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1

Tashjian, Joseph. Mammographic technique for the localization of structures in small animals. Saint Paul, Minn: Science Museum of Minnesota, 1990.

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2

Tian, Xiaohua, Xinyu Tong, and Xinbing Wang. Wireless Localization Techniques. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-21178-2.

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3

C, Masdeu Joseph, and Biller José, eds. Localization in clinical neurology. 6th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2011.

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4

Patterson, Bruce K., ed. Techniques in Quantification and Localization of Gene Expression. Boston, MA: Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-1342-0.

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5

R, Trimble Michael, ed. New brain imaging techniques and psychopharmacology. Oxford: Oxford University Press, 1986.

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6

R, Trimble Michael, ed. New brain imaging techniques and psychopharmacology. Oxford: Oxford University Press, 1985.

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7

Andrea, Giorgetti, ed. Cognitive radio techniques: Spectrum sensing, interference mitigation, and localization. Boston, Mass: Artech House, 2012.

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8

Elizabeth, Hillis Argye, ed. New techniques for identifying the neural substrates of language. [Hove, East Sussex: Psychology Press, 2002.

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9

Wörz, Stefan. 3D parametric intensity models for the localization of 3D anatomical point landmarks and 3D segmentation of human vessels. Berlin: Akademische Verlagsgesellschaft Aka, 2006.

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10

Sofia, Diaz Aura, ed. The three faces of mind: Developing your mental, emotional, and behavioral intelligences. Wheaton, Ill: Theosophical Pub. House, 1996.

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11

Sofia, Diaz Aura, ed. The three faces of mind: Think, feel, and act to your highest potential. 2nd ed. Wheaton, Ill: Quest Books/Theosophical Pub. House, 2002.

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12

Sabourin, Marc. Evaluation of DNA extraction techniques for use in plasmid localization and a genomic library for Ophiostoma ulmi (Buisman) Nannf. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1993.

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13

L, Sonnier Isadore, ed. Methods and techniques of holistic education. Springfield, Ill., U.S.A: C.C. Thomas, 1985.

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14

Zhao, Ying. Localization of glutathione conjugation activities towards bromosulfophthalein in perfused rat liver: HAPV/HAHV studies with the multiple indicator dilution (MID) technique. 1993.

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15

Tong, Xinyu, Xiaohua Tian, and Xinbing Wang. Wireless Localization Techniques. Springer International Publishing AG, 2023.

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16

Localization of glutathione conjugation activities toward bromosulfophtalein in the perfused rat liver: HAPV/HAHV studies with the multiple indicator dilution (MID) technique. Ottawa: National Library of Canada, 1993.

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17

Localization Through Low Power Techniques. India: Association of Scientists, Developers and Faculties, 2014.

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18

Agarwal, Anil, Neil Borley, and Greg McLatchie. Breast surgery. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199608911.003.0005.

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This chapter provides essential information for common breast operations. Techniques of fine-needle aspiration cytology and core biopsy are described. Operations include incision and drainage of breast abscess, excision of benign breast lump, and wide local excision. Mastectomy, sentinel node biopsy, axillary clearance, and fine wire localization are described. Other operations include microdochectomy and the Hadfield–Adair procedure. Breast reconstruction operations include implant-based reconstruction, latissimus dorsi myocutaneous flap, transvers rectus abdominis myocutaneous pedicled flap (TRAM) and free TRAM, and deep inferior epigastric perforation (DIEP) free flap. Reduction mammoplasty operations described are inferior pedicle mammoplasty and medial pedicle breast reduction (Hall Findlay or Snowman technique).
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19

Patterson, B. K. Techniques in Localization of Gene Expression. Birkhauser Verlag AG, 1999.

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20

Edmunds, D. E., and W. D. Evans. Estimates for the Singular Values of −Δ‎ + q when q is Complex. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198812050.003.0012.

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This chapter considers the Schrödinger operator −Δ‎ + q with q complex. In this case the operator is not self-adjoint and so the analysis of Chapter XI does not apply. It is the distribution of the singular values that is now considered, the technique used being again the localization to cubes forming a covering of Ω‎, together with the Max–Min Principle. Some results are obtained concerning the sequence class lp to which the singular numbers and eigenvalues belong.
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21

Patterson, Bruce K. Techniques in Quantification and Localization of Gene Expression. Birkhauser, 2013.

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22

Techniques in Quantification and Localization of Gene Expression. Birkhauser, 2000.

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23

Patterson, Bruce K. Techniques in Quantification and Localization of Gene Expression. Birkhauser Verlag, 2012.

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24

Neisius, Andreas, Micheal E. Lipkin, Glenn M. Preminger, and James F. Glenn. Stone fragmentation techniques. Edited by John Reynard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0017.

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After its implementation in 1980, shock wave lithotripsy (SWL) became the first-line treatment for more than 80% of patients with urolithiasis. During the last three decades, SWL technology has advanced rapidly in terms of shock wave generation, focusing, patient coupling, and stone localization. Indications for SWL have evolved as well. Although endoscopic treatment techniques continue to improve, SWL continues to be considered first-line therapy for the treatment of many urinary stones. This chapter reviews the fundamental principles of SWL and presents advances in lithotripsy technology such as shock wave generation and focusing, advances in stone localization (imaging), different energy source concepts, and coupling modalities. Our understanding of the pathophysiology and the physics of shock waves can enhance extracorporeal SWL efficacy while limiting complications. Finally, current indications for and contraindications to SWL depending on stone location and in context of the updated AUA/EAU Guidelines are discussed.
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25

Trail, I. A., D. Temperley, and J. K. Stanley. Assessment and investigation of chronic wrist pain. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.006001.

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♦ A careful history and a thorough physical examination is of paramount importance in the diagnosis of chronic wrist pain♦ The mechanism of injury and the position of the wrist when injured is crucial information♦ The localization of swelling and local tenderness can be invaluable in diagnosis♦ Imaging of the wrist is often helpful is diagnosis, with plain radiography standard♦ Fluoroscopy, nuclear medicine, CT and MRI scans, arthrography and arthroscopy can also help with diagnosis♦ The choice of imaging technique and its interpretation depend upon clinical information derived from the history and physical examination
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26

Nobari, Ali S., and M. H. Ferri Aliabadi. Vibration-Based Techniques for Damage Detection and Localization in Engineering Structures. WORLD SCIENTIFIC (EUROPE), 2017. http://dx.doi.org/10.1142/q0145.

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27

Nobari, Ali S. Vibration-Based Techniques for Damage Detection and Localization in Engineering Structures. World Scientific Publishing Europe Ltd, 2018.

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28

Dey, Nilanjan, and Amira S. Ashour. Direction of Arrival Estimation and Localization of Multi-Speech Sources. Springer, 2017.

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29

Amin, Moeness. Radar for Indoor Monitoring: Detection, Localization, and Assessment. Taylor & Francis Group, 2017.

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30

Barreto, Armando Bennett. A spatio-temporal approach to epileptic focus localization from array electrocorticography. 1993.

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31

Al-Nahhas, Adil, and Imene Zerizer. Nuclear medicine. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0070.

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The application of nuclear medicine techniques in the diagnosis and management of rheumatological conditions relies on its ability to detect physiological and pathological changes in vivo, usually at an earlier stage compared to structural changes visualized on conventional imaging. These techniques are based on the in-vivo administration of a gamma-emitting radionuclide whose distribution can be monitored externally using a gamma camera. To guide a radionuclide to the area of interest, it is usually bound to a chemical label to form a 'radiopharmaceutical'. There are hundreds of radiopharmaceuticals in clinical use with different 'homing' mechanisms, such as 99 mTc HDP for bone scan and 99 mTc MAA for lung scan. Comparing pre- and posttherapy scans can aid in monitoring response to treatment. More recently, positron emission tomography combined with simultaneous computed tomography (PET/CT) has been introduced into clinical practice. This technique provides superb spatial resolution and anatomical localization compared to gamma-camera imaging. The most widely used PET radiopharmaceutical, flurodeoxyglucose (18F-FDG), is a fluorinated glucose analogue, which can detect hypermetabolism and has therefore been used in imaging and monitoring response to treatment of a variety of cancers as well as inflammatory conditions such as vasculitis, myopathy, and arthritides. Other PET radiopharmaceuticals targeting inflammation and activated macrophages are becoming available and could open new frontiers in PET imaging in rheumatology. Nuclear medicine procedures can also be used therapeutically. Beta-emitting radiopharmaceuticals, such as yttrium-90, invoke localized tissue damage at the site of injection and can be used in the treatment of synovitis.
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32

Albano, Giacomo. Advanced Stellar Astrology: New Forecasting Techniques, Equinoctial Stars, Precessional Eras, Localization of Events. Independently Published, 2020.

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33

Alpay, Mehmet Emin. Model-based solution techniques for the source localization problem in distributed parameter systems. 1998.

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34

Alpay, Mehmet Emin. Model-based solution techniques for the source localization problem in distributed parameter systems. 1998.

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35

Kahn, S. Lowell. Catheter Modification Techniques for Venous Sampling. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0062.

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Venous sampling is critically important in the diagnosis and localization of pituitary, parathyroid, renal, adrenal, and ovarian endocrine tumors and conditions. Catheterization of smaller veins can present a challenge and may be responsible for technical failures, particularly with adrenal vein, parathyroid, and inferior petrosal sinus venous sampling. Beyond the inherent challenges of catheterization posed by small veins, obtaining adequate blood samples can be difficult because the return of blood from a small vein may be exceedingly slow. This chapter discusses techniques to enhance the return of venous blood flow from a diagnostic catheter in a small vein. These techniques are applicable to all venous sampling, but they are particularly beneficial when sampling small-caliber veins.
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36

Benyounes, Nadia, Mauro Pepi, Roberta Esposito, Carmen Ginghina, and Ariel Cohen. Cardiac masses and potential sources of emboli. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0051.

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Cardiac masses are abnormal structures within or immediately adjacent to the heart. They have to be distinguished from variants of normal cardiac structures, postoperative changes, and ultrasound artefacts. These abnormal masses may be localized in the left or right heart cavities, with different clinical manifestations according to their localization. Among the abnormal cardiac masses (thrombus, vegetations, tumours), tumours are not discussed in this chapter. Echocardiography is the main but not the only imaging technique for the evaluation of cardiac masses, and is largely available. Hence, it is indicated in patients with a systemic embolic event, searching for a cardiac source embolism. When transthoracic echocardiography is negative, transoesophageal echocardiography is indicated, in cryptogenic ischaemic events (no cause found). Right heart masses are mainly responsible for pulmonary embolisms, but may be the cause of a systemic embolus, via the atrial septum. Right heart thrombi rarely form in situ, and are hence more often venous thrombi entrapped in the right heart on their way to the pulmonary arteries. Echocardiography is mandatory in the setting of pulmonary embolism.
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37

Gomes, William A. Neuroimaging of Epilepsy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0045.

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Neuroimaging is essential for clinical care and basic research in epilepsy. MRI is the primary tool, but adjunctive techniques are commonly employed including MRS, PET, SPECT, and MEG. These techniques facilitate localization and characterization of seizure foci prior to epilepsy surgery, and also allow preoperative assessment of risk to eloquent brain regions. Evaluation of patients with MRI-negative epilepsy remains a major clinical challenge and motivation for contemporary research.
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38

Peng, Philip W. H. Shoulder Injections: Ultrasound. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0043.

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This chapter reviews the anatomy and ultrasound-guided techniques of various shoulder injections, including the glenohumeral joints, subacromial subdeltoid bursa, long head of biceps, and acromioclavicular joint. Ultrasonography is a very useful tool allowing accurate localization of the various target structures for shoulder injections and real-time guidance of the needle insertion. A good understanding of the anatomy and sonoanatomy is of paramount importance in performing the ultrasound-guided injections.
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39

Wray, Shirley H. Eye Movement Disorders in Clinical Practice. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199921805.001.0001.

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This resource offers comprehensive instruction on the diagnosis and treatment of all varieties of eye movement disorders, and reflects the importance of correlating clinical signs of disorders in the oculomotor system with their neuroanatomic and neurophysiologic architecture. With its focus on signs and symptoms, it advances lesion localization of eye movement disorders as the central clinical concern, and presents a fresh review of bedside examination techniques in the ER, ICU, and walk-in clinic; productive ways of taking a clinical history; sign interpretation; source lesion localization; and, where appropriate, therapy. This resource is arranged according to objective signs - like ptosis, neuromuscular syndromes, dizziness, vertigo, and syndromes of the medulla - rather than disease entities, and features over 50 clinical cases, each one providing the anatomical guidance needed to make critical diagnostic and management decisions in patients who often present with abnormal eye movements.
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40

Receptors: Molecular Biology, Receptor Subclasses, Localization, and Ligand Design (Methods in Neurosciences). Academic Press, 1993.

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41

Kennard, Christopher, and Sara Ajina. Visual pathways. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199204854.003.240601_update_001.

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Visual disturbances may be caused by diseases of the optic disc, optic nerve, optic chiasm, optic tract, lateral geniculate nucleus, optic radiations, and occipital lobe of the brain, as well as other brain areas involved in complex visual processing.Diagnosis of disturbances of the visual pathways requires both knowledge of their anatomy and physiology, and the ability to carry out a thorough neuro-ophthalmological examination which should enable (1) documentation of the character and extent of the visual disturbance, and (2) topographic localization of the lesion, so that the relevant investigative techniques, such as radiological imaging, can be appropriately requested....
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42

Shils, Jay L., Sepehr Sani, Ryan Kochanski, Mena Kerolus, and Jeffrey E. Arle. Recording Techniques Related to Deep Brain Stimulation for Movement Disorders and Responsive Stimulation for Epilepsy. Edited by Donald L. Schomer and Fernando H. Lopes da Silva. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228484.003.0038.

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Neuromodulation therapies are now common treatments for a variety of medically refractory disorders, including movement disorders and epilepsy. While surgical techniques for each disorder vary, electricity is used by both for relieving symptoms. During stereotactic placement of the stimulating electrode, either deep brain stimulation electrodes or cortical strip electrodes, intraoperative neurophysiology is used to localize the target structure. This physiology includes single-unit recordings, neurostimulation evoked response evaluation, and intracranial electroencephalography (EEG) to ensure the electrode leads are in the optimal location. Because the functional target for the responsive neurostimulator is more easily visualized on preoperative magnetic resonance imaging, intraoperative physiology is used more as a confirmatory tool, in contrast to the more functional localization-based use during electrode placement for movement disorders. This chapter discusses surgical placement of the electrodes for each procedure and the physiological guidance methodology used to place the leads in the optimal location.
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43

Kar, Swarnendu. Wearable Sensor System for Providing a Personal Magnetic Field and Techniques for Horizontal Localization Utilizing the Same: United States Patent 9996162. Independently Published, 2020.

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44

Roberts, Timothy P. L., and Luke Bloy. Neuroimaging in Pediatric Psychiatric Disorders. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0060.

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Noninvasive imaging and electrophysiological techniques have been developed to probe specific aspects of brain function and dysfunction, providing exquisite spatial maps of functional centers and temporal characteristics. The evolution of these techniques has advanced from single-modality methods identifying functional localization, specialization and segregation, through real-time measures of neuronal activity, toward multimodality integration of structural, functional, and spectro-temporal approaches. While these have an immediate impact in conditions where physical brain lesions are evident (e.g., brain tumor and stroke), making a commensurate contribution within neuropsychiatry is more complex. Nonetheless, by combining concepts of morphology, neurochemistry, neural signal propagation, and regional connectivity, there appears to be ample opportunity to contribute not only to the diagnosis of patients with mental illness but to the stratification and subtyping across behavioral phenotypes and, ultimately, to patient management. Here we present an overview of the most common noninvasive neuroimaging methodologies and their applications to pediatric neurodevelopmental disorders.
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45

Berrill, Andrew, and Pawan Gupta. General principles of regional anaesthesia. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0052.

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Regional anaesthesia is now extremely safe in experienced hands. The vast majority of upper and lower limb procedures can now be performed with either a peripheral regional block alone or in combination with a general anaesthetic. Neuraxial blocks can provide reliable postoperative pain relief for operations on the trunk and lower limbs. There is no consensus on the maximum safe dose of local anaesthetics. It is important therefore to use a minimum optimal dose of a local anaesthetic for any nerve block to reduce the risk of toxicity and to improve the success rate. Adjuncts, such as clonidine and dexamethasone, can prolong the duration of the block. Advances in nerve localization methods and block needles have further improved the safety of nerve blocks. There is increasing evidence to show that ultrasound is superior to peripheral nerve stimulation for identifying nerves. Ultrasound also helps in real-time visualization of the spread of the local anaesthetic. Consent, sedation, and support from non-anaesthetic staff play a key role in the success of regional anaesthesia, especially in awake patients. Although serious complications from nerve blocks are uncommon, direct nerve injury is perhaps the most serious complication. Fortunately, these symptoms in the overwhelming majority resolve within a year. This chapter covers the history, factors affecting local anaesthetics, role of adjuncts, nerve localization techniques, and complications of regional anaesthesia. Finally, some suggestions to improve the success and safety of peripheral nerve blocks are discussed.
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46

Dyer, Paul S., Carol A. Munro, and Rosie E. Bradshaw. Fungal genetics. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0005.

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Fungi have been long used as model organisms to investigate genetic and cellular processes. An overview is provided of how fungi function at a genetic level, including ploidy, gene structure, and gene flow by sexual and asexual processes. The tools used to study fungal genetics are then described, such techniques having widespread applications in medical mycology research. Classical genetic analysis includes the use of gene mapping by sexual crossing and tetrad analysis, and forward genetic experimentation based on mutagenesis, for which various mutant screening approaches are described. Molecular genetic analysis includes gene manipulation by transformation; different methods for gene knockout and targeting, and their application for forward and reverse genetic approaches, are outlined. Finally, molecular genetic methods used to study gene expression and function are reviewed, including use of inducible or constitutive overexpression, real-time PCR, cellular localization of gene products by fluorescent tagging, and detection of protein–protein interactions.
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47

Haiman, Christopher, and David J. Hunter. Genetic Epidemiology of Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0004.

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This chapter explores the genetic epidemiology of cancer: the identification and quantification of inherited genetic factors, and their potential interaction with the environment, in the etiology of cancer in human populations. It also describes the techniques used to identify genetic variants that contribute to cancer susceptibility. It describes the older research methods for identifying the chromosomal localization of high-risk predisposing genes, such as linkage analysis within pedigrees and allele-sharing methods, as it is important to understand the foundations of the field. It also reviews the epidemiologic study designs that can be helpful in identifying low-risk alleles in candidate gene and genome-wide association studies, as well as gene–environment interactions. Finally, it describes some of the genotyping and sequencing platforms commonly employed for high-throughput genome analysis, and the concept of Mendelian randomization and how it may be useful in the study of biomarkers and environmental causes of cancer.
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48

Gupta, Pawan, and Anurag Vats. Regional anaesthesia of the lower limb. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0055.

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Lower limb nerve blocks gained popularity with the introduction of better nerve localization techniques such as peripheral nerve stimulation and ultrasound. A combination of lower limb peripheral nerve blocks can provide anaesthesia and analgesia of the entire lower limb. Lower limb blocks, as compared to central neuraxial blocks, do not affect blood pressure, can be used in sick patients, provide longer-lasting analgesia, avoid the risk of epidural haematoma or urinary retention, provide better patient satisfaction, and have acceptable success rates in experienced hands. Detailed knowledge of the relevant anatomy is essential before performing any nerve blocks in the lower limb as the nerve plexuses and the peripheral nerves are deep and obscured by bony structures and large muscles. The lumbosacral plexus provides sensory and motor innervation to the superficial tissues, muscles, and bones of the lower limb. This chapter covers different approaches and techniques for lower limb blocks, that is, the lumbar plexus, femoral nerve, fascia iliaca, saphenous nerve, sciatic nerve, popliteal nerve, ankle block, forefoot block, and the intra-articular infusion of local anaesthetics. Both peripheral nerve stimulator- and ultrasound-guided approaches are discussed. The use of ultrasound guidance is suggested as it helps in reducing the dose of local anaesthetic required and can ensure circumferential spread of local anaesthetic around peripheral nerves, which hastens the onset of block and improves success rate.
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49

Chan, Kin-Sang, Doris M. W. Tse, and Michael M. K. Sham. Dyspnoea and other respiratory symptoms in palliative care. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0082.

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Dyspnoea is prevalent among palliative care patients with increased severity over time. There are two patterns of dyspnoea-breakthrough dyspnoea and constant dyspnoea-and three separate qualities of dyspnoea-air hunger, work or effort, and tightness. The measurement of dyspnoea includes three domains: sensory-perceptual experience, affective distress, and symptom impact. The management of dyspnoea includes specific disease management, non-pharmacological intervention, pharmacological treatment, and palliative non-invasive ventilation. Cough is prevalent and disturbing in patients with cancer and chronic lung diseases, and is often associated with airway hypersecretion and impaired mucociliary clearance. Management includes specific treatments for underlying non-cancer and cancer-related causes, symptomatic treatment by antitussives, mucoactive agents, and airway clearance techniques for expectoration and reduction in mucus production. Anticholinergics may be indicated for death rattles to facilitate a peaceful death. Haemoptysis occurs in 30-60% of lung cancer patients and initial management of haemoptysis includes airway protection and volume resuscitation. Localization of the site and source of bleeding may determine the choice of treatment. If a life-threatening haemoptysis occurs, sedation should be given as soon as possible. Support should be given to the family, and debriefing provided to team members.
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