Academic literature on the topic 'Local disorder'

Introduction: while some of scholars believe that combining adult and adolescent suicidal behavior findings can result in misleading conclusions, some of researchers have stated that suicidal behavior may be a different phenomenon in adolescents than in adults. Hence, in the present study, the clinical profile of suicidal behavior among adult and child & adolescent psychiatric inpatients, has been compared with each other, to assess their resemblances or variances, in a non-western, local patient population. Methods: five acute academic wards, which have been specified for admission of first episode adult psychiatric patients, and five acute non-academic wards, which have been specified for admission of recurrent episode adult psychiatric patients, had been selected for current study. In addition, child & adolescent section of Razi psychiatric hospital was the field of appraisal concerning its specific age-group. All inpatients with suicidal behavior (successful suicide and attempted suicide, in total), during the last five years (2013-2018), had been included in the present investigation. Besides, clinical diagnosis was based on Diagnostic and Statistical Manual of Mental Disorders, 5th edition. Intra-group and between-group analyses had been performed by ‘comparison of proportions’. Statistical significance as well, had been defined as p value ≤0.05. Results: As said by results, during a sixty months period, sixty-three suicidal behaviors among adult patients, including one successful suicide and sixty-two suicide attempts, and fourteen suicide attempts among child & adolescent patients, without any successful one, had been recorded by the security board of the hospital. While among adults and child & adolescent patients no significant gender-based difference was evident, with respect to suicidal conduct, among adults, the most frequent mental illness was bipolar I disorder, which was significantly more prevalent in comparison with other mental disorders. The other disorders included schizophrenia, major depressive disorder, personality disorders (borderline & antisocial), substance abuse disorders, and adjustment disorder. Among child & adolescent subjects, the most frequent mental illness was, once more, bipolar I disorder, followed by conduct disorder, and substance abuse disorder. Moreover, no significant difference was evident between the first admission and recurrent admission cases in adults or child & adolescents. While self-mutilation, self poisoning and hanging were the preferred methods of suicide among both groups, self-mutilation was significantly more prevalent than the other ways. Conclusion: While the annual incidence of suicidal behavior in inpatient adults and child & adolescents was comparable, bipolar disorder was the most frequent serious mental illness among suicidal subjects of both groups. Moreover, self-mutilation was the preferred method of suicide in adult and child & adolescent psychiatric inpatients.

The spin-disorder resistivity (SDR) of a broad range of magneticmaterials, both ordered and disordered, is reviewed.We identify the SDR at the critical temperature with the residualresistivity of the corresponding system evaluated in the frameworkof the disordered local moment (DLM) model.The underlying electronic structure is determined in the frameworkof the tight-binding linear muffin-tin orbital method which employsthe coherent potential approximation to describe the DLM stateand chemical disorder.The DLM fixed-spin moment method is used in the case when the DLMmoment collapses.The Kubo-Greenwood approach is employed to estimate the resistivityof the DLM state.Formalism is applied to Fe and Ni and its alloys, Heusler alloys,and ordered ferromagnetic and antiferromagnetic alloys.Finally, the SDR of the Earth's core will be studied using thesame formalism.Calculations are compared with available experimental data.

The purpose of this study was to examine a behavioral index of hemispheric asymmetry (i.e., visual hierarchical attention) in posttraumatic stress disorder (PTSD), a disorder characterized by anxiety and other emotional symptoms. A reaction time based, computerized, global–local visual paradigm was administered to 26 PTSD-diagnosed and 22 psychopathology-free right-handed, male Vietnam War zone veterans. Results indicated that PTSD-diagnosed veterans displayed slower reaction times to all targets than the no-mental disorders comparison sample. However, findings also revealed a Group × Target location interaction in which the PTSD group was slower than the no-disorders comparison sample to respond to local, but not global, targets. Moreover, relative global bias was greater among PTSD-diagnosed veterans than their no-diagnosis counterparts. Findings provide partial support for the hypothesis that PTSD may be associated with a functional cerebral asymmetry favoring the right hemisphere. (JINS, 2004,10, 709–718.)

Aims and Objectives: To determine the frequency of Neurological Disorders, Misdiagnosed as Conversion Disorder in our local population Study Design: Cross sectional study Place and Duration of Study: Study was conducted at Psychiatry Department, Akhtar Saeed Medical College & Hospital, Lahore Pakistan, from June, 2021 to December, 2021. Data Collection: After meeting the inclusion criteria 115 patients were enrolled. CT brain, MRI brain and EEG were carried out to assess neurological symptoms in patients admitted with a diagnosis of conversion disorder. Misdiagnosis was labeled as per operational definition. All the data analyzed on SPSS version 23. Results: In this study the mean age was (27.03±11.95) years, male to female ratio was 0.36:1. The CT and MRI diagnosed abnormal finding in 7(6.1%) patients, while EEG was abnormal in 2(1.7%) of these 7 patients, resulting in neurological disorders being diagnosed in 7(6.1%) patients. Hence, in this study misdiagnosed cases were 7(6.1%). Conclusion: This study concluded that frequency of Neurological Disorders Misdiagnosed as Conversion Disorder is 6.09% in our local population. Keywords: Conversion Disorder, Neurological disorder, EEG, MRI, CT

Introduction: Behavioral and cognitive dysfunction is frequently observed in patients with recurrent seizures and represents an important challenge in treating these patients. In the present assessment the incidence and clinical profile of seizure attacks have been probed among a great sample of non-western psychiatric inpatients and compared with the available data in literature regarding prevalence and other associated clinical physiognomies Methods: All inpatients that had suffered seizure attack during the last sixty-four months had been included in the present study. Clinical diagnosis, as well, was in essence based on Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5). Results: While epilepsy had been identified as the primary cause of seizure (82.92%), 17.64% of them had experienced their first attacks during hospitalization. Annual incidence of seizure in psychiatric iseizure; epilepsy; schizophrenia; mood disorder; neuropsychiatry.npatients, on the whole, was around 0.07%. It was almost 0.06 in identified epileptic cases and about 0.01% with respect to the first time unprovoked epileptic attack. Also, the seizure attacks were significantly more prevalent among male psychiatric inpatients than female patients. Schizophrenia and bipolar disorder were significantly more prevalent than substance abuse, schizoaffective and depression, as comorbid psychiatric disorders among patients who had suffered seizure attacks, generally, and known cases of epilepsy, particularly. Conclusion: While, etiologically, epilepsy had been identified as the primary cause of seizure in psychiatric inpatients, schizophrenia and bipolar disorder were significantly more prevalent, as comorbid psychiatric disorders, in comparison with other primary psychiatric illnesses. Male gender, as well, could be considered as a risk factor.

SummaryAims – To define the prevalence of mental disorder within an Italian local jail and to describe main psychiatric treatments provided. Methods – Cross-sectional study of consecutive male prisoners referred, over a twenty-month period, for a clinical psychiatric assessment, among population (N=990) of Casa circondariale “Torre del Gallo”, Pavia (I); clinical DSM-IV diagnostic assessment and retrospective analysis of provided psychiatric treatments (i.e. psychiatric visits and pharmacological prescriptions). Results – 191 men (19.3%) had one or more current mental disorders (excluding substance misuse), including 13 (1.3%) psychosis; 53 (5.4%) mood disorder; 24 (2.4%) anxiety disorder; 26 (2.6%) adjustment disorder; 40 (4.1%) personality disorder; 32 (3.2%) personality disorder plus mood disorder; 3 (0.3%) mental retardation. Substance- (N=89, 47%) and HIV-related (N=19, 10%) disorders comorbidity is recognised. Psychiatric visits are mainly provided to psychosis and personality disorder plus mood disorder subgroups. Off-label antipsychotics prescriptions are frequent. Conclusions – The prevalence of mental disorder in this population is higher than US and EU averages, and for particular diagnostic subgroups it could be underestimated. Psychiatric management in prison should be reorganized according to national and European health guidelines.

In recent years, doped ceria compounds have attracted increasing attention as electrolytes for application in Solid Oxide Fuel Cell devices, thanks to their high performance at intermediate temperature. In cerium oxide, ionic conductivity is driven by the presence of oxygen vacancies, introduced for charge balance after doping with a lower valent cation. With increasing doping concentration the oxygen diffusion is impeded, probably because of the formation of aggregates that trap oxygen vacancies. Their nature is though still under debate. Owing to the close interplay between transport properties and local structure, an accurate description of the defects on the atomic scale is of the utmost importance for understanding the mechanisms at work in doped ceria. In this study we propose to unveil the complex disorder in doped ceria with a combined powder diffraction study. On the one hand, X-ray and Neutron powder diffraction are joint to couple their potentialities; on the other hand, two different crystallographic approaches are exploited. The conventional crystallographic methods allow to study the long range structure modifications that occur with doping. The Pair Distribution Function is instead employed to study the local structure, in terms of deviations from the long range atomic ordering. The goal of the thesis is to provide a crystallographic description of the atomic rearrangements induced by doping, looking for a relationship between the local structure and the transport properties.

Background – Previous reports of abnormal auditory N2 and P3 event-related potentials (ERPs) suggest impaired discrimination, evaluation or context updating for infrequent target stimuli in post-traumatic stress disorder (PTSD). This study examines each of these processes by investigating high-resolution ERP topography during target detection for visual word stimuli. Method – ERPs were recorded at 124 electrodes from 10 PTSD patients and 10 matched controls. Target detection tasks comprised blocks of equally probable red and blue words, with low probability target events. Detection of fixed target words in one color provided the basis for measurement of selective attention for color, stimulus evaluation and target detection processing. Alternative task instructions, with the same stimuli, required detection of any consecutive word repeats in an attended color, which demands working memory updating for nontarget words. Comparison of attended non-target words from each task indicates the extra activity for updating working memory representations of target attributes. Thus, specific condition comparisons provide measures of stimulus discrimination and evaluation, working memory updating and target detection. Results – PTSD patients had slower and less accurate motor responses in both tasks, with greater inaccuracy during the variable target task. There was abnormal ERP activity in PTSD at 200-300 ms in the left posterior temporal region during stimulus discrimination and target recognition. During evaluation of attended non-target words, PTSD patients demonstrate deficits in frontal and parietal regions at 400-500 ms. During working memory updating, at 400-600 ms, there was a delay in frontal activation, followed by smaller activity in parietal areas in PTSD. During target word recognition, PTSD patients demonstrate deficits in frontal activity, with greater occipital and parietal activity. Conclusions – These findings indicate impaired evaluation and integration of new information in working memory. In particular, the results suggest failure in frontal executive systems, with greater dependence on visual processing for effective target detection. The current findings are consistent with neuropsychology studies that identify deficits of attention and memory for verbal information in PTSD. This study provides insight into the temporal components of attention and working memory in PTSD. It is proposed that working memory deficits arise from disruption to synchronized activity in distributed networks engaged in working memory processes.

We illustrate self-assembly with several systems which aim to harness the process of assembly to create new functional structures. The concept of kinetic trapping preventing assembly and the importance of reversibility, breaking as well as making bonds, for avoiding such traps are introduced. We aim to identify how reversible systems are, with the aim of aecting the prediction, control and design of new systems. In four systems a lattice gas model, and three models based upon patchy particle schemes, a yield is dened and used to identify optimal assembly at a given time. Three measurements relevant to reversibility are described, applied, and compared with the results of similar studies. The rst simply counts the bonding and un-bonding events, or kinks, over the whole assembly process and compares the total number of events with the net bonding events. We measure values of 100 􀀀 1000kinks per bond in crystal systems, and 60 􀀀 200 for closed structures. In analogy with a toy model the values can be related to a `forgivingness', a ratio of bad bonding sites, to good ones. We then turn to measurements at early times which allow for the prediction of when assembly will occur. These include rate measurements of kinks which provide an instant measure of reversibility and comparison of correlation and response functions with the equilibrium uctuation dissipation theory. These methods examine the dynamics of the assembly process while our third approach examines the structures during assembly. We examine how each of the measurements provide information about the assembly process and how it relates to the particles, their interactions and the nal structure. The possibility of using the methods in combination is shown to be relevant to the prediction of assembly and how they might be used to implement design and control schemes to improve assembly.

Visuospatial abilities are considered essential to our interaction with the environment and are involved in many every-day activities (Hegarty & Waller, 2005; Jansen, Wiedenbauer, & Hahn, 2010). A useful way to approach this neuropsychological domain is the global-local paradigm, according to which, people may attend an event using a global processing style, in which they consider the gestalt of a set of stimuli, or a local processing style, in which they focus on details (Förster & Dannenberg, 2010; Navon, 1977; Schooler, 2002). An abundance of research on global versus local processing has revealed preferential processing styles (with a global or local bias) in specific neurodevelopmental disorders, particularly as concerns Autism Spectrum Disorders (ASD) (Caron, Mottron, Dawson, Bertiaume, & Dawson, 2006; Kuschner, Bodner, & Minshew, 2009). Conflicting findings have often emerged in the literature (see for example Van der Hallen, Evers, Brewaeys, Van den Noortgate, & Wagemans, 2015), however, showing that participants with different developmental disorders can process both global and local information, depending on the task requirements and the cognitive domain involved, but in different and atypical ways (Dukette & Stiles, 2001). These results prevent possible generalizations and need to be further explored. Differently, global and local processing styles have never been studied in children with other neurodevelopmental disorders, such as Nonverbal Learning Disabilities (NLD), even though there is evidence to suggest that the issue could be relevant in individuals with NLD as well (Chow & Skuy, 1999). For this reason, cross-task and cross-syndrome comparisons are suggested as the best way to analyze these processing abilities and reveal similarities and differences in global and local processing styles in neurodevelopmental disorders (D’Souza, Booth, Connolly, Happé, & Karmiloff-Smith, 2016). The main aim of this PhD dissertation is to improve our understanding of the role of global and local visuospatial processing in the neuropsychological profile of specific neurodevelopmental disorders, using cross-task and cross-disorder comparisons. Children with ASD without intellectual disability (ID) or NLD were tested in terms of their performance in different domains of visuospatial skills, comparing them with each other and with children who had other neurodevelopmental disorders, such as dyslexia or Attention Deficit Hyperactivity Disorder (ADHD). The assessment focused on visuospatial processing speed, visuo-perceptual and visuo-constructive abilities, visuospatial working memory (VSWM), and their interplay with local and global processing. Based on the modified Block Design Task (BDT) paradigm (Caron et al., 2006), new tasks and stimuli have been devised in order to assess the previously mentioned visuospatial abilities, and four studies have been carried out. Study I aimed to make a cross-task comparison on global-local visuospatial processing in two groups of participants with ASD without ID – with and without a visuospatial peak (–P and –NP) – comparing them with matched typically developing (TD) individuals. The results helped us to clarify the visuospatial profile of the two groups of individuals with ASD, demonstrating the importance of taking specific factors into account (i.e. the visuospatial domains examined and the perceptual reasoning abilities). Participants with ASD-NP performed poorly in all domains, revealing weaker spatial integration abilities in the visuo-perceptual domain and a diminished sensitivity to perceptual coherence in the VSWM, while the ASD-P group used both global and local processing effectively according to the task, and a local bias only emerged in the visuo-constructive task. In agreement with D’Souza and coauthors (2016), our results support the conviction that labelling individuals with ASD as ‘local processors’ is restrictive. They may use both local and global processing styles depending on the demands of the task in hand, the visuospatial domain involved and their cognitive visuospatial functioning. Study II (Chapter 3) aimed to investigate global and local visuospatial processing in children with symptoms of NLD comparing them with children with symptoms of dyslexia and with TD controls. The results showed that children with symptoms of NLD were less accurate in visuo-constructive tasks, while children with symptoms of dyslexia were only slightly impaired in a visuo-constructive task, but clearly slower in the perceptual task. Children with symptoms of NLD were less able to benefit from different levels of coherence of the stimuli, probably as a consequence of their less flexible and efficient visuospatial processes (Mammarella, & Cornoldi, 2005). In particular, the global dominance mechanism (Navon, 1977) made it more complicated for the group with symptoms of NLD to switch from a global to a local processing, which was needed to complete the visuo-constructive task correctly. After investigating the issue of global and local visuospatial processing separately for ASD without ID and NLD, the aim of Study III (Chapter 4) was to draw a cross-disorders comparison, highlighting similarities and differences across three clinical profiles - ASD without ID, NLD and ADHD - as compared with TD controls. Our results revealed different visuospatial profiles for the groups considered, and suggested the utility of manipulating the coherence of stimuli to investigate visuospatial skills. Marked deficit in all the visuospatial domains emerged for the group with NLD, confirming that impairments in the visuospatial domain are core and distinctive symptoms of this disorder (Cornoldi, Mammarella, & Fine, 2016; Semrud-Clikeman, Walkowiak, Wilkinson, & Christopher, 2010). In addition, difficulty in integrating local configurations in a coherent whole emerged for the visuo-perceptual domain. A heterogeneous profile emerged for children with ADHD, which showed, consistently with previous studies, impairment in the visuospatial processing speed domain and in VSWM (Martinussen, Hayden, Hogg-Johnson, & Tannock, 2005; Weigard & Huang-Pollock, 2017). Moreover, these participants presented some difficulties in visuo-constructive abilities when they had to deal with global configurations, while they performed normally in visuo-perceptual task. Differently, participants with ASD performed normally in all the examined domains, using effectively both global and local visuospatial processes, with the sole exception of the visuo-constructive task in which this group showed slower response times and a diminished sensitivity to perceptual coherence (Caron et al., 2006; Shah & Frith, 1993). Finally, since individuals with NLD and those with High Functioning Autism or Asperger Syndrome (DSM-IV TR, American Psychiatric Association [APA], 2000) are often confused, Study IV (Chapter 5) included a further comparison between ASD and NLD. Visuo-constructive abilities and VSWM were investigated in a subgroup of participants with ASD without ID and without a visuospatial peak (ASD-NP) and in a group with NLD. Thus, Study IV aimed to analyze whether ASD-NP – though not representative of the ASD without ID population as a whole– shared any characteristics with the NLD group. Once again, our results differentiate the visuospatial profile of children with NLD from that of children with ASD. The former group showed an impaired performance in all the domains examined affecting both global and local levels of processing. The ASD group had a more heterogeneous profile, with normal performance in VSWM and in the drawing of a complex figure, slower response times in the segmented condition of visuoconstructive BDT and a more local and fragmented drawing style in the recall of a complex figure. Here again, local bias affected the performance of participants with ASD in tasks demanding visuoconstructive skills that specifically involved combining parts to form a single whole (Simic, Khan, & Rovet, 2013). General conclusions derived from the main findings of the four studies, and both clinical and educational implications will be thus highlighted in the final chapter of this dissertation. To conclude, investigating visuospatial abilities and global-local processing in individuals with neurodevelopmental disorders offer crucial insight for the analysis of the strengths and weaknesses of the clinical profiles examined and for their differential diagnosis. There is still space for further research on the domains of visuospatial abilities, and on the general neuropsychological functioning of children with different neurodevelopmental disorders. This dissertation was an effort to raise and clarify some points, however other questions remain open and will require further studies.
Le abilità visuospaziali sono un insieme di abilità considerate essenziali nell’interazione con l’ambiente e sono coinvolte in numerose attività quotidiane (Hegarty & Waller, 2005; Jansen, Wiedenbauer, & Hahn, 2010). Il paradigma di elaborazione globale-locale (Navon, 1977) costituisce un utile approccio per studiare questo dominio neuropsicologico. Secondo tale paradigma le persone possono percepire un evento usando uno stile di elaborazione globale, per cui considerano la gestalt di un insieme di stimoli, o uno stile di elaborazione locale, per cui si focalizzano sui dettagli (Förster & Dannenberg, 2010; Navon, 1977; Schooler, 2002). Numerose ricerche sull’elaborazione globale-locale hanno rivelato l’uso preferenziale di uno stile di elaborazione (con un bias globale o locale) in specifici disturbi del neurosviluppo, in particolare riguardo al disturbo dello spettro dell’autismo (ASD) (Caron, Mottron, Dawson, Bertiaume, & Dawson, 2006; Kuschner, Bodner, & Minshew, 2009). Tuttavia, risultati conflittuali sono spesso emersi in letteratura (vedi Van der Hallen, Evers, Brewaeys, Van den Noortgate, & Wagemans, 2015) e mostrano come i partecipanti con differenti disturbi dello sviluppo possono elaborare sia informazioni locali che globali, a seconda delle richieste del compito e del dominio cognitivo coinvolto, ma in modi differenti e atipici (Dukette & Stiles, 2001). Questi risultati prevengono possibili generalizzazioni e necessitano di essere ulteriormente esplorati. Al contrario, gli stili di elaborazione globale-locale non sono mai stati studiati in bambini con altri disturbi del neurosviluppo, come il disturbo dell’apprendimento nonverbale (NLD), nonostante evidenze abbiano suggerito che questi aspetti possano essere rilevanti anche nell’NLD (Chow & Skuy, 1999). Per tale ragione, confronti tra differenti disturbi del neurosviluppo e attraverso l’uso di diversi compiti vengono suggeriti come il metodo migliore per analizzare queste abilità ed evidenziare similitudini o differenze nell’uso degli stili di elaborazione (D’Souza, Booth, Connolly, Happé, & Karmiloff-Smith, 2016). L'obiettivo principale della presente tesi di Dottorato è quello di migliorare la nostra comprensione del ruolo dell’elaborazione visuospaziale globale-locale nel profilo neuropsicologico di specifici disturbi del neurosviluppo, attraverso la comparazione di diversi disturbi e l’uso di prove differenti. Sono state indagate le prestazioni di partecipanti con ASD senza disabilità intellettiva (ID) o NLD in diversi domini di abilità visuospaziali, confrontandoli tra loro e con bambini aventi altri disturbi del neurosviluppo, come la dislessia o il deficit di attenzione/iperattività (ADHD). L’assessment si è concentrato sull’indagine della velocità di elaborazione visuospaziale, delle abilità visuo-percettive, visuo-costruttive e di memoria di lavoro visuospaziale (VSWM). È stata inoltre indagata l’interazione tra le performance in questi domini e l'elaborazione globale-locale. Sulla base del paradigma modificato di disegno con cubi (BDT) (Caron et al., 2006), sono stati elaborati nuovi compiti e stimoli per valutare le abilità visuospaziali menzionate. In particolare, sono stati condotti quattro studi. Lo Studio I ha indagato gli stili di elaborazione visuospaziale globale-locale in due gruppi di partecipanti con ASD senza ID - con e senza un picco visuospaziale (-P e -NP) - confrontandoli con individui a sviluppo tipico (TD). I risultati hanno permesso di chiarire il profilo visuospaziale dei due gruppi di partecipanti con ASD, dimostrando l’importanza di tenere in considerazione fattori specifici (come i domini di abilità visuospaziali esaminati e le abilità di ragionamento percettivo dei partecipanti). I partecipanti con ASD-NP hanno ottenuto scarsi risultati in tutti i domini, mostrando inferiori capacità di integrazione spaziale nel dominio visuo-percettivo e una ridotta sensibilità alla coerenza percettiva nella VSWM, mentre il gruppo ASD-P ha utilizzato entrambe le strategie di elaborazione globale e locale in modo efficace in base al compito e un bias locale è emerso solo nel compito visuo-costruttivo. In accordo con D'Souza et al. (2016), i nostri risultati sostengono la convinzione che etichettare gli individui con ASD come "local processors" sia restrittivo. Infatti, essi possono utilizzare entrambi gli stili di elaborazione locale e globale a seconda delle richieste del compito, del dominio visuospaziale coinvolto e del loro funzionamento cognitivo di tipo visuospaziale. Lo studio II (Capitolo 3) ha indagato l'elaborazione visuospaziale globale-locale nei bambini con sintomi di NLD confrontandoli con bambini con sintomi di dislessia e con TD. I risultati hanno mostrato un’accuratezza inferiore per i bambini con sintomi di NLD nel compito visuo-costruttivo, mentre i bambini con sintomi di dislessia hanno mostrato lievi difficoltà nel compito visuo-costruttivo e una chiara lentezza in quello viuso-percettivo. Inoltre, i bambini con sintomi di NLD si sono mostrati meno in grado di beneficiare dei diversi livelli di coerenza degli stimoli, probabilmente come conseguenza dei loro processi visuospaziali meno flessibili ed efficienti (Mammarella & Cornoldi, 2005). In particolare, il meccanismo di dominanza globale (Navon, 1977) ha reso più complicato per il gruppo con sintomi di NLD il passaggio dall’elaborazione globale a quella locale, necessario per completare correttamente il compito visuo-costruttivo. Dopo aver esaminato l’elaborazione visuospaziale globale-locale separatamente per ASD senza ID e NLD, lo scopo dello Studio III (Capitolo 4) era quello di effettuare un confronto tra disturbi, evidenziando somiglianze e differenze tra tre profili clinici - ASD senza ID, NLD e ADHD - rispetto ai TD. I nostri risultati hanno rivelato diversi profili visuospaziali per i gruppi considerati e suggerito l'utilità di manipolare la coerenza degli stimoli per l’indagine di tali abilità. Per il gruppo con NLD è emerso un deficit marcato in tutti i domini visuospaziali, a conferma che le difficoltà in tale dominio costituiscono sintomi fondamentali e distintivi di questo disturbo (Cornoldi, Mammarella & Fine, 2016, Semrud-Clikeman, Walkowiak, Wilkinson e Christopher, 2010). Inoltre, per il dominio visuo-percettivo è emersa la difficoltà di integrare le configurazioni locali in un insieme coerente. Per il gruppo con ADHD si è evidenziato un profilo eterogeneo, i partecipanti con tale diagnosi hanno mostrato, in linea con gli studi precedenti, un deficit nel dominio di velocità di elaborazione visuospaziale e nella VSWM (Martinussen, Hayden, Hogg-Johnson & Tannock, 2005, Weigard & Huang-Pollock, 2017). Inoltre, questi partecipanti hanno presentato alcune difficoltà nelle abilità viso-costruttive quando dovevano ricostruire configurazioni globali, mentre sono emerse abilità visuo-percettive in norma. Diversamente, i partecipanti con ASD hanno mostrato prestazioni in norma in tutti i domini esaminati, utilizzando efficacemente processi visuospaziali globali e locali, con l'unica eccezione del compito visuo-costruttivo in cui questo gruppo ha mostrato tempi di risposta più lenti e una sensibilità ridotta alla coerenza percettiva (Caron et al., 2006; Shah & Frith, 1993). Infine, considerato che i profili di individui con NLD e con autismo ad alto funzionamento o sindrome di Asperger (DSM-IV TR, American Psychiatric Association [APA], 2000) sono spesso confusi, nello Studio IV (Capitolo 5) è stato proposto un ulteriore confronto tra ASD e NLD. Le abilità visuo-costruttive e la VSWM sono state studiate in un sottogruppo di partecipanti con ASD senza ID e senza picco visuospaziale (ASD-NP) e in partecipanti con NLD. Lo scopo era quello di analizzare se il gruppo con ASD-NP - sebbene non rappresentativo dell'intera popolazione con ASD senza ID – condividesse o meno caratteristiche con il gruppo NLD. Ancora una volta, i nostri risultati hanno permesso di differenziare il profilo visuospaziale dei bambini con NLD da quello dei bambini con ASD. Il primo gruppo ha mostrato prestazioni deficitarie in tutti i domini esaminati sia per il livello di elaborazione locale sia per quello globale. Il gruppo con ASD ha mostrato invece un profilo più eterogeneo, con prestazioni in norma nella VSWM e nel disegno di una figura complessa, tempi di risposta più lenti nella condizione segmentata della prova visuo-costruttiva e uno stile di disegno locale e frammentato nel disegno a memoria di una figura complessa. Anche qui, il bias locale ha influenzato le prestazioni dei partecipanti con ASD in compiti che richiedevano competenze visuo-costruttive e nello specifico di combinare le parti per formare un unico insieme (Simic, Khan, & Rovet, 2013). Infine, le conclusioni generali derivate dai principali risultati dei quattro studi e le loro implicazioni cliniche ed educative sono state evidenziate nel capitolo conclusivo della presente tesi. Per concludere, l'analisi delle capacità visuospaziali e l'elaborazione globale-locale in individui con disturbi del neurosviluppo offrono una visione cruciale per l'analisi dei punti di forza e di debolezza dei profili clinici esaminati e per la loro diagnosi differenziale. C'è ancora molto spazio per ulteriori ricerche sulle capacità visuospaziali e sul funzionamento neuropsicologico generale dei bambini con diversi disturbi del neurosviluppo. La presente tesi ha avuto l’obiettivo di sollevare e chiarire alcuni punti, ma altre domande restano aperte e richiederanno ulteriori studi.

In this paper we have obtained expression for the contribution to DOS with the help of the method of the temperature Green functions. Multiple elastic electron scattering by impurities and structural inhomogeneities in graphene on a substrate, has been taken into account. The resulting expression for the contribution to DOS depends on temperature, concentration of impurities and the type of short-range order (structural heterogeneity). When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/35212

Concomitantly with lattice disorder, there is a discrepancy between local and global scales in relaxor ferroelectrics, in that structural distortions occurring at the local scale are not reflected in the average global structure which remains cubic. There is an absence of direct implementation of the local symmetry in the modeling of relaxors, despite its considerable, but often unacknowledged, ability to encode local features. Central to the thesis is an explicit account for local gauge symmetry within the first-principles-derived effective Hamiltonian approach. The thesis thus aims to consider how an extended symmetry allowing independent transformations at different points in space can effectively bridge local features and macroscopical properties. An underlying question the thesis also seeks to answer is whether the disorder-induced non-trivial interplay between local and global scales can be described from a topological point of view

Multiferroics are currently intensely investigated because the coexistence and coupling of ferroic arrangements brings about new physical effects and, for the few room-temperature examples, interesting prospects for applications in various fields. This interest is illustrated by the recent publication of several articles on multiferroics in high impact reviews over the last five years. The main goal of the thesis was to look for new multiferroics by exploiting overlooked and original polar and magnetic arrangements. We more precisely investigated compounds based on lead iron tungsten PbFe2/3W1/3O3 (PFW) and lead zirconate PbZrO3 (PZO) oxides. PFW displays long- and short-range both polar and magnetic orders (ferroelectric-relaxor and antiferromagnetic-spin-glass) while PZO is antiferroelectric with antiferrodistorsivity (oxygen tilts) and existence of ferroelectric instabilities. Combining various techniques from synthesis to electric, magnetic and structural characterizations, we demonstrated that it is possible to get a multiferroic compound (50%PFW-50%PZO) with coexistence of multiple ferroic and structural arrangements with room temperature properties of practical interest. This work opens new prospects in this rich field of multiferroics in peculiar by using antiferroelectrics.

Advances in theoretical and experimental methods are making possible in depth studies of the structure and dynamics of disordered condensed systems. The very concept of order and disorder is no longer an absolute one rather as the time domain and scattering measurements suggest it depends on the distance and time scale of an observation. In this paper, we explore the extent of local order, the time scale of its persistence, and its influences on molecular dynamics in several systems in their isotropic liquid phase. The results of subpicosecond transient grating optical Kerr effect (TG-OKE)1 are presented.

Review question / Objective: The current review aims to describe the literature on the relationship between local sleep and attentional lapses in neurotypical children or children with ADHD and how this can be applied to inform our understanding of poor attention under conditions of low arousal and increased sleep pressure. The main/primary question is, what is known from the existing literature about the relationship between local sleep and attentional lapses in children? In answering this primary question, we also want to know under what conditions is local sleep occurring? For example, does local sleep occur more frequently with increased fatigue? Eligibility criteria: All papers identified must meet the following criteria for inclusion: the population is neurotypical children and children with ADHD aged between 6 and 12 years of age, published in English, full text available (where full-text is not available, authors will be contacted to request a copy of the paper). All time frames, types of sources (e.g. qualitative or quantitative research studies), geographic locations, cultural and sociodemographic contexts will be included. Review papers (i.e. systematic reviews, meta-analyses), papers with animal studies and clinical cohorts other than ADHD (e.g. autism, sleep disorders, acquired brain injuries etc.) will be excluded. As local sleep is defined as occurring during wakefulness, studies with participants who are asleep will also be excluded.

Review question / Objective: 1-How and by which means stimulated muscle from critically ill patients can liberate myokines?, 2-Which are the main characteristics of the critically ill population studied and if some of these influenced myokine´s secretion?, 5-Can myokines exert local or distant effects in critically ill patients?, 5-Which are the potential effects of myokines in critically ill patients? Eligibility criteria: Participants and context: We will include primary studies (randomized or non-randomized trials, observational studies, case series or case report) that consider hospitalized critically ill adult patients (18 years or older) in risk for developing some degree of neuromuscular disorders such as ICU-AW, diaphragmatic dysfunction, or muscle weakness, therefore the specific setting will be critical care. Concept: This review will be focused on studies regarding the secretion or measure of myokines or similar (exerkines, cytokines or interleukin) by any mean of muscle activation or muscle contraction such as physical activity, exercise or NMES, among others. The latter strategies must be understood as any mean by which muscle, and there for myocytes, are stimulated as result of muscle contraction, regardless of the frequency, intensity, time of application and muscle to be stimulated (upper limb, lower limb, thoracic or abdominal muscles). We also will consider myokine´s effects, local or systemic, over different tissues in terms of their structure or function, such as myocytes function, skeletal muscle mass and strength, degree of muscle wasting or myopathies, among others.

As of April 19, 2021, South Africa has recorded 1.56 million COVID-19 cases and almost 54,000 deaths - more than any other country on the African continent. The country has begun the national rollout of the Johnson & Johnson (J&J) COVID-19 vaccine, with over 292 thousand doses administered it aims to achieve herd immunity by vaccinating at least 67 percent of its population (around 40 million people) by the end of 2021. The government suspended its initial rollout of the AstraZeneca (AZ) vaccine due to concerns over its effectiveness, particularly against the new B.1.351 variant, which accounts for 90% of the infections in South Africa. The J&J vaccine was put on temporary hold in April due to concerns about rare clotting disorders. Although data show that expected acceptance of COVID-19 vaccines is relatively high, the suspension of two vaccines in South Africa, where fear of infection is decreasing, will likely influence public reactions. Understanding how individuals and population groups perceive and make sense of COVID-19 vaccines is critical to inform the design and implementation of risk communication and community engagement (RCCE) strategies, and guide interventions aiming to promote and sustain acceptance of COVID-19 vaccines, while encouraging compliance with other COVID-19 preventive measures. This review syntheses community perceptions of COVID-19 vaccines in South Africa to inform RCCE strategies and policies and provides examples of successful practice. It draws on multiple secondary data sources: scientific literature, qualitative and quantitative studies, grey literature, and mainstream and social media. The review was supported by consultation with four local expert key informants from different fields. It is part of the Social Science in Humanitarian Action Platform (SSHAP) series on social science considerations relating to COVID-19 vaccines. It was written for SSHAP by Tamara Roldan de Jong and Anthrologica on request of the UNICEF South Africa Country Office. Contributions were made from the RCCE Collective Service East and Southern Africa (ESAR) Region. The brief is the responsibility of SSHAP.