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1

Bellelli, Andrea, and Jannette Carey. Reversible Ligand Binding. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119238508.

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2

Khan, Masood N., and John W. A. Findlay, eds. Ligand-Binding Assays. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2009. http://dx.doi.org/10.1002/9780470541517.

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3

H, Sawyer William, ed. Quantitative characterization of ligand binding. New York: Wiley-Liss, 1995.

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4

Stoddard, Barry L., ed. Computational Design of Ligand Binding Proteins. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3569-7.

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5

Protein-ligand interactions: Methods and applications. 2nd ed. New York: Humana Press, 2013.

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6

Krishna, Mallia A., and Smith Paul K, eds. Immobilized affinity ligand techniques. San Diego: Academic Press, 1992.

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7

Podjarny, Alberto, Annick P. Dejaegere, and Bruno Kieffer, eds. Biophysical Approaches Determining Ligand Binding to Biomolecular Targets. Cambridge: Royal Society of Chemistry, 2011. http://dx.doi.org/10.1039/9781849732666.

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8

E, Harding S., and Chowdhry Babur Z, eds. Protein-ligand interactions, structure and spectroscopy: A practical approach. Oxford: Oxford University Press, 2001.

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9

Wyman, Jeffries. Binding and linkage: Functional chemistry of biological macromolecules. Mill Valley, Calif: University Science Books, 1990.

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10

Ligand-receptor energetics: A guide for the perplexed. New York: Wiley, 1997.

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11

Munson, Peter J. A user's guide to LIGAND: Data analysis and curve-fitting for ligand binding experiments. 2nd ed. Bethesda, Md: Laboratory of Theoretical and Physical Biology, National Institute of Child Health and Human Development, National Institutes of Health, 1987.

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12

1961-, Keen Mary, ed. Receptor binding techniques. Totowa, N.J: Humana Press, 1999.

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13

Ulrich, Nienhaus G., ed. Protein-ligand interactions: Methods and applications. Totowa, N.J: Humana Press, 2005.

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14

Matejtschuk, Paul. Structure and ligand-binding properties of abnormal human albumins. [s.l.]: typescript, 1986.

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15

Woodbury, Charles P. Introduction to macromolecular binding equilibria. Boca Raton: CRC Press, 2008.

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16

Roterman-Konieczna, Irena, ed. Identification of Ligand Binding Site and Protein-Protein Interaction Area. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-5285-6.

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17

P, Davenport Anthony, ed. Receptor binding techniques. 2nd ed. Totowa, N.J: Humana Press, 2005.

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18

Receptor binding techniques. 3rd ed. New York, NY: Humana Press, 2012.

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19

Thermodynamic theory of site-specific binding processes in biological macromolecules. Cambridge, [Eng.]: Cambridge University Press, 1995.

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20

N, Khan Masood, and Findlay John W. A, eds. Ligand-binding assays: Development, validation, and implementation in the drug development arena. Hoboken, N.J: Wiley, 2010.

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21

(Firm), Knovel, ed. Engineering biosensors: Kinetics and design applications. San Diego: Academic Press, 2002.

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22

NATO ASI/FEBS Course on DNA-Ligand Interactions: From Drugs to Proteins (1986 Abbey of Fontevraud). DNA-ligand interactions: From drugs to proteins. New York: Plenum Press, 1987.

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23

Hans-Joachim, Böhm, and Gubernator Klaus, eds. Structure-based ligand design. Weinheim: Wiley-VCH, 1998.

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24

1942-, Berthon Guy, ed. Handbook of metal-ligand interactions in biological fluids. New York: Marcel Dekker, 1995.

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25

Hans-Joachim, Böhm, and Schneider Gisbert 1965-, eds. Protein-ligand interactions from molecular recognition to drug design. Weinheim: Wiley-VCH, 2003.

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26

Kozik, Andrzej. Thiamine-protein interaction: Chemical mechanism of ligand-binding and bioanalytical application of thiamine-binding proteins from seeds. Kraków: Nakł. Uniwersytetu Jagiellońskiego, 1996.

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27

Calderwood, David Alexander. An investigation of the role of integrin A-domains in ligand binding. Manchester: University of Manchester, 1996.

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28

N, Khan Masood, and Findlay John W. A, eds. Ligand-binding assays: Development, validation, and implementation in the drug development arena. Hoboken, N.J: Wiley, 2009.

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29

Ligand-macromolecular interactions in drug discovery: Methods and protocols. New York: Springer, 2009.

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30

Nualláin, Brian Ó. An investigation of ligand interactions with apoflavodoxin from Desulfovibrio vulgaris and the cell adhesion molecule LFA-3. Dublin: University College Dublin, 1998.

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31

Bellelli, Andrea, and Jannette Carey. Reversible Ligand Binding: Theory and Experiment. Wiley & Sons, Limited, John, 2017.

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32

Computational Design of Ligand Binding Proteins. Humana, 2018.

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33

Bellelli, Andrea, and Jannette Carey. Reversible Ligand Binding: Theory and Experiment. Wiley & Sons, Incorporated, John, 2017.

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34

Stoddard, Barry L. Computational Design of Ligand Binding Proteins. Springer New York, 2016.

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35

Bellelli, Andrea, and Jannette Carey. Reversible Ligand Binding: Theory and Experiment. Wiley & Sons, Incorporated, John, 2017.

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36

Bellelli, Andrea, and Jannette Carey. Reversible Ligand Binding: Theory and Experiment. Wiley & Sons, Limited, John, 2017.

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37

Folkers, Gerd, Raimund Mannhold, Hugo Kubinyi, and Holger Gohlke. Protein-Ligand Interactions. Wiley & Sons, Limited, John, 2012.

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38

Folkers, Gerd, Raimund Mannhold, Hugo Kubinyi, and Holger Gohlke. Protein-Ligand Interactions. Wiley & Sons, Incorporated, John, 2012.

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39

Folkers, Gerd, Raimund Mannhold, Hugo Kubinyi, and Holger Gohlke. Protein-Ligand Interactions. Wiley & Sons, Incorporated, John, 2012.

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40

Folkers, Gerd, Raimund Mannhold, Hugo Kubinyi, and Holger Gohlke. Protein-Ligand Interactions. Wiley & Sons, Incorporated, John, 2012.

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41

Gerhard Müller, Gerd Folkers, Raimund Mannhold, Beat Ernst, and Hugo Kubinyi. Ligand Binding: Diversity of Modes and Functions. Wiley & Sons, Limited, John, 2016.

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42

Protein-Ligand Interactions: Methods and Applications. Springer, 2021.

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43

Williams, Mark A., and Tina Daviter. Protein-Ligand Interactions: Methods and Applications. Humana Press, 2016.

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44

McLaughlin, Stephen H., Mark A. Williams, Christopher M. Johnson, and Tina Daviter. Protein-Ligand Interactions: Methods and Applications. Springer, 2021.

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45

Ren, Ke, and Ronald Dubner. The first crystal structure of an ionotropic glutamate receptor ligand-binding core. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0032.

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Abstract:
The known functional ionotropic glutamate receptors (iGluRs) are composed of three major subtypes: AMPA, NMDA, and kainate. In 1998, in the landmark paper discussed in this chapter, Armstrong et al. provided the first crystal structure of an iGluR-subunit ligand-binding core, the S1S2 region of the rat GluA2 ‘flop’ isoform. They solved its structure with X-ray crystallography from selenomethonine crystals. They also identified residues involved in kainate binding, analysed allosteric sites that regulate affinity and specificity of the agonist, and mapped potential subunit–subunit interaction sites. They also proposed that binding of different agonists may result in variable degrees of domain closure. This work has profound impact on the field and it has been importantly cited. Subsequently, numerous high-resolution crystal structures of ligand-binding domains of iGluRs in complex with ligands, both agonists and antagonists, have been solved.
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46

DNA-ligand interactions. Plenum published in cooperation with NATO Scientific Affairs Division, 1987.

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47

Mallia, A. Krishna. Immobilized Affinity Ligand Techniques. Elsevier Science & Technology Books, 2012.

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48

Filfil, Rana. Volumetric characterizations of protein denaturation and ligand binding. 2000.

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49

Metal ion solvation and metal-ligand interactions. Amsterdam: Elsevier Science, 2001.

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50

Davenport, Anthony P. Receptor Binding Techniques. 2nd ed. Humana Press, 2005.

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