Journal articles on the topic 'Loss of enjoyment of life'

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1

McDonald, M. Brian. "Loss of Enjoyment of Life Damages in New Mexico." Journal of Forensic Economics 20, no. 2 (January 1, 2008): 171–86. http://dx.doi.org/10.5085/0898-5510-20.2.171.

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Novielli, Robert, and Brian H. Kleiner. "How to compute the loss of enjoyment of life." Management Research News 26, no. 10/11 (December 10, 2003): 105–14. http://dx.doi.org/10.1108/01409170310784104.

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Fjaeldstad, Alexander Wieck, and Barry Smith. "The Effects of Olfactory Loss and Parosmia on Food and Cooking Habits, Sensory Awareness, and Quality of Life—A Possible Avenue for Regaining Enjoyment of Food." Foods 11, no. 12 (June 8, 2022): 1686. http://dx.doi.org/10.3390/foods11121686.

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Olfactory dysfunction often has severe consequences on patients’ quality of life. The most common complaint in these patients is their reduced enjoyment of food in both patients with olfactory loss and parosmia. How the different types of olfactory dysfunction differ in relation to food and cooking habits, sensory awareness, and food-related quality of life has not yet received much attention. By applying questionnaires on cooking, food, olfactory function, weight changes, sensory awareness, and food-related quality of life, we investigated how various aspects of eating differ between participants with olfactory loss (n = 271), parosmia (n = 251), and normosmic controls (n = 166). Cooking habits in olfactory dysfunction revealed pronounced differences as compared with normosmic controls. Cooking with olfactory dysfunction was associated with, e.g., a lack of comfort and inspiration for cooking and an inability to make new foods successfully. Significant differences in cooking were also found between olfactory loss and parosmia. Food items were less familiar in participants with olfactory loss and parosmia, while the ratings of liking food items differed between olfactory loss and parosmia, indicating the importance of adapting ingredients in meals separately for olfactory loss and parosmia. Parosmia was associated with a higher incidence of weight loss, but we found no difference in food-related quality of life between participants with olfactory loss and parosmia. While olfactory loss and parosmia have wide-ranging consequences on patients’ cooking and food habits, adapting meals to include ‘safer food items’ and integrating multisensory stimulation may be a possible avenue for improving the enjoyment of food.
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Gad, Dustin, Amanda Piechota, and Joan Monin. "POSITIVE EMOTION EXPRESSION AND ADAPTIVE COPING BEHAVIORS FOR ADULT CHILDREN OF PARENTS WITH MEMORY LOSS." Innovation in Aging 6, Supplement_1 (November 1, 2022): 772. http://dx.doi.org/10.1093/geroni/igac059.2796.

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Abstract The broaden-and-build theory suggests that experiences of positive emotion may lead to enhanced utilization of adaptive coping strategies, and a decrease in maladaptive coping strategies (Gloria & Steinhardt, 2016). This relationship between positive emotion and adaptive coping has yet to be studied directly in a sample of adult child caregivers of a parent with memory loss. As part of a larger study investigating relationship dynamics between adult children and their parents with memory loss, adult children 18 years of age and older (n= 67) responded to self-report surveys and engaged in a 6 minute, video recorded, positive interaction session, playing “name that tune” with each other. The session was observationally coded by two coders for “enjoyment/enthusiasm/fun” (k= .516), “laughter” (k= .631), and “positive affect displayed towards partner” (k=.464), using a reliable and valid support-seeking and caregiving behavior coding system (Collins & Feeney, 2000). Spearman’s rank correlations between these behavior codes and the self-reported Brief COPE Inventory (BCI) scores suggested positive correlations between “laughter” and the emotional support subscale of the BCI (rs=.259, p= .034), and between “positive affect displayed towards partner” and the venting subscale of the BCI (rs= .256, p= .036). These findings suggest that the expression of positive emotions in the caregiving process might yield important psychological benefits to the caregiver, through increased utilization of specific coping mechanisms. More research in this area is needed to determine whether positive emotion expression is associated with the use of adaptive coping more so than maladaptive coping mechanisms in this population.
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Hättich, Achim, and Martina Schweizer. "I hear what you see: Effects of audio description used in a cinema on immersion and enjoyment in blind and visually impaired people." British Journal of Visual Impairment 38, no. 3 (March 23, 2020): 284–98. http://dx.doi.org/10.1177/0264619620911429.

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For people with disabilities being part of social life is essential for well-being. To accomplish this there are two possibilities: through interaction in person and through access to culture. One way to enjoy both possibilities is the cinema. For people with sight loss (people that are blind or visually impaired), there exists audio description which allows enjoying a film in a cinema. Project FASEA examined if this audience is as much immersed and could enjoy it as much as sighted people while watching a film with audio description, received through an app called ‘Greta’. Twenty-five people with blindness or visual impairment took part and were matched with sighted people in age, sex, education, and nationality. This was conducted in a commercial cinema under natural conditions with a comedy. We assessed immersion through the Narrative Engagement Scale (NES), the Modes of Reception Inventory (MOR), and the Audience Response Scale (ARS). Enjoyment was evaluated with the Emotions in Media Scale (EMS). People with sight loss showed lower scores in narrative understanding in NES and less thought-provoking and suspense in ARS. Also, they experienced fewer positive emotions. In all other scales, including all MOR scales, there were no differences between them and sighted people. The results confirm that audio description, provided by an application, is a useful tool for people with sight loss to immerse themselves and enjoy films as much as sighted people do and hence be part of social life.
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Frewen, Sharon, Helgo Schomer, and Tim Dunne. "Health Belief Model Interpretation of Compliance Factors in a Weight Loss and Cardiac Rehabilitation Programme." South African Journal of Psychology 24, no. 1 (March 1994): 39–43. http://dx.doi.org/10.1177/008124639402400106.

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The aim of the research was to establish the common and/or different factors associated with compliance or noncompliance in either a weight loss or a cardiac rehabilitation programme. A questionnaire was designed from a revised formulation of the original Health Belief Model and a pilot study was run on 22 weight loss and 13 cardiac subjects. The modified questionnaire was then completed by 37 compliers and 19 noncompliers with a weight loss programme and 11 compliers and 19 noncompliers with a cardiac rehabilitation programme. Compliance was associated with exercise enjoyment, self-motivation, and the need to stay on the programme. The major reasons for noncompliance were the complexity of the required behaviour changes, inconvenience, time constraints, and the ability to cope independently of the programmes. Particularly regarding the weight loss programme, noncompliance arising from the required simultaneous changes to eating and exercise patterns could be reduced by teaching alternative coping skills and realistic goal setting. Cardiac patients are faced with the life-threatening nature of their disease, but there is a lack of overt disease symptoms among weight loss subjects. This results in a need to inform obese subjects, preferably using a multi-disciplinary approach, about the health risks resulting from noncompliance.
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Babarykina, Nadiia. "Crisis del modelo democrático en el siglo XXI." Cuestiones Políticas 40, no. 72 (March 7, 2022): 16–20. http://dx.doi.org/10.46398/cuestpol.4072.00.

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The objective of the text is to serve as an editorial to the edition volume 40, number 72, January-June 2022 of Political Issues. Methodologically, it is an editorial essay of a reflective nature based on documentary sources consulted in digital format. The crisis of the democratic model is in some way a global phenomenon that affects, to a greater or lesser extent, all modern societies that have adopted the government of the people and the power of the people as a form of state and government with constitutional status. It is concluded that democracy, beyond its different expressions and modalities, is the only political system that allows the enjoyment and enjoyment of human rights in a social framework of freedom, quality of life and dignity, but despite its benefits it is not exempt from contradictions such as: the crisis of representation, the loss of confidence in political institutions and the corruption of political parties and their respective leaderships; these contradictions put at stake the legitimacy of this form of government and also create the conditions of possibility for the production of neo-populist or neoconservative leadership that vindicate authoritarian ways of exercising power to the detriment of the rule of law.
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Telles, Shirley, Sachin Kumar Sharma, Alok Singh, Niranjan Kala, Vikas Upadhyay, Jaideep Arya, and Acharya Balkrishna. "Quality of Life in Yoga Experienced and Yoga Naïve Asian Indian Adults with Obesity." Journal of Obesity 2019 (April 30, 2019): 1–7. http://dx.doi.org/10.1155/2019/9895074.

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Background. Obesity adversely affects quality of life which then acts as a barrier to weight loss and weight loss maintenance. Hence, those interventions which positively influence the quality of life along with weight reduction are considered useful for sustained weight loss in persons with obesity. An earlier study showed better quality of life in obese adults who had experience of yoga compared to yoga naïve obese adults. However, the main limitation of the study was the small sample size (n=20 in each group). Objective. The present study aimed to determine whether with larger sample sizes the quality of life would differ in yoga experienced compared to yoga naïve adults with obesity. Methods. There were 596 Asian Indian obese adults (age range 20 to 59 years; group mean age ± SD; 43.9 ± 9.9 years): of whom (i) 298 were yoga experienced (154 females; group mean age ± SD; 44.0 ± 9.8 years) with a minimum of 1 month of experience in yoga practice and (ii) 298 were yoga naïve (154 females; group mean age ± SD; 43.8 ± 10.0 years). All the participants were assessed for quality of life using the Moorehead–Ardelt quality of life questionnaire II. Data were drawn from a larger nationwide trial which assessed the effects of yoga compared to nutritional advice on obesity over a one-year follow-up period (CTRI/2018/05/014077). Results. There were higher participant-reported outcomes for four out of six aspects of quality of life in the yoga experienced compared to the yoga naïve (p<0.008, based on t values of the least squares linear regression analyses, Bonferroni adjusted, and adjusted for age, gender, and BMI as covariates). These were enjoyment in physical activities, ability to work, self-esteem, and social satisfaction. Conclusion. Obese adults with yoga experience appear to have better quality of life in specific aspects, compared to yoga naïve persons with a comparable degree of obesity.
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Chouchane, A., I. Kacem, I. Bannour, M. Kahloul, M. Maoua, W. Naija, and N. Mrizak. "Quality of Life Among Women With Breast Cancer." European Psychiatry 65, S1 (June 2022): S853. http://dx.doi.org/10.1192/j.eurpsy.2022.2209.

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Introduction Breast cancer (BC) is the most common cancer in women all over the world. Its physical consequences and psychosocial distress had adverse effect on quality of life (QOL). Objectives Evaluate the QOL among women with BC. Methods Descriptive cross-sectional study of BC patients, carried out during a period of 5 years. Socio-demographic and medical data was collected based on a pre-established synoptic sheet. The European Organization for Research and Treatment Quality of Life Questionnaires (EORTC QLQ-C30) and EORTC QLQ-BR23 were used to assess the QOL. Results A total of 100 patients were included. The mean age was 52 ± 8 years. The mean overall health score was 77.5 ± 25.5. The mean scores of physical and emotional functioning were 82 ± 25.1 and 90 ± 19.5 respectively. The QLQ-BR23 objectified a body image score of 63 ± 23.9, an average score for sexual functioning of 87.3 ± 22 with loss of sexual enjoyment in 75% of cases. The increase in mean overall health score and physical functioning was significantly associated with type of treatment (p = 0.01). The mean score of emotional functioning was correlated with the feeling of support (p = 0.04). The increase in the patient’s body image score was significantly associated with age (p <10-3), marital status (p = 0.01) and having had a mastectomy (p <10-3). Conclusions Our results underline the importance of psychosocial care, which must be an integral part of oncological care in women with BC, in order to improve their quality of life. Disclosure No significant relationships.
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Cutler, Liz, Bronwen King, Nicky McCarthy, Greg Hamilton, and Lynley Cook. "Appetite for life: an evaluation of a primary care lifestyle programme." Journal of Primary Health Care 2, no. 4 (2010): 281. http://dx.doi.org/10.1071/hc10281.

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INTRODUCTION: Appetite for Life is a six-week primary care–based programme for women who are overweight, and aims to achieve long-term health gain through establishing healthy eating and physical activity patterns and a healthier weight. AIM: To evaluate the outcomes of Appetite for Life, a primary care–based healthy lifestyle programme for women who are overweight. METHODS: Two hundred and sixty-one women enrolled and consented to take part in the six-week Appetite for Life programme via general practice and were followed for 12 months. Eating behaviours and physical activity levels were measured at baseline, six weeks, six months and 12 months. Anthropometric and biomedical data was collected at visits to the participants’ general practitioners at baseline and 12 months. RESULTS: Positive lifestyle changes were reported that were sustained for the duration of the 12-month follow-up period. Participants reported an increase in intake of fruit and vegetables, dairy products, healthy fats and an increased level of physical activity. There was also an increase in reported enjoyment and participation in exercise. Mean weight was maintained over this time period. There was a reduction in mean LDL and total plasma cholesterol. DISCUSSION: A healthy lifestyle programme offered through primary care that is based on a non-dieting approach may help overweight women develop and sustain positive lifestyle changes. KEYWORDS: Health promotion; health status; obesity; weight loss, physical activity
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Pope, Lizzy, Jean Harvey-Berino, Patrick Savage, Janice Bunn, Maryann Ludlow, Neil Oldridge, and Phil Ades. "The Impact of High-Calorie-Expenditure Exercise on Quality of Life in Older Adults With Coronary Heart Disease." Journal of Aging and Physical Activity 19, no. 2 (April 2011): 99–116. http://dx.doi.org/10.1123/japa.19.2.99.

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The acceptability of a high-calorie-expenditure (HCE) exercise program in older coronary heart disease patients participating in a behavioral weight-control program was evaluated. Seventy-four overweight patients (median age 63 yr) were randomly assigned to a 5-mo intervention of HCE exercise (3,000–3,500 kcal/wk daily walking) or standard cardiac-rehabilitation (CR) exercise (700–800 kcal/wk). Both groups received counseling to achieve a dietary caloric deficit of 3,500 kcal/ wk. Assessments at baseline and 5 mo included self-reported measures of quality of life and psychosocial variables. The HCE group experienced significantly greater weight loss (8.2 ± 4 vs. 3.7 ± 5 kg,p< .001). Changes from baseline to 5 mo on scores of physical, emotional, and social functioning were greater for the HCE than CR group (p< .05). HCE exercise also resulted in greater positive change in exercise enjoyment (p= .05), which was mediated by weight change. Even high-risk older adults can be successful in an HCE exercise program and experience no adverse physical or emotional changes.
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Patskanick, Taylor, Julie Miller, Lucas Yoquinto, Lisa D'Ambrosio, and Joseph Coughlin. "Lessons on Learning in Later Life With the MIT AgeLab 85+ Lifestyle Leaders." Innovation in Aging 5, Supplement_1 (December 1, 2021): 189. http://dx.doi.org/10.1093/geroni/igab046.722.

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Abstract Previous research has established the role of lifelong learning in promoting psychological wellbeing and active aging. Population aging necessitates an understanding of the unique opportunities and challenges around formal and informal learning in later life. This paper will share findings from a mixed methods study with the MIT AgeLab 85+ Lifestyle Leaders, a panel comprised of octogenarians and nonagenarians from across the United States. Drawing on an online survey and virtual focus groups with 29 Lifestyle Leaders from January 2021, findings suggest the Lifestyle Leaders most often learned new things from talking with others (46%) and reading print (54%) or online (54%) sources. The majority were familiar with attending in-person lectures or classes (89.7%) and were now using videoconferencing to do these (78.6%). A majority (56.7%) had or are currently participating in a lifelong learning program. Most consider themselves lifelong learners and described this around remaining curious and engaged with life, choices around what one learns, and greater enjoyment of learning. In the survey, a plurality of Lifestyle Leaders indicated the top two challenges affecting their ability to learn were sensory burdens (e.g., hearing loss, declining eyesight) (35%) and their energy level (32.4%); focus group data revealed that recall also is a barrier. Focus group data further highlighted generational experiences around early life learning and career paths, specifically how gender roles, diagnoses of learning disabilities, and evolving digital technology have affected these and changed over the course of their lifetimes.
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Patskanick, Taylor, Julie Miller, Lucas Yoquinto, Lisa D'Ambrosio, and Joseph Coughlin. "LESSONS ON LEARNING IN LATER LIFE WITH THE MIT AGELAB 85+ LIFESTYLE LEADERS." Innovation in Aging 6, Supplement_1 (November 1, 2022): 222. http://dx.doi.org/10.1093/geroni/igac059.882.

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Abstract Previous research has established the role of lifelong learning in promoting psychological wellbeing and active aging. Population aging necessitates an understanding of the unique opportunities and challenges around formal and informal learning in later life. This paper will share findings from a mixed methods study with the MIT AgeLab 85+ Lifestyle Leaders, a panel comprised of octogenarians and nonagenarians from across the United States. Drawing on an online survey and virtual focus groups with 29 Lifestyle Leaders from January 2021, findings suggest the Lifestyle Leaders most often learned new things from talking with others (46%) and reading print (54%) or online (54%) sources. The majority were familiar with attending in-person lectures or classes (89.7%) and were now using videoconferencing to do these (78.6%). A majority (56.7%) had or are currently participating in a lifelong learning program. Most consider themselves lifelong learners and described this around remaining curious and engaged with life, choices around what one learns, and greater enjoyment of learning. In the survey, a plurality of Lifestyle Leaders indicated the top two challenges affecting their ability to learn were sensory burdens (e.g., hearing loss, declining eyesight) (35%) and their energy level (32.4%); focus group data revealed that recall also is a barrier. Focus group data further highlighted generational experiences around early life learning and career paths, specifically how gender roles, diagnoses of learning disabilities, and evolving digital technology have affected these and changed over the course of their lifetimes.
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Nguyen, Lydia, Karen O'Hern, Adam Siak, Kristi Stoglin, and Charlotte Mather-Tayor. "Impact of iN2L Tablets on Loneliness and Well-Being: Findings of an Innovative Industry-AAA Program." Innovation in Aging 5, Supplement_1 (December 1, 2021): 942. http://dx.doi.org/10.1093/geroni/igab046.3404.

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Abstract Area Agency on Aging (AAA) senior and adult day centers closed due to COVID-19, causing many older adults to lose an important source of connection and engagement, leading to social isolation. To combat negative consequences, iN2L and a Florida AAA partnered on an innovative program providing iN2L tablets to AAA-supported older adults to use at home. The tablets have a simple interface, content specifically designed for older adults (e.g., games; music; movies), and video call capability. Participants included 51 independent older adults (mean age 77) and 39 family caregivers (mean age 59) of people with dementia. Participants completed phone surveys with AAA case managers at baseline and 3 months, including UCLA Loneliness Scale (3 item) and questions about their tablet experiences. Findings show positive trends for loneliness and well-being in both groups. At 3 months, lonely participants decreased from baseline by 25% for independent older adults and 18% for family caregivers. Over 80% of independent older adults agreed the tablet engages them in meaningful activities, provides daily enjoyment, and helps with relaxation. For family caregivers, 79% agreed the tablet is another tool in their caregiver toolkit and about 70% agreed the tablet adds daily enjoyment, helps with relaxation, and provides engagement in meaningful activities for their family member. Approximately 50% of caregivers felt happier, less stressed, and less irritable since using the tablets. This work has implications for the utility of technology in promoting engagement and connection, alleviating negative effects of social isolation, and the effectiveness of industry-AAA partnerships.
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Phoosuwan, Nitikorn, and Pranee C. Lundberg. "Psychological distress and health-related quality of life among women with breast cancer: a descriptive cross-sectional study." Supportive Care in Cancer 30, no. 4 (December 23, 2021): 3177–86. http://dx.doi.org/10.1007/s00520-021-06763-z.

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Abstract Purpose Breast cancer is the most common type of cancer found in women in Sweden and worldwide. Treatment leads to increased survival of patients, but they are at risk to experience psychological distress, including anxiety and depressive symptoms, and decreased health-related quality of life (HRQoL). This study investigated the relationship between psychological distress and HRQoL and related factors among women with breast cancer in Sweden. Methods This descriptive cross-sectional study was conducted in Sweden. A total of 481 women with breast cancer answered voluntarily a questionnaire about sociodemographic and support factors, psychological distress, and HRQoL. Data were subjected to Pearson’s correlation and linear regression analyses. Results Psychological distress was related to HRQoL in terms of body image, future perspective, side effects of systemic therapy, breast symptoms, arm symptoms, and hair loss. Women with lower age were associated with increased symptoms of anxiety, while those having undergone breast reconstruction were associated with increased symptoms of depression. Breast reconstruction and chemotherapy worsened body image, low support from partner decreased sexual functioning and enjoyment, and low support from physicians and nurses worsened future perspective, side effects of systemic therapy, breast symptoms, and indignation about hair loss. Conclusions Psychological distress was correlated with the HRQoL. Increased support from physicians, nurses, and husband/partner may increase the HRQoL among women with breast cancer. Breast cancer treatments such as breast reconstruction and chemotherapy were factors that decreased the psychological distress and increased the HRQoL.
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Ventegodt, Søren, Isack Kandel, Shimshon Neikrug, and Joav Merric. "Clinical Holistic Medicine: Holistic Treatment of Rape and Incest Trauma." Scientific World JOURNAL 5 (2005): 288–97. http://dx.doi.org/10.1100/tsw.2005.38.

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Studies indicate that at least 15% of the female population in western countries has experienced sexual abuse and severe sexual traumas. This paper explains how even serious sexual abuse and trauma can be healed when care and resources encourage the patient to return to the painful life events. When the physician cares and receives the trust of the patient, emotional holding and processing will follow quite naturally. Spontaneous regression seems to be an almost pain-free way of integrating the severe traumas from earlier experiences of rape and incest. This technique is a recommended alternative to classical timeline therapy using therapeutic commands. When traumatized patients distance themselves from their soul (feelings, sexuality, and existential depth), they often lose their energy and enjoyment of life. However, this does not mean that they are lost to life. Although it may seem paradoxical, a severe trauma may be a unique opportunity to regain enjoyment of life. The patient will often be richly rewarded for the extensive work of clearing and sorting out in order to experience a new depth in his or her existence and emotional life, with a new ability to understand life in general and other people in particular. So what may look like a tragedy can be transformed into a unique gift; if the patient gets sufficient support, there is the possibility of healing and learning. Consciousness-based medicine seems to provide severely traumatized patients with the quality of support and care needed for their soul to heal.
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Chun, Jennifer, Erica Brooke Friedman, Freya Ruth Schnabel, Martha Eddy, Shira Schwartz, Elizabeth Kern, Deirdre Kiely, Amber Guth, and Deborah M. Axelrod. "The breast cancer lifestyle intervention study." Journal of Clinical Oncology 31, no. 26_suppl (September 10, 2013): 112. http://dx.doi.org/10.1200/jco.2013.31.26_suppl.112.

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112 Background: Maintaining a healthy weight after breast cancer diagnosis has been associated with improved survival outcomes. Lifestyle interventions are particularly important in overweight women who are at an increased risk of overall and breast-cancer specific death compared to non-overweight women. The purpose of this study is to examine the barriers and acceptance of a lifestyle intervention program among overweight women with newly diagnosed breast cancer. Methods: The Breast Cancer Database of NYU Langone Medical Center was queried for women who were newly diagnosed with breast cancer and who had a body mass index (BMI) ≥25kg/m2. Eligible patients participated in the Moving for Life (MFL) exercise program for 16 sessions. Questionnaires were administered at baseline and at the end of the intervention. Descriptive statistics were used to summarize patient characteristics and paired t-tests were used to see if there were any significant differences before and after the intervention. Results: A total of 40 women were eligible to participate in the MFL exercise program. A total of 20 women declined to participate due to location, transportation limitations, and conflicts in schedule. Of the 18 women who enrolled in the MFL program, 13 (72%) were regular attendees and completed the study. The median age was 61 years (range: 38-76) and the average baseline BMI was 31kg/m2(range: 25-42). After completing the MFL intervention, there was a significant decrease in weight and BMI (p=0.04). The average weight loss was 10lbs. Participants also reported a greater enjoyment of exercise (p=0.02), as well as a decrease in pain related to treatment (p=0.05). Conclusions: Moving for Life is a unique exercise program for breast cancer patients and had a high rate of acceptance and completion in a cohort of overweight breast cancer patients. This study resulted in a statistically significant average weight loss of 10lbs, as well as a greater enjoyment of exercise and decrease in treatment-related pain which may impact long-term lifestyle changes. Longitudinal follow-up at 6- and 12-months will allow assessment of secondary endpoints, including exercise frequency and attitudes about exercise, allowing us to examine sustainability and changes in behaviors and attitudes over time.
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Froneman, Willemien. "Subjunctive pleasure: the odd hour in the boeremusiek museum." Popular Music 33, no. 1 (January 2014): 1–17. http://dx.doi.org/10.1017/s0261143013000500.

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AbstractThis paper introduces the subjunctive as a modality of engaging in musical life, in this instance the contemporary white folk music scene of boeremusiek in South Africa. The genre has repeatedly been portrayed as forever vanishing – a discourse that still characterises contemporary events put up by the largest boeremusiek organisation in South Africa, the Boeremusiekgilde (Boeremusiek Guild). The aim of the paper is to analyse the effects of discourses of nostalgia and salvage on participants' experiences of liveness in the present. It is shown how a deep dissatisfaction for live performance developed throughout the genre's 20th-century history. The repeated framing of present enjoyment in terms of past models of nationalist duty cast the actual actions of participants in the mode of subjunctive possibility, it is argued. As rituals of mourning, boeremusiek events bemoan personal histories fundamentally tainted by political transgression: the loss of intimate spaces of white innocence.
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Zanella-Calzada, Laura, Carlos Galván-Tejada, Nubia Chávez-Lamas, M. Gracia-Cortés, Rafael Magallanes-Quintanar, José Celaya-Padilla, Jorge Galván-Tejada, and Hamurabi Gamboa-Rosales. "Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients." Diagnostics 9, no. 1 (January 10, 2019): 8. http://dx.doi.org/10.3390/diagnostics9010008.

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Depression is a mental disorder characterized by recurrent sadness and loss of interest in the enjoyment of the positive aspects of life, in addition to fatigue, causing inability to perform daily activities, which leads to a loss of quality of life. To monitor depression (unipolar and bipolar patients), traditional methods rely on reports from patients; nevertheless, bias is commonly present in them. To overcome this problem, Ecological Momentary Assessment (EMA) reports have been widely used, which include data of the behavior, feelings and other types of activities recorded almost in real time through the use of portable devices and smartphones containing motion sensors. In this work a methodology was proposed to detect depressive subjects from control subjects based in the data of their motor activity, recorded by a wearable device, obtained from the “Depresjon” database. From the motor activity signals, the extraction of statistical features was carried out to subsequently feed a random forest classifier. Results show a sensitivity value of 0.867, referring that those subjects with presence of depression have a degree of 86.7% of being correctly classified, while the specificity shows a value of 0.919, referring that those subjects with absence of depression have a degree of 91.9% of being classified with a correct response, using the motor activity signal provided from the wearable device. Based on these results, it is concluded that the motor activity allows distinguishing between the two classes, providing a preliminary and automated tool to specialists for the diagnosis of depression.
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Gwark, Sung-chan, Sei Hyun Ahn, Woo Chul Noh, Eun Sook Lee, Yongsik Jung, Lee Su Kim, Wonshik Han, et al. "Similar negative emotional impact on hair loss in neoadjuvant endocrine therapy compared to neoadjuvant chemotherapy in young women with breast cancer from patient reported outcomes." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e19242-e19242. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e19242.

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e19242 Background: We aimed to evaluate patient-reported outcomes (PROs) in the NEST phase III trial, in which neoadjuvant endocrine therapy (NET) compared to conventional neoadjuvant chemotherapy (NCT) for hormone-responsive lymph node-positive premenopausal breast cancer. Methods: Premenopausal women with estrogen receptor (ER)-positive, HER2-negative, and lymph node-positive premenopausal breast cancer patients were enrolled. Patients were randomized to either 24 weeks of neoadjuvant chemotherapy with doxorubicin plus cyclophosphamide followed by taxane (T) or neoadjuvant endocrine therapy with goserelin and tamoxifen. PROs were assessed at day 1 (baseline) and at the end of treatment, using the breast cancer module of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 23 (EORTC QLQ BR23). ClinicalTrials.gov: NCT01622361. Results: 187 patients were randomly assigned to chemotherapy (n=95) or endocrine therapy (n=92), and 174 patients completed the 24 weeks of neoadjuvant treatment period (n=87, both). Baseline scores were similar between arms. No statistically significant between-treatment differences were observed for the function scales including body image, sexual functioning, and sexual enjoyment although endocrine treatment showed significant improvement in future perspective (HR=8.3, 95% CI:1.72-18.38; P=0.021). Even though no alopecia was reported in NET group, no statistically significant difference between both arms in the “upset by hair loss” was observed, in which NET group showed even worse score. Conclusions: Patients who received NET had significant improvement in a future perspective, however, a similar emotional negative impact on hair loss was observed compared with NCT despite no reported alopecia. Key words: breast cancer, patient-reported outcomes, quality of life, hair loss, EORTC QLQ-BR 23. Clinical trial information: NCT01622361 .
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Gwark, Sung-chan, Sei Hyun Ahn, Jin-Hee Ahn, Kyung Hae Jung, Sung-Bae Kim, Gyungyub Gong, Sae Byul Lee, et al. "Neoadjuvant endocrine therapy versus neoadjuvant chemotherapy in young women with breast cancer: Prognosis and axillary node surgery." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e12626-e12626. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e12626.

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e12626 Background: We aimed to evaluate patient-reported outcomes (PROs) in the NEST phase III trial, in which neoadjuvant endocrine therapy (NET) compared to conventional neoadjuvant chemotherapy (NCT) for hormone-responsive lymph node-positive premenopausal breast cancer. Methods: Premenopausal women with estrogen receptor (ER)-positive, HER2-negative, and lymph node-positive premenopausal breast cancer patients were enrolled. Patients were randomized to either 24 weeks of neoadjuvant chemotherapy with adriamycin plus cyclophosphamide (AC) followed by taxane (T) or neoadjuvant endocrine therapy with zoladex and tamoxifen. PROs were assessed at day 1 (baseline) and at the end of treatment, using the breast cancer module of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 23 (EORTC QLQ BR23). ClinicalTrials.gov: NCT01622361. Results: 187 patients were randomly assigned to chemotherapy (n = 95) or endocrine therapy (n = 92), and 174 patients completed the 24 weeks of neoadjuvant treatment period (n = 87, both). Baseline scores were similar between arms. No statistically significant between-treatment differences were observed for the function scales including body image, sexual functioning, and sexual enjoyment although endocrine treatment showed significant improvement in future perspective (HR = 8.3, 95% CI:1.72-18.38; P= 0.021). Even though no alopecia was reported in NET group, no statistically significant difference between both arms in the “upset by hair loss” was observed, in which NET group showed even worse score. Conclusions: Patients who received NET had significant improvement in a future perspective, however, a similar emotional negative impact on hair loss was observed compared with NCT despite no reported alopecia. Key words: breast cancer, patient-reported outcomes, quality of life, hair loss, EORTC QLQ-BR 23. Clinical trial information: NCT01622361.
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Zhang, Han. "Theoretical and Practical Basis of Marcuse's "False Need"." International Journal of Education and Humanities 4, no. 2 (September 14, 2022): 153–56. http://dx.doi.org/10.54097/ijeh.v4i2.1620.

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In the false enjoyment, people become insensitive, people's free choice becomes deceptive freedom. Human existence becomes a state of being uprooted and floating. In this state, the door to human potential is ruthlessly closed. False needs erode people's life, work, rest, leisure and other fields, and the flood of false needs has washed away people's bodies and minds. People in the false has lost the ability to distinguish between right and wrong, pathological as normal, normal as pathological. People lose what makes they human.
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Jones, Scott C. "The Values and Limits of Qohelet’s Sub-Celestial Economy." Vetus Testamentum 64, no. 1 (January 20, 2014): 21–33. http://dx.doi.org/10.1163/15685330-12301147.

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Abstract Qohelet draws upon the metaphors of a mercantile economy in order to assign values to human life. The primary context in which he calculates these values is time-under-the-sun. In the economy of time-under-the-sun, there are both absolute and relative credits. On the one hand, the inevitable onset of death reduces all credits or debits to zero. Yet on the other hand, Qohelet claims that the enjoyment of one’s profits during one’s lifetime is a relative credit. The sage, however, also perceives another sort of reckoning which reaches beyond his empirical observation. He speaks of a matrix outside of the rule of the sun, which he calls עולם. In this space beyond time God has ordained a judgment in which the pious will profit and the impious will suffer loss. The onset of a new order beyond the sun raises the possibility that zero might not be the final answer after all.
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Wedin, Sharlene, Karl Byrne, Katherine Morgan, Marie LePage, Rachel Goldman, Nina Crowley, Sarah Galloway, and Jeffrey J. Borckardt. "Presurgical Weight Is Associated with Pain, Functional Impairment, and Anxiety among Gastric Bypass Surgery Patients." Pain Research and Treatment 2012 (October 15, 2012): 1–5. http://dx.doi.org/10.1155/2012/412174.

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Chronic pain and obesity are significant public health concerns in the United States associated with significant levels of health-care expenses and lost productivity. Previous research suggests that obesity is a risk factor for chronic pain, mainly due to excessive weight placed on the joints. However, the obesity-pain relationship appears to be complex and reciprocal. Little work to date has focused on the relationship between weight and pain among patients undergoing gastric bypass surgery for weight loss. Patients scheduled to undergo bariatric surgery for weight loss at a large southeastern academic medical center () completed the Brief Pain Inventory (BPI), the Center for Epidemiological Studies 10-item Depression scale (CESD-10), and the Beck Anxiety Inventory (BAI). Higher presurgical weight was associated with higher pain-on-average ratings, higher functional impairment due to pain across the domains of physical activity, mood, walking ability, relationships, and enjoyment of life. Higher presurgical weight was associated with higher BAI scores, but weight was not related to depression. Findings suggest that bariatric surgery candidates report a moderate amount of pain prior to surgery and that presurgical weight is associated with higher pain, increased functional impairment due to pain, and increased anxiety. Anxiety was found to mediate the relationship between increased weight and pain.
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Mehling, Wolf E., Travis M. Scott, James Duffy, Rachel A. Whitmer, Margaret A. Chesney, W. John Boscardin, and Deborah E. Barnes. "Dyadic Group Exercises for Persons with Memory Deficits and Care Partners: Mixed-Method Findings from the Paired Preventing Loss of Independence through Exercise (PLIÉ) Randomized Trial." Journal of Alzheimer's Disease 78, no. 4 (December 8, 2020): 1689–706. http://dx.doi.org/10.3233/jad-200713.

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Background: Non-pharmacological therapies for persons with dementia (PWD) are needed. Objective: To develop and test the Paired Preventing Loss of Independence through Exercise (PLIÉ) program, an integrative group movement program for PWD and care partners (CPs). Methods: Participants were randomized to immediate or delayed start to Paired PLIÉ in community-based classes (1 hour, 2 days/week, 12 weeks, 3 home visits). Co-primary outcomes included standard measures of cognition, physical function,and quality of life (PWD) and caregiver burden (CPs) assessed by blinded assessors, analyzed using linear mixed models to calculate effect sizes for outcome changes during Paired PLIÉ, controlling for randomization group. Anonymous satisfaction surveys included satisfaction ratings and thematic analysis of open-ended responses. Results: Thirty dyads enrolled, 24 (80%) completed. PWD (mean age 80; 55% female) experienced significant improvement in self-rated quality of life (Effect Size+0.23; p = 0.016) when participating in Paired PLIÉ, while CPs experienced a non-significant increase in burden (–0.23, p = 0.079). Changes in physical and cognitive function in PWD were not significant. All CPs returning the satisfaction survey (n = 20) reported being moderately-to-highly satisfied with the program. Thematic analyses identified physical (e.g., sit-to-stand, more energy), emotional (enjoyment), and social benefits (peer-to-peer interaction) for PWD and CPs; challenges were primarily related to getting to the in-person classes. Conclusion: Paired PLIÉ is a promising integrative group movement program that warrants further study. It is feasible and may improve self-rated quality of life in PWD. Although CPs may experience increased burden due to logistical challenges, most reported high satisfaction and physical, emotional, and social benefits.
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Zhang, Yingcheng, and Gang Zhao. "LSEA: Software-Defined Networking-Based QoS-Aware Routing Mechanism for Live-Soccer Event Applications in Smart Cities." Wireless Communications and Mobile Computing 2020 (November 7, 2020): 1–8. http://dx.doi.org/10.1155/2020/8829868.

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The smart cities provide a better connection between services and citizens based on new Internet technologies. During the building process of smart cities, some burgeoning applications have been emerging and changing the daily lifestyle of people, e.g., live streaming applications. Especially, the live-soccer event applications have attracted much attention and can improve people’s enjoyment of life to a great extent, such as the Europe five major league matches and FIFA world cup. For such applications, the traditional routing strategies cannot do Quality-of-Service (QoS) awareness, and thus, the network performance and the Quality of Experience (QoE) of users cannot be guaranteed. In this paper, we employ Software-Defined Networking (SDN) to make QoS awareness for the special live-soccer event applications, in which the QoS-aware routing mechanism is proposed, called LSEA. Meanwhile, delay, delay jitter, and packet loss rate are considered as three objects. On this basis, the improved Dijkstra routing algorithm and SDN-based disjoint routing algorithm are devised. Finally, the proposed LSEA is implemented over Mininet, and the experimental results demonstrate its feasibility and efficiency.
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Ganz, Patricia A., Samia H. Lopa, Greg Yothers, Clifford Y. Ko, Amit Arora, James Norman Atkins, Nathan Bahary, et al. "Comparative effectiveness of sphincter-sparing surgery (SSS) versus abdomino-perineal resection (APR) in rectal cancer: Patient-reported outcomes (PROs) from NSABP R-04." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 3545. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.3545.

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3545 Background: R-04 is a trial of pre-surgical RT and either capecitabine or 5-FU with or without oxaliplatin in patients (Pts) with resectable rectal cancer. PROs were measured before treatment, post-RT, and 1 yr post-op. We compare PROs at 1 yr by type of surgery with hypothesis that APR Pts would have worse quality of life (QOL). Methods: Pts completed the FACT-C and EORTC-CR38 at all times. Baseline and 1 yr were compared within groups (SSS and APR) with paired t-test, and between groups at 1 yr, with adjustment for covariates of age, gender, clinical stage, baseline score, and surgery intent in a general linear model. These secondary/exploratory hypotheses were significant if p < 0.05. Results: 1,608Pts were randomized and 1405 completed baseline QOL form after consent, prior to treatment. 1,003 completed QOL form 1 yr post-op: 6 were ineligible, 10 did not have surgery, leaving 987 Pts. 615 had SSS and 372 had APR. 66.6% were male, 61.5% stage II, and almost all had post-surgical adjuvant chemotherapy. SSS Pts were significantly younger (60.3% vs. 53.5% < 59 yr, p=0.04). FACT-C total and subscale scores were not significantly different by surgery type at 1 yr, with only minimal decline from baseline in both groups. For SSS Pts, EORTC-CR38 scores significantly worsened for body image, sexual function, sexual enjoyment (all p <0.0001), while future perspective improved (p<0.0001) at 1 yr from baseline. All symptom subscales except weight loss and micturition showed worsened symptoms (GI tract, chemo side effects, defecation problems, sexual problems) all p < 0.0001 at 1 yr from baseline. Compared to APR Pts, SSS had less severe functional problems and symptoms, especially in sexual enjoyment, weight loss, GI symptoms, and body image, all significant. Conclusions: Contrary to prediction, there were no significant differences in FACT-C scores for SSS vs. APR. Symptoms and functional problems were detected by the EORTC-CR38, reflecting expected differences. The largest differences between the surgical treatments were for GI symptoms and body image. Information from these PROs may be useful in counseling Pts anticipating surgery for rectal cancer.
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Galván-Tejada, Carlos E., Laura A. Zanella-Calzada, Hamurabi Gamboa-Rosales, Jorge I. Galván-Tejada, Nubia M. Chávez-Lamas, Ma del Carmen Gracia-Cortés, Rafael Magallanes-Quintanar, and José M. Celaya-Padilla. "Depression Episodes Detection in Unipolar and Bipolar Patients: A Methodology with Feature Extraction and Feature Selection with Genetic Algorithms Using Activity Motion Signal as Information Source." Mobile Information Systems 2019 (April 23, 2019): 1–12. http://dx.doi.org/10.1155/2019/8269695.

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Depression is a mental disorder which typically includes recurrent sadness and loss of interest in the enjoyment of the positive aspects of life, and in severe cases fatigue, causing inability to perform daily activities, leading to a progressive loss of quality of life. Monitoring depression (unipolar and bipolar patients) stats relays on traditional method reports from patients; however, bias is commonly present, given the patients’ interpretation of the experiences. Nevertheless, to overcome this problem, Ecological Momentary Assessment (EMA) reports have been proposed and widely used. These reports includes data of the behaviour, feelings, and other type of activities recorded almost in real time using different types of portable devices, which nowadays include smartphones and other wearables such as smartwatches. In this study is proposed a methodology to detect depressive patients with the motion data generated by patient activity, recorded with a smartband, obtained from the “Depresjon” database. Using this signal as information source, a feature extraction approach of statistical features, in time and spectral evolution of the signal, is done. Subsequently, a clever feature selection with a genetic algorithm approach is done to reduce the amount of information required to give a fast noninvasive diagnostic. Results show that the feature extraction approach can achieve a value of 0.734 of area under the curve (AUC), and after applying feature selection approach, a model comprised by two features from the motion signal can achieve a 0.647 AUC. These results allow us to conclude that using the activity signal from a smartband, it is possible to distinguish between depressive states, providing a preliminary and automated tool to specialists for the diagnosis of depression almost in real time.
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Matuschek, Christiane, Carolin Nestle-Kraemling, Sylvia Wollandt, Vanessa Speer, Edwin Boelke, Stephan L. Roth, Werner Audretsch, et al. "Quality of life after preoperative radio-/chemotherapy in locally advanced breast cancer patients." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e12083-e12083. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e12083.

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e12083 Background: Preoperative radiotherapy and chemoradiotherapy (PRT/PCRT) represents an increasingly used clinical strategy in different tumor sites. However, concerns regarding a possible unfavorable influence on the clinical outcome still exist. The aim of the current study was to examine the long-term global health status in our series of LABC patients treated with PRT/PCRT followed by breast-conserving surgery (BCS) or mastectomy (ME). Methods: Of the 315 patients treated with PRT/PCRT in the years 1991 and 1999, 203 patients were still alive at long-term follow up of mean 17.7 years (range 14-21). Thirty-seven patients were lost to follow up and 58 patients refused to be contacted, which resulted in 107 patients (64 patients after BCS and 43 after mastectomy) being available and willing to undergo further clinical assessment. PRT/PCRT consisted of external beam radiation therapy (EBRT) with 50 Gy (5 × 2 Gy/week) to the breast and the supra-/ infraclavicular lymph nodes combined with a consecutive electron boost or (in case of BCS) a 10-Gy interstitial brachytherapy boost with Ir-192 prior to EBRT. Overall, chemotherapy was administered either prior to RT or concomitantly in the majority of patients. Quality of life (QoL) was assessed by EORTC QLQ-C30 questionnaires for overall QoL and EORTC QLQ-BR23 for breast-specific QoL. Results are reported using functional scales (body image, sexual functioning, sexual enjoyment, and future perspective) and symptom-related items (systemic therapy side effects, breast symptoms, arm symptoms, and upset by hair loss). The results were compared to a published reference cohort of n=2028 healthy adults (16-92 years), including n=1139 women (age 16-92 years). EORTC QLQ-C30 functional scales were also analyzed between different subgroups including an age-matched analysis with a two sided paired t-test. Results: In comparison with this healthy control group of 1139 women, we did not detect any significant differences for the functional scales measured by physical function, emotional well-being, cognitive, and social function as well as the symptom scales: fatigue, nausea, vomiting, pain, diarrhea and financial difficulties for both groups. However, significant inferior scores were found in the present study group regarding obstipation (p=0.013), loss of appetite (0.038), sleeping disorder (p=0.01) and dyspnoe (p=0.01). Conclusions: Taken together, retrospective as well as prospective data underline the feasibility of preoperative radiotherapy in breast cancer.
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Davies, Elizabeth A. "Why we need more poetry in palliative care." BMJ Supportive & Palliative Care 8, no. 3 (March 23, 2018): 266–70. http://dx.doi.org/10.1136/bmjspcare-2017-001477.

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ObjectivesAlthough many well-known poems consider illness, loss and bereavement, medicine tends to view poetry more as an extracurricular than as a mainstream pursuit. Within palliative care, however, there has been a long-standing interest in how poetry may help patients and health professionals find meaning, solace and enjoyment. The objective of this paper is to identify the different ways in which poetry has been used in palliative care and reflect on their further potential for education, practice and research.MethodsA narrative review approach was used, drawing on searches of the academic literature through Medline and on professional, policy and poetry websites to identify themes for using poetry in palliative care.ResultsI identified four themes for using poetry in palliative care. These concerned (1) leadership, (2) developing organisational culture, (3) the training of health professionals and (4) the support of people with serious illness or nearing the end of life. The academic literature was mostly made up of practitioner perspectives, case examples or conceptual pieces on poetry therapy. Patients’ accounts were rare but suggested poetry can help some people express powerful thoughts and emotions, create something new and feel part of a community.ConclusionPoetry is one way in which many people, including patients and palliative care professionals, may seek meaning from and make sense of serious illnesses and losses towards the end of life. It may have untapped potential for developing person-centred organisations, training health professionals, supporting patients and for promoting public engagement in palliative care.
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Amir, Nurmiati, Ronald Antoni, Asmarahadi Asmarahadi, Prianto Djatmiko, Siti Khalimah, Safyuni Naswati, Gerald M. Semen, Presetyawan Prasetyawan, and Widayanti D. Wulandari. "Rates and Risk Factors for Suicide Ideas among Schizophrenia Patients in Indonesia." Open Access Macedonian Journal of Medical Sciences 7, no. 16 (August 20, 2019): 2579–82. http://dx.doi.org/10.3889/oamjms.2019.393.

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BACKGROUND: Schizophrenia is associated with a high rate of suicide. AIM: Our study was aimed to identify the rates of suicide ideas in patients with schizophrenia as well as the risk factors associated with suicide ideas. METHODS: As many as 1130 subjects were evaluated using the Indonesian version of Diagnosis Interview for Psychosis (DIP) to establish the diagnosis of schizophrenia. Subjects aged 18-65 years. The risk factors were socio-demographic data, mental disorder history in the family, clinical symptoms and clinical course of schizophrenia. Risk factors that have the strongest correlation with suicide ideas were analysed using multivariate logistic regression analysis. RESULTS: About 6.1% of subjects reported suicide ideas in their life. The age of disease onset (p = 0.006), family history of schizophrenia (p = 0.013), poor concentration (p = 0.032), loss of enjoyment (p = 0.000), guilty feeling (p = 0.000), family history of mental illness (p = 0.000), nihilistic delusion (p = 0.001) and alcohol abuse (p = 0.000) were significantly associated with suicide ideas. CONCLUSION: Suicide idea is quite common in people with schizophrenia. Evaluation and management of risk factors associated with suicide ideas should be performed to prevent suicide attempts or death. Suicide ideas and risk factors can become clinical parameters in the instrument of suicide prevention.
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Cabanillas-Cruz, Esther, Christian López-Rodriguez, Cristina Romero-Blanco, and Susana Aznar. "A Qualitative Analysis of an Aerobic Interval Training Programme for Obese Outpatients Carried Out in a Hospital Context." International Journal of Environmental Research and Public Health 17, no. 1 (January 2, 2020): 312. http://dx.doi.org/10.3390/ijerph17010312.

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Purpose: To describe the experience of obese adults following participation in an indoor aerobic interval training (AIT) intervention. Methodology: Qualitative, in-depth semi-structured individual interviews, using phenomenology, with 24 obese adults (body mass index (BMI) ≥30 kg/m2) from the Endocrinology Department, at the Severo Ochoa Hospital in Leganés (Madrid). Questions were related to: (a) The physical activity (PA) programme, (b) their perspectives of the activity and exercise environment and (c) the perceived benefits from participation. Data were analysed with a constant comparison approach. Results: The main patients’ reasons for beginning the programme were motivations to take part including weight loss, health improvement and doctors’ recommendation. Also, patients showed doubts and feelings of apprehension at the beginning of the intervention. Patients highlighted the role of the instructor, feelings of exercising in a safe environment, a good intervention and accessibility of the facility. They reported an improvement in their quality of life and recommended continuing the program. Conclusions: (1) Common themes in the qualitative analysis included enjoyment of the activity and a desire to maintain physical fitness, (2) AIT was perceived as a suitable exercise programme for this population and (3) recommendations for further investigation to understand the role of PA programmes for people with obesity.
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Rao, Sujay. "Arbiters of Change: Provincial Elites and the Origins of Federalism in Argentina's Littoral, 1814–1820." Americas 64, no. 4 (April 2008): 511–46. http://dx.doi.org/10.1353/tam.2008.0068.

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Early in 1817, in the tiny port of Rosario, a deeply troubled Comandante Tomás Bernal sat down at his desk to pen a confidential private letter to Supreme Director Juan Martín de Pueyrredón, head of the national government based in Buenos Aires. Nearly seven years after the May Revolution against Spain, the territory that would later become Argentina found itself buffeted by civil war. Bernal's region, the jurisdiction of the city of Santa Fe, just up the Paraná River from Buenos Aires, found itself enmeshed in the bitter conflict between the government in Buenos Aires, the former viceregal capital, and its principal rival, José Gervasio Artigas, leader of a federalist alliance based in the nearby Banda Oriental, modern Uruguay. Desperate to contain disputes between the national government and the recently created government of Santa Fe, Bernal counseled restraint. However, he knew that Buenos Aires and Santa Fe were on the brink of war. “For my part,” he wrote Pueyrredón:you can count it as certain that in such a war I will not take part but I will not be able to keep myself from lamenting the loss of a precious part of this land, which has sworn to sacrifice its life only against a foreign enemy that would oppose the enjoyment of its rights.
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Antonya, Csaba, and Silviu Butnariu. "Preservation of Cultural Heritage Using Virtual Reality Technologies and Haptic Feedback: A Prototype and Case Study on Antique Carpentry Tools." Applied Sciences 12, no. 16 (August 10, 2022): 8002. http://dx.doi.org/10.3390/app12168002.

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Over the last decade, there have been intense concerns at the European and global level regarding the recovery, protection, and promotion of cultural heritage in various forms: monuments, historical sites, artifacts, cultural expressions. The world is becoming more and more aware of the loss of honor elements of cultural heritage due to the passage of time, natural or man-made disasters, negligence, and improper conservation. This paper aims to develop a tool to improve the visibility of elements that may become rare in everyday life over the coming years, becoming elements of cultural heritage. The paper refers to a haptic system for simulating kinematic and dynamic operating conditions based on an articulated mechanism, more precisely, the simulation of the operation of a manual saw as a carpentry tool, visualizing the sawing maneuver and increasing the level of understanding of the operation by the possibility of modifying the working parameters. In the developed virtual reality environment, the user’s perception can benefit by evoking two of their senses—the user can see the operation of the hand saw and can feel the manual process of cutting wood. User studies were carried out to evaluate the usability and performance of the virtual reality application. In two test scenarios, 20 people gave positive feedback in using custom-made haptic devices for various categories (engagement, manipulability, enjoyment, realism, usability, overall experience).
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Madhakomala, R., and Johansyah Anwar. "LEARNING LIFE BALANCE: A STUDY TO REGAIN MENTAL PEACE AND MENTAL HEALTH OF SENIOR HIGH STUDENTS." IJER - INDONESIAN JOURNAL OF EDUCATIONAL REVIEW 4, no. 1 (July 3, 2017): 31. http://dx.doi.org/10.21009/ijer.04.01.04.

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The aim of this study is to observe the level of happiness enmjoyed among senio high students related to current school practices and national learning system regulated by the authorities.The world of learning has changed when school grading has been becoming as one of the most obligating and influencing source of educational success in within the institution. The historical myth of study with fun and enjoyment has gradually but sure moved to the sense of study hard for the sake of the future by consuming most of the daytime hours.Nevertheless, this is when the problem of lack of students’ quality time commences. Students do not realize that they are moving to the unsatisfied part of the learning life, as so many times they are also intrigued with and by computers; when unconsiously they lose the lovely ones and the world outside.This study attempts to show how senior high students can achieve the so-called learning life balance to regain their mental peace by more contacts and relationships with families, the environment, and the world around. This is how the world of educating has to recognize and understand the value of happiness of a senior high student. This is how the regulator has to manage the system to flow to the building and the establishment of the well-being of nowadays students.
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Quadrini, Isabella, Deema Ujayli, and Amanda Lynch. "“The Best Portion of Your Life Is Small:” The Impact of Bariatric Surgery on Food Choices and Eating Motivations." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 556. http://dx.doi.org/10.1093/cdn/nzaa046_056.

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Abstract Objectives The purpose of this study was to describe food choice changes and explain food choice rationales to understand dietary intake patterns in the first year following bariatric surgery. Methods Thirty bariatric surgery candidates (19 sleeve gastrectomy, 11 gastric bypass) were recruited to participate in a mixed methods study. Semi-structured interviews were conducted with participants pre-surgery and at 6- and 12-months post-surgery to explore food choices, dietary patterns and behaviors. Block Food Frequency Questionnaires (FFQ) were completed at each time point. Transcripts were coded using a constant comparative method. Emergent themes were compared across time points. A matrix was created to display food classifications and dietary patterns. Pre-and post- surgery food group and macronutrient comparisons were made using paired t-tests. Results Three themes emerged to describe food choice patterns: macronutrient content at meals and snacks, eating structure and routine, and “eating out” habits. Both pre- and post-surgery, protein foods (e.g., dairy and lean meats) and vegetables were the most commonly reported “healthy” foods and were valued for satiety. Unhealthy foods included desserts, sweets, salty snacks, and fruit. Participants unanimously described reduced portion size, but not all chose foods based on perceptions of health. Other important food choice motivators included hunger, convenience, control and enjoyment. FFQ data revealed that participants reduced intake of all food groups at 6 months with increases in servings of fat (P &lt; 0.05) 12 months. At 6 months, there was an increase in % calories from protein (P &lt; 0.000) and a decrease in % calories from sweets (P &lt; 0.021). At 12-months, there was a reversal of this trend: Protein decreased to 20% of calories (P &lt; 0.007) and sweets increased to 18% (P &lt; 0.045). Conclusions Participants’ perceptions of healthy and unhealthy food did not drive a majority of food choice decisions following bariatric surgery. Post-surgery changes in food choice patterns and dietary behaviors may not be long-term, which could impact weight loss outcomes. Funding Sources Oakland University and William Beaumont Hospital.
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Plotti, Francesco, Corrado Terranova, Stella Capriglione, Stefania Crispino, Alessandra Li Pomi, Carlo de Cicco Nardone, Roberto Montera, Pierluigi Benedetti Panici, Roberto Angioli, and Giuseppe Scaletta. "Assessment of Quality of Life and Urinary and Sexual Function After Radical Hysterectomy in Long-Term Cervical Cancer Survivors." International Journal of Gynecologic Cancer 28, no. 4 (May 2018): 818–23. http://dx.doi.org/10.1097/igc.0000000000001239.

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AimsThe aim of this study was to evaluate long-term quality of life and urinary and sexual function in long-term cervical cancer survivors previously treated with radical hysterectomy (RH) type C2/type III.MethodsAll patients who presented at Campus Bio-Medico of Rome for RH type C2/type III for cervical cancer were considered eligible for this retrospective study protocol. We included exclusively patients with complete response to primary treatment with at least 36 months of follow up. Included subjects were interviewed with the European Organization for Research and Treatment of Cancer QLQ-CX24 Questionnaire, European Organization for Research and Treatment of Cancer QLQ-C30, and an Incontinence Impact Questionnaire 7.ResultsFrom January 2004 to June 2014, 251 patients affected by locally advanced cervical cancer were treated at Campus Bio-Medico of Rome treated with type C2/type III RH. At time point of March 2017, 90 patients were included with a mean age of 55.6 ± 8.5 years. The questionnaires were administered after a median follow-up of 49 months after the end of therapy. The symptoms of fatigue, nausea and vomiting, appetite loss, pain, insomnia, and dyspnea, as well as a negative financial impact, were reported as not frequent and rarely disabling. On the contrary, patients frequently reported gastrointestinal complaints. Diarrhea was present in 6% of patients and was referred as mild; constipation was present in 75% of women and was reported as mild in 30% of cases, moderate in 30%, and severe in 15%. Concerning sexual activity, data indicated a good level of sexual enjoyment with a slight worsening of sexual activity. Incontinence was reported in 28% of cases and appeared to be mild and rarely disabling (all mean values <2).ConclusionsWaiting for ongoing randomized controlled trials, this study confirmed that RH may be considered as a useful treatment plan, according to its negligible long-term impact on quality of life, urinary dysfunction, and sexual function.
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Brandberg, Yvonne, Theodoros Foukakis, Anne Andersson, Judith Bjohle, Ana Bosch, Lena Carlsson, Zakaria Einbeigi, et al. "One-year follow-up of health-related quality of life in the Swedish PREDIX HER 2 trial, evaluating docetaxel, trastuzumab sc, pertuzumab versus trastuzumab emtansine as neoadjuvant treatment of HER2 positive breast cancer." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): 590. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.590.

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590 Background: Neoadjuvant therapy combining docetaxel, trastuzumab and pertuzumab (DTP) was compared to trastuzumab emtansine (T-DM1) in the randomised phase II PREDIX HER2 trial. Patients, ≥18 years with HER2 positive breast cancer, ≥20mm or with verified lymph node metastases, were randomised to six courses of DTP (Standard group) or T-DM1 (Experimental group) before surgery. After operation patients in the Standard arm received two, and those in the Experimental arm four courses of EC. Since there were no differences in proportions of complete response at surgery and in the event-free survival between the groups, health-related quality of life (HRQoL) is of special interest. Methods: HRQoL was measured, using European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 + EORTC QLQ-BR23, before randomisation, after six courses before surgery, at three months and one year after surgery. Results: Response rate for the questionnaires varied between 87% and 99% for the 198 included patients. There were no between-group differences at baseline. Results after six courses revealed statistically significant differences (p≤0.01), favouring the Experimental group on 12 out of 21 of the EORTC QLQ-C30 and BR23 variables (Physical-, Role-, and Social- functioning, Global quality of Life, Fatigue, Dyspnea, and Diarrhea, Body image, Sexual functioning, Sexual enjoyment, Systemic therapy side effects and Upset by hair loss). Three months after surgery, however, statistically significant differences in favour of the Standard group were found for six variables (Physical functioning, Nausea/vomiting, Dyspnea, Constipation, Systemic therapy side effects, Upset by hair loss). No other between group differences were found with one exception: lower levels of Breast symptoms in the Experimental group. One possible explanation is that patients in the Experimental group were still on chemotherapy at that assessment point, whereas the majority in the Standard group had terminated their treatment. No differences were found between the groups at the one-year after surgery follow-up, where the levels on most variables had returned to baseline values. Conclusions: HRQoL was better in the Experimental group during neoadjuvant treatment. Three months after surgery, however, HRQoL was in favour or the Standard arm. HRQoL returned to baseline levels for most variables at the one-year follow-up and no between-group differences were found. Clinical trial information: NCT02568839 .
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Brandberg, Yvonne, Anne Andersson, Judith Bjohle, Ana Bosch, Lena Carlsson, Ann Charlotte Dreifaldt, Zakaria Einbeigi, et al. "Health-related quality of life in the Swedish PREDIX HER2 trial, evaluating docetaxel, trastuzumab, pertuzumab versus trastuzumab emtansine as neoadjuvant treatment of HER2-positive breast cancer." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 583. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.583.

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583 Background: Neoadjuvant therapy combining docetaxel, trastuzumab and pertuzumab (DTP) was compared to trastuzumab emtansine (T-DM1) in the randomized phase 2 PREDIX HER2 trial. Patients, ≥18 years with HER2 positive breast cancer, ≥20mm or with verified lymph node metastases, were randomized to six courses of DTP (Standard arm) or T-DM1 (Experimental arm). Primary endpoint was pathological objective response to primary medical therapy at post-treatment surgery. Health related quality of life (HRQoL) was a secondary outcome, and is of specific interest as there was no difference between the randomization groups regarding the main endpoint (results presented in a separate abstract sent to ASCO 2019, Bergh et al.). Methods: Of 202 randomized patients, 190 are available for evaluation at this point. HRQoL was measured, using EORTC QLQ-C30 + EORTC QLQ-BR23, at baseline before randomization and after six courses. Results: No differences between the randomization arms were found at baseline. Results after six courses, based on 163 patients (86%) and adjusted to baseline values, revealed statistical significant differences (p≤0.01), favoring the experimental T-DM1 arm on 7 out of 15 of the EORTC QLQ-C30 variables (Physical functioning, Role functioning, Social functioning, Global quality of Life, Fatigue, Dyspnea, and Diarrhea). For the breast cancer specific questionnaire (EORTC-BR23), the experimental arm scored statistically significantly better on 5 out of 7 subscales (Body image, Sexual functioning, Sexual enjoyment, Systemic therapy side effects and Upset by hair loss). All of the statistical significant differences were of moderate or large clinical significance (≥10 scale scores). No differences between the randomization arms were found for the remaining HRQoL variables. Conclusions: The experimental arm reported better HRQoL than the control arm after six courses. Trastuzumab emtansine may be a useful treatment alternative due to better HRQoL and lower toxicity. Clinical trial information: NCT02568839.
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İbrahimoğlu, Özlem, Sevinc Mersin, and Eda Akyol. "The Experiences of Patients with Deep Brain Stimulation in Parkinson’s Disease: Challenges, Expectations, and Accomplishments." Acta Medica Academica 49, no. 1 (August 1, 2020): 36. http://dx.doi.org/10.5644/ama2006-124.281.

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<p><strong>Objectives. </strong>Deep brain stimulation (DBS) is a safe and effective alternative treatment of some movement disorders such as Parkinson's disease. Although DBS is an effective treatment for Parkinson's disease, because of the necessity of surgical intervention, follow-up and the effects on symptoms, this study was carried out to determine the challenges, expectations and accomplishments of patients with DBS in Parkinson’s disease.</p><p><strong>Materials and Methods. </strong>This qualitative study was carried out at the Neurosurgery Department of a research hospital in Turkey with seven patients who underwent DBS between 2008 and 2018. In the study, the challenges, expectations, and accomplishments of patients were investigated by using three focus group interviews in October 2018.</p><p><strong>Results. </strong>Among the participants, six patients were male, and one patient was female. The mean age of the patients was 56.85}16.48. Three main themes were revealed in the study. These were (1) Reborn; decrease in dependence, sense of accomplishment, enjoyment of life, (2) Prejudice; perceived as severely ill by others and (3) Fear; not being accustomed to the device, loss of device function.</p><p><strong>Conclusion. </strong>The results obtained from this study can be used in the process of adaptation to this process by discussing and evaluating the challenges, expectations and accomplishments of the Parkinson's patient in DBS with healthcare professionals and other patients.</p>
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Sawada, Namie Okino, and Alexandra Paola Zandonai. "Characteristics of chemotherapy-induced peripheral neuropathy in patients with breast cancer." Journal of Clinical Oncology 33, no. 28_suppl (October 1, 2015): 85. http://dx.doi.org/10.1200/jco.2015.33.28_suppl.85.

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85 Background: In Brazil, breast cancer has the second highest incidence of neoplasms, the most common among women. It is expected there will be 57,120 new cases and a risk 56.09 cases per 100 thousand women. For its treatment, neurotoxic chemotherapeutics that can cause chemotherapy-induced peripheral neuropathy (CIPN) are used. Methods: This is an exploratory descriptive study developed in a cancer treatment reference hospital in the city of Sao Paulo, Brazil. Aim: To search the patients with breast cancer during treatment with neurotoxic agents and evaluate the presence of CIPN with application of Chemotherapy-Induced Peripheral Neuropathy Assessment Tool questionnaire (CIPNAT). Results: The sample was 44 women with a mean age of 52 years (SD = 10.54), 47.7% had local disease, 72.7% were treating with taxanes neurotoxic agents. The main neuropathic symptoms measured at CIPNAT: 75% had motor symptom weakness with an average score for severity of 6.45 causing an average of distress 5.36; 65.9% muscle and joint pain average severity of 6.31 causing an average of 5.59 distress; and 56.8% sensitive symptom numbness in the hands average severity of 4.76 causing an average of 3.52 distress. These symptoms had a negative impact in the activities of daily living (ADL) such as physical exercise (mean score = 5.32), enjoyment of life (mean score = 4.77) and leisure activities (mean score = 4, 03). Although few (13.6%) reported that suffered some injury or accident due to CIPN. Discussion: The results are consistent with those presented in the scientific literature, but measured with other assessment tools such as the NCI CTCAE, WHO and EORTC QLQ-C30 and CIPN20, which also showed that motor disorders (weakness, muscle cramps and loss of strength in the hands) and sensory (numbness and tingling in the hands and feet). Conclusions: The study explores the relationship between CIPN and ADL affected during treatment for breast cancer. Through the motor and sensory symptoms reported by CIPNAT, nursing will have grant to develop educational strategies to prevent and minimize negative impacts on the quality of life of women with breast cancer undergoing treatment with neurotoxic agents.
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Spencer, J. R. "Public Nuisance—A Critical Examination." Cambridge Law Journal 48, no. 1 (March 1989): 55–84. http://dx.doi.org/10.1017/s0008197300108347.

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Why is making obscene telephone calls like laying manure in the street? Answer: in the same way as importing Irish cattle is like building a thatched house in the borough of Blandford Forum; and as digging up the wall of a church is like helping a homicidal maniac to escape from Broadmoor; and as operating a joint-stock company without a royal charter is like being a common cold; and as keeping a tiger in a pen adjoining the highway is like depositing a mutilated corpse on a doorstep; and as selling unsound meat is like embezzling public funds; and as garaging a lorry in the street is like an inn-keeper refusing to feed a traveller; and as keeping treasure-trove is like subdividing houses which so “become hurtful to the place by overpestering it with poor.” All are, or at some time have been said to be, a common (alias public) nuisance. The definition of this offence, according to Archbold's Criminal Pleading and Practice, is as follows: “Every person is guilty of an offence at common law, known as public nuisance, who does an act not warranted by law, or omits to discharge a legal duty, if the effect of the act or omission is to endanger the life, health, property, morals, or comfort of the public, or to obstruct the public in the exercise or enjoyment of rights common to all Her Majesty's subjects.” The person who commits a public nuisance incurs liability to life imprisonment and unlimited fines. He can be made vicariously liable for the offence if it is committed by his servants. He can be ordered to stop it by an injunction, and made to pay damages in tort if it causes anyone loss. With such a broad concept in existence, backed with such broad remedies, what need have we of any other criminal offence?—or torts?—or remedies in administrative law?
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Lee, Hae Sung, and Jong-Hee Kim. "Obese Frailty and Combined Exercise." Exercise Science 30, no. 4 (November 30, 2021): 419–31. http://dx.doi.org/10.15857/ksep.2021.00430.

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PURPOSE: Frailty is a geriatric syndrome that impairs the health and quality of life of older adults. While unintended weight loss is known to be a primary risk factor for frailty, obesity has also been closely associated with frailty. Combined exercise is thought to be an effective way of resolving obesity and frailty, but studies demonstrating the effect of combined exercise on obese frailty are lacking. In this review, we seek to understand the relevant mechanisms by exploring prior studies on obese frailty, and provide the implications of appropriate combined exercise interventions for obese frailty.METHODS: To collect data for this study, we used academic search systems such as Scopus, Google Scholar, PubMed, and Web of Science. The keywords used for the search were a combination of words such as ’obesity’, ‘frailty’, ‘combined or multicomponent exercise’, and ‘older or elderly adults’.RESULTS: The results from the 16 selected articles confirmed that combined exercise reduces body weight, percentage of body fat, and risk of falls. Moreover, it improves muscle strength, balance, and walking function of the obese frail population.CONCLUSIONS: As we have confirmed the positive outcomes on the combined exercise for obese frail older adults, an optimal exercise program needs to be presented. Older adults with obesity are recommended to exercise at least 2-3 times a week during the initial period. Further, they should begin with low-intensity walking, full-body exercise, balance, and flexibility exercises, then gradually increase the exercise volume. Moreover, to facilitate the positive outcomes of physical training and to encourage autonomy and enjoyment of exercise among obese frail older adults, a novel method and an individualized scientific exercise program need to be developed.
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Ravnborg, H. M., and K. M. Jensen. "The water governance challenge: the discrepancy between what is and what should be." Water Supply 12, no. 6 (October 1, 2012): 799–809. http://dx.doi.org/10.2166/ws.2012.056.

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In 2010, the UN General Assembly declared the right to safe and clean drinking water and sanitation as a human right that is essential for the full enjoyment of life and all human rights. Yet, findings from the Competing for Water research programme suggest that all too often, people in need of water for domestic purposes lose out to people and companies who claim access to water for productive purposes. Likewise, in many countries, specific water authorities at national as well as basin and watershed level have been formed and assigned the responsibility to allocate water according to the water policy and the associated legal framework. Yet, findings from the Competing for Water research programme show that real-world water allocation takes place through a wide array of institutions, ranging from the rural community, over agreements mediated by local lawyers, district officials and non-governmental organisations, to decisions made in the president's office. The Competing for Water programme entails empirical research conducted in Bolivia, Mali, Nicaragua, Vietnam and Zambia. Based on findings from this research, this paper identifies the discrepancies between statutory and actual water governance, analyses the underlying causes and explores the implications for ongoing water governance reform.
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Mathis, Shannon L. "Factors associated with mobility apprehension in persons with lower limb amputation." Prosthetics and Orthotics International 44, no. 4 (April 27, 2020): 208–14. http://dx.doi.org/10.1177/0309364620915017.

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Background: Factors that are related to mobility apprehension were measured in a sample of persons with lower-limb amputation. Objectives: The purpose was to determine whether intensity, interference, or catastrophizing are associated with mobility apprehension. Study design: Cross-sectional study. Methods: Persons with amputation of a lower limb who were attending a national limb loss conference were recruited to complete a survey. Subjects were administered the Tampa Scale for Kinesiophobia to measure mobility apprehension. The Brief Pain Inventory was administered to quantify the affect of pain on general activity, walking ability, and enjoyment of life. The Pain Catastrophizing Scale was administered to assess the tendency to ruminate and magnify pain sensations. A multivariable linear regression was performed to determine factors associated with mobility apprehension. Results: Fifty-three people with lower-limb amputation participated in the study. The mean (standard deviation) score for mobility apprehension was 34.2 (6.0). Mean (standard deviation) pain intensity and interference scores were 1.6 (1.7) and 2.5 (2.6), respectively. The mean (standard deviation) pain catastrophizing score was 9.1 (10). Pain catastrophizing was the only variable associated with higher mobility apprehension ( β = 0.31, p < 0.001, R2 = 0.32). Results suggest that for every one-point increase in the pain catastrophizing score, mobility apprehension will increase by 0.3 of a point. Conclusion: These preliminary results suggest that pain catastrophizing was related to mobility apprehension in this cohort of persons with lower-limb amputation. This relationship indicates that the exploration of avoidance behaviors, such as pain catastrophizing, may be useful when developing a program for physical rehabilitation. Clinical relevance Pain catastrophizing, an avoidance behavior, may be associated with higher levels of mobility apprehension in persons with major lower-limb amputation. Understanding the impact of fear-avoidance behavior will allow clinicians to identify individuals at risk for poor outcomes following amputation surgery and to develop psychological strategies to complement treatment.
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Wezzie, Masadza, Siankulu Elaine, Kawalika Micheal, Victoria Mwiinga-Kalusopa, and Patricia Katowa-Mukwato. "Quality of life of Zambian breast cancer women receiving care at the cancer diseases hospital Lusaka." Journal of Nursing Education and Practice 10, no. 9 (June 8, 2020): 57. http://dx.doi.org/10.5430/jnep.v10n9p57.

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Background: Breast cancer is the most frequently diagnosed malignancy among women in the world with an estimation of 1.67 million new diagnoses worldwide in 2012 estimated at 25% of all cancers. In Zambia, breast cancer is the second most common cancer affecting women and accounts for 9% of all histologically proven cancers among patients admitted at the country’s only Cancer Diseases Hospital Most of the patients receive multiple treatment modalities; Surgery, Chemotherapy, Radiation Therapy and Hormonal Therapy, each with its own long-term side effects with a potential to affect the women’s functionality, self-image and sexuality consequently the general quality of life of these women.Methods: A descriptive cross-sectional study design was used to investigate the Quality of Life (QoL) and factors influencing QoL among women with breast cancer receiving care at Zambia’s only Cancer Diseases Hospital. A total of 130 breast cancer patients on treatment who were willing to participate in the study were selected using simple random sampling. Data was collected using the European Organization for Research and Treatment in Cancer Quality of Life Questionnaire (EORTCQLQ–C30) and its breast cancer supplementary measure (QLQ-BR23). The tool assessed QoL across the physical, role, cognitive, emotional, and social functioning and sexual function domains.Results: Overall, just about half (52.5%) of the 130 respondents had high Quality of Life. QoL which was measured by the EORTCQLQ–C30 under the five domains (Physical, role, emotional, cognitive and sexual functioning) was high in four out of the five which scored above the global mean score of 68. Only the emotional functioning domain scored (65) below the mean. Conversely, the symptom scale scored high on all the eight sub items of fatigue, nausea and vomiting, pain, dyspnea, insomnia, appetite loss, constipation and diarrhea which signified high symptom experience among respondents. Similarly using the breast cancer supplementary measure (QLQ-BR23), two out of the four functional subscales (body image and sexual functioning) score high than average while sexual enjoyment and future perspectives score low. On the symptom scale, three out of the four scales scored higher than averages, signifying high symptom experience. Demographic characteristics which had significant association with QoL were age (p < .023), level of education (p < .023) and financial status (p < .000). Other factors that had significant association with QoL were type of treatment being received (p < .023), the severity of condition (p < .000), access to health care services (p < .000) and social support (p < .000).Conclusions: A diagnosis of breast cancer and its subsequent treatment affects several facets of a woman’s life ranging from physical, emotional, social and financial aspects consequently affecting the entire QoL. However the QoL varies and is influenced by a number of factors including age at diagnosis of cancer, level of education, financial status, type of treatment received, severity of the condition, access to health care facilities and social support. Therefore any intervention aimed at improving the QoL should be multidimensional.
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Musii, V. B. "SEMANTICS OF THE TITLE OF ROMAN MALINOVSKY’S STORY «TWO MINUTES BEFORE MIDNIGHT»." Opera in linguistica ukrainiana, no. 29 (November 9, 2022): 69–77. http://dx.doi.org/10.18524/2414-0627.2022.29.262386.

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The article is devoted to the study of such an element of paratext as a title. The object of the study is the story of the modern Ukrainian writer Roman Malinovsky “Two minutes before midnight”. It was published in the book “Sweet Life” in 2021, and it reflected the author’s consciousness of the danger to the life of mankind that the weapon carries. The purpose of the article is to reveal the meanings of the story’s title, to substantiate its representative, textforming role, to determine how the title helps to understand the author’s concept of reality, embodied in the work. To achieve the goal, the vocabulary (sun, wind, stars) included in the semantic field “space objects” was analyzed. The position is substantiated that the key role in the story is played by the image of the stars, this is the dominant component of the semantic field, closest to the core. The direct meaning of this word (what is seen in the night sky) and its metaphorical meanings are highlighted: a) space object; b) a cigarette light during a friendly meeting; c) the wreckages of burning satellites; d) flashes of nuclear missiles. The thesis is substantiated that the motif that appears at the beginning of the work is the expectation of an unusual cosmic phenomenon – fall of stares, with which the aesthetic (enjoyment of their beauty) is associated, as well as the hope that the wishes come true, is replaced at the end of the work by a statement of the launch of rockets that bring death people, including those who gathered to enjoy the view of the stars and hoped for a happy future. As a result, such semantic oppositions were indicated in the description of the picture of approaching to night (the key word in the title of the story) and in the semantic field “signs of the Space”: “day - night”, “present - future”, “life - death”, “beautiful – disgraceful, unhumane”, “space – chaos”. Attention is drawn to the fact that the vector in the description of what is happening is: from a variety of colors - to plunging the world into darkness, from light - to its dispersion. Hence the dominance of the semantics of extinction, approaching death. As a result, the interpretation of the night as a boundary between existence and its loss is proposed. The conclusion is made about the main meaning of the title of the whole work: two minutes before night - what happened two minutes before the death of mankind.
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Et.al, Chang-yong Joo. "Collaborative Maze Game Using EEG for Paralyzed Patients." Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, no. 6 (April 10, 2021): 849–55. http://dx.doi.org/10.17762/turcomat.v12i6.2108.

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The brain movement of a general paralysis patient is normal even if the nerve cells that connect the brain and muscles are damaged and the body movement is hindered. When these patients live alone and cannot perform daily activities, they lose the motivation to live, their brains become dull, and their self-esteem degrades. Therefore, a method should be developed such that these patients can perform brain exercises on their own. The development of a maze-finding game based on mutual cooperation using electroencephalography (EEG) for patients with general paralysis is described herein. Paralyzed Patient 1 can view an overview map and identify the path to a destination. When this is sent to Paralyzed Patient 2 through brain waves, direction indications appear on the screen viewed by Patient 2. Patient 2 verifies the signal conveyed by Patient 1 and controls the character in the perceived direction using brain wave signals. In this game, EGG data through the EPOC+ device of Emotiv Co. are collected, and the maze game implemented by the patient’s EEG signal can be played. Excitement and interest arise when two people collaborate compared with when they are playing games in solitude. This finding suggests that paralyzed patients can exercise their own brain without any assistance, enabling them to experience more enjoyment in life and improve their self-image compared with when they are collaborating and interacting with assistants.
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Barghout, V., L. Abetz, R. Arbuckle, V. Bosch, Y. Hei, and F. Saad. "Effect of zoledronic acid (Z) on pain in prostate cancer patients with bone metastases based on performance status." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 14544. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.14544.

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14544 Background: Z has demonstrated efficacy in reducing, preventing, delaying the occurrence of an SRE (Skeletal Related Event) including pathologic fractures, severe bone pain requiring radiation therapy, spinal cord compression, surgery to bone and hypercalcemia of malignancy which could lead to a loss of independence. Effects of Z on pain were analyzed in a subgroup of patients based on performance status. Methods: Subjects were randomised to Z 4mg (n = 201) or placebo (n = 201). The short form of the Brief Pain Inventory (BPI) was administered at baseline (visit 2), and visits 3 (weeks 3–4), 4 (weeks 6–8), and then every second visit (every 6 weeks) until study end. Changes in BPI individual item scores and the Pain severity and Pain Interference scale scores were compared between Z and placebo groups. Post baseline missing data were replaced by Last Observation carried forward (LOCF). Changes in scores were examined in the subgroup of patients with ECOG performance status scores of ≥ 1. Results: For patients ECOG score of ≥ 1 at baseline (n = 227), Z was superior to placebo in the BPI items ‘pain at its worst’, ‘pain at its least’, ‘pain on average’, and the Pain Severity scale at visit 4 (weeks 6–8) and visit 6 (week 12) (p < 0.05). At visit 8 (weeks 18–20) Z was superior to placebo on the ‘pain on average’ item and Pain Severity scale (p < 0.05). For visit 12 (weeks 30–32) and for LOCF Z was superior to placebo for ‘pain at its worst’, ‘pain on average’ and Pain Severity (p < 0.05 for all). For the ‘pain right now’ item there were statistically significant differences at visits 4, 6, 12 and LOCF (p < 0.05). In addition, at visit 6 (week 12), Z was superior to placebo for changes in items assessing interference with: sleep, general activities, mood, walking and enjoyment of life (p < 0.05). Z was also superior to placebo for ‘interference with general activities’ at visits 12 (weeks 30–32), 16 (weeks 42–44) and LOCF (p < 0.05). Conclusion: Results suggest Z provides significant benefit in pain reduction and Z may have an impact on patients’ daily activities which may lead to a preservation of patients’ functionality. [Table: see text]
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Santa Marinha, L., O. Nombora, M. Basto, P. Felgueiras, and A. Horta. "Sexuality among elderly patients with dementia: Are we aware of their needs?" European Psychiatry 65, S1 (June 2022): S806—S807. http://dx.doi.org/10.1192/j.eurpsy.2022.2086.

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Introduction Sexuality is one of the basic needs in human life and its positive effects for the wellbeing are undeniable. People with dementia, despite cognition and functioning impairments, still pursue intimacy as part of their expression of basic human instincts. Objectives We aim to address the subject of sexuality among patients with dementia, emphasizing the physiological, environmental and legal barriers. Methods We conduct a non-systematic review of recent evidence on dementia and sexuality, using PubMed/Medline database. Results People with dementia face several difficulties expressing their sexuality. First, they struggle with physiological barriers to enjoyment of sexuality, such as ageism, apathy and limited free mobility. Secondly, either at home or in long-term care facilities, privacy is usually abolished. For care facilities, the Sexuality Assessment Tool supports the normalization of sexuality and self-audit policies that promote resident rights for privacy and assistance. Moreover, expression of sexuality in elderly can be misinterpreted as disinhibition, leading to unnecessary use of psychotropics to cease these behaviors. Additionally, legal barriers regarding consent arise when a partner loses the ability to consent sexual activity, questioning agreement and mutual desire. The Lichtenberg and Strzepek Decision Tree for Capacity to Participate in Intimate Relationships can be helpful to address this issue. Conclusions Sexuality in older people remains neglected in clinical intervention. Besides the urgent need to deconstruct stereotypes, families and staff must be sensitized to understand the changes in expression and perception of sexuality among people with dementia, rather than being indifferent or medicate what can be perceived as disinhibited/distorted expressions of normal needs. Disclosure No significant relationships.
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