Relevant bibliographies by topics / Local ablation

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  2. Dissertations / Theses
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Academic literature on the topic 'Local ablation'

Author: Grafiati
Published: 11 March 2023

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Journal articles on the topic "Local ablation"

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Wada, Takuya, Katsutoshi Sugimoto, Kentaro Sakamaki, Hiroshi Takahashi, Tatsuya Kakegawa, Yusuke Tomita, Masakazu Abe, Yu Yoshimasu, Hirohito Takeuchi, and Takao Itoi. "Comparisons of Radiofrequency Ablation, Microwave Ablation, and Irreversible Electroporation by Using Propensity Score Analysis for Early Stage Hepatocellular Carcinoma." Cancers 15, no. 3 (January 25, 2023): 732. http://dx.doi.org/10.3390/cancers15030732.

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Background: Despite the diversity of thermal ablations, such as radiofrequency ablation (RFA) and microwave ablation (MWA), and non-thermal ablation, such as irreversible electroporation (IRE) cross-comparisons of multiple ablative modalities for hepatocellular carcinoma (HCC) treatment remain scarce. Thus, we investigated the therapeutic outcomes of different three ablation modalities in the treatment of early stage HCC. Methods: A total of 322 consecutive patients with 366 HCCs (mean tumor size ± standard deviation: 1.7 ± 0.9 cm) who underwent RFA (n = 216, 59.0%), MWA (n = 91, 28.3%), or IRE (n = 15, 4.7%) were included. Local tumor progression (LTP) rates for LTP were compared among the three modalities. Propensity score-matched analysis was used to reduce selection bias. Results: A significant difference in 2-year LTP rates between the IRE and RFA groups (IRE, 0.0% vs. RFA, 45.0%; p = 0.005) was found. There was no significant difference in 2-year LTP rates between the IRE and MWA groups (IRE, 0.0% vs. MWA, 25.0%; p = 0.103) as well as between the RFA and MWA groups (RFA, 18.2% vs. MWA, 20.6%; p = 0.586). Conclusion: IRE provides better local tumor control than RFA as a first-line therapeutic option for small perivascular HCC.
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Inoue, Tadahisa, and Masashi Yoneda. "Recent Updates on Local Ablative Therapy Combined with Chemotherapy for Extrahepatic Cholangiocarcinoma: Photodynamic Therapy and Radiofrequency Ablation." Current Oncology 30, no. 2 (February 9, 2023): 2159–68. http://dx.doi.org/10.3390/curroncol30020166.

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Although chemotherapy constitutes of the first-line standard therapy for unresectable extrahepatic cholangiocarcinoma, the treatment outcomes are unsatisfactory. In recent years, local ablative therapy, which is delivered to the cholangiocarcinoma lesion via the percutaneous or endoscopic approach, has garnered attention for the treatment of unresectable, extrahepatic cholangiocarcinoma. Local ablative therapy, such as photodynamic therapy and radiofrequency ablation, can achieve local tumor control. A synergistic effect may also be expected when local ablative therapy is combined with chemotherapy. However, it is a long way from being entrenched as an established therapeutic technique, and several unresolved problems persist, including the paucity of evidence comparing photodynamic therapy and radiofrequency ablation. Clinical application of photodynamic therapy and radiofrequency ablation requires sound comprehension and assimilation of the available evidence to truly benefit each individual patient. In this study, we reviewed the current status, issues, and future prospects of photodynamic therapy and radiofrequency ablation for extrahepatic cholangiocarcinoma, with a special focus on their combination with chemotherapy.
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Stone, Michael, and Bradford Wood. "Emerging Local Ablation Techniques." Seminars in Interventional Radiology 23, no. 1 (March 2006): 085–98. http://dx.doi.org/10.1055/s-2006-939844.

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Sparchez, Zeno, Tudor Mocan, Nadim All Hajjar, Adrian Bartos, Claudia Hagiu, Daniela Matei, Rares Craciun, Lavinia Patricia Mocan, Mihaela Sparchez, and Daniel Corneliu Leucuta. "Percutaneous ultrasound guided radiofrequency and microwave ablation in the treatment of hepatic metastases. A monocentric initial experience." Medical Ultrasonography 21, no. 3 (August 31, 2019): 217. http://dx.doi.org/10.11152/mu-1957.

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Aim: Percutaneous radiofrequency (RFA) and microwave ablation (MWA) are currently the best treatment options forpatients with liver metastases (LM) who cannot undergo a liver resection procedure. Presently, few studies have evaluated theefficacy of tumor ablation in beginner’s hands but none at all in hepatic metastasis. Our aim was to report the initial experiencewith ultrasound as a tool to guide tumor ablation in a low volume center with no experience in tumor ablation.Material and methods: We conducted a retrospective cohort study, on a series of 61 patients who had undergone percutaneous US-guided ablations for 82 LM between 2010 and 2015. Long term outcome predictors were assessed using univariate and multivariate analysis.Results: Complete ablation was achieved in 86.9% of cases (53/61). All MWA sessions (20/20) attained ablation margins >5mm, compared to 79% (49/62) for RFA sessions (p=0.031). Ablation time was significantly shorter for MWA, with a median duration of 10 minutes (range: 6-12) vs. 14 minutes (range: 10-19.5, p=0.003). There was no statistically significant difference in local tumor progression (LTP)-free survival rates between MWA and RFA (p=0.154). On univariate analysis, significant predictors for local recurrence were multiple metastases (p=0.013) and ablation margins <5 mm (p<.001), both retaining significance on multivariate analysis. Significant predictors for distant recurrence on both univariate and multivariate analysis were multiple metastases (p<0.001) and non-colorectal cancer metastases (p<0.05).Conclusion: A larger than 5 mm ablation size is critical for local tumor control. We favor the use of MWA due to its ability to achieve ablation in significantlyshorter times with less incomplete ablations.
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Kurup, A., Matthew Callstrom, and Michael Moynagh. "Thermal Ablation of Bone Metastases." Seminars in Interventional Radiology 35, no. 04 (October 2018): 299–308. http://dx.doi.org/10.1055/s-0038-1673422.

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AbstractImage-guided, minimally invasive, percutaneous thermal ablation of bone metastases has unique advantages compared with surgery or radiation therapy. Thermal ablation of osseous metastases may result in significant pain palliation, prevention of skeletal-related events, and durable local tumor control. This article will describe current thermal ablation techniques utilized to treat bone metastases, summarize contemporary evidence supporting such thermal ablation treatments, and outline an approach to percutaneous ablative treatment.
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Frandon, Julien, Philippe Akessoul, Tarek Kammoun, Djamel Dabli, Hélène de Forges, Jean-Paul Beregi, and Joël Greffier. "Microwave Ablation of Liver, Kidney and Lung Lesions: One-Month Response and Manufacturer’s Charts’ Reliability in Clinical Practice." Sensors 22, no. 11 (May 24, 2022): 3973. http://dx.doi.org/10.3390/s22113973.

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Background: Microwave ablation systems allow for performing tumoral destruction in oncology. The objective of this study was to assess the early response and reliability of the microwave ablation zone size at one month for liver, kidney and lung lesions, as compared to the manufacturer’s charts. Methods: Patients who underwent microwave ablation with the EmprintTM ablation system for liver, kidney and lung lesions between June 2016 and June 2018 were retrospectively reviewed. Local response and ablation zone size (major, L, and minor, l, axes) were evaluated on the one-month follow-up imaging. Results were compared to the manufacturers’ charts using the Bland–Altman analysis. Results: Fifty-five patients (mean age 68 ± 11 years; 95 lesions) were included. The one-month complete response was 94%. Liver ablations showed a good agreement with subtle, smaller ablation zones (L: −2 ± 5.7 mm; l: −5.2 ± 5.6 mm). Kidney ablations showed a moderate agreement with larger ablations for L (L: 8.69 ± 7.94 mm; l: 0.36 ± 4.77 mm). Lung ablations showed a moderate agreement, with smaller ablations for l (L: −5.45 ± 4.5 mm; l: −9.32 ± 4.72 mm). Conclusion: With 94% of early complete responses, the system showed reliable ablations for liver lesions, but larger ablations for kidney lesions, and smaller for lung lesions.
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Sparchez, Zeno, Tudor Mocan, Pompilia Radu, Lavinia Patricia Mocan, Mihaela Sparchez, Daniel Corneliu Leucuta, and Nadim Al Hajjar. "Prognostic Factors after Percutaneous Radiofrequency Ablation in the Treatment of Hepatocellular Carcinoma. Impact of Incomplete Ablation on Recurrence and Overall Survival Rates." Journal of Gastrointestinal and Liver Diseases 27, no. 4 (December 31, 2018): 399–407. http://dx.doi.org/10.15403/jgld.2014.1121.274.pro.

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Aims: To report on the long-term impact of tumor and non-tumor related parameters on local recurrence, distant recurrence and survival in patients with naïve or recurrent type hepatocellular carcinoma (HCC) treated by radiofrequency ablation (RFA).Methods: We performed 240 RFA sessions on 133 patients with 156 HCC nodules developed on a background of liver cirrhosis and analyzed the outcomes.Results: Contrast-enhanced ultrasound performed one month after RFA showed complete ablation in 119 out of 133 (89.65%) patients. With a median follow-up of 46 months, 3-, 5- and 7-year survival rates were 61.7%, 35.7%, and 22.6%, respectively. Previous ethanol injection and histological grade were significantly related to local tumor progression. Child-Pugh class, incomplete ablation, histological grade, previous ethanol injection, alpha-fetoprotein level before the treatment, and local recurrence were all significantly related to distant recurrence. Multivariate analysis demonstrated that age, Child-Pugh class, distant recurrence and multiple incomplete ablations were significantly related to survival.Conclusion: Radiofrequency ablation could be locally curative for HCC, resulting in a survival longer than 7 years. Previous ethanol injection and incomplete ablations were strongly associated with poor outcomes.
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Moskvicheva, L. I., D. V. Sidorov, M. V. Lozhkin, L. O. Petrov, and M. V. Zabelin. "Modern methods of ablation of malignant tumors of the liver." Research'n Practical Medicine Journal 5, no. 4 (December 22, 2018): 58–71. http://dx.doi.org/10.17709/2409-2231-2018-5-4-6.

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The purpose of this review is to demonstrate the possibility of performing various methods of thermal and non-thermal ablation in patients with primary and metastatic liver tumors on the basis of data available in the world medical literature.As conservative variants of local action in patients with non-resectable primary and secondary liver tumors and inoperable patients, various ablative techniques have been developed and used to achieve local control over the disease and increase the life expectancy of this group of patients. These include: radiofrequency ablation, microwave ablation, HIFU therapy, laser ablation, cryotherapy, chemical destruction of the tumor, irreversible electroporation, stereotactic radiation therapy.The effectiveness of these ablation methods depends on the size and localization of the tumor focus, and for thermal techniques — also on its location relative to large vessels. Ablative techniques have the maximum efficiency (in some cases, similar to surgical intervention) when exposed to early forms of primary cancer or secondary tumor formation of the liver in the presence of a solitary node with a maximum size up to 5 cm or 3 and less foci size up to 3 cm. The effectiveness of local destruction of tumor formations of the liver of larger diameter is increased by carrying out ablation by the second stage after performing chemoembolization of the hepatic artery or by combining various techniques of local action.The use of various modern methods of ablation of solid primary and secondary liver tumors in medical practice can expand the possibilities of antitumor treatment of this category of patients.
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Hui, Terrence CH, Justin Kwan, and Uei Pua. "Advanced Techniques in the Percutaneous Ablation of Liver Tumours." Diagnostics 11, no. 4 (March 24, 2021): 585. http://dx.doi.org/10.3390/diagnostics11040585.

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Percutaneous ablation is an accepted treatment modality for primary hepatocellular carcinoma (HCC) and liver metastases. The goal of curative ablation is to cause the necrosis of all tumour cells with an adequate margin, akin to surgical resection, while minimising local damage to non-target tissue. Aside from the ablative modality, the proceduralist must decide the most appropriate imaging modality for visualising the tumour and monitoring the ablation zone. The proceduralist may also employ protective measures to minimise injury to non-target organs. This review article discusses the important considerations an interventionalist needs to consider when performing the percutaneous ablation of liver tumours. It covers the different ablative modalities, image guidance, and protective techniques, with an emphasis on new and advanced ablative modalities and adjunctive techniques to optimise results and achieve satisfactory ablation margins.
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Sweeney, Jennifer, Nainesh Parikh, Ghassan El-Haddad, and Bela Kis. "Ablation of Intrahepatic Cholangiocarcinoma." Seminars in Interventional Radiology 36, no. 04 (October 2019): 298–302. http://dx.doi.org/10.1055/s-0039-1696649.

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AbstractIntrahepatic cholangiocarcinoma is the second most common primary liver cancer but represents only a small portion of all primary liver cancers. At the time of diagnosis, patients are often not surgical candidates due to tumor burden of other comorbidities. In addition, there is a very high rate of tumor recurrence after resection. Local regional therapies, specifically ablative therapies of radiofrequency ablation, microwave ablation, cryoablation, and irreversible electroporation, have proven to be beneficial with other hepatic tumors. The purpose of this review is to provide an overview and update of the medical literature demonstrating ablative therapy as a treatment option for intrahepatic cholangiocarcinoma.
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Dissertations / Theses on the topic "Local ablation"

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Ng, Kwok-chai Kelvin, and 吳國際. "Local and systemic effects of hepatic radiofrequency ablation in animal models." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B29434920.

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Robert, Laurence Bresler Laurent. "Facteurs prédictifs d'échec local du traitement des lésions hépatiques par radiofréquence à propos de 311 lésions hépatiques /." [S.l.] : [s.n.], 2008. http://www.scd.uhp-nancy.fr/docnum/SCDMED_T_2008_ROBERT_LAURENCE.pdf.

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Lam, Julien. "Pulsed Laser Ablation in Liquid : towards the comprehension of the growth processes." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10137/document.

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Lorsqu'une impulsion laser est focalisée sur une cible solide immergée dans un liquide, de la matière est vaporisée. La nucléation et la croissance ont lieu dans le liquide et des nanoparticules sont ainsi synthétisées. La méthode est très polyvalente puisqu'une grande variété de matériaux peut être générée. De plus, les nanoparticules sont directement stabilisées dans le solvant. L'ajout d'agent complexant n'est pas nécessaire mais peut tout de même permettre de mieux contrôler la taille des nanoparticules. Cependant, de nombreux processus sont mis en jeu durant la synthèse et l'objectif de ce travail doctoral est de développer la compréhension de ces éléments. Dans la mesure où l'ablation laser déploie une multitude d'´échelle de temps, il a fallu employer différentes méthodes pour élucider ces mécanismes. Pour commencer, je définirai un état de l'art de l'utilisation de l'ablation laser en milieu liquide et nos résultats concernant la synthèse d'aluminium oxyde dopé chrome. Par la suite, je présenterai la spectroscopie des plasmas et les questions sous-jacentes à la notion d'´équilibre dans un plasma moléculaire. Ensuite, je décrirai notre approche atomistique de la nucléation basée sur les techniques de chimie quantique. Enfin, je montrerai l'apport de l'utilisation des méthodes d'ombrographie pour mieux comprendre la thermodynamique du système au temps plus long. Notre étude démontre que la bulle formée suite à l'ablation laser est constituée essentiellement de molécule du solvant dont la quantité n'évolue quasiment pas au cours du temps de vie de la bulle
When a pulsed-laser is focused into a solid target immersed in water, the material is evaporated. Nucleation and growth occur in the liquid and nanoparticles are synthesized. The method can be considered as versatile because one can try to synthesize any kinds of materials. Also, the nanoparticles are directly stabilized by the solvant so there is no need of complexing agents. The nanoparticles are described as ligand-free. However, various processes can occur during the synthesis and the aim of my work is to understand these different components. Since the laser ablation in liquid displays a wide range of timescales, we used numerous methods to address this problem. First, I will present the use of plasma spectroscopy and the questions it raises towards local thermodynamic equilibrium. Then, I will describe our microscopic approach of nucleation based on quantum chemistry techniques. Finally, I will illustrate the advantages of shadowgraphic measurements to reach an hydrodynamic understanding of the system
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Trakymas, Mantas. "The research of risk factors for local progression of malignant hepatic tumours treated with radiofrequency ablation." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20090526_111331-15457.

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Local tumour progression remains the main problem after radiofrequency ablation of liver tumours and it is usually the only measure of treatment efficacy. The aim of our study was to investigate and evaluate the prognostic value of computed tomography and ultrasonography as well as the histological result of core biopsy material from ablated tumour on assessment of radiofrequency ablation effectiveness. Materials and methods: We have studied 68 malignant primary and metastatic hepatic tumours treated by radiofrequency ablation. Ablation was performed using perfusion electrodes. Evaluation of tumours before ablation and follow up was performed by means of contrast enhanced computed tomography and ultrasonography. Ablation zone was biopsied for histological examination. Results and conclusions: 58 successfully treated hepatic tumours were suitable for the final analysis. The local progression of nine (15.5 %) tumours was detected on follow up. Mean follow up time for analysed tumours was 16.3 months with a range from 1.7 to 38.7 months. It was showed, that: 1. The result of histological examination of ablation zone biopsy material taken one month after radiofrequency ablation of malignant liver tumour does not predict local tumour progression. 2. Tumour size 30 mm and larger and tumour proximity closer than 5 mm to hepatic vessels larger than 3 mm are significant risk factors for local tumour progression after radiofrequency ablation of malignant liver tumours 3. Tumour type... [to full text]
Nors vietinis naviko progresavimas yra esminė problema, atliekant piktybinių navikų kepenyse radijo dažnio abliaciją, dažniausiai tai yra vienintelis rodiklis, apibrėžiantis šio gydymo metodo veiksmingumą. Mūsų tyrimo tikslas buvo nustatyti kompiuterinės tomografijos ir ultragarso tyrimų bei histologinio stulpelinės biopsijos medžiagos, paimtos iš abliuoto naviko, histologinio tyrimo rezultato reikšmę anksti vertinant radijo dažnio abliacijos veiksmingumą. Tyrimo medžiaga ir metodai: Į tyrimą buvo įtraukti 68 pirminiai ir metastaziniai kepenyse esantys navikai. Radijo dažnio abliacija buvo atliekama naudojant perfuzijos elektrodus. Navikai prieš abliaciją ir po jos atliekant kontrolinius tyrimus buvo vertinami kompiuterinės tomografijos ir ultragarsinio tyrimo metodais. Po abliacijos praėjus vienam mėnesiui buvo atliekama abliacijos zonos punkcinė stulpelinė biopsija, audiniai tiriami histologiškai. Rezultatai ir išvados: Galutinei analizei buvo tinkami 58 sėkmingai gydyti navikai. Radiologinio stebėjimo metu buvo nustatyti devyni (15,5 %) vietinio naviko progresavimo atvejai. Vidutinis analizuotų navikų stebėjimo laikas buvo 16,3 mėnesiai (nuo 1,7 iki 38,7 mėnesių). Nustatyta, kad: 1. Biopsijos medžiagos, paimtos iš abliacijos zonos praėjus vienam mėnesiui po naviko, esančio kepenyse, radijo dažnio abliacijos, histologinio tyrimo rezultatas neleidžia prognozuoti vietinio naviko progresavimo 2. Naviko dydis 30 mm ir naviko lokalizacija arčiau kaip per 5 mm nuo didesnio nei 3... [toliau žr. visą tekstą]
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Bruttger, Julia [Verfasser]. "Local self-renewing of microglia after genetic ablation is dependent on Interleukin-1 signaling / Julia Bruttger." Mainz : Universitätsbibliothek der Johannes Gutenberg-Universität Mainz, 2016. http://d-nb.info/122568577X/34.

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Gorrini, Federico. "Nanodiamonds for biological applications: Synthesis by laser ablation and sensing of local magnetic environment by optical spectroscopy of NV centers." Doctoral thesis, Università degli studi di Trento, 2018. https://hdl.handle.net/11572/367592.

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Nanodiamonds (NDs) are the subject of intense investigation for their unique physical and chemical properties. Due to high hardness, optical transparency and biocompatibility, NDs find applications in tribology, catalysis and drug delivery. When enriched with nitrogen-vacancy (NV) centers, NDs can be used in bioimaging and biosensing. While the field is progressing rapidly, a number of problems are still open. In this dissertation I have tackled two important aspects for the development of NDs as biosensors: 1) production of NDs with controlled size and properties; 2) characterization and optimization of commercial fluorescent NDs as probes of paramagnetic species. In the first part of my thesis, I report a novel synthesis route for NDs by pulsed laser ablation (PLA) in water. PLA can directly produce diamonds on a nanoscopic scale, with potential advantages over alternative methods, like grinding of bulk crystals or detonation techniques. Specifically, I demonstrate synthesis of nanometric diamond crystals by PLA in an aqueous environment and investigate the thermodynamics of this process. Indeed, the synthesis of NDs by PLA is related to a drastic change in the thermodynamic state of the target upon laser irradiation. Fast laser-induced heating results in melting and superheating of the target, followed by a strong boiling, a process named “phase explosion†, and then by a fast cooling of the molten material in water. I provide a theoretical description of both superheated and undercooled liquids and of the mechanism of phase explosion. The investigation of the link between the metastable liquids (superheated or undercooled) and the synthesis of nanoparticles is carried out by theoretical analyses, computer simulations and comparison of our experimental data with previous literature. In the second part of the thesis I turn to commercial NDs enriched with (NV) centers. The purpose of the investigation is to explore the use of fluorescent NDs for sensing of paramagnetic species of biological interest. To this end, I explored the effects of size and surface coating on the optical properties and sensing capabilities of fluorescent NDs. Following a theoretical introduction to the basic properties of the NV centers and to the ground state spin dynamics of these color centers, I describe the set up used for the experimental characterization of the NDs. All NDs used in my experiments, characterized by different sizes and coatings, presented high fluorescence levels, the result of a relatively high concentration of NV center. In all NDs, I observed a fast loss in coherence due to interactions between the NV centers and with the external environment. The most striking and unexpected result concerns the dynamics of the spin-lattice relaxation time T1. Differently from previous reports, spin dynamics after polarization of NV centers could not be described by a single exponential decay, but showed a sharp signal increase that I attribute to charge dynamics and charge conversion between the negative and neutral forms of the NV center. Unexpectedly, I found that coupled charge and spin dynamics are strongly affected by paramagnetic interactions, yielding unprecedented sensitivity to subnanomolar concentrations of gadolinium, a strong paramagnetic contrast agent. The connection between relaxation dynamics and concentration of paramagnetic species can open new perspectives in biosensing and in bioimaging. As a demonstration of a practical application, I tested the sensitivity of NDs in the detection of deoxyhemoglobin, an endogenous paramagnetic species in blood.
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Salomir, Rares. "Local hyperthermia by MRI-guided focused ultrasound : fast MR-thermometry and on-line temperature control : feasibility studies of tumor thermal ablation." Bordeaux 1, 2001. http://www.theses.fr/2001BOR12418.

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La destruction locale de tumeurs sous contrôle IRM offre une nouvelle altérnative aux traite-ments classiques du cancer comme la chirurgie, la radio- et la chimio-thérapie. Parmi toutes les modalités d'induction d'une hyperthermie locale, seuls les ultrasons focalisés (USF) per-mettent une approche non-invasive. Le contrôle IRM de l'hyperthermie locale nécessite une cartographie de température rapide et fiable. La méthode basée sur la fréquence de résonance de protons de l'eau est préférée en raison de sa linéarité et de son indépendance par rapport à la nature du tissu. Les modifications locales dans la susceptibilité magnétique, ainsi que les mouvements du tissu, peuvent engendrer des erreurs dans les cartes de température obtenues par cette méthode. Des techniques de correction temps-réel sont donc demandées. La cartogra-phie rapide de température par IRM permet le contrôle temps-réel de la température au point focal. Le traitement de volumes grands par rapport à la zone focale peut être accompli par un déplacement du point focal le long d'une trajectoire optimisée, alors que le faisceau USF est émis en mode continu. Cette méthode conduit à une destruction uniforme et contigue du volume tumoral et réduit considérablement la durée du traitement, conformément aux résultats obtenus sur le carcinome VX2 implanté chez le lapin. La technologie des émetteurs en réseau phasé devrait améliorer les performances de cette méthode de chauffage. Les premiers essais cliniques chez l'homme concerneront probablement le traitement de tumeurs du sein.
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Luco, Aimee-Lee. "Vitamin D strongly influences skeletal metastasis development in breast cancer: comparison of systemic vitamin D deficiency versus local ablation of CYP27B1 in breast tumour cells." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121223.

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Vitamin D is very well known for its classical role in the maintenance of calcium and phosphorus homeostasis as well as in the prevention of rickets. More recent findings of its ability to inhibit cell proliferation, induce apoptosis, induce differentiation, inhibit angiogenesis, and modulate the immune system have made it a current topic of intense research, particularly in the field of cancer research. We used a murine model of breast cancer metastasis to bone to investigate the effect of vitamin D deficiency on the growth of breast cancer tumour cells within bone. We also established that these breast cancer tumour cells express the enzyme CYP27B1 (1α-hydroxylase) which is able to convert the inactive vitamin D precursor 25-hydroxyvitamin D (25(OH)D) to the active metabolite 1,25-dihydroxyvitamin D (1,25(OH)2D). We next examined the effect of the local activation of vitamin D by tumoral CYP27B1 on the growth of these tumour cells within bone. Although we did not see a significant difference in the growth of breast cancer tumour cells in the bones of vitamin D deficient mice as compared to vitamin D sufficient mice, we have demonstrated that breast cancer tumour cells that do not express CYP27B1 grow much more aggressively within bone than breast cancer tumour cells which express CYP27B1. This suggests a very important role for the local activation of vitamin D by extra-renal CYP27B1 on the growth of breast cancer tumour cells within the bone microenvironment. These findings suggest a potential use for 25(OH)D as a treatment for breast cancer metastasis to bone either alone or in combination.
La vitamine D est bien connue pour son rôle dans le maintien des concentrations de calcium et du phosphore dans la circulation ainsi que dans la prévention du rachitisme. La découverte plus récente de sa capacité d'inhiber la prolifération cellulaire, induire leur différentiation ainsi que l'apoptose cellulaire, inhiber l'angiogenèse, et moduler le système immunitaire rend son étude un sujet de recherche très intéressant surtout dans le domaine de la recherche sur le cancer. Nous avons étudié l'effet de la carence en vitamine D sur la croissance tumorale dans un modèle murin de métastases osseuses du cancer du sein. Nous avons aussi établi que ces cellules expriment l'enzyme CYP27B1 (1α-hydroxylase) et sont donc capables d'activer la vitamine D en son métabolite actif la 1,25-dihydroxyvitamine D (1,25(OH)2D) à partir du métabolite inactif, la 25-hydroxyvitamine D (25(OH)D). Nous avons ensuite examiné l'effet de l'activation locale de la vitamine D par les cellules tumorales dérivées du sein sur la croissance de ces cellules dans le microenvironnement osseux. Nous n'avons constaté aucune différence significative entre la croissance des cellules tumorales du cancer du sein dans l'os chez les souris carencées en vitamine D en comparaison aux souris non carencées en vitamine D. Cependant, nous avons démontré que les cellules tumorales du cancer du sein qui expriment le CYP27B1 croissent beaucoup moins vite dans l'os que les cellules tumorales qui n'expriment pas le CYP27B1. Ces résultats suggèrent un rôle très important de l'activation extra-rénale de la vitamine D par les cellules tumorales du cancer du sein pour inhiber la croissance de ces cellules dans l'os. En conclusion, ces travaux indiquent que le précurseur inactif 25(OH)D pourrait être utilisé seul ou en combinaison pour le traitement des métastases osseuses du cancer du sein.
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Trakymas, Mantas. "Piktybinių navikų, esančių kepenyse, vietinio progresavimo rizikos veiksnių tyrimas taikant radijo dažnio abliaciją." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20090526_111342-49775.

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Nors vietinis naviko progresavimas yra esminė problema, atliekant piktybinių navikų kepenyse radijo dažnio abliaciją, dažniausiai tai yra vienintelis rodiklis, apibrėžiantis šio gydymo metodo veiksmingumą. Mūsų tyrimo tikslas buvo nustatyti kompiuterinės tomografijos ir ultragarso tyrimų bei histologinio stulpelinės biopsijos medžiagos, paimtos iš abliuoto naviko, histologinio tyrimo rezultato reikšmę anksti vertinant radijo dažnio abliacijos veiksmingumą. Tyrimo medžiaga ir metodai: Į tyrimą buvo įtraukti 68 pirminiai ir metastaziniai kepenyse esantys navikai. Radijo dažnio abliacija buvo atliekama naudojant perfuzijos elektrodus. Navikai prieš abliaciją ir po jos atliekant kontrolinius tyrimus buvo vertinami kompiuterinės tomografijos ir ultragarsinio tyrimo metodais. Po abliacijos praėjus vienam mėnesiui buvo atliekama abliacijos zonos punkcinė stulpelinė biopsija, audiniai tiriami histologiškai. Rezultatai ir išvados: Galutinei analizei buvo tinkami 58 sėkmingai gydyti navikai. Radiologinio stebėjimo metu buvo nustatyti devyni (15,5 %) vietinio naviko progresavimo atvejai. Vidutinis analizuotų navikų stebėjimo laikas buvo 16,3 mėnesiai (nuo 1,7 iki 38,7 mėnesių). Nustatyta, kad: 1. Biopsijos medžiagos, paimtos iš abliacijos zonos praėjus vienam mėnesiui po naviko, esančio kepenyse, radijo dažnio abliacijos, histologinio tyrimo rezultatas neleidžia prognozuoti vietinio naviko progresavimo 2. Naviko dydis 30 mm ir naviko lokalizacija arčiau kaip per 5 mm nuo didesnio nei 3... [toliau žr. visą tekstą]
Local tumour progression remains the main problem after radiofrequency ablation of liver tumours and it is usually the only measure of treatment efficacy. The aim of our study was to investigate and evaluate the prognostic value of computed tomography and ultrasonography as well as the histological result of core biopsy material from ablated tumour on assessment of radiofrequency ablation effectiveness. Materials and methods: We have studied 68 malignant primary and metastatic hepatic tumours treated by radiofrequency ablation. Ablation was performed using perfusion electrodes. Evaluation of tumours before ablation and follow up was performed by means of contrast enhanced computed tomography and ultrasonography. Ablation zone was biopsied for histological examination. Results and conclusions: 58 successfully treated hepatic tumours were suitable for the final analysis. The local progression of nine (15.5 %) tumours was detected on follow up. Mean follow up time for analysed tumours was 16.3 months with a range from 1.7 to 38.7 months. It was showed, that: 1. The result of histological examination of ablation zone biopsy material taken one month after radiofrequency ablation of malignant liver tumour does not predict local tumour progression. 2. Tumour size 30 mm and larger and tumour proximity closer than 5 mm to hepatic vessels larger than 3 mm are significant risk factors for local tumour progression after radiofrequency ablation of malignant liver tumours 3. Tumour type... [to full text]
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Cabrera, Lozoya Rocío. "Planification de l’ablation radiofréquence des arythmies cardiaques en combinant modélisation et apprentissage automatique." Thesis, Nice, 2015. http://www.theses.fr/2015NICE4059/document.

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Les arythmies sont des perturbations du rythme cardiaque qui peuvent entrainer la mort subite et requièrent une meilleure compréhension pour planifier leur traitement. Dans cette thèse, nous intégrons des données structurelles et fonctionnelles à un maillage 3D tétraédrique biventriculaire. Le modèle biophysique simplifié de Mitchell-Schaeffer (MS) est utilisé pour étudier l’hétérogénéité des propriétés électrophysiologiques (EP) du tissu et leur rôle sur l’arythmogénèse. L’ablation par radiofréquence (ARF) en éliminant les activités ventriculaires anormales locales (LAVA) est un traitement potentiellement curatif pour la tachycardie ventriculaire, mais les études EP requises pour localiser les LAVA sont longues et invasives. Les LAVA se trouvent autour de cicatrices hétérogènes qui peuvent être imagées de façon non-invasive par IRM à rehaussement tardif. Nous utilisons des caractéristiques d’image dans un contexte d’apprentissage automatique avec des forêts aléatoires pour identifier des aires de tissu qui induisent des LAVA. Nous détaillons les sources d’erreur inhérentes aux données et leur intégration dans le processus d’apprentissage. Finalement, nous couplons le modèle MS avec des géométries du coeur spécifiques aux patients et nous modélisons le cathéter avec une approche par un dipôle pour générer des électrogrammes normaux et des LAVA aux endroits où ils ont été localisés en clinique. Cela améliore la prédiction de localisation du tissu induisant des LAVA obtenue par apprentissage sur l’image. Des cartes de confiance sont générées et peuvent être utilisées avant une ARF pour guider l’intervention. Les contributions de cette thèse ont conduit à des résultats et des preuves de concepts prometteurs
Cardiac arrhythmias are heart rhythm disruptions which can lead to sudden cardiac death. They require a deeper understanding for appropriate treatment planning. In this thesis, we integrate personalized structural and functional data into a 3D tetrahedral mesh of the biventricular myocardium. Next, the Mitchell-Schaeffer (MS) simplified biophysical model is used to study the spatial heterogeneity of electrophysiological (EP) tissue properties and their role in arrhythmogenesis. Radiofrequency ablation (RFA) with the elimination of local abnormal ventricular activities (LAVA) has recently arisen as a potentially curative treatment for ventricular tachycardia but the EP studies required to locate LAVA are lengthy and invasive. LAVA are commonly found within the heterogeneous scar, which can be imaged non-invasively with 3D delayed enhanced magnetic resonance imaging (DE-MRI). We evaluate the use of advanced image features in a random forest machine learning framework to identify areas of LAVA-inducing tissue. Furthermore, we detail the dataset’s inherent error sources and their formal integration in the training process. Finally, we construct MRI-based structural patient-specific heart models and couple them with the MS model. We model a recording catheter using a dipole approach and generate distinct normal and LAVA-like electrograms at locations where they have been found in clinics. This enriches our predictions of the locations of LAVA-inducing tissue obtained through image-based learning. Confidence maps can be generated and analyzed prior to RFA to guide the intervention. These contributions have led to promising results and proofs of concepts
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Books on the topic "Local ablation"

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Keisari, Yona. Tumor Ablation: Effects on Systemic and Local Anti-Tumor Immunity and on Other Tumor-Microenvironment Interactions. Springer, 2014.

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Keisari, Yona. Tumor Ablation: Effects on Systemic and Local Anti-Tumor Immunity and on Other Tumor-Microenvironment Interactions. Springer London, Limited, 2012.

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van Eerd, Maarten, Arno Lataster, and Maarten van Kleef. Cervical Facet Nerve Block and Radio Frequency Ablation: Fluoroscopy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0007.

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In the cervical spinal column local anesthetic can be injected intra-articularly or adjacent to the ramus medialis (medial branch) of the ramus dorsalis of the segmental nerve. Nerve blocks of the ramus medialis are preferred to an intra-articular block, because it is sometimes technically difficult to position a needle into the facet joint. These procedures are typically performed under fluoroscopy, but there are increasing numbers of studies that describe these procedures with the help of ultrasound. Reports regarding the effects of intra-articular (steroid) injections are limited. There are no comparative studies between intra-articular steroid injections and radiofrequency (RF) therapy. Based on literature about the efficacy of RF treatment and a long track record of safety of RF treatment, many pain practitioners abandon intra-articular injections in favor of RF treatment.
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Souzdalnitski, Dmitri, Adam Kramer, and Maged Guirguis. Sacroiliac Joint Injections: Fluoroscopy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0038.

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Sacroiliac joint (SIJ) injections are valuable tools for diagnosing the source of low back pain and selecting patients for a radiofrequency ablation procedure, which tends to provide long-term relief for low back pain associated with SIJ dysfunction. Sacroiliac joint injections are generally safe and well-tolerated procedures. The most common complication is initial pain from distension of the joint capsule with contrast and local anesthetic. Despite adequate intra-articular needle placement, extravasation of local anesthetic may diffuse to lumbosacral nerve roots and/or the sciatic nerve, causing transient numbness and/or weakness. This chapter reviews the advantages of fluoroscopically guided SIJ injections as well as the step-by-step technique and how to avoid complications.
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Vydyanathan, Amaresh, Karina Gritsenko, Samer N. Narouze, and Allan L. Brook. Cervical Intra-Articular Facet Injection: Computed Tomography. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0009.

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Intra-articular facet joint injections commonly refer to the injection of a contrast media and local anesthetic solution, with or without corticosteroids, directly into the facet joint space. The purpose of this procedure is pain relief as well as to establish an etiological diagnosis for surgical interventions such as joint denervation or radiofrequency ablation. Medial branch block, or facet nerve block, refers to injection of local anesthetic and possible corticosteroids along the medial branch nerve supplying the facet joints. Cervical intra-articular and facet nerve block injections are often part of a work-up for general or focal neck pain, headaches, or cervical muscle spasms. There is limited evidence for short- and long-term pain relief with cervical intra-articular facet joint injections. Cervical medial branch nerve blocks with local anesthetics demonstrate moderate evidence for short- and long-term pain relief with repeat interventions, and strong evidence exists for long-term pain relief following cervical radiofrequency neurotomy.
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Costandi, Shrif, Youssef Saweris, Michael Kot, and Nagy Mekhail. Thoracic Facet Nerve Block: Fluoroscopy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0015.

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The benefit of intra-articular local anaesthetic and steroid injections for the diagnosis and treatment of facet joint pain is controversial. Thoracic facet medial branch blocks are mainly used to confirm the diagnosis of thoracic facet arthropathy. Anatomic variability is blamed for failed treatments. Conventionally, thermal radiofrequency (RF) has been used to denervate thoracic facet joints. Cooled radiofrequency ablation (c-RFA) of the thoracic medial branch is emerging as a novel promising technique that provides relatively larger lesions that could compensate for the anatomic variation of these branches and improve outcomes. The most feared complication of RF procedures in the thoracic region is pneumothorax, which may manifest as shortness of breath or pain with inspiration. Using proper technique for placement of the needles under fluoroscopic guidance renders the risk of this complication almost negligible.
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McClenahan, Maureen F., and William Beckman. Pain Management Techniques. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0011.

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This chapter provides a broad review of various interventional pain management procedures with a focus on indications, anatomy, and complications. Specific techniques reviewed include transforaminal epidural steroid injection, lumbar sympathetic block, stellate ganglion block, cervical and lumbar radiofrequency ablation, gasserian ganglion block, sacroiliac joint injection, celiac plexus block, lateral femoral cutaneous nerve block, ilioinguinal block, lumbar medial branch block, obturator nerve block, ankle block, occipital nerve block, superior hypogastric plexus block, spinal cord stimulation, and intrathecal drug delivery systems. The chapter reviews contrast agents, neurolytic agents, botulinum toxin use, corticosteroids, and ziconotide pharmacology and side effects in addition to diagnosis and management of local anesthetic toxicity syndrome. It also discusses indications for neurosurgical techniques including dorsal root entry zone lesioning. In addition, information on radiation safety and the use of anticoagulants with neuraxial blocks is covered.
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Kainth, Daraspreet Singh, Karanpal Singh Dhaliwal, and David W. Polly. Sacroiliac Joint Fusion: Percutaneous and Open. Edited by Mehul J. Desai. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199350940.003.0020.

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Sacroiliac joint (SIJ) pain is the source of back pain in up to 25% of patients presenting with back pain. There is significant individual variation in the anatomy of the sacrum and the lumbosacral junction. SIJ pain is diagnosed with the history and physical examination. SIJ injection of a local anesthetic along with steroids is often used to confirm the diagnosis. Nonoperative treatment includes nonsteroidal anti-inflammatories, physical therapy, joint manipulation therapies, and SIJ injections. SIJ pain can also be successfully treated with radiofrequency ablation in some patients. Surgical treatment includes the open anterior sacroiliac joint fusion technique and minimally invasive techniques. The benefits of minimally invasive SIJ fusion versus open surgery include less blood loss, decreased surgical time, and shorter hospital stay. Further studies are needed to determine the long-term durability of the minimally invasive surgical techniques.
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Dirzu, Dan, Ovidiu Palea, and Sarah Choxi. Postoperative Abdominal Wall Pain. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0028.

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Abdominal pain accounts for almost 1.5% of office visits and nearly 5% of emergency department admissions each year in the United States. In 2% to 3% of patients with chronic abdominal pain, the pain arises from the abdominal wall. Postoperative abdominal wall pain is chronic, unremitting pain unaffected by eating or bowel function but exacerbated by postural change. A localized, tender trigger point can be identified, although pain may radiate over a diffuse area of the abdomen. Thorough history and physical examination can distinguish abdominal wall pain from visceral intra-abdominal pain. A positive Carnett’s sign favors an abdominal wall pain generator and not a visceral source. Injection with a local anesthetic and steroid at the area of pain may provide relief and can function also as a diagnostic test for abdominal wall pain. Refractory pain may be treated with chemical neurolysis, radiofrequency ablation, peripheral nerve stimulators, or neurectomy.
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Book chapters on the topic "Local ablation"

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Pittaluga, Paul, and Sylvain Chastanet. "Ambulatory Selective Varices Ablation Under Local Anaesthesia (ASVAL)." In Saphenous Vein-Sparing Strategies in Chronic Venous Disease, 253–64. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-70638-2_12.

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Gerbers, Jasper G., E. D. Dierselhuis, and P. C. Jutte. "Local Tumor Ablation Using Computer-Assisted Planning and Execution." In Computer-Assisted Musculoskeletal Surgery, 151–60. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-12943-3_12.

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Finch, J. Guy, Beverley G. Fosh, and Guy J. Maddern. "Direct Current Electrolysis for the Local Ablation of Liver Metastases." In Multi-Treatment Modalities of Liver Tumours, 269–92. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0547-1_22.

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Liu, Dingkun, Tianyu Fu, Danni Ai, Jingfan Fan, Hong Song, and Jian Yang. "Local Contractive Registration for Quantification of Tissue Shrinkage in Assessment of Microwave Ablation." In Medical Image Computing and Computer Assisted Intervention – MICCAI 2020, 126–34. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59716-0_13.

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Allgaier, H. P. "Resection or local ablation of colorectal cancer metastasis to the liver — pro and con." In Highlights in Gastrointestinal Oncology, 165–66. Dordrecht: Springer Netherlands, 2006. http://dx.doi.org/10.1007/1-4020-5223-5_16.

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Lee, Juhee, and Jihee Kim. "Emerging Technologies in Scar Management: Laser-Assisted Delivery of Therapeutic Agents." In Textbook on Scar Management, 443–49. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_50.

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AbstractTopical application of medications is difficult through intact skin due to physiological barrier of stratum corneum. Effective transdermal drug delivery system can offer distinct advantages over the topical application and oral administration of drugs. Laser systems have showed clinical benefits for patients in various types of scars for decades. In particular, the advent of fractional resurfacing advanced laser has enhanced the scar treatments dramatically. A fractional laser irradiates cells with high precision by controlling the area and degree of ablation through laser settings. In addition to local thermal destruction and stimulation, fractionated devices may also play an important role in drug delivery through the skin. Preclinical studies substantiate enhanced drug accumulation for a variety of topically applied drugs after ablative fractional laser therapy. Laser-assisted drug delivery is an evolving technology with potentially broad clinical applications. Multiple studies demonstrate that laser pretreatment of the skin can increase the permeability and depth of penetration of topically applied drug molecules. We discuss the mechanisms of laser-assisted drug delivery for scar treatment to enhance our understanding of this evolving technology and suggest optimal protocols of treatment.
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Komatsu, Yuki, and Akihiko Nogami. "Direct Monitoring of the Local Electrograms in the Left Ventricular Summit to Guide Ablation of Ventricular Arrhythmias." In Cardiac Electrophysiology, 379–81. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28533-3_92.

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8

Dempke, W., K. Alimi, and M. Gebel. "Lokal ablative Therapieverfahren." In Kompendium Internistische Onkologie, 882–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-31303-6_57.

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Mervis, Joshua S., and Tania J. Phillips. "The Role of Ablative Fractional Lasers in Wound Healing." In Local Wound Care for Dermatologists, 121–28. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28872-3_13.

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Orsi, Franco, Mario Bezzi, and Gianluigi Orgera. "Local Ablative Techniques in the Treatment of Locally Advanced Pancreatic Cancer." In Medical Radiology, 167–73. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/174_2010_47.

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Conference papers on the topic "Local ablation"

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Yamanishi, Yoko, Hiroki Kuriki, Shinya Sakuma, Kazuhisa Onda, and Fumihito Arai. "Local ablation by micro-electric knife." In 2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2012. http://dx.doi.org/10.1109/nems.2012.6196739.

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Mullenix, Nathan, Alex Povitsky, and Datta Gaitonde. "Modeling of Local Intense Ablation in Hypersonic Flight." In 15th AIAA International Space Planes and Hypersonic Systems and Technologies Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2008. http://dx.doi.org/10.2514/6.2008-2555.

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Kudryashov, Sergei I., Alexander A. Karabutov, N. B. Zorov, S. V. Kuznetsov, and Yu Y. Kuzyakov. "Local field effects in laser ablation of foam graphite." In International Conference on Coherent and Nonlinear Optics, edited by Vladimir I. Emel'yanov and Vladislav Y. Panchenko. SPIE, 1996. http://dx.doi.org/10.1117/12.242136.

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Ellis, Charles A., Rongen Zhang, Vince D. Calhoun, Darwin A. Carbajal, Mohammad S. E. Sendi, May D. Wang, and Robyn L. Miller. "A Novel Local Ablation Approach for Explaining Multimodal Classifiers." In 2021 IEEE 21st International Conference on Bioinformatics and Bioengineering (BIBE). IEEE, 2021. http://dx.doi.org/10.1109/bibe52308.2021.9635541.

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Yamanishi, Yoko, Hiroki Kuriki, Shinya Sakuma, Masaya Hagiwara, Tomohiro Kawahara, and Fumihito Arai. "Local ablation by plasma blade using on-chip micro-electrode." In 2011 International Symposium on Micro-NanoMechatronics and Human Science (MHS). IEEE, 2011. http://dx.doi.org/10.1109/mhs.2011.6102170.

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Haemmerich, D., and J. P. Saul. "Quantification of Local Convectional Cooling During Cardiac Radiofrequency Catheter Ablation." In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.259993.

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Haemmerich, D., and J. P. Saul. "Quantification of Local Convectional Cooling During Cardiac Radiofrequency Catheter Ablation." In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.4398898.

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Yamanishi, Y., H. Kuriki, S. Sakuma, K. Onda, T. Kawahara, and F. Arai. "Electric knife for cell surgery: Local ablation by micro-plasma discharge." In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2012. http://dx.doi.org/10.1109/memsys.2012.6170342.

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Mascia, Francesca, Gary Lam, David Threadgill, and Stuart H. Yuspa. "Abstract 18: Targeted epidermal ablation of EGFR causes local and systemic inflammation." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-18.

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Mermekli, A., N. Hare, R. Fairhead, D. K. C. Kuek, A. Gandhi, D. Dalili, R. Hughes, J. Papanikitas, and D. McKean. "Radiofrequency Ablation Combined with Augmentation for Local Tumor Control of Skeletal Metastases." In 28th Annual Scientific Meeting of the European Society of Musculoskeletal Radiology (ESSR), Virtual Edition, June 2021. Thieme Medical Publishers, Inc., 2021. http://dx.doi.org/10.1055/s-0041-1731526.

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Reports on the topic "Local ablation"

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Chen, Dongjie, Man Zhao, and Xiaoyong Xiang. Percutaneous local tumor ablation versus Stereotactic body radiotherapy for early-stage non-small cell lung cancer: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2021. http://dx.doi.org/10.37766/inplasy2021.6.0099.

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Tian, Hui, Peng Hao, Tong Li, and Qi Han. Comparison of Management and Prognosis of Operable Early Stage NSCLC：A Systematic Review Based On Network Meta-Analysis of Surgery,SBRT And Local Ablation. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2021. http://dx.doi.org/10.37766/inplasy2021.10.0110.

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