Relevant bibliographies by topics / Lumbar Spine Bone Mineral Density

Academic literature on the topic 'Lumbar Spine Bone Mineral Density'

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Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "Lumbar Spine Bone Mineral Density"

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Zaytseva, E. M., A. V. Smirnov, L. I. Alekseeva, E. M. Zaitseva, A. V. Smirnov, and L. I. Alekseeva. "Interrelation of bone mineral density with kneeosteoarthrosis." Osteoporosis and Bone Diseases 14, no. 1 (April 15, 2011): 19–20. http://dx.doi.org/10.14341/osteo2011119-20.

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Association of bone mineral density (BMD) of axial skeleton with age of the disease onset as well as with clinical traits and instrumental investigation findings has been studied in osteoarthritic patients. 116 females with primary knee OA, 74 ofwhich exhibited normal or increased BMD at lumbar spine and 42, with osteoporosis were included in the study. Knee joint pain was measured using visual analog scale (VAS). All the patients were subjected to X-ray analysis of their knee joints at two sites (OA stage was determined according to Kellgren-Lawrence scale), densitometry at lumbar spine and proximal femur using QDR-4500W (Hologic), MRT, and ultrasonography of the knee joints. We determined that the increasedBMD at lumbar spine was associated with early OA onset, more pronounced X-ray changes in the knee joints and higher frequency of varus deformation development in tibial bones.
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Paiva, Lúcia Costa, Silvana Filardi, Aarão Mendes Pinto-Neto, Adil Samara, and João Francisco Marques Neto. "Impact of degenerative radiographic abnormalities and vertebral fractures on spinal bone density of women with osteoporosis." Sao Paulo Medical Journal 120, no. 1 (January 3, 2002): 09–12. http://dx.doi.org/10.1590/s1516-31802002000100003.

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CONTEXT: Measurements of bone density taken by dual-energy x-ray absorptiometry are the most accurate procedure for the diagnosis of osteoporosis. This procedure has the disadvantage of measuring the density of all mineral components, including osteophytes, vascular and extra vertebral calcifications. These alterations can influence bone density results and densitometry interpretation. OBJECTIVE: To correlate radiography and densitometry findings from women with osteoporosis, analyzing the influence of degenerative processes and vertebral fractures on the evaluation of bone density. DESIGN: Retrospective study. SETTING: Osteoporosis outpatients' clinic at Hospital das Clínicas, Universidade Estadual de Campinas. PARTICIPANTS: Ninety-six postmenopausal women presenting osteoporosis diagnosed by bone density. MAIN MEASUREMENTS: Bone mineral density of the lumbar spine and femoral neck were measured by the technique of dual-energy x-ray absorptiometry, using a LUNAR-DPX densitometer. Fractures, osteophytes and aortic calcifications were evaluated by simple x-rays of the thoracic and lumbar spine. RESULTS: The x-rays confirmed vertebral fractures in 41.6%, osteophytes in 33.3% and calcifications of the aorta in 30.2%. The prevalence of fractures and aortic calcifications increased with age. The mean bone mineral density was 0.783g/cm² and the mean T-score was --3.47 DP. Neither fractures nor aortic calcifications had significant influence on bone mineral density (P = 0.36 and P = 0.09, respectively), despite the fractured vertebrae having greater bone mineral density (P < 0.02). Patients with lumbar spine osteophytes showed greater bone mineral density (P = 0.04). Osteophytosis was associated with lumbar spine bone mineral density after adjustment for fractures and aortic calcifications by multiple regression (P = 0.01). CONCLUSION: Osteophytes and lumbar spine fractures can overestimate bone density interpretation. The interpretation of densitometry results should be carried out together with the interpretation of a simple lumbar spine x-ray in elderly women.
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Garcia Alves Junior, Paulo Alonso, Daniel Luis Gilban Schueftan, Laura Maria Carvalho de Mendonça, Maria Lucia Fleiuss Farias, and Izabel Calland Ricarte Beserra. "Bone Mineral Density in Children and Adolescents with Congenital Adrenal Hyperplasia." International Journal of Endocrinology 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/806895.

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Chronic glucocorticoid therapy is associated with reduced bone mineral density. In paediatric patients with congenital adrenal hyperplasia, increased levels of androgens could not only counteract this effect, but could also advance bone age, with interference in the evaluation of densitometry. We evaluate bone mineral density in paediatric patients with classic congenital adrenal hyperplasia taking into account chronological and bone ages at the time of the measurement. Patients aged between 5 and 19 years underwent radiography of the hand and wrist followed by total body and lumbar spine densitometry. Chronological and bone ages were used in the scans interpretation. In fourteen patients, mean bone mineral densityZ-score of total body to bone age was −0.76 and of lumbar spine to bone age was −0.26, lower than those related to chronological age (+0.03 and +0.62, resp.). MeanZ-score differences were statistically significant (P=0.004for total body andP=0.003for lumbar spine). One patient was classified as having low bone mineral density only when assessed by bone age. We conclude that there was a reduction in the bone mineral densityZ-score in classic congenital adrenal hyperplasia paediatric patients when bone age was taken into account instead of chronological age.
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Lestari, Sri, and Rini Widyaningrum. "Hubungan fraksi area trabekula anterior mandibula dengan kepadatan tulang lumbar spine untuk deteksi dini osteoporosis." Majalah Kedokteran Gigi Indonesia 3, no. 1 (October 31, 2017): 43. http://dx.doi.org/10.22146/majkedgiind.13207.

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The relationship of anterior mandible trabecular area with bone mass density of lumbar spine for early detection of osteoporosis. Bone mineral density is an indicator of osteoporosis, including the bone mineral density of lumbar spine. The decrease of lumbar spine bone mass density will cause an alteration in another site, including the mandibular. The aim of this research is to determine the predictor of lumbar spine bone mineral density using trabecular bone image of anterior mandible on periapical radiographs. The research was conducted by extracting the area fraction at mandible trabecular bone using digital periapical radiograph from 25 subjects. Canny edge detection was used in digital image processing for each radiograph. The regions of interest were selected from the image obtained by canny edge detection, so that the area fraction could be measured. A linier regression test was applied to determine a relationship between the area fractions of mandible trabecular bone with the bone mineral density of lumbar spine. The result of linear regression test showed that the area fraction of mandible trabecular bone had a moderate negative correlation with bone mass density of lumbar spine (α = 0.046; R = -0.403). The direction of the correlation was negative (b = -0.145). The area fraction of mandible trabecular bone on periapical radiographs could be used as the predictor for bone mass density of lumbar spine.ABSTRAKKepadatan tulang merupakan indikator osteoporosis, salah satu diantaranya adalah kepadatan tulang pada lumbar spine. Penurunan kepadatan tulang pada lumbar spine mempengaruhi kondisi tulang lain, termasuk tulang rahang bawah (mandibula). Tujuan penelitian ini adalah untuk menentukan prediktor densitas mineral tulang menggunakan citra radiograf periapikal tulang trabekula pada regio anterior rahang bawah. Penelitian dilakukan dengan ekstraksi fraksi area tulang trabekula mandibula yang tercitrakan pada radiograf periapikal digital dari 25 subjek. Pengolahan citra digital pada radiograf periapikal dilakukan dengan menggunakan metode deteksi tepi canny terhadap masing-masing citra radiograf. Region of Interest diseleksi dari citra hasil deteksi canny, sehingga dapat dilakukan pengukuran fraksi area. Uji regresi linier dilakukan untuk mengetahui hubungan antara nilai fraksi area trabekula mandibula dengan tingkat kepadatan tulang pada lumbar spine. Hasil uji regresi linier menunjukkan bahwa nilai fraksi area trabekula mandibula berkorelasi negatif dengan kepadatan tulang dengan kekuatan sedang (α = 0,046; R = -0,403). Adapun arah korelasi antara nilai fraksi area trabekula mandibula dengan kepadatan tulang adalah negatif (b = -0,145). Fraksi area tulang trabekula pada citra radiograf periapikal dapat digunakan sebagai prediktor kepadatan tulang pada lumbar spine.
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Blake, Jennifer M., Eamonn D. Ryan, Lesley F. Beaumont, and Colin E. Webber. "Changes in spine and radius bone density during long-term hormone replacement." Canadian Journal of Physiology and Pharmacology 77, no. 7 (August 1, 1999): 505–9. http://dx.doi.org/10.1139/y99-051.

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Lumbar spine and mid-radius bone mineral density was measured repeatedly in 48 postmenopausal women who completed 7 years of taking either a 500 mg·day-1 calcium supplement (n = 22) or calcium supplementation with hormone replacement therapy. The hormone replacement was either a low dose (n = 15) or a moderate dose (n = 11) regime. The purpose of the measurements was to establish the long-term pattern of change in bone mineral mass produced by continued hormone replacement. The calcium-only group lost bone mineral mass at the radius, while at the spine, bone was preserved. Low dose hormone replacement preserved radius bone. Moderate dose replacement increased bone mineral mass at the spine and preserved radius bone.Key words: calcium supplementation, long-term hormone replacement, lumbar spine bone mineral density, radius bone mineral density.
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Luo, Yixue, Chenyu Luo, Yuhui Cai, Tianyun Jiang, Tianhong Chen, Wenyue Xiao, Junchao Guo, and Yubo Fan. "Analysis of Bone Mineral Density/Content of Paratroopers and Hoopsters." Journal of Healthcare Engineering 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/6030624.

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The different mechanical stimulus affects the bone mass and bone strength. The aim of this study was to investigate the effect of landing posture of the hoopster and paratrooper on the bone mass. In this study, 39 male participants were recruited including 13 paratroopers, 13 hoopsters, and 13 common students (control groups). Bone area (BA), BMD and BMC of calcaneus, and 1–5th of the metatarsus, hip, and lumbar spine (L1–L4) were measured by the dual-energy X-ray absorptiometry. Also, the vertical ground reaction forces (GRFs) of hoopsters and paratroopers were measured by the landing of 1.2 m 3D force platform. BA of hoopsters at the calcaneus, lumbar spine, and hip were significantly higher than the control group. The lumbar spine, hip, calcaneus, the 1st and 2nd metatarsals, BMC of paratroopers, and control groups were significantly lower than hoopsters. BMD of the lumbar spine, hip, and right and left femoral necks in hoopsters were significantly higher than the other participants. BMC and BMD of lower limber showed no significant difference between paratroopers and the control group. Besides, peak GRFs of paratroopers (11.06 times of BW) were significantly higher than hoopsters (6.49 times of BW). The higher GRF in the landing train is not always in accordance with higher BMD and BMC. Variable loads in hoopsters can improve bone remodeling and play an important role in bone expansions for trabecular bones. This will be considered by the method of training to prevent bone loss.
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Kenis, Vladimir M., Andrei V. Sapogovskiy, Tatyana N. Prokopenko, Artur N. Bergaliev, Stanislav V. Ivanov, and Tatyana I. Kiseleva. "Bone mineral density in children with cerebral palsy and Spina Bifida treated with ibandronate." Pediatric Traumatology, Orthopaedics and Reconstructive Surgery 8, no. 2 (July 1, 2020): 129–36. http://dx.doi.org/10.17816/ptors33961.

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Background. Bisphosphonates have become a common method for the prevention and treatment of osteoporosis in children with neuromuscular diseases. Aim. The aim of this study was to assess the mid-term changes of bone mineral density in patients with cerebral palsy and spina bifida treated with ibandronic acid. Materials and methods. Thirty-four patients were examined and treated: 19 children with cerebral palsy (GMFCS levels IIIIV) and 15 children with spina bifida (thoracic and upper lumbar neurosegmental levels), mean age 9.8 2.9 years. Ibandronic acid was administered to all patients (3 consecutive intravenous infusions, 0.1 mg/kg every 34 months). The assessment of bone mineral density was performed using dual-energy X-ray absorptiometry. Results. The Z-score increased from 2.55 to 2.1 (total body less head), and from 2.7 to 1.65 (lumbar spine). Improvement of the Z-score for the lumbar spine was noted after the first infusion, and for the whole body after the first two infusions. Conclusion. Ibandronic acid infusions improved the bone mineral density in children with cerebral palsy and spina bifida for both the whole body and the lumbar spine. Given the data obtained, weight-bearing exercises can be recommended three months after the first infusion, and dynamic exercises can be performed, preferably after six months.
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Sheth, Raj D., Gerald R. Hobbs, Jack E. Riggs, and Sharon Penney. "Bone Mineral Density in Geographically Diverse Adolescent Populations." Pediatrics 98, no. 5 (November 1, 1996): 948–51. http://dx.doi.org/10.1542/peds.98.5.948.

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Objective. Measure bone mineral density (BMD) in healthy Newfoundland adolescents and determine whether BMD is comparable in geographically diverse adolescent populations. Study design. Lumbar spine BMD was measured by dual-energy radiograph absorptiometry in 26 healthy adolescents between ages 8 and 20 years. The age and gender of these subjects were used to predict BMD from equations derived from normative BMD data in six geographically diverse populations. The actual BMD value obtained for each subject was then compared with each of the six predicted BMD values for that adolescent using the Wilcoxon signed-ranks test. Results. Actual lumbar spine BMD in Newfoundland adolescents was not significantly different from that predicted by age and gender if they were from California, Finland, France, North Carolina, and Switzerland. Only the prediction based on the Spanish population resulted in a 4% greater BMD than was actually measured in the Newfoundland adolescents. Conclusions. Lumbar spine BMD measurements for most healthy adolescent populations, as in adults, are comparable despite geographic diversity. Thus, generation of institution-specific normative BMD data may not be necessary for most adolescent populations.
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Trombetti, Andrea, Laura Richert, François R. Herrmann, Thierry Chevalley, Jean-Daniel Graf, and René Rizzoli. "Selective Determinants of Low Bone Mineral Mass in Adult Women with Anorexia Nervosa." International Journal of Endocrinology 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/897193.

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We investigated the relative effect of amenorrhea and insulin-like growth factor-I (sIGF-I) levels on cancellous and cortical bone density and size. We investigated 66 adult women with anorexia nervosa. Lumbar spine and proximal femur bone mineral density was measured by DXA. We calculated bone mineral apparent density. Structural geometry of the spine and the hip was determined from DXA images. Weight and BMI, but not height, as well as bone mineral content and density, but not area and geometry parameters, were lower in patients with anorexia nervosa as compared with the control group. Amenorrhea, disease duration, and sIGF-I were significantly associated with lumbar spine and proximal femur BMD. In a multiple regression model, we found that sIGF-I was the only significant independent predictor of proximal femur BMD, while duration of amenorrhea was the only factor associated with lumbar spine BMD. Finally, femoral neck bone mineral apparent density, but not hip geometry variables, was correlated with sIGF-I. In anorexia nervosa, spine BMD was related to hypogonadism, whereas sIGF-I predicted proximal femur BMD. The site-specific effect of sIGF-I could be related to reduced volumetric BMD rather than to modified hip geometry.
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Rutherford, O. M. "Spine and total body bone mineral density in amenorrheic endurance athletes." Journal of Applied Physiology 74, no. 6 (June 1, 1993): 2904–8. http://dx.doi.org/10.1152/jappl.1993.74.6.2904.

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Lumbar spine, total body, and regional bone mineral densities (BMDs) were measured in eumenorrheic and amenorrheic runners and triathletes by using dual-energy X-ray absorptiometry (Lunar DPX). Values were also compared with age- and weight-matched reference data from the Lunar British database. The amenorrheic group had significantly lower lumbar spine (P = 0.003), arm (P = 0.018), trunk (P = 0.014), and total spine (P < 0.0001) BMDs compared with the eumenorrheic group and significantly lower lumbar (P = 0.002) and total spine (P < 0.001) values compared with the reference controls. Leg (P = 0.009) and arm (P < 0.001) densities were significantly higher than controls. All regions, apart from the lumbar spine, were significantly higher in the eumenorrheic group compared with the reference group. There were no within-group differences for the runners and triathletes. Compared with the eumenorrheic athletes, the amenorrheic women had significantly later age of menarche (P = 0.0032). The type of physical activity undertaken by these athletes can compensate for the loss of menses at the majority of skeletal sites with the exception of the spine.
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Dissertations / Theses on the topic "Lumbar Spine Bone Mineral Density"

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López, Picazo Mirella. "3D subject-specific shape and density modeling of the lumbar spine from 2D DXA images for osteoporosis assessment." Doctoral thesis, Universitat Pompeu Fabra, 2019. http://hdl.handle.net/10803/666513.

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Osteoporosis is the most common bone disease, with a significant morbidity and mortality caused by the increase of bone fragility and susceptibility to fracture. Dual Energy X-ray Absorptiometry (DXA) is the gold standard technique for osteoporosis and fracture risk evaluation at the spine. However, the standard analysis of DXA images only provides 2D measurements and does not differentiate between bone compartments; neither specifically assess bone density in the vertebral body, which is where most of the osteoporotic fractures occur. Quantitative Computed Tomography (QCT) is an alternative technique that overcomes limitations of DXA-based diagnosis. However, due to the high cost and radiation dose, QCT is not used for osteoporosis management. In this thesis, a method providing a 3D subject-specific shape and density estimation of the lumbar spine from a single anteroposterior DXA image is proposed. The method is based on a 3D statistical shape and density model built from a training set of QCT scans. The 3D subject-specific shape and density estimation is obtained by registering and fitting the statistical model onto the DXA image. Cortical and trabecular bone compartments are segmented using a model-based algorithm. 3D measurements are performed at different vertebral regions and bone compartments. The accuracy of the proposed methods is evaluated by comparing DXA-derived to QCT-derived 3D measurements. Two case-control studies are also performed: a retrospective study evaluating the ability of DXA-derived 3D measurements at lumbar spine to discriminate between osteoporosis-related vertebral fractures and control groups; and a study evaluating the association between DXA-derived 3D measurements at lumbar spine and osteoporosis-related hip fractures. In both studies, stronger associations are found between osteoporosis-related fractures and DXA-derived 3D measurements compared to standard 2D measurements. The technology developed within this thesis offers an insightful 3D analysis of the lumbar spine, which could potentially improve osteoporosis and fracture risk assessment in patients who had a standard DXA scan of the lumbar spine without any additional examination.
La osteoporosis es la enfermedad ósea más común, con una morbilidad y mortalidad significativas causadas por el aumento de la fragilidad ósea y la susceptibilidad a las fracturas. La absorciometría de rayos X de energía dual (DXA, por sus siglas en inglés) es la técnica de referencia para la evaluación de la osteoporosis y del riesgo de fracturas en la columna vertebral. Sin embargo, el análisis estándar de las imágenes DXA solo proporciona mediciones 2D y no diferencia entre los compartimentos óseos; tampoco evalúa la densidad ósea en el cuerpo vertebral, que es donde se producen la mayoría de las fracturas osteoporóticas. La tomografía computarizada cuantitativa (QCT, por sus siglas en inglés) es una técnica alternativa que supera las limitaciones del diagnóstico basado en DXA. Sin embargo, debido al alto costo y la dosis de radiación, la QCT no se usa para el diagnóstico de la osteoporosis. En esta tesis, se propone un método que proporciona una estimación personalizada de la forma 3D y la densidad de la columna vertebral en la zona lumbar a partir de una única imagen DXA anteroposterior. El método se basa en un modelo estadístico 3D de forma y densidad creado a partir de un conjunto de entrenamiento de exploraciones QCT. La estimación 3D personalizada de forma y densidad se obtiene al registrar y ajustar el modelo estadístico con la imagen DXA. Se segmentan los compartimentos óseos corticales y trabeculares utilizando un algoritmo basado en modelos. Se realizan mediciones 3D en diferentes regiones vertebrales y compartimentos óseos. La precisión de los métodos propuestos se evalúa comparando las mediciones 3D derivadas de DXA con las derivadas de QCT. También se realizan dos estudios de casos y controles: un estudio retrospectivo que evalúa la capacidad de las mediciones 3D derivadas de DXA en la columna lumbar para discriminar entre sujetos con fracturas vertebrales relacionadas con la osteoporosis y sujetos control; y un estudio que evalúa la asociación entre las mediciones 3D derivadas de DXA en la columna lumbar y las fracturas de cadera relacionadas con la osteoporosis. En ambos estudios, se encuentran asociaciones más fuertes entre las fracturas relacionadas con la osteoporosis y las mediciones 3D derivadas de DXA en comparación con las mediciones estándar 2D. La tecnología desarrollada dentro de esta tesis ofrece un análisis en 3D de la columna lumbar, que podría mejorar la evaluación de la osteoporosis y el riesgo de fractura en pacientes que se sometieron a una exploración DXA estándar de la columna lumbar sin ningún examen adicional.
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Darlington, Sarah Elizabeth. "Effect of intra-abdominal fat on the accuracy of DXA lumbar spine bone mineral density measurement using DXA body composition measurements." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/44881/.

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In the diagnosis of osteoporosis, dual-energy X-ray absorptiometry (DXA) is the accepted method for measuring bone mineral density (BMD) due to its good precision. However, accuracy is compromised by two assumptions: (1) the body is composed of only soft tissue and bone mineral and (2) the composition of tissue overlying bone is equal to that adjacent to bone. To diagnosis osteoporosis, BMD is compared to that of a young healthy population to calculate a T-score. BMD is normal if T-score>-1 and osteoporotic if < -2.5. The aim of this study was to use DXA whole body (WB) scans to quantify variation in abdominal fat thickness and to explore whether this information could be used to improve the accuracy of lumbar spine (LS) BMD measurement. Relevant data were extracted from archived DXA images for groups of patients who had received both LS and WB scans. LS BMD increased with the width of the associated soft tissue baseline and BMD was correlated with fat thickness within the baseline. For individuals, the bone mineral equivalence of the difference in fat thickness between a standard width baseline and a region over the spine corresponded to a maximum T-score difference of 0.6. However, the average for the groups gave a T-score difference of 0.2. The predicted inaccuracy in LS BMD measurement resulting from a non-uniform fat distribution was within 0.013 g/cm2 for groups and 0.017 g/cm2 for individuals. From these measurements, errors in BMD of up to 6% and 3% for a standard width baseline were observed for individuals and groups respectively. In the majority of patients, errors introduced by a non-uniform distribution of fat are unlikely to cause a mis-diagnosis. However, significant errors may occur in certain individuals. The clinical application of the proposed method to quantify errors in BMD requires further investigation
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Altunsoz, Omur Serdal. "Determine The Effects Of Long Term Playing Soccer On The Degeneration Of Lumbar Spine." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607487/index.pdf.

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The main purpose of this study was to determine whether playing soccer at high intensity training for a long period causes degeneration of the lumbar spine or not. This degeneration may occur without any symptoms or low back pain. Results of the present study were discussed in the framework of lumbar disc degeneration, trunk strength, lumbar and hip bone mineral density, trunk flexibility, activity MET scores for active and veteran soccer groups. There have been four subject groups in this study (15 active soccer players, 15 sedentary participants, 14 veteran soccer players, 13 sedentary participants). The BMD was measured in anterior-posterior view with a second-generation dual energy X-ray absorptiometry (DEXA) device. Isokinetic trunk strength data were recorded with the Biodex System Dynamometer (Biobex Medical Inc, Shirly, NY) at the 60º
/sec and 120º
/sec. Plain lateral radiographs were taken. The presence of degenerative changes of each lumbar vertebra was determined by using the Kellgren and Lowrence Score. A modified Schober test was used to measure lumbar flexion. Findings of the study demonstrated that veteran soccer players displayed greater lumbar disc degeneration than other groups. Moreover, v active soccer group had more BMD than other groups, but the veteran group&
#8217
s BMD results were not different while comparing the control participants. Isokinetic test findings of the current study, trunk extension strength at 60/sec was significantly higher in active 1st group players than 2nd group participants, but there were no significant differences between the 1st group and 2nd group in terms of trunk flexion strength and agonist/antagonist ratio at 60/sec. In conclusion, Findings of the study support the main hypothesis that playing soccer at high intensity training at a long period of time may cause lumbar spine degeneration. Degeneration may occur without low back symptoms. Moreover, results supported the idea that Soccer can be accepted an impact loading sport that are to keep or accelerate bone mineral density. At last, having abnormal trunk extension strength while playing actively may cause lumbar disc degeneration on the spine at later years. A similar study should be carried out with a larger number of subjects, and longitudinal studies should be designed to examine the factors that effect the degeneration on the lumbar spine.
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Strong, J. Eric. "Effects of Different Jumping Programs on Hip and Spine Bone Mineral Density in Pre-Menopausal Women." BYU ScholarsArchive, 2004. https://scholarsarchive.byu.edu/etd/667.

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Sixty premenopausal women (age 25-50) finished a 16 week randomized controlled trial looking at the effects of different jump programs on hip and spine bone mineral density (BMD). Subjects were randomly assigned to a control group or one of two jumping groups. The Jump 10 group performed 10 jumps with 30 seconds of rest between jumps, twice daily, while the Jump 20 group performed the same protocol but with 20 jumps. At 8 weeks, BMD percent change (%Δ) at the hip was significantly different among groups when age, weight change, and subject compliance were simultaneously adjusted. In particular, the Jump 20 group had a greater %Δ in hip BMD compared to controls. However, %Δ in BMD for the neck of the hip (NOH), trochanter, or spine was not different among groups at 8 weeks. Following 16 weeks of jumping, BMD %Δ at the total hip and trochanter were significantly different among groups after adjusting for all covariates. Specifically, at the hip and trochanter, the Jump 10 and Jump 20 groups showed significantly greater %Δ in BMD compared to controls. There were no significant differences among groups for the BMD %Δ at NOH or spine at 16 weeks. Within-group analyses revealed no significant changes from baseline to 16 weeks for the jumping groups, but controls lost significant BMD. In conclusion, after 16 weeks of high-impact jump training, BMD at the hip and trochanter can be improved by jumping 10 or 20 times, twice daily, with 30 seconds of rest between each jump, compared to controls.
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Whitmarsh, Tristan. "3D reconstruction of the proximal femur and lumbar vertebrae from dual-energy x-ray absorptiometry for osteoporotic risk assessment." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/94492.

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In this thesis a method was developed to reconstruct both the 3D shape and the BMD distribution of bone structures from Dual-energy X-ray Absorptiometry (DXA) images. The method incorporates a statistical model built from a large dataset of Quantitative Computed Tomography (QCT) scans together with a 3D-2D intensity based registration process. The method was evaluated for its ability to reconstruct the proximal femur from a single DXA image. The resulting parameters of the reconstructions were subsequently evaluated for their hip fracture discrimination ability. The reconstruction method was finally extended to the reconstruction of the lumbar vertebrae from anteroposterior and lateral DXA, thereby incorporating a multi-object and multi-view approach. These techniques can potentially improve the fracture risk estimation accuracy over current clinical practice.
En esta tesis se desarrolló un método para reconstruir tanto la forma 3D de estructuras óseas como la distribución de la DMO a partir de una sola imagen de DXA. El método incorpora un modelo estadístico construido a partir de una gran base de datos de QCT junto con una técnica de registro 3D-2D basada en intensidades. Se ha evaluado la capacidad del método para reconstruir la parte proximal del fémur a partir de una imagen DXA. Los parámetros resultantes de las reconstrucciones fueron evaluados posteriormente por su capacidad en discriminar una fractura de cadera. Por fin, se extendió el método a la reconstrucción de las vértebras lumbares a partir de DXA anteroposterior y lateral incorporando así un enfoque multi-objeto y multi-vista. Estos técnicas pueden potencialmente mejorar la precisión en la estimación del riesgo de fractura respecto a la estimación que ofrece la práctica clínica actual.
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Lin, Yun-Chen, and 林芸甄. "The Relationship among Bone Turnover Markers, Physical Activity and Lumbar Spine Bone Mineral Density in Group-Living Elderly." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/10242668614682838908.

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碩士
輔仁大學
食品營養學系
92
With the change in social environment and the function of the household, the elderly population residing in elderly accommodation institutions or elderly residential settings has risen progressively. International research in development of osteoporosis has expanded rapidly. However there is limited information regarding the evaluation of bone health for the elderly above 65 years old in Taiwan. Therefore, the study recruited 125 group-living elderly from Yi-Yuan and Tsui-Po elderly accommodation institutions. A Hologic QDR-1500 dual-energy X-ray absorptometry was used to measure the bone mineral density (BMD) of the lumbar spine (LS) of subjects. Total daily physical activity (TDPA) was assessed by a nutrition screening questionnaire. Serum bone turnover markers, including bone-specific alkaline phosphatase (BAP), osteocalcin (OC), type I C-terminal propeptide (CICP) and pyridinoline (Pyd) were measured to assess the variable status of bone turnover in subjects. The average age of surveyed subjects was 79.1 ± 5.6 years. The average BMD at the LS of male and female elderly were 1.004 ± 0.191 g/cm2 and 0.833 ± 0.153 g/cm2, respectively. The prevalence of osteoporosis and osteopenia were 17.5％ and 44.4％ among male elderly and were 43.6％ and 43.6％ among female elderly respectively. The state of poor bone health was 61.9％ in male elderly and 87.1％ in female elderly. The mean concentrations of the BAP and Pyd in summer of the female elderly were 28.1％ and 23.9％ higher compared with adult reference values. The values of the BAP and Pyd of the male elderly were distributed within adult reference range. The mean concentration of OC in summer was increased in 83.1％ of the male and 92.5％ of the female elderly compared with reference values for adults. The mean concentration of CICP in summer was lower in 40.6％ of the male and 25.4％ of the female elderly, as compared with adult reference values. The mean value of bone turnover index for male and female elderly in winter was 2.4 times and 1.3 times than of the values in summer, respectively. The result indicated that bone turnover, as assessed by specific bone markers, was accelerated during winter in both sexes. The average TDPA of subjects was 26.8 ± 2.2 METs/day. The physical activity level ratio (TDPA/basal energy expenditure) of subjects was 1.39 ± 0.13. The degree of the positively correlation between BMD of the LS and awaken physical activity (APA) was enhanced after METs or kcal for the sleep was subtracted from TDPA. Moreover, we found that CICP and b-quotient increased with increasing TDPA (METs/day) in male elderly. We found decreased level of Pyd with increasing TDPA (METs/day) in male elderly. The state of bone health of most elderly was classified as osteopenia or osteoporosis. Our findings with respect to the differences in bone turnover markers between male and female elderly indicated that bone loss probably is a result of insufficient type I collagen synthesis in male elderly, whereas of excessive bone resorption in female elderly. Increase in physical activity may be positively correlated with type I collagen synthesis and negatively correlated with bone resorption. Key words: osteoporosis, group-living elderly, bone mineral density, BAP, OC, CICP, Pyd, physical activity
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Kohut, June R. "Enhanced lumbar spine bone mineral content and bone mineral density in SGA piglets fed arachidonic acid and docosahexaenoic acid are modulated by birth weight." 2005. http://hdl.handle.net/1993/18088.

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YEH, HSIU-CHEN, and 葉秀宸. "Establishing High-Accuracy Bone Mineral Density Measurement Technique for Lateral Lumbar Spine using Dual Energy X-ray Absorptiometry." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/rfw4jc.

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碩士
慈濟科技大學
放射醫學科學研究所
107
The purpose of this study was to establish a measurement technique for high-accuracy positioning of lumbar spine bone density. Using DEXA to measure the different parameters for analyzing. The study is divided into two parts. The first part is the tissue simulation prosthesis scan to explore whether the DEXA scan corresponds to the results of different physical density objects. The second part is the phantom of human body scanning, which is related to experience correlation, scanning method correlation and placement error. The current common scanning method is AP lumbar scan, and there is fewer lateral position to be comparing. The spine fracture mostly occurred in the vertebral body and position of lateral lumbar vertebrae ROI only analysis the vertebral body. We suggest that is more suitable to evaluate the osteoporosis using lateral body of lumbar spine. Under the set variables in the experiment, it was found that different experience operators, different center points, different instruments and placement angle effects, etc., there were significant differences in BMD measurement results (p<0.05), and the first part of the tissue simulation prosthesis two The correlation coefficient between the placement method and the physical density was 0.907 and 0.914, respectively. In addition, the distance between the measured object and the detector was also significantly different (P<0.05). The above results can be applied to the re-education and proficiency audit of the radiologist to improve the clinical measurement accuracy of the lateral lumbar vertebrae.
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"Evaluation of lumbar spine vertebral fracture in Hong Kong Chinese elderly with reduced bone mineral density: 評估香港華裔長者腰椎椎體骨折與骨密度(BMD)降低的關係." 2015. http://repository.lib.cuhk.edu.hk/en/item/cuhk-1291673.

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Kwok, Wai Leung Anthony.
Thesis Ph.D. Chinese University of Hong Kong 2015.
Includes bibliographical references (leaves 127-143).
Abstracts also in Chinese; some appendixes in Chinese.
Title from PDF title page (viewed on 03, November, 2016).
Kwok, Wai Leung Anthony.
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KL, Yang, and 楊昆龍. "A Study of Lumbar Bone Mineral Density and Related Factors in a Taipei Local Hospital." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/63968406615886862348.

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碩士
高雄醫學院
醫學研究所
87
Objective: To study the relationship among bone mineral density and the related factors and obtain evidence to guide the prevention of osteoporosis. Method: Bone mineral density of lumbar spine in 254 healthy Taiwanese (91 men aged 21-81,mean 43.6 years; and 163 women aged 21-83, mean 46.7 years) were measured, and other markers ( including bone marker - alkaline phosphatase and lipid profile - triglyceride, cholesterol, HDL and LDL ) were measured as possible as we can. Result: (1) For adult male and female, the peak value of mean lumbar BMD in every decade occurred in those aged 21-30. In male, the lumbar BMD decreased slowly with age, but in female, which decreased markedly only after 50 years old. (2) In bivariate analysis of lumbar BMD, the female significant variables were age, body weight, body height and LDL/HDL ratio; and in female, the significant ones were age, body height and ALP. (3) In multiple linear regression of lumbar BMD, age, body weight, body height and LDL/HDL ratio were not significant variables in male, and age, body height and ALP were all significant in female. (4) The risk for osteoppenia or osteoporosis between both sexes and among different age groups was calculated using multiple logistic regression. The risk for osteopenia or osteoporosis among male was significantly greater than that among female ( OR=1.834; 95% CI, 1.000 to 3.362 ) after adjusting for age and BMI. The risk for osteopenia or osteoporosis among people aged 51-60 and >60 was significantly greater than that among people with age<51(OR=14.168; 95% CI, 5.125 to 39.167 and OR=15.045; 95% CI, 5.438 to 41.623 respectively) after adjusting for sex and BMI. And the risk for osteoporosis among people aged 51-60 and >60 was significantly greater than that among people with age<51(OR=21.249; 95% CI, 5.444 to 82.937 and OR=42.735; 95% CI, 11.404 to 160.143 respectively) after adjusting for sex and BMI. Conclusion: Sex and age were both significant predictors for bone loss, and which should be considered in the prevention of osteoporosis.
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Books on the topic "Lumbar Spine Bone Mineral Density"

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National Center for Health Statistics (U.S.) and National Health and Nutrition Examination Survey (U.S.), eds. Lumbar spine and proximal femur bone mineral density, bone mineral content, and bone area, United States, 2005-2008: Data from the National Health and Nutrition Examnination Survey (NHANES). Hyattsville, Md: U.S. Dept. of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2012.

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Elder, Grahame J. Metabolic bone disease after renal transplantation. Edited by Jeremy R. Chapman. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0288.

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Patients who undergo kidney transplantation have laboratory, bone, and soft tissue abnormalities that characterize chronic kidney disease mineral and bone disorder (CKD-MBD). After successful transplantation, abnormal values of parathyroid hormone, fibroblast growth factor 23, calcium, phosphate, vitamin D sterols, and sex hormones generally improve, but abnormalities often persist. Cardiovascular risk remains high and is influenced by prevalent vascular calcification, and fracture risk increases due to a combination of abnormal bone ‘quality’, compounded by immunosuppressive drugs and reductions in bone mineral density. Patients with well managed CKD-MBD before transplantation generally have a smoother post-transplant course, and it is useful to assess patients soon after transplantation for risk factors relevant to the general population and to patients with CKD. Targeted laboratory assessment, bone densitometry, and X-ray of the spine are useful for guiding therapy to minimize post-transplant effects of CKD-MBD. To reduce fracture risk, general measures include glucocorticoid dose minimization, attaining adequate 25(OH)D levels, and maintaining calcium and phosphate values in the normal range. Calcitriol or its analogues and antiresorptive agents such as bisphosphonates may protect bone from glucocorticoid effects and ongoing hyperparathyroidism, but the efficacy of these therapies to reduce fractures is unproven. Alternate therapies with fewer data include denosumab, strontium ranelate, teriparatide, oestrogen or testosterone hormone replacement therapy, tibolone, selective oestrogen receptor modulators, and cinacalcet. Parathyroidectomy may be necessary, but is generally avoided within the first post-transplant year. A schema is presented in this chapter that aims to minimize harm when allocating therapy.
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Wolman, Roger. Sports injuries in the pelvic region. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.007015.

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♦ The pelvis acts as a fulcrum for the forces transmitted between the lower limb and trunk especially on twisting and turning movements while running, and in the reverse direction when kicking. Sports injuries around the pelvis are therefore common in weight-bearing sports, such as running, football, rugby, and basketball♦ Injury can occur to the various structures around the pelvis. Bone stress injuries affect the symphysis pubis, pubic rami, femoral neck, and sacrum. Stress fractures are more common in women and may occur as part of the female athlete triad (Box 7.15.1) where there is hypo-oestrogenaemia and low bone density♦ Tendon injuries, including enthesopathies, most commonly affect the adductors, lower abdominals, glutei and hamstrings. Hip injuries can occur as a result of labral tears and femoroacetabular impingement. Sacroiliac joint instability may also cause symptoms especially in the buttock region. Synovitis of either joint may suggest an inflammatory arthritis♦ Pain is the most common symptom. However it may be referred from elsewhere, especially the lumbar spine. Pain may also originate from other systems including the reproductive organs and the gastrointestinal and urinary tracts.
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Book chapters on the topic "Lumbar Spine Bone Mineral Density"

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Yang, Yulong, and Shinya Ishii. "Serum Uric Acid and Biomarkers of Lumbar Spine Bone Mineral Density." In Biomarkers in Bone Disease, 201–20. Dordrecht: Springer Netherlands, 2017. http://dx.doi.org/10.1007/978-94-007-7693-7_1.

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Yang, Yulong, and Shinya Ishii. "Serum Uric Acid and Biomarkers of Lumbar Spine Bone Mineral Density." In Biomarkers in Bone Disease, 1–20. Dordrecht: Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-007-7745-3_1-1.

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Tanizawa, Tatsuhiko, Saburo Nishida, Noriaki Yamamoto, Shinobu Asai, and Hideaki E. Takahashi. "Changes of Bone Mineral Content of Lumbar Spine in Osteoporotic Patients Treated with Vitamin D and Calcitonin." In Spinal Disorders in Growth and Aging, 215–19. Tokyo: Springer Japan, 1995. http://dx.doi.org/10.1007/978-4-431-66939-5_20.

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Aronis, Konstantinos N., Elizabeth Sienkiewicz, Sharon H. Chou, Mary Brinkoetter, John P. Chamberland, Kalliopi M. Aramopatzi, Chuanyun Gao, Faidon Magos, and Christos S. Mantzoros. "Human Recombinant Leptin (Metreleptin) Administration for 2 Years Is an Effective Treatment for Hypothalamic Amenorrhea and Increases Bone Mineral Density at the Lumbar Spine: A Pilot Study." In BASIC/TRANSLATIONAL/CLINICAL - Late Breaking Research in Endocrinology, LB—3—LB—3. The Endocrine Society, 2011. http://dx.doi.org/10.1210/endo-meetings.2011.part1.or1.lb-3.

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"ALFACALCIDOL IN PREDNISONE TREATMENT:EFFECT ON BONE MINERAL CONTENT IN LUMBAR SPINE AND FEMUR." In Vitamin D, 838–39. De Gruyter, 1988. http://dx.doi.org/10.1515/9783110846713.838.

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Sutcliffe, Anne, and Cameron Swift. "Understanding Bone Conditions." In Adult Nursing Practice. Oxford University Press, 2012. http://dx.doi.org/10.1093/oso/9780199697410.003.0013.

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The aim of this chapter is to provide nurses with the knowledge to be able to assess, manage, and care for people with bone conditions in an evidence-based and person-centred way. Bone conditions (a major category of musculoskeletal conditions) cover a wide spectrum of diseases, some of which may be considered mild and self-limiting, while others may have a significant impact upon the individual’s quality of life and ability to function. It is estimated that up to 30% of all GP consultations are about musculoskeletal complaints; many are age-associated, and population ageing will continue to increase this demand (Oliver, 2009). The chapter will focus on osteoporosis, hip fracture (perhaps the most serious and costly consequence of osteoporosis or osteopaenia), Paget’s disease, and osteoarthritis, respectively. The chapter will provide a broad overview of these common conditions, enabling a proactive approach to patient care within a multidisciplinary context, whether in the primary or secondary care setting. The nursing management of the symptoms and common health problems associated with bone conditions can be found in several Part 2 chapters, and these are highlighted throughout the chapter. Osteoporosis has been defined as:...A progressive systemic skeletal disease characterised by low bone mass and micro-architectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. (WHO, 1994)…The World Health Organization (WHO) has recommended a clinical definition of osteoporosis based on a bone mineral density (BMD) measurement of the spine or hip, expressed in standard deviation (SD) units called T scores. Using this definition, an individual is classified as having osteoporosis if his or her T score is ≤–2.5 SD at the spine or hip (WHO, 1994). It is estimated that osteoporosis occurs in approximately 3 million people in the UK, resulting in more than 230,000 fractures per annum, the most frequent being hip, vertebral body, and forearm fractures. In total, 75,000 hip fractures occur annually (British Orthopaedic Association, 2007), with the average age of incidence being 84 and 83 in men and women, respectively (National Hip Fracture Database, 2010).
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Kankam, Sarafina, Gregory Lawson Smith, and Johnathan Goree. "Patient selection." In Sacroiliac Joint Pain, edited by Alaa Abd-Elsayed and Dawood Sayed, 169–76. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780197607947.003.0016.

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Sacroiliac joint fusion has become a mainstay of the treatment of low back pain for both surgeons and interventionalists. This chapter discusses proper patient selection for both open and minimally invasive sacroiliac joint fusion techniques. Topics covered are indications and contraindications for surgery as well as imaging modalities that the provider can use to ascertain the integrity of the sacroiliac joint when fusion is being considered. It is important to assess each patient’s psychiatric history and current psychiatric symptoms, weigh the benefits and the risks of the procedure, and then use clinical judgment before proceeding with surgery. A brief overview of the two most common surgical approaches (lateral and posterior), along with survivorship data, is provided. Other patient considerations include bone density, previous lumbar spine surgery, smoking history, and comorbidities such as diabetes mellitus.
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Conference papers on the topic "Lumbar Spine Bone Mineral Density"

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Ma, H. T., Haiyan Lv, J. F. Griffith, Alvin F. W. Li, David K. W. Yeung, J. Leung, Ping-Chung Leung, and Jing Yuan. "Perfusion and bone mineral density as function of vertebral level at lumbar spine." In 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6346717.

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Chu, Bryant, Jeremi Leasure, and Dimitriy Kondrashov. "Selective Densitometry of the Lumbar Spine." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14218.

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Bone mineral density (BMD) has been identified as a major factor in spine construct strength, with failures resulting in pedicle screw loosening and pullout2. Computed tomography (CT) scans have been shown to effectively measure BMD1,4. Previous research has utilized this linear correlation of CT Hounsfield Units (HU) to BMD in order to determine BMD as a function of anatomic location within cervical vertebrae1; however, the lumbar spine has not yet been reported on. The goal of this study was to describe BMD of anatomical regions within lumbar vertebrae using the correlation between HU and BMD. It was hypothesized that posterior elements of the spine would exhibit significantly different BMD than the vertebral body. This was tested through means comparison of BMD for each anatomical region.
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Ting Ma, Heather, James F. Griffith, Zhengyi Yang, Anthony Wai Leung Kwok, Ping Chung Leung, and Raymond Y. W. Lee. "Study on the kinematic pattern of lumbar spine in subjects with varied bone mineral density." In 2008 International Conference on Technology and Applications in Biomedicine (ITAB). IEEE, 2008. http://dx.doi.org/10.1109/itab.2008.4570631.

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Yoganandan, Narayan, Frank A. Pintar, Recai Aktay, Glenn Paskoff, and Barry S. Shender. "Bone Mineral Density of Cervical Spine Vertebrae Using Quantitative Computed Tomography." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-59726.

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While numerous studies exist quantifying the bone mineral content of the human lumber vertebrae, such information is not available for the cervical spine. This study determined the bone mineral densities of cervical vertebrae. Adult healthy human volunteers, ages ranging from 18 to 40 years, underwent quantitative computed tomography scanning of the neck. BMD data were divided according to subject weight (above and below 50th percentile, termed low and heavy mass) and gender. Low-mass subjects did not consistently have higher bone mineral density at all levels of the cervical column. Bone mineral were higher (259 ± 6 mg/cc) for females than males (247 ± 8 mg/cc); for the entire ensemble the mean density was 253 ± 9 mg/cc. Altered strength of cervical vertebrae coupled with the increased mobility of the disc at the inferior levels of the neck may explain regional biomechanical differences and subsequent physiologic effects secondary to aging. This study quantifies BMD of the human neck vertebrae and offers explanations to the biomechanical behaviors of the human cervical spine.
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Konig, A., N. Keough, and F. Joseph. "Bone mineral density of the lumbar spine in a South African population using Computed Tomography scans." In 2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC). IEEE, 2018. http://dx.doi.org/10.1109/saibmec.2018.8363173.

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Liddle, Kate D., Michael A. Tufaga, Glenn Diekmann, Jenni M. Buckley, Viva Tai, Kathleen Mulligan, Christopher Ames, and Robert T. McClellan. "Assessment of Cancellous Bone Strength in the Lumbar Spine Using a “Smart” Ball-Tip Probe." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19121.

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Failure of the pedicle screw at the screw-bone interface is a common clinical problem, particularly in the setting of osteoporosis, and poses reconstructive challenges for all orthopaedic surgeons. Pedicle screw failure through screw loosing and pull-out is highly correlated with bone mineral density (BMD) and local bone quality [1]. Pre-operative assessment of BMD via dual x-ray absorptiometry (DEXA) has been shown to help determine the need for screw augmentation. However, patients frequently present without pre-operative DEXA scans. Furthermore, DEXA scans provide a measure of general bone quality, but do not necessarily reflect segmental and local variation in the spine [2]. The ability to assess BMD on a per-vertebrae basis intra-operatively would assist with surgical decisions regarding screw sizing, placement and augmentation.
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Emili, I., S. Faenza, S. Gitto, D. Albano, C. Messina, and L. M. M. Sconfienza. "Comparison of Lumbar Spine Bone Mineral Density Values by Dual-Energy X-Ray Absorptiometry with Quantitative Computed Tomography: Preliminary Results." In ESSR 2020 Virtual Meeting. Thieme Medical Publishers, Inc., 2020. http://dx.doi.org/10.1055/s-0040-1722495.

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Dias, Aline de Fátima, Lucas Scárdua Silva, Rafael Batista João, Amanda Canal Rigotti, Gabriel Ferri Baltazar, Ricardo Brioschi, Marina Koutsodontis Machado Alvim, Marcia Elisabete Morita Shermann, Fernando Cendes, and Clarissa Lin Yasuda. "Enzyme-inducing antiseizure drugs associate with low bone mineral density in men with epilepsy." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.155.

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Introduction: Little is known about the impact of enzyme-inducing antiseizure drugs (EI-ASD) on the reduction of Bone Mineral Density (BMD) in men with epilepsy (MWE). Objectives: To evaluate the BMD in MWE exposed to EI-ASDs (phenytoin, carbamazepine and phenobarbital) and its relationship with the duration of epilepsy. Methods: We evaluated BMD from 74 consecutive MWE (median age (range), 52.5 (25- 74) years) exposed to previous or current EI-ASDs, followed at UNICAMP-Brazil. Individuals were split into two groups (young-group, 31 individuals [25-49 years]; older group, 43 subjects, [50-74 years]). The BMD test evaluated t-score indexes from the femoral neck, whole femur and lumbar spine. Osteopenia was defined with t-score of - 1.0 to -2.4; osteoporosis, with T-scores lower than -2.5. Data were extracted from medical records. We analyzed data with SPSS22, performed chi-square tests for categorical variables and applied a partial correlation test (controlled for age) between BD scores and duration of epilepsy. Results: BMD was reduced in 49/74 men (66.2%). Both groups presented equivalent proportions of BMD abnormalities (p=0.087) (young-group [14/41 normal (45%), 12/31 osteopenia (39%), 5/31 osteoporosis (16%)]; older-group [11/43 normal (26%), 16/43 osteopenia (37%), 16/43 osteoporosis (37%)]. BMD did not correlate with the duration of disease or age of onset. Conclusion: BMD reduction is highly prevalent in MWE exposed to EI-ASD, including young individuals. Data suggest that exposure to EI-ASD may associate with early BMD reduction, which evolve to osteopenia and osteoporosis. BMD evaluation in MWE and appropriate treatment may be necessary to reduce fractures’ risk.
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Wang, Yu, and Zhuoli Zhang. "AB0356 COMPARISION FOREARM BONE MINERAL DENSITY BETWEEN LUMBAR SPINE AND HIP: A USEFUL TOOL TO SCREEN OSTEOPOROSIS IN FEMALE PATIENTS WITH RHEUMATOID ARTHRITIS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.631.

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Keywani, K., H. G. Raterman, M. M. ter Wee, M. T. Nurmohamed, A. E. Voskuyl, I. E. Bultink, and W. F. Lems. "SAT0143 The arrest of bone mineral density loss at the lumbar spine and hip in patients with active rheumatoid arthritis during rituximab therapy." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.4827.

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