Academic literature on the topic 'Malaria vaccine Synthesis'
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Journal articles on the topic "Malaria vaccine Synthesis"
Clemente, Marina, and Mariana G. Corigliano. "Overview of Plant-Made Vaccine Antigens against Malaria." Journal of Biomedicine and Biotechnology 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/206918.
Full textBallou, W. R., J. Blood, T. Chongsuphajaissidhi, D. M. Gordon, D. G. Heppner, D. E. Kyle, C. Luxemburger, et al. "Field trials of an asexual blood stage malaria vaccine: studies of the synthetic peptide polymer SPf66 in Thailand and the analytic plan for a phase IIb efficacy study." Parasitology 110, S1 (March 1995): S25—S36. http://dx.doi.org/10.1017/s0031182000001463.
Full textMoysa, A. A., and E. F. Kolesanova. "Synthetic peptide vaccines." Biomeditsinskaya Khimiya 57, no. 1 (January 2011): 14–30. http://dx.doi.org/10.18097/pbmc20115701104.
Full textOlugbile, S., C. Kulangara, G. Bang, S. Bertholet, E. Suzarte, V. Villard, G. Frank, et al. "Vaccine Potentials of an Intrinsically Unstructured Fragment Derived from the Blood Stage-Associated Plasmodium falciparum Protein PFF0165c." Infection and Immunity 77, no. 12 (September 28, 2009): 5701–9. http://dx.doi.org/10.1128/iai.00652-09.
Full textChandrudu, Saranya, Mariusz Skwarczynski, David Pattinson, Simon H. Apte, Denise L. Doolan, and Istvan Toth. "Synthesis and immunological evaluation of peptide-based vaccine candidates against malaria." Biochemical Compounds 4, no. 1 (2016): 1. http://dx.doi.org/10.7243/2052-9341-4-1.
Full textJoshi, Manju B., Albert A. Gam, Robert A. Boykins, Sanjai Kumar, John Sacci, Stephen L. Hoffman, Hira L. Nakhasi, and Richard T. Kenney. "Immunogenicity of Well-Characterized Synthetic Plasmodium falciparum Multiple Antigen Peptide Conjugates." Infection and Immunity 69, no. 8 (August 1, 2001): 4884–90. http://dx.doi.org/10.1128/iai.69.8.4884-4890.2001.
Full textHewitt, Michael C., Daniel A. Snyder, and Peter H. Seeberger. "Rapid Synthesis of a Glycosylphosphatidylinositol-Based Malaria Vaccine Using Automated Solid-Phase Oligosaccharide Synthesis." Journal of the American Chemical Society 124, no. 45 (November 2002): 13434–36. http://dx.doi.org/10.1021/ja027538k.
Full textKanoi, Bernard N., Hikaru Nagaoka, Masayuki Morita, Takafumi Tsuboi, and Eizo Takashima. "Leveraging the wheat germ cell-free protein synthesis system to accelerate malaria vaccine development." Parasitology International 80 (February 2021): 102224. http://dx.doi.org/10.1016/j.parint.2020.102224.
Full textKronenberger, Thales, Jasmin Lindner, Kamila A. Meissner, Flávia M. Zimbres, Monika A. Coronado, Frank M. Sauer, Isolmar Schettert, and Carsten Wrenger. "Vitamin B6-Dependent Enzymes in the Human Malaria ParasitePlasmodium falciparum: A Druggable Target?" BioMed Research International 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/108516.
Full textPfeiffer, Bernhard, Elisabetta Peduzzi, Kerstin Moehle, Rinaldo Zurbriggen, Reinhard Glück, Gerd Pluschke, and John A. Robinson. "A Virosome-Mimotope Approach to Synthetic Vaccine Design and Optimization: Synthesis, Conformation, and Immune Recognition of a Potential Malaria-Vaccine Candidate." Angewandte Chemie International Edition 42, no. 21 (May 30, 2003): 2368–71. http://dx.doi.org/10.1002/anie.200250348.
Full textDissertations / Theses on the topic "Malaria vaccine Synthesis"
Yepuri, Nageshwar Rao. "The design and synthesis of novel anti-malarial agents." Access electronically, 2004. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20050330.085201/index.html.
Full textHewitt, Michael Charles 1975. "Solution and solid-phase synthesis of potential carbohydrate vaccines for leishmaniasis and malaria." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/27111.
Full textVita.
Includes bibliographical references.
The human disease leishmaniasis afflicts over 20 million people worldwide, and is caused by unicellular protozoan parasites. Cell surface carbohydrates are implicated in immune recognition of the parasite by host macrophages. The synthesis of a unique tetrasaccharide found on the parasite cell surface lipophosphoglycan is described. The synthetic material was used to create two novel immungens that are currently being evaluated in an animal model. New methods were also developed for an automated solid-phase synthesis that took a fraction of the time required for the solution-phase synthesis. Malaria kills over 2 million people per year, and is caused by protozoan parasites of the genus Plasmodium. Much of the morbidity and mortality associated with malaria is thought to be due to a toxin released in the host following red blood cell rupture. A glycosylphosphatidylinositol (GPI) anchor of parasite origin was recently identified, and had the properties of a toxin. The synthesis of a modified version of the malarial GPI both in solution and on solid-phase in an automated fashion is described. The synthetic material was attached to a carrier protein and used to immunize mice, who were substantially protected against all aspects of a subsequent challenge by malarial parasites. A new capping protocol for automated solid-phase synthesis is described. A novel fluorous silyl triflate was used to tag deletion sequences that could then be separated from the desired sequence by filtration through fluorous reverse-phase silica gel. Two trisaccharide sequences were synthesized both with and without fluorous capping to demonstrate the effectiveness of the capping protocol.
by Michael Charles Hewitt.
Ph.D.
Brune, Karl Dietrich. "Engineering modular platforms for rapid vaccine development." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:41d57165-6e7c-4ca7-8025-b5ec31794c8c.
Full textSteinbeis, Fridolin [Verfasser]. "Protective potential and immunological evaluation of synthetic Plasmodium GPI glycoconjugate vaccines against experimental cerebral malaria / Fridolin Steinbeis." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2017. http://d-nb.info/1133492908/34.
Full textBooks on the topic "Malaria vaccine Synthesis"
Visweswara Rao, Pasupuleti, Balam Satheesh Krishna, and Mohammad Saffree Jeffree, eds. Coronaviruses Transmission, Frontliners, Nanotechnology and Economy. UMS Press, 2022. http://dx.doi.org/10.51200/coronavirusesdrraoums2021.
Full textBook chapters on the topic "Malaria vaccine Synthesis"
Stocker, Bridget L., Alexandra Hölemann, and Peter H. Seeberger. "Automated Oligosaccharide Synthesis to Create Vaccines for Malaria and Other Parasites." In ACS Symposium Series, 137–62. Washington, DC: American Chemical Society, 2008. http://dx.doi.org/10.1021/bk-2008-0989.ch007.
Full textSpetzler, J. C., C. Rao, and J. P. Tam. "A novel approach to a synthetic malaria vaccine using the multiple antigen peptide system." In Peptides, 750–52. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_249.
Full textEtlinger, Howard M. "The Use of Recombinant Proteins and Synthetic Peptides in the Development of a Plasmodium Falciparum Malaria Vaccine." In Modern Vaccinology, 341–56. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4899-1450-7_18.
Full textNardin, Elizabeth. "Synthetic Peptides as Malaria Vaccines." In Malaria, 495–540. CRC Press, 1999. http://dx.doi.org/10.1201/b17000-21.
Full text"Synthetic Peptides as Malaria Vaccines." In Malaria, 509–54. CRC Press, 1999. http://dx.doi.org/10.1201/b17000-24.
Full textCorradin, Giampietro, Nora Céspedes, Antonio Verdini, Andrey V. Kajava, Myriam Arévalo-Herrera, and Sócrates Herrera. "Malaria Vaccine Development Using Synthetic Peptides as a Technical Platform." In Synthetic Vaccines, 107–49. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-396548-6.00005-6.
Full textConference papers on the topic "Malaria vaccine Synthesis"
Patarroyo, Manuel Elkin. "Different strategies towards the design of a synthetic subunit malaria vaccine." In Future Aspect in Peptide Chemistry - Ringberg Conference. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199901108.
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