Relevant bibliographies by topics / Lymphocyte

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Lymphocyte'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 April 2025

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Journal articles on the topic "Lymphocyte"

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Chen, Lin-Ying, Julia Y. S. Tsang, Yun-Bi Ni, Siu-Ki Chan, Kui-Fat Chan, Sheng Zhang, and Gary M. Tse. "Lymphocyte subsets contribute to the degree of lobulitis and ductitis in sclerosing lymphocytic lobulitis of the breast." Journal of Clinical Pathology 69, no. 6 (November 18, 2015): 527–32. http://dx.doi.org/10.1136/jclinpath-2015-203334.

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AimsSclerosing lymphocytic lobulitis (SLL) of the breast is characterised by lymphocytic lobulitis, ductitis, vasculitis and dense keloidal fibrosis with epithelioid fibroblasts. However, the subsets of the infiltrating lymphocytes and their contribution to disease progression have not been fully explored.MethodsCD20, CD3, CD4, CD8 and regulatory T (Treg) lymphocytes were evaluated in the epithelial and vascular areas in SLL. The relationship between the lymphocyte subset in different regions and the degree of inflammation was analysed.ResultsLymphocytic infiltration was mainly located in peri-lobular, peri-ductal and peri-vascular areas. No significant differences between CD20 and CD3 lymphocytes were found in peri-epithelial areas. However, there were more intra-ductal/lobular epithelial CD3 than CD20 lymphocytes (p<0.001). For T lymphocyte subsets, more CD4 than CD8 lymphocytes were found in the peri-lobular/vascular regions (p≤0.026); but an opposite trend was seen in the intra-ductal/lobular regions (p<0.001). In the peri-lobular/vascular regions, generally, different lymphocyte subsets correlated with each other. Interestingly, in the peri-ductal region, only CD4 lymphocytes showed significant correlations with all other subsets (p≤0.020). Regarding their relationship with the degree of inflammation, significant positive correlations were observed for all subsets in peri-vascular/lobular regions (p≤0.045). Only regulatory T cells, but not the others, at the peri-ductal region showed significant correlation with the degree of inflammation at all three regions (p≤0.014).ConclusionsIn addition to B lymphocyte subsets, T lymphocyte subsets could be involved differently in SLL. CD4 lymphocytes may have a pivotal role in recruiting other subsets to the inflamed site, and triggered the cascade of inflammatory changes resulting in fibrosis.
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Winther, Birgit, Donald J. Innes, John Bratsch, and Frederick G. Hayden. "Lymphocyte Subsets in the Nasal Mucosa and Peripheral Blood during Experimental Rhinovirus Infection." American Journal of Rhinology 6, no. 4 (July 1992): 149–56. http://dx.doi.org/10.2500/105065892781874621.

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The local cellular response during rhinovirus infection was studied with immunohistochemical staining of lymphocyte subpopulations in the lamina propria of the nasal mucosa (inferior turbinate) in 25 biopsies from volunteers with experimental rhinovirus colds and compared with biopsies from healthy volunteers. Biopsies from rhinovirus infected volunteers, taken either in the early phase of the infection (days 3 and 5) or during convalescence (day 14) were evaluated in a semiquantitative fashion for degree of infiltration. Lymphocyte subpopulations also were counted on coded specimens. During experimental rhinovirus infection, no change could be observed in the overall degree of lymphocytic infiltration or in the numbers of T and B lymphocytes compared with control specimens. The overall degree of lymphocyte infiltration in the nasal mucosa was mild to moderate and consisted principally of T lymphocytes and only a few scattered B lymphocytes. Few natural killer lymphocytes were seen. These findings are similar to those in normal nasal mucosa and in contrast to the findings after topical application of recombinant interferon, which often results in a heavy lymphocyte infiltration. Lymphocyte subpopulation in the peripheral blood did not change when compared with prechallenge values in nine rhinovirus-infected volunteers.
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Park, Kenneth G. M., Steven D. Heys, Margaret A. McNurlan, Peter J. Garlick, and Oleg Eremin. "Lymphocyte Protein Synthesis In Vivo: a Measure of Activation." Clinical Science 86, no. 6 (June 1, 1994): 671–75. http://dx.doi.org/10.1042/cs0860671.

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1. The ‘flooding’ dose technique was used to measure rates of lymphocyte protein synthesis after infusion of [1-13C]leucine (20 atoms% enrichment, 4 g/70 kg body weight). Lymphocyte protein synthesis was measured in healthy subjects and in patients with metastatic colorectal cancer before and during infusion of recombinant interleukin-2. Rates of protein synthesis were compared with thymidine uptake in vitro and phenotypic analysis of lymphocytes. 2. The median rate of lymphocyte protein synthesis in four healthy subjects was 9% (range 7.2–11.4%/day) and in seven patients with colorectal cancer was 6.4% (range 4.2–8.2%/day). After recombinant interleukin-2 treatment the median rate of lymphocyte protein synthesis was 27.8% (range 25.2–33.7%/day). 3. The increased rates of lymphocyte protein synthesis in vivo, after recombinant interleukin-2 infusion, corresponded with increased rates of thymidine uptake and changes in the phenotypic expression of lymphocytes, but these were less consistent than the measured rates of protein synthesis. 4. It is concluded that lymphocyte activation is accompanied by a marked increase in lymphocytic protein synthesis which may have important implications for whole body protein metabolism. Furthermore, measurement of lymphocyte protein synthesis may provide a determination of lymphocyte activation in vivo.
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Choccalingam, Chidambharam. "Volume, conductance, and scatter parameters of neoplastic and nonneoplastic lymphocytes using Coulter LH780." Journal of Laboratory Physicians 10, no. 01 (January 2018): 085–88. http://dx.doi.org/10.4103/jlp.jlp_65_17.

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Abstract PURPOSE: Automated hematology analyzers yield a complete hematological profile including a complete blood count and a differential white blood cell count. The differential count is based on analyses of three parameters, namely, volume, conductance, and scatter (VCS). We aimed to evaluate the VCS parameters, histograms, and scatterplots of neoplastic and nonneoplastic lymphocytes. MATERIAL AND METHODS: Patients were grouped into four categories, namely, acute lymphoblastic leukemia (ALL), chronic systemic disorders, chronic lymphocytic leukemia (CLL), and acute viral disease. Lymphocytes from all four groups were compared with lymphocytes from normal participants. RESULTS AND CONCLUSIONS: The histogram for acute viral disease showed a trough at T1, which was slightly obliterated, and the F1 curve mildly extended to the right. The T1 for ALL was replaced with a peak at >40% of the preset limit. The F1 peak was shifted to left for CLL. The scatterplot for viral disease showed lymphocytes extending to the variant lymphocyte window. The lymphocytes of ALL extended to the blast window, with both increase in volume and mild increase in scatter. The lymphocytes in CLL were smaller and located below the normal lymphocyte region. Mean lymphocyte volume was significantly increased in ALL and was significantly decreased in CLL. Mean lymphocyte conductance was significantly increased in CLL and significantly decreased in both acute viral disease and ALL. Mean lymphocyte scatter was significantly decreased in acute viral disease and significantly increased in ALL.
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Li, Jianxu, Peng Guo, Masayuki Hirano, Brantley Herrin, and Max Cooper. "Cellular and molecular characterization of hagfish VLR-based adaptive immune system (VET2P.1043)." Journal of Immunology 192, no. 1_Supplement (May 1, 2014): 207.15. http://dx.doi.org/10.4049/jimmunol.192.supp.207.15.

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Abstract Jawless vertebrates have an alternative adaptive immune system in which variable lymphocyte receptors (VLR) are somatically diversified through recombinatorial assembly of leucine-rich repeat cassettes during lymphocyte development. Three VLR loci (VLRA, VLRB, and VLRC) have been defined in lampreys and each is expressed by a distinct lymphocyte population. Lamprey VLRA and VLRC are expressed by T-like lineages of lymphocytes, whereas VLRB is expressed by a B-like lineage of lymphocytes, much like αβ T, γδ T and B cells in jawed vertebrates. Recently we have revised the nomenclature for the hagfish VLRs by defining a third VLR gene. Here, monoclonal and polyclonal antibodies were generated against invariant residues of hagfish VLRA, VLRB and VLRC and these were used to identify VLR-bearing lymphocytes and their products. We found that hagfish VLRA, VLRB and VLRC are expressed by three separate lymphocyte populations. Size-exclusion chromatography and western blot analysis indicated that multivalent VLRB proteins are released into the circulation, which suggests that hagfish VLRB+ cells are B-cell like. In contrast, neither VLRA nor VLRC was detectable in the plasma, supporting the hypothesis that these two lymphocyte populations are T-cell like. The demonstration of three lymphocyte populations in both lampreys and hagfish suggests that this tripartite lymphocytic differentiation program already existed in a common ancestor of the two cyclostome lineages around 480 Mya.
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Schimpff, R. M., and A. M. Repellin. "In vitro effect of human growth hormone on lymphocyte transformation and lymphocyte growth factors secretion." Acta Endocrinologica 120, no. 6 (June 1989): 745–52. http://dx.doi.org/10.1530/acta.0.1200745.

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Abstract. Cultures of human blood peripheral lymphocytes were performed in the presence or absence of human growth hormone, and also of phytohemagglutinin and normal human serum 10%. After incubation for 48 h, the supernatants were tested for their ability to promote the uptake of [3H]thymidine into lectin-activated lymphocytes. Supernatants from lymphocyte-free control samples, treated in the same manner, were assayed under the same experimental conditions. Variance analysis of the different dose-response relationships was performed. The results of these in vitro experiments confirm that physiological levels of GH inhibit the lectin-induced lymphoproliferation and that lymphocytes secrete an 'activity' able to stimulate the incorporation of [3H]thymidine into lectin activated lymphocytes. Furthermore we show that: 1) Secretion of this lymphocyte-stimulating activity is increased by physiological levels of GH; 2) This lymphocytic secretion is not radioimmunoassayable IGF-I; 3) Using fast protein liquid chromatography (FPLC), this activity appears in fractions with various molecular weights.
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Silverman, David A., and Dennis J. Chapron. "Lymphopenic Effect of Carbamazepine in a Patient with Chronic Lymphocytic Leukemia." Annals of Pharmacotherapy 29, no. 9 (September 1995): 865–67. http://dx.doi.org/10.1177/106002809502900906.

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Objective: To report a dramatic and reproducible suppressive effect of carbamazepine on circulating lymphocytes in an elderly woman with chronic lymphocytic leukemia. Case Summary: An elderly woman taking phenytoin for a stroke-associated seizure disorder had lymphocyte count of 28 800 × 106 cells/L. Speculating an unusual lymphadenopathic effect of the phenytoin therapy, carbamazepine therapy was substituted. After 15 weeks of carbamazepine treatment, the lymphocyte count declined to 3200 × 106 cells/L. Because of severe diarrhea, carbamazepine therapy was stopped and phenytoin therapy was reinstituted. At the end of 4 months of phenytoin treatment, the lymphocyte count had increased to 23 200 × 106 cells/L. Phenytoin therapy was discontinued and carbamazepine therapy was begun. The lymphocyte count decreased to 10 700 × 106 cells/L. Severe diarrhea recurred and phenytoin treatment was reinstituted. Over 12 days the lymphocyte count increased to 28 900 × 106 cells/L. Phenytoin therapy was stopped and valproic acid therapy was started. The lymphocyte count continued to increase during valproic acid therapy, reaching a peak of 114 300 × 106 cells/L. Discussion: In this patient with chronic lymphocytic leukemia, carbamazepine therapy had a significant and reproducible lymphopenic effect that was readily reversible upon discontinuation of the drug. Unfortunately, this effect was associated with severe diarrhea, preventing further attempts at exploiting this potentially beneficial action. Conclusions: Carbamazepine had a reproducible suppressive effect on lymphocyte counts in an elderly patient with chronic lymphocytic leukemia. This unique observation raises the possibility that carbamazepine therapy may have a useful effect in patients with chronic lymphocytic leukemia.
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Spain, B. A., D. M. Soliman, R. A. Sidner, and H. L. Twigg. "Enhanced proliferation and IL-2 secretion by lung lymphocytes from HIV-infected subjects." American Journal of Physiology-Lung Cellular and Molecular Physiology 269, no. 4 (October 1, 1995): L498—L506. http://dx.doi.org/10.1152/ajplung.1995.269.4.l498.

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Human immunodeficiency virus (HIV)-positive patients frequently develop a CD3+/CD8+ cytotoxic T cell lymphocytic alveolitis. This could occur through in situ expansion of lung lymphocytes. We evaluated lung and blood lymphocyte proliferation in asymptomatic HIV-infected individuals by measuring spontaneous and cytokine-induced tritiated thymidine incorporation. Interleukin (IL)-2 and IL-4 secretion was determined with the use of enzyme-linked immunosorbent assay, Western blotting, and immunoprecipitation techniques. Spontaneous proliferation by lung lymphocytes from HIV-positive patients was significantly greater than that of normal volunteers. Proliferation was confined to the CD8+ lymphocyte subset. Over time, spontaneous proliferation declined unless autologous alveolar macrophages (AM) were added, suggesting AM were providing additional stimulatory signals to lung lymphocytes. Lung and blood lymphocytes proliferated in response to IL-2 but not IL-4. Lymphocytes in HIV-infected lung spontaneously produced and secreted more IL-2 than either normal lung lymphocytes or autologous blood lymphocytes. IL-4 production was not detectable in either group. These findings support the hypothesis that lymphocytic alveolitis in asymptomatic HIV-positive patients results from IL-2-dependent in situ proliferation of CD3+/CD8+ cytotoxic T cells.
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Todorović, Jasna, Marko Dinčić, Jelena Nešović Ostojić, Ivan Zaletel, Srdjan Lopičić, Duško Dundjerović, Svetislav Tatić, et al. "Differences in Chromatin Texture and Nuclear Fractal Dimension Between Hashimoto's and Lymphocytic Thyroiditis Lymphocytes." Microscopy and Microanalysis 25, no. 3 (February 28, 2019): 762–68. http://dx.doi.org/10.1017/s1431927619000163.

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AbstractPrevious evidence suggested that lymphocytic thyroiditis (LT) was a variant of Hashimoto's thyroiditis (HT), thus the aim of the current study is to quantify structural changes in histological specimens taken from HT and LT patients. A total of 600 images containing a single lymphocyte nucleus (300 nuclei per group) were obtained from 20 patients with HT and LT. In order to quantify changes in the nuclear architecture of investigated lymphocytes, the fractal dimension (FD) and some gray-level co-occurrence matrix texture parameters (angular second moment, inverse difference moment, contrast, entropy, and correlation) were calculated for each nucleus. A statistically significant difference in the FD of the “binary-outlined” nucleus and that of the corresponding “black-and-white” nucleus was detected between HT and LT lymphocyte nuclei. In addition, there was also a statistically significant difference in contrast and correlation between HT and LT lymphocyte nuclei. In conclusion, the results of this study suggested that there was a difference in structural complexity between investigated lymphocyte nuclei; additionally, LT lymphocytes possessed probably more complex texture and larger variations as well as more asymmetrical nuclei compared with HT lymphocytes. Accordingly, these findings indicate that LT is probably not a variant of HT; however, more complex studies are necessary to estimate differences between these types of thyroiditis.
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Wiley, J. S., J. R. Chen, G. P. Jamieson, and P. J. Thurlow. "Agonists for endothelial P2 purinoceptors trigger a signalling pathway producing Ca2+ responses in lymphocytes adherent to endothelial cells." Biochemical Journal 311, no. 2 (October 15, 1995): 589–94. http://dx.doi.org/10.1042/bj3110589.

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Recirculation of lymphocytes through the body involves their frequent adhesion to endothelial cells but little is known of the signalling pathways between these two cell types. Lymphocytes from patients with chronic lymphocytic leukaemia were loaded with the Ca(2+)-sensitive indicator, fura 2, and allowed to adhere to either glass or monolayers of human umbilical-vein endothelial cells. Addition of ATP or UTP (1-10 microM) to the superfusate produced a transient rise in cytosolic Ca2+ concentration in the lymphocytes adherent to endothelium (24 of 35 cells). In contrast, ATP or UTP (1-10 microM) had no effect on the cytosolic Ca2+ of lymphocytes attached to glass. As the only lymphocyte receptor for ATP (P2Z class) requires higher ATP concentrations (> 50 microM) for Ca2+ influx and is unresponsive to UTP, the involvement of a lymphocyte P2Z purinoceptor is unlikely. Various agonists including ATP, UTP, 2-methylthioATP, ADP and histamine all stimulated increases in endothelial cytosolic Ca2+ but only ATP and UTP (both agonists for endothelial P2U purinoceptors) triggered Ca2+ transients in adherent lymphocytes. Removal of extracellular Ca2+ did not abolish the ATP-induced rise in cytosolic Ca2+ concentration in lymphocytes adherent to endothelial cells. These findings show that stimulation of endothelial P2U purinoceptors triggers an endothelial-lymphocyte signalling pathway which releases internal Ca2+ in adherent lymphocytes.
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Dissertations / Theses on the topic "Lymphocyte"

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Culley, Donald A. "Recognition of carbohydrates by T lymphocytes in lymphocyte activation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0022/NQ50137.pdf.

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Culley, Donald A. "Recognition of carbohyrates by T lymphocytes in lymphocyte activation." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35686.

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The purpose of this investigation was to elucidate the role of the oligosaccharides of Class II MHC glycoproteins in allostimulation. Plasma membranes (PM) from the Daudi cell line were chemically deglycosylated using anhydrous hydrogen fluoride (HF). Subsequently, native and deglycosylated (dgl) Class II MHC molecules were affinity purified from their respective PM and inserted into the PM of peripheral blood leukocytes (PBL) which were used as stimulators in the mixed leukocyte reaction (MLR). Stimulator and responder cells were from the same donor. Both forms of the antigen were found to elicit a proliferative and cytolytic (CML) response but the dgl antigen did so to a lesser extent. Thus, it seemed as though the oligosaccharide side chains of Class II MHC molecules may not be required for allostimulation. A similar reduction in the cytolytic response was obtained when effector cells generated by the native antigen were used against targets that were stripped of N-linked oligosaccharides by tunicamycin (TM) pretreatment. Twenty-four clones were raised against the native antigen. Three clones gave proliferative responses only to the native antigen while two clones responded equally to both native and dgl antigen. In CML studies the three clones lysed normal targets but failed to lyse TM-treated target cells while the two clones did not discriminate between the two targets. Accordingly, the three clones were termed anti-MHC oligosaccharide clones while the two clones were termed anti-MHC polypeptide clones. In inhibition of CML experiments using the dgl supernatant which contained Daudi PM oligosaccharide or using a anti-MHC class II monoclonal antibody; CML reactivity of the anti-MHC oligosaccharide clones was blocked by the dgl supernatant but not by the anti-MHC MoAb. On the other hand the anti-MHC polypeptide clones were only inhibited by the anti-MHC MoAb whether against intact or TM-treated targets. These studies strongly indicate that glycoconjugates of
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Bonnefoy-Berard, Nathalie. "Induction et régulation de l'activation des lymphocytes T et B par les globulines antilymphocytaires." Lyon 1, 1992. http://www.theses.fr/1992LYO1H086.

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Greenwood, M. R. "B lymphocyte differentiation." Thesis, Imperial College London, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375109.

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Jefferies, W. A. "Lymphocyte surface glycoproteins." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355757.

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McCrea, Anthony Philip. "The role of the T lymphocyte in B cell chronic lymphocytic leukaemia." Thesis, Queen's University Belfast, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335939.

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Moris, Arnaud. "On T lymphocyte alloreactivity." [S.l. : s.n.], 2000. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB8849701.

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Bonnefoix, Thierry. "Les lymphocytes T intra-tumoraux dans les lymphomes malins non hodgkiniens B : activation, prolifération et production de facteurs de régulation des cellules B." Grenoble 1, 1991. http://www.theses.fr/1991GRE10153.

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Les lymphocytes t sont constamment presents dans les ganglions envahis par un lymphome malin non hodgkinien b. Ce travail a permis de reunir des arguments en faveur de l'implication de ces cellules t dans le processus tumoral: diminution de la capacite des cellules t a produire de l'interleukine 2 (il2) et a proliferer en presence de pha; pourcentages eleves de cellules t dr+ (activees), et cd4+cd45ra-(memoires), ainsi que de cellules t cd25+ (p55 du recepteur de l'il2); a partir des cellules t cd25+ totales, il a ete obtenu des clones t capables de proliferer au contact des cellules b malignes autologues, mais pas au contact des cellules b normales (b-ebv) autologues; la nature des relations fonctionnelles entre les cellules t intra-tumorales et les cellules b malignes autologues reste a determiner: en utilisant des cellules b normales comme cibles des cellules t, il n'a pu etre mis en evidence aucune anomalie de production d'activites bcgf et bcdf mu et gamma
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Lumbroso, Serge. "Production spontanée in vitro par les lymphocytes circulants d'anticorps spécifiques de Brucella." Montpellier 1, 1990. http://www.theses.fr/1990MON11228.

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Barré, Vincent. "La leucemie a grands lymphocytes granuleux : a propos d'un cas ; revue de la litterature." Nice, 1992. http://www.theses.fr/1992NICE6541.

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Books on the topic "Lymphocyte"

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Pillai, Shiv. Lymphocyte Development. Boston, MA: Birkhäuser Boston, 1996. http://dx.doi.org/10.1007/978-1-4612-2444-0.

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International, Conference on Lymphocyte Activation and Immune Regulation (9th 2002 Newport Beach Calif ). Lymphocyte activation and immune regulation IX: Homeostasis and lymphocyte traffic. New York: Kluwer Academic/Plenum Publishers, 2002.

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Tsoukas, Constantine, ed. Lymphocyte Signal Transduction. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/0-387-34132-3.

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1948-, Cambier John C., ed. B-lymphocyte differentiation. Boca Raton, Fla: CRC Press, 1986.

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D, Shimizu Yoji Ph, ed. Lymphocyte adhesion molecules. Austin: R.G. Landes Co., 1993.

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International Conference on Lymphocyte Activation and Immune Regulation (3rd 1990 Newport Beach, Calif.). Mechanisms of lymphocyte activation and immune regulation III: Developmental biology of lymphocytes. New York: Plenum Press, 1991.

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International Conference on Lymphocyte Activation and Immune Regulation (9th 2002 Newport Beach, Calif.). Lymphocyte activation and immune regulation IX: Homeostasis and lymphocyte traffic. New York: Kluwer Academic/Plenum Publishers, 2002.

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International Conference on Lymphocyte Activation and Immune Regulation (9th 2002 Newport Beach, Calif.). Lymphocyte activation and immune regulation IX: Homeostasis and lymphocyte traffic. New York: Kluwer Academic/Plenum Publishers, 2002.

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Leong, Anthony S.-Y. 1945-, ed. Essential oncology of the lymphocyte. London: Springer-Verlag, 1987.

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Wilson, Dermot Clarence. Lymphocyte populations in pregnancy. [s.l: The Author], 1988.

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Book chapters on the topic "Lymphocyte"

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Pavelka, Margit, and Jürgen Roth. "Lymphocyte." In Functional Ultrastructure, 350–51. Vienna: Springer Vienna, 2010. http://dx.doi.org/10.1007/978-3-211-99390-3_179.

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Gooch, Jan W. "Lymphocyte." In Encyclopedic Dictionary of Polymers, 905. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_14153.

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Pillai, Shiv. "Overview of Cell Fate Decisions During Lymphoid Ontogeny." In Lymphocyte Development, 1–10. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_1.

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Pillai, Shiv. "The Activation and Differentiation of Mature T Lymphocytes." In Lymphocyte Development, 434–64. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_10.

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Pillai, Shiv. "The Development of Natural Killer Cells." In Lymphocyte Development, 465–82. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_11.

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Pillai, Shiv. "Naturally Occurring Disorders of Lymphocyte Development." In Lymphocyte Development, 483–505. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_12.

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Pillai, Shiv. "Commitment to a Lymphoid Fate." In Lymphocyte Development, 11–49. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_2.

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Pillai, Shiv. "V(D)J Recombination and the Generation of Diversity." In Lymphocyte Development, 50–73. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_3.

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Pillai, Shiv. "Pathways Mediating Signal Transduction and Cell Cycle Progression in Lymphocytes." In Lymphocyte Development, 74–200. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_4.

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Pillai, Shiv. "Molecular Mechanisms of Lymphocyte Apoptosis." In Lymphocyte Development, 201–36. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-2444-0_5.

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Conference papers on the topic "Lymphocyte"

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Garcia, Salomé, Bruno Miguel Fernandes, Sara Ganhão, Raquel Ferreira, Miguel Bernardes, Georgina Terroso, and Lúcia Costa. "AB1314 ROLE OF NEUTROPHIL TO LYMPHOCYTE RATIO, MONOCYTE TO LYMPHOCYTE RATIO, PLATELET TO LYMPHOCYTE RATIO, EOSINOPHIL TO LYMPHOCYTE AND BASOPHILE TO LYMPHOCYTE RATIO IN ASSESSING DISEASE ACTIVITY IN SPONDYLOARTHRITIS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.2243.

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Ferousis, Loukas, Vasilios Pergialiotis, Vasilios Lygizos, Ioannis Rodolakis, Eleftherios Zachariou, Dimitrios Efthymios Vlachos, Nikolaos Thomakos, and Dimitrios Haidopoulos. "723 Post-splenectomy neutrophil, lymphocytes, neutrophil to lymphocyte ratios and platelet to lymphocyte ratios and survival outcomes of advanced ovarian cancer patients." In ESGO 2024 Congress Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/ijgc-2024-esgo.701.

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Yang, Jinfeng, Yi Guan, and Xishuang Dong. "Lymphocyte-style word representations." In 2014 IEEE International Conference on Information and Automation (ICIA). IEEE, 2014. http://dx.doi.org/10.1109/icinfa.2014.6932783.

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Filippi, J. F., D. Arnoux, N. Tubiana, B. Boutière, F. Le Caär, J. Sampol, Lab Hématol, Pr J. Sampol, and Pr Y. Carcassonne. "PLASMINOGEN ACTIVATOR ACTIVITY OF NORMAL AND MALIGNANT MONONUCLEAR HUMAN CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643167.

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Plasminogen activators (PA) are thought to play a role in the invasive and metastatic properties of many types of cancer cells. Though, discrepancies in correlations between fibrinolytic activity and metastatic potential of malignant cells have been described.In this study, we evaluated both tissue type (tPA) and urokinase type (UK) cellular PA activities in different mononuclear cell types : normal T and B human peripheral lymphocytes, B cells from patients with chronic lymphocytic leukemia (CLL), human blood monocytes, alveolar macrophages, U 937, RAJI and JM cell 1ines.Mononuclear cells were isolated by Ficoll-hypaque gradients and monocytes by plastic adhesion. T and B cells were separated by a rosetting technique using sheep red blood cells. Cellular extracts were prepared by 0.5 % Triton X 100 buffer treatment followed by sonication and centrifugation 10 ' at 2000 g. PA assays were performed on the supernatants.UK-type PA was evaluated by a liquid-phase assay in presence of human plasminogen (Kabi) and chromogenic substrate S 2251 (Kabi).tPA was determinated using a solid-phase fibrin activity assay which involves an affinity separation step and thus allows selective detection of tPA.In both cases, results were reported in international units by reference to standard curves of UK (Choay) or tPA (Kabi).In all cell types tested, PA detected was essentially urokinase-type. Highest PA activity was found in U 937 cells (0.7 IU/5×l06 cells). In normal blood lymphocytes, mean PA activity was 0.08 IU/5×l06 cells. Examination of lymphocytes from patients with CLL revealed a marked decrease in UK activity as compared to normals (< 0.01 IU/5×106 cells in more than 50 % cases).The function of PA in normal lymphocyte physiology and the potential pathogenic role of diminished PA in CLL lymphocytes remains to be investigated.
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Cherneva, Radostina, and Zheyna Cherneva. "Neutrophil-to-lymphocyte, platlet-to-lymphocyte ratio and adiposityin early COVID -19." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa3883.

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Burmester, G., W. F. C. Rigby, E. Choy, P. Nash, K. Winthrop, P. J. Mease, P. Young, et al. "SAT0330 Changes in lymphocytes and lymphocyte subsets in tofacitinib-treated patients with psoriatic arthritis." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.3490.

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Babaoğlu, Elif, Sevinc Sarinc Ulasli, Emine Keles, Elif Tugce Korkmaz, Deniz Koksal, and Salih Emri. "Importance of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in COPD exacerbations." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2097.

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Sanchez-Salcedo, Pablo, Jessica Gonzalez, Diego Martinez-Urbistondo, Juan Berto, Pilar Rivera, Esmeralda Lopez-Zalduendo, Ana Belen Alcaide, Arantzazu Campo, Juan Pablo De Torres, and Javier Zulueta. "Exploring the neutrophil/lymphocyte and platelet/lymphocyte ratios as biomarkers for lung cancer development." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa4241.

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Huszno, Joanna, Zofia Kolosza, Jolanta Mrochem Kwarciak, and Aleksander Zajusz. "Abstract P3-08-67: Prognostic value of the neutrophil-lymphocyte, platelet-lymphocyte and monocyte-lymphocyte ratio breast cancer patients according to HER2 overexpression." In Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-p3-08-67.

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Kim, Sang Il. "EP124/#117 Preoperative neutrophil-to-lymphocyte, platelet-to-lymphocyte and monocyte-to-lymphocyte ratio as a prognostic factor in non-endometrioid endometrial cancer." In IGCS 2022 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-igcs.215.

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Reports on the topic "Lymphocyte"

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นิลอุบล, เดชฤทธิ์, อังคณา ตันติธุวานนท์, ธิติมา ไตรพิพัฒน์, and อรรถพล มาดาป้อง. การทดสอบประสิทธิภาพของดีเอ็นเอวัคซีนในภาคสนามเพื่อควบคุมโรคพีอาร์อาร์เอส : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2014. https://doi.org/10.58837/chula.res.2014.67.

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การดำเนินงานวิจัยนี้มีวัตถุประสงค์เพื่อผลิตต้นแบบดีเอ็นเอวัคซีนเพื่อป้องกันโรคติดเชื้อไวรัสพีอาร์อาร์เอส โดยดีเอ็นเอต้นแบบที่ผลิตขึ้นมีส่วนประกอบของยีน ORF5 ของไวรัสพีอาร์อาร์เอสที่มีการแทรกยีน PADRE ระหว่าง decoy epitope และ neutralizing epitope และศึกษาประสิทธิภาพของดีเอ็นเอวัคซีนต้นแบบนั้นในการกระตุ้นสร้าง neutralizing antibody แบ่งการวิจัยออกเป็น 3 ส่วนประกอบด้วย การผลิตดีเอ็นเอวัคซีน การทดสอบขนาดที่ใช้และการทดสอบประสิทธิภาพการกระตุ้นภูมิคุ้มทั้งโดยวัดจาก serum neutralization และ lymphocyte proliferative assays ในภาคสนาม ผลการทดลองพบว่าดีเอ็นเอวัคซีนที่พัฒนาขึ้นสามารถกระตุ้นสร้างแอนติบอดีและกระตุ้นให้เกิดการตอบสนองของเซลล์ลิมโฟไซต์เมื่อวัดโดยวิธี serum neutralization และ lymphocyte proliferative assays แต่ผลการตอบสนองช้าและไม่สูง ดังนั้นจึงอาจต้องดำเนินการวิจัยต่อเพื่อพัฒนาดีเอ็นเอวัคซีนให้มีประสิทธิภาพที่ดียิ่งขึ้น
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Splitter, Gary, Zeev Trainin, and Yacov Brenner. Lymphocyte Response to Genetically Engineered Bovine Leukemia Virus Proteins in Persistently Lymphocytic Cattle from Israel and the U.S. United States Department of Agriculture, July 1995. http://dx.doi.org/10.32747/1995.7570556.bard.

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The goal of this proposal was to identify proteins of BLV recognized by lymphocyte subpopulations and determine the contribution of these proteins to viral pathogenesis. Our hypothesis was that BLV pathogenesis is governed by the T-cell response and that the immune system likely plays an important role in controlling the utcome of infection. Our studies presented in ths final report demonstrate that T cell competency declines with advancing stages of infection. Dramatic differences were observed in lymphocyte proliferation to recombinant proteins encoded by BLV gag (p12, p15, and p24) and env (gp30 and gp15) genes in different disease stages. Because retroviruses are known to mutate frequently, examinatin of infected cattle from both Israel and the United States will likely detect variability in the immune response. This combined research approach provides the first opportunity to selectively address the importance of T-cell proliferation to BLV proteins and cytokines produced during different stages of BLV infection. Lack of this information regarding BLV infection has hindered understanding lympocyte regulation of BLV pathogenesis. We have developed the essential reagents necessary to determine the prominence of different lymphocyte subpopulations and cytokines produced during the different disease stages within the natural host. We found that type 1 cytokines (IL-2 and IFN-g) increased in PBMCs from animals in early disease, and decreasd in PBMCs from animals in late disease stages of BLV infection, while IL-10, increased with disease progression. Recently, a dichotomy between IL-12 and IL-10 has emerged in regards to progression of a variety of diseases. IL-12 activates type 1 cytokine production and has an antagonistic effect on type 2 cytokines. Here, using quantitative competitive PCR, we show that peripheral blood mononuclear cells from bovine leukemia virus infected animals in the alymphocytotic disease stage express increased amount of IL-12 p40 mRNA. In contrast, IL-12 p40 mRNA expression by PL animals was significantly decreased compared to normal and alymphocytotic animals. To examine the functions of these cytokines on BLV expression, BLV tax and pol mRNA expression and p24 protein production were quantified by competitive PCR, and by immunoblotting, respectively. IL-10 inhibited BLV tax and pol mRNA expression by BLV-infected PBMCs. In addition, we determined that macrophages secret soluble factor(s) that activate BLV expression, and that secretion of the soluble factor(s) could be inhibited by IL-10. In contrast, IL-2 increased BLV tax and pol mRNA, and p24 protein production. These findings suggest that macrophages have a key role in regulating BLV expression, and IL-10 produced by BLV-infected animals in late disease stages may serve to control BLV expression, while IL-2 in the early stage of disease may activate BLV expression. PGE2 is an important immune regulator produced only by macrophages, and is known to facilitate HIV replication. We hypothesized that PGE2 may regulate BLV expression. Here, we show that cyclooxygenase-2 (COX-2) mRNA expression was decreased in PBMCs treated with IL-10, while IL-2 enhanced COX-2 mRNA expression. In contrast, addition of PGE2 stimulated BLV tax and pol mRNA expression. In addition, the specific COX-2 inhibitor, NS-398, inhibited BLV expression, while addition of PGE2 increased BLV tax expression regardless of NS-398. These findings suggest that macrophage derived cyclooxygenase -2 products, such as PGE2, may regulate virus expression and disease rogression in BLV infection, and that cytokines (IL-2 and IL-10) may regulate BLV expression through PGE2 production.
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Rabinowich, Hannah. Protective Mechanisms Against Lymphocyte Apoptosis Induced by Breast Carcinoma. Fort Belvoir, VA: Defense Technical Information Center, October 2002. http://dx.doi.org/10.21236/ada411729.

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Peng, Liang, Baodi Cao, Fangpeng Hou, Baolin Xu, Baolin Xu, Luyi Liang, Yu Jiang, Xiaohui Wang, and Jingjian Zhou. Relationship between platelet to lymphocyte ratio (PLR) and lymphocyte to monocyte ratio (LMR) with spontaneous preterm birth: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2022. http://dx.doi.org/10.37766/inplasy2022.3.0092.

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Tsoukas, Constantine D. Effects of Immunomodulatory Drugs on T Lymphocyte Activation and Function. Fort Belvoir, VA: Defense Technical Information Center, November 1989. http://dx.doi.org/10.21236/ada225770.

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Liang, BiYan, BiYan Liang, and Jian Wang. A Meta Analysis of the Efficacy of Tonic Method in Traditional Chinese Medicine for AIDS Immunological Nonresponses. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0077.

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Review question / Objective: To evaluate the efficacy of tonic method in treating AIDS immunological nonresponses. Eligibility criteria: ①Study type: RCT based on tonic method in TCM for AIDS INRs. The language was limited to Chinese and English. ②The research object: HIV/AIDS patients with any disease stage; the intervention objects were adults with no gender restrictions. ③Intervention measures: The treatment group was treated with tonic prescriptions combined with ART, including four types of prescriptions for nourishing qi, nourishing blood, nourishing yin, or nourishing yang; the dosage, frequency, and method were not limited. The control group was treated with ART or mock agent and placebo. ④Outcome indicators: The observation indicators reported in the included studies should include at least one of the following indicators: 1) Effective rate of immune function reconstruction: formulated in accordance with "AIDS (Adult) Chinese Medicine Diagnosis and Treatment Program" (2016 Edition) , effective: CD4 + T lymphocyte counts increased by ≥ 50 cells/l or ≥ 30%, invalid: CD4+ T lymphocyte counts decreased by ≥ 50 cells/l or ≥ 30%; total effective rate = effective number/total number; 2) CD4+T lymphocyte counts level.
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กาญจนะพังคะ, สุมลยา. การศึกษาเม็ดเลือดขาวและเกล็ดเลือดในกระแสโลหิตของปลาดุก ด้วยกล้องจุลทัศน์แสงสว่างและกล้องจุลทัศน์อิเลคตรอนแบบลำแสงผ่าน. จุฬาลงกรณ์มหาวิทยาลัย, 1998. https://doi.org/10.58837/chula.res.1998.53.

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ศึกษารายละเอียดโครงสร้างเม็ดเลือดขาวและเกล็ดเลือดในกระแสโลหิตของปลาดุก (Clariasbatrachus) ด้วยกล้องจุลทัศน์แสงสว่าง และกล้องจุลทัศน์อิเลคตรอนแบบลำแสงผ่าน พบเกล็ดเลือดลักษณะโครงสร้างต่างกัน 3 ชนิด พบเม็ดเลือดขาวชนิด lymphocyte monocyte และ neutrophil neutrophil เป็น granular leucocyte เพียงชนิดเดียวที่พบ มีทั้งชนิดที่เจริญเต็มที่และยังไม่เจริญเต็มที่ monocyte เกือบทุกเซลล์มีโครงสร้างที่มีลักษณะเฉพาะคือ microfilamentous structure อยู่ชิดรอยหยักของนิวเคลียสในเซลล์ การศึกษาครั้งนี้ได้บรรยายถึงการเปลี่ยนแปลงโครงสร้างของเกล็ดเลือดและ granulocyte ในกระบวนการแข็งตัวของเลือดปลาดุกได้ง่าย
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Cohen, Lorenzo. The Effects of Cocaine and Stress on Lymphocyte Proliferation in Rats. Fort Belvoir, VA: Defense Technical Information Center, January 1993. http://dx.doi.org/10.21236/ad1011161.

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Avihingsanon, Yingyos, Jongkonnee Wongpiyabovorn, and Nattiya Hirankarn. Biomarker discovery in systemic lupus erythematosus: genome-methylation approaches : Research report. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.15.

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Discovery of novel biomarkers in lupus nephritis Biomarkers are needed for making diagnosis and prognosis. In lupus nephritis, conventional tests like urinalysis or serum creatinine remain inadequate for patient care. In this proposal, we focused on non-invasive tools like blood and urine mRNAs or proteins. We chose candidate genes involving regulatory T-cell, B-lymphocyte signatures or vascular protective factors. Expression of regulatory cell signature (FOXP3) in peripheral blood mononuclear cells is associated with activity of lupus nephritis. We found FOXP3 mRNA levels in PBMCs from patients with active lupus nephritis were significantly lower than inactive lupus nephritis. Expression levels of FOXP3 mRNA were associated with pathological activity index, cellular crescent and fibrinoid necrosis. BLyS and APRIL are B-lymphocyte related cytokines that play an important role in generating and maintaining the mature B-cell pool. In this study, we found blood APRIL correlated with activity of lupus nephritis. Blood APRIL levels could precisely predict failure of standard treatment treatment. APRIL is a potential biomarker for predicting treatment failure. Lastly, we found an expression of VEGF in renal tissue may serve as a molecular marker of renal damage from LN and may be a predictive factor for short-term loss of kidney function in lupus nephritis patients. We proposed that reduction of intra-renal VEGF level caused by losses of podocyte cells. Genetic polymorphism of drug toxicity or pharmacokinetics in SLE patients We began to explore the pharmacokinetics and pharmacogenomics of two important immunosuppressants, azathioprine and mycophenolate. In this study, we report TPMT polymorphisms and TPMT enzyme activity were important predictors of AZA-induced myelosuppression. The tests are available for routine care. Mycophenolic acid (MPA) is active metabolite of mycophenalate. We found MPA levels is important predictor of therapeutic response. The therapeutic drug monitoring is now an important issue of patient care. We found UGT1A9 polymorphism may play a pivotal role in drug metabolisms. Methylation study We examined and compared the methylation levels of long terminal repeats (LTRs) and non-LTR retroelements in normal and SLE CD4+ T lymphocytes, CD8+ T lymphocytes and B lymphocytes. Hypomethylation of LINE-1 but not Alu was found in CD4+ T lymphocytes, CD8+ T lymphocytes, and B lymphocytes of SLE patient. Moreover, when the SLE patients were divided into active and inactive groups, LINE-1 hypomethylation was more significantly distinguished in both CD4+ and CD8+ T lymphocytes of patients from the active SLE group when compared to the controls. Genome-wide scanning using SNP microarrays In this study, we applied case-control association study including pooling genome wide association (GWA) and candidate gene association studies to search for SNPs associated with SLE susceptibility and/or severity. We could not identify any SNPs with distinct p-value or odds ratio from our pooling GWA result due to limited power. We selected IFIX for further study in candidate gene’s part. Besides IFIX, we also focus on MNDA, IFI16 and AIM2 genes which located in the same region and are all IFN-inducible genes. They are important SLE susceptibility genes due to several reasons including 1) genetic mapping from lupus murine model and 2) an upregulated IFN-inducible genes in patients with SLE from microarray studies and 3) IFI16 was identified as new autoantigen for patients with SLE. We genotyped 10 SNPs from these 4 genes and found that SNP within IFIX and IFI16 are independently important.
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กิตนะ, จิรารัช, นพดล กิตนะ, วิเชฏฐ์ คนซื่อ, ผุสตี ปริยานนท์, มุกเรขา เชี่ยวชาญชัย, ยุพาพร วิสูตร, ธฤษวรรณ ไตรจิตร์, et al. สุขภาวะ และชีววิทยาการสืบพันธุ์ของกบทูดในพื้นที่ปกปักพันธุกรรมพืชอันเนื่องมาจากพระราชดำริฯ : รายงานผลการดำเนินงาน. จุฬาลงกรณ์มหาวิทยาลัย, 2019. https://doi.org/10.58837/chula.res.2019.22.

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พื้นที่โครงการอนุรักษ์พันธุกรรมพืชอันเนื่องมาจากพระราชดำริฯ ประกอบด้วยระบบนิเวศหลากหลาย ที่ยังคงสภาพอุดมสมบูรณ์ จากผลการศึกษาในภาคสนามที่ผ่านมาพบว่าในพื้นที่ศูนย์ศึกษาการพัฒนาห้วยฮ่องไคร้อันเนื่องมาจากพระราชดำริ จ.เชียงใหม่ มีความหลากหลายทางชีวภาพของสัตว์สะเทินน้ำสะเทินบกค่อนข้างสูง มีสัตว์สะเทินน้ำสะเทินบกชนิดสำคัญ เช่น กบทูด Limnonectes blythii ซึ่งเป็นสัตว์สะเทินน้ำสะเทินบกที่มีขนาดใหญ่ที่สุดในประเทศไทยและมีสถานภาพเป็นสัตว์ป่าคุ้มครอง และจากศักยภาพในการพัฒนาเป็นสัตว์เศรษฐกิจ โดยคณะผู้วิจัยได้สำรวจสุขภาวะจากค่าทางโลหิตวิทยาของกบทูดในพื้นที่ศูนย์ศึกษาการพัฒนาห้วยฮ่องไคร้อันเนื่องมาจากพระราชดำริ ในเดือนมกราคม พ.ศ. 2560 และกุมภาพันธ์ พ.ศ. 2561 (ฤดูแล้งหนาว) เดือนเมษายน พ.ศ. 2560 (ฤดูแล้งร้อน) และเดือนสิงหาคม พ.ศ. 2560 (ฤดูฝน) ได้กบทูดจำนวนทั้งหมด 23 ตัว เป็นกบเพศผู้ 13 ตัว มีน้ำหนักเฉลี่ย 295 กรัม มีความยาวจากปลายจมูกถึงรูทวารเฉลี่ย 141 มิลลิเมตร ได้กบทูดเพศเมียทั้งหมด 5 ตัว มีน้ำหนักเฉลี่ย 216 กรัม มีความยาวจากปลายจมูกถึงรูทวารเฉลี่ย 131 มิลลิเมตร และได้กบระยะ juvenile 5 ตัว จากการศึกษาทางโลหิตวิทยา พบว่ากบทูดมีเซลล์เม็ดเลือดประกอบด้วย erythrocyte, thrombocyte และ leukocyte 5 ชนิด ได้แก่ monocyte, lymphocyte, neutrophil, eosinophil และ basophil โดยที่มีลักษณะทางสัณฐานคล้ายคลึงกับกบชนิดอื่น ๆ ที่เคยมีรายงาน นอกจากนี้ยังพบว่ากบทูดมีการติดปรสิตในเลือด 3 กลุ่ม ได้แก่ Hepatozoon sp. มีกบทูดติดปรสิตชนิดนี้รวม 15 ตัว Microfilaria worm มีกบทูดติดปรสิตชนิดนี้รวม 3 ตัว และ Trypanosoma sp. มีกบทูดติดปรสิตชนิดนี้เพียง 1 ตัว คิดเป็นค่าความชุก (Prevalence) โดยรวมเท่ากับ 65% จากการศึกษาสัดส่วนของเซลล์เม็ดเลือดขาวแต่ละชนิด พบว่า เซลล์เม็ดเลือดขาวชนิด lymphocyte เป็นชนิดที่พบมากที่สุด และการติดปรสิตในเลือดมีผลต่อค่าสัดส่วนเซลล์เม็ดเลือดขาวบางชนิดเท่านั้น ได้แก่ ค่าสัดส่วนของ eosinophil มีค่ามากกว่าในกบทูดที่ติดปรสิต และ monocyte มีค่าต่ำกว่าในกบทูดที่ติดปรสิต ข้อมูลที่ได้จะเป็นประโยชน์ในการศึกษาสุขภาวะและชีววิทยาการสืบพันธุ์ของกบทูดในพื้นที่โครงการ อพ.สธ. ต่อไป เพื่อให้เข้าใจพลวัตประชากรและนิเวศสรีรวิทยาของกบทูด เพื่อการวางแผนการอนุรักษ์และใช้ประโยชน์ในระยะยาวต่อไป
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You might also be interested in the extended bibliographies on the topic 'Lymphocyte' for particular source types:
Journal articles Dissertations / Theses Books
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