Academic literature on the topic 'Lignée humaine'
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Journal articles on the topic "Lignée humaine"
Tijus, Charles. "Après-propos. L’intelligence artificielle : une autre intelligence ?" Enfance N° 1, no. 1 (March 28, 2024): 51–60. http://dx.doi.org/10.3917/enf2.241.0051.
Full textKelly, James. "Penser les paysages avec les trois synthèses du temps de Deleuze." Journal of French and Francophone Philosophy 29, no. 1-2 (December 10, 2021): 130–47. http://dx.doi.org/10.5195/jffp.2021.965.
Full textGavrilova, Natalia S., and Leonid A. Gavrilov. "Étude biodémographique des déterminants familiaux de la longévité humaine." Population Vol. 56, no. 1 (January 1, 2001): 225–51. http://dx.doi.org/10.3917/popu.p2001.56n1-2.0251.
Full textBadie, C., J. Bourhis, J. Bosq, H. Haddada, M. Chiron, A. Virone, and G. Vassal. "Transfert du gène p53 sauvage dans une lignée humaine de carcinome épidermoïde." Cancer/Radiothérapie 2, no. 5 (September 1998): 549–50. http://dx.doi.org/10.1016/s1278-3218(98)80073-5.
Full textHajok, Alicja, and Katarzyna Gabrysiak. "Les verbes supports et autres actualisateurs du prédicat nominal "comparaison" dans un texte scientifique." Neophilologica 2019 34 (December 14, 2022): 1–19. http://dx.doi.org/10.31261/neo.2022.34.11.
Full textPradier, O., D. Laurent, H. Schmidberger, M. Rave-Frank, K. Rubisch, M. Krebeck, E. Weiss, and C. F. Hess. "Étude in vitro de l'association paclitaxel-radiothérapie sur une lignée cellulaire tumorale épidermoïde humaine." Cancer/Radiothérapie 3, no. 1 (January 1999): 51–56. http://dx.doi.org/10.1016/s1278-3218(99)80034-1.
Full textLequien, Valérie. "Essai de phase II pour le facteur VIII recombinant dérivé d’une lignée cellulaire humaine." Actualités Pharmaceutiques Hospitalières 6, no. 24 (November 2010): 8. http://dx.doi.org/10.1016/s1769-7344(10)70309-7.
Full textLequin, Mathilde. "Comment nommer la lignée humaine ? De l’ordre des Bimanes à la sous-tribu des hominiens." Revue d'histoire des sciences Tome 75, no. 1 (June 1, 2022): 35–69. http://dx.doi.org/10.3917/rhs.751.0035.
Full textNahon, JL. "Des gènes "chimères" sont apparus dans la lignée des hominidés : l'indice d'une spécificité génomique humaine ?" médecine/sciences 17, no. 3 (2001): 407. http://dx.doi.org/10.4267/10608/1938.
Full textSchaad, Gabrielle. "L’Homme ordinaire. Travail, loisirs et société automatisée dans l’installation photographique de Okamoto Tarō, Osaka, 1970." Transbordeur 2 (2018): 114–23. http://dx.doi.org/10.4000/12gwt.
Full textDissertations / Theses on the topic "Lignée humaine"
Korpal, Yannick. "L'os sphénoïde dans la lignée humaine." Paris, Muséum national d'histoire naturelle, 2005. http://www.theses.fr/2005MNHN0065.
Full textThe sphenoid is the central bone of the human skull. Forming the skull base bone complex with the ethmoid and the basi-occipital part, this sphenoid bone is associated with the skull vault bones, the face complex and indirectly with the vertebral column. Our method is based on the use of radiographs for 107 Homo sapiens, 27 Pan and Gorilla, in addition with 23 fossil hominids, Paranthropus, Australopithecus, Homo erectus and Homo neanderthalensis. Classical measures as length and angulations are completed by a new model for the inner profile of the endocranium, witch is called the “ellipses method”. It’s using coronal, transverse and sagittal radiographs of the skull. The statistical analyse that follows gives us a new point of view upon the classical skull base flexion. This flexion is a characteristic of the human lineage. In Homo sapiens the skull base is completely bent in the occipital bascule movement. Compared with the African Apes, and using the Principal Component Analyses, this flexion could be split into five major processes. The main is the spheno-occipital flexion. This is linked with a pharyngeal flexion, accompanied by an enlargement of the sphenoidal facial area and a dorsal expansion. The vault is seen in hydrostatic balance with the Sphenoid by the way of the “ellipses method”. Then we can see that the vertical gain is given by the Sphenoid bone to the entire skull base, thus to the postural disposition of the axial skeleton. Four modes can be separated for distinction in the rotation mode. It could be useful to discover a fossil ape to complete this approach
Poulain, Marine. "Développement de la lignée germinale femelle humaine." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T056/document.
Full textWoman fertility is partially dictated by the set up of the human female germ line. During the last ten years, which saw an increased number of couples consulting for assisted reproductive cares, the hypothesis of an early alteration in reproduction functions has emerged.In the fetal ovary, germ cells enter the path of oogenesis differentiation characterized by meiotic initiation. On this subject, vast majority of the scientific data are obtained from the mouse model, even if differences with human ovarian physiology are widely acknowledged. Therefore it is necessary to extend our knowledge on human ovarian development and identify its perturbations. The objective of my work was to assess a new model to study ovarian growth, studying regulation of meiotic entry and perturbation of germ line differentiation.We sat up a new xenograft model of early human fetal ovaries, when very early meiotic germ cells appear. Organ growth and germ cells differentiation were comparable with in vivo observations. Using this model with an RNA-interference strategy, we inhibited the expression of an oogonia germ cell gene, DMRTA2. This inhibition conducted to a significantly reduced number of germ cells gene that initiated meiosis and DMRTA2 seemed to be required for mitotic-meiotic transition. In another hand, we identified, in the ovary, the expression of germ cells markers described as specifically male in rodent (PLZF, DNMT3L, FGF9, NANOS2 ou CYP26B1). The expression of these markers in the human ovary could explain the observation of mitotic germ cells in late fetal ovaries (30 wpf).In parallel, we tested germ cells sensibility to a synthetic glucocorticoid, dexamethasone, administrated during pregnancy in some justified pathologies. We observed an increased expression of PLZF that could explain the decreased number of germ cells observed in treated ovaries.In conclusion, we identified a new gene expressed in human fetal ovaries, potentially involved in the meiotic entry, and we extended our knowledge to characterized human germ line development. However, many points have to be clarified, as the possible competence of late mitotic germ cells to form oocytes
Vanderhaeghen, Pierre. "Caractérisation de gênes de récepteurs olfactifs exprimés dans la lignée mâle des mammifères." Doctoral thesis, Universite Libre de Bruxelles, 1996. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/212307.
Full textAugoyard, Mathilde. "Covariation des tissus osseux et dentaires chez les humains modernes et tendances évolutives dans la lignée humaine." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0480.
Full textCortical bone and dentine are two biological tissues sharing a common genetic origin, overall structure, composition, and embryological development, distinct from those of enamel. Various observations suggest the possibility of coordinated postnatal development of these two tissues in hominins. For example, Neandertals display higher cortical bone volumes in their infra-cranial skeleton and greater dentine robustness compared to modern humans, while absolute enamel volumes are similar between the two taxa. Studies of immature Neandertal specimens indicate that their cortical bone and dentine robustness may be present from early developmental stages. In this doctoral research, we aimed to understand whether the structural and developmental affinities between cortical bone and dentine could lead to coordinated postnatal development of these tissues in modern humans. To this end, we measured the coordinated variation of cortical bone and dentine volumes in a sample of modern humans, comprising 12 immature individuals and 70 adults. Using microtomographic acquisitions of the arm, forearm bones, and anterior dentition, we conducted a methodological approach combining the quantification of cortical bone and dentine volumes with the analysis of their topographic distribution. Our results highlight a developmental desynchronization between cortical bone and dentine during the growth of immature individuals, leading to weak covariation between their cortical bone and dentine volumes. The bone-dentine covariation signal is stronger in adults, suggesting that common factors may influence postnatal development of these tissues once skeletal and dental maturation is achieved. This research highlights the predominant role of the hormonal milieu in the postnatal development of these tissues, while the biomechanical history of the skeleton appears to have a more limited impact. A preliminary analysis of bone-dentine covariation was conducted on chimeric individuals of Paranthropus, Australopithecus, and Neandertals. Most of these individuals deviate from the modern human bone-dentine relationship, characterized by higher dentine volumes in fossil taxa and cortical bone volumes similar to those of modern humans. A slowdown in growth and development has been described in Homo sapiens compared to fossil hominins, which may explain the unique bone-dentine relationship seen in this taxon. This doctoral thesis provides an original contribution to the study of bone and dental tissue volumes and distribution in various fossil and extant hominin taxa, offering insights into the impact of genetic, environmental, and evolutionary factors acting on their development
Bonafoux, Béatrice. "Le transcriptome du réticulocyte : marqueurs moléculaires de la lignée érythroïde, intérêt en biologie humaine." Montpellier 1, 2005. http://www.theses.fr/2005MON1T028.
Full textPeltier, Lucas. "Impact d’une exposition au fer sur l’axe S1P/S1PR dans la lignée ostéoblastique humaine MG-63." Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1B059/document.
Full textOsteoporosis may complicate genetic or secondary iron overload as reported in clinical and animal studies. However, the mechanisms leading to disrupted bone homeostasis are still to be fully elucidated. In vitro, iron exposure of both osteoblast and osteoclast cell models induces phenotypic and functional impairment, but the molecular mechanisms of iron excess on bone cell physiology are not well characterized, particularly in osteoblast. Our objective was to study the impact of iron overload on osteoblast biology and characterize the molecular mechanisms involved. Transcriptomic analysis previously performed by our group on MG-63 osteoblast-like cell-line to identify iron-modulated genes revealed that expression of SPNS2 gene, which encodes a transporter for the signaling lipid sphingosine 1-phosphate (S1P), is potentially induced by iron. The purpose of this work was to characterize the SPNS2 iron-related regulation and analyze its potential impact on S1P efflux and the S1P/S1PR signaling pathway in MG-63 cells. Our findings showed that iron exposure induces a dose-dependent increase of SPNS2 mRNA levels in MG-63 osteoblast-like cells that was not observed in hepatocyte and enterocyte cell models. We then performed a fluxomic assay on MG-63 cells to investigate iron potential impact on S1P efflux. Unexpectedly, our data showed that extracellular S1P levels were decreased in presence of iron excess and its associated SPNS2 upregulation. Furthermore, based on the observed iron associated S1PR1 and COL1A1 decrease, the defect in S1P export system seems to have functional consequence on MG-63 cells. These results suggest that iron may affect osteoblast S1P/SPR signaling and potentially alter a wide range of bone processes, thus participating in bone impairment in situations of chronic iron overload. These data open a new door for the understanding of mechanisms involved in iron-induced osteoporosis
Velez, Laurent. "Culture de Toxoplasma Gondii sur la lignée cellulaire monocytaire humaine THP1 : application à l'évaluation d'agents anti parasitaires." Bordeaux 2, 1993. http://www.theses.fr/1993BOR23010.
Full textValentin-Séverin, Isabelle. "Evaluation de la toxicité et de la génotoxicité à l'aide d'une lignée cellulaire hépatique d'origine humaine "HepG2"." Dijon, 2002. http://www.theses.fr/2002DIJOS017.
Full textLe, Fevre Anne-Céline. "Caractérisation des signatures moléculaires d'une lignée cellulaire humaine exposée à différents anticancéreux par l'étude des profils d'expression génique." Paris 11, 2006. http://www.theses.fr/2006PA11T055.
Full textGuise-Honoré, Stéphanie. "Implication de la protéine Tau dans l'apoptose induite par les agents anticancéreux sur une lignée humaine de neuroblastome." Aix-Marseille 2, 2000. http://theses.univ-amu.fr.lama.univ-amu.fr/PHA_2000_1540.pdf.
Full textBooks on the topic "Lignée humaine"
(Canada), Medical Research Council, ed. Lignes directrices concernant la recherche sur des sujets humains. 2nd ed. Ottawa: Conseil de recherches médicales du Canada, 1987.
Find full textLebec, Solange. Analyse chromosomique et des glycoconjugués de lignées cellulaires de mélanocytes malins humains. Grenoble: A.N R.T. Université Pierre Mendès France Grenoble 2, 1986.
Find full textCanada. Programme des produits thérapeutiques., ed. Ligne directrice à l'intention de l'industrie: Évaluation de la sécurité virologique des produits issus de la biotechnologie et dérivés de lignées cellulaires d'origine humaine ou animale, ICH thème Q5A. Ottawa, Ont: Programme des produits thérapeutiques, Santé Canada, 2000.
Find full textAgrikoliansky, Eric. La Ligue française des droits de l'homme et du citoyen depuis 1945: Sociologie d'un engagement civique. Paris: L'Harmattan, 2002.
Find full textAgrikoliansky, Eric. La ligue française des droits de l'homme et du citoyen depuis 1945: Sociologie d'un engagement civique. Paris: Harmattan, 2002.
Find full textStiftung zur Förderung der Archäologie im rheinischen Braunkohlenrevier. Kolloquium, ed. Schatzkammer rheinisches Braunkohlenrevier: Geschichten aus der Vergangenheit. Mainz: Verlag P. von Zabern, 2010.
Find full textNaquet, Emmanuel. Pour l'humanité: La Ligue des droits de l'homme, de l'affaire Dreyfus à la défaite de 1940. Rennes: Presses universitaires de Rennes, 2014.
Find full textAufleger, Michaela. Braunkohlenarchäologie im Rheinland: Entwicklung von Kultur, Umwelt und Landschaft : Kolloquium der Stiftung zur Förderung der Archäologie im rheinischen Braunkohlenrevier in Brauweiler vom 5.-6. Oktober 2006. Edited by LVR-Amt für Bodendenkmalpflege im Rheinland and Stiftung zur Förderung der Archäologie im rheinischen Braunkohlenrevier. Kolloquium. Weilerswist: Verlag Ralf Liebe, 2010.
Find full textPierre, Michel. La Ligue des droits de l'homme en Anjou: Un siècle de combats civiques. [Angou?]: Ligue des droits de l'homme, 1998.
Find full textValin, Claudy. La Ligue des droits de l'homme en Charente-Maritime: Des origines à nos jours. Saint-Jean-d'Angély [France]: Bordessoules, 1988.
Find full textBook chapters on the topic "Lignée humaine"
Becker, Sören, and Matthias Naumann. "From Lignite Regions to Transition Labs: Rethinking Regional Politics of Lignite from the Perspective of the “Politics of Scale”." In Rescaling Sustainability Transitions, 223–45. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-69918-4_10.
Full textMoinuddin, Syed G. A., John R. Cort, Clyde A. Smith, Christophe Hano, Laurence B. Davin, and Norman G. Lewis. "Linum Lignan and Associated Biochemical Pathways in Human Health and Plant Defense." In Genetics and Genomics of Linum, 167–93. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-23964-0_11.
Full textHuntley, Brian John. "The Ecological Role of Fire." In Ecology of Angola, 149–65. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-18923-4_7.
Full textConsolandi, Clarissa. "High-Throughput Multiplex HLA-Typing by Ligase Detection Reaction (LDR) and Universal Array (UA) Approach." In DNA and RNA Profiling in Human Blood, 115–27. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-553-4_9.
Full textCox, Eric, Ijeoma Uzoma, Catherine Guzzo, Jun Seop Jeong, Michael Matunis, Seth Blackshaw, and Heng Zhu. "Identification of SUMO E3 Ligase-Specific Substrates Using the HuProt Human Proteome Microarray." In Methods in Molecular Biology, 455–63. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2550-6_32.
Full textRashid, Ishtiaque, Miaw-Sheue Tsai, Aleksandr Sverzhinsky, Aye Su Hlaing, Brian Shih, Aye C. Thwin, Judy G. Lin, Su S. Maw, John M. Pascal, and Alan E. Tomkinson. "Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect Cells." In Methods in Molecular Biology, 243–69. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2063-2_15.
Full textClavel, Thomas, and Job O. Mapesa. "Phenolics in Human Nutrition: Importance of the Intestinal Microbiome for Isoflavone and Lignan Bioavailability." In Natural Products, 2433–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-22144-6_94.
Full textRamachandran, R. "Effect of Human Resource Practices on Employees' Behavioral Outcome in Neyveli Lignite Corporation (NlC) India Ltd, Neyveli." In Handbook of Evidence Based Management Practices in Business, 228–36. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003415725-30.
Full textMezzina, Mauro, Silvano Nocentini, Jeannette Nardelli, A. Ivana Scovassi, Umberto Bertazzoni, and Alain Sarasin. "DNA Ligase Activity in Human Cells from Normal Donors and from Patients with Bloom’s Syndrome and Fanconi’s Anemia." In DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells, 461–69. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-1327-4_37.
Full textSenut, Brigitte. "Qui est le premier représentant de la lignée humaine ?" In Une belle histoire de l'Homme, 113–16. Flammarion, 2017. http://dx.doi.org/10.3917/flam.heyer.2017.01.0113.
Full textConference papers on the topic "Lignée humaine"
Dubuc, A., P. Monsarrat, S. Laurencin-Dalicieux, F. Virard, J. P. Sarrette, N. Merbahi, and S. Cousty. "Application du plasma atmosphérique froid en oncologie : une revue systématique." In 66ème Congrès de la SFCO. Les Ulis, France: EDP Sciences, 2020. http://dx.doi.org/10.1051/sfco/20206603018.
Full textMARCUZ, C., C. A. MOURÃO, and S. M. A. BUENO. "ADSORÇÃO DE IgG HUMANA EM CRIOGEL DE POLIACRILAMIDA COM LIGANTE PSEUDOBIOESPECÍFICO IMOBILIZADO." In XXII Congresso Brasileiro de Engenharia Química. São Paulo: Editora Blucher, 2018. http://dx.doi.org/10.5151/cobeq2018-co.137.
Full textFefilova, E. A., and O. Yu Shuvalov. "THE EFFECT OF MDM2 UBIQUITIN LIGASE ON ENERGY METABOLISM ENZYMES IN CELL MODELS OF HUMAN NON-SMALL CELL LUNG CANCER." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-380.
Full textPERNA, Valerio. "Unveiling the Post-Digital Paradigm Cultural Implications in a Post-Hu- man Design Ecology." In ISSUES OF HOUSING, PLANNING, AND RESILIENT DEVELOPMENT OF THE TERRITORY Towards Euro-Mediterranean Perspectives. POLIS PRESS, 2023. http://dx.doi.org/10.37199/c41000114.
Full textHaraguchi, Soichi, Tina Pastoor, William Guy Bradley, and Akiko Tanaka. "Abstract B29: Improving the efficacy of dendritic cell-based human papillomavirus vaccines in mice using a natural lignin-carbohydrate complex and/or synthetic lignin-like polyphenol polymers." In Abstracts: AACR Special Conference: Tumor Immunology and Immunotherapy: A New Chapter; December 1-4, 2014; Orlando, FL. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/2326-6074.tumimm14-b29.
Full textAlabdullah, M., R. Ali, P. Moseley, S. Chan, E. Rakha, and S. Madhusudan. "PO-236 Human ligase profiling to predict platinum sensitivity and clinical outcome in primary epithelial ovarian cancers." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.752.
Full textUrban, Zena M., Lauren van Reesema, Minglei Bian, Thomas C. Smyrk, Gloria Peterson, and Amy H. Tang. "Abstract 4442: Inhibition of SIAH E3 ligase function leads to increased cell death in metastatic human cancer cells." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4442.
Full textSteklov, Mikhail, Silvia Pandolfi, Maria Francesca Baietti, Paolo Carai, Mingzhen Zhang, Hyunbum Jang, Yanyan Cai, et al. "Abstract A14: Mutations in the ubiquitin ligase adaptor LZTR1 drive human disease by dysregulating RAS ubiquitination and signaling." In Abstracts: AACR Special Conference on Targeting RAS-Driven Cancers; December 9-12, 2018; San Diego, CA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1557-3125.ras18-a14.
Full textNjogu, Monicah M., Ming Lei Bian, Jamie Eisner, and Amy H. Tang. "Abstract 2008: Proteomic analysis of SIAH2 E3 ligase complex in oncogenic K-Ras-driven cell transformation in human cancer." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2008.
Full textChristofidou-Solomidou, Melpo, Ralph Pietrofesa, and Steven Albelda. "Novel Synthetic lignan reduces asbestos-induced damage in human pleural mesothelial cells-Potential clinical usefulness in inhibiting pleural malignant mesothelioma." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa1581.
Full textReports on the topic "Lignée humaine"
Langlais, Pierre-Carl. Transparence de la recherche. Comité pour la science ouverte, 2024. https://doi.org/10.52949/62.
Full textLignes directrices internationales d'éthique pour la recherche en matière de santé impliquant des participants humains. Council for International Organizations of Medical Sciences (CIOMS), 2016. http://dx.doi.org/10.56759/fyee7010.
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