Treatment." Children 11, no. 8 (July 23, 2024): 886. http://dx.doi.org/10.3390/children11080886.

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Background This study examines spinal muscular atrophy (SMA), a neuromuscular disease associated with malnutrition. Our goals are to assess how effectively screening tools can detect malnutrition and evaluate the impact of nutritional interventions on neurological outcomes, particularly motor functions. Methods Thirty-seven genetically diagnosed SMA patients (types 1, 2, and 3) under nusinersen therapy were included in the study. The nutritional status of these patients was assessed by using anthropometric measurements, including height for age (HFA), weight for height (WFH), and body mass index (BMI) before and after the study. Additionally, the risk of malnutrition was determined using screening tools, namely the Pediatric Yorkhill Malnutrition Score (PYMS) and the Screening Tool for the Assessment of Malnutrition in Pediatrics (STAMP). Nutritional counseling followed the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) guidelines and considered the patients’ dietary history, including content and administration method. Motor functions were assessed by validated tests: the Children’s Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND) and the Hammersmith Functional Motor Scale—Expanded (HFMSE). Result The study showed an improvement in HFA, by a change from −0.95 to −0.65 (p = 0.015). Conversely, BMI scores decreased from 0.08 to −0.54 (p = 0.015), while WFH and MUAC showed no significant alterations (p = 0.135, p = 0.307). Following nutritional interventions, HFMSE demonstrated a median increase from 29.5 to 30.5 (p = 0.023). Patients identified as being at high risk for malnutrition based on PYMS and STAMP belonged to the moderate-to-severe malnutrition group (BMI Z-score ≤ −2, p = 0.001). Conclusions Use of screening tools in SMA patients is highly beneficial for the early detection of malnutrition. Future research should highlight the importance of combining nutritional management with nusinersen therapy to potentially alter the disease trajectory, especially in motor and neurological functions.

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Troch, Marlene. "Treatment approaches towards physical activity – malnutrition – cognitive impairment." memo - Magazine of European Medical Oncology 14, no. 2 (June 2021): 129. http://dx.doi.org/10.1007/s12254-021-00704-6.

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Chevalier, Philippe. "Zinc and duration of treatment of severe malnutrition." Lancet 345, no. 8956 (April 1995): 1046–47. http://dx.doi.org/10.1016/s0140-6736(95)90783-1.

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Kronfeld, D. S. "Starvation and malnutrition of horses: recognition and treatment." Journal of Equine Veterinary Science 13, no. 5 (May 1993): 298–304. http://dx.doi.org/10.1016/s0737-0806(07)80253-x.

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Gentile, Maria Gabriella, and Giulia Maria Manna. "Refeeding hypophosphataemia in malnutrition patients: Prevention and treatment." Clinical Nutrition 31, no. 3 (June 2012): 429. http://dx.doi.org/10.1016/j.clnu.2011.11.010.

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Russell, Mary. "We’re Part of the Solution: Malnutrition Prevention, Treatment." Journal of the Academy of Nutrition and Dietetics 118, no. 9 (September 2018): 1569. http://dx.doi.org/10.1016/j.jand.2018.07.003.

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Journal articles on the topic 'Malnutrition – Treatment'

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