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Academic literature on the topic 'Lpt complex'

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Published: 9 March 2023
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Journal articles on the topic "Lpt complex"

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Shin, Jeong Bin, Seong Min Lee, Myeongcheol Kim, Donghyuk Kim, Duk Young Jeon, and Kyung Cheol Choi. "Plasmonically Enhanced Optical Characteristics From Europium Organometallic Complex." IEEE Photonics Technology Letters 25, no. 23 (December 2013): 2342–45. http://dx.doi.org/10.1109/lpt.2013.2285257.

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Engin, D. "Complex Optical Low Coherence Reflectometry (OLCR) With Tunable Source." IEEE Photonics Technology Letters 16, no. 5 (May 2004): 1346–48. http://dx.doi.org/10.1109/lpt.2004.826103.

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Foster, Scott. "Complex Susceptibility of Saturated Erbium-Doped Fiber Lasers and Amplifiers." IEEE Photonics Technology Letters 19, no. 12 (June 2007): 895–97. http://dx.doi.org/10.1109/lpt.2007.896625.

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Adams, D. B., and C. K. Madsen. "Complex Optical Spectrum Analysis Using a Tunable Dispersive Optical Filter." IEEE Photonics Technology Letters 20, no. 2 (January 2008): 90–92. http://dx.doi.org/10.1109/lpt.2007.911507.

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Teng, J. H., L. F. Chong, J. R. Dong, S. J. Chua, S. S. Ang, Y. J. Wang, and E. L. Lim. "Complex-Coupled DFB Laser Using a Buried SiO$_{2}$ Grating." IEEE Photonics Technology Letters 20, no. 4 (February 2008): 231–33. http://dx.doi.org/10.1109/lpt.2007.913262.

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Li, Wei, Wen Ting Wang, Wen Hui Sun, Jian Guo Liu, and Ning Hua Zhu. "Microwave Photonic Notch Filter With Complex Coefficient Based on DDMZM." IEEE Photonics Technology Letters 26, no. 18 (September 15, 2014): 1859–62. http://dx.doi.org/10.1109/lpt.2014.2320459.

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Greenberg, M., and M. Orenstein. "Filterless "Add" multiplexer based on novel complex gratings assisted coupler." IEEE Photonics Technology Letters 17, no. 7 (July 2005): 1450–52. http://dx.doi.org/10.1109/lpt.2005.848560.

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Lysak, V. V., I. A. Sukhoivanov, O. V. Shulika, I. M. Safonov, and Y. T. Lee. "Carrier tunneling in complex asymmetrical multiple-quantum-well semiconductor optical amplifiers." IEEE Photonics Technology Letters 18, no. 12 (June 2006): 1362–64. http://dx.doi.org/10.1109/lpt.2006.877334.

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Loayssa, A., J. Capmany, M. Sagues, and J. Mora. "Demonstration of incoherent microwave photonic filters with all-optical complex coefficients." IEEE Photonics Technology Letters 18, no. 16 (August 2006): 1744–46. http://dx.doi.org/10.1109/lpt.2006.879535.

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Villafranca, A., J. Lasobras, R. Alonso, F. M. Lopez, and I. Garces. "Complex Spectrum Analysis of Modulated Optical Signals Using Stimulated Brillouin Scattering." IEEE Photonics Technology Letters 20, no. 23 (December 2008): 1938–40. http://dx.doi.org/10.1109/lpt.2008.2005423.

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Dissertations / Theses on the topic "Lpt complex"

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CARDOSO, MENDES MOURA ELISABETE CRISTINA. "TARGETING THE LIPOPOLYSACCHARIDE TRANSPORT TO DEVELOP NOVEL ANTIMICROBIAL DRUGS." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/789419.

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The emergence of multidrug-resistant strains of Gram-negative pathogens that rapidly spread in the clinic is of great concern, since the range of antibiotics still effective against these organisms is limited and will continue to diminish. Therefore, the identification of novel and unexplored drug targets is an urgent need. Gram-negative bacteria possess an outer membrane (OM) with highly selective permeability properties due to its asymmetric structure with LPS in the outer leaflet and phospholipids in the inner leaflet. Dissecting the biogenesis of the OM and gaining insights into the multiprotein machineries that assemble this structure is vital if we want to succeed in developing novel antibiotic compounds that can target these machineries. This thesis focuses on the machinery that transports lipopolysaccharide (LPS) to the cell surface: the LPS transport (Lpt) machinery. In Escherichia coli, the Lpt system is composed of seven essential proteins spanning the cell envelope: the ABC transporter LptB2FGC powers the LPS extraction from the inner membrane (IM) and its transport along the periplasmic bridge, comprising LptA, to the OM LptDE translocon, which assembles LPS on the cell surface. Due to its vital role in cell physiology, the Lpt system represents a good target for the development of antibiotics with an innovative mechanism of action. Encouragingly, two promising inhibitors of this machinery have been discovered: murepavadin, which is currently in preclinical development, and thanatin. The research project of this thesis focuses on two main topics: elucidating the mechanism behind thanatin’s antibacterial activity, and the characterization of a mutant six-component Lpt machinery that is functional without LptC. Thanatin is a host-defence antimicrobial peptide recently shown to cause defects in membrane assembly and to bind to the N-terminal β-strand of LptA in vitro (Vetterli et al., 2018). Since this region is involved in both LptA dimerization and interaction with LptC, we implemented the Bacterial Adenylate Cyclase Two-Hybrid (BACTH) system to detect these interactions in the periplasm and probe which is the target of thanatin. With this technique, we found that thanatin targets both interactions and has a stronger inhibitory effect on the LptC-LptA interaction (Moura et al., 2020: https://doi.org/10.3389/fmicb.2020.00909). Further demonstrating a direct effect upon the LPS transport, we observed in thanatin-treated cells the degradation of LptA and the accumulation of LPS decorated with colanic acid (Moura et al., 2020), both of which have been previously reported to be indicative of LPS transport defects (Sperandeo et al., 2008, 2011). We further explored how thanatin affects the integrity of the cell envelope and observed that it induces promoters regulated by envelope-specific stress response systems (unpublished data). Although all seven Lpt proteins have been shown to be essential, viable mutants lacking LptC but carrying suppressor mutations at the residue R212 in the periplasmic domain of LptF were isolated by our group (Benedet et al., 2016). Interestingly, LptC was recently proposed to have a regulatory role on the LptB2FGC transporter by modulating its ATPase activity (Owens et al., 2019; Li et al., 2019), thus adding to the mystery of how the suppressor mutants can survive without LptC. In the second part of the project, we elucidated how the cell can bypass the presence of LptC and its regulatory role in the machinery by performing a biochemical characterization of the most representative suppressor mutant (manuscript ready for submission). Moreover, by analysing the interaction networks around the residue R212 of LptF, we also formulated a putative mechanism adopted by the Lpt transporter to regulate LPS transfer from LptB2FGC to LptA.
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Sreeramakavacham, Bindu. "FILM GROWTH OF NOVEL FREQUENCY AGILE COMPLEX-OXIDE PIEZOELECTRIC MATERIAL." Master's thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3104.

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Piezoelectric materials are well known for their applications in surface (SAW) and bulk acoustic wave (BAW) devices such as oscillators, resonators and sensors. Quartz has been the main material used in such applications. Ternary calcium gallium germanate (CGG) structure-type materials, so-called langasites, recently emerged as very promising because of their piezoelectric properties superior to quartz. This thesis discusses the growth of langasite-type La3Ga5.5Ta0.5O14 (LGT) films by liquid phase epitaxy (LPE) technique and their chemical and structural characterization. In addition, the different techniques suitable for the growth of LGT are discussed and compared. To adjust the materials properties for given applications, doping by selected ions can be used. However, the dopants must be homogeneously distributed. In the current study, Al, Ti, Cr and Ca were investigated as dopants. In an earlier study, Al and Ti had been chosen because of their ability to substitute the octahedral site of LGT, normally occupied by Ga (CN=VI) with a segregation coefficient near unity in Czochralski growth. Doping with Ca and Cr has never been reported before, and therefore, the segregation behavior was unknown. In this study, Al, Ti and co-doping with Cr and Ca has been investigated for both X and Y-oriented films. The dopant distribution in the films was quantitatively evaluated by Secondary Ion Mass Spectroscopy (SIMS), using ion-implanted LGT substrates as standards. The drop of dopant concentration, in the SIMS profile, allows for the identification of the film-substrate interface and to accurately measure the thickness of the films. The film thickness is found to be typically of the order 0.5 to 2µm, depending on growth conditions. The solvent was found a reliable choice, as solvent ions were not incorporated in the films above the detection limits of the characterization techniques. A lead oxide solvent system is used as a solvent for the growth of LGT LPE films with different orientations. Extensive structural characterization was performed. The crystallinity of substrates and films grown with different orientations was compared by X-ray diffraction (XRD). The films show a very high structural perfection, with typically FWHM values of 0.035 for the (004) reflection of the XRD rocking curve. The films were also characterized by TEM. The optical transmittance of the films was characterized by Varian optical spectrophotometer, and the value obtained of approximately 80% is comparable with the transmittance value of the Czochralski grown polished substrate.
M.S.M.S.E.
Department of Mechanical, Materials and Aerospace Engineering
Engineering and Computer Science
Materials Science & Engr MSMSE
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Bodewits, Karin. "Biosynthesis pathway & transport of endotoxin : promising antibacterial drug targets in the Burkholderia cepacia complex (BCC)." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5791.

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Burkholderia cepacia complex (Bcc) species are opportunistic pathogens in patients with cystic fibrosis (CF), which are able to cause lethal infections. The Bcc are inherently resistant to most classes of antibiotics, which makes successful treatment problematic. Lipid A (also known as endotoxin), the hydrophobic anchor of lipopolysaccaride (LPS), is the bio-active component of LPS. One of several unique characteristics of the lipid A of the Bcc, is the permanent attachment of 4-amino-4-deoxy-L-arabinose (L-Ara4N) to the lipid A molecule. Also, the genes involved in L-Ara4N biosynthesis are necessary for viability in B. cenocepacia. Here we present research on lipid A biosynthesis, modi cation, and transport in the Bcc and highlight promising antimicrobial targets. The synthetic antibiotic CHIR-090 is an inhibitor of LpxC, an enzyme involved in the lipid A biosynthetic pathway. I investigated the activity of CHIR-090 against the Bcc and found that sensitivity to this antibiotic was both species- and strain-specific. CHIR-090 displayed MICs between 0.1 and 12.5 μg/ml against a panel of B. multivorans, the most prevalent Burkholderia species in CF. The species- and strain-specific sensitivity towards CHIR-090 was further explored and a strong correlation was found between the presence of a unique open reading frame, named LpxC2, in resistant species. To address the problem of multiple drug-resistance of the Bcc, we investigated the activity of the pyridoxal 50-phosphate (PLP)-dependent enzyme inhibitor cycloserine (CS) against the Bcc. CS is used as a second line of defense against M. tuberculosis. The activity of the D-enantiomer of CS (DCS) against the Bcc was tested and displayed MICs between 2 and 128 μg/ml and acted bactericidal towards the Bcc. Additionally, DCS inhibition of recombinant ArnB from B. cenocepacia J2315, a PLP-dependent enzyme necessary for viability in the Bcc, was studied. ArnB was inhibited reversibly by DCS. ArnB was further explored as a promising drug-target in the Bcc, but only CS has been identified as an inhibitor so far. In this thesis it was attempted to find the reason why is L-Ara4N modification of lipid A necessary for viability in B. cenocepacia. Therefore, two proteins were characterised, which are involved in lipid A transport: LptA, the periplasmic lipid A binding protein, and LptB, the cytoplasmic ATP-ase. LptA was found to be able to bind both modified and unmodified lipid A in vitro and therefore is not L-Ara4N specific. Furthermore, LptA could bind deep-rough-, rough-, and smooth- LPS, similar to that described for Escherichia coli LptA. The kinetic parameters of LptB were determined in vitro (kcat = 5.71 min-1 and KM = 0.88 mM), and were comparable to E. coli LptB. The ATP-ase activity of LptB was not influenced by the presence of any forms of LPS (modified or non-modified). Therefore, we concluded that both B. cenocepacia J2315 LptA and LptB are not L-Ara4N specific.
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Shen, Xueying. "Complex lot Sizing problem with parallel machines and setup carryover." Thesis, Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLED057/document.

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Dans cette thèse, nous étudions deux problèmes de planification de production motivés par des applications du monde réel. Tout d'abord, un problème de planification de production pour un projet de fabrication de vêtements est étudié et un outil d'optimisation est développé pour le résoudre. Deuxièmement, une version restreinte du problème de dimensionnement du lot de capacité avec des configurations dépendantes de la séquence est explorée. Diverses formulations mathématiques sont développées et une analyse de complexité est effectuée pour donner une première analyse du problème
In this thesis, we study two production planning problems motivated by challenging real-world applications. First, a production planning problem for an apparel manufacturing project is studied and an optimization tool is developed to tackle it. Second, a restricted version of the capacitated lot sizing problem with sequence dependent setups is explored. Various mathematical formulations are developed and complexity analysis is performed to offer a first glance to the problem
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Kelm, Travis R. "LOT complexes and the Whitehead conjecture /." view abstract or download file of text, 2002. http://wwwlib.umi.com/cr/uoregon/fullcit?p3055693.

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Thesis (Ph. D.)--University of Oregon, 2002.
Typescript. Includes vita and abstract. Includes bibliographical references (leaves 71-73). Also available for download via the World Wide Web; free to University of Oregon users.
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Charles, Mehdi. "Modeling and solving complex multi-item lot-sizing problems with inventory constraints." Thesis, Lyon, 2021. http://www.theses.fr/2021LYSEM039.

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Nous nous sommes intéressés au problème de lot-sizing multi-produits avec capacité, temps de lancement et ventes perdues. Nous avons étendu ce problème afin de prendre en compte des aspects industriels importants, en particulier des contraintes sur les stocks. Nous avons d'abord étudié les effets de fin d’horizon des solutions aux problèmes de lot-sizing, qui peuvent entraîner des coûts importants même pour des horizons temporels très longs. Pour compenser ces effets, nous avons proposé de rajouter une contrainte de stock final minimal ainsi que des contraintes de stock maximal par produit. Ces valeurs ont été déduites d'une analyse d'un problème de lot-sizing cyclique avec temps de lancement et capacité dont la relaxation linéaire peut être résolue de manière analytique. Par la suite, nous nous sommes intéressés à la modélisation de l'évolution des stocks intra-périodes. Cet aspect est particulièrement important lorsque les capacités de stockage sont limitées. Nous avons proposé des nouvelles contraintes qui différent en fonction des hypothèses sur la production et la demande. L'objectif est de limiter les excès et les déficits de stock lors de l'ordonnancement détaillé du plan de production à chaque période. Nos résultats numériques ont montré que ces nouvelles contraintes permettent de construire des plans de production respectant davantage les contraintes sur les stocks. Des méthodes de résolution génériques et plus particulièrement des méthodes de décomposition (relaxation Lagrangienne, relax-and-fix) ont été développées. Une approche originale de parallélisation a été proposée, dont l’objectif est de réduire la taille des sous-problèmes à résoudre et d'utiliser les outils disponibles à DecisionBrain. L'objectif final de cette thèse a été l'implémentation des heuristiques proposées dans l'outil d'optimisation développé par DecisionBrain ainsi que des tests de performance sur des instances industrielles
In this thesis, we considered the capacitated multi-item lot-sizing problem with setup times and lost sales. We extended this problem to take into account important industrial aspects, especially with regards to inventory management. We first studied the end-of-horizon effects on optimal solutions of lot-sizing problems that, even on a rolling horizon, can lead to important additional costs. To reduce these effects, we have added a global minimum ending inventory constraint as well as a maximum ending inventory constraint for each item. These values were deduced from the analysis of a cyclical capacitated lot-sizing problem with setup times, whose linear relaxation can be analytically solved. Then, we modeled the inventory evolution within each period. This point is especially relevant when the storage capacity is limited. We added new inventory constraints to better respect inventory bounds when scheduling productions within each period. The constraints differ based on hypotheses on the shapes of evolution of production and demand. Numerical experiments showed that these new constraints enable to schedule production plans with a better inventory management. Decomposition approaches (Lagrangian relaxation, relax-and-fix) were developed in order to propose generic approaches to solve capacitated lot-sizing problems with setup times. An original use of parallelization was proposed in order to reduce the size of the subproblems to solve and to use Decisionbrain's tools.Finally, the parallelized relax-and-fix was implemented into DecisionBrain's optimization tool and tests were performed on industrial instances
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Yang, Yiying. "Mécanismes de biogenèse et de maintien de la membrane externe des bactéries à Gram négatif." Thesis, Toulouse 3, 2021. http://www.theses.fr/2021TOU30279.

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Les bactéries à Gram négatif comprennent un certain nombre d'agents pathogènes animaux redoutables qui sont particulièrement résistants aux thérapies antibiotiques grâce à la fonction protectrice de leur enveloppe bactérienne. L'enveloppe des bactéries à Gram négatif est composée d'une membrane interne (MI) et d'une membrane externe (ME), séparées par un espace, le périplasme, contenant le peptidoglycane (PG). Le feuillet externe de la bicouche de la ME contient des lipopolysaccharides (LPS) qui forment une barrière imperméable à certaines molécules toxiques, tels que les détergents ou des petites molécules hydrophobes. Les nutriments sont transportés par les protéines (OMP) de la ME. D'autres OMP remplissent des fonctions de biogenèse de l'enveloppe, notamment l'assemblage des OMP et des LPS. Les OMP sont assemblées dans la ME par le complexe d'assemblage en tonneau bêta (BAM), un hétéro-pentamère contenant l'OMP essentielle BamA et quatre lipoprotéines BamBCDE. L'assemblage du LPS nécessite une autre OMP essentielle, LptD, qui s'associe de manière stable avec la lipoprotéine LptE. Un assemblage défectueux des OMP provoque un stress de l'enveloppe et rend les bactéries Gram-négatives sensibles aux antibiotiques et aux détergents. Le complexe BAM représente donc une cible prometteuse pour le développement de nouveaux antibiotiques. La fonction moléculaire du complexe BAM dans la biogénèse des ME est mal comprise. En utilisant une stratégie de spectrométrie de masse quantitative, le laboratoire d'accueil a récemment identifié deux nouveaux interacteurs putatifs du complexe BAM, les lipoprotéines DolP (anciennement YraP) et YifL, toutes deux de fonctions inconnues. L'objectif de ce travail de thèse était de caractériser les rôles respectifs de DolP et YifL au sein du complexe BAM. DolP est une lipoprotéine de la ME de 20 kDa. L’accumulation d’OMP mal repliées dans le périplasme induit un stress de l’enveloppe qui, à son tour, stimule la production à la fois de BamA et de DolP. Cependant, le rôle de cette dernière dans la biogenèse des OMP n’est pas connu. Dans cette étude, en utilisant un crible génétique, nous avons montré que DolP est critique pour la croissance des cellules qui subissent un stress d'enveloppe. Nous avons montré que l’accumulation de BamA dans la ME est toxique pour les cellules mais que DolP est capable de contrecarrer cette toxicité en favorisant le bon repliement de BamA (Ranavaco-first; Yangco-first; Orenday-Tapiaco-first, et al., 2021). En parallèle, la caractérisation de l'interaction BAM-YifL a permis de montrer que YifL interagit avec BamA et BamD. De manière intéressante, nous avons découvert que YifL interagit également avec la machinerie de sécrétion des LPS, LptDE, qui est assemblée par le complexe BAM dans la ME. Ce processus nécessite également la machinerie de repliement oxydatif DsbA pour oxyder les 4 résidus de cystéine dans LptD de façon séquentielle. Une analyse génétique a montré que la délétion de yifL exacerbe la sensibilité des cellules bamB ou dsbA au SDS, un détergent normalement exclu par la couche de LPS. Nous avons constaté qu'en l'absence de YifL, LptD se fixe transitoirement au complexe BAM sous une forme intermédiaire partiellement oxydée. L'oxydation efficace de LptD pour former une protéine mature et fonctionnelle nécessite YifL. Nos résultats révèlent pour la première fois que YifL est critique pour la biogenèse efficace du complexe LptDE
Gram-negative bacteria include a number of dreadful animal pathogens that are particularly resistant to antibiotic therapies thanks to the sheltering function of their bacterial envelope. The envelope is composed of an inner and an outer membrane (IM and OM), and the separating periplasm containing the peptidoglycan (PG). The outer leaflet of the OM bilayer largely consists of lipopolysaccharide (LPS) that forms a permeability barrier against toxic molecules, including detergents and small hydrophobic molecules. Nutrients are transported via OM-spanning proteins (OMPs). Other OMPs perform envelope biogenesis functions, including the assembly of OMPs and LPS. OMPs are assembled into the OM by the beta-barrel assembly machinery (BAM), a heteropentamer containing the essential OMP BamA and four lipoproteins BamBCDE. The assembly of LPS requires another essential OMP, LptD, which stably associates with the lipoprotein LptE. Defective assembly of OMPs causes envelope stress and renders Gram-negative bacteria sensitive to antibiotics and detergents. Hence, the BAM complex represents a promising target for the development of new therapies. The mechanistic details of how the BAM complex functions ensuring efficient OM biogenesis are only marginally understood. By using a quantitative mass-spectrometry strategy the hosting lab has recently identified two novel putative interactors of the BAM complex of Escherichia coli, the lipoproteins DolP (formerly YraP) and YifL, both of unknown functions. The aim of this PhD thesis work was to characterize the roles of DolP and YifL at the BAM complex. DolP is a ~20 kDa OM lipoprotein that localizes in the periphery of E. coli cells and accumulates at the mid-cell specifically during a late step of cell division. DolP is upregulated during envelope stress caused by the accumulation of unfolded OMPs in the periplasm. Whether DolP plays any role in OMP biogenesis, however, was unknown. In this study, by using a genetic screen, we have shown that DolP is critical for the fitness of cells that undergo envelope stress. We have demonstrated that an increment of BamA in the OM, which is also upregulated during envelope stress, is potentially toxic for the cells. We provide evidence that DolP promotes proper folding and function of BamA thereby counteracting its toxicity. The mid-cell recruitment of DolP had been linked to regulation of septal peptidoglycan hydrolysis by an unknown mechanism. Our study reveals that during envelope stress DolP loses its association with the mid-cell, thus revealing a mechanistic link between impaired OMP biogenesis and a late step of cell division (Ranavaco-first; Yangco-first; Orenday-Tapiaco-first, et al., 2021). Next the BAM-YifL interaction was characterized. We showed that the ~7 kDa YifL interacts with BamA and BamD. Interestingly, we have found that YifL also interacts with the LPS secretory machinery LptDE, which is assembled by the BAM complex into the OM
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Nebenfuhr, Mario T. "The LPS-Receptor Complex on Human Monocytes Investigated using Single Particle Fluorescence Imaging and Proteomics." Thesis, University of Essex, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520101.

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Attallah, Aly [Verfasser]. "Distributed Control for Complex Mission Scenarios With Non-Holonomic Agents - An LPV Approach / Aly Attallah." München : Verlag Dr. Hut, 2021. http://d-nb.info/1238423078/34.

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Carvalho, Jozélio Freire de. ""Antilipoproteína lipase (LPL): um novo componente no complexo processo aterosclerótico do lúpus eritematoso sistêmico?"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5145/tde-27092005-130705/.

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Dislipidemia é implicada no processo aterosclerótico do LES. A descrição de aLPL no LES associado a hipertrigliceridemia levou-nos a analisar esse anticorpo no contexto da inflamação envolvida na aterogênese. aLPL foi encontrado em 38% dos pacientes com LES com altos níveis de triglicérides. Correlação positiva significante foi observada entre aLPL e PCR, VHS, SLEDAI, anti-DNA, anti-cardiolipina e CH100 baixo. Análise de regressão múltipla confirmou a forte associação entre aLPL e PCR. Esses dados dão suporte à associação entre inflamação, resposta imune e dislipidemia, introduzindo o aLPL como um novo componente nos complexos eventos da aterogênese do LES
Dyslipidemia is implicated in the atherosclerosis process of SLE. The description of aLPL in SLE associated with hypertrigliceridemia prompted us to analyze this antibody in the context of the inflammation involved in the atherogenesis. aLPL was found in 38 por cento of SLE patients with high levels of triglycerides. Significant positive correlation was observed between aLPL and CRP, ESR, SLEDAI, anti-DNA, anti-cardiolipin and low CH100. Multiple regression analysis confirmed the strong association between aLPL and CRP. These data support the link between inflammation, immune response and dyslipidemia, introducing anti-LPL as new player in the complex events of atherogenesis in SLE
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Books on the topic "Lpt complex"

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Ant︠s︡ev, G. V. 55 let na sluzhbe Otechestvu. Sankt-Peterburg: Svetoch, 2005.

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Izumi, Hideaki. Non-commutative Lp-spaces constructed by the complex interpolation method. Sendai, Japan: Tohoko University, 1998.

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Sherstobitova, P. A. Zakaz gosudarstvennoĭ vazhnosti: Khabarovskomu radiotekhnicheskomu zavodu--65 let : 1950-2010. Khabarovsk: Priamurskie vedomosti, 2010.

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Baranov, Leonid Timofeevich. Kosmodrom Baĭkonur: 50 kosmicheskikh let. Karaganda: Rekslaĭd, 2005.

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Torre, Michel de La. Lot-et-Garonne: [le guide complet de ses 317 communes] : histoire, géographie, nature, arts. Paris: Deslogis-Lacoste, 1990.

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P, Goodstein L., Nordic Liaison Committee for Atomic Energy., and NKA Project LIT-3, eds. Computer aided operation of complex systems: Experimental testing and evaluation : final report of the NKA projects LIT-3.2 and 3.3. [S.l.]: Nordic Liaison Committee for Atomic Energy, 1985.

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1965-, Sabadini Irene, Struppa Daniele Carlo 1955-, and SpringerLink (Online service), eds. Noncommutative Functional Calculus: Theory and Applications of Slice Hyperholomorphic Functions. Basel: Springer Basel AG, 2011.

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Division, San Francisco (Calif ). Office of the Controller City Services Auditor. Recreation and Park Commission: Concession audit of the Harding Park Golf Course Complex, July 1, 2004 through June 30, 2005. San Francisco: Office of the Controller, 2006.

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Bakhoum, Mourad M., and Juan A. Sobrino, eds. Case Studies of Rehabilitation, Repair, Retrofitting, and Strengthening of Structures. Zurich, Switzerland: International Association for Bridge and Structural Engineering (IABSE), 2010. http://dx.doi.org/10.2749/sed012.

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<p>This document provides case studies of structural rehabilita-tion, repair, retrofitting, strengthening, and upgrading of structures, which might be encompassed – in short – by the convenient umbrella terms “Conservation / Upgrading of Existing Structures”. The selected studies presented in this SED cover a variety of structural types from different countries.</p> <p>Strengthening and rehabilitation of structures is usually a challenge because of uncertainties associated with old struc-tures and difficulties due to restrictions on the geometry and materials used, as well as other structural or functional con-straints. When repairing an existing structure the engineers involved have plenty of possibilities, lots of constraints, and in some cases there are no applicable codes. Strengthening and rehabilitating is sometimes a complex and exciting work; an art.</p> <p>The book is a summary of practices to help structural engineers. The reader of this book will discover different approaches to put forward strengthening or rehabilitation projects. Even identical technical problems could have very different efficient solutions, as discussed in the papers, considering structural, environmental, economic factors, as well as contractor and designer experience, materials, etc.</p>
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Gdanskiy, Nikolay. Fundamentals of the theory and algorithms on graphs. ru: INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/978686.

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The textbook describes the main theoretical principles of graph theory, the main tasks to be solved using graph structures, and General methods of their solution and specific algorithms, with estimates of their complexity. I covered a lot of the examples given questions to test knowledge and tasks for independent decisions. Along with the control tasks to verify the theoretical training provided practical assignments to develop programs to study topics of graph theory. Meets the requirements of Federal state educational standards of higher education of the last generation. Designed for undergraduate and graduate programs, studying information technology, for in-depth training in analysis and design of systems of complex structure. Also the guide can be useful to specialists of the IT sphere in the study of algorithmic aspects of graph theory.
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Book chapters on the topic "Lpt complex"

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Björner, Anders. "“Let Δ be a Cohen-Macaulay complex …”." In The Mathematical Legacy of Richard P. Stanley, 105–18. Providence, Rhode Island: American Mathematical Society, 2016. http://dx.doi.org/10.1090//mbk/100/06.

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Shrank, Cathy, and Raphael Lyne. "‘Let the Bird of Loudest Lay’." In The Complete Poems of Shakespeare, 251–67. Abingdon ; New York : Routledge, 2017. | Series: Longman annotated English poets: Routledge, 2017. http://dx.doi.org/10.4324/9781315707945-4.

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Nixdorff, Kathryn, Gabriele Weber, Kerstin Kaniecki, Waltraud Ruiner, and Sigrid Schell. "Bacterial Protein-LPS Complexes and Immunomodulation." In Microbial Infections, 49–61. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3434-1_6.

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Bausen, A., U. Schenk, J. Maack, and D. Nitsch. "UWB, LPM, HPM, and EMP Susceptibility of Complex PC Systems." In Ultra-Wideband, Short-Pulse Electromagnetics 7, 479–86. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-37731-5_52.

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Davendra, Donald, Roman Senkerik, Ivan Zelinka, Michal Pluhacek, and Magdalena Bialic-Davendra. "Utilising the Chaos-Induced Discrete Self Organising Migrating Algorithm to Schedule the Lot-Streaming Flowshop Scheduling Problem with Setup Time." In Nostradamus 2013: Prediction, Modeling and Analysis of Complex Systems, 31–45. Heidelberg: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-00542-3_6.

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Rohwer-Happe, Gislind. "The Mr. Darcy Complex – The Impact of a Literary Icon on Contemporary Chick Lit." In Pride and Prejudice 2.0, 207–26. Göttingen: V&R Unipress, 2015. http://dx.doi.org/10.14220/9783737004527.207.

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Tanguy, P. A., R. Lacroix, and L. Choplin. "Three-Dimensional Modeling of Rheologically Complex Fluid Flow in a LPD Dow-Ross Static Mixer." In Third European Rheology Conference and Golden Jubilee Meeting of the British Society of Rheology, 476–77. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0781-2_161.

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"lit '." In Automated Scoring of Complex Tasks in Computer-Based Testing, 139–79. Routledge, 2006. http://dx.doi.org/10.4324/9780415963572-8.

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"Chapter 6 Hierarchical LBT Decompositions." In Decentralized Control of Complex Systems, 311–73. Elsevier, 1991. http://dx.doi.org/10.1016/s0076-5392(08)63424-4.

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Abate, Marco. "Index theorems for meromorphic self-maps of the projective space." In Frontiers in Complex Dynamics, edited by Araceli Bonifant, Mikhail Lyubich, and Scott Sutherland. Princeton University Press, 2014. http://dx.doi.org/10.23943/princeton/9780691159294.003.0017.

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This chapter uses techniques from the theory of local dynamics of holomorphic germs tangent to the identity to prove three index theorems for global meromorphic maps of projective space. More precisely, the chapter seeks to prove a particular index theorem: Let f : ℙⁿ ⇢ ℙⁿ be a meromorphic self-map of degree ν‎ + 1 ≥ 2 of the complex n-dimensional projective space. Let Σ‎(f) = Fix(f) ∪ I(f) be the union of the indeterminacy set I(f) of f and the fixed points set Fix(f) of f. Let Σ‎(f) = ⊔subscript Greek Small Letter AlphaΣ‎subscript Greek Small Letter Alpha be the decomposition of Σ‎ in connected components, and denote by N the tautological line bundle of ℙⁿ. After laying out the statements under this theorem, the chapter discusses the proofs.
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Conference papers on the topic "Lpt complex"

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Sandberg, Richard D., Richard Pichler, Liwei Chen, Roderick Johnstone, and Vittorio Michelassi. "Compressible Direct Numerical Simulation of Low-Pressure Turbines: Part I — Methodology." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-25685.

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Modern low pressure turbines (LPT) feature high pressure ratios and moderate Mach and Reynolds numbers, increasing the possibility of laminar boundary-layer separation on the blades. Upstream disturbances including background turbulence and incoming wakes have a profound effect on the behavior of separation bubbles and the type/location of laminar-turbulent transition and therefore need to be considered in LPT design. URANS are often found inadequate to resolve the complex wake dynamics and impact of these environmental parameters on the boundary layers and may not drive the design to the best aerodynamic efficiency. LES can partly improve the accuracy, but has difficulties in predicting boundary layer transition and capturing the delay of laminar separation with varying inlet turbulence levels. Direct Numerical Simulation (DNS) is able to overcome these limitations but has to date been considered too computationally expensive. Here a novel compressible DNS code is presented and validated, promising to make DNS practical for LPT studies. Also, the sensitivity of wake loss coefficient with respect to freestream turbulence levels below 1% is discussed.
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Zeng, Xian, and Jiaqi Luo. "EFFECTS OF SURFACE ROUGHNESS ON FLOW LOSSES OF A HIGH-LOADING LOW-PRESSURE TURBINE CASCADE." In GPPS Xi'an21. GPPS, 2022. http://dx.doi.org/10.33737/gpps21-tc-75.

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Laminar separation induced flow transition has been regarded as one common but complex flow in low pressure turbine (LPT), which is one main source of flow losses of LPT. Lots of studies have demonstrated that the realistic rough blade of LPT favors the reduction of flow losses as the laminar separation can be delayed by increasing the roughness. Subsequently, the flow separation bubble on the suction side can be reduced, and even disappears. The present paper investigates the effects of surface roughness on flow separation of an LPT cascade, T106C. Firstly, a detailed grid-independent study assisted by Richardson extrapolation is presented to illustrate the reliability of the numerical solutions obtained by solving RANS and SST γ -Re˜θ transition model equations. Then a series of roughness with different geometric roughness height (Ra) are imposed on the whole suction side. The effects of roughness on the reduction of separation bubble are illustrated and compared. The results demonstrate that there is one critical Ra, below which the flow losses decrease, while above which the flow losses increase as Ra increases. Finally, different roughness allocations with sand grains imposed on different blade portions of the suction side are studied. Through comparisons, the sensitivities of flow loss reduction to the roughness on different blade portions are evaluated and illustrated. The study paves the way for finding an optimal roughness allocation on the suction side to minimize the flow losses.
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Praisner, T. J., E. Grover, R. Mocanu, R. Jurek, and R. Gacek. "Predictions of Unsteady Interactions Between Closely Coupled HP and LP Turbines With Co- and Counter-Rotation." In ASME Turbo Expo 2010: Power for Land, Sea, and Air. ASMEDC, 2010. http://dx.doi.org/10.1115/gt2010-23681.

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Here we report on an analytical study of the unsteady aerodynamic interactions of a closely coupled, co-rotating, high- and low-pressure turbine configuration. The effort was focused on the prediction of unsteady surface pressures imparted on the first blade of the low-pressure turbine (LPT). As a first step, a baseline three-row time-accurate prediction was carried out for the first three rows of the low-pressure turbine (vane-blade-vane). In contrast to the three-row results, a four-row analysis, which included the blade of the high-pressure turbine, revealed that the temporally varying tangential load on the LPT blade was increased in amplitude by a factor of five compared to the three-row case with a shift in primary unsteady energy to unexpected frequencies. In the four-row analysis, a region of unusually high unsteadiness near the tip of the LPT blade was also characterized by an increase in the amplitude of the fluctuating surface pressure by a factor of nearly seven, again, with unexpected attendant frequencies. A model is presented which explains the unexpected frequencies realized in the four-row results and allows the redetermination of these frequencies without the use of CFD. In an effort to better understand the complex interactions between the high- and low-pressure turbines, the first vane of the low-pressure turbine was redesigned, and the remaining airfoils were reoriented, to establish a counter-rotating turbine configuration. While substantial reductions in unsteady surface-pressure amplitudes were realized near the tip of the LPT blade with the switch to counter rotation, the amplitude of the temporally varying tangential load on the blade remained notably higher than that from the three-low analysis. The precise physical cause for the high levels of local unsteadiness near the tip of the first LPT blade in the co-rotating configuration remains unclear.
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Granovskiy, A. V., I. V. Afanasiev, V. K. Kostege, and E. Yu Marchukov. "Improving Characteristics of a Cooled Transonic Vane of Low Pressure Turbine Under Nonuniform Inlet Conditions." In ASME Turbo Expo 2020: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/gt2020-15589.

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Abstract Vanes of low-pressure turbines (LPT) run under inlet conditions generated by a preceding high-pressure turbine (HPT). HP stages are generally cooled and transonic as well due to the large pressure ratio necessary to reduce the gas temperature upstream of the downstream stages. Therefore radial distributions of inlet flow angle, total pressure and total temperature at the boundary upstream of the LPT are highly non–uniform. Such non-uniform inlet conditions can result in enhanced level of the total losses including the secondary losses. Moreover, vanes of LPT have meridional openings along inner and outer boundaries of the flow path, which causes intensification of the secondary flows leading to an increase in secondary losses. In this case the special meridional contouring of the vanes’ outer and inner surfaces allows a decrease in the flare angle namely meridional opening in the rear part of the vane. In this work, in order to compensate the negative effect of non-uniform inlet conditions, meridional opening and low aspect ratio, 3D profiling of the vane row is used as a way of reducing secondary losses. Some variants of LPT vanes with various complex 3D shapes are investigated. In particular, vane variants with a “reversed bow”, a “bowed” and a “lean” in the circumferential direction have been examined. Significant modification of the vane row is limited by cooling system design, which has to incorporate a deflector in the inner hollow of the vane to improve cooling effectiveness. A compromise between aerodynamic quality and cooling limitations has been achieved.
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Keadle, Kevin, and Mark McQuilling. "Evaluation of RANS Transition Modeling for High Lift LPT Flows at Low Reynolds Number." In ASME Turbo Expo 2013: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/gt2013-95069.

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High lift low pressure turbine airfoils have complex flow features that can require advanced modeling capabilities for accurate flow predictions. These features include separated flows and the transition from laminar to turbulent boundary layers. Recent applications of computational fluid dynamics based on the Reynolds-averaged Navier-Stokes formulation have included modeling for attached and separated flow transition mechanisms in the form of empirical correlations and two- or three-equation eddy viscosity models. This study uses the three-equation model of Walters and Cokljat [1] to simulate the flow around the Pack B and L2F low pressure turbine airfoils in a two-dimensional cascade arrangement at a Reynolds number of 25,000. This model includes a third equation for the development of pre-transitional laminar kinetic energy (LKE), and is an updated version of the Walters and Leylek [2] model. The aft-loaded Pack B has a nominal Zweifel loading coefficient of 1.13, and the front-loaded L2F has a nominal loading coefficient of 1.59. Results show the updated LKE model improves predicted accuracy of pressure coefficient and velocity profiles over its previous version as well as two-equation RANS models developed for separated and transitional flows. Transition onset behavior also compares favorably with experiment. However, the current model is not found suitable for wake total pressure loss predictions in two-dimensional simulations at extremely low Reynolds numbers due to the predicted coherency of suction side vortices generated in the separated shear layers which cause a local gain in wake total pressure.
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Bernardini, Chiara, Craig Sacco, Jeffrey P. Bons, Jen-Ping Chen, and Francesco Martelli. "The Role of Three-Dimensional Interactions in Fluidic Control of Shock-Induced Separation on a Transonic Turbine Blade." In ASME Turbo Expo 2015: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/gt2015-43395.

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An experimental and numerical investigation is conducted to assess the fluid dynamic mechanisms of control by vortex-generator jets for shock-induced separation in a highly loaded low pressure turbine (LPT) blade. Two- and three-dimensional steady RANS computations are performed to evaluate their ability to reproduce the main features of such a complex flow. The test blade is part of a compressible LPT cascade that exhibits shock-induced separation at an exit Mach number of 0.8. Active flow control is implemented through a spanwise row of discrete vortex-generator jets (VGJs) located on the suction surface. The control performance of VGJs in these transonic conditions has an optimum blowing ratio beyond which losses increase. Three-dimensionalities in the flow field are established by discrete VGJ-boundary layer interaction as suggested by Particle-Image Velocimetry (PIV) acquisitions at different spanwise locations. Blade pressure distributions and wake total pressure losses are acquired to evaluate the control performance and compared with calculations. Two-dimensional numerical investigations by RANS simulations suggest that the effect of increased expansion over the passage is a product of massflow injection only. Three-dimensional RANS results are interrogated to give a more detailed representation of the flow features around the jets, such as the jet vortex dynamics and spanwise modulation of the potential field. The analysis of this experimental and numerical information identifies the mechanisms contributing to the performance of skewed jets for control of shock induced separation in a highly loaded LPT blade. The results provide indications on the accuracy of RANS simulations, identifying the challenges of using RANS (2D or 3D) to solve such complex flows.
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Lomario, D., G. P. De Poli, L. Fattore, and J. Marczyk. "A Complexity-Based Approach to Robust Design and Structural Assessment of Aero Engine Components." In ASME Turbo Expo 2007: Power for Land, Sea, and Air. ASMEDC, 2007. http://dx.doi.org/10.1115/gt2007-27205.

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This paper presents a complexity-based methodology for the design of aero engine components. Upon a rigorous definition of complex system, a metric for the complexity is introduced as a function of system’s topology and entropy. As a consequence, complexity becomes a measurable and manageable property of systems. Furthermore, a novel definition of robustness is provided, based on the shape of the probability density functions (PDF) of the performances. Complexity and robustness are related together by a simple, qualitative law. Based on these premises, two algorithms are introduced, namely the Stochastic Design Improvement (SDI) and the Complex Systems Analyzer (CSA). The former searches the design space seeking for solutions which meet the design requirements. The latter extracts the fundamental features of the design, previously perturbed by means of Monte Carlo Simulation (MCS). The SDI is proposed as a competitor of the practice of optimization. Though both can be used separately, the combination of SDI and CSA provides a powerful novel method for design. The capabilities of the algorithms are illustrated on three test-cases, namely an LPT Casing, a Turbo-prop bearing retainer and an LPT disk. It is important to point out that response surfaces or other surrogates have never been used.
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Gao, Jie, Xuezheng Liu, Weiyan Xiao, Weiliang Fu, Fusheng Meng, Guoqiang Yue, and Qun Zheng. "Numerical Simulation of ITD Flows in the Presence of HP Blade and LP Vane." In ASME Turbo Expo 2018: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/gt2018-75516.

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Flows in an intermediate turbine duct (ITD) connecting high-pressure turbines (HPT) and low-pressure turbines (LPT) are highly complex, influenced by the upstream HP turbine flow structures. Non-uniformities originating from the duct with struts of different sizes also affect the LPT inflow conditions, resulting in reduced efficiency. The goal of this paper is to provide detailed understanding of the flow physics and loss mechanisms within the ITDs for highly efficient ITD designs. Steady and unsteady numerical simulations of flows through the ITDs in the presence of HP blade and LP vane were conducted. Effects of upstream HP blade on flow fields and loss characteristics within the ITDs are explored. The generation and propagation of wake and secondary flows through the whole configuration is described, including the fast Fourier transformation (FFT) analyses of the flow in the ITD. Results from the numerical simulations show complex flow patterns resulted from blade-strut-vane flow interactions in a high-endwall-angle duct, which are not obtainable from ITD-only simulations. Moreover, the ITD has a strong amplifying effect on the distorted inflow, and the inflow with the upstream wake and secondary flows introduces a high loss area along the casing at ITD exit. Detailed results are presented and discussed for the flow physics and loss mechanisms within the ITD.
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Pramstrahler, Simon, Andreas Peters, Mikel Lucas García De Albéniz, Peter Adrian Leitl, Franz Heitmeir, and Andreas Marn. "The Impact of Inlet Flow Angle on Turbine Vane Frame Aerodynamic Performance." In ASME Turbo Expo 2022: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/gt2022-78065.

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Abstract Modern aero-engines are designed for high efficiency and low weight to reduce fuel consumption and achieve reductions in CO2 emissions. According to the goals and roadmap of the “Flightpath 2050” report, the Strategic Research and Innovation Agenda (SRIA) demands a drastic reduction of emissions to balance further air traffic growth. Therefore, technologies and processes allowing for a 75 % reduction in CO2 emissions per passenger kilometer compared to the year 2000 technology standard must be available by 2050. Turbine Vane Frames (TVF) are one technology to increase the efficiency of aero-engines and can therefore help to reach this goal. Turbine Vane Frames are located in-between the high-pressure turbine (HPT) and the low-pressure turbine (LPT) of an aero-engine and have three major purposes: guiding the flow to higher radii, incorporating the function of stator guide vanes of the first stage of the LPT, and passing structural components and oil pipes through the flow channel. A TVF with aft-loaded wide-chord main vanes and splitter vanes was designed, which meets engine-representative mechanical and aerodynamic constraints. A test vehicle consisting of the TVF and a first-stage LPT rotor has been designed and is currently being tested in the subsonic test turbine facility for aerodynamic, aeroacoustic and aeroelastic investigations (STTF-AAAI) at the Graz University of Technology. In the engine, the TVF needs to function at high performance not only at the aerodynamic design point (cruise) but also at off-design conditions. A splittered TVF design features complex flow fields with strong secondary flow interactions, and because of the fundamental design differences, the flow field characteristics within a TVF are different from those in a conventional LPT vane row. This paper discusses the flow field in a splittered TVF with emphasis on secondary flow structures and their interaction with each other and the main flow. To examine the influence of different swirl angle levels on the flow field and loss generation mechanisms inside the TVF, the swirl angle upstream of the TVF is numerically changed in a wide range from positive to negative angles. The objective of this study is to examine the sensitivity of the splitter vanes to large flow angle deviations, as present in part-load operation. Additionally, the flow field downstream of the TVF and its influence on the LPT rotor performance is described in detail. The size and locations of separated flow regions resulting from the off-design incidence of the flow and their impact on the rotor are investigated and quantified. A loss breakdown is presented to discuss the impact of incidence variations on the performance of both the TVF and the LPT.
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Magerramova, Liubov, Boris Vasilyev, and Vladimir Kinzburskiy. "Novel Designs of Turbine Blades for Additive Manufacturing." In ASME Turbo Expo 2016: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/gt2016-56084.

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Improving engine performance requires creating new materials and improving design and manufacturing. Additive Manufacturing (AM) is advancing rapidly and allows us to produce details of complex shapes that cannot be produced by traditional methods. The goal of this study was to demonstrate the possibility of using AM for the manufacture of turbine blades with a complex geometry, including those with advanced cooling systems, which cannot be manufactured by conventional methods. This paper presents the results of the design and calculations of high-pressure turbine (HPT) cooled blades, as well as a low-pressure turbine (LPT) uncooled blade that was designed using topology optimization (TO). Several blades were manufactured using AM. 3D tomography test results for those blades confirm the possibility of AM application in production of blades with complex geometry.
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Reports on the topic "Lpt complex"

1

Luc, Brunet. Systematic Equations Handbook : Book 1-Energy. R&D Médiation, May 2015. http://dx.doi.org/10.17601/rd_mediation2015:1.

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The energy equation handbook is the complete collection of physically coherent expression of energy computed using from 2 to 7 physical units among: density(ML-3) energy (ML2T-2) time (T) force (MLT-2) power (ML2T-3) current (I) temperature (Th) quantity (N) mass (M) length (L) candela (J) surface (L2) volume (L3) concentration (ML-3) frequency (T-1) acceleration (LT- 2) speed (LT-1) pressure (ML-1T-2) viscosity (ML-1T-1) luminance (L- 2J) MolarMass (MN-1) MassicEnergy (L2T-2) resistance (ML2T-3I-2) voltage (ML2T-3I-1) Farad (M-1L-2T4I2) Thermal- Conductivity (MLT-3Th-1) SpecificHeat (L2T-2Th-1) MassFlux (MT-1) SurfaceTension (MT-2) Charge (TI) Resistivity (ML3T-3I-2) The complete list of 4196 equations is sorted by number of variable required to obtain an energy in Joules. All the units are in MKSA.
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Andrews, Matt. Getting Real about Unknowns in Complex Policy Work. Research on Improving Systems of Education (RISE), November 2021. http://dx.doi.org/10.35489/bsg-rise-wp_2021/083.

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As with all public policy work, education policies are demanding. Policy workers need to ‘know’ a lot—about the problems they are addressing, the people who need to be engaged, the promises they can make in response, the context they are working in, and the processes they will follow to implement. Most policy workers answer questions about such issues within the structures of plan and control processes used to devise budgets and projects. These structures limit their knowledge gathering, organization and sense-making activities to up-front planning activities, and even though sophisticated tools like Theories of Change suggest planners ‘know’ all that is needed for policy success, they often do not. Policies are often fraught with ‘unknowns’ that cannot be captured in passive planning processes and thus repeatedly undermine even the best laid plans. Through a novel strategy that asks how much one knows about the answers to 25 essential policy questions, and an application to recent education policy interventions in Mozambique, this paper shows that it is possible to get real about unknowns in policy work. Just recognizing these unknowns exist—and understanding why they do and what kind of challenge they pose to policy workers—can help promote a more modest and realistic approach to doing complex policy work.
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Rizzo, Tesalia. Shaping political trust through participatory governance in Lat in America. Inter-American Development Bank, August 2021. http://dx.doi.org/10.18235/0003601.

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This paper critically assesses research that examines the link between participatory institutions and political trust in the context of developing countries, with a focus on Latin America. A significant limitation in the systematic accumulation of knowledge in this field is inattention to identifying a clear causal chain through which citizen participation shapes political, economic, and attitudinal outcomes such as political trust. This is particularly important in the Latin American case where constitutionally stated objectives of participatory governance include the improvement of citizen welfare as well as strengthening of political trust in public institutions. Future work should concentrate in providing clear and testable models of the complex relationship between participatory mechanisms, policy, governance, and trust, with particular attention to what mediates and moderates this relationship. Additionally, empirical work done of the Latin America case should move away from a predominantly case-study based and macro-level perspective in the study of participatory institutions to micro-level studies from the citizens point of view. A new frontier for the study of participatory governance in Latin America lies in understanding how citizens experiences with and expectations of participatory institutions as well as the policy outcomes delivered by these institutions shape political trust.
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Peek, Dennis W. Environmental Baseline Survey for Proposed Land Use Permit Modification for Expansion of the Dynamic Explosive Test Site (DETS) 9940 Main Complex Parking Lot. Office of Scientific and Technical Information (OSTI), February 2016. http://dx.doi.org/10.2172/1239347.

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Peek, Dennis W. Supplemental Environmental Baseline Survey for Proposed Land Use Permit Modification for Expansion of the Dynamic Explosive Test Site (DETS) 9940 Main Complex Parking Lot. Office of Scientific and Technical Information (OSTI), October 2016. http://dx.doi.org/10.2172/1331359.

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Peek, Dennis W. Supplemental Environmental Baseline Survey for Proposed Land Use Permit Modification for Expansion of the Dynamic Explosive Test Site (DETS) 9940 Main Complex Parking Lot. Office of Scientific and Technical Information (OSTI), October 2017. http://dx.doi.org/10.2172/1528764.

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Dixon, David A., and Henry Grady Hughes. A Complete Reporting of MCNP6 Validation Results for Electron Energy Deposition in Single-Layer Extended Media for Source Energies <= 1-MeV. Office of Scientific and Technical Information (OSTI), May 2016. http://dx.doi.org/10.2172/1253497.

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Weller, Joel I., Derek M. Bickhart, Micha Ron, Eyal Seroussi, George Liu, and George R. Wiggans. Determination of actual polymorphisms responsible for economic trait variation in dairy cattle. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600017.bard.

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The project’s general objectives were to determine specific polymorphisms at the DNA level responsible for observed quantitative trait loci (QTLs) and to estimate their effects, frequencies, and selection potential in the Holstein dairy cattle breed. The specific objectives were to (1) localize the causative polymorphisms to small chromosomal segments based on analysis of 52 U.S. Holstein bulls each with at least 100 sons with high-reliability genetic evaluations using the a posteriori granddaughter design; (2) sequence the complete genomes of at least 40 of those bulls to 20 coverage; (3) determine causative polymorphisms based on concordance between the bulls’ genotypes for specific polymorphisms and their status for a QTL; (4) validate putative quantitative trait variants by genotyping a sample of Israeli Holstein cows; and (5) perform gene expression analysis using statistical methodologies, including determination of signatures of selection, based on somatic cells of cows that are homozygous for contrasting quantitative trait variants; and (6) analyze genes with putative quantitative trait variants using data mining techniques. Current methods for genomic evaluation are based on population-wide linkage disequilibrium between markers and actual alleles that affect traits of interest. Those methods have approximately doubled the rate of genetic gain for most traits in the U.S. Holstein population. With determination of causative polymorphisms, increasing the accuracy of genomic evaluations should be possible by including those genotypes as fixed effects in the analysis models. Determination of causative polymorphisms should also yield useful information on gene function and genetic architecture of complex traits. Concordance between QTL genotype as determined by the a posteriori granddaughter design and marker genotype was determined for 30 trait-by-chromosomal segment effects that are segregating in the U.S. Holstein population; a probability of <10²⁰ was used to accept the null hypothesis that no segregating gene within the chromosomal segment was affecting the trait. Genotypes for 83 grandsires and 17,217 sons were determined by either complete sequence or imputation for 3,148,506 polymorphisms across the entire genome. Variant sites were identified from previous studies (such as the 1000 Bull Genomes Project) and from DNA sequencing of bulls unique to this project, which is one of the largest marker variant surveys conducted for the Holstein breed of cattle. Effects for stature on chromosome 11, daughter pregnancy rate on chromosome 18, and protein percentage on chromosome 20 met 3 criteria: (1) complete or nearly complete concordance, (2) nominal significance of the polymorphism effect after correction for all other polymorphisms, and (3) marker coefficient of determination >40% of total multiple-regression coefficient of determination for the 30 polymorphisms with highest concordance. The missense polymorphism Phe279Tyr in GHR at 31,909,478 base pairs on chromosome 20 was confirmed as the causative mutation for fat and protein concentration. For effect on fat percentage, 12 additional missensepolymorphisms on chromosome 14 were found that had nearly complete concordance with the suggested causative polymorphism (missense mutation Ala232Glu in DGAT1). The markers used in routine U.S. genomic evaluations were increased from 60,000 to 80,000 by adding markers for known QTLs and markers detected in BARD and other research projects. Objectives 1 and 2 were completely accomplished, and objective 3 was partially accomplished. Because no new clear-cut causative polymorphisms were discovered, objectives 4 through 6 were not completed.
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Quintero Ramírez, Nini, Yuris Sánchez García, Yasmina Toncel, and Liliana Reales Hernández. Estimulación táctil kinestésica: abordaje desde enfermería. Ediciones Universidad Cooperativa de Colombia, August 2021. http://dx.doi.org/10.16925/gcnc.17.

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La supervivencia de neonatos que no cumplen su desarrollo gestacional completo (< 34 semanas) se ve sometida a técnicas que estimulan su desarrollo neuronal. Por lo tanto, se da a conocer la técnica de estimulación táctil kinestésica, que consiste en desarrollar los estímulos sensoriales del neonato; así mismo, se describe cómo llevar a cabo ese proceso y el aprendizaje adquirido por los neonatos. El presente documento hace un abordaje grosso modo de la técnica de estimulación táctil kinestésica de acuerdo con algunos autores que han investigado acerca de la temática.
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ADA JOINT PROGRAM OFFICE ARLINGTON VA. Ada Compiler Validation Summary Report: Certificate Number: 910612W1. 11168 Telesoft, IBM Ada/370, Version 1.2.0 (without Optimization) IBM 3080, V</ SP HPO Rel 5.0 (Unopt) (Host & Target). Fort Belvoir, VA: Defense Technical Information Center, June 1991. http://dx.doi.org/10.21236/ada246532.

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