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Journal articles on the topic 'Lhops'

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Author: Grafiati
Published: 18 May 2024

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1

Nakamura, Shingo, Naoko Ando, Masayuki Ishihara, and Masahiro Sato. "Development of Novel Heparin/Protamine Nanoparticles Useful for Delivery of Exogenous Proteins In Vitro and In Vivo." Nanomaterials 10, no. 8 (August 12, 2020): 1584. http://dx.doi.org/10.3390/nano10081584.

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We previously reported that heparin/protamine particles (LHPPs) produced as nanoparticles through simple mixing of raw materials exhibit sustained protein release and can be retained in cells. In the present study, we modified LHPPs without employing any organic synthetic approach. The resulting LHPPs were re-named as improved LHPPs (i-LHPPs) and have the ability to retain cell-penetrating peptides (GRKKRRQRRRPPQ) based on electrostatic interactions. We examined whether i-LHPPs can introduce exogenous proteins (i.e., lacZ protein encoding bacterial β-galactosidase) into cultured cells in vitro, or into murine hepatocytes in vivo through intravenous injection to anesthetized mice. We found an accumulation of the transferred protein in both in vitro cultured cells and in vivo hepatocytes. To the best of our knowledge, reports of successful in vivo delivery to hepatocytes are rare. The i-LHPP-based protein delivery technique will be useful for in vivo functional genetic modification of mouse hepatocytes using Cas9 protein-mediated genome editing targeting specific genes, leading to the creation of hepatic disease animal models for research that aims to treat liver diseases.
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2

Kurihara, Hideyuki, Kenta Yachiyama, and Chihiro Morimoto. "Classification of Marine Algae–Derived Compounds by the Mechanism Responsible for Decreasing Lipoxygenase-Catalyzed Lipid Hydroperoxides." Natural Product Communications 17, no. 8 (August 2022): 1934578X2211152. http://dx.doi.org/10.1177/1934578x221115249.

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Lipoxygenase (LOX)-mediated lipid hydroperoxides (LHPOs) are converted to physiologically active mediators. Thus, decreasing hydroperoxides is important for diminishing various health-related risks. In this study, decreasing compounds of LOX-catalyzed LHPOs were investigated and classified by mechanism using a modified triple LOX-indamine dye formation (IDF) method. The compounds 2,3-dibromo-4,5-dihydroxybenzyl methyl ether (1) and fucoxanthin (2) were isolated from algae as compounds that can decrease hydroperoxides. Along with previously isolated pheophytin a (3), a chlorophyll-related compound, and purchased nordihydroguaiaretic acid (4), a well-known lipoxygenase inhibitor, all the compounds were examined to determine the mechanisms responsible for decreasing LHPOs by using a modified triple LOX-IDF method. Compounds 1 and 4 were found to be LOX inhibitors, compound 2 was a decomposer of the produced LHPOs, and compound 3 was both an inhibitor and a decomposer of the produced LHPOs.
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3

Santos, Paulo H. D., Edson Bazzo, Susanne Becker, Rudi Kulenovic, and Rainer Mertz. "Development of LHPs with ceramic wick." Applied Thermal Engineering 30, no. 13 (September 2010): 1784–89. http://dx.doi.org/10.1016/j.applthermaleng.2010.04.010.

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4

Raftis, Jennifer, Andrew Lucking, Amanda Hunter, Mike Millar, Mike Fitzpatrick, Giora Feuerstein, David Newby, and Nikhil Joshi. "Lyophilised reconstituted human platelets increase thrombus formation in a clinical ex vivo model of deep arterial injury." Thrombosis and Haemostasis 108, no. 07 (2012): 176–82. http://dx.doi.org/10.1160/th12-02-0059.

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SummaryPlatelets are the principal component of the innate haemostatic system that protect from traumatic bleeding. We investigated whether lyophilised human platelets (LHPs) could enhance clot formation within platelet-free and whole blood environments using an ex vivo model of deep arterial injury. Lyophilised human platelets were produced from stored human platelets and characterised using conventional, fluorescent and electron microscopic techniques. LHPs were resuspended in platelet-free plasma (PFP) obtained from citrated whole human blood to form final concentrations of 0,20 and 200 × 109 LHPs/L. LHPs with recalcified PFP or whole blood were perfused through the chamber at low (212 s-1) and high (1,690 s-1) shear rates with porcine aortic tunica media as thrombogenic substrate. LHPs shared morphological characteristics with native human platelets and were incorporated into clot generated from PFP or whole blood. Histomorphometrically measured mean thrombus area increased in a dose-dependent manner following the addition of LHPs to PFP under conditions of high shear [704 μm2 ± 186 μm2 (mean ± SEM), 1,511 μm2 ± 320 μm2 and 2,378 μm2 ± 315 μm2, for LHPs at 0, 20 and 200 × 109 /l, respectively (p= 0.012)]. Lyophil-ised human platelets retain haemostatic properties when reconstituted in both PFP and whole blood, and enhance thrombus formation in a model of deep arterial injury. These data suggest that LHPs have the potential to serve as a therapeutic intervention during haemorrhage under circumstances of trauma, and platelet depletion or dysfunction.
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5

Xu, Mengjia, Zhi Li, Xiaogan Zhao, and Wei Li. "Prebiotic Properties of Exopolysaccharides from Lactobacillus helveticus LZ-R-5 and L. pentosus LZ-R-17 Evaluated by In Vitro Simulated Digestion and Fermentation." Foods 11, no. 16 (August 18, 2022): 2501. http://dx.doi.org/10.3390/foods11162501.

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The in vitro digestion and fermentation behaviors of Lactobacillus helveticus LZ-R-5- and L. pentosus LZ-R-17-sourced exopolysaccharides (LHEPS and LPEPS) were investigated by stimulated batch-culture fermentation system. The results illustrated that LHEPS was resistant to simulated saliva and gastrointestinal (GSI) digestion, whereas LPEPS generated a few monosaccharides after digestion without significant influence on its main structure. Additionally, LHEPS and LPEPS could be consumed by the human gut microbiota and presented stronger bifidogenic effect comparing to α-glucan and β-glucan, as they promote the proliferation of Lactobacillus and Bifidobacterium in cultures and exhibited high values of selectivity index (13.88 and 11.78, respectively). Furthermore, LPEPS achieved higher contents of lactic acid and acetic acid (35.74 mM and 45.91 mM, respectively) than LHEPS (35.20 mM and 44.65 mM, respectively) during fermentation for 48 h, thus also resulting in a larger amount of total SCFAs (110.86 mM). These results have clearly indicated the potential prebiotic property of EPS fractions from L. helveticus LZ-R-5 and L. pentosus LZ-R-17, which could be further developed as new functional food prebiotics to beneficially improve human gut health.
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6

Tutantsev, Andrei S., Ekaterina I. Marchenko, Natalia N. Udalova, Sergey A. Fateev, Eugene A. Goodilin, and Alexey B. Tarasov. "Structural Disorder in Layered Hybrid Halide Perovskites: Types of Stacking Faults, Influence on Optical Properties and Their Suppression by Crystallization Engineering." Nanomaterials 11, no. 12 (December 8, 2021): 3333. http://dx.doi.org/10.3390/nano11123333.

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Layered hybrid halide perovskites (LHHPs) are an emerging type of semiconductor with a set of unique optoelectronic properties. However, the solution processing of high-quality LHHPs films with desired optical properties and phase composition is a challenging task, possibly due to the structural disorder in the LHHP phase. Nevertheless, there is still a lack of experimental evidence and understanding of the nature of the structural disorder in LHHPs and its influence on the optical properties of the material. In the current work, using 2D perovskites (C4H9NH3)2(CH3NH3)n−1PbnI3n+1 (further BA2MAn−1PbnI3n+1) with n = 1–4 as a model system, we demonstrate that deviations in LHHPs optical properties and X-ray diffraction occur due to the presence of continuous defects—Stacking Faults (SFs). Upon analyzing the experimental data and modeled XRD patterns of a possible set of stacking faults (SFs) in the BA2MAPb2I7 phase, we uncover the most plausible type of SFs, featured by the thickness variation within one perovskite slab. We also demonstrate the successful suppression of SFs formation by simple addition of BAI excess into BA2MAn−1PbnI3n+1 solutions.
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7

Wang, Peng, Fu-Cheng Liang, Daniel Wittmann, Alex Siegel, Shu-ou Shan, and Bernhard Grimm. "Chloroplast SRP43 acts as a chaperone for glutamyl-tRNA reductase, the rate-limiting enzyme in tetrapyrrole biosynthesis." Proceedings of the National Academy of Sciences 115, no. 15 (March 26, 2018): E3588—E3596. http://dx.doi.org/10.1073/pnas.1719645115.

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Assembly of light-harvesting complexes requires synchronization of chlorophyll (Chl) biosynthesis with biogenesis of light-harvesting Chl a/b-binding proteins (LHCPs). The chloroplast signal recognition particle (cpSRP) pathway is responsible for transport of nucleus-encoded LHCPs in the stroma of the plastid and their integration into the thylakoid membranes. Correct folding and assembly of LHCPs require the incorporation of Chls, whose biosynthesis must therefore be precisely coordinated with membrane insertion of LHCPs. How the spatiotemporal coordination between the cpSRP machinery and Chl biosynthesis is achieved is poorly understood. In this work, we demonstrate a direct interaction between cpSRP43, the chaperone that mediates LHCP targeting and insertion, and glutamyl-tRNA reductase (GluTR), a rate-limiting enzyme in tetrapyrrole biosynthesis. Concurrent deficiency for cpSRP43 and the GluTR-binding protein (GBP) additively reduces GluTR levels, indicating that cpSRP43 and GBP act nonredundantly to stabilize GluTR. The substrate-binding domain of cpSRP43 binds to the N-terminal region of GluTR, which harbors aggregation-prone motifs, and the chaperone activity of cpSRP43 efficiently prevents aggregation of these regions. Our work thus reveals a function of cpSRP43 in Chl biosynthesis and suggests a striking mechanism for posttranslational coordination of LHCP insertion with Chl biosynthesis.
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8

Lee, Jih-Jong, Albert Taiching Liao, and Shang-Lin Wang. "L-Asparaginase, Doxorubicin, Vincristine, and Prednisolone (LHOP) Chemotherapy as a First-Line Treatment for Dogs with Multicentric Lymphoma." Animals 11, no. 8 (July 26, 2021): 2199. http://dx.doi.org/10.3390/ani11082199.

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Cyclophosphamide exhibits the weakest therapeutic effect compared with vincristine and doxorubicin in the CHOP (C, cyclophosphamide; H, doxorubicin; O, vincristine; and P, prednisolone) chemotherapeutic protocol for the treatment of canine lymphoma. Twenty dogs with multicentric lymphoma were treated using the LHOP protocol, which used l-asparaginase in place of cyclophosphamide, and the outcomes were historically compared with those of dogs that received CHOP chemotherapy in the same institution. No significant differences were found in age (p = 0.107), body weight (p = 0.051), sex (p = 0.453), clinical stage V (p = 1), substage b (p = 0.573), T-cell phenotype (p = 0.340), overall response (p = 1), and hypercalcaemia status (p = 1) between the LHOP and CHOP groups. The adverse effects of l-asparaginase were well tolerated and self-limiting. The median PFS (progression-free survival) and median ST (survival time) in the LHOP group were 344 days (range: 28–940 days) and 344 days (range: 70–940 days), respectively. The median PFS and median ST in the CHOP group were 234 days (range: 49–1822 days) and 314 days (range: 50–1822 days), respectively. The dogs that received LHOP chemotherapy had a significantly longer PFS than the dogs that received CHOP chemotherapy (p = 0.001). No significant difference was observed in ST between the LHOP and CHOP groups (p = 0.131). Our study findings thus indicate that the LHOP protocol can be used as a first-line chemotherapeutic protocol in canine multicentric lymphoma.
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9

Li, Yinsheng, Jing Yang, Jinxiang Chen, and Jian Yin. "Study of the Heat Transfer Performance of Laminated Paper Honeycomb Panels." Biomimetics 8, no. 1 (January 19, 2023): 46. http://dx.doi.org/10.3390/biomimetics8010046.

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To apply functional honeycomb panels (FHPs) in actual engineering projects, the heat transfer performance and intrinsic heat transfer mechanism of laminated honeycomb panels (LHPs, total thickness of 60 mm) with different structural parameters were investigated in this study by a heat flow meter. The results showed that (1) the equivalent thermal conductivity λequ of the LHP was almost independent of the cell size, when it consisted of a small single-layer thickness. Thus, LHP panels with a single-layer thickness of 15–20 mm are recommended. (2) A heat transfer model of LHPs was developed, and it was concluded that the heat transfer performance of LHPs depends greatly on the performance of their honeycomb core. Then, an equation was derived for the steady state temperature distribution of the honeycomb core. (3) The contribution of each heat transfer method to the total heat flux of the LHP was calculated using the theoretical equation. According to the theoretical results, the intrinsic heat transfer mechanism affecting the heat transfer performance of LHPs was revealed. The results of this study laid the foundation for the application of LHPs in building envelopes.
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10

Ortíz García, Edna Z., and Andrés F. Gualdrón Reyes. "Safe or risk? Impact of lead from halide perovskites in the metabolism of living organisms." BISTUA REVISTA DE LA FACULTAD DE CIENCIAS BASICAS 18, no. 1 (July 10, 2021): 3–10. http://dx.doi.org/10.24054/01204211.v1.n1.2020.205.

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Indiscutiblemente, las perovskitas de haluro y plomo (LHPs) han sido consideradas como materiales promisorios en la fabricación de nuevos y eficientes dispositivos optoelectrónicos, con el fin de mejorar la captación de luz del sol y convertir esta energía en electricidad a bajo costo. Sin embargo, el conocimiento actual acerca de la toxicidad del plomo proveniente de las LHPs y su impacto ambiental es aun desconocido. En esta revisión, nosotros establecemos estudios relevantes, en donde ha sido observado la toxicidad del plomo proveniente de las LHPs, y su potencial acción en el metabolismo humano. Este hecho considera la urgencia de substituir el plomo por otros metales menos tóxicos, manteniendo o mejorando la eficiencia de fotoconversión. Esto hace que la tecnología basada en LHPs sea más atractiva a futuro, sea comercialmente rentable y competitiva a otras fuentes de energías alternativas.
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11

Ortíz García, Edna Z., and Andrés F. Gualdrón Reyes. "Safe or risk? Impact of lead from halide perovskites in the metabolism of living organisms." BISTUA REVISTA DE LA FACULTAD DE CIENCIAS BASICAS 18, no. 1 (July 10, 2021): 3–10. http://dx.doi.org/10.24054/bistua.v18i1.205.

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Indiscutiblemente, las perovskitas de haluro y plomo (LHPs) han sido consideradas como materiales promisorios en la fabricación de nuevos y eficientes dispositivos optoelectrónicos, con el fin de mejorar la captación de luz del sol y convertir esta energía en electricidad a bajo costo. Sin embargo, el conocimiento actual acerca de la toxicidad del plomo proveniente de las LHPs y su impacto ambiental es aun desconocido. En esta revisión, nosotros establecemos estudios relevantes, en donde ha sido observado la toxicidad del plomo proveniente de las LHPs, y su potencial acción en el metabolismo humano. Este hecho considera la urgencia de substituir el plomo por otros metales menos tóxicos, manteniendo o mejorando la eficiencia de fotoconversión. Esto hace que la tecnología basada en LHPs sea más atractiva a futuro, sea comercialmente rentable y competitiva a otras fuentes de energías alternativas.
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12

Chen, Jianbin, Hacer Koc, Shengkai Zhao, Kaiyu Wang, Lingfeng Chao, and Mustafa Eginligil. "Emerging Nonlinear Photocurrents in Lead Halide Perovskites for Spintronics." Materials 17, no. 8 (April 16, 2024): 1820. http://dx.doi.org/10.3390/ma17081820.

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Lead halide perovskites (LHPs) containing organic parts are emerging optoelectronic materials with a wide range of applications thanks to their high optical absorption, carrier mobility, and easy preparation methods. They possess spin-dependent properties, such as strong spin–orbit coupling (SOC), and are promising for spintronics. The Rashba effect in LHPs can be manipulated by a magnetic field and a polarized light field. Considering the surfaces and interfaces of LHPs, light polarization-dependent optoelectronics of LHPs has attracted attention, especially in terms of spin-dependent photocurrents (SDPs). Currently, there are intense efforts being made in the identification and separation of SDPs and spin-to-charge interconversion in LHP. Here, we provide a comprehensive review of second-order nonlinear photocurrents in LHP in regard to spintronics. First, a detailed background on Rashba SOC and its related effects (including the inverse Rashba–Edelstein effect) is given. Subsequently, nonlinear photo-induced effects leading to SDPs are presented. Then, SDPs due to the photo-induced inverse spin Hall effect and the circular photogalvanic effect, together with photocurrent due to the photon drag effect, are compared. This is followed by the main focus of nonlinear photocurrents in LHPs containing organic parts, starting from fundamentals related to spin-dependent optoelectronics. Finally, we conclude with a brief summary and future prospects.
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13

Liu, Henan, Hao Zhang, Xunling Xu, and Lin Zhang. "The Opto-Electronic Functional Devices Based on Three-Dimensional Lead Halide Perovskites." Applied Sciences 11, no. 4 (February 5, 2021): 1453. http://dx.doi.org/10.3390/app11041453.

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These days, opto-electronic functional devices based on three-dimensional lead halide perovskites (LHPs) are emerging. LHPs could be spin-coated to other materials, making it very convenient to combine LHPs with different categories of materials including metals, semiconductors, and polymers and achieve high-level performances. In this review, we will discuss the development in the LHP-based functional devices in recent years. After a brief presentation of the LHP’s properties, we will focus on the functional devices including lasers, photodetectors, and modulators. Then the fabrication of the LHP-based devices will be presented, which is followed by the summary and outlook.
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14

Xu, Jiayin, Li Zhang, and Hong Xu. "Performance of LHPs with a novel design evaporator." International Journal of Heat and Mass Transfer 55, no. 23-24 (November 2012): 7005–14. http://dx.doi.org/10.1016/j.ijheatmasstransfer.2012.07.013.

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15

Belllo, Ronke H., Mosebolatan S. David, Abiodun O. Olutayo, Khadijat O. Abdulrazaaq, Haishat Y. Olufadi–Ahmed, Omatseye T. Salami, Bilqis A. Lawal, and John O. Akerele. "Bacteriology of Some Liquid Herbal Products Sold in Ilorin- Kwara State Nigeria." Journal of Science and Practice of Pharmacy 6, no. 1 (December 11, 2019): 324–30. http://dx.doi.org/10.47227/jsppharm.v6i1.7.

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Purpose: This study aims to establish the safety and/or potential public health dangers associated with the consumption of liquid herbal preparations (LHP) sold in Ilorin-Kwara State. Methods: Ten LHPs were randomly collected from three locations, kept under cold chain and transported to the Laboratory. All samples were evaluated for bacterial load using aerobic plate count method and bacterial isolates were presumptively identified using standard microbiological methods. Furthermore, Gram negative bacteria were identified using 12A Microbact ® Identification kits. Results: Sixty percent (60%) were fresh and faint, 4 (40%) were stale and putrid in smell as well as free of foreign matter. pH and bacterial load of samples ranged from 3.60 to 9.75 and 2.5 x 102 to 4.4 x 106 CFU/ mL respectively. Five (5) genera of bacteria, namely; Klebsiella species 10 (29.41%), Bacillus subtilis 8 (23.53%), Enterobcter spps. 7 (20.59%), Staphylococcus aureus 6 (17.65%) and Serretia marcescens 3(8.82%) were isolated from these LHPs. All isolates were resistant (100%) to Sulphamethoxazole trimethoprim combination. Amoxocillin clavulanate was active against 62.50% of K. pneumonia and S. marcescens isolates. Also 50% of K. oxytoca and E. gergoviae were susceptible to Amoxocillin clavulanate combination. Approximately, 8 (80%) of LHPs had bacterial load of 2.5 x 102 to 4.4 x 106 CFU/ mL and 2 (20%) yielded no growth. In addition, 40% of LHPs had bacterial load of 106 CFU/mL beyond the 104 CFU/mL permissible limit stated by European Pharmacopoeia. Conclusion: The observed high bacterial load and the presence of S. aureus as well as enteric bacteria of public health importance in these LHPs underscore the potential risk inherent in the consumption of these preparations. Therefore, public health awareness campaign on the dangers of unapproved LHPs consumption should be instituted. Keywords: Liquid herbal preparations, bacterial contaminants, Ilorin metropolis
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Zhou, Yu, Yanming Han, Gaiyun Li, Sheng Yang, and Fuxiang Chu. "Lignin-Based Hollow Nanoparticles for Controlled Drug Delivery: Grafting Preparation Using β-Cyclodextrin/Enzymatic-Hydrolysis Lignin." Nanomaterials 9, no. 7 (July 11, 2019): 997. http://dx.doi.org/10.3390/nano9070997.

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Due to its abundance, degradability, and low toxicity, lignin is a promising raw material for the preparation of nanomaterials. However, efficient encapsulation using lignin-nanomaterial for sustained-release medications remains a challenge. This study involves grafting β-cyclodextrin (β-CD), with a hollow toroidal structure, onto the enzymatic-hydrolysis lignin (EHL) to form CD-EHL. The modified lignin was next used to prepare hollow nanoparticles (LHNPs) via self-assembly to encapsulate the antitumor drug hydroxycamptothecin (HCPT). The results indicated that β-CD improved the network structure of modified lignin molecules. Moreover, LHNPs that self-assembled using CD-EHL had an increased specific surface area and greater porosity, and exhibited a spherical hollow structure and stability in phosphate-buffered saline. The drug loading and encapsulation efficiency of HCPT were 70.6 ± 9% and 22.02 ± 2%, respectively. An in vitro study showed that lignin-based nanoparticles have low toxicity, and the modified LHNPs demonstrated a good sustained-release capability. This study broadened the potential application of lignin as a renewable biomass material.
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17

Kiinne, A., E. Pistorius, K. Kloppstech, and E. de Groot. "Circadian Synthesis of Light-Harvesting-Chlorophyll-Proteins in Euglena gracilis Is under Translational Control." Zeitschrift für Naturforschung C 53, no. 11-12 (December 1, 1998): 1017–26. http://dx.doi.org/10.1515/znc-1998-11-1213.

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Abstract Two proteins with apparent molecular masses of 17 and 24 kD that are synthesized in a circadian manner in the phytoflagellate Euglena gracilis, were recognized as proteins belong­ing to the family of light-harvesting-chlorophyll-proteins (LHCPs) of class I (17 kD) and of class II (24 kD). Identification was achieved by N-terminal sequencing of the proteins isolated from two-dimensional polyacrylamide gels and by detection with an anti-LHCP II se­rum. While it was found that the total amount of LHCPs remains almost constant, when Euglena is grown under diurnal conditions (12 h light and 12 h dark), we could show that the amount of newly synthesized 17 and 24 kD proteins varies about 20-fold with a maximum of synthesis in the light phase. In contrast, the analysis of the mRNA levels at different times revealed only minor differences in the stationary concentration of the LHCP specific mRNA, indicating that the control of LHCP synthesis is at the translational level. Principally, the same finding was obtained using inhibitors of transcription. Thus, it is concluded that the expression of LHCPs in Euglena gracilis in contrast to that of higher plants is primarily regulated at the translational level.
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18

Huang, Yongpeng, Hui Tang, Xiangyan Meng, Zitong Zhao, Yanli Liu, Dongxin Liu, Bo Chen, and Zhiyun Zou. "Development of Large Hollow Particles for Pulmonary Delivery of Cyclosporine A." Pharmaceutics 15, no. 9 (August 25, 2023): 2204. http://dx.doi.org/10.3390/pharmaceutics15092204.

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The purpose of this study was to prepare large hollow particles (LHPs) by spray drying for pulmonary delivery of cyclosporine A (CsA), using L-Leucine (LEU) and hydroxypropyl methylcellulose (HPMC) as excipients and ammonium bicarbonate (AB) as a porogen. The prepared LHPs were spherical particles composed of both CsA and LEU on the surface and HPMC on the inner layer. The formulation of CsA-LEU-0.8HPMC-AB as typical LHPs showed excellent in vitro aerodynamic performance with a minimum mass median aerodynamic diameter (MMAD) of 1.15 μm. The solubility of CsA-LEU-0.8HPMC-AB was about 5.5-fold higher than that of raw CsA, and the dissolution of CsA-LEU-0.8HPMC-AB suggested that the drug was released within 1 h. The cell viability of the A549 cell line showed that CsA-LEU-0.8HPMC-AB was safe for delivering CsA to the lungs. In addition, inhalation administration of CsA-LEU-0.8HPMC-AB with the Cmax and AUC0–∞ increasing by about 2-fold and 2.8-fold compared with the oral administration of Neoral® could achieve therapeutic drug concentrations with lower systemic exposure and significantly improve the in vivo bioavailability of CsA. From these findings, the LHPs, with the advantage of avoiding alveolar macrophage clearance, could be a viable choice for delivering CsA by inhalation administration relative to oral administration.
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19

Xiao, Luyao, Xiaojia Ge, Lin Yang, Xiaohong Chen, Qian Xu, Xin Rui, Xia Fan, et al. "Anticancer potential of an exopolysaccharide from Lactobacillus helveticus MB2-1 on human colon cancer HT-29 cells via apoptosis induction." Food & Function 11, no. 11 (2020): 10170–81. http://dx.doi.org/10.1039/d0fo01345e.

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20

Tang, Wenjie, Yue Wu, Tingting Gao, Yingqin Wei, and Guowei Zhou. "Facile preparation of hybrid porous polyanilines for highly efficient Cr(vi) removal." RSC Advances 8, no. 58 (2018): 33217–27. http://dx.doi.org/10.1039/c8ra07026a.

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In the present work, leucoemeraldine-based hybrid porous polyanilines (LHPPs) have been synthesized by the Friedel–Crafts reaction of leucoemeraldine and octavinylsilsesquioxane (OVS) for Cr(vi) removal.
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21

Raman, Subashini, Syed Mahmood, and Azizur Rahman. "A Review on Lipid- Polymer Hybrid Nanoparticles and Preparation with Recent Update." Materials Science Forum 981 (March 2020): 322–27. http://dx.doi.org/10.4028/www.scientific.net/msf.981.322.

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Ongoing progression in nanotechnology has demonstrated that nanoparticles have indicated promising potential as in delivering the drug. The acceptance of nanoparticles and their applications also reported in clinical advancement to upgrade and improve the pharmacokinetic and pharmacodynamics properties of therapeutic compounds. In this review, we talk about the next-generation core-shell nanostructures like lipid-polymer hybrid nanoparticles (LHNPs) and their application and formulation aspects. Conceptually, derived from both polymeric nanoparticles and liposome, which gave them a name of hybrid nanoparticles. It is basically polymer core enveloped by a lipid layer. The major issue arises with nanoparticles with polymer is related to entrapment efficiency and LHNPs have proved to solve this issue to a vast extent, due to their hybrid components.
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22

Maehrlein, Sebastian F., Prakriti P. Joshi, Lucas Huber, Feifan Wang, Marie Cherasse, Yufeng Liu, Dominik M. Juraschek, et al. "Decoding ultrafast polarization responses in lead halide perovskites by the two-dimensional optical Kerr effect." Proceedings of the National Academy of Sciences 118, no. 7 (February 8, 2021): e2022268118. http://dx.doi.org/10.1073/pnas.2022268118.

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The ultrafast polarization response to incident light and ensuing exciton/carrier generation are essential to outstanding optoelectronic properties of lead halide perovskites (LHPs). A large number of mechanistic studies in the LHP field to date have focused on contributions to polarizability from organic cations and the highly polarizable inorganic lattice. For a comprehensive understanding of the ultrafast polarization response, we must additionally account for the nearly instantaneous hyperpolarizability response to the propagating light field itself. While light propagation is pivotal to optoelectronics and photonics, little is known about this in LHPs in the vicinity of the bandgap where stimulated emission, polariton condensation, superfluorescence, and photon recycling may take place. Here we develop two-dimensional optical Kerr effect (2D-OKE) spectroscopy to energetically dissect broadband light propagation and dispersive nonlinear polarization responses in LHPs. In contrast to earlier interpretations, the below-bandgap OKE responses in both hybrid CH3NH3PbBr3 and all-inorganic CsPbBr3 perovskites are found to originate from strong hyperpolarizability and highly anisotropic dispersions. In both materials, the nonlinear mixing of anisotropically propagating light fields results in convoluted oscillatory polarization dynamics. Based on a four-wave mixing model, we quantitatively derive dispersion anisotropies, reproduce 2D-OKE frequency correlations, and establish polarization-dressed light propagation in single-crystal LHPs. Moreover, our findings highlight the importance of distinguishing the often-neglected anisotropic light propagation from underlying coherent quasiparticle responses in various forms of ultrafast spectroscopy.
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Kohorn, B. D., E. Harel, P. R. Chitnis, J. P. Thornber, and E. M. Tobin. "Functional and mutational analysis of the light-harvesting chlorophyll a/b protein of thylakoid membranes." Journal of Cell Biology 102, no. 3 (March 1, 1986): 972–81. http://dx.doi.org/10.1083/jcb.102.3.972.

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The precursor for a Lemna light-harvesting chlorophyll a/b protein (pLHCP) has been synthesized in vitro from a single member of the nuclear LHCP multigene family. We report the sequence of this gene. When incubated with Lemna chloroplasts, the pLHCP is imported and processed into several polypeptides, and the mature form is assembled into the light-harvesting complex of photosystem II (LHC II). The accumulation of the processed LHCP is enhanced by the addition to the chloroplasts of a precursor and a co-factor for chlorophyll biosynthesis. Using a model for the arrangement of the mature polypeptide in the thylakoid membrane as a guide, we have created mutations that lie within the mature coding region. We have studied the processing, the integration into thylakoid membranes, and the assembly into light-harvesting complexes of six of these deletions. Four different mutant LHCPs are found as processed proteins in the thylakoid membrane, but only one appears to have an orientation in the membrane that is similar to that of the wild type. No mutant LHCP appears in LHC II. The other two mutant LHCPs cannot be detected within the chloroplasts. We conclude that stable complex formation is not required for the processing and insertion of altered LHCPs into the thylakoid membrane. We discuss the results in light of our model.
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TAKEDA, KATSUYUKI. "Clinical evaluation test for male pattern alopecia of LHOP pharmaceuticals." Nishi Nihon Hifuka 55, no. 4 (1993): 727–34. http://dx.doi.org/10.2336/nishinihonhifu.55.727.

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25

Pastukhov, V. G., and Y. F. Maydanik. "Active coolers based on copper–water LHPs for desktop PC." Applied Thermal Engineering 29, no. 14-15 (October 2009): 3140–43. http://dx.doi.org/10.1016/j.applthermaleng.2009.04.016.

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26

Li, Wei, Juan Ji, Weizhi Tang, Xin Rui, Xiaohong Chen, Mei Jiang, and Mingsheng Dong. "Characterization of an antiproliferative exopolysaccharide (LHEPS-2) from Lactobacillus helveticus MB2-1." Carbohydrate Polymers 105 (May 2014): 334–40. http://dx.doi.org/10.1016/j.carbpol.2014.01.093.

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27

Li, Shu Qing, Shui Li Gong, Yu Ping Duan, and Shun Hua Liu. "Influence of Laser Power on the Microstructure and Anti-Corrosion Performance of LHPS NiCrAlY Coatings." Advanced Materials Research 415-417 (December 2011): 221–25. http://dx.doi.org/10.4028/www.scientific.net/amr.415-417.221.

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The NiCrAlY coatings were deposited on 38CrMoAl substrate by a laser hybrid plasma spraying (LHPS) technology in this study. The coatings’ microstructures and anti-corrosion performances with different laser power were characterized using an optical microscope, a scanning electron microscope, and the Neutral Salt Spray(NSS) test. The test results indicate that the laser power has great effect on the microstructure and performances of the LHPS coatings. And when the laser power is appropriate, it can make the coating has more compact and homogeneous microstructure, exhibit less porosities or micro-cracks, higher bonding strength and more excellent anti-corrosion performance.
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Luo, Binbin, Ruosheng Zeng, and Feiming Li. "Editorial on the Special Issue “Advances of Low-Dimensional Metal Halide Perovskite Materials”." Crystals 13, no. 2 (February 18, 2023): 350. http://dx.doi.org/10.3390/cryst13020350.

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Li, Shu Qing, Shun Hua Liu, Qi Lian Li, and Yu Ping Duan. "Influence of Laser Power on the Microstructure and Anti-Wear Performance of Laser Hybrid Plasma Spraying NiCr-Cr3C2 Coatings." Advanced Materials Research 1015 (August 2014): 119–23. http://dx.doi.org/10.4028/www.scientific.net/amr.1015.119.

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The NiCr-Cr3C2 coatings were deposited on 38CrMoAl substrate by a laser hybrid plasma spraying (LHPS) technology in this study. The coatings’ microstructures and anti-wear performances with different laser power were characterized using an optical microscope, a scanning electron microscope, and the SRV test. The test results indicated that the laser power has great effect on the microstructure and performances of the LHPS coatings. And when the laser power is at the appropriate value, it can make the coating have more compact and homogeneous microstructure, exhibit less pores or micro-cracks, and the higher bonding strength and more excellent anti-wear performance of the coating are achieved.
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30

Zhou, Yu, Yanming Han, Gaiyun Li, and Fuxiang Chu. "Effects of Lignin-Based Hollow Nanoparticle Structure on the Loading and Release Behavior of Doxorubicin." Materials 12, no. 10 (May 24, 2019): 1694. http://dx.doi.org/10.3390/ma12101694.

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Because of their exceptional absorption capacity, biodegradability, and nontoxicity, nanomaterials fabricated from renewable natural resources have recently become an increasingly important research area. However, the mechanism of drug encapsulation by lignin nanoparticles and the role of nanoparticle structure on the stability and loading performance still remain unknown. Herein, lignin hollow nanoparticles (LHNPs) were prepared and applied as promising vehicles for the antineoplastic antibiotic drug doxorubicin hydrochloride (DOX). The hydrogen bonding and π−π interactions contributed to the encapsulation of hydrophilic DOX by LHNPs with hydrophobic cavities. The encapsulation of DOX was enhanced by the pore volume and surface area. In addition, the nanoparticles contributed to the cellular uptake and the accumulation of the drug within HeLa cells. This work provides a scientific basis for future studies on the selective entrapment properties of hollow polymer nanoparticles derived from biomass material as vehicles for overcoming pharmacokinetic limitations.
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Guo, Zhendong, Jing Wang, and Wan-Jian Yin. "Atomistic origin of lattice softness and its impact on structural and carrier dynamics in three dimensional perovskites." Energy & Environmental Science 15, no. 2 (2022): 660–71. http://dx.doi.org/10.1039/d1ee02131a.

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32

Lee, Se-Rin, Do-Young Kim, Jae-Geun Jung, Hyeon-Woo Kim, Byeong-Hyeon Lee, and Min-Ho Park. "Recent Progress of Eco-friendly Lead-free Halide Perovskite Light-Emitting Diodes." Ceramist 25, no. 3 (September 30, 2022): 332–55. http://dx.doi.org/10.31613/ceramist.2022.25.3.03.

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Metal halide perovskites (MHPs) are promising candidate materials for next-generation optoelectronic device applications such as light-emitting diodes (LEDs), solar cells, and photodetectors. However, the toxicity and poor stability issues of lead-based MHPs (LHPs) are still challenging to fulfill a restriction of hazardous substances directive (RoHS) and industrial standards for the commercialization of LHP devices. Therefore, eco-friendly and lead-free halide perovskites (EHPs), which are superior to LHPs, should be developed. In this review, we will review the promising strategies to substitute a lead cation with non-toxic metal cations such as tin (Sn), bismuth (Bi), antimony (Sb), and copper (Cu), and discuss the synthetic methods, crystal structures, luminescent properties, and their LED applications.
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Szymanski, Pawel, Dariusz Mikielewicz, and Sasan Fooladpanjeh. "Current Trends in Wick Structure Construction in Loop Heat Pipes Applications: A Review." Materials 15, no. 16 (August 21, 2022): 5765. http://dx.doi.org/10.3390/ma15165765.

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Thermal control systems have been introduced as an important part of electronic devices, enabling thermal management of their electronic components. Loop heat pipe (LHP) is a passive two-phase heat transfer device with significant potential for numerous applications, such as aerospace applications, high-power LEDs, and solar central receivers. Its advantages are high heat transfer capability, low thermal resistance, long-distance heat transfer, and compact structure. The essential role of wick structures on the performance of LHPs has already been highlighted, but no comprehensive review is available that deals with different parameters such as LHP design and wick size, which are largely decisive and effective in achieving a practical level of thermal transmission governed by wick structures. To rely on this necessity, this article summarizes, analyzes, and classifies advancements in the design and fabrication of wick structures. The main conclusion to be drawn after careful monitoring and weighing of the related literature is that LHPs with composites and additively manufactured wicks show a higher heat transfer coefficient than other conventional structures. Indeed, future works should be focused on the design of more structurally efficient wicks, which may allow us to optimize materials and geometrical parameters of wick structure for higher heat transfer through LHPs.
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34

Roh, Doe Kywn, Dong Won Lee, Jong Yuk Yi, Chul Jong Park, Baik Kee Cho, Chung Won Kim, and Tae Yoon Kim. "A Clinical Study of Pentadecanoic Glyceride(LHOP) on Male Pattern Alopecia." Journal of Korean Society for Clinical Pharmacology and Therapeutics 6, no. 2 (1998): 199. http://dx.doi.org/10.12793/jkscpt.1998.6.2.199.

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35

Zhou, Yu, Yanming Han, Gaiyun Li, Sheng Yang, Fuquan Xiong, and Fuxiang Chu. "Preparation of Targeted Lignin–Based Hollow Nanoparticles for the Delivery of Doxorubicin." Nanomaterials 9, no. 2 (February 2, 2019): 188. http://dx.doi.org/10.3390/nano9020188.

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Due to their exceptional absorption capacity, biodegradability, and non-toxicity, nanoparticles (NPs) from lignin have emerged as vehicles for inorganic particles and drug molecules. However, the method for preparing targeted lignin particles is still complex and lacks sufficient research. Herein, a succinct strategy was proposed for the preparation of targeted lignin-based drug delivery NPs to load Doxorubicin Hydrochloride (DOX). The lignin hollow NPs (LHNPs) were used as a platform for the preparation of targeted delivery material by incorporating magnetic NPs and folic acid (FA) via layer-by-layer self-assembling. The results showed that the surface of LHNPs was covered uniformly by Fe3O4 NPs and grafted with folic acid. The folic-magnetic-functionalized lignin hollow NPs (FA-MLHNPs) could respond to magnetic field and folic acid receptors. In addition, the targeting performance of the FA-MLHNPs increased the cellular uptake of NPs in the case of HeLa cells. This research not only supported the modified NPs platform as a highly efficient nano-delivery method but also provided a facile approach to utilize renewable lignin biomaterials.
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36

Senarath Jayasinghe, Ruchini, and Nirodha Gayani Fernando. "Developing labour productivity norms for aluminium system formwork in Sri Lanka." Built Environment Project and Asset Management 7, no. 2 (May 11, 2017): 199–211. http://dx.doi.org/10.1108/bepam-09-2015-0049.

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Purpose The purpose of this paper is to establish labour productivity norms (LPNs) on an elemental basis to investigate a measurement for the labour productivity (LP) of aluminium system formwork (ASF) in low-cost housing projects (LHPs) in Sri Lanka. Design/methodology/approach Case study approach was selected as the most appropriate for the study and semi-structured interviews, document review and direct observations were used for the data collection. Four case studies were conducted. Eight semi-structured interviews were conducted among four cases. Further, document review was used in three cases, and direct observation was used in one case. The validation of the results was not possible in a real life project due to time limitations. Findings The findings identified six labour productivity factors (LPFs) affecting the LP of ASF. The need for LPNs for ASF on an elemental basis is identified. Further, LPNs were developed using LPFs. Research limitations/implications This research was limited to LHPs for underserved settlements in Colombo, Sri Lanka which use ASF. The LPNs were prepared based on time studies and were restricted to structural elements such as slabs, beams and columns. Originality/value The LPNs were developed for ASF in LHPs based on the effect of weather, crew, site, management and project factors. Further, the study addresses a gap in the literature regarding the development of LPNs of ASF for LPHs in Sri Lanka. LPNs for ASF have enhanced LP while promoting economic and social stability in the industry.
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37

Zhu, Mo, Nairong Hao, Jinxian Yang, and Lianwei Li. "A comparative study of intrachain cyclization and solution properties of long-subchain hyperbranched polymers prepared via Y-type and V-type macromonomer approaches." Polymer Chemistry 9, no. 20 (2018): 2830–42. http://dx.doi.org/10.1039/c8py00362a.

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V-type (B∼∼A∼∼B) and Y-type (A∼∼∼∼B2) macromonomer approaches are two of the most widely adopted synthetic methodologies for the preparation of long-subchain hyperbranched polymers (LHPs) with a controlled subchain length.
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38

Muhammad, Fazal, Farman Ali, Ghulam Abbas, Ziaul Haq Abbas, Shahab Haider, Muhammad Bilal, Md Jalil Piran, and Doug Young Suh. "Palliation of Four-Wave Mixing in Optical Fibers Using Improved DSP Receiver." Electronics 10, no. 5 (March 5, 2021): 611. http://dx.doi.org/10.3390/electronics10050611.

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A long haul optical communication system (LHOCS) is one of the key resources to fulfill the higher capacity requirements in future communication networks. To launch LHOCS, the system mainly faces high order nonlinear effects. The four-wave mixing (FWM) is one of the major nonlinear effects, which limits the transmission distance. Therefore, in this paper, an advanced duo-binary (DB) modulation scheme-based system is evaluated by employing an improved digital signal processing (IDSP) approach at the receiver side to suppress the FWM effect. In addition, an analytical analysis is also performed for the proposed system. To observe the difference between the IDSP and conventional digital signal processing (DSP), the various performance metrics such as bit error rate (BER), Q-factor, and optical signal-to-noise ratio (OSNR) parameters are evaluated. Variable channel spacing along with polarization mode dispersion (PMD) are analyzed at several ranges of input powers and fiber lengths. The analytical and simulation-based calculations exhibit the effectiveness of the proposed model and hence, FWM effect are compensated to achieve 500 km optical fiber propagation range with a BER below 10−6.
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39

Dey, Amrita, Simone Strohmair, Fei He, Quinten A. Akkerman, and Jochen Feldmann. "Fast electron and slow hole spin relaxation in CsPbI3 nanocrystals." Applied Physics Letters 121, no. 20 (November 14, 2022): 201106. http://dx.doi.org/10.1063/5.0103102.

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Spin-dependent properties of lead halide perovskites (LHPs) have recently gained significant attention paving their way toward spin-optoelectronic applications. However, separate measurements of the electron and hole spin relaxation rates are so far missing in LHPs. The knowledge of the electron and hole spin relaxation timescales is necessary to understand the spin-dependent properties of LHPs. Here, we report on the spin polarization dynamics in CsPbI3 nanocrystals (NCs). We employ polarization dependent ultrafast differential transmission spectroscopy (DTS) at room temperature to study the spin polarization dynamics in this system. In the case of pure CsPbI3 NCs, it is not possible to measure separately electron and hole spin relaxation rates from the polarization dependent DTS. Here, we introduce the soluble fullerene derivative PC60BM as an electron acceptor along with CsPbI3 to create an imbalance between the photoexcited electrons and holes in the NCs and, thus, affecting their spin-dependent carrier distribution. CsPbI3:PC60BM blend sample shows a distinct difference in the spin dependent kinetics of the DTS spectra as compared to the NCs-only sample. With the help of a kinetic model for the spin-dependent charge carrier distributions, we separately determine the electron and hole spin relaxation times in CsPbI3 NCs. We find that the room temperature hole spin lifetime ( τh ∼ 5 ps) is ∼13 times longer than the electron spin lifetime ( τe ∼ 0.4 ps). We ascribe the fast electron spin relaxation to the presence of strong spin–orbit coupling in the conduction band, which is ineffective for holes in the s-type valence band.
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40

Rogério Kurz, Marcio, and Nanci Stancki da Luz. "Divisão sexual do trabalho no brasil: mulher cuidadora e homem provedor?" Cadernos de Gênero e Tecnologia 8, no. 29/30 (June 1, 2014): 55. http://dx.doi.org/10.3895/cgh.v8n29/30.6127.

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Um aspecto marcante do mundo do trabalho é o acentuado crescimento da participação feminina, aumento acompanhado pela ampliação do nú- mero de domicílios che ados por mulheres e da sua contribuição para a renda familiar, alterando, de alguma forma, a tradicional divisão sexual do trabalho, que atribui à mulher a função de cuidadora e ao homem a função de provedor do lar. A redução do número de lhos, o aumento das famílias sem lhos e de famílias monoparentais são alterações que in uenciaram em outras formas de arranjos familiares. Este estudo quantitativo, apoiado na estatística descritiva, buscou conhecer e comparar diversos aspectos nas relações e realidades das mulheres no mundo do trabalho, sob a ótica da divisão sexual do trabalho, em um período de 10 anos no Brasil. Os dados são da Pesquisa Nacional por Amostra de Domicílios (PNAD) do Instituto Brasileiro de Geogra a e Estatística (IBGE) para os anos de 2002 e 2011.
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41

Rogério Kurz, Marcio, and Nanci Stancki da Luz. "Divisão sexual do trabalho no brasil: mulher cuidadora e homem provedor?" Cadernos de Gênero e Tecnologia 8, no. 29/30 (June 1, 2014): 55. http://dx.doi.org/10.3895/cgt.v8n29/30.6127.

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Um aspecto marcante do mundo do trabalho é o acentuado crescimento da participação feminina, aumento acompanhado pela ampliação do nú- mero de domicílios che ados por mulheres e da sua contribuição para a renda familiar, alterando, de alguma forma, a tradicional divisão sexual do trabalho, que atribui à mulher a função de cuidadora e ao homem a função de provedor do lar. A redução do número de lhos, o aumento das famílias sem lhos e de famílias monoparentais são alterações que in uenciaram em outras formas de arranjos familiares. Este estudo quantitativo, apoiado na estatística descritiva, buscou conhecer e comparar diversos aspectos nas relações e realidades das mulheres no mundo do trabalho, sob a ótica da divisão sexual do trabalho, em um período de 10 anos no Brasil. Os dados são da Pesquisa Nacional por Amostra de Domicílios (PNAD) do Instituto Brasileiro de Geogra a e Estatística (IBGE) para os anos de 2002 e 2011.
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42

Ning, Weihua, Jinke Bao, Yuttapoom Puttisong, Fabrizo Moro, Libor Kobera, Seiya Shimono, Linqin Wang, et al. "Magnetizing lead-free halide double perovskites." Science Advances 6, no. 45 (November 2020): eabb5381. http://dx.doi.org/10.1126/sciadv.abb5381.

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Spintronics holds great potential for next-generation high-speed and low–power consumption information technology. Recently, lead halide perovskites (LHPs), which have gained great success in optoelectronics, also show interesting magnetic properties. However, the spin-related properties in LHPs originate from the spin-orbit coupling of Pb, limiting further development of these materials in spintronics. Here, we demonstrate a new generation of halide perovskites, by alloying magnetic elements into optoelectronic double perovskites, which provide rich chemical and structural diversities to host different magnetic elements. In our iron-alloyed double perovskite, Cs2Ag(Bi:Fe)Br6, Fe3+ replaces Bi3+ and forms FeBr6 clusters that homogenously distribute throughout the double perovskite crystals. We observe a strong temperature-dependent magnetic response at temperatures below 30 K, which is tentatively attributed to a weak ferromagnetic or antiferromagnetic response from localized regions. We anticipate that this work will stimulate future efforts in exploring this simple yet efficient approach to develop new spintronic materials based on lead-free double perovskites.
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43

Cho, Han Bin, and Won Bin Im. "Enhanced Phase, Thermal and Aqueous Stability of the Embedded the CsPbI3 Ncs in Cs4PbI6 Ncs." ECS Meeting Abstracts MA2022-02, no. 51 (October 9, 2022): 1987. http://dx.doi.org/10.1149/ma2022-02511987mtgabs.

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Increasing the stability of lead halide perovskites (LHPs) is required for integrating them into light-emitting devices. To date, most studies toward this direction have primarily concentrated on improving the chemical stability of green-emitting LHPs. In this work, red-emitting CsPbI3–Cs4PbI6 hybrid nanocrystals (NCs) were synthesized with a high photoluminescence (PL) quantum yield of ∼90%. Their hybrid structure was examined via structural (Rietveld) refinement analysis and transmission electron microscopy. Rietveld refinement also revealed that the black polymorph of CsPbI3 NCs is an orthorhombic perovskite rather than a cubic one. The thermodynamic stability of the CsPbI3 NCs in Cs4PbI6 matrices is enhanced in both solutions and films for up to several weeks. The enhanced stability of the embedded CsPbI3 NCs is attributed to the lowering of their Gibbs free energy, as determined on the basis of experimental data. Additionally, the hybrid NCs exhibit unprecedented emission stability—maintaining 65% of their original PL efficiency at 150 °C—and improved aqueous stability.
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44

Wang, Jia-Xin, Chang Liu, Hao Huang, Rui He, Shengyong Geng, and Xue-Feng Yu. "Microencapsulation of Lead-Halide Perovskites in an Oil-in-Fluorine Emulsion for Cell Imaging." Nanomaterials 13, no. 9 (May 4, 2023): 1540. http://dx.doi.org/10.3390/nano13091540.

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The superior optical properties of lead-halide perovskites (LHPs) inspired significant research in cell imaging applications; many encapsulating processes have improved perovskite stabilities with comparable biosafety. Herein, facile solvent evaporation encapsulation based on an oil-in-fluorine emulsion for aqueous-stable and extremely nontoxic LHP microcapsules is described. Perfluorooctane dispersed the emulsifier fluorocarbon surfactant to form a continuous fluorine phase, while LHPs and polymethylmethacrylate (PMMA) were dispersed in 1,2-dichloroethane, then emulsified in the fluorine phase to form an oil-in-fluorine emulsion. CsPbBr3 microcapsules with a dense PMMA shell that protect fragile CsPbBr3 from the external environment and inhibit lead ion release were obtained after solvent evaporation. The CsPbBr3 microcapsules not only retained 91% of fluorescence intensity after exposure to water for 30 d but also possess extremely low cytotoxicity for MCF-7 cells. After exposure to 2 mg/mL of CsPbBr3 microcapsules for 48 h, the cell viability remained >90%. The intracellular uptake of CsPbBr3 microcapsules indicates its potential use in cell imaging.
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45

De Oliveira, Ana Luísa Botta Martins, and Moacyr Torres Júnior. "Influência de medidas preventivas na infecção oral primária em crianças." Revista de Odontologia da Universidade Cidade de São Paulo 26, no. 2 (November 28, 2017): 133. http://dx.doi.org/10.26843/ro_unicid.v26i2.292.

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O presente trabalho é uma revisão da literatura com o objetivo de observar a transmissão de doenças infecciosas orais através do contato entre mãe e fi lho e a infl uência de medidas preventivas para evitar possíveis doenças. Por meio da literatura revisada pode-se observar uma “relação vertical” de transmissibilidade da cárie caracterizada pela transferência materna de microorganismos cariogênicos para os seus fi lhos; medidas preventivas, as quais reduzem o nível salivar de Streptococus mutans em mulheres, retardam a colonização em suas crianças por esses organismos; alertar para a necessidade do desenvolvimento de programas educativos voltados para os pais e preventivos voltados para os bebês, procurando estabelecer hábitos saudáveis para evitar a contaminação da cavidade bucal da criança e oferecer a verdadeira promoção de saúde. Concluiu-se que a transmissibilidade da cárie apresenta relação-vertical, tendo a mãe papel de destaque na infecção oral primária de seus fi lhos. Medidas educativas e preventivas junto às mães, desde o período gestacional, são alternativas plausíveis e viáveis para a manutenção de um equilíbrio satisfatório das condições orais na criança
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46

Albrecht, Marisa S., and Teresa Kleba Lisboa. "DECIFRANDO A DIVISÃO DO TRABALHO DOMÉSTICO NAS UNIDADES FAMILIARES DO BALNEÁRIO INGLESES: COTIDIANO E RELAÇÕES DE GÊNERO." Revista Grifos 20, no. 30/31 (October 8, 2014): 103. http://dx.doi.org/10.22295/grifos.v20i30/31.2412.

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O presente artigo é uma síntese da dissertação de mestrado defendida junto ao Programa de Pós Graduação em Serviço Social da UFSC e teve como objetivo conhecer as diferentes perspectivas sobre a divisão do trabalho doméstico, de homens e mulheres casados ou que vivem com uma companheira, em que ambos exercem uma ocupação remunerada e possuem fi lhos em idade escolar. Tivemos como norte as seguintes questões: 1) Como ocorre a divisão do trabalho doméstico entre casais com fi lhos em que ambos exercem uma ocupação remunerada? 2) Quais os principais desafios que homens e mulheres encontram para conciliar suas ocupações no espaço público e dividir o trabalho doméstico? Os sujeitos desta pesquisa foram 15 homens e 17 mulheres moradores do Balneário de Ingleses (Florianópolis/SC). Para a coleta dos dados, realizamos entrevistas semi estruturadas e aplicação de questionário. Concluímos que as mulheres continuam assumindo o trabalho doméstico e o cuidado em relação aos idosos, doentes e crianças, preenchendo através de sua dupla ou tripla jornada as lacunas deixadas por seus companheiros, bem como pela ausência das políticas públicas.
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47

Viana, Maria José Braga. "Disposições temporais de futuro e longevidade escolar em famílias populares." Perspectiva 27, no. 1 (April 30, 2010): 195–215. http://dx.doi.org/10.5007/2175-795x.2009v27n1p195.

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Neste trabalho descrevo resultados de duas investigações que abordam uma problemática de fundo comum: as condições que possibilitam o fenômeno, estatisticamente improvável, da longevidade escolar em meios populares. Mais especifi camente, busco identifi car nas práticas socializadoras de famílias populares um espaço de constituição de disposições facilitadoras de longevidade escolar nesses meios. Defendo que esta seria uma das formas por meio das quais as famílias populares estariam presentes na escolarização prolongada de seus fi lhos. Dentreos tipos de disposições investigados destaco, para esse trabalho, as temporais. Em pesquisa mais recente estudei sete casos de estudantes do Curso de Pedagogia da FaE/UFMG dos anos de 2002 e 2003, via entrevistas; esses sujeitos foram selecionados no interior de um corpus de 120 autobiografi as escolares produzidas de forma escrita. Embora focando os dados das entrevistas, a análise que aqui se desenvolve considera também elementos dessas autobiografi as, assim como das trajetórias de dois casos de uma pesquisa anterior. Uma conclusão mais geral desses estudos: existe, nessas famílias, um horizonte de futuro distendido – disposição que é atípica para os meios populares –, expresso, sobretudo, na possibilidade de uma vida melhor para os fi lhos via escola.
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48

Cohen, Samuel A., Daniel A. Portney, Landon E. Cohen, Ioanna Bolia-Kavouklis, Alexander E. Weber, and Matthew D. Saltzman. "Using Pitch-Tracking Data to Identify Risk Factors for Medial Ulnar Collateral Ligament Reconstruction in Major League Baseball Pitchers." Orthopaedic Journal of Sports Medicine 10, no. 3 (March 1, 2022): 232596712110657. http://dx.doi.org/10.1177/23259671211065756.

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Background: Approximately 25% of Major League Baseball (MLB) pitchers undergo medial ulnar collateral ligament reconstruction (UCLR) during their careers. Purpose: To identify risk factors for UCLR that are specific to 2 subgroups of MLB pitchers: right (RHPs)- versus left-handed pitchers (LHPs) and starting (SPs) versus relief pitchers (RPs). Study Design: Case-control study; Level of evidence, 3. Methods: We included 109 MLB pitchers who had undergone UCLR between 2007 and 2019 and had sufficient preinjury data in the 3 years before surgery (T3, T2, T1). A 2:1 matched control cohort was selected for comparison. Pitch velocity, release location, and ball movement were compared between the UCLR and control cohorts in both subgroups in the years before surgery (RHPs vs LHPs and SPs vs RPs). Binary logistic regression was used to identify independent risk factors for UCLR. Results: The mean horizontal release location for the UCLR group was 5.8 cm more lateral than for the control group ( P = .028). For all pitchers, every 2.5-cm lateral shift in release location in the years leading up to UCLR equated to a 3.7% increase in the odds of UCLR. For RPs, this risk was more substantial: a 5.8% increase in odds per 2.5 cm. SPs in the UCLR group demonstrated significantly different T1 horizontal release locations compared with SPs in the control group, though not to a statistically significant change over the 3 years before surgery. However, in the 3 years before surgery, the horizontal release location for RPs in the UCLR group moved 2.1 cm more lateral, as compared with 2.7 cm more medial for RPs in the control group ( P = .007). For LHPs, a decrease in mean pitch velocity by 1 mph (1.6 km/h) in the years leading up to surgery increased the odds of UCLR by 45%. Conclusion: Increasing lateralization of release point in the years before surgery increased the risk of UCLR, specifically for relievers. Our findings add to the growing body of evidence that release location is an important variable in analyzing the risk of UCLR in MLB and that risk stratification may be dependent on pitcher characteristics such as position, handedness, and weight.
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49

Pereira, Madian De Jesus Frazão. "“Filhos do Rei Sebastião”, “Filhos da Lua”: construções simbólicas sobre os nativos da Ilha dos Lençóis." Cadernos de Campo (São Paulo, 1991) 13, no. 13 (March 30, 2005): 61. http://dx.doi.org/10.11606/issn.2316-9133.v13i13p61-74.

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Este artigo aborda a construção doimaginário de uma ilha considerada “encantada”: a Ilha dos Lençóis, no Estado do Maranhão. Apresen- ta uma simbologia sobre os ilhéus, principalmente acerca daqueles singularizados por marcas corporais, os albinos. Enfatiza a compreensão explicativa das práticas discursivas do “universo de fora” (sobretu- do matérias veiculadas na imprensa de uma manei- ra geral) e do “universo de dentro” (representações nativas) sobre duas denominações que sintetizam o imaginário sobre os albinos da Ilha dos Lençóis: “fi- lhos da Lua” e “filhos do Rei Sebastião”.
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50

Severo, Helena. "Sobre Celeida." arte e ensaios 2, no. 2 (August 11, 2022): 6–9. http://dx.doi.org/10.37235/ae.n2.2.

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O que mais me impressiona nos traba­ lhos de Celeida Tostes é a vitalidade e a urgência que eles respiram. E o que mais me impressionava na figura de Celeida era sua generosidade, que ela distribuía em tomo de si, onde quer que estivesse, como se fosse a coisa mais natural do mundo. E, no seu caso, urgência, vitalidade e generosi­ dade me parecem ser características complementares que ligam a persona­ lidade da artista à sua obra, uma expli­ cando a outra de maneira indissociá­vel.
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