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Journal articles on the topic "Lymne (Eng.)"
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Sanderson, Victoria P., Jennifer C. Miller, Vladimir V. Bamm, Manali Tilak, Vett K. Lloyd, Gurpreet Singh-Ranger, and Melanie K. B. Wills. "Profiling disease burden and Borrelia seroprevalence in Canadians with complex and chronic illness." PLOS ONE 18, no. 11 (November 8, 2023): e0291382. http://dx.doi.org/10.1371/journal.pone.0291382.
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Lyme disease, caused by vector-borne Borrelia bacteria, can present with diverse multi-system symptoms that resemble other conditions. The objective of this study was to evaluate disease presentations and Borrelia seroreactivity in individuals experiencing a spectrum of chronic and complex illnesses. We recruited 157 participants from Eastern Canada who reported one or more diagnoses of Lyme disease, neurological, rheumatic, autoimmune, inflammatory, gastrointestinal, or cardiovascular illnesses, or were asymptomatic and presumed healthy. Intake categories were used to classify participants based on their perceived proximity to Lyme disease, distinguishing between those with a disclosed history of Borrelia infection, those with lookalike conditions (e.g. fibromyalgia syndrome), and those with unrelated ailments (e.g. intestinal polyps). Participants completed three questionnaires, the SF-36 v1, SIQR, and HMQ, to capture symptoms and functional burden, and provided blood serum for analysis at an accredited diagnostic lab. Two-tiered IgG and IgM serological assessments (whole cell ELISA and Western blot) were performed in a blinded fashion on all samples. The pattern of symptoms and functional burden were similarly profound in the presumptive Lyme and Lyme-like disease categories. Borrelia seroprevalence across the study cohort was 10% for each of IgG and IgM, and occurred within and beyond the Lyme disease intake category. Western blot positivity in the absence of reactive ELISA was also substantial. Fibromyalgia was the most common individual diagnostic tag disclosed by two-tier IgG-positive participants who did not report a history of Lyme disease. Within the IgG seropositive cohort, the presence of antibodies against the 31 kDa Outer Surface Protein A (OspA) was associated with significantly better health outcomes. Previously, this marker has been linked to treatment-refractory Lyme arthritis. Overall, our findings support prior observations of phenotypic overlap between Lyme and other diseases. Seropositivity associated with non-specific symptoms and functional impairment warrants further mechanistic investigation and therapeutic optimization.
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Coiffier, Guillaume, and Pierre Tattevin. "Lyme disease: “End of the debate?”." Joint Bone Spine 88, no. 4 (July 2021): 105181. http://dx.doi.org/10.1016/j.jbspin.2021.105181.
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Yarema, Nadiya, Kateryna Myndziv, and Volodymyr Dzhyvak. "Lyme carditis in clinical practice." Acta Facultatis Medicae Naissensis 41, no. 1 (2024): 139–45. http://dx.doi.org/10.5937/afmnai41-39831.
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Introduction. Lyme disease is an infectious disease transmitted by the Ixodes ticks and is manifested by damaging various organs and systems (most often-migrating erythema, damage to the nervous system, musculoskeletal system, heart, liver and eyes). According to various authors, heart damage in Lyme borreliosis ranges from 4% to 10% and is an understudied pathology. Case report. The article describes a clinical case of infectious myocarditis associated with Lyme disease in a 51-year-old patient. The course of the disease and the results of treatment of the patient were analyzed. The severe rhythm and conduction disorders were revealed: antrioventricular (AV) block of the first degree, transient AV block of the II degree (Mobitz 2) and III degree, polytopic extrasystoles. Due to timely diagnosis, including serological, prescribed etiotropic antibacterial treatment, the patient achieved a significant improvement in both clinical condition and positive serological and electrocardiogram (ECG) dynamics with improved AV conduction. Conclusions. The most frequent ECG changes in Lyme carditis (LC) are conduction disorders with the development of blockades of various stages. For patients with myocarditis, which is accompanied by complex arrhythmias, and conduction disorders estimated as intermediate and high risk by Suspicious Index in Lyme Carditis (SILC) scale, serological examination should be recommended in order to verify the borreliosis etiology of myocarditis. In this particular case, early diagnostics and prescribed etiotropic treatment, in addition to treatment of heart failure, contributed to a significant improvement in both the clinical condition and positive serological and ECG dynamics.
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Kennel, Peter J., Melvin Parasram, Daniel Lu, Diane Zisa, Samuel Chung, Samuel Freedman, Katherine Knorr, Timothy Donahoe, Steven M. Markowitz, and Hadi Halazun. "A Case of Lyme Carditis Presenting with Atrial Fibrillation." Case Reports in Cardiology 2018 (September 2, 2018): 1–5. http://dx.doi.org/10.1155/2018/5265298.
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We report a case of a 20-year-old man who presented to our institution with a new arrhythmia on a routine EKG. Serial EKG tracings revealed various abnormal rhythms such as episodes of atrial fibrillation, profound first degree AV block, and type I second degree AV block. He was found to have positive serologies for Borrelia burgdorferi. After initiation of antibiotic therapy, the atrial arrhythmias and AV block resolved. Here, we present a case of Lyme carditis presenting with atrial fibrillation, a highly unusual presentation of Lyme carditis.
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Shabbir, Muhammad Asim, Muhammad Hamza Saad Shaukat, Muhammad Hashaam Arshad, and Joseph Sacco. "Lyme carditis presenting as atrial fibrillation in a healthy young male." BMJ Case Reports 12, no. 6 (June 2019): e229261. http://dx.doi.org/10.1136/bcr-2019-229261.
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We present a case of a 23-year-old man coming with palpitations, found to be in atrial fibrillation (AF). He was initially managed with metoprolol for rate-controlled therapy—reverted to normal sinus rhythm and discharged home. He returned a few days later—this time in varying degrees of atrioventricular block including transient complete heart block. He was empirically started on intravenous ceftriaxone for suspected Lyme carditis, which subsequently led to the resolution of high-degree heart block. Lyme immunoglobulin G (IgG) and IgM returned positive. Follow-up ECG after the course of antibiotic exhibited normal sinus rhythm. AF is a rare presentation of Lyme disease but still exists. It should be considered in terms of appropriate treatment, especially in Lyme-endemic areas.
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Muhammad, Sheheryar, and Robert J. Simonelli. "Lyme Carditis: A Case Report and Review of Management." Hospital Pharmacy 53, no. 4 (January 2, 2018): 263–65. http://dx.doi.org/10.1177/0018578717749927.
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Purpose: A case report of a patient who presented with an acute onset, fluctuating atrioventricular (AV) block and was diagnosed with Lyme carditis is presented. Summary: A 55-year-old man with progressively worsening generalized malaise, flu-like symptoms, dyspnea on exertion, and near syncope was admitted with bradycardia (heart rate was between 20 and 30 beats per minute upon admission). He endorsed having several tick bites after which he developed erythema migrans on his arm and abdomen. An electrocardiogram (ECG) revealed a second-degree AV block, fluctuating between Mobitz type I and Mobitz type II heart block, with a P-R interval of 300 ms. A presumptive diagnosis of Lyme carditis was made based on a confirmed history of tick exposure, presence of erythema migrans, and AV block. The patient was started on ceftriaxone. On day 3 of hospitalization, patient’s heart rate was between 50 and 60 beats per minute. A diagnosis of Lyme disease was confirmed based on serologic testing. A repeat ECG revealed a first-degree AV block with a P-R interval of 300 ms. On day 5 of hospitalization, a peripherally inserted central catheter line was placed and the patient was discharged to his home on a 28-day course of ceftriaxone. Patient’s heart rate was 65 beats per minute on discharge day. Conclusion: Considering Lyme carditis as a differential diagnosis in patients with an AV block of an unknown etiology can result in a timely diagnosis and treatment of Lyme carditis.
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Dersch, R., M. H. Freitag, S. Schmidt, H. Sommer, S. Rauer, and J. J. Meerpohl. "Efficacy and safety of pharmacological treatments for acute Lyme neuroborreliosis - a systematic review." European Journal of Neurology 22, no. 9 (June 8, 2015): 1249–59. http://dx.doi.org/10.1111/ene.12744.
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Marx, Grace E., Anna M. Schotthoefer, Brian S. Schwartz, Evan Draper, Christina G. Rivera, John Zeuli, Erica Scotty, et al. "1198. Lyme Disease Post-Exposure Prophylaxis by Single-Dose Doxycycline in Three Healthcare Systems." Open Forum Infectious Diseases 8, Supplement_1 (November 1, 2021): S690. http://dx.doi.org/10.1093/ofid/ofab466.1390.
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Abstract Background Lyme disease, the most common tickborne disease in the United States, may be prevented by taking a single 200-mg dose of oral doxycycline after a high-risk bite from a blacklegged tick. Currently, it is not known how Lyme disease post-exposure prophylaxis (PEP) might vary by region and healthcare system. We identified single-dose doxycycline medication orders in three healthcare systems in states with high incidence of Lyme disease and compared associated patient and provider characteristics. Methods Electronic health record data during 2012 – 2016 were obtained from three healthcare systems: Geisinger (Pennsylvania), Marshfield Clinic (Wisconsin), and Mayo Clinic (Minnesota/Wisconsin). Creation of analytic variables and analysis were harmonized across the three sites. Medication orders for single-dose doxycycline ≤200 mg that were accompanied by specific key words or diagnostic codes (e.g., tick bite; Lyme disease prevention) were considered evidence of PEP. Manual chart review was performed from a random subset to evaluate the algorithms used to identify PEP. Results Among 2,937,585 patients with at least one medication order or clinical encounter during the study period, 14,102 single-dose doxycycline orders for Lyme disease PEP for 13,172 unique patients were identified. The typical patient receiving PEP was older (mean age 51 – 58 years), male (56 – 59%), and non-Hispanic White (81 – 98%). The annual seasonality of medication orders was bimodal, with peaks occurring during April – July and October – November. The most common encounter setting was an outpatient clinic or urgent care center (80 – 91%); medication orders after patient phone calls in the absence of an in-person visit occurred frequently (14 – 19%) in two health systems. Chart abstractions (n=600) revealed instances of PEP prescribed inappropriately (e.g., bite from a non-blacklegged tick; patient with symptoms of acute Lyme disease). Conclusion Lyme disease PEP with a single dose of doxycycline was frequently prescribed in healthcare systems where there is a high incidence of Lyme disease. PEP was most commonly prescribed to non-Hispanic Whites over the age of 50 years. Public health initiatives for tickborne disease prevention should include clinician education on the appropriate use of Lyme disease PEP. Disclosures Anna M. Schotthoefer, PhD, HelixBind (Other Financial or Material Support, salary support) John Zeuli, PharmD, INSMED (Other Financial or Material Support, honoraria for educational speaking)
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Michalski, Basia, and Adrian Umpierrez De Reguero. "Lyme Carditis Buried Beneath ST-Segment Elevations." Case Reports in Cardiology 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/9157625.
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Lyme disease is caused by the spirochete Borrelia burgdorferi and is carried to human hosts by infected ticks. There are nearly 30,000 cases of Lyme disease reported to the CDC each year, with 3-4% of those cases reporting Lyme carditis. The most common manifestation of Lyme carditis is partial heart block following bacterial-induced inflammation of the conducting nodes. Here we report a 45-year-old gentleman that presented to the hospital with intense nonradiating chest pressure and tightness. Lab studies were remarkable for elevated troponins. EKG demonstrated normal sinus rhythm with mild ST elevations. Three weeks prior to hospital presentation, patient had gone hunting near Madison. One week prior to admission, he noticed an erythematous lesion on his right shoulder. Because of his constellation of history, arthralgias, and carditis, he was started on ceftriaxone to treat probable Lyme disease. This case illustrates the importance of thorough history taking and extensive physical examination when assessing a case of possible acute myocardial infarction. Because Lyme carditis is reversible, recognition of this syndrome in young patients, whether in the form of AV block, myocarditis, or acute myocardial ischemia, is critical to the initiation of appropriate antibiotics in order to prevent permanent heart block, or even death.
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Ozdenerol, Esra, Rebecca Michelle Bingham-Byrne, and Jacob Daniel Seboly. "The Effects of Lifestyle on the Risk of Lyme Disease in the United States: Evaluation of Market Segmentation Systems in Prevention and Control Strategies." International Journal of Environmental Research and Public Health 18, no. 24 (December 7, 2021): 12883. http://dx.doi.org/10.3390/ijerph182412883.
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The aim of this study was to investigate lifestyles at risk of Lyme disease, and to geographically identify target populations/households at risk based on their lifestyle preferences. When coupled with geographically identified patient health information (e.g., incidence, diagnostics), lifestyle data provide a more solid base of information for directing public health objectives in minimizing the risk of Lyme disease and targeting populations with Lyme-disease-associated lifestyles. We used an ESRI Tapestry segmentation system that classifies U.S. neighborhoods into 67 unique segments based on their demographic and socioeconomic characteristics. These 67 segments are grouped within 14 larger “LifeModes” that have commonalities based on lifestyle and life stage. Our dataset contains variables denoting the dominant Tapestry segments within each U.S. county, along with annual Lyme disease incidence rates from 2000 through 2017, and the average incidence over these 18 years. K-means clustering was used to cluster counties based on yearly incidence rates for the years 2000–2017. We used analysis of variance (ANOVA) statistical testing to determine the association between Lyme disease incidence and LifeModes. We further determined that the LifeModes Affluent Estates, Upscale Avenues, GenXurban, and Cozy Country Living were associated with higher Lyme disease risk based on the results of analysis of means (ANOM) and Tukey’s post hoc test, indicating that one of these LifeModes is the LifeMode with the greatest Lyme disease incidence rate. We further conducted trait analysis of the high-risk LifeModes to see which traits were related to higher Lyme disease incidence. Due to the extreme regional nature of Lyme disease incidence, we carried out our national-level analysis at the regional level. Significant differences were detected in incidence rates and LifeModes in individual regions. We mapped Lyme disease incidence with associated LifeModes in the Northeast, Southeast, Midcontinent, Rocky Mountain, and Southwest regions to reflect the location-dependent nature of the relationship between lifestyle and Lyme disease.
Books on the topic "Lymne (Eng.)"
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Dead men tapping: The end of the Heather Lynne II. Camden, Me: International Marine/McGraw-Hill, 2004.
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Hall, Verne M., and Elizebeth B. Plimpton. Vital Records of Lyme, Connecticut to the End of the Year 1850. Heritage Books Inc, 1990.
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Newton, Lady. The House of Lyme From its Foundation to the end of the Eighteenth Century. Franklin Classics, 2018.
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Newton, Evelyn Caroline Legh. The House of Lyme From its Foundation to the end of the Eighteenth Century. Franklin Classics, 2018.
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Yeomans, Kate. Dead Men Tapping : The End of the Heather Lynn II. International Marine/Ragged Mountain Press, 2003.
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Yeomans, Kate. Dead Men Tapping : The End of the Heather Lynn II. International Marine/Ragged Mountain Press, 2003.
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Glass, Richard M. Eponyms. Oxford University Press, 2009. http://dx.doi.org/10.1093/jama/9780195176339.003.0016.
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Eponyms are names or phrases derived from or including the name of a person or place. These terms are used in a descriptive or adjectival sense1 in medical and scientific writing to describe entities such as diseases, syndromes, signs, tests, methods, and procedures. These eponymous terms should be distinguished from true possessives (eg, Homer’s Iliad). Medical eponyms are numerous (a website devoted to medical eponyms lists more than 7000), are frequently used in medical publications, and are treated in dictionaries of eponyms covering general medicine3 and some specialties, eg, neurology. Eponyms historically have indicated the name of the describer or presumptive discoverer of the disease (eg, Alzheimer disease) or sign (eg, Murphy sign), the name of a person or kindred found to have the disease described (eg, Christmas disease), or, when based on the name of a place (technically, toponyms), the geographic location in which the disease was found to occur (eg, Lyme disease)...
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Artt, Sarah. Quiet Pictures. Bloomsbury Publishing Inc, 2024. http://dx.doi.org/10.5040/9781501347245.
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Quiet Pictures approaches the films of Joanna Hogg, Lynne Ramsay, Céline Sciamma, and Lucile Hadžhalilovicthrough the lens of silence as a motif and texture. This book takes up the question of different uses of silence in the work of these directors and how this creates a space for foregrounding innovative practices that establish new ways of looking, staring, and gazing. Sarah Artt discusses how the deliberate deployment of silence creates space for the formation of reciprocal gazes that counteract the typically gendered and binary ways in which women and femme-presenting people tend to be portrayed on screen. Quiet Pictures draws on the political legacy of feminist film theory to explore and conceptualise what it means to not just look back, but to share the gaze. This book discusses several films, including: Unrelated (Hogg, 2007), Archipelago (Hogg, 2010), Exhibition (Hogg, 2013), The Souvenir Part I and II (Hogg, 2019 and 2021), Morvern Callar (Ramsay, 2002), We Need to Talk About Kevin (Ramsay, 2011), Innocence (Hadžhalilovic2004), Evolution (Hadžhalilovic 2015),Waterlilies/Naissance des Pieuvres (Sciamma, 2007), Tomboy (Sciamma, 2011), Girlhood/Bande des Filles (Sciamma, 2014), Portrait of a Lady on Fire/Portrait d’une jeune fille en feu (Sciamma, 2019), and Petite Maman/Little Mother (Sciamma, 2021).
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FAAP, Mary Anne Jackson MD. Red Book Informe 2015 del Comite sobre Enfermedades Infecciosas, 30.a edicion. Edited by David W. Kimberlin, Sarah S. Long, and Michael T. Brady. American Academy of Pediatrics, 2015. http://dx.doi.org/10.1542/9781581109870.
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Guia autorizada del AAP a la manifestaciones, etiologia, epidemiologia, diagnostico y tratamiento de mas de 200 condiciones de la infancia. El Libro Rojo proporciona una guia basada en la evidencia a la practica de los clinicos en infecciones pediatricas y vacunas basadas en las recomendaciones del comite, asi como la experiencia combinada de los CDC, la FDA y cientos de colaboradores medicos. El Libro Rojo es una referencia esencial para pediatricos enfermedades infecciosas especialistas y pediatras generales, y es util para la medicina de familia y medicos de medicina de emergencia tambien. Los proveedores de salud publica y de salud de la escuela, medicos residentes y estudiantes tambien encontraran una fuente de alto rendimiento de la informacion pediatrica la enfermedad y la vacuna infecciosa. El libro esta dividido en secciones que cubren La inmunizacion activa y pasiva Resumenes de Enfermedades El tratamiento antimicrobiano para el tratamiento y profilaxis Cuidado de los niños en situaciones especiales Informacion y recomendaciones actualizadas que no pueden darse el lujo de estar sin ... Enfoque estandarizado para la prevencion de enfermedades a traves de las vacunas, profilaxis antimicrobiana y las practicas de control de infecciones Nuevo capitulo sobre Fiebres hemorragicas Causada por filovirus se ha añadido Nuevo capitulo sobre infecciones Parechovirus humanos se ha añadido Informacion actualizada sobre las reacciones de hipersensibilidad despues de inmunizaciones Las ultimas sobre las infecciones de transmision sexual (ITS) en los adolescentes y los niños Cobertura actualizada de actinomicosis, amebiases, arbovirus, vaginosis bacteriana, Blastocystis, candidiasis, Clostridium difficile, coronavirus, el dengue, enterovirus, Escherichia coli, Giardia intestinalis, las infecciones gonococicas, infecciones por Helicobacter pylori, enfermedad de Lyme, las infecciones meningococicas, pediculosis capitis, la tos ferina, el neumococo infecciones, rotavirus, y mas Manejo del dolor de inyeccion se ha ampliado de manera significativa Informacion actualizada sobre la hepatitis C Informacion actualizada sobre el grupo B infecciones estreptococicas Actualizado seccion sobre medicamentos para las infecciones parasitarias Significativamente capitulo revisado sobre el virus sincitial respiratorio Recomendaciones para el uso de las vacunas MMR o MMRV se han actualizado El capitulo de la Resistencia a los Antimicrobianos Antimicrobianos y Mayordomia ha broaded significativamente y actualizada Informacion actualizada sobre el VIH !Y mucho mas!
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Oats, Lynne. Principles of International Taxation. 9th ed. Bloomsbury Publishing Plc, 2023. http://dx.doi.org/10.5040/9781526526199.
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This title provides a clear introduction to international taxation and presents its material in a global context, explaining policy, legal issues and planning points central to taxation issues, primarily from the viewpoint of a multinational group of companies. It uses examples and diagrams throughout to aid the reader’s understanding and offers more in-depth material on many important areas of the subject. As well as practitioners who are less familiar with international taxation principles, this title is also used as a core text by many undergraduate and post graduate students studying business degrees. It is also widely used by those studying for the CIOT Advanced Diploma in International Taxation. Business is increasingly carried on a global scale and as such an understanding of how international taxation works is very useful for in house finance teams as well as their advisers. The 9th edition is again fully updated to cover important regulatory and legislative developments, including those in light of the ongoing OECD BEPS project implementation. Other key developments include: Progress towards a global minimum corporate tax rate to curb base erosion and tax competition (Pillar 2), eg OECD implementation framework and UK draft legislation New crypto asset reporting framework released by OECD. Ongoing impact of Covid-19 on international taxation Progress in relation to tackling tax evasion now that country by country reporting is bedding in. Further developments in European direct taxation including the debt-equity bias reduction allowance (DEBRA) and new Directive to prevent the misuse of shell entities. The updating is done by Lynne Oats, Professor of Taxation and Accounting, University of Exeter Business School, and formerly Deputy Director of the Tax Administration Research. She has managed this project since it's inception.
Book chapters on the topic "Lymne (Eng.)"
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Loadman, John, and Francis James. "The Family, the Law, and the End of a Dream." In The Hancocks of Marlborough, 60–77. Oxford University PressOxford, 2009. http://dx.doi.org/10.1093/oso/9780199573554.003.0005.
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Abstract Thomas Hancock was now, in 1835, nearly 50 and a confirmed bachelor.His rebuilt works at Goswell Mews was running smoothly,now increasingly under the guiding hand of his nephew James Lyne Hancock, while Thomasߣ principal business interests lay in Manchester.He does not seem to have had many close friends save those in business,and the majority of those were now in either Scotland or Manchester. It is to the latter that we must now turn.
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Kemp, Sandra, and Judith Squires. "Introduction." In Feminisms, 316–19. Oxford University PressNew York, NY, 1998. http://dx.doi.org/10.1093/oso/9780192892706.003.0053.
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Abstract The pieces in this section reflect upon sexuality as a domain of exploration, pleasure. and agency as well as a domain of restriction, repression, and danger. Opposing attitudes to sexuality-hetero, homo, bi, and queerwithin feminist discourses have proved so intense and enduring that it is perhaps this issue above all else that, as Lynne Segal argues, ‘produced the final and fundamental rift between feminists at The end of The 1970s and which shattered any potential unity about the nature, direction and goal of feminism’.
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Stein, Gabriele. "The French Translation Equivalents." In John Palsgrave as Renaissance Linguist, 291–338. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198235057.003.0008.
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Abstract What does Palsgrave tell us about his aims in providing his English readers with French equivalents? How much information does he want to put at their disposal? At the end of the grammatical treatment of nouns in book ill, he explains his aim and method as follows: I shall set forthe all the englysshe substantyues in our tong/ after the order of a/b/c/ and in the same lyne shewe what substantyues in the frenche tonge is of lyke signification.
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"Red rashes and erythroderma." In Paediatric Dermatology, edited by Sue Lewis-Jones and Ruth Murphy, 319–46. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198821304.003.0022.
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Red rashes and erythroderma is the longest chapter in this handbook, covering a huge number of very varied presentations and diseases with cross referral to other chapters. It commences with psoriasis and its variants and then covers most of the red viral exanthems (skin rashes) seen in children (e.g. measles), with succinct clinical descriptions and many images. It goes on to describe infestations (e.g. scabies) and skin infections from fungal causes (e.g. Tinea or ringworm); bacterial (e.g. tuberculosis and leprosy); or spirochaetal (e.g. syphilis and Lyme disease). There are also rare skin diseases described including dietary insufficiency, Kawasaki disease, and mycosis fungoides and systemic diseases such as juvenile idiopathic arthritis. Management of the rare condition erythroderma is described and can be caused by a number of factors including many skin diseases such as psoriasis; infections such as staphylococcal scalded skin syndrome and rarely in children, drugs. Finally, erythroderma, failure to thrive, and recurrent infections are briefly discussed.
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Rogovoy, Seth. "Everybody’s Got Somebody to Lean On." In Within You Without You, 183–86. Oxford University PressNew York, 2025. http://dx.doi.org/10.1093/oso/9780197627822.003.0032.
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Abstract Chapter 31 of Within You Without You, “Everybody’s Got Somebody to Lean On,” recounts the unlikely formation of the Traveling Wilburys, a rock ’n’ roll supergroup George Harrison put together that included his friends Bob Dylan, Tom Petty, Roy Orbison, and Jeff Lynne. The casual nature of the 1988 project brought out the best in these musicians, who wrote and recorded their first album as something of a lark, only to see it spawn several big hits, including Harrison’s “Handle with Care.” Shortly after the first Traveling Wilburys album was released, Roy Orbison passed away. The follow-up album released by the group two years later had its fun moments, but without Orbison’s ethereal vocal contributions, it ultimately failed to ignite. In the end, the Traveling Wilburys were more a legend than a band.
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Karras, David J. "Miscellaneous Infectious Syndromes: Lyme Carditis, Human Immunodeficiency Virus-Associated, and Chagas Disease." In ECG in Emergency Medicine and Acute Care, 324–27. Elsevier, 2005. http://dx.doi.org/10.1016/b978-0-323-01811-1.50077-8.
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Wells, H. G. "The Astonishing Communication of Mr Julius Wendigee." In The First Men in the Moon, edited by Simon J. James. Oxford University Press, 2017. http://dx.doi.org/10.1093/owc/9780198705048.003.0022.
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When I had finished my account of my return to the earth at Littlestone I wrote, ‘The End,’ made a flourish, and threw my pen aside, fully believing that the whole story of the First Men in the Moon was done. Not only had I done this, but I had placed my manuscript in the hands of a literary agent, had permitted it to be sold, had seen the greater portion of it appear in the Strand Magazine, and was setting to work again upon the scenario of the play I had commenced at Lympne before I realised that the end was not yet. And then, following me from Amalfi to Algiers, there reached me (it is now about six months ago) one of the most astounding communications I have ever been fated to receive. Briefly, it informed me that Mr Julius Wendigee, a Dutch electrician, who has been experimenting with certain apparatus akin to the apparatus used by Mr Tesla in America,* in the hope of discovering some method of communication with Mars, was receiving day by day a curiously fragmentary message in English, which was indisputably emanating from Mr Cavor in the moon.
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Heidbuchel, Hein. "Bradycardia in athletes: clinical evaluation and management." In ESC CardioMed, edited by Giuseppe Boriani, 1971–73. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0457.
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Sinus bradycardia is very common in athletes. Recent evidence has shown that vagal hypertonia is not so much the mechanism behind this physiological adaptation, but rather intrinsic structural and ionic channel remodelling of the sinus node. Some athletes may present with extreme forms of bradycardia, such as a resting sinus rhythm of less than 30 beats per minute or sinus pauses of longer than 3 s. Even if asymptomatic, one may wonder how far this can still be considered ‘physiological’, since it is known that former athletes have a higher likelihood for the development of symptomatic bradycardia and the need for pacemaker implantation. Whereas asymptomatic athletes can participate in all sports, temporary cessation in those with symptoms is warranted to gauge resolution of bradycardia. If persistently symptomatic, pacemaker implantation needs to be considered. In those with extreme bradycardia but who are asymptomatic, a more intensified follow-up is recommended after exclusion of underlying causes (e.g. infiltrative cardiomyopathy, Lyme disease, or sarcoidosis).
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Ingleby, Matthew, and Matthew P. M. Kerr. "Introduction." In Coastal Cultures of the Long Nineteenth Century, 1–26. Edinburgh University Press, 2018. http://dx.doi.org/10.3366/edinburgh/9781474435734.003.0001.
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In the latter part of the eighteenth century and at the beginning of the nineteenth, the British cultural imagination turned to coasts. Prior to this period, coasts tended to be thought of as uninviting, even dangerous, places – ‘repulsive’, according to Alain Corbin.1 A compound of interlinked developments – in medicine, in aesthetics, in leisure, in law, in military strategy, for example – altered the prevailing mood, however, and during the long nineteenth century, the coast was visited more often, and by an increasingly diverse collection of people. This swell of interest in the littoral meant that coasts began to function as zones of cultural and commercial interchange. In part, this was because coasts became places of literal intermingling, where geologists and quack doctors, composers and painters, holidaymakers and recluses might meet intentionally or accidentally. Geological tourists followed Mary Anning to Lyme Regis in droves to purchase or discover for themselves sea-shells by the sea-shore. And towards the end of the nineteenth century, artists formed colonies at Pont-Aven, St Ives and elsewhere....
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Sanz, Marta Gonzalez, and Caoimhe Nic Fhogartaigh. "Zoonotic Infections." In Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198801740.003.0046.
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The term zoonosis comes from the Greek: ζῷον (zoon) ‘animal’ and νόσος (nosos) ‘sickness’, and means an infection transmissible from animals to humans. Infected animals can be symptomatic or asymptomatic, and humans usually become accidental hosts through close contact with the reservoir animal. Six out of ten infections in humans globally are spread from animals, and 75% of emerging infections are zoonotic. Some occur worldwide e.g. E. coli O157:H7, whereas some are more restricted geographically, e.g. Ebola virus. The highest burden is in developing countries. There are various classifications of zoonoses. ● Causative pathogen: bacterial (anthrax, non-typhoidal Salmonelloses); viral (rabies, Yellow Fever, hantaviruses); parasitic (hookworm, Giardia, toxoplasmosis); fungal (dermatophytes, histoplasmosis); or prion (new-variant Creutzfeldt-Jakob disease). ● Mode of transmission (see Section 35.3 and Table 35.1 below) ● Distribution: endemic zoonoses are continually present in a population (e.g. leptospirosis, brucellosis); epidemic zoonoses occur intermittently (e.g. anthrax, Rift Valley Fever); emerging zoonoses are new infections, or existing infections that are increasing in incidence or geographical range (e.g. Nipah virus, Middle East Respiratory Syndrome coronavirus). ● Direct contact: infectious particles are present on an infected animal, in its body fluids, and in its excreta. Q fever, caused by Coxiella burnetii, and brucellosis may be acquired by direct contact with infected animals, particularly during parturition; cat-scratch disease caused by Bartonella henselae, and Pasteurella spp. may be acquired by bites or scratches from cats, and rabies from canine bites. Many zoonoses are also transmitted via indirect animal contact through exposure to soil or water contaminated by infectious material, e.g. leptospirosis may be acquired when water contaminated with infected rats’ urine comes into contact with broken skin or mucous membranes. ● Ingestion: infection occurs by ingesting contaminated food or water, e.g. unpasteurized milk, poorly processed or undercooked meat, or by eating/ drinking after handling animals without handwashing. Listeria, bovine tuberculosis, and brucellosis may be transmitted by unpasteurized milk and dairy produce; Hepatitis E through processed pork, and Ebola and Marburg through bushmeat. ● Vector-borne: infection is transmitted through a biting arthropod vector. Examples include West Nile Virus and Japanese encephalitis from mosquitoes, Lyme disease, tick-borne encephalitis, and Rocky Mountain Spotted Fever from ticks, and Rickettsia typhi from rat fleas.