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1

L, Kripke Margaret, Frost Philip 1940-, and M.D. Anderson Hospital and Tumor Institute., eds. Immunology and cancer. Austin: Published for the University of Texas System Cancer Center, M.D. Anderson Hospital and Tumor Institute, Houston, Tex. by the University of Texas Press, 1986.

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2

Alexander, Michael A. Immune-based cancer treatment: The T lymphocyte response. Boca Raton, FL: CRC Press, 2011.

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3

Alexander, Michael A. Immune-based cancer treatment: The T lymphocyte response. Boca Raton, FL: CRC Press, 2011.

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4

Clark, Lambert W., Giannotti B, Vloten W. A. van, North Atlantic Treaty Organization. Scientific Affairs Division., and NATO Advanced Research Workshop on Basic Mechanisms of Physiologic and Aberrant Lymphoproliferation in the Skin (1991 : San Miniato, Italy), eds. Basic mechanisms of physiologic and aberrant lymphoproliferation in the skin. New York: Plenum Press, 1994.

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5

Symposium, Takamatsu no Miya Hi Gan Kenkyū Kikin International. Retroviruses in human lymphoma/leukemia: Proceedings of the 15th International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, 1984. Tokyo: Japan Scientific Societies Press, 1985.

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6

1944-, Finke James H., and Bukowski Ronald M, eds. Cancer immunotherapy at the crossroads: How tumors evade immunity and what can be done. Totowa, N.J: Humana Press, 2004.

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7

1944-, Finke James H., and Bukowski Ronald M, eds. Cancer immunotherapy at the crossroads: How tumors evade immunity and what can be done. Totowa, N.J: Humana Press, 2004.

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8

Burkhard, Ludewig, and Hoffmann Matthias W, eds. Adoptive immunotherapy: Methods and protocols. Totowa, N.J: Humana Press, 2005.

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9

Immunotherapy of cancer with sensitized T lymphocytes. Austin: R.G. Landes, 1994.

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10

Medin, Jeffrey, and Daniel Fowler. Experimental and Applied Immunotherapy. Springer, 2011.

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11

Medin, Jeffrey, and Daniel Fowler. Experimental and Applied Immunotherapy. Humana, 2014.

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12

Cellular Therapy Of Cancer. World Scientific Publishing Company, 2010.

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13

(Editor), James H. Finke, and Ronald M. Bukowski (Editor), eds. Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology). Humana Press, 2003.

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14

McMichael, A. J. A New Look at Tumour Immunology (Cancer Surveys Series Vol 13) (Cancer Surveys Series Vol 13). Cold Spring Harbor Laboratory Pr, 1992.

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15

(Editor), K. Kikuchi, B. J. Van Den Eynde (Editor), and N. Sato (Editor), eds. Recent Advances of Human Tumor Immunology and Immunotherapy (Gann Monograph on Cancer Research). Not Avail, 1999.

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16

Hawkins, Robert E. Cellular Therapy of Cancer: Development of Gene Therapy Based Approaches. World Scientific Publishing Co Pte Ltd, 2014.

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17

Ludewig, Burkhard, and Matthias W. Hoffmann. Adoptive Immunotherapy: Methods and Protocols. Humana Press, 2010.

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18

Adoptive immunotherapy: Methods and protocols. Totowa, NJ: Humana Press, 2004.

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19

Moerdler, Scott, and Xingxing Zang. PD-1/PDL-1 Inhibitors as Immunotherapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0010.

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Abstract:
Programmed death 1 (PD-1), a member of the B7-CD28 immunoglobulin superfamily, and its ligands PD-L1/PD-L2 inhibit T-cell activation. They also play a key role in the tumor microenvironment, allowing for cancer immune escape. PD-1 is induced on a variety of immune cells, including tumor-infiltrating lymphocytes (TILs), while PD-L1 is found on many types of solid tumors including ovarian cancer and some TILs. The use of immunocheckpoint inhibitors like anti-PD-1 and anti-PD-L1 therapies has been shown to reactivate the immune system to attack tumor cells. Ovarian cancers have been shown to be responsive to anti-PD-1 and anti-PD-L1 therapies, though immunocheckpoint inhibitors are not enough. Current research is evaluating combination therapies to improve response rates.
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