Academic literature on the topic 'Lon range contacts'

Afro-Hispanic or bozal Spanish, from the sixteenth century to the early twentieth century, exhibited numerous cases of "epenthetic" nasal consonants, exemplified by Punto Rico < Puerto Rico; limbre < libre 'free'; pincueso < pescuezo 'neck'; and monosyllabic clitics such as lon < lo(s), lan < la(s), and so on. The present study, based on a comparison of Afro-Hispanic (AH) language data from a wide range of regions and time periods, provides alternative models for spontaneous nasalization. The first involves vowel nasalization, analyzed as the linking of a free (nasal) autosegment to the first available vowel of relevant words; Spanish speakers in turn reinterpreted the nasal vowels as a nasal consonant homorganic to the preceding consonant. Cases of apparent word-final nasal epenthesis, invariably involving phrase-internal clitics, resulted from prenasalization of following word-initial obstruents, a well-documented process in Afro-Iberian linguistic contacts. The preference for voiced obstruents to pre-nasalize is attributed to the lack of the normal fricative pronunciation of /b/, /d/, and /g/ in AH speech. In general, Spanish voiced obstruents are pronounced as stops only following nasals. The stop pronunciation of Pol, /d/, and /g/ by AH speakers was reinterpreted as an additional Root node, to which a floating (nasal) autosegment could be linked. AH nasalization generally seems to stem from Africans' underspecification of Spanish vowels and consonants, resulting from the precarious conditions under which Spanish was learned by speakers of various African languages.

Territoriality in animal populations creates spatial structure that is thought to naturally buffer disease invasion. Often, however, territorial populations also include highly mobile, non-residential individuals that potentially serve as disease superspreaders. Using long-term data from the Serengeti Lion Project, we characterize the contact network structure of a territorial wildlife population and address the epidemiological impact of nomadic individuals. As expected, pride contacts are dominated by interactions with neighbouring prides and interspersed by encounters with nomads as they wander throughout the ecosystem. Yet the pride–pride network also includes occasional long-range contacts between prides, making it surprisingly small world and vulnerable to epidemics, even without nomads. While nomads increase both the local and global connectivity of the network, their epidemiological impact is marginal, particularly for diseases with short infectious periods like canine distemper virus. Thus, territoriality in Serengeti lions may be less protective and non-residents less important for disease transmission than previously considered.

The work described was aimed at an analysis of the principal factors affecting the adsorption of 60Co ions onto a peat from Lin Tao County (in the south of Gansu Province, P. R. China). The adsorption of 60Co ions onto the peat was studied as a function of contact time, ratio of solution volume (V) to solid mass (m), pH, ionic strength and the initial concentration of Co ions. It was found that the relative adsorption rate was quite rapid, that adsorption gradually decreased with increasing values of V/m and that ionic strength had a moderate effect on the process. In addition, the pH value strongly influenced the extent of adsorption. Over the high concentration range, the adsorption equilibrium could be described by the Freundlich equation, with this equation being reduced to the Henry equation, i.e. a linear adsorption isotherm, over the low concentration range. No attempt has been made at understanding the mechanism of 60Co ion adsorption onto peat in the present work.

Contact patterns in group-structured populations determine the course of infectious disease outbreaks. Network-based models have revealed important connections between group-level contact patterns and the dynamics of epidemics, but these models typically ignore heterogeneities in within-group composition. Here, we analyse a flexible mathematical model of disease transmission in a hierarchically structured wildlife population, and find that increased variation in group size reduces the epidemic threshold, making social animal populations susceptible to a broader range of pathogens. Variation in group size also increases the likelihood of an epidemic for mildly transmissible diseases, but can reduce the likelihood and expected size of an epidemic for highly transmissible diseases. Further, we introduce the concept of epidemiological effective group size , which we define to be the group size of a hypothetical population containing groups of identical size that has the same epidemic threshold as an observed population. Using data from the Serengeti Lion Project, we find that pride-living Serengeti lions are epidemiologically comparable to a homogeneous population with up to 20 per cent larger prides.

Frequency response function (FRF) data can provide considerably more information on damage in the desired frequency range as compared to modal data extracted from a very limited range around resonances. Among structural health monitoring techniques, FRF-based methods have the potential to locate structural damage. Conventional structural damage detection technology collects structural response data using contact systems, such as displacement or acceleration transducers. However, installing these contact systems can be costly in terms of labor, cost, and time. Several noncontact measurement technologies, such as optical, laser, radar, and GPS, have been developed to overcome these obstacles. Given the rapid advances in optical imaging hardware technology, the use of digital photography in structural monitoring systems has attracted considerable attention. This study develops a displacement FRF-based approach to locate damage to building structures. The proposed damage location index, CurveFRFDI, improves the sensitivity of SubFRFDI, which is a substructure FRF-based damage location index proposed by Lin et al. (2012). Moreover, the feasibility of applying the proposed approach to locate damage to building structures using displacement measured by a digital camera combined with digital image correlation techniques is also investigated in this study. A numerical example and an experimental example are presented to demonstrate the feasibility of using the proposed approach to locate damage to building structures for single and multiple nonadjacent damage locations.

Abstract A recent resurgence of interest in Old Norse linguistic borrowings in Old English has greatly expanded our knowledge of the contact situation between these two speech communities in the early medieval period and beyond. However, there are a significant number of words that have been considered borrowings in the “other” direction, i. e. from Old English to Old Norse, which have not attracted the same amount of attention in current scholarship. Much of this material requires reassessment and this paper provides a case study of two parallel compound formations in both languages – OE bærsynnig [mann]/ON bersynðugr [maðr] (‘one who is openly sinful; publican’), and OE healsbōc/ON hálsbók (‘phylactery, amulet’, lit. ‘neck-book’) – that have traditionally been considered loan translations from Old English to Old Norse with little evidence other than their formation from cognate elements. In the absence of clear-cut linguistic criteria for identifying loan translations between these two closely related languages, this paper draws on a range of literary evidence to argue for a strong likelihood of a relationship between the two compounds. Both words offer important evidence for biblical translation practices, and contribute to our knowledge about the Christianisation of Norse speaking peoples and Anglo-Norse language contact in Viking Age England.

African lions (Panthera leo) are bred in captivity on commercial farms across South Africa and often have close contact with farm staff, tourists, and other industry workers. As transmission of zoonotic diseases occurs through close proximity between wildlife and humans, these commercial captive breeding operations pose a potential risk to thousands of captive lions and to public health. An understanding of pathogens known to affect lions is needed to effectively assess the risk of disease emergence and transmission within the industry. Here, we conduct a systematic search of the academic literature, identifying 148 peer-reviewed studies, to summarize the range of pathogens and parasites known to affect African lions. A total of 63 pathogenic organisms were recorded, belonging to 35 genera across 30 taxonomic families. Over half were parasites (35, 56%), followed by viruses (17, 27%) and bacteria (11, 17%). A number of novel pathogens representing unidentified and undescribed species were also reported. Among the pathogenic inventory are species that can be transmitted from lions to other species, including humans. In addition, 83 clinical symptoms and diseases associated with these pathogens were identified. Given the risks posed by infectious diseases, this research highlights the potential public health risks associated with the captive breeding industry. We recommend that relevant authorities take imminent action to help prevent and manage the risks posed by zoonotic pathogens on lion farms.

Abstract The Pleistocene glacial period shaped the current genetic structure of numerous species. The last glacial dynamics has been proposed to have split the South American sea lion, Otaria flavescens, into two Evolutionarily Significant Units (ESUs), one on each side of the continent. However, previous studies have not provided genetic information on colonies found along 3000 km of coastline of the southernmost limit of the species distribution, where gene flow could occur. We conducted an exhaustive phylogeographical analysis of O. flavescens using a mtDNA marker, including, for the first time, data from colonies living south of latitude 45° S, in the Argentinian provinces of Santa Cruz and Tierra del Fuego. Our results indicated the presence of five Conservation Units across the distribution range of O. flavescens and suggest that the Patagonian population must have expanded about 150 000 BP. We found evidence for gene flow across the entire species range, supporting a scenario of secondary contact in Tierra del Fuego where representatives of the oldest lineages coexist. The presence of gene flow between oceans leads us to reject the assumption of complete reciprocal monophyly for mtDNA between the presumed ESUs, suggesting that the species constitutes a single Evolutionarily Significant Unit.

Fossil evidence of barnacle encrustation of vertebrate bones is reported from the middle Pleistocene Port Orford Formation of southern coastal Oregon. This material includes two associated thoracic vertebrae and a femur referable to the extinct sea lion Proterozetes ulysses that are encrusted by 1400+ individual barnacles (cf. Hesperibalanus hesperius), and a scapula of Zalophus californianus with barnacle attachment scars. In areas, the encrusting barnacles exhibit a roughly bimodal size range, and small barnacles are observed directly encrusting other larger individuals. The size, probable age, and lifespan of extant Hesperibalanus hesperius indicates a minimum period of four to seven months of seafloor exposure between decomposition and burial, although this estimate must be longer because at least two colonization events are represented. Barnacle attachment traces are identified as Anellusichnus circularis. The wide distribution of barnacles on some of these bones suggests these were regularly overturned by bottom currents, which would prevent barnacles from being smothered by prolonged contact with the sediment. Detailed study of barnacle-induced trace fossils on these specimens suggests that episkeletozoans and their traces can be useful sources of data regarding the biostratinomic history of vertebrate fossils.

Les protéines se liants aux insulateurs (IBPs) seraient impliquées dans la structuration tri-dimensionnelle des génomes en domaines topologiques (ou " TADs). Les TADs contribueraient notamment à séparer les compartiments inactifs/hétérochromatine et actifs/euchromatine. Les IBPs sont également capables de bloquer les contacts spécifiques entre les éléments activateurs ou "enhancers" d'un TAD et les promoteurs de gènes cibles présents dans un autre TAD. Ainsi, les insulateurs influenceraient l'expression des gènes selon plusieurs modes de régulations qui reste à être caractérisés à l'échelle du génome. Les résultats obtenus dans la première partie de ma thèse montrent comment les IBPs influenceraient l'expression des gènes selon un nouveau mécanisme de régulation, comme montré à l'échelle du génome de la Drosophile. Nos analyses bioinformatiques montrent que les IBPs régulent l'étalement de l'hétérochromatine répressive (H3K27me3) à la fois en cis et en trans. Les régulations en trans impliquent des boucles de chromatine entre insulateurs positionnés à la frontière de l'hétérochromatine et des insulateurs distants positionnés aux abords de gènes euchromatiniens. Ces étalements en trans conduisent à la formation de "micro-domaines" d'hétérochromatine réprimant ainsi les gènes distants. En particulier, un mutant d'insulateur qui empêche la formation de boucle diminue significativement l'établissement des micro-domaines. De plus, ces micro-domaines se formeraient au cours du développement suggérant un nouveau mécanisme insulateur-dépendant de régulation des gènes. De plus, nous un nouveau rôle de la Cohésine, un régulateur clé des boucles 3D chez l'homme, dans la régulation des ARN non codants (ncRNAs), incluant les "PROMoters uPstream Transcripts" (PROMPTs) et les enhancers RNAs (eRNAs). L'hélicase MTR4 est essentielle au contrôle de la stabilité des ARNs codants et non codants par son rôle dans les complexes nuclear-exosome targeting (NEXT) et pA-tail exosome targeting (PAXT). De manière intéressante, la déplétion de MTR4 et des sous-unités ZFC3H1 et ZCCHC8 (ou Z1 et Z8), a conduit à l'apparition de ncRNAs à l'échelle du génome. Curieusement, la cartographie des sites de liaison de MTR4 a mis en évidence que cette hélicase se lie sur des sites distants des PROMPTs. Plutôt que d'agir en cis, nos données suggèrent que la régulation des PROMPTs pourrait impliquer des contacts spécifiques à longue distance entre ces sites distants de liaison MTR4 et les promoteurs liés par Z1/Z8. Ainsi, l'intégration des données Hi-C et la détection des PROMPTS en conditions de déplétion de MTR4, Z1 ou Z8 ont souligné le rôle possible des interactions à longue distance dans la régulation des PROMPTs, depuis les sites distants MTR4. Ces travaux pourraient établir une nouvelle relation entre la structure 3D des génomes et la régulation des ARNs non codants
Insulator Binding Proteins (IBPs) could be involved in the three-dimensional folding of genomes into topological domains (or "TADs"). In particular, TADs would help to separate the inactive/heterochromatin and active/euchromatin compartments. IBPs are also able to block specific contacts between the activator or enhancer elements of one TAD and target gene promoters present in another TAD. Thus, insulators may influence gene expression according to several regulatory modes that have yet to be characterized at genome level. The results obtained in the first part of my thesis show how IBPs influence gene expression according to a new regulatory mechanism, as shown at the scale of the Drosophila genome. Our bioinformatics analyses show that IBPs regulate the spread of repressive heterochromatin (H3K27me3) both in cis and trans. Trans regulations involve chromatin loops between insulators positioned at the heterochromatin boundary and distant insulators positioned at the edges of euchromatic genes. Trans spreading leads to the formation of "micro-domains" of heterochromatin, thereby repressing distant genes. In particular, an insulator mutant that prevents loop formation significantly reduces the establishment of micro-domains. In addition, these micro-domains would be formed during development suggesting a new insulator-dependent mechanism for gene regulation. Furthermore, we could uncover a novel function of cohesion, a key regulator of 3D loops in humans, in regulating non-coding RNAs (ncRNAs), including "PROMoters uPstream Transcripts" (PROMPTs) and enhancers RNAs (eRNAs). The MTR4 helicase is essential to the control of coding and noncoding RNA stability by the human nuclear-exosome targeting (NEXT) complex and pA-tail exosome targeting (PAXT) complex. Remarkably, ncRNAs could be detected upon depletion of the Mtr4 helicase of the human NEXT complex. Moreover, depletion of additional NEXT subunits, ZFC3H1 and ZCCHC8 (or Z1 and Z8), also led to uncover ncRNAs often produced from the same loci as upon MTR4 depletion. Curiously however, mapping of Mtr4 binding sites highlighted that Mtr4 binds to sites that are distant from PROMPTs. Rather than acting in cis, our data suggest that regulation of PROMPTs could involve specific long-distance contacts between these distant MTR4 binding sites and promoters bound by Z1/Z8. As such, integration of Hi-C data together with the detection of PROMPTS upon MTR4-, Z1- or Z8- depletions highlight possible role of long-range interactions in regulating PROMPTs, from distant MTR4-bound sites. This work may establish a new relationship between the 3D structure of genomes and the regulation of ncRNAs

L’information génétique est portée par la molécule d’ADN, un polymère de nucléotides de très grande taille. Afin de mieux comprendre les mécanismes impactant le repliement de l’ADN, on peut exploiter une technique de génomique qui permet de quantifier les contacts entre régions distales du génome. Cette technique expérimentale appelée ’capture de conformation de chromosome’ (Hi-C) donne des informations quantitatives sur l’architecture et le repliement tridimensionnel des chromosomes dans le noyau. Largement utilisée chez l’Homme, la souris et la drosophile, cette technique a grandement évolué durant ces dernières années, produisant ainsi des données de qualité variable. Jusque-là étudiées à des résolutions assez grossières, notre objectif est d’étudier les données Hi-C déjà publiées à des résolutions plus fines. Pour cela, j’ai développé un outil bioinformatique, Boost-HiC, pour améliorer l’analyse des contacts chromosomiques. Fort de cette expertise, je proposerai alors une analyse comparative des structures spatiales des génomes eucaryotes, permettant de clarifier comment extraire les compartiments génomiques de manière optimale. Cette expertise sera utilisée également pour décrire le lien entre les bordures des domaines topologiques de la chromatine et la position dans le génome humain des mutations ponctuelles prédisposant au cancer
Genetic information is encoded in DNA, a huge-size nucleotidic polymer. In order to understand DNA folding mechanisms, an experimental technique is today available that quantifies distal genomic contacts. This high-throughput chromosome conformation capture technique, called Hi-C, reveals 3D chromosome folding in the nucleus. In the recent years, the Hi-C experimental protocol received many improvements through numerous studies for Human, mouse and drosophila genomes. Because most of these studies are performed at poor resolution, I propose bioinformatic methods to analyze these datasets at fine resolution. In order to do this, I present Boost-HiC, a tool that enhanced long-range contacts in Hi-C data. I will then used our extended knowledge to compare 3D folding in different species. This result provides the basis to determine the best method for obtaining genomic compartements from a chromosomal contact map. Finally, I present some other applications of our methodology to study the link between the borders of topologically associating domains and the genomic location of single-nucleotide mutations associated to cancer

In this thesis we want to create scalable, fault-tolerant and self-configuring dictionaries that can be deployed in a wide range of networks, including highly dynamic networks with frequent membership changes, like peer-to-peer overlay networks or wireless ad hoc networks. In recent years, distributed hash tables (DHTs) have emerged as a solution to implement large-scale dictionaries. However, given the existing bandwidth limitations, updating routing information in DHTs remains a challenge. Position-based routing schemes arise as an attractive solution to this problem, due to inexpensive and ubiquitous localization mechanisms. Positional information enables the creation of oblivious (or memoryless) routing schemes, where the coordinates of the current forwarding node, of its neighbors and of the destination, suffice to determine the next hop. Such routing schemes are very suitable to rapidly changing networks, because they require very little control information. We argue in this thesis that we can use positional information to efficiently support routing and DHT operation in wireless ad hoc and in wired networks, whenever position of nodes reflects network topology. To support this claim, we create and evaluate a number of algorithms that simultaneously support routing and DHT operation in both types of networks. % As an interesting result of our work, we can combine solutions into a single architecture that spans wired and wireless networks. This architecture can provide a seamless integration and use of a position-based DHT, despite the access network of the peer nodes

De nombreuses structures aéronautiques telles que les contacts aube/disque, rivet/tôle, assemblages frettés ou boulonnés subissent des endommagements de fretting fatigue dus à des sollicitations vibratoires. Ces sollicitations, qui combinent des chargements de contact de fretting (micro déplacements alternés) et de fatigue, peuvent induire des phénomènes de fissuration. L’objectif de cette thèse est d’identifier les mécanismes de propagation et d’arrêt de fissuration pour différentes configurations, impliquant des chargements de fretting et de fatigue. Différents aspects seront étudiés : - Les essais de fretting simple, fretting fatigue et fatigue seront corrélés de manière à mesurer certaines propriétés mécaniques de matériaux. Dans cette démarche, une méthode inverse permettant l’identification du seuil d’arrêt de propagation des fissures longues et courtes en fatigue à partir d’essais de fretting simple et fretting fatigue est introduite. - L’effet du rapport de charge est pris en compte afin de quantifier la fermeture de fissure pour les essais de fretting et fretting fatigue. Un nouveau modèle de fermeture sera proposé. - L’effet d’échelle est étudié grâce au développement d’une nouvelle machine de fretting fatigue permettant le suivi in situ des propagations de fissures sur des éprouvettes millimétriques. Le comportement des fissures courtes en fretting pendant un essai de fretting fatigue a été observé pour la première fois. L’idée principale de ce travail est de considérer que lors d’un essai en fretting simple, une condition d’arrêt de propagation est systématiquement atteinte. Les facteurs d’intensités de contraintes seuils en fatigue peuvent ainsi être extraits par une méthode inverse à partir des essais de fretting. La méthodologie adoptée consiste à mesurer la longueur de fissure maximale obtenue lors d’un essai de fretting correspondant à une condition d’arrêt de propagation. En jouant sur les chargements de fretting, les domaine des fissures courtes et longues sont étudiés. Pour chaque condition d’arrêt, le facteur d’intensité de contraintes seuil correspondant est calculé. Enfin, en traçant l’évolution de ce dernier en fonction de la longueur de fissure, une description complète des seuils d’arrêt de fissuration en fatigue peut être obtenue. Cette méthodologie est appliquée sur plusieurs configurations de fretting simple et est étendue aux essais de fretting fatigue. Ainsi une large gamme de rapports de charge peut être étudiée. Des essais conventionnels de fatigue propagation sur éprouvettes C(T) ont été réalisés de manière à valider complètement la démarche d’identification inverse des conditions d’arrêt de fissuration. Le manuscrit est divisé en six chapitres adoptant une évolution linéaire. Le chapitre 1 traite d’une revue bibliographique concernant la propagation des fissures courtes et longues en fatigue dans les matériaux métalliques, introduisant les phénomènes de fermeture. L’analyse est étendue à la propagation des fissures en fretting et fretting fatigue. Le chapitre 2 présente l’ensemble des techniques et méthodes expérimentales utilisées au cours de ce travail. Une analyse numérique et la méthode inverse d’identification des conditions d’arrêt de propagation sont introduites dans le chapitre 3. Les chapitres suivants traitent les différents résultats obtenus. Le chapitre 4 présente les essais de fretting simples menés sur différents matériaux métalliques. Une corrélation entre les conditions d’arrêt de fretting simple avec celles de fissures longues en fatigue est obtenue pour rapports de charge négatifs. Cette analyse est étendue aux rapports de charge positifs au chapitre 5 en couplant les essais de fretting simple, fretting précontraints et essais de fatigue C(T). Enfin, les effets d’échelle et la cinétique de propagation des fissures de fretting fatigue sont étudiés au chapitre 6
Aircraft structures such as blade/disk, rivet/sheet and fretted or bolted assembly contacts are subjected to fatigue fretting damage caused by vibratory loads. These loads combining fretting (alternating micro displacements) and fatigue contact loading can induce cracks. The objective of this thesis is to identify the propagation and crack arrest mechanisms for different configurations involving fretting and fatigue loads. Various aspects will be studied : - Simple fretting, fatigue fretting and fatigue tests will be correlated in a way to measure some material mechanical properties. A reverse approach allowing to identify the long and short fatigue crack propagation thresholds from simple fretting and fretting fatigue will be introduced. - A new closure model taking into account the effect of loading ratio on crack closure in fretting and fretting fatigue tests will be proposed. - The scaling effect will be studied thanks to the development of a new fretting fatigue machine allowing for in-situ monitoring of the propagation of small scale cracks. The behavior of fretting short cracks has been observed for the first time in a fretting fatigue test. The main idea behind the current work is the consideration that for a simple fretting test, the crack will always lead to a crack propagation arrest condition. Threshold stress intensity factors can thus be extracted from fretting tests using a reverse method. The methodology used consists in measuring the longest fretting crack corresponding to a crack propagation arrest condition. Short and long crack regimes are studied by varying fretting loads and geometries. The corresponding threshold stress intensity factor is calculated for each arrest condition. A complete description of fatigue crack arrest thresholds can be obtained from a plot depicting the evolution of the stress intensity factor range as a function of crack length. This methodology has been applied on multiple simple fretting configurations and was extended to fretting fatigue tests allowing to study a large range of loading ratios. Conventional fatigue crack propagation tests were carried out on C(T) specimens in order to validate the reverse method used for crack arrest conditions. The present thesis is divided into six main chapters. Chapter 1 provides a complete literature review on short and long crack propagation in metallic materials introducing crack closure. It provides a treatment for both fretting and fretting fatigue including a comparative analysis. Chapter 2 provides an overview of the different techniques and methodologies used as part of this research project. The reverse method used for the identification of crack propagation arrest conditions as well as a numerical analysis are presented in Chapter 3. The following Chapters provide a treatment of the various results obtained. Chapter 4 focuses on simple fretting tests carried out on different metallic materials. A correlation between simple fretting and long fatigue crack arrest conditions was obtained for negative loading ratios. This analysis is extended to positive loading ratios in Chapter 5 combining simple fretting, prestressed fretting and C(T) fatigue tests. Finally, scaling effects and fretting fatigue crack propagation kinetics are studied in Chapter 6

Tese de doutoramento em Informática, apresentada à Fac. de Ciências da Univ. de Lisboa
In this thesis we want to create scalable, fault-tolerant and self-configuring dictionaries that can be deployed in a wide range of networks, including highly dynamic networks with frequent membership changes, like peer-to-peer overlay networks or wireless ad hoc networks. In recent years, distributed hash tables (DHTs) have emerged as a solution to implement large-scale dictionaries. However, given the existing bandwidth limitations, updating routing information in DHTs remains a challenge. Position-based routing schemes arise as an attractive solution to this problem, due to inexpensive and ubiquitous localization mechanisms. Positional information enables the creation of oblivious (or memoryless) routing schemes, where the coordinates of the current forwarding node, of its neighbors and of the destination, suffice to determine the next hop. Such routing schemes are very suitable to rapidly changing networks, because they require very little control information. We argue in this thesis that we can use positional information to efficiently support routing and DHT operation in wireless ad hoc and in wired networks, whenever position of nodes reflects network topology. To support this claim, we create and evaluate a number of algorithms that simultaneously support routing and DHT operation in both types of networks.

碩士
國立中正大學
光機電整合工程所
96
Now，we use the method to make nano-template with top-down, but the method has many limits to make nano-template with top-down, so using make nano-template with bottom-up is the main stream research. And the method which make bottom-up has two method, which SAM (self-assembled monolayer) and ’SOTF’ (self-organized thin film). And, BCP has one characteristic：self-organized microphase separation, the SOTF material has advantage to making nano-template, so the thesis is probed into the possible about making nano-template with BCP-SOTF. With making nano-template, it has two challenges, one is locally control, and the other is BCP order arrange under control. The thesis has been overcome the two challenges, we use contact paint concept to do BCP locally control, and we use micro-stage to make BCP self-organized microphase separation with large range order arrange. Therefore, the concept can apply with BCP making nano-template.

The more diverse and rich a person's life is, the more areas of activity, different sides of reality he comes into contact with. People get a lot of resources from them, but at the same time each such sphere has its own vulnerability and is able to create threats to the security of people, societies and States. Most dangerous of all are the threats that affect the vital basis of human existence. These include threats to food security. They have long gone beyond biological or medical limits and received a truly geopolitical scope. The monograph shows how these threats were born and grew, as well as what can be done not only by States or international organizations, but also by individuals to minimize such threats and risks, to return to food the original meanings of the unifying principle. It is intended for specialists in the field of international relations, teachers and students of humanitarian and social disciplines, and will be of interest to a wide range of readers.

Lacertid lizards have long been a fruitful field of scientific enquiry with many people working on them over the past couple of hundred years. The scope of the field has steadily increased, beginning with taxonomy and anatomy and gradually spreading so that it includes such topics as phylogenetics, behaviour, ecology, and conservation. Since 1992, a series of symposia on lacertid lizards of the Mediterranean basin have taken place every three years. The present volume stems from the 2004 meeting in the Aeolian Islands. In the volume a wide range of island topics are considered, including the systematics of the species concerned, from both morphological and molecular viewpoints, interaction with other taxa, and conservation. The last topic is especially important, as island lizards across the world have often been vulnerable to extinction, after they came into contact with people and the animals they introduced. The volume also has papers on the more positive aspects of human influence, specifically the benign effects of traditional agriculture on at least some reptile species. Olive trees, cork oaks and the banks and walls of loose rocks that crisscross the Mediterranean scene all often contribute to elevated lizard populations. Nor is more basic biology neglected and there are articles on morphology, reproduction, development and thermoregulation. Finally, it is good to see one paper on non-Mediterranean species is included. For, to fully understand the lacertids of this region, it is necessary to appreciate their close relatives in Africa, Asia and the archipelagos of the northeastern Atlantic Ocean. (From Preface by E. Nicholas Arnold & Wolfgang Böhme)

The purpose of the monograph, which contains a modern view of the problem of adaptation of children with extremely low body weight, is to provide a wide range of doctors with basic information about the clinical picture, functional activity of innate and adaptive immunity, prognostic criteria of postnatal pathology, based on their own research. The specific features of the immunological reactivity of premature infants of various gestational ages who have developed bronchopulmonary dysplasia (BPD) and retinopathy of newborns (RN) from the moment of birth and after reaching postconceptional age (37-40 weeks) are described separately. The mechanisms of their implementation with the participation of factors of innate and adaptive immunity are considered in detail. Methods for early prediction of BPD and RN with the determination of an integral indicator and an algorithm for the management of premature infants with a high risk of postnatal complications at the stage of early rehabilitation are proposed. The information provided makes it possible to personify the treatment, preventive and rehabilitation measures in premature babies. The monograph is intended for obstetricians-gynecologists, neonatologists, pediatricians, allergists-immunologists, doctors of other specialties, residents, students of the system of continuing medical education. This work was done with financial support from the Ministry of Education and Science, grant of the President of the Russian Federation No. MK-1140.2020.7.

133 letters are edited. They range from 30 July 1770, when Charles Hutton was a schoolteacher in Newcastle, to February 1823. Most are from Hutton’s time at the Royal Military Academy in Woolwich, and shed light on his contacts, his activities, and his role as a recipient and distributor of mathematical patronage. A long series of letters illuminates his role as editor of the Ladies’ Diary and the development of his relationship with the provincial mathematician Lewis Evans. The letters range across various subjects in mathematics, natural philosophy, and civil engineering. They touch on Hutton’s personal and professional life and his various publication projects. Correspondents include the mathematicians Burrow, Playfair, and Frend, the scientists Maskelyne, Cavendish, Banks, Herschel, Baily, Laplace, and Babbage, and literary figures such as Catherine Hutton and Alexander Tilloch.

The Comparative Method in historical linguistics distinguishes resemblances among languages due to vertical transmission from those due to horizontal transmission, and from resemblances due to non-historical factors like chance. Alternative phylogenetic methods that seek long-range connections among languages have not been shown to consistently detect this distinction. Derived from the Comparative Method are the study of language contact and areal connections, lexicostatistical dating methods and linguistic-paleontological methods for reconstructing cultural knowledge. Methodological debates in historical linguistics, and application of these methods to cases in the linguistic history of the Southwest, are reviewed, suggesting that, in spite of the paucity of available data for many languages, historical linguistic methods have an important role to play in developing hypotheses about Southwestern prehistory.

This chapter begins by considering the motivations for undertaking sociolinguistic studies and discusses the range and quality of evidence that can be marshalled for early Britain. The pre-Roman linguistic situation and the advent and spread of Latin are assessed using linguistic and archaeological evidence, and the extent and nature of Latin–Celtic bilingualism across time, space, and social levels explored. A presentation of the long-standing debate on the nature of Latin spoken in Roman Britain follows, and new evidence is offered to counter the traditional view that British Latin was particularly conservative. The chapter closes by looking at the legacy of the linguistic impact of Roman Britain, briefly considering the post-Roman inscriptions and language contact phenomena in the Germanic languages.

The Hopi region is an iconic “tribal” society of the Southwest, with geographic and cultural continuity stretching back more than a millennium. The tribe has been the subject of ethnographic and archaeological study for more than 100 years, featuring a uniquely long-running dialogue with oral tradition and blurring of boundaries between ethnography and archaeology. The Hopi population stems from a combination of local groups and diverse immigrants, reflected in a social and religious organization that preserves the histories and identities of discrete clan groups. The interplay between migration and social organization recognized in ancestral Hopi sites has led to a broader re-evaluation of migration and identity across the region and in other middle-range societies. A distinctively Hopi material culture began to emerge in the early fourteenth century, and by the time of Spanish contact had crystallized into the form still visible today.

This chapter contains the essential statistical mechanics required to understand the inner workings of, and interpretation of results from, computer simulations. The microcanonical, canonical, isothermal–isobaric, semigrand and grand canonical ensembles are defined. Thermodynamic, structural, and dynamical properties of simple and complex liquids are related to appropriate functions of molecular positions and velocities. A number of important thermodynamic properties are defined in terms of fluctuations in these ensembles. The effect of the inclusion of hard constraints in the underlying potential model on the calculated properties is considered, and the addition of long-range and quantum corrections to classical simulations is presented. The extension of statistical mechanics to describe inhomogeneous systems such as the planar gas–liquid interface, fluid membranes, and liquid crystals, and its application in the simulation of these systems, are discussed.

Our hope is to enlighten and encourage those affected by aniridia and WAGR Syndrome by providing patient support and medical information. There is information to inform parents, teachers, doctors, employers, and the public about aniridia and what it is like to live with it. Several renowned doctors contribute medical chapters. Personal experiences from individuals with aniridia and parents with children with aniridia provide encouragement. Contact information for Aniridia Foundation International (AFI) is included. When a child is born without a complete iris, it is usually a symptom of a broader condition. Known as aniridia, this condition can also be a sign other parts of the eye are underdeveloped as well. Moreover, recent research shows that the gene involved can also affect the kidneys, pancreas and forebrain, so aniridia can coincide with a range of symptoms known as WAGR syndrome. Until recently, however, there was very little information available on aniridia and WAGR Syndrome. Even now, not all of the available information is current or correct, so that when a child is diagnosed with aniridia, the parents often find or are given information that is confusing and even frightening. We created this book to help those families see that they are not alone, and there are a lot of answers and a great deal of hope. It contains information about aniridia and WAGR Syndrome for parents, other family members, friends, teachers, doctors, and employers. We have been very fortunate to have several renowned doctors contribute current and comprehensive medical information that will help to provide concrete answers to basic questions and demystify these conditions. The book has many personal stories from individuals and parents that will help to give a more complete picture of what it is like to live with aniridia and WAGR Syndrome and provide encouragement and comfort. It also contains information about where to go for more answers and support, including the Aniridia Foundation International (AFI), http://www.aniridia.net, a non-profit organization created by one of the authors, Jill Nerby. We hope that you will read this book and join us in creating a better future for those with aniridia and WAGR Syndrome.

AbstractAs with most archipelagos, geography played a central role in the assembly and evolution of the endemic-rich biological communities of the Gulf of Guinea oceanic islands. The islands are located at moderate distances from the species-rich African continent that surrounds them to the east and north. This proximity facilitated colonization by many branches of the tree of life, but gene flow between the islands and continent was low enough that many lineages evolved in isolation once they reached the archipelago, resulting in many endemic species. Furthermore, several of the island taxa belong to groups typically considered to be “poor dispersers” across sea barriers, which strongly supports a role for natural rafts in seeding the islands. Oceanic currents, including the freshwater pathways that extend from large river drainages into the Gulf of Guinea during the rainy season, also support this hypothesis. The distances between the islands are equivalent to those between the islands and the continent such that inter-island dispersal events appear to be relatively rare and thus few taxa are shared between them. Still, the islands present multiple cases of secondary contact leading to hybridization and genetic introgression between closely related lineages—providing several models to study the role and consequences of gene flow in evolution. Most taxa for which molecular estimates of divergence time have been derived are much younger than the ages of the islands. This pattern is consistent with high species turnover, likely resulting from a combination of small island sizes, proximity to the African continent and a long history of intense volcanic activity. The Gulf of Guinea oceanic islands provide multiple examples of classical adaptations to island life (the “island syndrome”), including giants and dwarves, ornament and color loss, among others. In addition, emerging studies of birds are highlighting the importance of competition regimes in driving phenotypic change—with examples of both character release (low inter-specific competition) and character displacement (inter-specific competition upon secondary contact). Collectively, the Gulf of Guinea oceanic islands offer unique opportunities to study adaptation and speciation in a range of taxa and contexts.

AbstractThis study determined the spatial resolution of the virtual surface profile created by ultrasound haptic stimulation. We assumed the case where a finger moves along the surface of a virtual object. This object was produced by low-frequency lateral modulation that creates a pseudo static force. We defined the spatial resolution as the minimum distance required to discriminate between two virtual bumps. Several sensory channels are combined when a human feels the geometric features of a surface. This paper focuses on mesoscopic shapes, whose representative length ranges from a few millimeters to fingertip size. We considered two strategies to present mesoscopic shapes: changing either the contact position or the force strength. We measured the spatial resolutions in mesoscopic shapes created by each method, and discussed which factor is more effective to perceive mesoscopic features.

The purpose of the monograph, which contains a modern view of the problem of adaptation of children with extremely low body weight, is to provide a wide range of doctors with basic information about the clinical picture, functional activity of innate and adaptive immunity, prognostic criteria of postnatal pathology, based on their own research. The specific features of the immunological reactivity of premature infants of various gestational ages who have developed bronchopulmonary dysplasia (BPD) and retinopathy of newborns (RN) from the moment of birth and after reaching postconceptional age (37-40 weeks) are described separately. The mechanisms of their implementation with the participation of factors of innate and adaptive immunity are considered in detail. Methods for early prediction of BPD and RN with the determination of an integral indicator and an algorithm for the management of premature infants with a high risk of postnatal complications at the stage of early rehabilitation are proposed. The information provided makes it possible to personify the treatment, preventive and rehabilitation measures in premature babies. The monograph is intended for obstetricians-gynecologists, neonatologists, pediatricians, allergists-immunologists, doctors of other specialties, residents, students of the system of continuing medical education. This work was done with financial support from the Ministry of Education and Science, grant of the President of the Russian Federation No. MK-1140.2020.7.

The purpose of the monograph, which contains a modern view of the problem of adaptation of children with extremely low body weight, is to provide a wide range of doctors with basic information about the clinical picture, functional activity of innate and adaptive immunity, prognostic criteria of postnatal pathology, based on their own research. The specific features of the immunological reactivity of premature infants of various gestational ages who have developed bronchopulmonary dysplasia (BPD) and retinopathy of newborns (RN) from the moment of birth and after reaching postconceptional age (37-40 weeks) are described separately. The mechanisms of their implementation with the participation of factors of innate and adaptive immunity are considered in detail. Methods for early prediction of BPD and RN with the determination of an integral indicator and an algorithm for the management of premature infants with a high risk of postnatal complications at the stage of early rehabilitation are proposed. The information provided makes it possible to personify the treatment, preventive and rehabilitation measures in premature babies. The monograph is intended for obstetricians-gynecologists, neonatologists, pediatricians, allergists-immunologists, doctors of other specialties, residents, students of the system of continuing medical education. This work was done with financial support from the Ministry of Education and Science, grant of the President of the Russian Federation No. MK-1140.2020.7.

The purpose of the monograph, which contains a modern view of the problem of adaptation of children with extremely low body weight, is to provide a wide range of doctors with basic information about the clinical picture, functional activity of innate and adaptive immunity, prognostic criteria of postnatal pathology, based on their own research. The specific features of the immunological reactivity of premature infants of various gestational ages who have developed bronchopulmonary dysplasia (BPD) and retinopathy of newborns (RN) from the moment of birth and after reaching postconceptional age (37-40 weeks) are described separately. The mechanisms of their implementation with the participation of factors of innate and adaptive immunity are considered in detail. Methods for early prediction of BPD and RN with the determination of an integral indicator and an algorithm for the management of premature infants with a high risk of postnatal complications at the stage of early rehabilitation are proposed. The information provided makes it possible to personify the treatment, preventive and rehabilitation measures in premature babies. The monograph is intended for obstetricians-gynecologists, neonatologists, pediatricians, allergists-immunologists, doctors of other specialties, residents, students of the system of continuing medical education. This work was done with financial support from the Ministry of Education and Science, grant of the President of the Russian Federation No. MK-1140.2020.7.

Long-range surface plasmon (LRSP) modes have been observed on very thin metal films sandwiched between two dielectrics1 that can be excited using frustrated total internal reflection.2 The intensity profile of the light in the reflected beam contains a structure caused by interference between the light reflected from the prism base and the light being reradiated by the mode. It is possible to determine the loss coefficient of the LRSP mode from this intensity profile, and if there is an interference zero in this profile, loss coefficients caused by dissipation and reradiation can also be determined.3 A computer-controlled system that locates the plasmon resonance angle and also measures the reflectance vs angle and the intensity profile from a charge-coupled-device array was used for the data acquisition. We have measured the decay constants of several thin silver films based on the intensity profile. The results are compared with the decay constant obtained from the angular width of the plasmon resonance.

Many state-of-art microelectronic, photonic and MEMS devices are based upon or created using small-scale contacts. These include, for example, high frequency, microscale electromechanical switches and nanopatterning of organic optoelectronic materials by contact adhesion, cold welding, and lift-off. The initial stages of contact occur between asperities of micro- and/or nano-scopic dimensions. As a consequence, understanding the processes that occur at the atomic level when two rough surfaces are bought into contact is fundamentally important for a wide range of problems including adhesion, contact formation, contact resistance, materials hardness, friction, wear, and fracture. The centrality of single asperities in the fundamental micromechanical response of contact between two rough surfaces has long been recognized. A wide range of experiments has shown that the conductance of small contacts changes abruptly as a function of contact size. In some cases, the conductance through individual asperities increases in a stepwise manner as the two surfaces are pressed into contact. These jumps conductance appear to be correlated with jumps in the force. The observed force-displacement relation appears to be poorly described by JKR theory during loading, while JKR provides a reasonable description of the behavior in unloading. In this presentation (see Acta Materialia 52, 3983 (2004) for more details), we report the results of molecular dynamics simulations of single asperity contact during multiple cycles of loading and unloading at room temperature. We focus on the mechanisms by which contact deformation occurs and the relationship between contact conductance (and contact area) and the deformation. These simulations account for adhesion, elastic deformation, dislocation generation and migration, the formation of other types of defects and morphology evolution. In order to study the elastic and plastic deformation of the asperities on a rough surface, we set up a model system, as shown in Fig. 1. For simplificity, we consider a single deformable asperity on a deformable substrate that interacts with a flat, rigid plate. We calculate the conductance of the contact during loading and unloading through the modified Sharvin model [12]. To our knowledge, this study represents the first dynamic, atomistic simulation of the elastic and plastic deformation behavior of a single asperity and the corresponding evolution of the contact area and contact conductance. The present simulation results reproduce a large body of existing nano-contact experimental results, including the stepwise variation of contact area and conductance with displacement and the hysteresis in the contact radius and contact resistance versus force curves.

Automatic pain recognition is paramount for medical diagnosis and treatment. The existing works fall into three categories: assessing facial appearance changes, exploiting physiological cues, or fusing them in a multi-modal manner. However, (1) appearance changes are easily affected by subjective factors which impedes objective pain recognition. Besides, the appearance-based approaches ignore long-range spatial-temporal dependencies that are important for modeling expressions over time; (2) the physiological cues are obtained by attaching sensors on human body, which is inconvenient and uncomfortable. In this paper, we present a novel multi-task learning framework which encodes both appearance changes and physiological cues in a non-contact manner for pain recognition. The framework is able to capture both local and long-range dependencies via the proposed attention mechanism for the learned appearance representations, which are further enriched by temporally attended physiological cues (remote photoplethysmography, rPPG) that are recovered from videos in the auxiliary task. This framework is dubbed rPPG-enriched Spatio-Temporal Attention Network (rSTAN) and allows us to establish the state-of-the-art performance of non-contact pain recognition on publicly available pain databases. It demonstrates that rPPG predictions can be used as an auxiliary task to facilitate non-contact automatic pain recognition.

The Paskapoo Formation, which ranges in age from middle to upper Paleocene, is the major shallow aquifer in Alberta. This study is part of a larger GSC-led study on the potential environmental impact of hydrocarbon development in the Fox Creek area (west-central Alberta) on shallow aquifers. Fox Creek is located near the northern limit of the Paskapoo Formation. In addition to the underlying organic-rich source rocks in the study area, including the Duvernay Formation that is currently exploited for hydrocarbon resources, the Paskapoo Formation contains organic-rich intervals and coal seams. In order to investigate any potential internal hydrocarbon sources within the Paskapoo Formation, ninety-seven (97) cutting samples from the formation obtained from eight shallow monitoring wells (50-90 m) in the study area were studied for total organic carbon (TOC) content, organic matter composition and thermal maturity of coal seams using programmed pyrolysis analysis and organic petrography. The TOC content of all samples ranges from 0.2 to 8.8 wt. %, with a mean value of 0.95 ± 1.6 wt. % (n=97). The Tmax values of studied samples range from 347 to 463 °C, with a mean value of 434 ± 20 °C that suggest a range of thermal maturity from immature to peak oil window. The random reflectance (Rr) measurement and fluorescence microscopy on eighteen (18) selected samples with TOC content &amp;gt; ~1 wt. % shows a mean Rr value of 0.27% and 0.42% for the overlying till deposits and the underlying shallow depth sandstone, siltstone, shale and coal seams respectively, indicating a low rank coal ranging from lignite to sub-bituminous coal. Blue to green and yellow fluorescing liptinite macerals further confirmed the low maturity of studied samples. The low S2 yield of a large part of the samples (65%) resulted in unreliable Tmax values that overestimated the thermal maturity. Although the organic matter in the studied intervals are immature, exsudatinite, as secondary liptinite maceral, was observed in samples from the lower parts of the studied monitoring wells. Exsudatinite generally derives from the transformation of sporinite, alginite, resinite and varieties of vitrinite, which is a resinous or asphalt like material. Considering the thickness and distribution of coal seams in the studied samples, it is unlikely the exsudatinite will be a major source for aquifer hydrocarbon contamination in the study area. Additional stratigraphic studies and molecular geochemical analysis could provide an estimate of the total volume of possible organic compounds contribution to the aquifer in the study area. Due to the presence of coal seams in the studied intervals of the Paskapoo Formation, it is important to investigate the possibility of biogenic methane formation in Paskapoo shallow aquifers.

A re-evaluation of the age of the formations comprising the Eagle Plain Group of northern Yukon was necessitated by widely disparate age determinations in recent years from various authors. Maximum age estimates for the base of the group have varied from middle Albian to Cenomanian, and age estimates for the uppermost strata varied by an even greater range, from Cenomanian to late Maastrichtian. A re-examination of new and archival foraminiferal and palynological data indicates an age range of Cenomanian to late Maastrichtian for the Eagle Plain Group. The late Maastrichtian age is derived from palynology from the northeasternmost area of Eagle Plain. However, the stratigraphic relationship of these youngest beds within Eagle Plain Group remains uncertain. Marine strata of the Eagle Plain Group contain foraminiferal indices that correlate with long-established regional foraminiferal zones from the Mackenzie Delta area. The Cenomanian Zone of Trochammina superstes occurs in the Parkin and Boundary Creek formations of Eagle Plain and Mackenzie Delta, respectively. The Haplophragmoides bilobatus and overlying Glaphyrammina spirocompressa zones occur in the Burnthill Creek and Smoking Hills formations of Eagle Plain and Mackenzie Delta, respectively. Reworked microfossils are a conspicuous feature of strata within the Eagle Plain Group. The basal sandstone of the Parkin Formation, for example, contains an assemblage of foraminifera that is entirely reworked. Palynomorph assemblages through the Eagle Plain Group have been estimated at as much as 99% reworked in some strata.

Changes in climate and extreme weather are already increasing challenges for agriculture nationally and globally, and many of these impacts will continue into the future. This technical bulletin contains information and resources designed to help agricultural producers, service providers, and educators in the Midwest and Northeast regions of the United States integrate climate change considerations and action-oriented decisions into existing farm and conservation plans. An Adaptation Workbook provides producers a flexible, structured process to identify and assess climate change impacts, challenges, opportunities, and farm-level adaptation tactics and continuously evaluate adaptation actions for improving responses to extreme and uncertain conditions. A synthesis of Adaptation Strategies and Approaches serves as a “menu” of potential responses organized to provide a clear rationale for making decisions by connecting planned actions to broad adaptation concepts. Responses address both short- and long-range timeframes and extend from incremental adjustments of existing practices to major alterations that transform the entire farm operation. Example adaptation tactics—prescriptive actions for agricultural production systems common in the region—for each approach guide producers, service providers, and educators to develop appropriate responses for their farms and location. Four Adaptation Examples demonstrate how these adaptation process resources are used.

For decades, researchers have sought to understand the adhesion of ice to surfaces so that low-cost ice mitigation strategies can be developed. Presently, the field of ice adhesion is still without formal standards for performing ice adhesion tests. The U.S. Army Corps Engineers’ Research and Development Center’s Cold Regions Research and Engineering Laboratory (ERDC-CRREL) has a longstanding history as an independent third party for ice adhesion testing services. Most notably, CRREL’s Zero-Degree Cone Test (ZDCT) has been an industry favorite for more than 30 years. Despite its wide acceptance, the ZDCT contains some shortcomings, namely that freshwater ice is formed on the surface of interest within the confines of an annular gap. To address this limitation, CRREL developed and uses the Ice Adhesion Peel Test (IAPT) for testing ice adhesion. This test employs an open planar substrate from which the ice can be removed under either tensile or shear loading, thereby allowing ice to be grown directly on the target substrate without the use of molds. The IAPT configuration is therefore amenable to different ice types and geometries and will provide utility to research studies that aim to develop surface treatments to mitigate ice in a wide range of environments. This report describes the IAPT and its use for characterizing the ice adhesion properties of materials.

Goshen Valley contains extensive areas of agriculture, significant wetlands, and several small municipalities, all of which rely on both groundwater and surface water. The objective of this study is to characterize the hydrogeology and groundwater conditions in Goshen Valley and calculate a water budget for the groundwater system. Based on the geologic and hydrologic data presented in this paper, we delineate three conceptual groundwater zones. Zones are delineated based on areas of shared hydrogeologic, geochemical, and potentiometric characteristics within the larger Goshen Valley. Groundwater in Goshen Valley resides primarily in the upper basin fill aquifer unit (UBFAU) and lower carbonate aquifer unit (LCAU) hydrostratigraphic units. Most wells in Goshen Valley are completed in the UBFAU, which covers much of the valley floor. The UBFAU is the upper part of the basin fill, which is generally less than 1500 feet thick in Goshen Valley. Important spring discharge at Goshen Warm Springs issues from the LCAU. Relatively impermeable volcanic rocks (VU) occur along much of the upland parts of the southern part of Goshen Valley. Large sections of the southwest part of the Goshen Valley basin boundary have limited potential for interbasin flow. Interbasin groundwater flow is likely at several locations including the Mosida Hills and northern parts of Long Ridge and Goshen Gap in areas underlain by LCAU. Depth to groundwater in Goshen Valley ranges from at or just below the land surface to greater than 400 feet. Groundwater is within 30 feet of the land surface near and north of Goshen, in areas of irrigated pastures and wetlands that extend east toward Long Ridge and Goshen Warm Springs, and to the north towards Genola. Groundwater movement is from upland parts of the study area toward the valley floor and Utah Lake. Long-term water-level change is evident across much of Goshen Valley, with the most significant decline present in conceptual zone 2 and the southern part of conceptual zone 1. The area of maximum groundwater-level decline—over 50 feet—is centered a few miles south of Elberta in conceptual zone 2. Groundwater in Goshen Valley spans a range of chemistries that include locally high total dissolved solids and elevated nitrate and arsenic concentrations and varies from calcium-bicarbonate to sodium-chloride-type waters. Overlap in chemistry exists in surface water samples from Currant Creek, the Highline Canal, and groundwater. Stable isotopes indicate that groundwater recharges from various locations that may include local recharge, from the East Tintic Mountains, or far-traveled groundwater recharged either in Cedar Valley or east of the study area along the Wasatch Range. Dissolved gas recharge temperatures support localized recharge outside of Goshen. Most groundwater samples in Goshen Valley are old, with limited evidence of recent groundwater recharge. An annual water budget based on components of recharge and discharge yields total recharge of 32,805 acre-ft/yr and total discharge of 35,750 acre-ft/yr. Most recharge is likely from interbasin flow and lesser amounts from precipitation and infiltration of surface water. Most discharge is from well water withdrawal with minor spring discharge and groundwater evapotranspiration. Water-budget components show discharge is greater than recharge by less than 3000 acreft/yr. This deficit or change in storage is manifested as longterm water-level decline in conceptual zone 2, and to a lesser degree, in conceptual zone 1. The primary driver of discharge in conceptual zone 2 is well withdrawal. Conceptual zone 3 is broadly in balance across the various sources of recharge and discharge, and up to 1830 acre-ft/yr of water may discharge from conceptual zone 3 into Utah Lake. Minimal groundwater likely flows to Utah Lake from zones 1 or 2.

The Natural Resource Condition Assessment (NRCA) Program aims to provide documentation about the current conditions of important park natural resources through a spatially explicit, multi-disciplinary synthesis of existing scientific data and knowledge. Findings from the NRCA will help Salinas Pueblo Missions National Monument (SAPU) managers to develop near-term management priorities, engage in watershed or landscape scale partnership and education efforts, conduct park planning, and report program performance (e.g., Department of the Interior’s Strategic Plan “land health” goals, Government Performance and Results Act). The objectives of this assessment are to evaluate and report on current conditions of key park resources, to evaluate critical data and knowledge gaps, and to highlight selected existing stressors and emerging threats to resources or processes. For the purpose of this NRCA, staff from the National Park Service (NPS) and Saint Mary’s University of Minnesota – GeoSpatial Services (SMUMN GSS) identified key resources, referred to as “components” in the project. The selected components include natural resources and processes that are currently of the greatest concern to park management at SAPU. The final project framework contains nine resource components, each featuring discussions of measures, stressors, and reference conditions. This study involved reviewing existing literature and, where appropriate, analyzing data for each natural resource component in the framework to provide summaries of current condition and trends in selected resources. When possible, existing data for the established measures of each component were analyzed and compared to designated reference conditions. A weighted scoring system was applied to calculate the current condition of each component. Weighted Condition Scores, ranging from zero to one, were divided into three categories of condition: low concern, moderate concern, and significant concern. These scores help to determine the current overall condition of each resource. The discussions for each component, found in Chapter 4 of this report, represent a comprehensive summary of current available data and information for these resources, including unpublished park information and perspectives of park resource managers, and present a current condition designation when appropriate. Each component assessment was reviewed by SAPU resource managers, NPS Southern Colorado Plateau Network (SCPN) staff, or outside experts. Existing literature, short- and long-term datasets, and input from NPS and other outside agency scientists support condition designations for components in this assessment. However, in some cases, data were unavailable or insufficient for several of the measures of the featured components. In other instances, data establishing reference condition were limited or unavailable for components, making comparisons with current information inappropriate or invalid. In these cases, it was not possible to assign condition for the components. Current condition was not able to be determined for six of the ten components due to these data gaps. For those components with sufficient available data, the overall condition varied. Two components were determined to be in good condition: dark night skies and paleontological resources. However, both were at the edge of the good condition range, and any small decline in conditions could shift them into the moderate concern range. Of the components in good condition, a trend could not be assigned for paleontological resources and dark night skies is considered stable. Two components (wetland and riparian communities and viewshed) were of moderate concern, with no trend assigned for wetland and riparian communities and a stable trend for viewshed. Detailed discussion of these designations is presented in Chapters 4 and 5 of this report. Several park-wide threats and stressors influence the condition of priority resources in SAPU...

1.1 Macroeconomic summary Economic recovery has consistently outperformed the technical staff’s expectations following a steep decline in activity in the second quarter of 2020. At the same time, total and core inflation rates have fallen and remain at low levels, suggesting that a significant element of the reactivation of Colombia’s economy has been related to recovery in potential GDP. This would support the technical staff’s diagnosis of weak aggregate demand and ample excess capacity. The most recently available data on 2020 growth suggests a contraction in economic activity of 6.8%, lower than estimates from January’s Monetary Policy Report (-7.2%). High-frequency indicators suggest that economic performance was significantly more dynamic than expected in January, despite mobility restrictions and quarantine measures. This has also come amid declines in total and core inflation, the latter of which was below January projections if controlling for certain relative price changes. This suggests that the unexpected strength of recent growth contains elements of demand, and that excess capacity, while significant, could be lower than previously estimated. Nevertheless, uncertainty over the measurement of excess capacity continues to be unusually high and marked both by variations in the way different economic sectors and spending components have been affected by the pandemic, and by uneven price behavior. The size of excess capacity, and in particular the evolution of the pandemic in forthcoming quarters, constitute substantial risks to the macroeconomic forecast presented in this report. Despite the unexpected strength of the recovery, the technical staff continues to project ample excess capacity that is expected to remain on the forecast horizon, alongside core inflation that will likely remain below the target. Domestic demand remains below 2019 levels amid unusually significant uncertainty over the size of excess capacity in the economy. High national unemployment (14.6% for February 2021) reflects a loose labor market, while observed total and core inflation continue to be below 2%. Inflationary pressures from the exchange rate are expected to continue to be low, with relatively little pass-through on inflation. This would be compatible with a negative output gap. Excess productive capacity and the expectation of core inflation below the 3% target on the forecast horizon provide a basis for an expansive monetary policy posture. The technical staff’s assessment of certain shocks and their expected effects on the economy, as well as the presence of several sources of uncertainty and related assumptions about their potential macroeconomic impacts, remain a feature of this report. The coronavirus pandemic, in particular, continues to affect the public health environment, and the reopening of Colombia’s economy remains incomplete. The technical staff’s assessment is that the COVID-19 shock has affected both aggregate demand and supply, but that the impact on demand has been deeper and more persistent. Given this persistence, the central forecast accounts for a gradual tightening of the output gap in the absence of new waves of contagion, and as vaccination campaigns progress. The central forecast continues to include an expected increase of total and core inflation rates in the second quarter of 2021, alongside the lapse of the temporary price relief measures put in place in 2020. Additional COVID-19 outbreaks (of uncertain duration and intensity) represent a significant risk factor that could affect these projections. Additionally, the forecast continues to include an upward trend in sovereign risk premiums, reflected by higher levels of public debt that in the wake of the pandemic are likely to persist on the forecast horizon, even in the context of a fiscal adjustment. At the same time, the projection accounts for the shortterm effects on private domestic demand from a fiscal adjustment along the lines of the one currently being proposed by the national government. This would be compatible with a gradual recovery of private domestic demand in 2022. The size and characteristics of the fiscal adjustment that is ultimately implemented, as well as the corresponding market response, represent another source of forecast uncertainty. Newly available information offers evidence of the potential for significant changes to the macroeconomic scenario, though without altering the general diagnosis described above. The most recent data on inflation, growth, fiscal policy, and international financial conditions suggests a more dynamic economy than previously expected. However, a third wave of the pandemic has delayed the re-opening of Colombia’s economy and brought with it a deceleration in economic activity. Detailed descriptions of these considerations and subsequent changes to the macroeconomic forecast are presented below. The expected annual decline in GDP (-0.3%) in the first quarter of 2021 appears to have been less pronounced than projected in January (-4.8%). Partial closures in January to address a second wave of COVID-19 appear to have had a less significant negative impact on the economy than previously estimated. This is reflected in figures related to mobility, energy demand, industry and retail sales, foreign trade, commercial transactions from selected banks, and the national statistics agency’s (DANE) economic tracking indicator (ISE). Output is now expected to have declined annually in the first quarter by 0.3%. Private consumption likely continued to recover, registering levels somewhat above those from the previous year, while public consumption likely increased significantly. While a recovery in investment in both housing and in other buildings and structures is expected, overall investment levels in this case likely continued to be low, and gross fixed capital formation is expected to continue to show significant annual declines. Imports likely recovered to again outpace exports, though both are expected to register significant annual declines. Economic activity that outpaced projections, an increase in oil prices and other export products, and an expected increase in public spending this year account for the upward revision to the 2021 growth forecast (from 4.6% with a range between 2% and 6% in January, to 6.0% with a range between 3% and 7% in April). As a result, the output gap is expected to be smaller and to tighten more rapidly than projected in the previous report, though it is still expected to remain in negative territory on the forecast horizon. Wide forecast intervals reflect the fact that the future evolution of the COVID-19 pandemic remains a significant source of uncertainty on these projections. The delay in the recovery of economic activity as a result of the resurgence of COVID-19 in the first quarter appears to have been less significant than projected in the January report. The central forecast scenario expects this improved performance to continue in 2021 alongside increased consumer and business confidence. Low real interest rates and an active credit supply would also support this dynamic, and the overall conditions would be expected to spur a recovery in consumption and investment. Increased growth in public spending and public works based on the national government’s spending plan (Plan Financiero del Gobierno) are other factors to consider. Additionally, an expected recovery in global demand and higher projected prices for oil and coffee would further contribute to improved external revenues and would favor investment, in particular in the oil sector. Given the above, the technical staff’s 2021 growth forecast has been revised upward from 4.6% in January (range from 2% to 6%) to 6.0% in April (range from 3% to 7%). These projections account for the potential for the third wave of COVID-19 to have a larger and more persistent effect on the economy than the previous wave, while also supposing that there will not be any additional significant waves of the pandemic and that mobility restrictions will be relaxed as a result. Economic growth in 2022 is expected to be 3%, with a range between 1% and 5%. This figure would be lower than projected in the January report (3.6% with a range between 2% and 6%), due to a higher base of comparison given the upward revision to expected GDP in 2021. This forecast also takes into account the likely effects on private demand of a fiscal adjustment of the size currently being proposed by the national government, and which would come into effect in 2022. Excess in productive capacity is now expected to be lower than estimated in January but continues to be significant and affected by high levels of uncertainty, as reflected in the wide forecast intervals. The possibility of new waves of the virus (of uncertain intensity and duration) represents a significant downward risk to projected GDP growth, and is signaled by the lower limits of the ranges provided in this report. Inflation (1.51%) and inflation excluding food and regulated items (0.94%) declined in March compared to December, continuing below the 3% target. The decline in inflation in this period was below projections, explained in large part by unanticipated increases in the costs of certain foods (3.92%) and regulated items (1.52%). An increase in international food and shipping prices, increased foreign demand for beef, and specific upward pressures on perishable food supplies appear to explain a lower-than-expected deceleration in the consumer price index (CPI) for foods. An unexpected increase in regulated items prices came amid unanticipated increases in international fuel prices, on some utilities rates, and for regulated education prices. The decline in annual inflation excluding food and regulated items between December and March was in line with projections from January, though this included downward pressure from a significant reduction in telecommunications rates due to the imminent entry of a new operator. When controlling for the effects of this relative price change, inflation excluding food and regulated items exceeds levels forecast in the previous report. Within this indicator of core inflation, the CPI for goods (1.05%) accelerated due to a reversion of the effects of the VAT-free day in November, which was largely accounted for in February, and possibly by the transmission of a recent depreciation of the peso on domestic prices for certain items (electric and household appliances). For their part, services prices decelerated and showed the lowest rate of annual growth (0.89%) among the large consumer baskets in the CPI. Within the services basket, the annual change in rental prices continued to decline, while those services that continue to experience the most significant restrictions on returning to normal operations (tourism, cinemas, nightlife, etc.) continued to register significant price declines. As previously mentioned, telephone rates also fell significantly due to increased competition in the market. Total inflation is expected to continue to be affected by ample excesses in productive capacity for the remainder of 2021 and 2022, though less so than projected in January. As a result, convergence to the inflation target is now expected to be somewhat faster than estimated in the previous report, assuming the absence of significant additional outbreaks of COVID-19. The technical staff’s year-end inflation projections for 2021 and 2022 have increased, suggesting figures around 3% due largely to variation in food and regulated items prices. The projection for inflation excluding food and regulated items also increased, but remains below 3%. Price relief measures on indirect taxes implemented in 2020 are expected to lapse in the second quarter of 2021, generating a one-off effect on prices and temporarily affecting inflation excluding food and regulated items. However, indexation to low levels of past inflation, weak demand, and ample excess productive capacity are expected to keep core inflation below the target, near 2.3% at the end of 2021 (previously 2.1%). The reversion in 2021 of the effects of some price relief measures on utility rates from 2020 should lead to an increase in the CPI for regulated items in the second half of this year. Annual price changes are now expected to be higher than estimated in the January report due to an increased expected path for fuel prices and unanticipated increases in regulated education prices. The projection for the CPI for foods has increased compared to the previous report, taking into account certain factors that were not anticipated in January (a less favorable agricultural cycle, increased pressure from international prices, and transport costs). Given the above, year-end annual inflation for 2021 and 2022 is now expected to be 3% and 2.8%, respectively, which would be above projections from January (2.3% and 2,7%). For its part, expected inflation based on analyst surveys suggests year-end inflation in 2021 and 2022 of 2.8% and 3.1%, respectively. There remains significant uncertainty surrounding the inflation forecasts included in this report due to several factors: 1) the evolution of the pandemic; 2) the difficulty in evaluating the size and persistence of excess productive capacity; 3) the timing and manner in which price relief measures will lapse; and 4) the future behavior of food prices. Projected 2021 growth in foreign demand (4.4% to 5.2%) and the supposed average oil price (USD 53 to USD 61 per Brent benchmark barrel) were both revised upward. An increase in long-term international interest rates has been reflected in a depreciation of the peso and could result in relatively tighter external financial conditions for emerging market economies, including Colombia. Average growth among Colombia’s trade partners was greater than expected in the fourth quarter of 2020. This, together with a sizable fiscal stimulus approved in the United States and the onset of a massive global vaccination campaign, largely explains the projected increase in foreign demand growth in 2021. The resilience of the goods market in the face of global crisis and an expected normalization in international trade are additional factors. These considerations and the expected continuation of a gradual reduction of mobility restrictions abroad suggest that Colombia’s trade partners could grow on average by 5.2% in 2021 and around 3.4% in 2022. The improved prospects for global economic growth have led to an increase in current and expected oil prices. Production interruptions due to a heavy winter, reduced inventories, and increased supply restrictions instituted by producing countries have also contributed to the increase. Meanwhile, market forecasts and recent Federal Reserve pronouncements suggest that the benchmark interest rate in the U.S. will remain stable for the next two years. Nevertheless, a significant increase in public spending in the country has fostered expectations for greater growth and inflation, as well as increased uncertainty over the moment in which a normalization of monetary policy might begin. This has been reflected in an increase in long-term interest rates. In this context, emerging market economies in the region, including Colombia, have registered increases in sovereign risk premiums and long-term domestic interest rates, and a depreciation of local currencies against the dollar. Recent outbreaks of COVID-19 in several of these economies; limits on vaccine supply and the slow pace of immunization campaigns in some countries; a significant increase in public debt; and tensions between the United States and China, among other factors, all add to a high level of uncertainty surrounding interest rate spreads, external financing conditions, and the future performance of risk premiums. The impact that this environment could have on the exchange rate and on domestic financing conditions represent risks to the macroeconomic and monetary policy forecasts. Domestic financial conditions continue to favor recovery in economic activity. The transmission of reductions to the policy interest rate on credit rates has been significant. The banking portfolio continues to recover amid circumstances that have affected both the supply and demand for loans, and in which some credit risks have materialized. Preferential and ordinary commercial interest rates have fallen to a similar degree as the benchmark interest rate. As is generally the case, this transmission has come at a slower pace for consumer credit rates, and has been further delayed in the case of mortgage rates. Commercial credit levels stabilized above pre-pandemic levels in March, following an increase resulting from significant liquidity requirements for businesses in the second quarter of 2020. The consumer credit portfolio continued to recover and has now surpassed February 2020 levels, though overall growth in the portfolio remains low. At the same time, portfolio projections and default indicators have increased, and credit establishment earnings have come down. Despite this, credit disbursements continue to recover and solvency indicators remain well above regulatory minimums. 1.2 Monetary policy decision In its meetings in March and April the BDBR left the benchmark interest rate unchanged at 1.75%.