Relevant bibliographies by topics / Lschaemia with no obstructive coronary artery disease

Academic literature on the topic 'Lschaemia with no obstructive coronary artery disease'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Lschaemia with no obstructive coronary artery disease"

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Kereiakes, Dean J. "Chronic Obstructive Coronary Artery Disease." Reviews in Cardiovascular Medicine 10, S2 (February 20, 2009): 1–2. http://dx.doi.org/10.3909/ricm10s20001.

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Sechtem, Udo, David Brown, Shigeo Godo, Gaetano Antonio Lanza, Hiro Shimokawa, and Novalia Sidik. "Coronary microvascular dysfunction in stable ischaemic heart disease (non-obstructive coronary artery disease and obstructive coronary artery disease)." Cardiovascular Research 116, no. 4 (February 8, 2020): 771–86. http://dx.doi.org/10.1093/cvr/cvaa005.

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Abstract Diffuse and focal epicardial coronary disease and coronary microvascular abnormalities may exist side-by-side. Identifying the contributions of each of these three players in the coronary circulation is a difficult task. Yet identifying coronary microvascular dysfunction (CMD) as an additional player in patients with coronary artery disease (CAD) may provide explanations of why symptoms may persist frequently following and why global coronary flow reserve may be more prognostically important than fractional flow reserve measured in a single vessel before percutaneous coronary intervention. This review focuses on the challenges of identifying the presence of CMD in the context of diffuse non-obstructive CAD and obstructive CAD. Furthermore, it is going to discuss the pathophysiology in this complex situation, examine the clinical context in which the interaction of the three components of disease takes place and finally look at non-invasive diagnostic methods relevant for addressing this question.
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Dharampal, A. S., and P. J. de Feyter. "Coronary artery calcification: does it predict obstructive coronary artery disease?" Netherlands Heart Journal 21, no. 7-8 (July 2013): 344–46. http://dx.doi.org/10.1007/s12471-013-0436-5.

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Verghese, D., V. Manabolu, L. Alalawi, J. Aldana-Bitar, A. Kinninger, and M. Budoff. "505 Coronary Calcium And Obstructive Coronary Artery Disease." Journal of Cardiovascular Computed Tomography 16, no. 4 (July 2022): S49. http://dx.doi.org/10.1016/j.jcct.2022.06.116.

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Mandal, Swapna, and Brian D. Kent. "Obstructive sleep apnoea and coronary artery disease." Journal of Thoracic Disease 10, S34 (December 2018): S4212—S4220. http://dx.doi.org/10.21037/jtd.2018.12.75.

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Reynolds, Harmony R. "Myocardial infarction without obstructive coronary artery disease." Current Opinion in Cardiology 27, no. 6 (November 2012): 655–60. http://dx.doi.org/10.1097/hco.0b013e3283583247.

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Jyotsna, Maddury, Madhavapeddy Aditya, and Nemani Lalitha. "Obstructive Coronary Artery Disease in Young Females." Indian Journal of Cardiovascular Disease in Women WINCARS 01, no. 01 (March 2016): 004–7. http://dx.doi.org/10.1055/s-0038-1656468.

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AbstractBACKGROUND: To define myocardial infarction in “young”, many studies taken < 40 to 45 yrs. of age as cut off point. We have data in young males with obstructive coronary artery disease, but limited data in young females.OBJECTIVES: To see the disease pattern, risk factors, presentation, ventricular function and PCI efficiency of young females in comparison with young males with obstructive coronary artery disease who require PCI.MATERIAL AND METHODS We retrospectively analyzed the data of young patients (< 45 yrs. of age) who undergone PCI over past two years. We noted the clinical, investigative and treatment modalities of these patients.RESULTS: 200 young patients had undergone PCI for obstructive CAD with 42 females over two year period. Females had more frequently hypertension (69.1% vs. 43.7%) and Type 2 Diabetes (33.3% vs22.8%) which are statistically significant. Smoking was frequent in young males than young females. Males were presented as acute MI, whereas females with rest chest pain. Multi-vessel involvements, LV dysfunction, success of PCI and complication rates were similar in both groups. Females are more anemic (< 11 g/dl in females and < 13g/dl in males). Complexity of lesion (B2 or C type of lesions) is more in females which is statistically significant.CONCLUSION: Young females had more frequently hypertension, Diabetes, acute coronary syndrome without MI, mild anemia, complex lesions than young males, but with same success and complication rate of PCI.
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Lüthje, Lars, and Stefan Andreas. "Obstructive sleep apnea and coronary artery disease." Sleep Medicine Reviews 12, no. 1 (February 2008): 19–31. http://dx.doi.org/10.1016/j.smrv.2007.08.002.

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Hedner, Jan, Karl A. Franklin, and Yüksel Peker. "Obstructive Sleep Apnea and Coronary Artery Disease." Sleep Medicine Clinics 2, no. 4 (December 2007): 559–64. http://dx.doi.org/10.1016/j.jsmc.2007.07.008.

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Jyotsna, Maddury, and Madhavapeddy Aditya. "Obstructive Coronary Artery Disease in Young Females." American Journal of Cardiology 111, no. 7 (April 2013): 81B. http://dx.doi.org/10.1016/j.amjcard.2013.01.205.

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Dissertations / Theses on the topic "Lschaemia with no obstructive coronary artery disease"

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Alshahrani, Ali. "Derivation and Validation of a Clinical Tool to Predict Obstructive Coronary Artery Disease Among Patients with Zero Coronary Calcium Score." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38152.

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Coronary artery disease (CAD) is associated with significant morbidity and mortality. Coronary artery calcification (CAC) indicates presence of CAD. Absence of CAC is associated with very low risk of having CAD but not equal to zero. In this study, we aim at developing a clinical prediction tool to predict presence of obstructive CAD among patients with zero calcium score. We developed two models. A full prespecified model with 7 variables based on input from clinical experts, and a reduced model with 4 variables based on univariate screening. Both models showed an acceptable performance (c-statistics of 0.68 for both). Both models performed well when validated, externally for the full model and internally for the reduced one. We derived a clinical risk score of 20 points from the full model. We found that a score threshold of ≥ 14 is associated with presence of obstructive CAD with positive likelihood ratio of 5.5.
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Nisar, Shiraz A., Raghunandan Muppidi, Sumit Duggal, Adrian V. Hernández, Vidyasagar Kalahasti, Wael Jaber, and Omar A. Minai. "Impaired Functional Capacity Predicts Mortality in Patients with Obstructive Sleep Apnea." The American Thoracic Society, 2014. http://hdl.handle.net/10757/337271.

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oam1998@outlook.com
Background: Obstructive sleep apnea (OSA) is associated with increased mortality, for which impaired functional capacity (IFC) has been established as a surrogate. We sought to assess whether IFC is associated with increased mortality in patients with OSA and whether IFC is predictive of increased mortality after accounting for coronary artery disease. Methods: Patients with OSA who underwent both polysomnography testing and exercise stress echocardiogram were selected. Records were reviewed retrospectively for demographics, comorbidities, stress echocardiographic parameters, and polysomnography data. Univariable and multivariable logistic regression analysis was used to evaluate the association between IFC and overall mortality. We then evaluated the variables associated with IFC in the overall population and in the subgroup with normal Duke treadmill score (DTS). Results: In our cohort, 404 (26%) patients had IFC. The best predictors of IFC were female sex, history of smoking, ejection fraction less than 55, increased body mass index, presence of comorbidities, abnormal exercise echocardiogram, abnormal heart rate recovery, and abnormal DTS. Compared with those without IFC, patients with IFC were 5.1 times more likely to die (odds ratio [OR], 5.1; 95% confidence interval [CI], 2.5–10.5; P , 0.0001) by univariate analysis and 2.7 times more likely to die (OR, 2.7; 95% CI, 1.2–6.1; P = 0.02) by multivariate analysis, when accounting for heart rate recovery, DTS, and sleep apnea severity. Among those without coronary artery disease, patients with IFC were at significantly increased risk of mortality (OR, 4.3; 95% CI, 1.35–13.79; P = 0.0088) compared with those with preserved functional capacity. Conclusions: In our OSA population, IFC was a strong predictor of increased mortality. Among those with normal DTS, IFC identified a cohort at increased risk of mortality.
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Діденко, Д. В. "Коморбідність: у фокусі ішемічна хвороба серця та хронічне обструктивне захворювання легень." Thesis, Сумський державний університет, 2015. http://essuir.sumdu.edu.ua/handle/123456789/42048.

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Ішемічна хвороба серця (ІХС) та хронічне обструктивне захворювання легень (ХОЗЛ) мають спільні ланки патогенезу та взаємообтяжуючий вплив, що значно утруднює курацію хворих за умов їх поєднаного перебігу.
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Accarini, Renata. "Doença periodontal como fator de risco coronariano São José do Rio Preto: Faculdade de Medicina de São José do Rio Preto, 2006." Faculdade de Medicina de São José do Rio Preto, 2006. http://bdtd.famerp.br/handle/tede/243.

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Made available in DSpace on 2016-01-26T12:51:55Z (GMT). No. of bitstreams: 1 renataaccarini_dissert.pdf: 311540 bytes, checksum: 6e73d654b99ae5ef0d517cb9c91c09bb (MD5) Previous issue date: 2006-10-16
Ainda permanecem controvérsias quanto à ligação causal e mecanismos fisiopatológicos que expliquem a associação entre Doença Periodontal e Doenças Cardiovasculares. Objetivo: Detectar a existência de associação entre doença periodontal ativa (DP) e ocorrência de Síndromes Coronárias Agudas (SCA). Casuística e Método: Foram avaliados 361 pacientes (57,3% do sexo masculino), com idades variando de 27 a 89 (médiaDP=60,512,2 anos) internados na Unidade de Tratamento Intensivo de um Hospital de Ensino com quadro clínico e complementar de SCA. Todos foram submetidos a exame periodontal completo, no próprio ambiente da UTI sendo que 325 (90,0%) realizaram cinecoronariografia para confirmação diagnóstica e/ou programação de conduta terapêutica. O exame periodontal consistiu na avaliação de todos os dentes presentes na cavidade oral e dos seguintes parâmetros: profundidade clínica de sondagem, nível de inserção clinica, índice de placa e índice gengival. Resultados: Dos 325 pacientes, 91 (28,0%) apresentavam artérias coronárias isentas de obstrução ou com obstruções discretas (<= 50% de perda de diâmetro), havendo obstruções importantes nos 72,0% restantes. O teste exato de Fisher mostrou valor de P de 0,0245 e ODDS Ratio de 2,571 (IC 95% 1,192 a 5,547), ou seja, documentou-se cerca de 2,5 vezes mais possibilidade de presença de DP ativa no grupo com SCA e coronariopatia obstrutiva significante. Conclusão: Constatou-se associação significante entre presença de doença periodontal ativa e doença coronária obstrutiva de grau importante em pacientes com Síndrome Coronária Aguda, reforçando a importância da prevenção e tratamento adequado da doença periodontal, que deve ser considerada como fator de risco potencial na etiologia e na instabilização da placa aterosclerótica. Abstract Positive association between periodontal disease and coronary diseases is unclear concerning physiopathologic mechanisms and causal relationship. The aim of this study was to assess the association between active periodontal disease active and obstructive coronary artery disease in patients with acute coronary syndromes. Method: 361 (57.3% males; mean age 60.5+12.2) patients referred for diagnostic coronary vessel disease were assessed for periodontal disease and also submitted to coronary angiography with diagnostic and prognostic purposes. Each patient underwent a full-mouth periodontal examination which included gingival bleeding, plaque index, periodontal pocket depths, attachment levels and missing teeth. For statistical analysis was used the Exact Fisher test and was accepted an Alfa error of 5%. Results: 28% patients haven t significant coronary vessel obstructions (<50% diameter obstruction) and 72.0% had significant obstructive disease (>50% diameter obstruction). The Exact Fisher Test showed p-value of 0.0245 and ODDS Ratio of 2.571 (95%CI from 1.192 to 5.547). So there was a 2.5 fold increase in the chance for active periodontal disease in patients with significant obstructive coronary artery disease. Conclusion: Our study indicates a positive and significant association between periodontal disease and obstructive coronary disease among patients with acute coronary syndromes becoming periodontal disease as a potential risk factor in etiology and outcome of atherosclerotic plaque. Results of this and other investigations should be taken into account in the future researches in order to validate this association.
Ainda permanecem controvérsias quanto à ligação causal e mecanismos fisiopatológicos que expliquem a associação entre Doença Periodontal e Doenças Cardiovasculares. Objetivo: Detectar a existência de associação entre doença periodontal ativa (DP) e ocorrência de Síndromes Coronárias Agudas (SCA). Casuística e Método: Foram avaliados 361 pacientes (57,3% do sexo masculino), com idades variando de 27 a 89 (média DP=60,5 12,2 anos) internados na Unidade de Tratamento Intensivo de um Hospital de Ensino com quadro clínico e complementar de SCA. Todos foram submetidos a exame periodontal completo, no próprio ambiente da UTI sendo que 325 (90,0%) realizaram cinecoronariografia para confirmação diagnóstica e/ou programação de conduta terapêutica. O exame periodontal consistiu na avaliação de todos os dentes presentes na cavidade oral e dos seguintes parâmetros: profundidade clínica de sondagem, nível de inserção clinica, índice de placa e índice gengival. Resultados: Dos 325 pacientes, 91 (28,0%) apresentavam artérias coronárias isentas de obstrução ou com obstruções discretas (<= 50% de perda de diâmetro), havendo obstruções importantes nos 72,0% restantes. O teste exato de Fisher mostrou valor de P de 0,0245 e ODDS Ratio de 2,571 (IC 95% 1,192 a 5,547), ou seja, documentou-se cerca de 2,5 vezes mais possibilidade de presença de DP ativa no grupo com SCA e coronariopatia obstrutiva significante. Conclusão: Constatou-se associação significante entre presença de doença periodontal ativa e doença coronária obstrutiva de grau importante em pacientes com Síndrome Coronária Aguda, reforçando a importância da prevenção e tratamento adequado da doença periodontal, que deve ser considerada como fator de risco potencial na etiologia e na instabilização da placa aterosclerótica.
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Погорєлова, Оксана Сергіївна, Оксана Сергеевна Погорелова, Oksana Serhiivna Pohorielova, and К. М. Малиш. "Дослідження механічних властивостей артерій у хворих на хронічне обструктивне захворювання легень у поєднанні із хронічною ішемічною хворобою серця." Thesis, Сумський державний університет, 2014. http://essuir.sumdu.edu.ua/handle/123456789/35728.

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Хронічне обструктивне захворювання легень (ХОЗЛ) є однією з провідних причин захворюваності і смертності в сучасному суспільстві і являє собою значну соціальну та економічну проблему, яка поки що не має тенденції до покращення. За даними ряду досліджень, розповсюдженість ХОЗЛ у світі у людей старших за 40 років складає 10,1 % (11,8 % у чоловіків і 8,5 % у жінок). Згідно даних популяційних досліджень, у хворих на ХОЗЛ ризик серцево-судинної смерті вищій у 2–3 рази і складає приблизно 50 % від загальної кількості смертельних випадків. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/35728
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Ferreira, Maria Angelica Pires. "Escore de cálcio coronariano, índice tornozelobraquial e proteína C reativa em tabagistas pesados com doença pulmonar obstrutiva crônica e com espirometria normal." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/99172.

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INTRODUÇÃO. Estudos de qualidade variável mostram maior prevalência de doença cardiovascular e de marcadores de aterosclerose em tabagistas com doença pulmonar obstrutiva crônica (DPOC) em relação a tabagistas sem a doença. OBJETIVOS. Verificar se escore de cálcio coronariano (ECC) elevado e anormalidade do índice tornozelo-braquial (ITB) são mais prevalentes em tabagistas pesados com DPOC do que sem DPOC, e se proteína C reativa sérica (PCR) e volume expiratório forçado no primeiro segundo em relação ao previsto (VEF1%) se correlacionam com ECC e ITB em tabagistas com e sem DPOC. POPULAÇÃO E MÉTODOS. Foram incluídos indivíduos consecutivos com carga tabágica @ 20 maços-ano. Os pacientes foram divididos em grupo 1 (com DPOC) e grupo 2 (assintomáticos respiratorios com espirometria normal). Coletaram-se dados clínicos, laboratoriais e antropométricos e determinados ECC, ITB e PCR sérica. Comparouse a prevalência de ECC acima do percentil 75 e de ITB anormal entre os grupos, e verificou-se a correlação entre PCR, ECC e ITB e entre VEF1%, ECC e ITB.
BACKGROUND. Studies of various quality levels show higher prevalence of cardiovascular disease and atherosclerosis markers in smokers with chronic obstructive pulmonary disease (COPD) compared to smokers without the disease. OBJECTIVES. The aims of this study were, firstly, to verify whether an elevated coronary calcium score (CCS) and abnormal ankle-brachial index (ABI) are more prevalent in heavy smokers with COPD than in those without COPD, and secondly, to investigate whether serum C-reactive protein (CRP) and predicted forced expiratory volume in the first second (FEV1%) are correlated with CCS and ABI in smokers with and without COPD. METHODS. We included clinically stable consecutive individuals with smoking history of @ 20 pack-years and COPD (group 1) or normal spirometry (group 2). Clinical, laboratory and anthropometric data were collected and CCS, ABI and serum CRP were measured. We compared the prevalence of CCS above the 75th percentile and the rates of abnormal ABI in both groups. Additionally, the correlation between CRP, CCS and ABI and FEV1%, CCS, and ABI was determined.
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Soares, Flavia de Souza Nunes. "A prevalência e impacto da síndrome da apneia obstrutiva do sono em pacientes submetidos à cirurgia de revascularização miocárdica." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-04112010-140956/.

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Introdução: A apneia obstrutiva do sono (AOS) é caracterizada por episódios recorrentes de colapso parcial ou completo da faringe responsáveis por roncos e eventos de hipopneia ou apneia, respectivamente, associados à queda de saturação de oxigênio e despertares frequentes durante o sono. A AOS está associada à doença arterial coronariana e é um fator de risco independente para complicações após cirurgia. Entretanto, a maioria dos pacientes com AOS submetidos à cirurgia não tem suspeita ou diagnóstico prévio de AOS. Objetivos: O principal objetivo do estudo foi determinar prevalência da AOS em candidatos à cirurgia de revascularização do miocárdio (RM) e compará-la à prevalência da AOS em candidatos à cirurgia abdominal eletiva (ABD-cirurgia). Como objetivo secundário, avaliamos os preditores clínicos e o desempenho do questionário de Berlin, que estratifica os pacientes em alto risco e baixo risco de AOS, como teste de triagem no pré-operatório, assim como os preditores clínicos de AOS em ambos os grupos. Métodos: Foram incluídos 40 pacientes consecutivos no grupo RM [29 homens; idade: 56±7 anos; índice de massa corporal (IMC): 30±4 kg/m2], e 41 pacientes no grupo ABD-cirurgia, que foram pareados para sexo, idade e IMC (28 homens; idade: 56±8 anos; IMC: 29±5 11 kg/m2). Todos os pacientes foram submetidos à polissonografia completa noturna (PSG) e à avaliação clínica e laboratorial pré-operatória, incluindo avaliação da sonolência diurna com a escala de sonolência Epworth (ESS) e com o questionário de Berlin. Resultados: A prevalência de AOS (índice de apneia hipopneia na PSG 15 eventos/hora) no grupo RM e ABD-cirurgia foi alta e semelhante (52% e 41%, respectivamente, p=0,32). O grupo RM apresentou menor nível de sonolência (ESS: 6±3 e 9±5; RM vs. ABD-cirurgia, respectivamente, p=0,008). A sensibilidade e a especificidade do Berlin no grupo RM foi 67% e 26%, e no grupo ABD-cirurgia, 82 e 62%, respectivamente. O IMC, as circunferências abdominal e cervical, a pressão arterial sistólica, a pressão arterial diastólica, os triglicerídeos, a lipoproteína de alta densidade sérica (HDL-c), a Diabetes Mellitus e o risco alto de AOS (de acordo com questionário de Berlin) se correlacionaram com a AOS na análise univariada. No entanto, a circunferência abdominal foi o único preditor independente associado à presença de AOS após regressão logística múltipla. Conclusão: A AOS é extremamente comum entre pacientes candidatos à cirurgia cardíaca e cirurgia abdominal. O questionário de Berlin apresentou baixa sensibilidade para detecção AOS em pacientes do grupo RM, mas a sensibilidade e a especificidade no grupo ABD-cirurgia foram semelhantes aos valores encontrados na literatura. A sonolência diurna não está associada à presença de AOS entre portadores de doença arterial coronariana com indicação de tratamento cirúrgico e entre candidatos à cirurgia abdominal eletiva, o que pode ajudar a explicar o subdiagnóstico de AOS na nossa população
Background: The obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial or complete collapse of the pharynx account for snoring and apnea or hypopnea events, respectively, associated with the decrease of oxygen saturation and frequent arousals during sleep. OSA is associated with coronary artery disease and is an independent risk factor for complications after surgery. However, most patients with OSA undergoing surgery is not suspected or previously diagnosed OSA. Objectives: The main objective of this study was to determine the prevalence of OSA in candidates for coronary arterial bypass grafting surgery (CABG) and compare it with the prevalence of OSA in candidates for elective abdominal surgery (ABD-surgery). As a secondary objective, we evaluated the clinical predictors and performance of the Berlin questionnaire, which stratifies patients into high risk and low risk for OSA, as a screening test in the preoperative as well as clinical predictors of OSA in both groups. Methods: We included 40 consecutive patients in the CABG group [29 men, age: 56 ± 7 years, body mass index (BMI): 30 ± 4 kg/m2] and 41 patients in the ABD-surgery, who were matched for gender, age and BMI (28 men, age: 56 ± 8 years, BMI: 29 ± 5 kg/m2 ¬). All patients underwent full nocturnal polysomnography (PSG) and clinical and laboratory pre-operative evaluation, 14 including assessment of daytime sleepiness with the Epworth Sleepiness Scale (ESS) and the Berlin questionnaire. Results: The prevalence of OSA (apnea hypopnea index in PSG 15 events/hour) in the RM group and ABD-surgery was high and similar (52% and 41% respectively, p = 0.32). Patients submitted to CABG presented lower levels of daytime somnolence than ABD-surgery patients (ESS: 6±3 vs. 9±5; p=0.008, respectively). The sensitivity and specificity of Berlin in the RM group was 67% and 26%, and ABD-surgery group, 82 and 62% respectively. The BMI, waist and neck circumference, systolic blood pressure, diastolic blood pressure, triglycerides, serum high density lipoprotein (HDL-C), Diabetes Mellitus and the high risk of OSA (according to questionnaire Berlin) correlated with OSA in univariate analysis. However, waist circumference was the only independent predictor associated with the presence of OSA after multiple logistic regression. Conclusion: OSA is extremely common among patients who are candidates for CABG and abdominal surgery. The Berlin questionnaire showed low sensitivity for detecting OSA in patients in the RM group, but the sensitivity and specificity in ABD-surgery group were similar to those found in the literature. Daytime sleepiness is not associated with the presence of OSA among patients with coronary artery disease with indication for surgical treatment and patients with indication for elective abdominal surgery, which may help explain the underdiagnosis of OSA in our population
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Mota, Igor Larchert. "Lesões coronárias em pacientes com doença pulmonar obstrutiva crônica (GOLD I a III) e doença arterial coronária suspeita ou confirmada." Pós-Graduação em Ciências da Saúde, 2018. http://ri.ufs.br/jspui/handle/riufs/7641.

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Fundação de Apoio a Pesquisa e à Inovação Tecnológica do Estado de Sergipe - FAPITEC/SE
BACKGROUND: Systemic inflammation is the pathophysiological link between coronary artery disease (CAD) and chronic obstructive pulmonary disease (COPD). However, the influence of underdiagnosed COPD on patients with suspected or diagnosed CAD is unknown. Therefore, the objective was to evaluate the degree of coronary involvement in COPD patients with suspected or confirmed CAD. Methods: For this cross-sectional study which we carried out March 2015 and June 2017, 210 outpatients with suspected or confirmed CAD were concomitantly underwent spirometry and coronary angiography or multidetector computed tomography. Two groups were defined: with and without COPD. Size, site, extent, and calcification of the coronary lesions, and the severity of COPD were analyzed. Results: COPD patients (n=101) presented: higher frequency of obstructive coronary lesions ≥ 50% 72 (71.3%), multi-vessels 29 (28.7%), of the left main 18 (17.8%), atherosclerotic plaques more calcified and higher Agatston coronary calcium score than the patients without COPD (p < 0.0001). The greater COPD in the GOLD stages, the more severe the CAD and the more calcified the coronary plaques (p < 0.0001). However, there was no difference between the two groups with respect to the main risk factors for CAD. In the univariate analysis, the COPD and the male gender have been risk predictors for CAD. In the multivariate analysis adjusted to COPD was independent predictor of obstructive CAD (odds ratio 4.78; CI 95% 2.21-10.34; p < 0.001). Conclusion: In patients with suspected or diagnosed CAD, the COPD was associated with a higher severity and extent of coronary lesions, calcific plaques, and elevated calcium score independently of the established risk factors for CAD. In addition, the more severe the COPD, the greater the severity of coronary lesions and calcification.
INTRODUÇÃO: A inflamação sistêmica constitui o elo fisiopatológico entre a doença arterial coronariana (DAC) e a doença pulmonar obstrutiva crônica (DPOC). Todavia a influência da DPOC não diagnosticada em pacientes com DAC suspeita ou diagnosticada é desconhecida. Portanto, objetivou-se avaliar o grau de acometimento coronariano em portadores de DPOC com DAC suspeita ou confirmada. MÉTODOS: Estudo transversal realizado entre março de 2015 a junho de 2017 com 210 pacientes ambulatoriais, com DAC suspeita ou confirmada, submetidos, ao concomitantemente, à espirometria e à cineangiocoronariografia ou à angiotomografia computadorizada das coronárias. A partir dos resultados definiram-se os grupos: com e sem DPOC. Foram analisadas tamanho, local, extensão e calcificação da lesão coronária, e gravidade da DPOC. RESULTADOS: O grupo com DPOC, com 101 (48%) voluntários, apresentou, comparativamente ao sem DPOC: maior frequência de DAC (88,1% vs 45%); de lesões obstrutivas ≥ 50% (71,3% vs 21,1%); de lesões multiarteriais (28,7% vs 8,3%); maior percentual de lesões de tronco da coronária esquerda (17,8% vs 3,7%); mais lesões graves (61,4% vs 10,1%); placas ateroscleróticas mais calcificadas e escore de cálcio mais elevado (p<0,0001). Quanto mais grave o estágio da DPOC (GOLD), mais grave a DAC e mais calcificadas as placas coronárias (p<0,0001). Entretanto, não houve diferenças entre os grupos quanto aos principais fatores de risco para DAC. Na análise univariada, a DPOC e o gênero masculino foram preditores de risco para DAC. Na análise multivariada ajustada apenas a DPOC foi preditora de DAC obstrutiva (odds ratio 4,78; IC95% 2,21-10,34; p<0,001). CONCLUSÃO: Em pacientes com DAC suspeita ou confirmada, a DPOC foi associada a maior gravidade e extensão das lesões coronárias, placas calcificadas e escore de cálcio elevados, independente, dos fatores de risco para DAC já estabelecidos. Além disso, quanto mais grave a DPOC maior a gravidade das lesões e calcificação coronárias.
Aracaju
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Винниченко, Людмила Боголюбівна, Людмила Боголюбовна Винниченко, Liudmyla Boholiubivna Vynnychenko, and Т. М. Головко. "Особливості лікування хронічної серцевої недостатності на тлі ішемічної хвороби серця в поєднанні з хронічним обструктивним захворюванням легень." Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/32816.

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Хронічна серцева недостатність (ХСН) на тлі ішемічної хвороби серця (ІХС) та хронічне обструктивне захворювання легень (ХОЗЛ) — найбільш поширені захворювання населення розвинених країн і складають більше 50% в структурі смертності. На теперішній час для лікування ХСН всіх функціональних класів в якості базисної терапії використовують бета-адреноблокатори (бета-АБ). При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/32816
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Винниченко, Людмила Боголюбівна, Людмила Боголюбовна Винниченко, Liudmyla Boholiubivna Vynnychenko, and Т. М. Головко. "Особливості перебігу хронічної серцевої недостатності на тлі ішемічної хвороби серця в поєднанні з хронічним обструктивним захворюванням легень." Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/32805.

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Хронічне обструктивне захворювання легень (ХОЗЛ) поєднане із хронічною серцевою недостатністю (ХСН) на тлі ішемічної хвороби серця (ІХС) займає домінуюче місце серед хвороб внутрішніх органів. Частота такого поєднання коливається в межах від 7% до 52%. Поєднання обох захворювань обтяжує їх перебіг та підвищує ймовірність смертельних наслідків. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/32805
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Books on the topic "Lschaemia with no obstructive coronary artery disease"

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Sabharwal, Nikant, Parthiban Arumugam, and Andrew Kelion. Myocardial perfusion scintigraphy: clinical value. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198759942.003.0010.

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Myocardial perfusion scintigraphy (MPS) is most commonly used to diagnose or exclude obstructive coronary disease in patients presenting with chest pain. This chapter covers the value of MPS in this context, as well as providing detail on the guidelines which help the clinician choose what investigations are appropriate for the patient presenting with chest pain. It also details a number of considerations related to the use of MPS, such as its cost-effectiveness and the prognosis value in the diagnosis of coronary artery disease compared to exercise ECG, X-ray computed tomographic coronary angiography, and other imaging investigations. Risk assessment prior to elective non-cardiac surgery is covered, with detailed attention paid to the challenges of assessing coronary artery disease special groups including women and patients with diabetes or renal disease. This chapter also covers assessment in known stable coronary artery disease, predicting the value of coronary revascularization and hibernating myocardium.
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Schmid, Jean-Paul, and Hugo Saner. Ambulatory preventive care: outpatient clinics and primary care. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656653.003.0023.

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Cardiac rehabilitation (CR) services aim to restore the physical, psychosocial, and vocational status of cardiac patients. The role of these services has evolved due to the progress of interventional cardiology with its prompt and effective treatment of acute coronary syndromes. The focus has moved from the restoration of a patient’s health following an acute event towards a more pronounced long-term targeted secondary prevention intervention. As a consequence, CR services have also expanded their indication in order to include not only patients after myocardial infarction or surgery but also a variety of ’non-acuteʼ cardiovascular disease (CVD) states like stable coronary heart disease and peripheral obstructive artery disease as well as asymptomatic patients with no history of CVD but with a constellation of cardiovascular risk factors, especially metabolic syndrome or diabetes mellitus. This chapter provides a wide-ranging summary of the issues concerning outpatients and primary care.
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Schmid, Jean-Paul, Hugo Saner, Paul Dendale, and Ines Frederix. Ambulatory preventive care: outpatient clinics and primary care. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199656653.003.0023_update_001.

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Cardiac rehabilitation (CR) services aim to restore the physical, psychosocial, and vocational status of cardiac patients. The role of these services has evolved due to the progress of interventional cardiology with its prompt and effective treatment of acute coronary syndromes. The focus has moved from the restoration of a patient’s health following an acute event towards a more pronounced long-term targeted secondary prevention intervention. As a consequence, CR services have also expanded their indication in order to include not only patients after myocardial infarction or surgery but also a variety of ’non-acuteʼ cardiovascular disease (CVD) states like stable coronary heart disease and peripheral obstructive artery disease as well as asymptomatic patients with no history of CVD but with a constellation of cardiovascular risk factors, especially metabolic syndrome or diabetes mellitus. This chapter provides a wide-ranging summary of the issues concerning outpatients and primary care.
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Thomas, Gregory S., L. Samuel Wann, and Myrvin H. Ellestad, eds. Ellestad's Stress Testing. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190225483.001.0001.

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The 6th edition of the textbook Ellestad’s Stress Testing: Principles and Practice was written for the new and veteran clinician alike performing stress testing. Thoroughly updated, referenced and interspersed with case examples, the book reviews how to get the most out exercise testing, without and with ancillary imaging. In addition to evaluation of ST segment depression, other powerful tools to detect ischemia and forecast the future are reviewed to increase the diagnostic accuracy and prognostic ability of exercise testing. The recognition and significance of exercise induced arrhythmias and conduction defects are examined. When to convert to pharmacologic stress or add ancillary imaging, including myocardial perfusion imaging, echocardiography, coronary calcium scoring, and magnetic reference imaging are reviewed. The use of stress testing in the management of obstructive and non-obstructive coronary artery disease (CAD), heart failure, cardiac rehabilitation, peripheral vascular disease, congenital heart and other cardiovascular diseases (CVD) is examined. Options to optimize the diagnostic capabilities of exercise and other diagnostic testing for women are highlighted. Strategic use of exercise testing in the face of a decreasing burden of CAD in the developed world, as well as the opportunity to rely on exercise testing as the first test to evaluate CVD in the developing world, are reviewed. The fundamentals of exercise physiology and myocardial ischemia that serve as the foundation for exercise testing in health and disease are explained.
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Taillefer, Raymond, and Frans J. Th Wackers. Kinetics of Conventional and New Cardiac Radiotracers. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0004.

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The kinetics of radiotracers, that is the mode of uptake, retention and release from the myocardium, are relevant for designing and implementing optimized nuclear cardiac imaging protocols. This chapter addresses the kinetics of commonly used radiotracers for imaging myocardial perfusion, sympathetic neuronal function and cardiac metabolism, both with SPECT and PET cardiac imaging. The optimal timing of imaging after injection either at stress or at rest is determined by rate of uptake in the heart and adjacent organs, as well as the residence time of radiotracers within the myocytes. The efficiency of myocardial extraction over a wide range myocardial blood flows is relevant for reliable detection of obstructive coronary artery disease and absolute quantification of regional myocardial blood flow. For each cardiac imaging agent the cellular mechanism of uptake and its release or retention are discussed with an emphasis on the clinical impact of these parameters.
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Book chapters on the topic "Lschaemia with no obstructive coronary artery disease"

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Niccoli, Giampaolo, Giancarla Scalone, and Filippo Crea. "Myocardial Infarction with Non-obstructive Coronary Artery Disease." In Microcirculation, 95–118. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-28199-1_7.

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Collins, J. J. "Comparison of Costs for Medical and Surgical Treatment of Coronary Obstructive Disease." In Return to Work After Coronary Artery Bypass Surgery, 279–84. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-69855-2_39.

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Lee, Suegene K., Jay Khambhati, and Puja K. Mehta. "Angina and Ischemia in Women with No Obstructive Coronary Artery Disease." In Gender Differences in the Pathogenesis and Management of Heart Disease, 101–33. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-71135-5_8.

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Kaski, Juan Carlos. "Angina due to Obstructive Atherosclerotic Coronary Artery Disease: Diagnosis and Patient Risk Stratification." In Essentials in Stable Angina Pectoris, 37–63. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-41180-4_3.

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Manolis, Athanasios J., Manolis S. Kallistratos, Demetrios V. Vlahakos, Asimina Mitrakou, and Leonidas E. Poulimenos. "Comorbidities Often Associated with Brain Damage in Hypertension: Diabetes, Coronary Artery Disease, Chronic Kidney Disease and Obstructive Sleep Apnoea." In Updates in Hypertension and Cardiovascular Protection, 35–46. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32074-8_4.

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van Erckelens, Franz, Th Hürter, Th Eitelberg, U. Krobok, Ch Reupcke, E. Schmitz, M. Sigmund, and P. Hanrath. "Effects of Inhaled Salbutamol and Oxitropium Bromide on Cardiopulmonary Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease and Coronary Artery Disease." In Computerized Cardiopulmonary Exercise Testing, 173–81. Heidelberg: Steinkopff, 1991. http://dx.doi.org/10.1007/978-3-642-85404-0_17.

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Mehta, Puja K., Janet Wei, and C. Noel Bairey Merz. "Angina in Patients with Evidence of Myocardial Ischemia and No Obstructive Coronary Artery Disease." In Chronic Coronary Artery Disease, 374–90. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-323-42880-4.00025-x.

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Peker, Yüksel, Karl A. Franklin, and Jan Hedner. "Coronary Artery Disease and Obstructive Sleep Apnea." In Principles and Practice of Sleep Medicine, 1264–70. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-323-24288-2.00128-8.

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Hedner, Jan, Karl A. Franklin, and Yüksel Peker. "Coronary Artery Disease and Obstructive Sleep Apnea." In Principles and Practice of Sleep Medicine, 1203–7. Elsevier, 2005. http://dx.doi.org/10.1016/b0-72-160797-7/50108-7.

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Hedner, Jan, Karl A. Franklin, and Yüksel Peker. "Coronary Artery Disease and Obstructive Sleep Apnea." In Principles and Practice of Sleep Medicine, 1393–99. Elsevier, 2011. http://dx.doi.org/10.1016/b978-1-4160-6645-3.00121-3.

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Conference papers on the topic "Lschaemia with no obstructive coronary artery disease"

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Poberezhets, Vitalii, Yuriy Mostovoy, and Hanna Demchuk. "Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease and coronary artery disease." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa662.

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Ford, Tom, Richard Good, Paul Rocchiccioli, Margaret McEntegart, Stuart Watkins, Hany Eteiba, Aadil Shaukat, et al. "50 Ischaemia and No Obstructive Coronary Artery Disease (INOCA): prevalence and predictors of coronary vasomotion disorders." In British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019. BMJ Publishing Group Ltd and British Cardiovascular Society, 2019. http://dx.doi.org/10.1136/heartjnl-2019-bcs.48.

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Touil, Amany, Ferdaous Yangui, Saoussen Antit, Lilia Zakhama, Soraya Ben Youssef, and Mohamed Ridha Charfi. "Prevalence of chronic obstructive pulmonary disease (COPD) among smokers with stable coronary artery disease (CAD)." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa5014.

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Alharbi, Fawaz, Jasdeep Sohal, Savita Sharma, Rakesh C. Arora, Darren Freed, Joel Zivot, Alan H. Menkis, Micheal Raabe, and Sat Sharma. "Increased Mortality And Morbidity After Coronary Artery Bypass Grafting In Chronic Obstructive Pulmonary Disease." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2383.

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Arvidsson, Ida, Niels Christian Overgaard, Kalle Astrom, Anders Heyden, Miguel Ochoa Figueroa, Jeronimo Frias Rose, and Anette Davidsson. "Prediction of Obstructive Coronary Artery Disease from Myocardial Perfusion Scintigraphy using Deep Neural Networks." In 2020 25th International Conference on Pattern Recognition (ICPR). IEEE, 2021. http://dx.doi.org/10.1109/icpr48806.2021.9412674.

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Peker, Yuksel, Baran Balcan, Helena Glantz, and Erik Thunström. "Polysomnographic characteristics and cardiac function in coronary artery disease patients with nonsleepy obstructive sleep apnoea." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.oa4965.

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Lowe, K., C. Thiele, E. L. Port, C. Wilson, S. M. Humphries, D. A. Lynch, H. Lindsey, et al. "Osteoporosis, Coronary Artery Calcification, and Chronic Obstructive Pulmonary Disease (COPD) in a Lung Cancer Screening Cohort." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4890.

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Kharchenko, Iuliia, Olena Krakhmalova, and Olena Izmailova. "The relationship between the severity of obstructive sleep apnea syndrome and severity of chronic obstructive pulmonary disease (COPD) associated with coronary artery disease (CAD)." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa640.

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Gorokhova, S., N. Belozerova, and M. Buniatyan. "OBSTRUCTIVE SLEEP APNEA / HYPOPNEA SYNDROME IN RAILWAY WORKERS WITH RISK FACTORS FOR CORONARY HEART DISEASE." In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-155-158.

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Abstract: Obstructive sleep apnea/hypopnea syndrome (OSA) is a common condition that may lead to excessive daytime sleepiness, cognitive disturbance, and a decreased concentration that are associated with the risk of workplace accidents and injuries. It is difficult to diagnose OSA due to low severity and specificity of its symptoms and special requirements in respect of medical resources. We assumed that it would be more effective and cost-efficient to diagnose OSA in railway workers with such risk factors f coronary heart disease as arterial hypertension and metabolic disorders since this group receives comprehensive medical attention. However, no studies on the prevalence of OSA in railway workers specifically considered the risk factors for coronary artery disease. The aim of the study was to assess the prevalence of OSA in railway workers with confirmed cardiovascular and metabolic disorders that did not disqualify them from their job. Material and methods. The study included 967 railway workers (locomotive drivers and their assistants). On Stage 1, a group of participants suspected OSA was selected; and on Stage 2, a group of participants with confirmed OSA was formed. Polysomnography or cardiorespiratory monitoring were used to diagnose OSA. Results. We developed a two-step algorithm of OSA diagnosis that included a preliminary assessment of the probability of OSA. 236 (24.4%) participants with a probability of OSA were selected among the initial 967 persons with risk factors for coronary artery disease. Further assessment confirmed OSA in 141 (60%) participants in this group. The analysis of distribution of risk factors for coronary artery disease and OSA showed that 125 (53.0%) of patients with BMI ≥ 30 kg/m², 115 (48.7%) of patients with AH, and 26 (11.0%) of patients with type 2 diabetes had OSA; most of them had some combination of these risk factors. Conclusions: OSA is prevalent in the group of professionally active locomotive drivers and their assistants with risk factors for coronary heart disease; every second worker in a target group with BMI ≥ 30 kg/m², AH or with both risk factors was diagnosed with OSA. The proposed two-step algorithm with a pre-test assessment of OSA probability and subsequent instrumental examination (cardiorespiratory monitoring, polysomnography) allows to accurately diagnosis OSA and allocate medical resources in a cost-effective manner.
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Macrea, M., R. L. ZuWallack, T. J. Martin, K. A. Oursler, and A. Malhotra. "Exercise Cardiac Power and Coronary Artery Disease Mortality Risk in Patients with Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA) Overlap Syndrome (OS)." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2281.

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Reports on the topic "Lschaemia with no obstructive coronary artery disease"

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Treadwell, Jonathan R., James T. Reston, Benjamin Rouse, Joann Fontanarosa, Neha Patel, and Nikhil K. Mull. Automated-Entry Patient-Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes. Agency for Healthcare Research and Quality (AHRQ), March 2021. http://dx.doi.org/10.23970/ahrqepctb38.

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Background. Automated-entry consumer devices that collect and transmit patient-generated health data (PGHD) are being evaluated as potential tools to aid in the management of chronic diseases. The need exists to evaluate the evidence regarding consumer PGHD technologies, particularly for devices that have not gone through Food and Drug Administration evaluation. Purpose. To summarize the research related to automated-entry consumer health technologies that provide PGHD for the prevention or management of 11 chronic diseases. Methods. The project scope was determined through discussions with Key Informants. We searched MEDLINE and EMBASE (via EMBASE.com), In-Process MEDLINE and PubMed unique content (via PubMed.gov), and the Cochrane Database of Systematic Reviews for systematic reviews or controlled trials. We also searched ClinicalTrials.gov for ongoing studies. We assessed risk of bias and extracted data on health outcomes, surrogate outcomes, usability, sustainability, cost-effectiveness outcomes (quantifying the tradeoffs between health effects and cost), process outcomes, and other characteristics related to PGHD technologies. For isolated effects on health outcomes, we classified the results in one of four categories: (1) likely no effect, (2) unclear, (3) possible positive effect, or (4) likely positive effect. When we categorized the data as “unclear” based solely on health outcomes, we then examined and classified surrogate outcomes for that particular clinical condition. Findings. We identified 114 unique studies that met inclusion criteria. The largest number of studies addressed patients with hypertension (51 studies) and obesity (43 studies). Eighty-four trials used a single PGHD device, 23 used 2 PGHD devices, and the other 7 used 3 or more PGHD devices. Pedometers, blood pressure (BP) monitors, and scales were commonly used in the same studies. Overall, we found a “possible positive effect” of PGHD interventions on health outcomes for coronary artery disease, heart failure, and asthma. For obesity, we rated the health outcomes as unclear, and the surrogate outcomes (body mass index/weight) as likely no effect. For hypertension, we rated the health outcomes as unclear, and the surrogate outcomes (systolic BP/diastolic BP) as possible positive effect. For cardiac arrhythmias or conduction abnormalities we rated the health outcomes as unclear and the surrogate outcome (time to arrhythmia detection) as likely positive effect. The findings were “unclear” regarding PGHD interventions for diabetes prevention, sleep apnea, stroke, Parkinson’s disease, and chronic obstructive pulmonary disease. Most studies did not report harms related to PGHD interventions; the relatively few harms reported were minor and transient, with event rates usually comparable to harms in the control groups. Few studies reported cost-effectiveness analyses, and only for PGHD interventions for hypertension, coronary artery disease, and chronic obstructive pulmonary disease; the findings were variable across different chronic conditions and devices. Patient adherence to PGHD interventions was highly variable across studies, but patient acceptance/satisfaction and usability was generally fair to good. However, device engineers independently evaluated consumer wearable and handheld BP monitors and considered the user experience to be poor, while their assessment of smartphone-based electrocardiogram monitors found the user experience to be good. Student volunteers involved in device usability testing of the Weight Watchers Online app found it well-designed and relatively easy to use. Implications. Multiple randomized controlled trials (RCTs) have evaluated some PGHD technologies (e.g., pedometers, scales, BP monitors), particularly for obesity and hypertension, but health outcomes were generally underreported. We found evidence suggesting a possible positive effect of PGHD interventions on health outcomes for four chronic conditions. Lack of reporting of health outcomes and insufficient statistical power to assess these outcomes were the main reasons for “unclear” ratings. The majority of studies on PGHD technologies still focus on non-health-related outcomes. Future RCTs should focus on measurement of health outcomes. Furthermore, future RCTs should be designed to isolate the effect of the PGHD intervention from other components in a multicomponent intervention.
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