Journal articles: 'Limite KPg'

1

KULA, Semiha, and Esra BUKOVA GÜZEL. "Reflections of Mathematics Student Teachers’ Knowledge Related to the Purposes of the Curriculum on Their Limit Teaching." Kuramsal Eğitimbilim 8, no. 1 (March 9, 2015): 28–49. http://dx.doi.org/10.5578/keg.8758.

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MILLER, Richard W., Robert R. EADY, Carol GORMAL, Shirley A. FAIRHURST, and Barry E. SMITH. "Covalent modification of nitrogenase MoFe protein by ADP." Biochemical Journal 322, no. 3 (March 15, 1997): 737–44. http://dx.doi.org/10.1042/bj3220737.

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MgADP- reacted with the nitrogenase molybdenum–iron (MoFe) protein of Klebsiella pneumoniae (Kp1) over a period of 2 h to yield a stable, catalytically active conjugate. The isolated protein exhibited a new, broad 31P NMR resonance at -1 p.p.m. lacking phosphorus J coupling. The adenine ring of [8-14C]ADP remained associated with the conjugate. A covalently bound nucleotide was identified as AMP by NMR and TLC. Extended dialysis of Kp1 against MgADP- resulted in further AMP binding at the protein surface. ADP was initially bound tightly to Kp1 at a site distinct from the AMP sites. ATP did not replace ADP. The time course of the formation of the Kp1-AMP was altered by the nitrogenase iron protein (Kp2) and was dependent on redox potential. Kp1-AMP was stable to concentration and oxidation with ferricyanide ion at -350 mV. Slow hydrolysis of Kp1-AMP over a period of 6 h yielded AMP and unaltered Kp1. The adenine ring of ADP exchanged with adenine of MgATP2- during reductant-limited turnover of nitrogenase under N2, indicating reversibility of ATP hydrolysis at 15 °C. [32P]Pi exchanged with the terminal phosphate group of both ADP and ATP on incubation with Kp1. 32P exchange and the catalytic activity of Kp1 were inhibited by a 20-fold molar excess of the lysine-modifying reagent, o-phthalaldehyde (OPT). Preincubation with MgADP- protected against OPT inactivation. Two potentially reactive lysine residues on the α chain of the MoFe protein near a putative hydrophobic docking site for the nitrogenase Fe protein are proposed as sites of OPT and nucleotide binding. Azotobacter vinelandiiMoFe protein (Av1) also formed an AMP adduct but Kp2 did not. Catalase did not interact with ADP. The reactions of the nitrogenase MoFe protein with adenine nucleotides have no counterpart in known protein–nucleotide interactions.

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Polyakov, Maxim, Igor Khanin, Gennadiy Shevchenko, and Vladimir Bilozubenko. "Data mining as a cognitive tool: Capabilities and limits." Knowledge and Performance Management 5, no. 1 (July 8, 2021): 1–13. http://dx.doi.org/10.21511/kpm.05(1).2021.01.

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Due to the large volumes of empirical digitized data, a critical challenge is to identify their hidden and unobvious patterns, enabling to gain new knowledge. To make efficient use of data mining (DM) methods, it is required to know its capabilities and limits of application as a cognitive tool. The paper aims to specify the capabilities and limits of DM methods within the methodology of scientific cognition. This will enhance the efficiency of these DM methods for experts in this field as well as for professionals in other fields who analyze empirical data. It was proposed to supplement the existing classification of cognitive levels by the level of empirical regularity (ER) or provisional hypothesis. If ER is generated using DM software algorithm, it can be called the man-machine hypothesis. Thereby, the place of DM in the classification of the levels of empirical cognition was determined. The paper drawn up the scheme illustrating the relationship between the cognitive levels, which supplements the well-known schemes of their classification, demonstrates maximum capabilities of DM methods, and also shows the possibility of a transition from practice to the scientific method through the generation of ER, and further from ER to hypotheses, and from hypotheses to the scientific method. In terms of the methodology of scientific cognition, the most critical fact was established – the limitation of any DM methods is the level of ER. As a result of applying any software developed based on DM methods, the level of cognition achieved represents the ER level.

4

Gran, Christopher D., and Randolph M. Beaudry. "DETERMINATION OF LOW OXYGEN TOLERANCE LIMITS FOR SEVERAL APPLE CULTIVARS." HortScience 27, no. 6 (June 1992): 592g—593. http://dx.doi.org/10.21273/hortsci.27.6.592g.

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The oxygen partial pressure associated with the respiratory quotient (RQ) breakpoint (ie., lower oxygen limit) was determined for fruits of several apple cultivars stored at 0°C. Fruits were sealed in low density polyethylene pouches of various thicknesses and known permeability to determine O2 uptake, CO2 production, and respiratory quotients (RQ) at various O2 partial pressures. There were differences in the shape of O2 uptake versus steady state O2 curves between cultivars. While some cultivars showed steady declines in respiration rate from 8 kPa O2 to < 1 kPa, other cultivars showed no decline in respiration until O2 levels fell below 3 to 4 kPa. Fruits having elevated RQ values had greater levels of headspace ethanol in the polyethylene pouches, which confirmed anaerobic respiration. The lower oxygen limit ranged from a low of approximately 0.75 kPa for cultivars Northern Spy and Law Rome to high of 1.5 kPa for McIntosh.

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LaPorte, Norman H. "‘Stalinization’ and its Limits in the Saxon KPD, 1925–28." European History Quarterly 31, no. 4 (October 2001): 549–90. http://dx.doi.org/10.1177/026569140103100403.

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Ding, Chao, Cornelis van ’t Veer, Joris J. T. H. Roelofs, Meenal Shukla, Keith R. McCrae, Alexey S. Revenko, Jeff Crosby, and Tom van der Poll. "Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis." American Journal of Physiology-Lung Cellular and Molecular Physiology 314, no. 3 (March 1, 2018): L397—L405. http://dx.doi.org/10.1152/ajplung.00288.2017.

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High-molecular-weight kininogen (HK), together with factor XI, factor XII and prekallikrein, is part of the contact system that has proinflammatory, prothrombotic, and vasoactive properties. We hypothesized that HK plays a role in the host response during pneumonia-derived sepsis. To this end mice were depleted of kininogen (KNG) to plasma HK levels of 28% of normal by repeated treatment with a specific antisense oligonucleotide (KNG ASO) for 3 wk before infection with the common human sepsis pathogen Klebsiella pneumoniae via the airways. Whereas plasma HK levels increased during infection in mice treated with a scrambled control ASO (Ctrl ASO), HK level in the KNG ASO-treated group remained reduced to 25–30% of that in the corresponding Ctrl ASO group both before and after infection. KNG depletion did not influence bacterial growth in lungs or dissemination to distant body sites. KNG depletion was associated with lower lung CXC chemokine and myeloperoxidase levels but did not impact neutrophil influx, lung pathology, activation of the vascular endothelium, activation of the coagulation system, or the extent of distant organ injury. These results were corroborated by studies in mice with a genetic deficiency of KNG, which were indistinguishable from wild-type mice during Klebsiella-induced sepsis. Both KNG depletion and KNG deficiency were associated with strongly reduced plasma prekallikrein levels, indicating the carrier function of HK for this zymogen. This study suggests that KNG does not significantly contribute to the host defense during gram-negative pneumonia-derived sepsis.

7

Kotorov, Radoslav P. "Virtual organization: conceptual analysis of the limits of its decentralization." Knowledge and Process Management 8, no. 1 (January 2001): 55–62. http://dx.doi.org/10.1002/kpm.93.

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Jeong, Yong Geun, Tae Hyo Kim, Chang Min Lee, Ki Shik Shim, In Kyu Moon, Sang-Il Lee, Woon Tae Jung, and Ok Jae Lee. "A Case of Limited Wegener's Granulomatosis with Gastroenteritis and Mesenteric Lymphadenopathy." Korean Journal of Gastroenterology 55, no. 5 (2010): 331. http://dx.doi.org/10.4166/kjg.2010.55.5.331.

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9

Smith, A. "Cephalopod sucker design and the physical limits to negative pressure." Journal of Experimental Biology 199, no. 4 (April 1, 1996): 949–58. http://dx.doi.org/10.1242/jeb.199.4.949.

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Two factors determine the strength of pressure-based adhesive mechanisms such as suction: the magnitude of the pressure differential that their musculature and mechanics can produce and the pressure differential that water can sustain. This paper compares the adhesive strength of the primary cephalopod sucker types: the stalked suckers of decapods (cuttlefish and squid) and the unstalked suckers of octopods. These results are compared with the physical limits imposed by cavitation, the failure of water under negative pressure. The maximum pressure differentials that suckers can produce were measured using a wettable pressure transducer or by measuring their force of attachment on a wettable surface and dividing by the area exposed to reduced pressure. The maximum pressure differentials that water can sustain on a typical marine surface were measured in a Z-tube. Fifteen cephalopod species representing three orders were studied. At sea level, cavitation limits all suckers to the same range of pressure differentials (100-200 kPa), regardless of their morphology. As ambient pressure increases with depth, cavitation ceases to be limiting. In this case, stalked decapod suckers produce greater pressure differentials than unstalked octopod suckers. In addition, small suckers produce greater pressure differentials than large suckers. Suckers larger than 7.5 mm2, both decapod and octopod, typically achieve pressure differentials of 100 kPa. As their size decreases below 7.5 mm2, octopod suckers get slightly stronger, sometimes producing pressure differentials of 250-300 kPa, while decapod suckers get exponentially stronger, sometimes producing pressure differentials near 800 kPa. There were no differences in sucker strength among the four octopod species, but seven of the ten decapod species differed from the overall decapod regression curve. The strongest suckers belonged to the fast-swimming, open-water species in the decapod sub-order Oegopsida.

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Nicholson, Wayne L., Patricia Fajardo-Cavazos, Jeffrey Fedenko, José L. Ortíz-Lugo, Andrea Rivas-Castillo, Samantha M. Waters, and Andrew C. Schuerger. "Exploring the Low-Pressure Growth Limit: Evolution of Bacillus subtilis in the Laboratory to Enhanced Growth at 5 Kilopascals." Applied and Environmental Microbiology 76, no. 22 (October 1, 2010): 7559–65. http://dx.doi.org/10.1128/aem.01126-10.

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ABSTRACT Growth of Bacillus subtilis cells, normally adapted at Earth-normal atmospheric pressure (∼101.3 kPa), was progressively inhibited by lowering of pressure in liquid LB medium until growth essentially ceased at 2.5 kPa. Growth inhibition was immediately reversible upon return to 101.3 kPa, albeit at a slower rate. A population of B. subtilis cells was cultivated at the near-inhibitory pressure of 5 kPa for 1,000 generations, where a stepwise increase in growth was observed, as measured by the turbidity of 24-h cultures. An isolate from the 1,000-generation population was obtained that showed an increase in fitness at 5 kPa when compared to the ancestral strain or a strain obtained from a parallel population that evolved for 1,000 generations at 101.3 kPa. The results from this preliminary study have implications for understanding the ability of terrestrial microbes to grow in low-pressure environments such as Mars.

11

Kayabali, Kamil, and Osman Oguz Tufenkci. "Shear strength of remolded soils at consistency limits." Canadian Geotechnical Journal 47, no. 3 (March 2010): 259–66. http://dx.doi.org/10.1139/t09-095.

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The undrained shear strength of remolded soils is of concern in certain geotechnical engineering applications. Several methods for determining this parameter exist, including the laboratory vane test. This study proposes a new method to estimate the undrained shear strength, particularly at the plastic and liquid limits. For 30 inorganic soil samples of different plasticity levels, we determined the Atterberg limits, then performed a series of reverse extrusion tests at different water contents. The plastic and liquid limits are derived from the linear relationship between the logarithm of the extrusion pressure and water content. The tests show that the average undrained shear strength determined from the extrusion pressures at the plastic limit is about 180 kPa, whereas the average undrained shear strength at the liquid limit is 2.3 kPa. We show that the undrained shear strength of remolded soils at any water content can be estimated from the Atterberg limits alone. Although the laboratory vane test provides a reasonable undrained shear strength value at the plastic limit, it overestimates the undrained shear strength at the liquid limit and thus, care must be taken when the laboratory vane test is used to determine undrained shear strengths at water contents near the liquid limit.

12

Liu, Liang, Jin Zhang, Frank E. Rheindt, Fumin Lei, Yanhua Qu, Yu Wang, Yu Zhang, et al. "Genomic evidence reveals a radiation of placental mammals uninterrupted by the KPg boundary." Proceedings of the National Academy of Sciences 114, no. 35 (August 14, 2017): E7282—E7290. http://dx.doi.org/10.1073/pnas.1616744114.

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The timing of the diversification of placental mammals relative to the Cretaceous–Paleogene (KPg) boundary mass extinction remains highly controversial. In particular, there have been seemingly irreconcilable differences in the dating of the early placental radiation not only between fossil-based and molecular datasets but also among molecular datasets. To help resolve this discrepancy, we performed genome-scale analyses using 4,388 loci from 90 taxa, including representatives of all extant placental orders and transcriptome data from flying lemurs (Dermoptera) and pangolins (Pholidota). Depending on the gene partitioning scheme, molecular clock model, and genic deviation from molecular clock assumptions, extensive sensitivity analyses recovered widely varying diversification scenarios for placental mammals from a given gene set, ranging from a deep Cretaceous origin and diversification to a scenario spanning the KPg boundary, suggesting that the use of suboptimal molecular clock markers and methodologies is a major cause of controversies regarding placental diversification timing. We demonstrate that reconciliation between molecular and paleontological estimates of placental divergence times can be achieved using the appropriate clock model and gene partitioning scheme while accounting for the degree to which individual genes violate molecular clock assumptions. A birth-death-shift analysis suggests that placental mammals underwent a continuous radiation across the KPg boundary without apparent interruption by the mass extinction, paralleling a genus-level radiation of multituberculates and ecomorphological diversification of both multituberculates and therians. These findings suggest that the KPg catastrophe evidently played a limited role in placental diversification, which, instead, was likely a delayed response to the slightly earlier radiation of angiosperms.

13

Cooperstock, F. I. "Weak-field general relativistic dynamics and the Newtonian limit." Modern Physics Letters A 31, no. 05 (February 5, 2016): 1650037. http://dx.doi.org/10.1142/s0217732316500371.

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We show that the generally held view that the gravity of weak-field nonrelativistic-velocity sources being invariably almost equivalent to Newtonian gravity (NG) (the “Newtonian limit” approach) is in some instances misleading and in other cases incorrect. A particularly transparent example is provided by comparing the Newtonian and general relativistic analyses of a simple variant of van Stockum’s infinite rotating dust cylinder. We show that some very recent criticisms of our work that had been motivated by the Newtonian limit approach were incorrect and note that no specific errors in our work were found in the critique. In the process, we underline some problems that arise from inappropriate coordinate transformations. As further support for our methodology, we note that our weak-field general relativistic treatment of a model galaxy was vindicated recently by the observations of Xu et al. regarding our prediction that the Milky Way was 19–21 kpc in radius as opposed to the commonly held view that the radius was 15 kpc.

14

Fisher, K., D. J. Lower, and R. N. Pau. "Klebsiella pneumoniae nitrogenase MoFe protein: chymotryptic proteolysis affects function by limited cleavage of the β-chain and provides high-specific-activity MoFe protein." Biochemical Journal 291, no. 1 (April 1, 1993): 309–14. http://dx.doi.org/10.1042/bj2910309.

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Proteinase treatment with chymotrypsin has been used to probe the structure of native Klebsiella pneumoniae nitrogenase MoFe protein (Kp1). Reaction with chymotrypsin did not bleach Kp1, suggesting that it did not destroy the metal centres, and the Mo and Fe contents of Kp1 were unchanged. High ratios of chymotrypsin to Kp1 (1:1 by mass) cleaved the beta-chain of Kp1 to give 44 and 14 kDa polypeptides, which N-terminal amino acid sequence analysis showed to be derived from cleavage at residue beta-Phe124. A mutant MoFe protein, Kp1Met-124, in which beta-Phe124 is replaced by methionine, was not cleaved by chymotrypsin. Under non-denaturing conditions, the ‘nicked’ beta-chain of the wild-type protein remained associated with the alpha-chain. The alpha-chain was not cleaved by the proteinase treatment. Fission of the wild-type beta-chain was accompanied by loss of enzyme activity, loss of intensity of the g = 3.7 e.p.r. signal derived from dithionite-reduced FeMoco and by changes in the visible spectrum. The e.p.r. spectra of potassium ferricyanide-oxidized native and digested Kp1 show differences in the signals between g = 1.6 and 2.0. After prolonged treatment, the final specific activity of Kp1 was about 25 +/- 5% of the initial activity. This corresponded to 25 +/- 5% of the beta-chain which was resistant to proteolytic action. Brief treatment of Kp1 with a lower concentration of chymotrypsin (chymotrypsin/Kp1 ratio = 1:10 by mass, for 10 min) preferentially cleaved high-molecular-mass polypeptides that routinely contaminate preparations of Kp1 prepared by standard procedures. Treatment with chymotrypsin followed by gel filtration to remove the proteinase and cleaved protein fragments can therefore be used to increase significantly the specific activity of Kp1 preparations and remove contaminating activities, such as the ATPase activity of myokinase.

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Joles, Dennis W., P. Chowdary Talasila, and Arthur C. Cameron. "MODIFIED-ATMOSPHERE PACKAGING OF SMALL FRUITS: THE INFLUENCE OF CO2 ON O2 UPTAKE AND THE LOWER O2 LIMIT." HortScience 28, no. 5 (May 1993): 511a—511. http://dx.doi.org/10.21273/hortsci.28.5.511a.

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For raspberry (Rubus idaeus L. `Heritage'), blueberry (Vaccinium corymbosum L. `Jersey') and sweet cherry (Prunus avium L. `Sams') fruit, CaO, as a CO2 scrubber, was combined with modified-atmosphere packaging to generate a range of steady-state O2 levels (≈13 to 1 kPa) over which CO2 accumulated (≈3 to 17 kPa) or was scrubbed (≤ .1 kPa). The steady-state O2 levels in the presence and absence of generated CO2 were similar. Since steady-state O2 levels are a direct function of a fruit's O2 uptake in a modified-atmosphere package, we concluded that the CO2 levels generated had no effect on O2 uptake. The O2 level at which an increase in headspace ethanol was observed also did not differ in packages with and without a CO2 scrubber. For raspberry fruit, supplemental CO2 levels of 10, 20 and 60 kPa were added to sealed packages. The levels of steady-state O2 and CO2 were measured and the rates O2 uptake and CO2 production estimated. It was found that supplemental CO2 levels up to 20 kPa had little effect on fruit O2 uptake.

16

Kim, Kwang Min, and Jong Kyun Lee. "Is Limited Endoscopic Sphincterotomy with Large Balloon Dilation Safer and More Effective than Standard Endoscopic Sphincterotomy?" Korean Journal of Gastroenterology 62, no. 6 (2013): 382. http://dx.doi.org/10.4166/kjg.2013.62.6.382.

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Gran, Christopher D., and Randolph M. Beaudry. "MODIFIED ATMOSPHERE PACKAGING DETERMINATION OF THE LOW OXYGEN LIMIT OF APPLE FRUIT BY HEADSPACE ETHANOL ACCUMULATION." HortScience 28, no. 5 (May 1993): 446b—446. http://dx.doi.org/10.21273/hortsci.28.5.446b.

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`Red Delicious', `Golden Delicious', `Marshall McIntosh', and `Redmax McIntosh' apple (Malus domestica, Borkh.) fruit were sealed in low density polyethylene packages and stored at 0 to 25°C (3 to 25°C for `McIntosh' strains) until steady-state respiration occurred. O2and CO2 partial pressures for packages were determined, after which headspace EtOH samples were drawn from packages with a range of O2 partial pressures. The lower O2 limit for each variety over the range of temperatures was determined by elevated EtOH levels. As temperatures increased, the minimum O2 partial pressure at which EtOH accumulated increased. Temperature effects varied with cultivars. In the case of `Golden Delicious' the lower O2 limit (determined by EtOH accumulation) ranged from 0.57 kPa at 0° C to 0.80 kPa at 25°C, while for `Marshall McIntosh' low O2 limit values ranged from 1.2 kPa at 3°C to 6.4 kPa at 25°C. Macerated tissue EtOH levels mimicked headspace EtOH levels, and headspace accumulation of EtOH with time indicated active fermentation of tissues.

18

Liang, E. P. "New Distance Limit for the 3-5-79 Source." Symposium - International Astronomical Union 125 (1987): 549. http://dx.doi.org/10.1017/s0074180900161340.

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We provide new distance limits for the March 5, 1979 gamma ray transient source based on the synchrotron interpretation and the lack of low frequency self-absorption cutoff. This leads to upper limits of 0.6–11 kpc for emission areas ranging from 1 squared km polar caps to a 10 km radius stellar surface.

19

Patout, Maxime, Gill Arbane, Antoine Cuvelier, Jean Francois Muir, Nicholas Hart, and Patrick Brian Murphy. "Polysomnography versus limited respiratory monitoring and nurse-led titration to optimise non-invasive ventilation set-up: a pilot randomised clinical trial." Thorax 74, no. 1 (March 30, 2018): 83–86. http://dx.doi.org/10.1136/thoraxjnl-2017-211067.

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Polysomnography (PSG) is recommended for non-invasive ventilation (NIV) set-up in patients with chronic respiratory failure. In this pilot randomised clinical trial, we compared the physiological effectiveness of NIV set-up guided by PSG to limited respiratory monitoring (LRM) and nurse-led titration in patients with COPD–obstructive sleep apnoea (OSA) overlap. The principal outcome of interest was change in daytime arterial partial pressure of carbon dioxide (PaCO2) at 3 months. Fourteen patients with daytime PaCO2 >6 kPa and body mass index >30 kg/m2 were recruited. At 3 months, PaCO2 was reduced by −0.88 kPa (95% CI −1.52 to −0.24 kPa) in the LRM group and by −0.36 kPa (95% CI −0.96 to 0.24 kPa) in the PSG group. These pilot data provide support to undertake a clinical trial investigating the clinical effectiveness of attended limited respiratory monitoring and PSG to establish NIV in patients with COPD–OSA overlap.Trial numberResults, NCT02444806.

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Hussein, Abbas Khammas. "Parametric optimization of wt.% Y2O3 modified chromium-aluminide coatings using utility concept-based Taguchi approach." Multidiscipline Modeling in Materials and Structures 13, no. 3 (October 9, 2017): 448–63. http://dx.doi.org/10.1108/mmms-04-2017-0020.

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Purpose The purpose of this paper is to obtain a single setting (optimal setting) of various input parameters of pack cementation process, i.e. halide salt activator, powder of master alloy and wt% of Y2O3 to obtain a single output characteristic as a whole namely resistance of hot corrosion for T91 steel. Design/methodology/approach The multi-criterion methodology based on Taguchi approach and utility concept has been used for optimization of the multiple performance characteristics namely hot corrosion rate KP1, KP2 and KP3 for pack cementation coated T91 steel in chlorine and vanadium environment. Findings All the three pack cementation parameters, namely, halide salt activator, powder of master alloy and wt% of Y2O3 had a significant effect on the utility function based on analysis of variance for multiple performances. The percentage contribution of halide activator (1.54 percent), master alloy powder (4.66 percent) and wt% Y2O3 (93.79 percent). The results indicated the beneficial influence of yttrium on the chemical stability of the protective layer in presence of chlorine and vanadium environments. The optimal parameter settings obtained in this study is A2B2C1, i.e. halide salt activator (NaCl), powder of master alloy (92Cr-8Al) and 1wt% of Y2O3. Research limitations/implications The outcome of this study shall be useful to explore the possible use of the developed coating for high temperature components. Unfortunately, the pack cementation was normally limited by the diffusion and reaction kinetics involved, which has a detrimental effect on the mechanical properties of work pieces. Therefore, reducing pack cementation temperature is required for widespread application of the pack coatings. Social implications Pack coating at optimum conditions can be used for surface coating technologies to economically improve high temperature oxidation, corrosion resistance of components. Originality/value The multi-criterion methodology based on Taguchi approach and utility concept has been used for first time for parametric optimization of wt% Y2O3 modified chromium- aluminide coatings for T91 steel.

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Turick, Volodymyr M. "EFFICIENCY OF VORTICAL AND JET CONTROL OF CURRENT STRUCTURE IN LIMITED SWIRLING FLOWS." KPI Science News, no. 5-6 (October 15, 2019): 54–70. http://dx.doi.org/10.20535/kpi-sn.2019.5.178246.

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Huang, Bo, Anyang Wu, Shuang Zhang, Jiawei Wang, Bing Cao, Yihan Du, and Yue Zhang. "Design and Mechanical Properties of Flat Anchorage Limit Plate." Applied Sciences 13, no. 9 (May 3, 2023): 5638. http://dx.doi.org/10.3390/app13095638.

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To address the safety problems caused by clips being squeezed by jacks and wire slipping in the tensioning process of flat anchorages, we designed a limit plate to be used with a flat anchorage, and we studied the mechanical properties of the anchorage system after adding the limit plate through numerical simulation. Lastly, the limit plate was created and applied in a practical engineering scenario to test its safety performance. The results showed that the newly designed limit plate changed the butt position of the jack during tension, increased the hole distance, and hid the clips in the hole position of the limit plate, thus mitigating the safety hazard caused by the narrow surface tension construction in practice. The limit plate alleviated the stress concentration on the anchorage, and the extreme stress value decreased by 10–13%. Adverse effects, such as stress concentration caused by tension, were transferred to the replaceable limit plate, thus improving the reliability of the flat anchorage. The symmetrical tensioning scheme represented by sequential tensioning of holes 1, 4, 2, 5, and 3 is recommended, which produced the lowest extreme stress value of 685.55 kPa, which is 22.42 kPa lower than the maximum value of various other schemes.

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Lai, Wei, Yongjie Xu, Lin Liu, Huijun Cao, Bin Yang, Jie Luo, and Ying Fei. "Simultaneous and Visual Detection of KPC and NDM Carbapenemase-Encoding Genes Using Asymmetric PCR and Multiplex Lateral Flow Strip." Journal of Analytical Methods in Chemistry 2023 (July 22, 2023): 1–13. http://dx.doi.org/10.1155/2023/9975620.

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Carbapenem-resistant Enterobacteriaceae (CRE) infections constitute a threat to public health, and KPC and NDM are the major carbapenemases of concern. Rapid diagnostic tests are highly desirable in point-of-care (POC) and emergency laboratories with limited resources. Here, we developed a multiplex lateral flow assay based on asymmetric PCR and barcode capture probes for the simultaneous detection of KPC-2 and NDM-1. Biotinylated barcode capture probes corresponding to the KPC-2 and NDM-1 genes were designed and cast onto two different sensing zones of a nitrocellulose membrane after reacting with streptavidin to prepare a multiplex lateral flow strip. Streptavidin-coated gold nanoparticles (SA-AuNPs) were used as signal reporters. In response to the target carbapenemase genes, biotin-labelled ssDNA libraries were produced by asymmetric PCR, which bond to SA-AuNPs via biotin and hybridise with the barcode capture probe via a complementary sequence, thereby bridging SA-AuNPs and the barcode capture probe to form visible red lines on the detection zones. The signal intensities were proportional to the number of resistance genes tested. The strip sensor showed detection limits of 0.03 pM for the KPC-2 and 0.07 pM for NDM-1 genes, respectively, and could accurately distinguish between KPC-2 and NDM-1 genes in CRE strains. For the genotyping of clinical isolates, our strip exhibited excellent consistency with real-time fluorescent quantitative PCR and gene sequencing. Given its simplicity, cost-effectiveness, and rapid analysis accomplished by the naked eye, the multiplex strip is promising auxiliary diagnostic tool for KPC-2 and NDM-1 producers in routine clinical laboratories.

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JONG, E. DE, D. F. ACTON, and H. B. STONEHOUSE. "ESTIMATING THE ATTERBERG LIMITS OF SOUTHERN SASKATCHEWAN SOILS FROM TEXTURE AND CARBON CONTENTS." Canadian Journal of Soil Science 70, no. 4 (November 1, 1990): 543–54. http://dx.doi.org/10.4141/cjss90-057.

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The soil water contents at the liquid and plastic limits (the Atterberg limits) are widely used in the classification of soils for engineering purposes. Approximately 500 soil samples (129 Ap horizons and 417 B and C horizons) collected over several years as part of the ongoing soil survey program in Saskatchewan were analyzed for texture and Atterberg limits. On about half of the samples water retention (−33 kPa and −1500 kPa matric potential and air dryness), and organic and inorganic C were also determined. The relationship between the Atterberg limits and soil properties was explored through correlation and regression analysis. Clay and organic matter content explained most of the observed variation in the Atterberg limits of the Ap horizons. Clay was the most important independent variable in the B and C horizons, while inorganic C had only a relatively small impact. Key words: Atterberg limits, texture, organic and inorganic C

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Ruiz, Siul A., and Dani Or. "Biomechanical limits to soil penetration by earthworms: direct measurements of hydroskeletal pressures and peristaltic motions." Journal of The Royal Society Interface 15, no. 144 (July 2018): 20180127. http://dx.doi.org/10.1098/rsif.2018.0127.

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Burrows resulting from earthworm activity are important for supporting various physical and ecological soil processes. Earthworm burrowing activity is quantified using models for earthworm penetration and cavity expansion that consider soil moisture and mechanical properties. Key parameters in these models are the maximal pressures exerted by the earthworm's hydroskeleton (estimated at 200 kPa). We designed a special pressure chamber that directly measures the pressures exerted by moving earthworms under different confining pressures to delineate the limits of earthworm activity in soils at different mechanical and hydration states. The chamber consists of a Plexiglas prism fitted with inner flexible tubing that hosts the earthworm. The gap around the tubing is pressurized using water, and the earthworm's peristaltic motion and concurrent pressure fluctuations were recorded by a camera and pressure transducer. A model that links the earthworm's kinematics with measured pressure fluctuations was developed. Resulting maximal values of radial pressures for anecic and endogeic earthworms were 130 kPa and 195 kPa, respectively. Mean earthworm peristaltic frequencies were used to quantify burrowing rates that were in agreement with previous results. The study delineates mechanical constraints to soil bioturbation by earthworms by mapping the elastic behaviour in the measurement chamber onto the expected elasto-viscoplastic environment of natural soils.

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Jiang, Jian-Jie, and Zhen-Dong Cui. "Instability of High Liquid Limit Soil Slope for the Expressway Induced by Rainfall." Applied Sciences 12, no. 21 (October 26, 2022): 10857. http://dx.doi.org/10.3390/app122110857.

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The instability of high liquid limit soil slope is a common engineering problem in highway construction. This study focused on the slope at section K79 + 880 of the Guang-Le Expressway in Guangdong Province, China. In order to reduce the landslide and learn the mechanism of the high liquid limited soil slope, the effects of different rainfall intensities and rainfall time on the high liquid limit soil slope were studied by in-site monitoring and numerical simulation. According to the characteristics of the slope deformation and the monitoring data, the slope landslide is divided into three grades. Numerical simulation results show that the influence of rainfall intensity on the safety factor of high liquid limit soil slope is greater than that of rainfall time. The cumulative changes of Mises stress in Group B and Group C were −2.19 kPa and −2.91 kPa, respectively, and the cumulative decreases were −7.22% and −9.60%, respectively. The cumulative changes of Mises stress in Group B and Group C were −2.05 kPa and −4.32 kPa, respectively, and the cumulative decreases were −4.50% and −9.48%, respectively. With the increase of rainfall for 24 h, the safety factor of Group C decreased by an average of 0.0408, and with the increase of rainfall time, the safety factor increased, and the safety factor of 96 h of rainfall in Group C was 0.1249 lower than that of 24 h of rainfall. The greater the rainfall intensity, the greater the change of matrix suction at the top of the slope, and the more prone the top of the slope to shallow landslides. For the high liquid limit soil slope, slope instability phenomena such as surface flow collapse occur easily and have little impact on the deep sliding surface. The dimensionless displacement coefficient K is proposed to quantify the landslide displacement under different rainfall. A general method is proposed to measure the cumulative displacement of the K79 + 880 slope where the sensor is not placed.

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Seo, Geom Seog. "Determining the Dose of Azathioprine Based on the Lower Limit of Leukocyte Count in Patients with Crohn's Disease." Korean Journal of Gastroenterology 62, no. 2 (2013): 83. http://dx.doi.org/10.4166/kjg.2013.62.2.83.

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Dainton, Amanda N., Hulya Dogan, and Charles G. Aldrich. "PSV-B-27 The effects of carbohydrate hydrocolloids on firmness, toughness, and expressible moisture of wet pet food." Journal of Animal Science 99, Supplement_3 (October 8, 2021): 334. http://dx.doi.org/10.1093/jas/skab235.613.

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Abstract In a previous experiment, inclusion of guar gum, kappa carrageenan, locust bean gum, and xanthan gum were observed to influence the texture of wet pet food. However, limited published research has addressed their texture and water holding. Therefore, the objective was to quantify the differences in texture and expressible moisture (EM) due to common hydrocolloids in wet pet foods. Treatments included 1% dextrose (D) and 0.5% guar gum with either 0.5% dextrose (DG), 0.5% kappa carrageenan (KCG), 0.5% locust bean gum (LBG), or 0.5% xanthan gum (XGG) in a chicken-based product processed in three replicate batches. Processing occurred in a still retort at 121 °C and 144.79 kPa for an average 81.25 minute cook cycle and 79.58 minute cooling cycle. Texture analysis was conducted with a modified back extrusion while products remained in the can (n = 5) and firmness (peak force measurement) and toughness (positive area under the curve) were recorded during a 2 cm penetration. Expressible moisture was analyzed by centrifugal methods. Data were analyzed as a 1-way ANOVA with the fixed effect of treatment and the random effect of batch. Fisher’s LSD post hoc test was used to separate means. The KCG treatment exhibited the highest (P < 0.05) firmness (27.00 N) and D and DG the lowest (average 8.75 N) with LBG and XGG intermediate (average 15.59 N). More differentiation was noted in toughness, with D (67 N x mm) less tough (P < 0.05) than DG (117 N x mm). The D treatment had the highest (P < 0.05) EM (49.91%) and was the only treatment to separate into 2 phases. The LBG and XGG treatments had the lowest (P < 0.05) EM (average 16.54%) with DG and KCG intermediate (average 25.26%). Carbohydrate hydrocolloids utilize different mechanisms to provide structure, which likely caused the differences in texture and EM observed.

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Smith, Miranda Z., Tedi E. Asher, Vanessa Venturi, Miles P. Davenport, Daniel C. Douek, David A. Price, and Stephen J. Kent. "Limited Maintenance of Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8 T-Cell Receptor Clonotypes after Virus Challenge." Journal of Virology 82, no. 15 (May 28, 2008): 7357–68. http://dx.doi.org/10.1128/jvi.00607-08.

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ABSTRACT T-cell receptors (TCRs) govern the specificity, efficacy, and cross-reactivity of CD8 T cells. Here, we studied CD8 T-cell clonotypes from Mane-A*10 + pigtail macaques responding to the simian immunodeficiency virus (SIV) Gag KP9 epitope in a setting of vaccination and subsequent viral challenge. We observed a diverse TCR repertoire after DNA, recombinant poxvirus, and live attenuated virus vaccination, with none of 59 vaccine-induced KP9-specific TCRs being identical between macaques. The KP9-specific TCR repertoires remained diverse after SIV or simian-human immunodeficiency virus challenge but, remarkably, exhibited substantially different clonotypic compositions compared to the corresponding populations prechallenge. Within serial samples from individual pigtail macaques, only a small subset (33.9%) of TCRs induced by vaccination were maintained or expanded after challenge. Most (66.1%) of the TCRs induced by vaccination were not detectable after challenge. Our results suggest that some CD8 T cells induced by vaccination are more efficient than others at responding to a viral challenge. These findings have implications for future AIDS virus vaccine studies, which should consider the “fitness” of vaccine-induced T cells in order to generate robust responses in the face of virus exposure.

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BAE, Kidong, and Kiryong Kim. "Problems of Carbon Isotopes Dates under Basalt and lower Limit of Paleolithic Industries in the Hantan-Imjin River Basin." Journal of Korean Palaeolithic Society 38 (December 30, 2018): 5–19. http://dx.doi.org/10.52954/kps.2018.1.38.5.

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Bassetti, Matteo, and Maddalena Peghin. "How to manage KPC infections." Therapeutic Advances in Infectious Disease 7 (January 2020): 204993612091204. http://dx.doi.org/10.1177/2049936120912049.

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Carbapenemase-producing Enterobacteriaceae represent an increasing global threat worldwide and Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) has become one of the most important contemporary pathogens, especially in endemic areas. Risk stratification and rapid diagnostics laboratory workflows are of paramount importance and indication for therapy of KPC-KP infection must be individualized according to the baseline characteristics of the patient and severity of infection. The optimal treatment of infection because of KPC-KP organisms is uncertain and antibiotic options are limited. The knowledge of the patient’s pathophysiology, infection site, and application of the pharmacokinetic/pharmacodynamic principles on the basis of minimum inhibitory concentration (MIC) has progressively gained major relevance. Combination therapies including high-dose meropenem, colistin, fosfomycin, tigecycline, and aminoglycosides are widely used, with suboptimal results. In the past few years, new antimicrobials targeting KPC-KP have been developed and are now at various stages of clinical research. However, their optimal use should be guaranteed in the long term for delaying, as much as possible, the emergence of resistance. Strict infection control measures remain necessary. The aim of this review is to discuss the challenges in the management and treatment of patients with infections because KPC-KP and provide an expert opinion.

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Forgue, J., A. Legeay, and J. C. Massabuau. "Is the resting rate of oxygen consumption of locomotor muscles in crustaceans limited by the low blood oxygenation strategy?" Journal of Experimental Biology 204, no. 5 (March 1, 2001): 933–40. http://dx.doi.org/10.1242/jeb.204.5.933.

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Numerous water-breathers exhibit a gas-exchange regulation strategy that maintains O(2) partial pressure, P(O2), in the arterial blood within the range 1–3 kPa at rest during the daytime. In a night-active crustacean, we examined whether this could limit the rate of O(2)consumption (M(O2)) of locomotor muscles and/or the whole body as part of a coordinated response to energy conservation. In the crayfish Astacus leptodactylus, we compared the in vitro relationship between the M(O2) of locomotor muscles as a function of the extracellular P(O2) and P(CO2) and in vivo circadian changes in blood gas tensions at various values of water P(O2). In vitro, the M(O2) of locomotor muscle, either at rest or when stimulated with CCCP, was O(2)-dependent up to an extracellular P(O2) of 8–10 kPa. In vivo, the existence of a night-time increase in arterial P(O2) of up to 4 kPa at water P(O2) values of 20 and 40 kPa was demonstrated, but an experimental increase in arterial P(O2) during the day did not lead to any rise in whole-body M(O2). This suggested that the low blood P(O2) in normoxia has no global limiting effect on daytime whole-body M(O2). The participation of blood O(2) status in shaping the circadian behaviour of crayfish is discussed.

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Hsieh, Gen-Wen, Liang-Cheng Shih, and Pei-Yuan Chen. "Porous Polydimethylsiloxane Elastomer Hybrid with Zinc Oxide Nanowire for Wearable, Wide-Range, and Low Detection Limit Capacitive Pressure Sensor." Nanomaterials 12, no. 2 (January 14, 2022): 256. http://dx.doi.org/10.3390/nano12020256.

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We propose a flexible capacitive pressure sensor that utilizes porous polydimethylsiloxane elastomer with zinc oxide nanowire as nanocomposite dielectric layer via a simple porogen-assisted process. With the incorporation of nanowires into the porous elastomer, our capacitive pressure sensor is not only highly responsive to subtle stimuli but vigorously so to gentle touch and verbal stimulation from 0 to 50 kPa. The fabricated zinc oxide nanowire–porous polydimethylsiloxane sensor exhibits superior sensitivity of 0.717 kPa−1, 0.360 kPa−1, and 0.200 kPa−1 at the pressure regimes of 0–50 Pa, 50–1000 Pa, and 1000–3000 Pa, respectively, presenting an approximate enhancement by 21−100 times when compared to that of a flat polydimethylsiloxane device. The nanocomposite dielectric layer also reveals an ultralow detection limit of 1.0 Pa, good stability, and durability after 4000 loading–unloading cycles, making it capable of perception of various human motions, such as finger bending, calligraphy writing, throat vibration, and airflow blowing. A proof-of-concept trial in hydrostatic water pressure sensing has been demonstrated with the proposed sensors, which can detect tiny changes in water pressure and may be helpful for underwater sensing research. This work brings out the efficacy of constructing wearable capacitive pressure sensors based on a porous dielectric hybrid with stress-sensitive nanostructures, providing wide prospective applications in wearable electronics, health monitoring, and smart artificial robotics/prosthetics.

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Mark, F. C., C. Bock, and H. O. Pörtner. "Oxygen-limited thermal tolerance in Antarctic fish investigated by MRI and 31P-MRS." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 283, no. 5 (November 1, 2002): R1254—R1262. http://dx.doi.org/10.1152/ajpregu.00167.2002.

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The hypothesis of an oxygen-limited thermal tolerance was tested in the Antarctic teleost Pachycara brachycephalum. With the use of flow-through respirometry, in vivo31P-NMR spectroscopy, and MRI, we studied energy metabolism, intracellular pH (pHi), blood flow, and oxygenation between 0 and 13°C under normoxia (Po 2: 20.3 to 21.3 kPa) and hyperoxia (Po 2: 45 kPa). Hyperoxia reduced the metabolic increment and the rise in arterial blood flow observed under normoxia. The normoxic increase of blood flow leveled off beyond 7°C, indicating a cardiovascular capacity limitation. Ventilatory effort displayed an exponential rise in both groups. In the liver, blood oxygenation increased, whereas in white muscle it remained unaltered (normoxia) or declined (hyperoxia). In both groups, the slope of pHi changes followed the alpha-stat pattern below 6°C, whereas it decreased above. In conclusion, aerobic scope declines around 6°C under normoxia, marking the pejus temperature. By reducing circulatory costs, hyperoxia improves aerobic scope but is unable to shift the breakpoint in pH regulation or lethal limits. Hyperoxia appears beneficial at sublethal temperatures, but no longer beyond when cellular or molecular functions become disturbed.

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Sangik Lee. "On the Limits of Western Modern Economic Ideologies & the Reillumination about Confucian Right Name Theory." JOURNAL OF KOREAN PHILOSOPHICAL HISTORY ll, no. 40 (March 2014): 329–62. http://dx.doi.org/10.35504/kph.2014..40.013.

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Ekmekci Ertek, İrem, Hande Gazey, Saba Çiçek, and Selçuk Candansayar. "Stress levels of healthcare workers in the COVID-19 pandemic and relation to gender roles: Is the problem limited to the work? (eng)." Journal of Clinical Psychiatry 25, no. 1 (2022): 5–14. http://dx.doi.org/10.5505/kpd.2022.92668.

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Davies, R. I., M. Lehnert, A. J. Baker, and S. Rabien. "Diffraction Limited Imaging of High Redshift Galaxies with Adaptive Optics." Symposium - International Astronomical Union 205 (2001): 455–56. http://dx.doi.org/10.1017/s007418090022175x.

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The major cornerstone of future ground-based astronomy is imaging and spectroscopy at the diffraction limit using adaptive optics. To exploit the potential of current AO systems, we have begun a survey around bright stars to study intermediate redshift galaxies at high resolution. Using ALFA to reach the diffraction limit of the 3.5-m telescope at Calar Alto allows us to study the structure of distant galaxies in the near-infrared at scales of 100-150 pc for z=0.05 and at scales 1.0-1.5 kpc at z=1. In this contribution we present the initial results of this project, which hint at the exciting prospects possible with the resolution and sensitivity available using an AO camera on the 8-m class VLT.

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Furfaro, Anna Lisa, Giulia Loi, Caterina Ivaldo, Mario Passalacqua, Gabriella Pietra, Giovanni Enrico Mann, and Mariapaola Nitti. "HO-1 Limits the Efficacy of Vemurafenib/PLX4032 in BRAFV600E Mutated Melanoma Cells Adapted to Physiological Normoxia or Hypoxia." Antioxidants 11, no. 6 (June 14, 2022): 1171. http://dx.doi.org/10.3390/antiox11061171.

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Induction of heme oxygenase 1 (HO-1) favors immune-escape in BRAFV600 melanoma cells treated with Vemurafenib/PLX4032 under standard cell culture conditions. However, the oxygen tension under standard culture conditions (~18 kPa O2) is significantly higher than the physiological oxygen levels encountered in vivo. In addition, cancer cells in vivo are often modified by hypoxia. In this study, MeOV-1 primary melanoma cells bearing the BRAFV600E mutation, were adapted to either 5 kPa O2 (physiological normoxia) or 1 kPa O2 (hypoxia) and then exposed to 10 μM PLX4032. PLX4032 abolished ERK phosphorylation, reduced Bach1 expression and increased HO-1 levels independent of pericellular O2 tension. Moreover, cell viability was significantly reduced further in cells exposed to PLX4032 plus Tin mesoporphyrin IX, a HO-1 inhibitor. Notably, our findings provide the first evidence that HO-1 inhibition in combination with PLX4032 under physiological oxygen tension and hypoxia restores and increases the expression of the NK ligands ULBP3 and B7H6 compared to cells exposed to PLX4032 alone. Interestingly, although silencing NRF2 prevented PLX4032 induction of HO-1, other NRF2 targeted genes were unaffected, highlighting a pivotal role of HO-1 in melanoma resistance and immune escape. The present findings may enhance translation and highlight the potential of the HO-1 inhibitors in the therapy of BRAFV600 melanomas.

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Andrade, Kevin E., Jackson Fuson, Sophia Gad-Nasr, Demao Kong, Quinn Minor, M. Grant Roberts, and Manoj Kaplinghat. "A stringent upper limit on dark matter self-interaction cross-section from cluster strong lensing." Monthly Notices of the Royal Astronomical Society 510, no. 1 (November 12, 2021): 54–81. http://dx.doi.org/10.1093/mnras/stab3241.

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ABSTRACT We analyse strongly lensed images in eight galaxy clusters to measure their dark matter density profiles in the radial region between 10 kpc and 150 kpc, and use this to constrain the self-interaction cross-section of dark matter (DM) particles. We infer the mass profiles of the central DM haloes, bright central galaxies, key member galaxies, and DM subhaloes for the member galaxies for all eight clusters using the qlens code. The inferred DM halo surface densities are fit to a self-interacting dark matter model, which allows us to constrain the self-interaction cross-section over mass σ/m. When our full method is applied to mock data generated from two clusters in the Illustris-TNG simulation, we find results consistent with no dark matter self-interactions as expected. For the eight observed clusters with average relative velocities of $1458_{-81}^{+80}$ km s−1, we infer $\sigma /m = 0.082_{-0.021}^{+0.027} \rm cm^2\, g^{ -1}$ and $\sigma /m \lt 0.13~ \rm cm^2\, g^{ -1}$ at the 95 per cent confidence level.

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Lim, Chang Sup, Won Moon, Seun Ja Park, Moo In Park, Jeong Moon Choi, Jae Hoon Yoo, Jong Bin Kim, and Jun Sik Lee. "How Should Azathioprine Be Dosed in Crohn's Disease? A Novel Strategy of Maximum Dose-titration Based on the Lower Limit of Leukocyte Count and Tolerability." Korean Journal of Gastroenterology 62, no. 2 (2013): 111. http://dx.doi.org/10.4166/kjg.2013.62.2.111.

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Papadimitriou-Olivgeris, Matthaios, Fotini Fligou, Iris Spiliopoulou, Christina Bartzavali, Vasiliki Dodou, Sophia Vamvakopoulou, Kyriaki Koutsileou, et al. "Early KPC-Producing Klebsiella pneumoniae Bacteremia among Intensive Care Unit Patients Non-Colonized upon Admission." Polish Journal of Microbiology 66, no. 2 (June 28, 2017): 251–54. http://dx.doi.org/10.5604/01.3001.0010.7863.

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Among 140 patients colonized by KPC-producing Klebsiella pneumoniae (KPC-Kp) between fourth and seventh day of Intensive Care Unit stay, 24 developed bacteraemia immediately after colonization. Colistin-resistance of the colonizing isolate was the factor significantly associated with early KPC-Kp bacteraemia (P < 0.001; OR 6.6, 95% CI 2.4-18.4), a worrisome finding since infections by colistin-resistant isolates is associated with increased mortality due to limited remaining therapeutic options.

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Scott, T. C., Chandreyee Sengupta, P. Lagos, Aeree Chung, and O. Ivy Wong. "Resolved H i in two ultra-diffuse galaxies from contrasting non-cluster environments." Monthly Notices of the Royal Astronomical Society 503, no. 3 (February 11, 2021): 3953–64. http://dx.doi.org/10.1093/mnras/stab390.

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ABSTRACT We report on the first resolved H i observations of two blue ultra-diffuse galaxies (UDGs), using the Giant Metrewave Radio Telescope (GMRT). These observations add to the so-far limited number of UDGs with resolved H i data. The targets are from contrasting non-cluster environments: UDG-B1 is projected in the outskirts of Hickson Compact Group 25 and Secco-dI-2 (SdI-2) is an isolated UDG. These UDGs also have contrasting effective radii with Re of 3.7 kpc (similar to the Milky Way) and 1.3 kpc, respectively. SdI-2 has an unusually large $\frac{M_{\rm H\,{\small I}}}{M_*}$ ratio = 28.9, confirming a previous single dish H i observation. Both galaxies display H i morphological and kinematic signatures consistent with a recent tidal interaction, which is also supported by observations from other wavelengths, including optical spectroscopy. Within the limits of the observations’ resolution our analysis indicates that SdI-2 is dark matter dominated within its H i radius and this is also likely to be the case for UDG-B1. Our study highlights the importance of high spatial and spectral resolution H i observations for the study of the dark matter properties of UDGs.

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Brackmann, Auri, Rogério de Oliveira Anese, Vanderlei Both, Fabio Rodrigo Thewes, and Diniz Fronza. "Atmosfera controlada para o armazenamento de goiaba cultivar 'Paluma'." Revista Ceres 59, no. 2 (April 2012): 151–56. http://dx.doi.org/10.1590/s0034-737x2012000200001.

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A goiaba é uma fruta que apresenta alta perecibilidade, sendo o armazenamento em Atmosfera Controlada (AC) uma técnica que pode prolongar a vida pós-colheita, mantendo sua qualidade. O objetivo deste trabalho foi determinar a melhor condição de armazenamento em AC para a conservação da qualidade da goiaba, cultivar 'Paluma'. O experimento foi conduzido no Delineamento em Blocos ao Acaso, com os tratamentos: [1] 20,9 kPa O2 + 0,03 kPa CO2 (AR - testemunha); [2] 1,0 kPa O2 + 2,0 kPa CO2; [3] 2,0 kPa O2 + 2,0 kPa CO2; [4] 3,0 kPa O2 + 2,0 kPa CO2; e [5] 3,0 kPa O2 + 4,0 kPa CO2. Todos os frutos foram armazenados à temperatura de 8°C (±0,2) sob umidade relativa de 95% (±2,0). Após 28 dias de armazenamento, os frutos foram avaliados quanto às suas características físico-químicas. A melhor conservação da goiaba cultivar 'Paluma' em AC foi obtida com O2 entre 1 e 2 kPa, combinado com 2 kPa de CO2. Estas condições reduziram a degradação da coloração verde da epiderme, a perda de firmeza e de acidez e mantiveram a coloração da polpa com mais eficiência; porém, a alta ocorrência de podridões durante a vida de prateleira é o fator que limita o período de conservação desta goiaba.

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Mente, Eleni, Alexia Legeay, Dominic F. Houlihan, and Jean-Charles Massabuau. "Influence of oxygen partial pressures on protein synthesis in feeding crabs." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 284, no. 2 (February 1, 2003): R500—R510. http://dx.doi.org/10.1152/ajpregu.00193.2002.

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Many water-breathing animals have a strategy that consists of maintaining low blood Po 2 values in a large range of water oxygenation level (4–40 kPa). This study examines the postprandial changes in O2 consumption, arterial blood Po 2, and tissue protein synthesis in the shore crab Carcinus maenas in normoxic, O2-depleted, and O2-enriched waters to study the effects of this strategy on the O2 consumption and peptide bond formation after feeding. In normoxic water (21 kPa), the arterial Po 2 was 1.1 kPa before feeding and 1.2 kPa 24 h later. In water with a Po 2 of 3 kPa (arterial Po 2 0.6 kPa), postprandial stimulation of protein synthesis and O2 consumption were blocked. The blockade was partial at a water Po 2 of 4 kPa (arterial Po 2 0.8 kPa). An increase in environmental Po 2 (60 kPa, arterial Po 2 10 kPa) resulted in an increase in protein synthesis compared with normoxic rates. It is concluded that the arterial Po 2 spontaneously set in normoxic Carcinus limits the rates of protein synthesis. The rationale for such a strategy is discussed.

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Heijdra, YF, PN Dekhuijzen, CL van Herwaarden, and HT Folgering. "Differences between sniff mouth pressures and static maximal inspiratory mouth pressures." European Respiratory Journal 6, no. 4 (April 1, 1993): 541–46. http://dx.doi.org/10.1183/09031936.93.06040541.

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Measurements of static maximal inspiratory mouth pressure (PImax) and dynamic sniff mouth pressure (Psniff) are frequently used to assess inspiratory muscle strength. The aim of the present study was to examine, in 42 healthy subjects, the equivalence of PImax and Psniff, the influence of body posture on PImax and Psniff, and the effects of nasal patency and repeated manoeuvres on Psniff. PImax was significantly higher than Psniff, 11.05 +/- 0.42 versus 8.53 +/- 0.31 kPa. Because of the low agreement between PImax and Psniff, the two measurement methods were not interchangeable. The limits of agreement were 2.56 +/- 3.92 kPa. Sitting PImax was 11.05 +/- 0.42 kPa, and supine PImax was 9.36 +/- 0.41 kPa. Sitting and supine Psniff were 8.53 +/- 0.31 kPa and 7.52 +/- 0.33 kPa, respectively. Psniff performed with one nostril open instead of two, was higher: 9.67 +/- 0.32 kPa left and 9.62 +/- 0.32 kPa right versus 8.53 +/- 0.31 kPa when both nostrils were open. After 20-28 sniff manoeuvres, Psniff fell from 8.43 +/- 0.31 kPa to 7.83 +/- 0.30 kPa, suggesting some mechanism of inspiratory muscle fatigue. We conclude that measurement of sitting PImax yields the highest values for inspiratory muscle strength. The two measurement methods, Psniff and PImax, are not interchangeable. Measurement of Psniff is affected by nasal patency.

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Smith, Thomas R., and M. Bonner Denton. "A High-Pressure Inductively Coupled Plasma Torch." Applied Spectroscopy 41, no. 4 (May 1987): 654–57. http://dx.doi.org/10.1366/0003702874448607.

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An inductively coupled plasma (ICP) torch utilizing an extended coolant tube that tapers down to a small exit orifice designed to increase the pressure within the ICP torch is described. This torch design makes use of the advantages associated with higher torch operating pressures (including improved detection limits, increased sensitivity, and better plasma stability), without requiring major modifications to existing commercially available ICP torch box and matching networks. Detection limits obtained with the use of the new torch design are compared with those obtained from several commonly used torch designs using a commercially available torch box and spectrometer. A two- to sevenfold improvement in detection limits is observed through increasing torch operating pressure from 101.325 KPa (760 Torr, or atmospheric pressure) to 120 KPa (900 Torr).

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Hsu, Cheng-Er, Yen-Chun Liu, Ya-Ting Cheng, Wen-Juei Jeng, Rong-Nan Chien, Chun-Yen Lin, Dar-In Tai, and I.-Shyan Sheen. "Hepatitis B Co-Infection Has Limited Impact on Liver Stiffness Regression in Chronic Hepatitis C Patients Treated with Direct-Acting Antivirals." Viruses 14, no. 4 (April 10, 2022): 786. http://dx.doi.org/10.3390/v14040786.

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Introduction: High sustained virological response (SVR) rate (>95%) and liver stiffness regression can be achieved with direct acting antivirals treatment (DAA) in patients with chronic hepatitis C virus (CHC) infection. Reactivation of hepatitis B virus (HBV) was reported during DAA treatment in patients co-infected with HBV, although its impact on liver stiffness remains unknown. This study aims to investigate whether the liver stiffness (LSM) regression is different between HBV/HCV co-infected and mono-HCV-infected patients. Materials and Methods: CHC patients with/without HBV co-infection who received DAA treatment and achieved SVR12 between March 2015 and December 2019 in Chang Gung Memorial Hospital, Linkou branch were prospectively enrolled. LSM was assessed by transient elastography (TE, Fibroscan) at baseline and after SVR. Propensity score matching (PSM) at 3:1 ratio, adjusted for age, gender, pre-DAA alanine aminotransferase (ALT), platelet count, and LSM, between CHC with and without HBV co-infection, was performed before further analysis. Results: Among 906 CHC patients enrolled, 52 (5.7%) patients had HBV/HCV co-infection. Patients with HBV/HCV co-infection were of younger age (61.8 vs. 63.2, p = 0.31), with a higher proportion of males (53.8% vs. 38.9%, p = 0.03), and lower pretreatment LSM level (8.15 vs. 10.2 kPa, p = 0.09), while other features were comparable. After PSM, patients with HBV/HCV co-infection had insignificantly lower LSM regression compared to mono-HCV-infected patients (−0.85 kPa vs. −1.65 kPa, p = 0.250). Conclusions: The co-infection of HBV among CHC patients has limited impact on liver stiffness regression after successful DAA treatment.

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Leavitt, Azita, Yehuda Carmeli, Inna Chmelnitsky, Moran G. Goren, Itzhak Ofek, and Shiri Navon-Venezia. "Molecular Epidemiology, Sequence Types, and Plasmid Analyses of KPC-Producing Klebsiella pneumoniae Strains in Israel." Antimicrobial Agents and Chemotherapy 54, no. 7 (March 29, 2010): 3002–6. http://dx.doi.org/10.1128/aac.01818-09.

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ABSTRACT Sporadic isolates of carbapenem-resistant KPC-2-producing Klebsiella pneumoniae were isolated in Tel Aviv Medical Center during 2005 and 2006, parallel to the emergence of the KPC-3-producing K. pneumoniae sequence type 258 (ST 258). We aimed to study the molecular epidemiology of these isolates and to characterize their bla KPC-carrying plasmids and their origin. Ten isolates (8 KPC-2 and 2 KPC-3 producing) were studied. All isolates were extremely drug resistant. They possessed the bla KPC gene and varied in their additional beta-lactamase contents. The KPC-2-producing strains belonged to three different sequence types: ST 340 (n = 2), ST 277 (n = 2), and a novel sequence type, ST 376 (n = 4). Among KPC-3-producing strains, a single isolate (ST 327) different from ST 258 was identified, but both strains carried the same plasmid (pKpQIL). The KPC-2-encoding plasmids varied in size (45 to 95 kb) and differed among each of the STs. Two of the Klebsiella bla KPC-2-carrying plasmids were identical to plasmids from Escherichia coli, suggesting a common origin of these plasmids. These data indicate that KPC evolution in K. pneumoniae is related to rare events of interspecies spread of bla KPC-2-carrying plasmids from E. coli followed by limited clonal spread, whereas KPC-3 carriage in this species is related almost strictly to clonal expansion of ST 258 carrying pKpQIL.

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Bonfochi Vinhaes, Vinicius, Gordon McTaggart-Cowan, Sandeep Munshi, Mahdi Shahbakhti, and Jeffrey D. Naber. "Experimental Studies of Low-Load Limit in a Stoichiometric Micro-Pilot Diesel Natural Gas Engine." Energies 15, no. 3 (January 19, 2022): 728. http://dx.doi.org/10.3390/en15030728.

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While operating at light loads, diesel pilot-ignited natural gas engines with lean premixed natural gas suffer from poor combustion efficiency and high methane emissions. This work investigates the limits of low-load operation for a micro-pilot diesel natural gas engine that uses a stoichiometric mixture to enable methane and nitrogen oxide emission control. By optimizing engine hardware, operating conditions, and injection strategies, this study focused on defining the lowest achievable load while maintaining a stoichiometric equivalence ratio and with acceptable combustion stability. A multi-cylinder diesel 6.7 L engine was converted to run natural gas premix with a maximum diesel micro-pilot contribution of 10%. With a base diesel compression ratio of 17.3:1, the intake manifold pressure limit was 80 kPa(absolute). At a reduced compression ratio of 15:1, this limit increased to 85 kPa, raising the minimum stable load. Retarding the combustion phasing, typically used in spark-ignition engines to achieve lower loads, was also tested but found to be limited by degraded diesel ignition at later timings. Reducing the pilot injection pressure improved combustion stability, as did increasing pilot quantity at the cost of lower substitution ratios. The lean operation further reduced load but increased NOx and hydrocarbon emissions. At loads below the practical dual-fuel limit, a transition to lean diesel operation will likely be required with corresponding implications for the aftertreatment system.

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Franke, Alberto, Osvaldo König, Luiz Carlos Pittol Martini, Eder João Pozzebon, and Roberto Liberalesso. "CONSUMO DE ÁGUA NA CULTURA DA BATATA SOB TRÊS NÍVEIS DE MANEJO DA UMIDADE DO SOLO." Ciência Rural 24, no. 1 (1994): 29–33. http://dx.doi.org/10.1590/s0103-84781994000100007.

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RESUMO O experimento foi conduzido no campo experimental do Centro de Ciências Rurais da Universidade Federal de Santa Maria, RS. Determinou-se o consumo de água no ciclo e nos diversos subperíodos de desenvolvimento, através do método do balanço hídrico. 0s resultados indicam que: a) os subperíodos de maior exigência hídrica são a estolonização, tuberização e desenvolvimento de tubérculos; b) o consumo hídrico no ciclo foi de 524,9mm, 493,8mm e 348,5mm para os tratamentos com limite inferior de disponibilidade hídrica à uma tensão de 45 kPa, 85 kPa e testemunha sem irrigação, respectivamente.

Journal articles on the topic 'Limite KPg'

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