Journal articles on the topic 'Lysosomes'
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Nakae, Isei, Tomoko Fujino, Tetsuo Kobayashi, Ayaka Sasaki, Yorifumi Kikko, Masamitsu Fukuyama, Keiko Gengyo-Ando, Shohei Mitani, Kenji Kontani, and Toshiaki Katada. "The Arf-like GTPase Arl8 Mediates Delivery of Endocytosed Macromolecules to Lysosomes inCaenorhabditis elegans." Molecular Biology of the Cell 21, no. 14 (July 15, 2010): 2434–42. http://dx.doi.org/10.1091/mbc.e09-12-1010.
Full textTrivedi, Purvi C., Jordan J. Bartlett, and Thomas Pulinilkunnil. "Lysosomal Biology and Function: Modern View of Cellular Debris Bin." Cells 9, no. 5 (May 4, 2020): 1131. http://dx.doi.org/10.3390/cells9051131.
Full textAmick, Joseph, Arun Kumar Tharkeshwar, Catherine Amaya,, and Shawn M. Ferguson. "WDR41 supports lysosomal response to changes in amino acid availability." Molecular Biology of the Cell 29, no. 18 (September 2018): 2213–27. http://dx.doi.org/10.1091/mbc.e17-12-0703.
Full textBonet-Ponce, Luis, Alexandra Beilina, Chad D. Williamson, Eric Lindberg, Jillian H. Kluss, Sara Saez-Atienzar, Natalie Landeck, et al. "LRRK2 mediates tubulation and vesicle sorting from lysosomes." Science Advances 6, no. 46 (November 2020): eabb2454. http://dx.doi.org/10.1126/sciadv.abb2454.
Full textBakker, A. C., P. Webster, W. A. Jacob, and N. W. Andrews. "Homotypic fusion between aggregated lysosomes triggered by elevated [Ca2+]i in fibroblasts." Journal of Cell Science 110, no. 18 (September 15, 1997): 2227–38. http://dx.doi.org/10.1242/jcs.110.18.2227.
Full textXu, Miao, Ke Liu, Manju Swaroop, Wei Sun, Seameen J. Dehdashti, John C. McKew, and Wei Zheng. "A Phenotypic Compound Screening Assay for Lysosomal Storage Diseases." Journal of Biomolecular Screening 19, no. 1 (August 27, 2013): 168–75. http://dx.doi.org/10.1177/1087057113501197.
Full textCuervo, A. M., E. Knecht, S. R. Terlecky, and J. F. Dice. "Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation." American Journal of Physiology-Cell Physiology 269, no. 5 (November 1, 1995): C1200—C1208. http://dx.doi.org/10.1152/ajpcell.1995.269.5.c1200.
Full textLiu, Ji, Wennan Lu, Sonia Guha, Gabriel C. Baltazar, Erin E. Coffey, Alan M. Laties, Ronald C. Rubenstein, William W. Reenstra, and Claire H. Mitchell. "Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells." American Journal of Physiology-Cell Physiology 303, no. 2 (July 15, 2012): C160—C169. http://dx.doi.org/10.1152/ajpcell.00278.2011.
Full textAlquier, C., P. Guenin, Y. Munari-Silem, C. Audebet, and B. Rousset. "Isolation of pig thyroid lysosomes. Biochemical and morphological characterization." Biochemical Journal 232, no. 2 (December 1, 1985): 529–37. http://dx.doi.org/10.1042/bj2320529.
Full textZeng, Wenping, Canjun Li, Ruikun Wu, Xingguo Yang, Qingyan Wang, Bingqian Lin, Yanan Wei, et al. "Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta." PLOS Biology 22, no. 4 (April 23, 2024): e3002591. http://dx.doi.org/10.1371/journal.pbio.3002591.
Full textPeng, Wesley, Yvette C. Wong, and Dimitri Krainc. "Mitochondria-lysosome contacts regulate mitochondrial Ca2+dynamics via lysosomal TRPML1." Proceedings of the National Academy of Sciences 117, no. 32 (July 23, 2020): 19266–75. http://dx.doi.org/10.1073/pnas.2003236117.
Full textTan, Sin-Lih, Muruj Barri, Peace Atakpa-Adaji, Colin W. Taylor, Ewan St. John Smith, and Ruth D. Murrell-Lagnado. "P2X4 Receptors Mediate Ca2+ Release from Lysosomes in Response to Stimulation of P2X7 and H1 Histamine Receptors." International Journal of Molecular Sciences 22, no. 19 (September 28, 2021): 10492. http://dx.doi.org/10.3390/ijms221910492.
Full textWang, Meng. "LYSOSOMAL SIGNALS IN LONGEVITY REGULATION ACROSS THE SCALE." Innovation in Aging 7, Supplement_1 (December 1, 2023): 340. http://dx.doi.org/10.1093/geroni/igad104.1133.
Full textHernandez, Grace A., Thuy Nguyen, Matthew Luy, Alexander Li, Longhui Qiu, Joseph D. Mancias, and Rushika M. Perera. "Abstract B052: Defining the lysosome proteome during tumor evolution." Cancer Research 84, no. 2_Supplement (January 16, 2024): B052. http://dx.doi.org/10.1158/1538-7445.panca2023-b052.
Full textPierga, Alexandre, Raphaël Matusiak, Margaux Cauhapé, Julien Branchu, Lydia Danglot, Maxime Boutry, and Frédéric Darios. "Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1." PLOS Biology 21, no. 10 (October 23, 2023): e3002337. http://dx.doi.org/10.1371/journal.pbio.3002337.
Full textHipolito, Victoria E. B., Jacqueline A. Diaz, Kristofferson V. Tandoc, Amra Saric, Ivan Toposiviric, and Roberto J. Botelho. "mTOR induces lysosome expansion by selective translation of lysosomal transcripts during phagocyte activation." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 170.19. http://dx.doi.org/10.4049/jimmunol.200.supp.170.19.
Full textOliver, C., R. Dromy, and T. K. Hart. "Density gradient separation of two populations of lysosomes from rat parotid acinar cells." Journal of Histochemistry & Cytochemistry 37, no. 11 (November 1989): 1645–52. http://dx.doi.org/10.1177/37.11.2553801.
Full textWerneburg, Nathan W., M. Eugenia Guicciardi, Steven F. Bronk, and Gregory J. Gores. "Tumor necrosis factor-α-associated lysosomal permeabilization is cathepsin B dependent." American Journal of Physiology-Gastrointestinal and Liver Physiology 283, no. 4 (October 1, 2002): G947—G956. http://dx.doi.org/10.1152/ajpgi.00151.2002.
Full textChristensen, Kenneth A., Jesse T. Myers, and Joel A. Swanson. "pH-dependent regulation of lysosomal calcium in macrophages." Journal of Cell Science 115, no. 3 (February 1, 2002): 599–607. http://dx.doi.org/10.1242/jcs.115.3.599.
Full textNguyen, Van-Nghia, and Haidong Li. "Recent Development of Lysosome-Targeted Organic Fluorescent Probes for Reactive Oxygen Species." Molecules 28, no. 18 (September 15, 2023): 6650. http://dx.doi.org/10.3390/molecules28186650.
Full textJerome, W. Gray, and Patricia G. Yancey. "The Role of Microscopy in Understanding Atherosclerotic Lysosomal Lipid Metabolism." Microscopy and Microanalysis 9, no. 1 (January 31, 2003): 54–67. http://dx.doi.org/10.1017/s1431927603030010.
Full textLi, Chenghao, Zhuo Zheng, and Meishan Jin. "The Significance of Lysosome in the Diagnosis and Subclassification of Alzheimer’s Disease." Science of Advanced Materials 15, no. 2 (February 1, 2023): 233–42. http://dx.doi.org/10.1166/sam.2023.4441.
Full textFlannery, Andrew R., Cecilia Czibener, and Norma W. Andrews. "Palmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomes." Journal of Cell Biology 191, no. 3 (November 1, 2010): 599–613. http://dx.doi.org/10.1083/jcb.201003021.
Full textEbner, Michael, Philipp Alexander Koch, and Volker Haucke. "Phosphoinositides in the control of lysosome function and homeostasis." Biochemical Society Transactions 47, no. 4 (August 5, 2019): 1173–85. http://dx.doi.org/10.1042/bst20190158.
Full textWilliams, M. A., and M. Fukuda. "Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail." Journal of Cell Biology 111, no. 3 (September 1, 1990): 955–66. http://dx.doi.org/10.1083/jcb.111.3.955.
Full textNguyen, Thuy T. P., Grace A. Hernandez, Gilles Rademaker, Matthew Luy, Alexander Li, Longhui Qiu, Joao A. Paulo, Rushika M. Perera, and Joseph D. Mancias. "Abstract A082: Defining the lysosome proteome during pancreatic cancer tumor evolution and metastasis." Cancer Research 84, no. 17_Supplement_2 (September 15, 2024): A082. http://dx.doi.org/10.1158/1538-7445.pancreatic24-a082.
Full textBoonen, Marielle, Isabelle Hamer, Muriel Boussac, Anne-Françoise Delsaute, Bruno Flamion, Jérôme Garin, and Michel Jadot. "Intracellular localization of p40, a protein identified in a preparation of lysosomal membranes." Biochemical Journal 395, no. 1 (March 15, 2006): 39–47. http://dx.doi.org/10.1042/bj20051647.
Full textAndrade, Luciana O., and Norma W. Andrews. "Lysosomal Fusion Is Essential for the Retention of Trypanosoma cruzi Inside Host Cells." Journal of Experimental Medicine 200, no. 9 (November 1, 2004): 1135–43. http://dx.doi.org/10.1084/jem.20041408.
Full textDomagala, Antoni, Klaudyna Fidyt, Malgorzata Bobrowicz, Joanna Stachura, Kacper Szczygiel, and Malgorzata Firczuk. "Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer Strategy." International Journal of Molecular Sciences 19, no. 8 (August 1, 2018): 2256. http://dx.doi.org/10.3390/ijms19082256.
Full textDielschneider, Rebecca, Hannah Eisenstat, James B. Johnston, and Spencer B. Gibson. "Lysosome Membrane Permeabilization Causes Cell Death in Primary Chronic Lymphocytic Leukemia Cells." Blood 124, no. 21 (December 6, 2014): 930. http://dx.doi.org/10.1182/blood.v124.21.930.930.
Full textKuk, Myeong Uk, Yun Haeng Lee, Jae Won Kim, Su Young Hwang, Joon Tae Park, and Sang Chul Park. "Potential Treatment of Lysosomal Storage Disease through Modulation of the Mitochondrial—Lysosomal Axis." Cells 10, no. 2 (February 17, 2021): 420. http://dx.doi.org/10.3390/cells10020420.
Full textSchulze, Ryan J., Eugene W. Krueger, Shaun G. Weller, Katherine M. Johnson, Carol A. Casey, Micah B. Schott, and Mark A. McNiven. "Direct lysosome-based autophagy of lipid droplets in hepatocytes." Proceedings of the National Academy of Sciences 117, no. 51 (December 7, 2020): 32443–52. http://dx.doi.org/10.1073/pnas.2011442117.
Full textRodríguez, Ana, Paul Webster, Javier Ortego, and Norma W. Andrews. "Lysosomes Behave as Ca2+-regulated Exocytic Vesicles in Fibroblasts and Epithelial Cells." Journal of Cell Biology 137, no. 1 (April 7, 1997): 93–104. http://dx.doi.org/10.1083/jcb.137.1.93.
Full textBurlando, Bruno, Barbara Marchi, Isabella Panfoli, and Aldo Viarengo. "Essential role of Ca2+-dependent phospholipase A2in estradiol-induced lysosome activation." American Journal of Physiology-Cell Physiology 283, no. 5 (November 1, 2002): C1461—C1468. http://dx.doi.org/10.1152/ajpcell.00429.2001.
Full textJerome, W. Gray, Brian E. Cox, Evelyn E. Griffin, and Jody C. Ullery. "Lysosomal Cholesterol Accumulation Inhibits Subsequent Hydrolysis of Lipoprotein Cholesteryl Ester." Microscopy and Microanalysis 14, no. 2 (March 3, 2008): 138–49. http://dx.doi.org/10.1017/s1431927608080069.
Full textWang, Tuanlao, Ka Khuen Wong, and Wanjin Hong. "A Unique Region of RILP Distinguishes It from Its Related Proteins in Its Regulation of Lysosomal Morphology and Interaction with Rab7 and Rab34." Molecular Biology of the Cell 15, no. 2 (February 2004): 815–26. http://dx.doi.org/10.1091/mbc.e03-06-0413.
Full textColbaugh, P. A., M. Stookey, and R. K. Draper. "Impaired lysosomes in a temperature-sensitive mutant of Chinese hamster ovary cells." Journal of Cell Biology 108, no. 6 (June 1, 1989): 2211–19. http://dx.doi.org/10.1083/jcb.108.6.2211.
Full textEurell, Thomas E., Jo Ann C. Eurell, David J. Schaeffer, David R. Mattie, and Carl L. Alden. "Lysosomal Changes in Renal Proximal Tubular Epithelial Cells of Male Sprague Dawley Rats following Decalin Exposure." Toxicologic Pathology 18, no. 4 (November 1990): 637–42. http://dx.doi.org/10.1177/01926233900184p201.
Full textSelmi, S., and B. Rousset. "Identification of two subpopulations of thyroid lysosomes: relation to the thyroglobulin proteolytic pathway." Biochemical Journal 253, no. 2 (July 15, 1988): 523–32. http://dx.doi.org/10.1042/bj2530523.
Full textSaric, Amra, Victoria E. B. Hipolito, Jason G. Kay, Johnathan Canton, Costin N. Antonescu, and Roberto J. Botelho. "mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells." Molecular Biology of the Cell 27, no. 2 (January 15, 2016): 321–33. http://dx.doi.org/10.1091/mbc.e15-05-0272.
Full textJing, Yongwei, Masahiko Kobayashi, and Atsushi Hirao. "Abstract LB258: Therapeutic advantage of targeting lysosome as signaling hub for metabolic conditions in malignant gliomas." Cancer Research 83, no. 8_Supplement (April 14, 2023): LB258. http://dx.doi.org/10.1158/1538-7445.am2023-lb258.
Full textSwanson, J., E. Burke, and S. C. Silverstein. "Tubular lysosomes accompany stimulated pinocytosis in macrophages." Journal of Cell Biology 104, no. 5 (May 1, 1987): 1217–22. http://dx.doi.org/10.1083/jcb.104.5.1217.
Full textBright, N. A., B. J. Reaves, B. M. Mullock, and J. P. Luzio. "Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles." Journal of Cell Science 110, no. 17 (September 1, 1997): 2027–40. http://dx.doi.org/10.1242/jcs.110.17.2027.
Full textBeauvarlet, Jennifer, Rabindra Nath Das, Karla Alvarez-Valadez, Isabelle Martins, Alexandra Muller, Elodie Darbo, Elodie Richard, et al. "Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells." Cancers 12, no. 6 (June 18, 2020): 1621. http://dx.doi.org/10.3390/cancers12061621.
Full textPerou, C. M., and J. Kaplan. "Chediak-Higashi syndrome is not due to a defect in microtubule-based lysosomal mobility." Journal of Cell Science 106, no. 1 (September 1, 1993): 99–107. http://dx.doi.org/10.1242/jcs.106.1.99.
Full textFolick, Andrew, Holly D. Oakley, Yong Yu, Eric H. Armstrong, Manju Kumari, Lucas Sanor, David D. Moore, Eric A. Ortlund, Rudolf Zechner, and Meng C. Wang. "Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans." Science 347, no. 6217 (January 1, 2015): 83–86. http://dx.doi.org/10.1126/science.1258857.
Full textJu, Xiangwu, Yiwu Yan, Qiang Liu, Ning Li, Miaomiao Sheng, Lifang Zhang, Xiao Li, et al. "Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture." Journal of Virology 89, no. 20 (August 5, 2015): 10347–58. http://dx.doi.org/10.1128/jvi.01411-15.
Full textGowrishankar, Swetha, and Shawn M. Ferguson. "Lysosomes relax in the cellular suburbs." Journal of Cell Biology 212, no. 6 (March 14, 2016): 617–19. http://dx.doi.org/10.1083/jcb.201602082.
Full textLuzio, J. Paul, Michael D. J. Parkinson, Sally R. Gray, and Nicholas A. Bright. "The delivery of endocytosed cargo to lysosomes." Biochemical Society Transactions 37, no. 5 (September 21, 2009): 1019–21. http://dx.doi.org/10.1042/bst0371019.
Full textKe, Po-Yuan. "Molecular Mechanism of Autophagosome–Lysosome Fusion in Mammalian Cells." Cells 13, no. 6 (March 13, 2024): 500. http://dx.doi.org/10.3390/cells13060500.
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