Journal articles on the topic 'Limites nettes'
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1
Bridet, Guillaume. "L’œuvre de Caillois comme expérience des limites : sociologie, histoire, anthropologie." Diogène 279-280, no. 3 (February 5, 2024): 22–34. http://dx.doi.org/10.3917/dio.279.0022.
Abstract:
Si l’œuvre de Caillois est d’une extraordinaire diversité, elle trouve également son unité dans une interrogation répétée des limites : non pas être ou ne pas être mais en être et / ou n’en être pas. Comment situer l’ensemble des réalités du monde - objets, êtres vivants, institutions, etc. - entre le dedans et le dehors des différents ensembles auxquels on est tenté de les rattacher ? L’auteur reprend de livre en livre les deux questions symétriques du dedans et du dehors et il se met en demeure d’établir de nettes distinctions lui permettant de définir sa propre position de sujet et, plus largement, l’avenir de l’individu, de la société et de la civilisation. Cet article s’efforcera de saisir l’entreprise de délimitation à laquelle se livre Caillois au fil de trois étapes sociologique, historique et anthropologique concernant l’être humain et ses cercles d’appartenance les plus couramment envisagés.
2
Schneider, Pierre-B. "Les mécanismes de défense en psychothérapie analytique de groupe en fonction des processus groupaux." Revue de psychothérapie psychanalytique de groupe 1, no. 1 (1985): 149–57. http://dx.doi.org/10.3406/rppg.1985.885.
Abstract:
I. Les mécanismes de défense sont dans la règle des témoins du fonctionnement mental individuel. S’ils apparaissent chez la majorité des membres d’un groupe à un moment donné, ils permettent le mieux l’interprétation de groupe tant prônée. 2. Dans la phase de perforation des interprétations individuelles des mécanismes de défense sont licites et mêmes indiquées dans certaines conditions. 3. Certains mécanismes archaïques (le clivage et le déni, par exemple) se rapprochent beaucoup des processus groupaux. Si on les considère comme des défenses, il faudra recourir à l’interprétation et si on estime qu’il s’agit d’un processus groupal, il faudra le traiter comme tel. 4. Le processus groupal n’appartient pas à la sphère de la pulsion et du conflit, mais à celle des besoins de sécurité, de plénitude, de destruction et de mort. 5. Il sert avant tout à créer le groupe et à assurer son fonctionnement au service du principe du plaisir. Il peut donc devenir sous ces deux aspects une résistance au processus psychodynamique. 6. En conséquence, il ne devrait se développer que pour maintenir l’existence du groupe et non pas comme une fin en elle-même. 7. Certains éléments du processus groupal peuvent devenir des défenses interprétables. 8. Ce mélange entre défenses et processus groupaux parle davantage pour l'existence d'un continuum que pour celle de deux catégories conceptuelles possédant des limites nettes.
3
Pallud, J., B. Devaux, F. Nataf, P. Varlet, M. Koziak, J. F. Meder, C. Daumas-Duport, and F. X. Roux. "Délimitation spatiale des gliomes de bas grade. Mise en évidence de cellules tumorales au-delà de l’image IRM T2 dans les oligodendrogliomes de grade « A » (Classification Sainte-Anne) à limites nettes." Neurochirurgie 50, no. 5 (November 2004): 574. http://dx.doi.org/10.1016/s0028-3770(04)98355-5.
4
Hu, Tianchen, Kefei Liao, Shan Ouyang, and Haitao Wang. "Resource Scheduling for Multitarget Imaging in a Distributed Netted Radar System Based on Maximum Scheduling Benefits." Sensors 22, no. 17 (August 25, 2022): 6400. http://dx.doi.org/10.3390/s22176400.
Abstract:
As a new radar system with improved performance, distributed multiple-input multiple-output (MIMO) radar provides a new idea for the development of netted radar. Aiming at the limited resource allocation problem of netted radar, this paper extends the idea of distributed MIMO radar to netted radar and proposes a resource scheduling algorithm for multitarget imaging in distributed netted radar based on the maximum scheduling benefits. Under the condition of the cognition of the target characteristics, the algorithm comprehensively considers the angle and dwell time to complete the multiradar and multitarget matching. Then it uses the principle of compressed sensing to calculate the pulse resources required for sparse imaging of each target on the corresponding radar. In this paper, the scheduling benefit of a radar system is expressed by weighting the three factors of the scheduling success rate, the hit value rate and the pulse resource consumption rate. The resource scheduling model is established according to the maximum scheduling benefits and solved using a heuristic algorithm. The simulation results show that compared with the traditional algorithm, this method improves the scheduling benefits of the radar system.
5
Hall, John A., and Gimme H. Walter. "Pollination of the Australian cycad Cycas ophiolitica (Cycadaceae): the limited role of wind pollination in a cycad with beetle pollinator mutualists, and its ecological significance." Journal of Tropical Ecology 34, no. 2 (March 2018): 121–34. http://dx.doi.org/10.1017/s0266467418000111.
Abstract:
Abstract:Cycads in the Zamiaceae are well known for their host-specific insect pollination mutualisms. Pollination of Cycas in the sister family Cycadaceae is less well-documented, with beetle pollination possibly coexisting with a limited potential for wind pollination, a hypothesis we tested for C. ophiolitica in Central Queensland, Australia. Cones were associated with three species of beetle: an undescribed weevil (Curculionidae), Hapalips sp. (Erotylidae) and Ulomoides sp. (Tenebrionidae). Pollination-vector exclusion experiments compared the pollination success (quantified as % ovules pollinated per cone) of control cones against bagged or netted cones that excluded wind or insects respectively (n = 10 for all treatments). Insects do pollinate C. ophiolitica in the absence of wind, the median (first quartile-third quartile) pollination success of control plants being 83.7% (60.8–87.2%) while bagged cones, from which wind, but not insects, were excluded, pollinated at 52.9% (19.5–74.8%). For netted cones, (excluding insects but not wind), pollination fell to 12.6% (10.9–45.9%). Airborne pollen (as quantified by capture on a series of adhesive pollen traps) decreased rapidly with distance from male cones, potentially becoming ineffective for wind pollination at ~5 m. Airborne pollen load in the vicinity of female cones, and distance of females from neighbouring males, suggests wind pollination may occur sporadically, but only at high spatial densities. Although Cycas appears to be primarily insect pollinated, this limited potential for ambophily may be significant given the history of dispersal and pollinator host shifts among these cycads.
6
Bas, Adeline, Léa Dieckhoff, Esther Dinh, and Sandra Clermont. "La compensation écologique en Allemagne : réglementation, pratiques et planification." Prologue 62, no. 4 (December 7, 2021): 1009–58. http://dx.doi.org/10.7202/1084257ar.
Abstract:
L’Allemagne a une expérience de la compensation relativement ancienne puisque cette dernière est introduite dès 1976 dans la démarche de non-perte nette de biodiversité de la loi fédérale sur la protection de la nature (Gesetz über Naturschutz und Landschaftspflege). Malgré cela, le système allemand de la compensation est encore largement méconnu hors d’Allemagne, car peu étudié dans la littérature internationale. À partir d’entretiens et d’une revue de littérature germanophone et anglophone, les auteures présentent les spécificités du système allemand, à l’échelle fédérale et du Bade-Wurtemberg, à travers les questions suivantes : Quels sont les facteurs expliquant le cadre législatif actuel de la compensation ? Existe-t-il des décalages entre les obligations législatives et la mise en oeuvre sur le terrain ? Quelle est la contribution de la compensation écologique à l’objectif de non-perte nette de biodiversité ? Les auteures mettent ainsi en avant les atouts et les limites du système, notamment du point de vue de la planification.
7
Jeannelle, Jean-Louis. "Le procès de l'autofiction." Études Tome 419, no. 9 (September 1, 2013): 221–30. http://dx.doi.org/10.3917/etu.4193.0221.
Abstract:
En mai 2013, Christine Angot a été condamnée à dédommager l’ex-femme de son compagnon pour le préjudice moral que celle-ci a subi en voyant sa vie sentimentale et familiale exposée dans Les Petits. Faut-il voir dans ce procès un tournant, le signe que la justice entend désormais fixer une limite nette à la possibilité d’écrire « avec la vie des autres » ?
8
Gauthier, Nicolas. "L’homme et la bête : chiens et politique dans Les Mohicans de Paris." Voix Plurielles 12, no. 2 (December 12, 2015): 138–51. http://dx.doi.org/10.26522/vp.v12i2.1276.
Abstract:
Cet article étudie comment le recours à l’animalisation dans Les Mohicans de Paris d’Alexandre Dumas est l’espace d’une véritable réflexion sur les rapports entre l’humain et l’animal. Ceci apparaît de façon nette dans la fictionnalisation du chien qui induit un brouillage des limites séparant humain et animal, brouillage qui a pour fonction de permettre l’articulation des personnages canins aux enjeux fondamentaux du roman. De façon plus précise, la mise en scène du « meilleur ami de l’homme » sert à redoubler le projet politique au cœur des Mohicans de Paris.
This paper examines how, in Les Mohicans de Paris, Alexandre Dumas assigns animalistic features to some characters to question the relations between humans and animals while portraying the various dogs in the novel in a way which blurs the limits between humans and animals. These seemingly accessory canine characters are actually closely associated with the fundamental elements of the novel. More precisely, the way “man’s best friend” is put in fiction actually repeats the political project at the heart of Les Mohicans de Paris.
9
Alfermann, Ted, Andy Strickland, Christopher Middaugh, Phong Nguyen, and Erin Leone. "Comparison of Fish Catch Between an Electric Seine and Backpack Electrofishers in Shoal Habitat of the Chipola River, Florida." Journal of Fish and Wildlife Management 9, no. 1 (December 19, 2017): 36–44. http://dx.doi.org/10.3996/032017-jfwm-026.
Abstract:
Abstract We conducted a gear comparison study to determine the best fish-sampling methodology in shoal habitat to assist with the development of a long-term fish community monitoring program on the Chipola River, Florida. Shoal habitat occurs throughout the southeastern United States, is shallow (< 1 m), and contains rock substrate and outcroppings, which limits boat electrofishing to the habitat margins. We compared the relative effectiveness of an electric seine and backpack electrofishers. Twenty-five randomly selected sites (4 m wide by 5 m long) per gear type were block netted and sampled across four shoals from August 28 to October 3, 2014. Habitat variables were recorded for each site. Using backpack electrofishers, 1,155 fish representing 21 species were collected. Using the electric seine, 1,036 fish representing 22 species were collected. We found no significant differences between gear types in mean total catch per site, mean species richness per site, Shannon's diversity, Simpson's dominance, Pielou's evenness, or the rate of species accumulation. Therefore, we consider the two gear types to be equally effective for block-netted sites in large river shoals. Differences in available equipment, funding, and personnel were compared and may ultimately determine which gear type is used in future studies.
10
Kidd, Mark S., Daniele Alaimo, Stephen Callahan, Nancy Smith Texeira, Ignat Drozdov, and Irvin Mark Modlin. "A multi-transcript blood signature for detection and assessment of gut neuroendocrine tumors." Journal of Clinical Oncology 32, no. 3_suppl (January 20, 2014): 216. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.216.
Abstract:
216 Background: Gut neuroendocrine tumors (NETs or “carcinoids”) are difficult to manage since they present with advanced disease and limited treatment options are available. Imaging is relatively insensitive in identifying treatment efficacy and the current biomarker, a neurosecretory peptide, Chromogranin A (CgA), has limited value. There is a lack of specific blood biomarker tests both to detect tumors and measure treatment responsiveness. We report the utility of a 51 marker peripheral blood signature (NETest) in comparison to CgA. Methods: The signature was validated using a 2-step qPCR method for detecting NETs in two sets (n=115; n=120) and for measuring treatment responses in a third set (n=133, including complete remission: n=4, clinically stable disease: n=82 and non-responders/clinically progressive disease: n=47). Comparison with CgA (DAKO-ELISA) was undertaken. The confounding effects of PPIs, age, sex and race were also determined for the PCR test. Results: The PCR NETest detected NETs with high sensitivity (85-98%) and specificity (93-97%). It identified pancreatic and gastrointestinal NETs with similar efficacy (>85%) as well as metastatic and non-metastatic lesions. NETest score was significantly reduced (p<0.004) following surgery or RFA and significantly higher in clinically progressive disease compared to stable disease (5.8±0.3 versus 0.6±0.1, p<0.002). The performance metrics for differentiating stable and progressive disease were sensitivity: 91% and specificity: 91%. The score was robust (reproducibility: Coefficient of Variation<2%).Long-term PPI use (>1yr), did not alter the NETest values, neither did age, sex or ethnicity. The PCR score was significantly (p<0.0005) more accurate than CgA for identifying NETs and was elevated in 91% of NETs when CgA was normal. Conclusions: This study demonstrates that a multi (51)-gene NET panel is both sensitive and specific for detecting NETs and is capable of differentiating clinically stable from progressive disease. The test is robust and significantly more sensitive and specific (accurate) than CgA. The NETest thus facilitates both accurate disease detection, and disease progress thereby permitting assessment of treatment efficacy.
11
Tájek, Přemysl, Pavla Tájková, and Vladimír Melichar. "First record of Rhinolophus ferrumequinum in north-western Bohemia, Czech Republic (Chiroptera: Rhinolophidae)." Lynx new series 54, no. 1 (2024): 227–30. http://dx.doi.org/10.37520/lynx.2023.020.
Abstract:
A male greater horseshoe bat (Rhinolophus ferruequinum) was netted at the entrance to the abandoned Mauritius mine (50°23’32”N, 12°50’01”E; 1018 m a. s. l.) in the Krušné Hory Mts (Ore Mountains) on 2 September 2023. This is the first record of this species in north-western Bohemia and first record outside the hibernation period for the whole Bohemia. The site is situated beyond the northern limits of the continuous distribution range of the species. Mist netting campaigns during the swarming period have been taking place at the site regularly since 2005 (except 2006 and 2022) and Rhinolophus ferruequinum was never recorded there before.
12
Al-Toubah, Taymeyah E., Mauro Cives, Tiffany Valone, Kirsten Blue, and Jonathan R. Strosberg. "Sensitivity and specificity of the NETest: A validation study." Journal of Clinical Oncology 37, no. 4_suppl (February 1, 2019): 222. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.222.
Abstract:
222 Background: Secretory tumor markers traditionally measured in patients with NET, such as chromogranin A, are lacking in sensitivity and specificity, and consequently are of limited clinical utility. The NETest, a novel blood multigene RNA transcript assay, has been found to be highly sensitive and specific. We sought to validate the sensitivity of the NETest in a population consisting of metastatic well-differentiated NETs, and evaluate the specificity of the test in a mixed population of metastatic non-NET GI malignancies and healthy individuals. Methods: 100 individuals consented to be tested, comprising of 49 patients with metastatic well-differentiated NETs of gastroenteropancreatic and lung origin, 25 patients with other gastrointestinal cancers, and 26 healthy individuals. Samples were sent in a blinded fashion to a central laboratory (Wren Laboratories). A NETest value of 0-13% was considered within normal range. Results: Using the ULN of 13%, the sensitivity of the NETest was 98% (CI 89%-100%) with 48 true positive results and one false negative. The overall specificity (in a mixed population of healthy individuals and non-NET cancer patients) was 63% (CI 49%-75%), with 32 true negative and 19 false positive results. Among the 26 healthy individuals the specificity was 81% (CI 62%-92%); among patients with other GI cancers, specificity was 44% (CI 27%-63%). Using an alternate and updated normal range of 0-20%, sensitivity was unchanged (98%), but specificity improved to 100% among healthy patients, and 64% among patients with other cancers. Conclusions: The sensitivity of the NETest is exceptionally high in a population of metastatic well-differentiated NETs. Specificity within a healthy population of patients is exceptionally high when using a normal range of 0-20%, and moderately high when using a normal range of 0-13%. Specificity is lower when evaluating patients with other GI malignancies. Clinical trial information: NCT02948946.
13
Chauhan, Aman, Charles Kunos, Riham El Khouli, Jill Kolesar, Heidi Weiss, William Edgar Carson, Mark B. Evers, et al. "Etctn 10388: A phase I trial of triapine and lutetium Lu 177 dotatate in well-differentiated somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs)." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): TPS4660. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.tps4660.
Abstract:
TPS4660 Background: Radiolabeled somatostatin analogues provide a means of delivering targeted radiation with a high therapeutic index to NETs that express somatostatin receptors (SSTRs). Radiolabeled somatostatin analogue Lutetium Lu 177 Dotatate (Lutathera) is a beta-emitting radionuclide, recently FDA approved for use in SSTR positive gastroenteropancreatic neuroendocrine tumors (GEPNETS) in the US based on the NETTER-1 Phase III trial. Despite favorable PFS and safety profile, the drug has limited cytoreductive capability with a 17% ORR. We hypothesize that addition of an effective radiation sensitizer could help improve antitumor activity of Lutathera. Ribonucleotide reductase (RNR) is the only enzyme responsible for conversion of ribonucleoside diphosphate to deoxyribonucleotide diphosphate (dNDP), the key building blocks for DNA synthesis. Radiation is a potent inducer of DNA double-strand breaks (DSBs), and RNR is the rate-limiting enzyme in the repair of DNA in this setting. Triapine is an inhibitor of RNR. This study will test the hypothesis that radiation sensitizer triapine can be safely combined with peptide receptor radionuclide therapy and ultimately may improve antitumor activity of Lutetium Lu 177 Dotatate. Methods: This study is an investigator initiated, NCI sponsored, multicenter phase 1 trial of triapine and Lutetium Lu 177 Dotatate in well-differentiated somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumor (GEP-NETs) after the failure of at least one line of prior systemic cancer treatment. A total of 29 patients will be enrolled in the dose escalation with help of Bayesian optimal interval design (BOIN) and dose expansion cohorts. The study will be open through the NCI ETCTN (National Cancer Institute Experimental Therapeutics Clinical Trials Network) program. Patients will be treated with 177 lutetium dotatate in combination with triapine. Triapine will be administered orally (100 mg once a day starting dose) from D1-14 with each dose of PRRT [200 mCi]. Primary endpoint is to evaluate recommended phase II dose (RP2D). Secondary endpoints are to evaluate safety, pharmacokinetics, and clinical activity (ORR and PFS). We are also evaluating NETEST, a novel blood based test that evaluates levels of 51 neuroendocrine tumor gene transcripts. In addition, the study will correlate clinical outcome with baseline somatostatin receptor density, somatic tumor mutations and germline mutations. Clinical trial information: 04234568 .
14
Saint-Laurent, Diane, and Louise Filion. "Interprétation paléoécologique des dunes à la limite des arbres, secteur nord-est de la mer d’Hudson, Québec." Géographie physique et Quaternaire 46, no. 2 (November 28, 2007): 209–20. http://dx.doi.org/10.7202/032905ar.
Abstract:
RÉSUMÉ Dans le secteur nord-est de la mer d'Hudson, soit à la limite de la toundra forestière et de la toundra, les datations au radiocarbone les plus anciennes obtenues dans les paléosols dunaires (3490 ans BP dans le secteur continental et 2660 ans BP dans le secteur côtier) font ressortir un délai de plusieurs millénaires entre la mise en place des dépôts et leur remaniement par le vent. Une comparaison avec les données de Desponts (1990) et de Filion (1984) pour la forêt boréale montre que ce décalage est beaucoup plus considérable à la limite des forêts que dans le Haut-Boréal. Elle fait aussi ressortir une diminution, du sud vers le nord, du nombre de paléosols dans les séquences sédimentaires de dunes. Les chronologies éoliennes établies en toundra forestière indiquent une nette recrudescence après 2000 ans BP. Dans la toundra, cette augmentation ressort moins nettement de la chronologie, laquelle repose sur une majorité d'horizons organiques non carbonisés. La faible proportion d'horizons carbonisés dans les paléosols dunaires de la toundra indique que les feux ne constituent pas une condition nécessaire à la formation des dunes, alors qu'en toundra forestière, les séries continues d'horizons avec charbons de bois témoignent de l'importance du rôle des feux dans les récurrences éoliennes. L'analyse macrofossile des paléosols dunaires n'a pas permis d'identifier de périodes d'expansion de la limite des arbres.
15
Clement, Dominique, Shaunak Navalkissoor, Rajaventhan Srirajaskanthan, Frédéric Courbon, Lawrence Dierickx, Amy Eccles, Valerie Lewington, et al. "Efficacy and safety of 177Lu-DOTATATE in patients (pts) with advanced pancreatic neuroendocrine tumors (pNETs): Data from the NETTER-R international, retrospective registry." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): 4116. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.4116.
Abstract:
4116 Background: Peptide receptor radionuclide therapy with 177Lu-DOTATATE is indicated in somatostatin receptor (SSTR)-positive gastroenteropancreatic neuroendocrine tumours. The NETTER-R registry builds upon the existing evidence for pts with advanced pNETs, who have limited therapeutic options. Methods: NETTER-R is a retrospective registry of pts with unresectable or metastatic, well-differentiated, SSTR-positive, progressive pNETs treated with 177Lu-DOTATATE in the UK, France and Spain. Pts who received ≥1 administration of 177Lu-DOTATATE were included. The primary endpoint was progression-free survival (PFS) based on RECIST v1.1. Secondary endpoints included overall survival (OS), safety and tumour response. Results: A total of 110 pts with pNETs were identified. Median age was 58.0 years (range 28–89) and 52.7% were male. At baseline, 96.4% of pts had progressive disease. The Ki-67 index was ≤2% in 23.6%, 3–20% in 66.4% and >20% in 2.7% of pts (7.3% missing). Metastases were present in the liver in 95.5% and bone in 29.1% of pts. Nearly all pts (90.9%) had received at least one prior anticancer therapy (somatostatin analogues: 70.0%, chemotherapy: 61.8%, protein kinase inhibitors: 38.2%). The majority of pts (70.0%) received all four scheduled cycles of 177Lu-DOTATATE. The cumulative activity was 26.6–32.6 GBq in 65.5% of pts (<26.6 GBq: 31.8%, ≥32.6 GBq: 2.7%). 12 pts were re-treated after disease progression and received 1–4 additional cycles of 177Lu-DOTATATE. By RECIST v1.1, evaluable in 62 pts, median PFS was 24.8 months (95% CI 17.5–34.5) and objective response rate was 40.3% (95% CI 28.1–53.6); all responses were partial. The response rate, including radiological, clinical, metabolic and biomarker assessments, evaluable in 100 pts, was 54.0% (95% CI 43.7–64.0), including 2 pts with complete response. Over a median follow-up of 24.5 months (range 2.0–123.4), median OS in 110 pts was 41.4 months (95% CI 28.6–50.2). 71.8% (n=79/110) of pts had at least one treatment-emergent adverse event (TEAE). The most frequent were nausea (28.2%) and fatigue (22.7%), predominantly grade 1/2 in severity. No TEAEs led to treatment discontinuation. Grade 3 anaemia and lymphopenia occurred in 1 (0.9%) and 4 (3.6%) pts, respectively. No grade ≥3 thrombocytopenia or neutropenia were reported. Renal TEAEs occurred in 6 pts (5.5%; grade 1: n=1, grade 2: n=2, grade 3: n=3). Grade 3 renal events were transient (≤24 days) and did not lead to treatment modification. No acute leukaemia or myelodysplastic syndrome were reported within the follow-up. Conclusions: In a real-world population of pts with advanced pNETs, 177Lu-DOTATATE was well tolerated with a safety profile consistent with the NETTER-1 trial. With limited follow-up, the OS and PFS compared favourably with cohorts of progressive pNET patients treated with other systemic agents.
16
BECKER, KARIN, BERNADETTE GROSSE-VELDMANN, and MAXIMILIAN WEIGEND. "Weeding the nettles VI: Taxonomic and phylogenetic studies of the Southeast Asian Urtica fissa-clade (Urticaceae)." Phytotaxa 323, no. 3 (October 3, 2017): 217. http://dx.doi.org/10.11646/phytotaxa.323.3.2.
Abstract:
Urtica L. (Urticaceae) is a subcosmopolitan genus common throughout temperate Asia. Species delimitation is very difficult and the present study investigates a group of taxa associated with Urtica fissa from East-Southeast Asia and based mainly on herbarium collections, including most of the type specimens and cultivated plants. Species limits especially of U. mairei, U. fissa and U. himalayensis have been consistently confused in both herbaria and floristic treatments. As part of a taxonomic revision we produced a molecular phylogeny of the group based on ITS1-5.8S-ITS2, psbA–trnH, trnL–trnF and trnS–trnG markers. Our revision recovers a total of five species and two subspecies: U. fissa E.Pritz. ex Diels, U. grandidentata Miq. subsp. grandidentata, U. grandidentata Miq. subsp. lombok K.Becker & Weigend, U. himalayensis Kunth & C.D.Boché, U. mairei Lév. and U. parviflora Roxb. We provide type information, diagnostic characters, a key to species identification, species conservation assessments and a list of exsiccatae for each taxon.
17
NOBLET, J. "Les systèmes d’appréciation de la valeur énergétique des aliments pour le porc." INRAE Productions Animales 6, no. 2 (February 28, 1993): 105–15. http://dx.doi.org/10.20870/productions-animales.1993.6.2.4192.
Abstract:
Pour un même aliment, il peut être attribué différentes valeurs énergétiques selon l’étape de l’utilisation de l’énergie qui est considérée (énergie digestible : ED, énergie métabolisable : EM ou énergie nette : EN) et selon le mode de prédiction au niveau de chaque étape. Dans la première partie de cet article, les effets de la composition de l’aliment et de facteurs liés à l’animal (âge, poids vif, ...) sur l’utilisation digestive et métabolique de l’énergie sont analysés de façon à présenter, dans une deuxième partie, les différents systèmes d’appréciation de la valeur énergétique des aliments pour le porc. Dans la dernière partie, les avantages, les limites et la mise en pratique des systèmes énergétiques sont analysés de manière comparative. Il en ressort que la hiérarchie entre régimes et surtout entre matières premières et, par conséquent, les résultats de la formulation sont fortement dépendants du système énergétique adopté.
18
Tanyitiku, Mary Nkongho, and Igor Casimir Njombissie Petcheu. "Effect of Stinging Nettle Leaf Flour Substitution on the Quality Characteristics of Fermented Corn Complementary Foods." Journal of Food Research 12, no. 4 (September 27, 2023): 31. http://dx.doi.org/10.5539/jfr.v12n4p31.
Abstract:
Proper complementary feeding is required to provide essential nutrients to growing infants. However, most families in developing countries are severely food insecure, leading to constant child malnutrition. This study developed fermented corn complementary foods (pap) supplemented with abundantly available and affordable stinging nettles. Stinging nettle leaf flour was incorporated into pap at 5%, 10%, 15% and 20% and evaluated in relation to nutritional, functional, and sensory properties. Soybeans were used to compare the nutritional and health benefits of nettles in infant nutrition. A gradual incorporation of nettle leaf flour increased (p<0.05) the ash, protein, and dietary fibre content of pap from 0.72%, 3.48% and 2.87% to 9.46%, 18.98% and 4.56% respectively. Likewise, nettle-enriched pap contained higher carotenoids (4.99mg/100g), vitamin C (48.76mg/100g), calcium (176.49mg/100g), phosphorus (35.21mg/100g), potassium (210.54mg/100g), and iron (284.55mg/100g) than soybean-enriched pap: 0.96, 4.40, 50.99, 29.29, 204.78 and 64.02mg/100g respectively. While total phenolic content and antioxidant activity index increased (p<0.05) with increasing addition of nettle leaf flour from 1.23mgGAE/g and 0.15 to 125.45mgGAE/g and 2.01 respectively, the metabolic glycaemic response decreased (p<0.05) from 68.53% to 35.60%. In addition, all functional qualities were within acceptable limits for complementary feeding. Nursing mothers rated the overall acceptability between 7.14 (5% nettle-enriched pap) and 6.23 (20% nettle-enriched pap), and 12 of these 20 mothers accepted to feed their babies with stinging nettle leaf flour. Our findings indicated that stinging nettle leaves are nutritionally important for improving low-cost complementary feeding and thus could contribute to the combat of infant malnutrition in rural communities.
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Pugnière-Saavedra, Frédéric. "Le détournement de nature humoristique en tant que marqueur freinant ou accélérant la circulation du discours." Çédille 1 (September 1, 2010): 129. http://dx.doi.org/10.21071/ced.v1i0.10550.
Abstract:
À travers deux types de détournement phrastiques: l’un patronymique et l’autre sémantico-interdiscursif extraits du programme télévisuel Les Deschiens (Canal+), nous montrerons qu’il s’agit d’une catégorie discursive qui ne se limite pas à produire un effet perlocutoire humoristique en superposant deux réalités (dont une va dans un sens, et la seconde dans un autre) avec une intention nette de privilégier la seconde dans la situation de communication donnée. En recouvrant en creux, un large spectre d’interprétations possibles, le détournement créé un effet stylistique et contribue à accélérer la circulation du discours en créant de la connivence avec le récepteur s’il est perçu ou à freiner la circulation du discours en créant au mieux un sentiment d’indifférence, au pire de rejet, s’il n’est pas perçu.
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Ke Zhang, Ke Zhang, Decai Zou Ke Zhang, Pei Wang Decai Zou, and Wenfang Jing Pei Wang. "A New Device for Two-Way Time-Frequency Real-Time Synchronization." 網際網路技術學刊 24, no. 3 (May 2023): 817–24. http://dx.doi.org/10.53106/160792642023052403024.
Abstract:
<p>The netted wireless sensor nodes or coherent accumulation processing in multistatic radar imaging requires high accuracy time synchronization. Although GNSS timing can also be used as a time synchronization method to serve the applications above, its timing accuracy will be limited. In this context, we present the hardware implementation for Two-Way Time-Frequency Real-Time Synchronization (TWTFRTS) with an automatic adaptive jitter elimination algorithm based on Kalman and PID, which is implemented in a real-time, low-cost, portable Xilinx ZYNQ device. A short (2 km) baseline TWTFRTS experiment was done with a pair of devices composed of a master device and a slave device. The result shows a high precision of time synchronization performance with the standard deviation (1 σ) better than 1 ns.</p> <p> </p>
21
Emerich, Yaëll, and Alexis Hudon. "Les assises conceptuelles du droit de l’environnement en droit des biens : entre patrimoine collectif et relation fiduciaire." Revue générale de droit 47, no. 2 (January 24, 2018): 519–61. http://dx.doi.org/10.7202/1042931ar.
Abstract:
Le caractère absolu de la propriété est l’un des mythes fondateurs du régime civiliste du droit des biens. Cependant, l’émergence des enjeux environnementaux a rendu nécessaire l’imposition de limites à la propriété individuelle. On peut distinguer deux mouvements de limites. Le premier mouvement, fondé sur le droit privé, est caractérisé par l’interdépendance et par un conséquentialisme anthropocentrique. Il se manifeste, notamment, par le trouble de voisinage. Le second mouvement de limites, ancré dans le droit public, est marqué par une dimension biocentrique. Il est caractérisé par une diminution nette des prérogatives du propriétaire et correspond à l’entrée en scène du droit de l’environnement. Dans une perspective de droit des biens, il est difficile de conceptualiser cet empiètement du droit environnemental sur les prérogatives du propriétaire et d’en établir le fondement. Les concepts qui se situent traditionnellement à la frontière du droit des biens et de l’environnement — comme la chose commune, la fiducie publique et le patrimoine commun — enrichissent l’analyse de l’interaction entre ces branches du droit, sans toutefois parvenir à en rendre compte entièrement. Cet article propose la figure du patrimoine collectif, fondé sur un intérêt collectif dans l’environnement, afin de légitimer l’intervention du législateur en matière environnementale dans le contexte du droit des biens. L’idée de patrimoine collectif évoque, en outre, le registre fiduciaire, particulièrement riche dans le contexte de la protection environnementale.
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Le Clainche-Piel, Marie. "Chapitre 10. La part sociale des transplantations d’organes." Journal international de bioéthique et d'éthique des sciences Vol. 34, no. 2 (August 28, 2023): 143–51. http://dx.doi.org/10.3917/jibes.342.0143.
Abstract:
Qu’est-ce que l’on partage lorsque l’on donne ou reçoit un organe ? Quels sens le don revêt-il dans le parcours de deuil d’un proche ou dans celui thérapeutique d’un patient greffé ? Ces interrogations, qui atteignent peu l’arène publique, animent les personnes qui participent concrètement à la circulation des organes, que ce soit parce qu’elles en acceptent le prélèvement, en reçoivent un ou qu’elles sont en charge de l’organiser. Par cette contribution, je souhaite éclairer les réponses à ces questions, telles qu’elles émergent dans les pratiques, et par là-même exposer la part sociale de ces opérations chirurgicales. Je reviens d’abord sur la tendance nette à la promotion du don et de la greffe d’organes depuis les années 1970 ; puis sur les limites d’une approche de la transplantation par un seul prisme biomédical ; enfin sur l’horizon des possibles en matière de reconnaissances des relations qui peuvent unir donneurs et receveurs.
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Frilling, Andreja, Daniel Kaemmerer, Mark S. Kidd, Ashley K. Clift, Justin Stebbing, Richard P. Baum, Leandro Castellano, Harpreet Singh Wasan, and Irvin Mark Modlin. "Surgery in combination with peptide receptor radionuclide therapy is effective in metastatic neuroendocrine tumors and is definable by blood gene transcript analysis." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): e15697-e15697. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e15697.
Abstract:
e15697 Background: Neuroendocrine tumours (NET) of the pancreas (PNET) or small bowel (SBNET) frequently present with metastases at initial diagnosis, undermining the efficacy of surgical treatment. Peptide receptor radionuclide therapy (PRRT) with radiolabelled somatostatin analogues, 90Y-DOTATOC and 177Lu-DOTATATE, has been shown to achieve prolonged progression-free survival (PFS) in a substantial number of non-surgical patients with advanced NET. Our aim was to prospectively determine the efficacy of a combination of radical loco-regional surgery and PRRT in patients with metastasised NET. Methods: A set of inclusion criteria was defined (e.g. G1/G2 NET, initial tumour diagnosis, treatment naïve patient, stage IV NET, positivity on 68Ga DOTA- PET/CT, eligibility for surgery and PRRT). Patients underwent PRRT within 3 months following surgery. Follow-up included biochemistry and imaging. In a sub-cohort, blood-based neuroendocrine gene transcript analysis of 51 genes (NETest) was used to define the effectiveness of treatment. Outcome measures included 5-year overall survival (OS) and PFS from initial diagnosis. Results: Twenty-five patients (5 PNET, 20 SBNET) met eligibility criteria and were included. There were 13 men (52%) and mean age was 57.1 years. All patients with SB NET underwent right hemicolectomy, terminal ileal resection and mesenteric lympadenectomy. In all PNET patients only limited pancreatic resection was required. The median number of PRRT cycles was 4 (range 2-6). Post-treatment mortality was 0%. Surgical morbidity was 12% (all Clavien-Dindo grade 1). Transient grade 1 toxicity occurred post-PRRT in 40%. NETest scores were increased in 8 patients (100%) pre-operatively and decreased in all following treatment. NETest decreases correlated with diminished tumour volume (R2=0.37, p=0.02). Median follow-up was 48 months (range 12-72months). Five-year OS was 90% and 5-year PFS was 84.3%. Conclusions: Radical loco-regional surgery for primary tumours combined with PRRT provides a novel, highly efficacious approach in metastasised NET. The NETest accurately measures the effectiveness of treatment.
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BECKER, KARIN, BERNADETTE GROSSE-VELDMANN, and MAXIMILIAN WEIGEND. "Weeding the nettles V: Taxonomic and phylogenetic studies of the eastern Asian species Urtica thunbergiana Sieb. & Zucc. (Urticaceae)." Phytotaxa 323, no. 3 (October 3, 2017): 201. http://dx.doi.org/10.11646/phytotaxa.323.3.1.
Abstract:
Urtica L. (Urticaceae) is a subcosmopolitan genus, which is also common throughout Asia. Taxon differentiation in the Asian Urtica species is difficult due to the limited diversity of taxonomically useful characters combined with a range of phenotypic variation. The present study investigates the species Urtica thunbergiana Sieb. & Zucc. (incl. U. laetevirens) from eastern Asia based on herbarium collections, including most of the type specimens. The delimitation of U. thunbergiana is expanded to include all three currently recognized subspecies of U. laetevirens Maxim. Also, one newly infraspecific taxon is described from Taiwan. Based on our revision, the recognition of a total of four subspecies of Urtica thunbergiana is proposed: subsp. thunbergiana, subsp. dentata (Hand.-Mazz.) K.Becker & Weigend, subsp. silvatica (Hand.-Mazz.) K.Becker & Weigend, and subsp. perserrata, subspec. nov. The systematic re-arrangements are based on morphological analyses and a highly resolved phylogeny based on the molecular markers ITS1–5.8S–ITS2, psbA–trnH, trnL–trnF and trnS–trnG.
25
Krogh, M. "Spatial, seasonal and biological analysis of sharks caught in the New South Wales protective beach meshing programme." Marine and Freshwater Research 45, no. 7 (1994): 1087. http://dx.doi.org/10.1071/mf9941087.
Abstract:
Data for the catches of sharks at each beach meshed in New South Wales are presented for the period from October 1972 to December 1990. High catch rates of sharks were observed at a number of these beaches. Comparison of the catches of sharks at each beach by means of hierarchical clustering and nonmetric multidimensional scaling revealed regional associations as well as some unusual relationships. Beaches at either end of each netted region (i.e. Newcastle, Sydney or Wollongong) tended to have higher catches than did beaches in the centre of each region. Hammerhead sharks (Sphyrna spp.) had significantly higher catch rates on long open beaches. Significantly higher catches of whaler (Carcharhinus spp.), white (Carcharodon carcharias), and tiger (Galeocerdo cuvier) sharks occurred when deeper water was closer to the beach. Limited biological and seasonal data are also presented for the 11 species or species groups: Sphyrna spp., Carcharhinus spp., Squatina austmlis, Heterodontus spp., Carcharodon carcharias, Galeocerdo cuvier, Carcharias taurus, Notorynchus cepedianus, Alopias spp., Isurus oxyrinchus and Orectolobus spp.
26
Anissa, Mutiara, Hadid Pratama Maska, Tangguh Ariwibawa, and Dessy Abdullah. "THE RELATIONSHIP OF GADGET ADDICTION ON MENTAL HEALTH IN MEDICAL STUDENTS." MSJ : Majority Science Journal 2, no. 1 (February 12, 2024): 178–99. http://dx.doi.org/10.61942/msj.v2i1.90.
Abstract:
Smartphone, is a term to distinguish advanced feature phones from basic feature phones. Excessive smartphone use or addiction can lead to negative health consequences such as neck pain, accidents, anxiety, depression, and sleep disorders. This study aims to determine how the influence of gadget use addiction on mental health in medical students. Method used (narrative review/systematic review with PRISMA 2020). Research was collected through searches on Google Scholar from 2019 to 2023, Ebscho from 2019 to 2023 with full text limits and PubMed from 2019 to 2023. The keyword searches used are smartphone addiction, mental health, and medical student. 210 results were found from Google Scholar, 15 results were found on Ebscho, 31 results were found on PubMed, and 21 studies were included in the study. Results of the 256 journals netted, there are 21 journals that match the category of literature review titles. There is a significant relationship between gadget addiction to mental health in medical students, especially in women.
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Strosberg, Jonathan R., Edward M. Wolin, Beth Chasen, Matthew H. Kulke, David L. Bushnell, Martyn E. Caplin, Richard P. Baum, et al. "NETTER-1 phase III: Progression-free survival, radiographic response, and preliminary overall survival results in patients with midgut neuroendocrine tumors treated with 177-Lu-Dotatate." Journal of Clinical Oncology 34, no. 4_suppl (February 1, 2016): 194. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.194.
Abstract:
194 Background: Currently, there are limited therapeutic options for patients with advanced midgut neuroendocrine tumors progressing on first-line somatostatin analog therapy. Methods: NETTER-1 is the first Phase III multicentric, randomized, controlled trial evaluating 177Lu-DOTA0-Tyr3-Octreotate (Lutathera) in patients with inoperable, progressive, somatostatin receptor positive midgut NETs. 230 patients with Grade 1-2 metastatic midgut NETs were randomized to receive Lutathera 7.4 GBq every 8 weeks (x4 administrations) versus Octreotide LAR 60 mg every 4-weeks. The primary endpoint was PFS per RECIST 1.1 criteria, with objective tumor assessment performed by an independent reading center every 12 weeks. Secondary objectives included objective response rate, overall survival, toxicity, and health-related quality of life. Results: Enrolment was completed in February 2015, with a target of 230 patients randomized (1:1) in 36 European and 15 sites in the United States. At the time of statistical analysis, the number of centrally confirmed disease progressions or deaths was 23 in the Lutathera group and 67 in the Octreotide LAR 60 mg group. The median PFS was not reached for Lutathera and was 8.4 months with 60 mg Octreotide LAR [95% CI: 5.8-11.0 months], p < 0.0001, with a hazard ratio of 0.21 [95% CI: 0.13-0.34]. Within the current evaluable patient dataset for tumor responses (n = 201), the number of CR+PR was 19 (18.8%) in the Lutathera group and 3 (3.0%) in the Octreotide LAR 60 mg group (p < 0.0004). Although the OS data were not mature enough for a definitive analysis, the number of deaths was 13 in the Lutathera group and 22 in the Octreotide LAR 60 mg group (p < 0.019 at interim analysis) which suggests an improvement in overall survival. Conclusions: The Phase III NETTER-1 trial provides evidence for a clinically meaningful and statistically significant increase in PFS and ORR, and also suggests a survival benefit in patients with advanced midgut NETs treated with Lutathera. Clinical trial information: NCT01578239.
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Graveleau, Fabien, Frank Chanier, Francis Meilliez, Jean-Yves Reynaud, and Geoffray Musial. "Observation de la surface de transgression du tuffeau thanétien sur la craie coniacienne au niveau du flanc nord de l'anticlinal du Mélantois (Nord)." Annales de la Société géologique du Nord - (2e Série), Tome 28, no. 28 (December 1, 2021): 99–110. http://dx.doi.org/10.54563/asgn.321.
Abstract:
Le suivi régulier d’un chantier de terrassement localisé à la limite des communes de Lezennes et de Villeneuve d’Ascq, au cœur de la Métropole de Lille (59, Nord), a permis d’observer et d’analyser en détail le contact géologique entre le « tuffeau » du Thanétien et la craie du Coniacien. Cette surface de contact apparaît remarquablement nette et plane, sub-horizontale et faiblement déformée. Quelques failles normales (N100-110) et décrochantes (N-S) la fracturent avec des rejets verticaux décimétriques à métriques. Cette surface est marquée par la présence d’un impressionnant réseau de terriers fossiles de type Thalassinoides isp creusés dans la craie, à remplissage thanétien et caractéristiques de l’ichnofaciès à Glossifungites. L’interprétation de cet ichnofaciès soulève de nombreux questionnements sur leur origine que de futures études de sédimentologie et de micropaléontologie devraient permettre de lever, renseignant ainsi l’histoire géologique de la transgression paléocène dans le Nord de la France.
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Hong, Sungwon, Jeong-Soo Gim, Hyo Gyeom Kim, Phil E. Cowan, and Gea-Jae Joo. "A molecular approach to identifying the relationship between resource use and availability in Eurasian otters (Lutra lutra)." Canadian Journal of Zoology 97, no. 9 (September 2019): 797–804. http://dx.doi.org/10.1139/cjz-2018-0289.
Abstract:
In South Korea, the Eurasian otter (Lutra lutra (Linnaeus, 1758)), a semi-aquatic carnivore, is found mainly in lower order streams that tend to have a low abundance of preferred prey fish species. To investigate the relationship between resource use and availability, we used DNA barcoding to identify otter diet items in 24 otter spraints (faeces) from 16 sites along the Nakdong River basin from 4 to 6 June 2014. At these sites fish availability was assessed using scoop nets and casting nets. Fish formed the bulk of otter diet, which included also frogs, mammals, and reptiles. By DNA barcoding (success rate: 72.38%), we identified 79 prey items from 105 bone remains. The diet comprised mostly fish, but frogs, mammals, and reptiles were also identified. The fish fauna and otter diet composition differed significantly. Across the study sites, members of the Cyprinidae dominated in netted samples, but occurred less frequently in otter diet. Because most Cyprinidae are fast swimmers, otters also fed on benthic fishes and frogs, suggesting limited foraging flexibility in otters and specialization on more slowly moving prey.
30
Lagarde, Paul. "La loi applicable au contrat de distribution commerciale." Revue générale de droit 21, no. 4 (March 21, 2019): 669–85. http://dx.doi.org/10.7202/1058212ar.
Abstract:
En principe, les parties à un contrat de distribution peuvent choisir librement la loi applicable à leur contrat. Mais, à défaut de choix par les parties, la loi applicable est désignée par les systèmes de conflit de lois nationaux. Pour déterminer la loi applicable aux relations fournisseur et distributeur, l’auteur analyse et compare les règles de droit international privé de différents pays et celles de conventions internationales. Il dégage une nette tendance à l’application de la loi du pays où est situé l’établissement professionnel du distributeur. Il soulève la question de l’impact que peuvent avoir certaines lois de police sur les relations entre les parties. Quant à la loi applicable au pouvoir de représentation, il aborde l’épineux problème du mandat et de la protection des tiers qui traitent avec le distributeur, face aux limites posées par le fournisseur au pouvoir de représentation du distributeur. Sur ce point, il constate que les droits internes divergent sensiblement et il expose la règle de conflit retenue par une convention internationale. L’auteur termine en étudiant les perspectives d’harmonisation du droit matériel en matière de distribution par le biais de conventions internationales.
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Masquelier, Frédéric. "Urbanisme : le maire entre le marteau et l’enclume." Administration N° 280, no. 4 (January 18, 2024): 45–47. http://dx.doi.org/10.3917/admi.280.0045.
Abstract:
À l’heure de l’inflation législative et de la multiplication des textes de lois créant de nouvelles contraintes imposées uniformément sur le territoire, le maire se voit confronté à des injonctions contradictoires portant sur la gestion foncière de sa commune et la protection de son patrimoine. Avec le nouvel objectif fixé par la loi Climat et Résilience de réduction par deux de la consommation d’espaces naturels, agricoles et forestiers (ENAF) d’ici 2031 et l’arrêt de l’artificialisation nette des sols (ZAN) à compter de 2050, le défi s’intensifie. Dénoncé par de nombreux élus, dont le président de la Région Auvergne-Rhône-Alpes, qui annonce ne pas vouloir l’appliquer, le ZAN prive les maires d’une prérogative essentielle, celle de la maîtrise de leur développement. Dans une ville moyenne comme Saint-Raphaёl (36 000 habitants), où plus de 70 % du territoire est inconstructible, où les réserves foncières sont limitées et où la population triple l’été, il devient complexe de concilier préservation du cadre de vie, création de logements, dynamisme de l’économie et sauvegarde du patrimoine.
32
Allott, Louis, Suraiya Dubash, and Eric O. Aboagye. "[18F]FET-βAG-TOCA: The Design, Evaluation and Clinical Translation of a Fluorinated Octreotide." Cancers 12, no. 4 (April 2, 2020): 865. http://dx.doi.org/10.3390/cancers12040865.
Abstract:
The success of Lutathera™ ([177Lu]Lu-DOTA-TATE) in the NETTER-1 clinical trial as a peptide receptor radionuclide therapy (PRRT) for somatostatin receptor expressing (SSTR) neuroendocrine tumours (NET) is likely to increase the demand for patient stratification by positron emission tomography (PET). The current gold standard of gallium-68 radiolabelled somatostatin analogues (e.g., [68Ga]Ga-DOTA-TATE) works effectively, but access is constrained by the limited availability and scalability of gallium-68 radiopharmaceutical production. The aim of this review is three-fold: firstly, we discuss the peptide library design, biological evaluation and clinical translation of [18F]fluoroethyltriazole-βAG-TOCA ([18F]FET-βAG-TOCA), our fluorine-18 radiolabelled octreotide; secondly, to exemplify the potential of the 2-[18F]fluoroethylazide prosthetic group and copper-catalysed azide-alkyne cycloaddition (CuAAC) chemistry in accessing good manufacturing practice (GMP) compatible radiopharmaceuticals; thirdly, we aim to illustrate a framework for the translation of similarly radiolabelled peptides, in which in vivo pharmacokinetics drives candidate selection, supported by robust radiochemistry methodology and a route to GMP production. It is hoped that this review will continue to inspire the development and translation of fluorine-18 radiolabelled peptides into clinical studies for the benefit of patients.
33
Yousafzai, Ali Muhammad, Farhad Ullah, Fathul Bari, Sumayya Raziq, Mehreen Riaz, Khalid Khan, Umar Nishan, et al. "Bioaccumulation of Some Heavy Metals: Analysis and Comparison of Cyprinus carpio and Labeo rohita from Sardaryab, Khyber Pakhtunkhwa." BioMed Research International 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/5801432.
Abstract:
We examined and compared heavy metals bioaccumulation in Cyprinus carpio and Labeo rohita netted from Sardaryab, a tributary of River Kabul. By using atomic absorption spectrometry we assessed different organs including livers, gills, and muscles. Metals studied were chromium, iron, zinc, lead, and copper. Livers of both species showed higher concentrations of metals while muscles showed the least amount. Chromium and iron were the highly concentrated metals in the gills and livers of both species. A quantity of 0.154 ± 0.011, 0.199 ± 0.0079, and 0.024 ± 0.008 μg/g of chromium was found in the gills, livers, and muscles of Cyprinus carpio, respectively. Similarly, the gills, liver, and muscles of Labeo rohita contained 0.133 ± 0.008, 0.165 ± 0.01, and 0.019 ± 0.006 μg/g of Cr, respectively. Iron was highest in carp in the range of 0.086 ± 0.01 in gills and 0.067 ± 0.011 μg/g in muscles, comparatively. All the studied metals were found within the US recommended daily dietary allowances (RDA) limits; hence no immediate risk in their consumption for human was found. The data showed that Cyprinus carpio being omnivorous and bottom feeder stored higher concentrations of metals as compared to Labeo rohita.
34
Cleary, D. F. R. "Diversity and composition of plants, butterflies and odonates in an Imperata cylindrica grassland landscape in East Kalimantan, Indonesia." Journal of Tropical Ecology 32, no. 6 (October 4, 2016): 555–60. http://dx.doi.org/10.1017/s026646741600050x.
Abstract:
Abstract:In Indonesia and elsewhere, Imperata cylindrica grassland now covers millions of hectares of land previously covered by rain forest. In the present study, shrubs, trees and climbers were recorded in sixteen 10 × 20-m plots and herb cover (ferns, grasses and herbaceous dicots) estimated in nested 2 × 2-m subplots. Butterflies and odonates were netted along 300-m transects. All plots and transects were randomly allocated to a 450 ha, I. cylindrica-dominated landscape. A total of 43 shrub, tree and climber, 16 herb, 67 butterfly and 30 odonate species were recorded. Shrubs, trees and climbers were present throughout the study area, but basal area was very low and mainly consisted of invasive species. Imperata cylindrica covered an estimated 65% of the area with other plant species or bare soil covering the remainder. Butterfly and odonate communities mainly consisted of species with large geographic distributions, but some recorded species had more limited distributions. The latter were, however, species known to associate with perturbed forest environments. Variation in the composition of butterflies and odonates was also related to variation in habitat structure (e.g. altitude and slope) and plant composition. Plant composition in particular appeared to structure both butterfly and odonate communities.
35
Jahan, Sarwat, Salman Zahir, Manzoor Khan, Khansa Khan, Mashal Asad, and Ahmed Hassan Khan. "The Journey from Basic to Clinical Pharmacology." Journal of Islamabad Medical & Dental College 13, no. 1 (May 28, 2024): 187–95. http://dx.doi.org/10.35787/jimdc.v13i1.1061.
Abstract:
Background The subjects of basic pharmacology and clinical pharmacology originate from same concepts but have a clear demarcation yet are so inter-linked and netted together that it is very critical and technical to identify and differentiate one from the other. This write-up is basically aimed to discuss and analyze the demarcations and similarities between basic and clinical pharmacology. Methodology Total 10 pharmacologists, pharmacists and medical specialists were recruited to conduct the survey from 1st December 2022 to 15th April 2023 in Northwest School of Medicine. Information was collected via literature search online, consulting Pharmacology books, libraries and discussions with subject experts. Results The basic pharmacology focuses on the study of the effects of substances on the body following experimental data that is collected via animal studies which defines the basic parameters and helps in derivation of the main foundational principles of the subject. Clinical pharmacology although follows the same basic principles and concepts but is the study of these principles in the human subjects rather than the animal studies. These studies are subjects however the two are inter-connected in many ways and the concepts go to and fro from one t the other. Conclusion The basic pharmacology is limited to the animal studies while the clinical pharmacology shelters human clinical trials and the policies, which come with the human studies and therapeutics.
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Zulkifli, Zulkifli. "Bimbingan Agama Islam Dalam Meningkatkan Ketenangan Jiwa Warga Binaan Di Lembaga Pemasyarakatan." Jurnal Bimbingan Penyuluhan Islam 1, no. 01 (June 28, 2019): 1. http://dx.doi.org/10.32332/jbpi.v1i01.1460.
Abstract:
Humans are the most perfect creatures that God created compared to others, because humans have thoughts and feelings that other creatures do not have. God revealed Islam as a guide for humans so they would not be easily lost. Religion is a benchmark for someone to do an act, because in religion there are rules that God gives in living life. The rules are not limited to human relations with God, but the rules of relations between humans and relations with their environment. Symptoms of insecurity in one's soul are easily anxious, fearful, emotional overflowing and uncontrollable, so that he cannot be friends with himself or with other people. Someone needs a mentor in the process of self-recognition and religion. It takes a variety of processes to get to know the religion of Islam, namely with the help of a counselor who provides an understanding that can be accepted by the person so that it becomes a reference in life, then someone who has a calm soul is protected from symptoms of mental disorders. Good religious formation, theoretically will produce good results for humans. Likewise religious guidance for good female prisoners will also give birth to the character of prisoners for themselves and the community. However, the phenomena found are still some of those who were netted in the same case several times, which are clearly prohibited by religious and community norms
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Scanlon, Annette Therese, and Sophie Petit. "Capture success of Fijian bats (Pteropodidae) and their evaluation as umbrella species for conservation." Pacific Conservation Biology 21, no. 4 (2015): 315. http://dx.doi.org/10.1071/pc15019.
Abstract:
Easily captured species provide powerful opportunities to motivate research and conservation action. Conversely, rare and cryptic species with low capture probability can be difficult to study. We examined the capture success of Fiji’s Pteropodidae (Pteropus tonganus, P. samoensis, Notopteris macdonaldi, and Mirimiri acrodonta) and incorporated capture success and associated observations into an assessment of their suitability as umbrella species for conservation. We caught 252 bats from 2493 mist-net-hours in lowland rainforest near Waisali on Vanua Levu, and 38 bats from 1915 mist-net-hours in cloud forest on Taveuni. Of these captures, 67% were N. macdonaldi, 16% P. tonganus, 18% P. samoensis, and <1% M. acrodonta. All species were difficult to net in cloud forest, where we recorded a female sex bias. Capture success was affected by site, season, and net height; peak capture times varied among species and between sites. N. macdonaldi was recaptured most frequently (8.8%), revealing habitual nightly movements. It has strong potential as an umbrella species for rainforest and cave-dwelling organisms of Fiji, and was readily netted. P. tonganus is an unsuitable umbrella species, P. samoensis has potential as an umbrella species, and M. acrodonta has many attributes of a flagship species. Capture efficiency of N. macdonaldi provides opportunities for monitoring and conservation management activities in Fiji. However, variability in capture success among species means that different approaches should be explored for conserving bats effectively with limited resources.
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Moazami Goudarzi, Katayoun, Désiré M. A. Belemsaga, G. Ceriotti, D. Laloë, F. Fagbohoum, N. T. Kouagou, Issa Sidibé, et al. "Caractérisation de la race bovine Somba à l’aide de marqueurs moléculaires." Revue d’élevage et de médecine vétérinaire des pays tropicaux 54, no. 2 (February 1, 2001): 129. http://dx.doi.org/10.19182/remvt.9791.
Abstract:
Le polymorphisme de quatre catégories de marqueurs du génome — 11 systèmes de groupes sanguins, 5 locus des protéines du lait, 2 locus de protéines sanguines et 33 microsatellites, soit au total 51 locus — a été analysé dans quatre populations ou « races » bovines d’Afrique de l’Ouest : les races taurines Somba et Lagunaire, la population de zébus Peuls soudanais et la population Borgou, qui provient du métissage entre taurins et zébus, en vue de caractériser le polymorphisme de la race Somba et d’évaluer sa distance génétique avec les trois autres populations, notamment la race Lagunaire avec laquelle elle présente une forte ressemblance phénotypique. Quelles qu’aient été les catégories de marqueurs ou les méthodes utilisées, les quatre populations se sont séparées nettement les unes des autres. Au niveau des groupes sanguins, les différences les plus nettes ont été observées entre les taurins et les zébus, notamment dans les systèmes A, B et S. On a retrouvé par ailleurs chez les zébus la forte fréquence des allèles AlbS et HbB, ainsi que la prédominance bien connue de l’haplotype αs1-CnC, β-CnA2, κ-CnA qui contraste avec celle de l’haplotype αs1- CnB, β-CnA1, κ-CnB chez les taurins africains. Au niveau des microsatellites, l’analyse factorielle des correspondances a souligné le rôle discriminant de l’allèle ETH 225139, dont la fréquence a été très élevée chez la race Somba, et celui des allèles Hel 13182 et INRA 037114 qui ont paru spécifiques respectivement des zébus et de la race Lagunaire. Les fréquences de ces allèles dans la population Borgou ont été sensiblement intermédiaires entre celles des zébus et celles des taurins. Dans le cadre d’une démarche visant à établir dans quelle mesure la connaissance du génotype d’un animal aux 33 marqueurs microsatellites permettait d’identifier sa population d’origine, une proportion de 97 p. 100 d’animaux bien classés a été obtenue, les erreurs de classement s’étant limitées à des zébus incorrectement qualifiés de Borgou et vice versa.
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Nam, D., and A. Pak. "COMPARATIVE ANALYSIS OF U-NET, U-NET++, TRANSUNET AND SWIN-UNET FOR LUNG X-RAY SEGMENTATION." Herald of the Kazakh-British technical university 21, no. 2 (June 30, 2024): 42–53. http://dx.doi.org/10.55452/1998-6688-2024-21-2-42-53.
Abstract:
Medical image segmentation is a widely used task in medical image processing. It allows us to receive the location and size of the required instance. Several critical factors should be considered. First, the model should provide an accurate prediction of the mask. Second, the model should not require a lot of computational resources. Finally, the distribution between the false positive and false negative predictions should be considered. We provide the comparative analysis between four deep learning models, base U-Net and its extension U-Net++, TranUNet, and Swin-UNet for lung X-ray segmentation based on trainable parameters, DICE, IoU, Hausdorff Distance, Precision and Recall. CNN models with the smallest number of parameters show the highest DICE and IoU scores than their descendants on the limited-size dataset. Based on the experiment results provided in the article U-Nethas maximum DICE, IoU, and precision. It makes the model the most appropriate for medical image segmentation. SwinU-Net is the model with minimum Hausdorff Distance. U-Net++ has the maximum Recall.
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Spronk, Inge, Charina Kullen, Catriona Burdon, and Helen O'Connor. "Relationship between nutrition knowledge and dietary intake." British Journal of Nutrition 111, no. 10 (March 13, 2014): 1713–26. http://dx.doi.org/10.1017/s0007114514000087.
Abstract:
The present systematic review examined the relationship between nutrition knowledge and dietary intake in adults (mean age ≥ 18 years). Relevant databases were searched from the earliest record until November 2012. Search terms included: nutrition; diet or food knowledge and energy intake; feeding behaviour; diet; eating; nutrient or food intake or consumption. Included studies were original research articles that used instruments providing quantitative assessment of both nutrition knowledge and dietary intake and their statistical association. The initial search netted 1 193 393 potentially relevant articles, of which twenty-nine were eligible for inclusion. Most of them were conducted in community populations (n22) with fewer (n7) in athletic populations. Due to the heterogeneity of methods used to assess nutrition knowledge and dietary intake, a meta-analysis was not possible. The majority of the studies (65·5 %: community 63·6 %; athletic 71·4 %) reported significant, positive, but weak (r< 0·5) associations between higher nutrition knowledge and dietary intake, most often a higher intake of fruit and vegetables. However, study quality ranged widely and participant representation from lower socio-economic status was limited, with most participants being tertiary educated and female. Well-designed studies using validated methodologies are needed to clarify the relationship between nutrition knowledge and dietary intake. Diet quality scores or indices that aim to evaluate compliance to dietary guidelines may be particularly valuable for assessing the relationship between nutrition knowledge and dietary intake. Nutrition knowledge is an integral component of health literacy and as low health literacy is associated with poor health outcomes, contemporary, high-quality research is needed to inform community nutrition education and public health policy.
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Rapin, F., P. Blanc, and C. Corvi. "Influence des apports sur le stock de phosphore dans le lac Léman et sur son eutrophisation." Revue des sciences de l'eau 2, no. 4 (April 12, 2005): 721–37. http://dx.doi.org/10.7202/705051ar.
Abstract:
L'eutrophisation due au phosphore a débuté à la fin des années 50. Les concentrations en phosphore étaient de 10 µg/l avant 1960 et ont atteint 90 µg/l vers 1976-1979. Depuis 1979, on note une diminution de 31 % (62 µg/l en 1988). Les apports en phosphore particulaire par les affluents principaux suivent parfaitement l'hydraulicité, mettant ainsi en évidence leur origine principalement érosive. Par contre, les apports en phosphore dissous, qui sont plus liés à l'activité humaine, ont présenté une forte croissance au début des années 1960 et se sont maintenus à un niveau élevé jusqu'en 1975. Depuis cette époque ils sont en forte décroissance (- 56 % depuis 1975). Cette décroissance est liée à la mise en service des stations d'épuration pratiquant la déphosphatation et à la mesure d'interdiction des phosphates dans les produits de lavage textiles en Suisse (01.07.1986), qui a conduit à réduire de 40 à 45 % les quantités de phosphore rejetées dans les eaux superficielles par les réseaux d'assainissement. La transparence moyenne estivale (mai-septembre) a régulièrement diminué depuis les années 1960. Lorsque les conditions climatiques sont favorables à la croissance du phytoplancton le Léman est susceptible de se comporter comme un lac eutrophe. Malgré la nette baisse des concentrations en phosphore dans le lac, il n'a pas encore été relevé de diminution de la production algale. Ceci est en accord avec les études effectuées sur d'autres lacs qui ont montré qu'il est nécessaire d'abaisser ces concentrations en-dessous de 20 à 30 µg/l pour limiter la croissance du plancton.
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Loza, Susana. "Sampling (hetero)sexuality: diva-ness and discipline in electronic dance music." Popular Music 20, no. 3 (October 2001): 349–57. http://dx.doi.org/10.1017/s0261143001001544.
Abstract:
Cyborgs, fembots and posthumans: electronic dance music and the biopolitics of fucking machinesIn the technophilic West, netizens, infomorphs and the audio digerati triumphantly-if-precociously herald this as the dawn of disembodiment. These reality hackers dream in binary code. They yearn to manufacture human-alien hybrids, ethical androids and genetically programmed clones. They already engineer digital soul divas, aural cyborgs, Nintendo's voluptuously overdrawn robo-bimbos, and the supernaturally and surgically perfect bodies purchased at Lasers R' US. They share the meat-hating philosophies of the cyber-protagonists of Neuromancer, Snow Crash and Software. They willingly computerise their passions via text sex, MUD-based gender masquerades, naughty newsgroups, techno-fetishistic video games, virtual reality-based erotic escapades, and pornosonic digital samples. Nonetheless, it seems that for the rest of us to join these intrepid cybernauts in their Age of immaterial Information, our too-solid bodies must first be anaesthetised with utopian visions and sounds of an incorporeal future. So electronic dance music, popular culture and modern science inject the flesh with fantasies of immortality, limitless pleasures, and unadulterated agency. With their tax-funded market research and their potent techno-imaginings, entertainment systems, netters, digital dance music producers, and radically hopeful scientists prepare human matter to be dematerialised and devoured byte by agonising byte. In other words, they passionately fabricate the human-machine hybrid also known as the cyborg, the fembot and the posthuman. These techno-organic entities traverse the space between desire and dread; their indeterminate forms simultaneously destabilise and reconfigure the dualistic limits of liberal humanist subjectivity. Each incarnation plots the feared consequences and perplexing possibilities of boundary transgressions between the human and the machine quite differently.
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ERICKSON, MARILYN C., JEAN LIAO, JENNIFER L. CANNON, and YNES R. ORTEGA. "Role of Brushes and Peelers in Removal of Escherichia coli O157:H7 and Salmonella from Produce in Domestic Kitchens." Journal of Food Protection 78, no. 9 (September 1, 2015): 1624–31. http://dx.doi.org/10.4315/0362-028x.jfp-15-125.
Abstract:
Consumers are being advised to increase their consumption of fruits and vegetables to reduce their risk of chronic disease. However, to achieve that goal, consumers must be able to implement protocols in their kitchens to reduce their risk of consuming contaminated produce. To address this issue, a study was conducted to monitor the fate of Escherichia coli O157:H7 and Salmonella on produce (cantaloupe, honeydew melon, carrots, and celery) that were subjected to brushing or peeling using common kitchen utensils. Removal of similar levels of Salmonella from carrots was accomplished by peeling and by brushing, but significantly greater removal of E. coli O157:H7 from carrots was accomplished by peeling than by brushing under running water (P < 0.05). Brushing removed significantly fewer pathogens from contaminated cantaloupes than from other produce items (P < 0.05), suggesting that the netted rind provided sites where the pathogen cells could evade the brush bristles. A Sparta polyester brush was less effective than a scouring pad for removing Salmonella from carrots (P < 0.05). In all cases, brushing and peeling failed to eliminate the pathogens from the produce items, which may be the result of contamination of the utensil during use. High incidences of contamination (77 to 92%) were found among peelers used on carrots or celery, the Sparta brush used on carrots, and the scouring pad used on carrots and cantaloupe. Of the utensils investigated, the nylon brush had the lowest incidence of pathogen transference from contaminated produce (0 to 12%). Transfer of pathogens from a potentially contaminated Sparta brush or peeler to uncontaminated carrots did not occur or occurred only on the first of seven carrots processed with the utensil. Therefore, risk of cross-contamination from contaminated utensils to uncontaminated produce may be limited.
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Chauhan, Aman, Charles Kunos, Susanne M. Arnold, Heidi Weiss, S. Percy Ivy, Steven Gore, Lawrence Rubinstein, et al. "A phase II randomized control trial of triapine plus lutetium 177 DOTATATE versus lutetium 177 DOTATATE alone for well-differentiated somatostatin receptor-positive neuroendocrine tumors." Journal of Clinical Oncology 42, no. 16_suppl (June 1, 2024): TPS4202. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.tps4202.
Abstract:
TPS4202 Background: Radiolabeled somatostatin analogues provide a means of delivering targeted radiation with a high therapeutic index to NETs that express somatostatin receptors (SSTRs). Radiolabeled somatostatin analogue Lutetium 177 DOTATATE (Lutathera) is a beta-emitting radionuclide, FDA approved for use in SSTR positive gastroenteropancreatic neuroendocrine tumors (GEPNETS) in the US based on the NETTER-1 Phase III trial. Despite favorable PFS and safety profile, the drug has limited cytoreductive capability with a 14% ORR. Peptide receptor radionuclide therapy (PRRT) also doesn’t seem to be very effective in treating peritoneal disease. We hypothesize that addition of an effective radiation sensitizer could help improve antitumor activity of Lutathera. Radiation is a potent inducer of DNA double-strand breaks, and ribonucleotide reductase (RNR) is the rate-limiting enzyme in the synthesis and repair of DNA, making RNR-targeted therapy a rationale therapeutic strategy for radiosensitization. ETCTN 10388 (NCT04234568) evaluated safety and efficacy of the combination of lutetium 177 DOTATATE, a beta-emitting radionuclide in combination with triapine, a ribonucleotide reductase (RNR) inhibitor. The combination of triapine and Lu-177 DOTATATE was safe with preliminary efficacy signals. Methods: This study is an investigator initiated, NCI sponsored, multicenter randomized phase 2 trial of triapine and lutetium Lu 177 DOTATATE in well-differentiated somatostatin receptor-positive neuroendocrine tumor. A total of 94 patients will be equally randomized to either Lu-177 dotatate or Triapine + Lu-177 dotatate arm. The study will be open through the NCI ETCTN (National Cancer Institute Experimental Therapeutics Clinical Trials Network) program. Triapine will be administered orally from D1-14 with each dose of PRRT [200 mCi]. Primary endpoint is to evaluate overall response rate (ORR). Secondary endpoint is to evaluate median PFS. We are also evaluating triapine PK, plasma deoxyribonucleosides, circulating DNA and plasma hPG80, a novel blood based diagnostic biomarker. Clinical trial information: 05724108.
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Senghor, F., I. Thiam, MCN Odah, AM Gaye, and K. Ndiaye. "C50: Cancer du col utérin, un risque considérable même après 65 ans : Une expérience dakaroise." African Journal of Oncology 2, no. 1 Supplement (March 1, 2022): S22—S23. http://dx.doi.org/10.54266/ajo.2.1s.c50.trzv1670.
Abstract:
INTRODUCTION : Le cancer du col de l’utérus est un problème de santé publique et le deuxième cancer le plus fréquent chez la femme dans le monde et le premier en Afrique. Grâce aux stratégies de dépistage organisé dans les pays développés, l’incidence du cancer du col a diminué chez les femmes jeunes, mais sa fréquence chez les femmes de 70 ans et plus reste inchangée. En Afrique, cette incidence augmente avec une part des personnes âgés de plus de 65 ans sous-évalués. Nous nous sommes intéressés à étudier le profil épidémiologique et anatomopathologique des cancers du col chez les femmes africaines de plus 65 ans (limite d’âge pour le dépistage) en vue d’examiner la pertinence de la poursuite du dépistage chez ces femmes. MATERIELS ET METHODES : Etude rétrospective descriptive et analytique sur cinq ans allant de 2016 à 2020 portant sur les comptes-rendus anatomopathologiques, blocs et lames des prélèvements du col utérin, au laboratoire d’Anatomie et Cytologie Pathologiques de l’Hôpital Aristide le Dantec. Nous avons inclus tous les cas de cancer du col utérin confirmé des patientes de 65 ans et plus. RESULTATS : Nous avons colligé 203 cas de cancer du col chez la femme de plus 65 ans en cinq ans (2016 à 2021). La moyenne d’âge était de 71 ans avec des extrêmes allant de 65 à 90 ans. Les patientes étaient essentiellement de grandes multigestes et multipares. Les prélèvements étaient exclusivement des biopsies. Les cancers étaient totalement de nature épithéliale, avec une nette prédominance des carcinomes épidermoïdes (91,6%). Ces cancers représentent 91,03% des échantillons du col utérin reçus pour cette tranche d’âge et un sixième de l’ensemble des cancers du col utérin tout âge confondu. CONCLUSION : Notre étude confirme que l’incidence du cancer du col chez les femmes âgées de plus de 65 ans est considérable. Il est nécessaire de dépister les femmes après 65 ans.
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Thomas, P. "Actualités du trouble de personnalité borderline." European Psychiatry 29, S3 (November 2014): 555–56. http://dx.doi.org/10.1016/j.eurpsy.2014.09.360.
Abstract:
Le trouble de personnalité borderline (TPB), ou état limite, est le plus fréquent des troubles de la personnalité. Il touche en effet 0,5 à 6 % de la population générale, 10 % des patients suivis en ambulatoire et jusqu’à 50 % des patients hospitalisés en psychiatrie. Le TPB présente un taux de suicide pouvant atteindre 10 % [1]. Pour les professionnels de santé mentale, cette pathologie souffre d’une image parfois négative, et suscite d’importants questionnements concernant le flou qui entoure son diagnostic et son étiopathogénie, la gravité et l’instabilité des symptômes, les difficultés de prise en charge et les relations particulières que ces patients tendent à nouer avec les soignants et les institutions. Pourtant, le TPB est un trouble bien défini avec des critères précis. De plus, la recherche se développe au niveau clinique, neurobiologique et psychothérapeutique et permet de réaliser des avancées importantes dans la compréhension et la prise en charge de ce trouble [2]. Ce symposium a pour objectif de présenter différents aspects des avancées réalisées dans le TPB. Au niveau clinique, la présence hallucinations chez les patients présentant un TPB est un phénomène encore mal reconnu et peu étudié. Pourtant ces hallucinations, principalement acoustico-verbales, sont retrouvées chez environ 30 % des patients atteint de TPB, et les recherches à leur sujet révèlent des pistes intéressantes pour la pratique clinique [3]. Au niveau étiopathogénique, il existe de nombreux arguments en faveur d’une interaction gène-environnement dans la genèse du TPB. Les pistes actuelles dans ce domaine correspondent à l’étude de nouveaux gènes candidats (axe du stress), au couplage de méthodes et à l’utilisation du concept de gène de plasticité plutôt que de gènes de vulnérabilité [4]. Finalement, les traitements et le développement de techniques psychothérapeutiques spécifiques au TPB ont permis une nette amélioration dans sa prise en charge.
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O Donoghue, K., and L. Larkin. "AB1334-HPR BARRIERS AND FACILITATORS TO PHYSICAL ACTIVITY IN JUVENILE IDIOPATHIC ARTHRITIS (JIA): A SCOPING REVIEW." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1955.2–1955. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3550.
Abstract:
Background:Physical activity is an important aspect in the management of JIA (1). However physical activity levels are low in this population (2). Limited research has been conducted to identify definitive barriers and facilitators to physical activity in children and adolescents who have JIA.Objectives:The objective of this scoping review was to identify the common barriers and facilitators to physical activity in JIA.Methods:Original studies, either quantitative or qualitative, including participants with a diagnosis of JIA, who were under 18 years of age were included. Two independent reviewers carried out a search of the literature and full text reviews of papers to determine eligibility for inclusion. The Critical Skills Appraisal Programme (CASP), Appraisal tool for Cross-Sectional Studies (AXIS) and Downs and Black critical appraisal tools were used to assess the quality of the included research articles.Results:Eighteen studies were included in the review. The included studies were of a variety of low, moderate and high quality. The synthesis of the data identified pain to be the most common barrier and the modification of physical activities to the need of the individual to be the most common facilitator to physical activity in JIA.Conclusion:Identifying the most common barriers and facilitators to physical activity allows clinicians to apply better management strategies when treating an individual with JIA. Our findings demonstrate the need for further research in this area to assist increasing physical activity participation for children and adolescents who have JIA.References:[1]Kuntze, G., Nesbitt, C., Whittaker, J.L., Nettel-Aguirre, A., Toomey, C., Esau, S., Doyle-Baker, P.K., Shank, J., Brooks, J., Benseler, S., Emery, C.A. (2018) ‘Exercise Therapy in Juvenile Idiopathic Arthritis: A Systematic Review and Meta-Analysis’,Archives of Physical Medicine and Rehabilitation, 99(1), 178-193[2]Bos, G.J.F.J., Lelieveld, O.T.H.M., Armbrust, W., Sauer, P.J.J., Geertzen, J.H.B., Dijkstra, P.U. (2016) ‘Physical activity in children with Juvenile Idiopathic Arthritis compared to controls’, Pediatric Rheumatology, 14(1), 42.Disclosure of Interests:None declared
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Mukai, Y., H. Yoshikawa, and H. Kobayashi. "THE RELATIONSHIP BETWEEN THE LENGTH OF THE CUPULAE OF FREE NEUROMASTS AND FEEDING ABILITY IN LARVAE OF THE WILLOW SHINER GNATHOPOGON ELONGATUS CAERULESCENS (TELEOSTEI, CYPRINIDAE)." Journal of Experimental Biology 197, no. 1 (December 1, 1994): 399–403. http://dx.doi.org/10.1242/jeb.197.1.399.
Abstract:
Free mechanosensory neuromasts of larval fishes have been described as playing a complementary role to vision in feeding behaviour (Disler, 1971; Iwai, 1972a,b). In certain species or under limited conditions, free neuromasts play a major role in detecting prey. The larvae of mottled sculpin Cottus bairdi can feed on Artemia in the dark by using free neuromasts (Jones and Janssen, 1992). Artificially blinded surface-feeding Aplocheilus lineatus can detect insects on the water surface by means of free neuromasts (Muller and Schwarts, 1982; Tittel et al. 1984; Bleckmann, 1988; Bleckmann et al. 1989). Furthermore, vibrations produced by swimming crustaceans are known to be a potent natural stimulus for the lateral line system in the Antarctic fish Pagothenia borchgrevinki (Montgomery and Macdonald, 1987; Montgomery, 1989). We found that larvae of a plankton feeder, the willow shiner Gnathopogon elongatus caerulescens (Sauvage) (Cypriniformes, Cyprinidae), fed on nauplii of Artemia in complete darkness. Ototoxic compounds, such as streptomycin, have been shown to disturb the function of the lateral line organ or free neuromasts (Kaus, 1987; Blaxter and Fuiman, 1989; Janssen, 1990; Jones and Janssen, 1992). Willow shiner larvae treated with streptomycin sulphate no longer feed on Artemia in the dark (Y. Mukai, in preparation). The willow shiner inhabits calm lakes and feeds on zooplanktonic prey (Nakamura, 1949). The larvae show a high sensitivity to minute water displacements. From these observations and from our findings, it appears that larval willow shiner must feed on zooplankton by using free neuromasts in the dark. In larval willow shiner, the vane-like cupulae of the free neuromasts protrude from the body surface and the long cupulae are 100-250 microm in length (Mukai and Kobayashi, 1991). The prey is detected by the free neuromasts as a result of a slight bending of the cupula in response to local water movements. The shape of the cupula, especially its length, must therefore be related to the sensitivity of the free neuromast, as inferred from the results of Coombs and Janssen (1989) and van Netten and Kroese (1989).
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Yu, Rui, Xinfeng Wang, Zhaofeng Wang, Long Wang, Xiaoqiang Zhang, Wengang Liu, and Qiao Zhang. "Study on the Mechanism of Liquid Carbon Dioxide Fracturing and Permeability Enhancement Technology in Low Permeability Thick Coal Seam." Geofluids 2022 (October 14, 2022): 1–20. http://dx.doi.org/10.1155/2022/4688347.
Abstract:
For the urgent need of gas management in high gas and coal and gas herniated mines, liquid CO2 fracturing is used to increase the permeability and promote the pumping treatment of low permeability coal seams. In this paper, we construct the coal deformation and damage model, gas diffusion and seepage model, and coal seam permeability change model; simulate and solve the plastic zone and gas pressure of coal seam after fracturing with the COMSOL Multiphysics software; and set 4 different hole spacing groups of 2 m, 3 m, 4 m, and 5 m and 3 different hole layout methods of single hole, double hole, and net hole to get the best solution for liquid CO2 fracturing. At the same time, the specific effect of liquid CO2 on coal seam fracturing was verified by field experiments using coal seam No. 2 of the 12316 comprehensive mining working face of Wangjialing Coal Mine as the background of the study. The numerical simulation results show that the stress concentration area around the fracturing hole appears in single-hole fracturing, and the coal seam is prone to fatigue damage in this area, but the damage range is limited, and the reduction of gas pressure after fracturing is small; the fracturing effect of double-hole and net-hole fracturing is better than that of single-hole fracturing due to the existence of sufficient critical air surface. After negative pressure extraction, the coal seam gas pressure is positively correlated with the distance from extraction hole to fracturing hole, and the best extraction effect can be seen from the field experimental results with the netted hole layout at the hole distance of 3 m. The field test results show that the pure amount of gas extraction is improved about 4 times after liquid CO2 fracturing, which proves that liquid CO2 fracturing has a better enhancement effect on gas management in low permeability coal seams.
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Chernokova, Yevheniya S. "THE ESSENCE OF AN IMAGE IN ENGLISH-AMERICAN IMAGISM: SINGULAR VERSUS UNIVERSAL." Alfred Nobel University Journal of Philology 1, no. 25 (May 30, 2023): 8–19. http://dx.doi.org/10.32342/2523-4463-2023-1-25-1.
Abstract:
The paper is aimed at filling the gap in learning the formative image peculiarities of the English and American Imagistic poetry by analyzing the correspondence of the internal and the external and their correlation. This is where the answer lies, why T.S. Eliot called Imagism “an opening salvo” of English/ American Modernist poetry. It also explains the reason for a long-term effect of this short-term “school” in the English poetry of the twentieth century. Imagism hasn’t left any extended or profound theory as far as the criteria for producing “hard, dry images” (T.E.Hulme) are concerned. Since then the problem has been under-studied and calls for more in-depth analysis. The modern theoretical background of the paper includes the ideas of S. Averintsev and M. Gasparov, Paul Ricoeur and Gaston Bachelard; the criticism of the Imagism founders (T.E. Hulme and E. Pound) as well as its present-day English and American researchers. The major theoretical points highlight the important features of image transformation in Imagism: the dual (semantic and psychological) nature of an image (P. Ricoeur); loss of its axiological constituent thus forfeiting its wholeness (M. Girshman); its non-permanent essence (G. Bachelard). All these “new” sides underlie too general and vague definition of an image as “an intellectual and emotional complex in an instant of time” given by Ezra Pound, his definitive denial of using images as “ornaments” and the emphasis on the image affiliation with speech, not language. The fight doesn’t have to be limited only to opposing Romanticism (as in Hulme’s “Romanticism and Classicism”). Equally significant and far more sophisticated is the distinction between Symbolic and Imagistic essence of an image (Pound’s “Retrospect” and “Gaudier Brzeska”). For Pound, the main criterion is the receptive potential of an image, its semantic openness which offsets its meaning as finally fixed in some symbol. The paper examines the possibility to apply Roland Barthes’s idea (“L`imagination du signe”, 1962) of the crucial influence of the interior (symbolic) relationship and two exterior (paradigmatic and syntagmatic) relationships on the formation of both single image and the total imagery of a certain type of art conscience – consequently, of Symbolism, Romanticism and Imagism. In the early period of Imagism development (the poetry of F. Flint, E. Storer, to a lesser extent, of T.E. Hulme) the images still preserve the inner affinity with the signified objects (concepts) as seen in Romantic and Symbolic image “patterns”. And throughout Imagism development, this inner affinity is being weakened until a distant outer resemblance is left. It is clearly seen in Hulme’s “Autumn”, Pound’s “In a Station of the Metro”, H.D.’s “Oread”, “Hermes of the Ways” et al. The close reading of the W.C. Williams’s poem “The Red Wheelbarrow” is carried out in front of the “Tall Nettles” by Edward Thomas (1878–1917), his contemporary, who is now considered to be one of the “non-Modernist modern” poets. It is stated that the central image of the red wheelbarrow in its every detail constitutes a modern pastoral while Thomas’s nettles stand for psychological matrix of personal melancholy and despair. Syntagmatic relations also involve the further interaction of signs in the form of “superposition”, forming montage as one of the important Мodernist techniques not only in poetry, but also in Мodernist prose. And it becomes evident that it is not a mechanically borrowed cinema technique, as it is commonly viewed, but a deeper, “syntagmatic” similarity. The result of the research, based on the analysis undertaken, seems to prove its initial point: the poems of T.E. Hulme, Ezra Pound, W. Carlos Williams, Hilda Doolittle (H.D.) taken as models, manifest that the image in Imagism is every time constructed as a new actual syntagma of the common imagination of a poet and a reader to become the unique image for every single poem without its further “universal” use in any virtual paradigm.