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Relevant bibliographies by topics / Leukaemic Stem Cells

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Academic literature on the topic 'Leukaemic Stem Cells'

Author: Grafiati

Published: 14 March 2023

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Journal articles on the topic "Leukaemic Stem Cells"

1

Sarrou, Evgenia, Laura Richmond, Ruaidhrí J. Carmody, Brenda Gibson, and Karen Keeshan. "CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis." International Journal of Molecular Sciences 21, no. 12 (2020): 4266. http://dx.doi.org/10.3390/ijms21124266.

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Chromosomal rearrangements of the mixed lineage leukaemia (MLL, also known as KMT2A) gene on chromosome 11q23 are amongst the most common genetic abnormalities observed in human acute leukaemias. MLL rearrangements (MLLr) are the most common cytogenetic abnormalities in infant and childhood acute myeloid leukaemia (AML) and acute lymphocytic leukaemia (ALL) and do not normally acquire secondary mutations compared to other leukaemias. To model these leukaemias, we have used clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing to induce MLL-AF9 (MA9) chromosomal r

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Blair, A., and D. H. Pamphilon. "Leukaemic stem cells." Transfusion Medicine 13, no. 6 (2003): 363–75. http://dx.doi.org/10.1111/j.1365-3148.2003.00464.x.

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Shlush, L. I., and T. Feldman. "The evolution of leukaemia from pre‐leukaemic and leukaemic stem cells." Journal of Internal Medicine 289, no. 5 (2021): 636–49. http://dx.doi.org/10.1111/joim.13236.

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Lutz, Christoph, Petter Woll, Anders Castor, et al. "Selective Persistence of Distinct Stem/B Leukaemic Stem Cells In Childhood Acute Lymphoblastic Leukaemia In Clinical Remission." Blood 116, no. 21 (2010): 1585. http://dx.doi.org/10.1182/blood.v116.21.1585.1585.

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Abstract Abstract 1585 Recent studies utilising surrogate leukaemic stem cell (LSC) assays have suggested that LSCs in acute lymphoblastic leukaemias (ALLs) might be neither rare, nor phenotypically or functionally distinct. However, studies of candidate LSCs in surrogate assays might not recapitulate the full leukaemic potential of candidate LSCs in patients, and in particular their responsiveness and resistance to therapeutic targeting. Therefore, we have investigated the identity, molecular and functional properties, and persistence of different subsets of candidate LSCs in childhood ALL, a

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Noman, Helal Mohammed Mohammed Ahmed, Yahya Saleh Al-Matary, Subbaiah Chary Nimmagadda, et al. "Leukaemia Cells Induced Metabolic Alterations in AML Associated Mesenchymal Stem Cells Via Notch Signalling." Blood 138, Supplement 1 (2021): 4347. http://dx.doi.org/10.1182/blood-2021-144468.

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Abstract Introduction: Acute myeloid leukaemia (AML) is a haematological malignancy with a high relapse rate and poor prognosis. Leukaemia cell proliferation is dependent on its interaction with the bone marrow (BM) microenvironment. AML associated mesenchymal stem cells (AML-MSCs) supported the proliferation of leukaemia cells and contributed to disease progression. Stromal microenvironment promoted a metabolic switch but precise underlying molecular mechanisms are poorly understood. Previous studies have demonstrated transfer of functional mitochondria from AML-MSCs to AML blasts facilitatin

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Bonnet, Dominique. "Normal and leukaemic stem cells." British Journal of Haematology 130, no. 4 (2005): 469–79. http://dx.doi.org/10.1111/j.1365-2141.2005.05596.x.

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Brown, Geoffrey, Lucía Sánchez, and Isidro Sánchez-García. "Are Leukaemic Stem Cells Restricted to a Single Cell Lineage?" International Journal of Molecular Sciences 21, no. 1 (2019): 45. http://dx.doi.org/10.3390/ijms21010045.

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Cancer-stem-cell theory states that most, if not all, cancers arise from a stem/uncommitted cell. This theory revolutionised our view to reflect that cancer consists of a hierarchy of cells that mimic normal cell development. Elegant studies of twins who both developed acute lymphoblastic leukaemia in childhood revealed that at least two genomic insults are required for cancer to develop. These ‘hits’ do not appear to confer a growth advantage to cancer cells, nor do cancer cells appear to be better equipped to survive than normal cells. Cancer cells created by investigators by introducing spe

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Bonnet, D. "Cancer stem cells: AMLs show the way." Biochemical Society Transactions 33, no. 6 (2005): 1531–33. http://dx.doi.org/10.1042/bst0331531.

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The blood-related cancer leukaemia was the first disease where human CSCs (cancer stem cells), or LSCs (leukaemic stem cells), were isolated. The haematopoietic system is one of the best tissues for investigating CSCs, since the developmental hierarchy of normal blood formation is well defined. Leukaemia can now be viewed as aberrant haematopoietic processes initiated by rare LSCs that have maintained or reacquired the capacity for indefinite proliferation through accumulated mutations and/or epigenetic changes. Yet, despite their critical importance, much remains to be learned about the devel

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Kuek, Vincent, Anastasia M. Hughes, Rishi S. Kotecha, and Laurence C. Cheung. "Therapeutic Targeting of the Leukaemia Microenvironment." International Journal of Molecular Sciences 22, no. 13 (2021): 6888. http://dx.doi.org/10.3390/ijms22136888.

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In recent decades, the conduct of uniform prospective clinical trials has led to improved remission rates and survival for patients with acute myeloid leukaemia and acute lymphoblastic leukaemia. However, high-risk patients continue to have inferior outcomes, where chemoresistance and relapse are common due to the survival mechanisms utilised by leukaemic cells. One such mechanism is through hijacking of the bone marrow microenvironment, where healthy haematopoietic machinery is transformed or remodelled into a hiding ground or “sanctuary” where leukaemic cells can escape chemotherapy-induced

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Shlush, Liran I., Sasan Zandi, Amanda Mitchell, et al. "Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia." Nature 506, no. 7488 (2014): 328–33. http://dx.doi.org/10.1038/nature13038.

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Dissertations / Theses on the topic "Leukaemic Stem Cells"

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Lewis, Ian D. "Characterisation of normal and leukaemic stem cells in chronic myeloid leukaemia /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phl6745.pdf.

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POTETI, MARTINA. "The metabolic profile of Chronic Myeloid Leukaemia: stem cells as a target to overcome resistance to therapy." Doctoral thesis, Università di Siena, 2019. http://hdl.handle.net/11365/1071850.

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Chronic Myeloid Leukaemia (CML) is a stem cell-driven disorder treated with Tyrosine Kinase inhibitors (TKi) with impressive efficacy. However, TKi are unable in most cases to prevent the relapse of disease, as even a very successful response to treatment results in the persistence of a state of Minimal Residual Disease (MRD). Our hypothesis predicts that MRD is sustained by the persistence of Leukaemic Stem Cells (LSC) capable to survive and cycle independently of BCR/Abl kinase activity within Bone Marrow (BM) stem cell niches where severe oxygen and glucose shortage would result in BCR/Ablp

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Volpe, Giacomo. "Regulation of flt3 gene expression in haematopoietic and leukaemic stem cells." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/822/.

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The interaction between the tyrosine kinase receptor Flt3 and its ligand leads to signalling during the commitment of haematopoietic stem cells (HSCs). Constitutive activation of the Flt3/FL pathway is a key factor in enhanced survival and expansion in acute myeloid leukaemia (AML). Although there is extensive knowledge regarding mutations leading to the constitutive activation of Flt3 receptor activity, the molecular mechanisms underlying the regulation of the \(flt3\) gene in HSCs, and how such mechanisms might be altered in leukaemia, are still poorly understood. Here, by using HSC and leuk

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Kuntz, Elodie Marie. "An investigation of metabolic vulnerabilities in chronic myeloid leukaemic stem cells." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8615/.

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Chronic myeloid leukaemia (CML) is a myeloproliferative disorder that originates at the haematopoietic stem cell (HSC) level. CML is driven by BCR-ABL, a fusion oncoprotein with a constitutive tyrosine kinase activity. The discovery of imatinib, a c-Abl specific tyrosine kinase inhibitor (TKI), revolutionised the treatment of CML by inducing cytogenetic and molecular responses in the majority of CML patients in chronic phase. However, imatinib and second/third generation TKIs do not eradicate leukaemic stem cells (LSCs), leading to disease persistence with associated risk of toxicity, drug res

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Robinson, Simon N. "Proliferation regulation of haematopoietic stem cells in normal and leukaemic haematopoiesis." Thesis, University of St Andrews, 1992. http://hdl.handle.net/10023/14965.

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The cellular integrity of the blood is maintained by the cellular output of the haematopoietic stem cell population which produces the specialized precursors and differentiated cells which constitute the blood. The investigation of haematopoietic stem cell behaviour and regulation has been hampered by both the difficulty in their identification and the development of relevant assay systems. The purpose of this investigation was to study the behaviour and regulation of the haematopoietic stem cell population in normal and leukaemic haematopoiesis using an in vitro assay of a primitive haematopo

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江卓庭 and Cheuk-ting Kong. "Understanding the function of the Mll-een leukaemic fusion gene by embryonic stem cell approaches." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31244312.

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Taylor, Alan. "The role of leukaemia inhibitory factor and a leukaemic associated inhibitor in the control of the proliferation of haematopoietic stem cells." Thesis, University of St Andrews, 1996. http://hdl.handle.net/10023/14962.

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Activities associated with, or interacting with, leukaemic cell populations were assayed for the ability to influence in vitro haematopoiesis. The first of these, the glycoprotein leukaemia inhibitory factor (LIF), has a role in aspects of murine, non human primate and human haematopoiesis. It is thought to be particularly important in the development of megakaryocytes and is also known to induce the terminal differentiation of certain leukaemic cell lines. LIF was assayed both for direct and indirect effects on the proliferation of haematopoietic precursor cell populations in vitro. As a dire

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Austin, Pamela M. "Defining biological properties of the leukaemic stem cell in Hoxa9Meis1-induced leukaemia." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=80222.

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A subset of the leukaemic clone, the leukaemic stem cell (L-HSC), is responsible for the maintenance and propagation of a leukaemia. Most current therapies, however, do not target this population. In this thesis, I show that a determinant of disease phenotype is the frequency of the leukaemic stem cell within the leukaemic population. Moreover, the frequency of L-HSC in a leukaemia is predetermined by the inherent properties of the cell that is transformed and can be attributed to the ontogenic origin of the cell. Ideal therapies would specifically target mechanistic defects in leukaemi

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Carlens, Stefan. "Leukaemic relapse after allogeneic haematopoietic stem cell transplantation and the use of the graft-versus-leukaemia effect /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4310-9/.

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Taussig, David. "Characterisation of acute myeloid leukaemia stem cells." Thesis, Queen Mary, University of London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424766.

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Books on the topic "Leukaemic Stem Cells"

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M, Carella Angelo, ed. Chronic myeloid leukaemia: Biology and treatment. Martin Dunitz, 2001.

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Collins, Graham, and Chris Bunch. Acute leukaemia. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0286.

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Acute leukaemias are rapidly progressive, clonal haematopoietic stem cell disorders resulting in the accumulation of immature blood cell precursors (known as blasts) in the bone marrow. There are two main types, defined by the presence of myeloid lineage or lymphoid markers on the blast cells: acute myeloid leukaemia and acute lymphoblastic leukaemia. This chapter addresses the causes, diagnosis, and management of the acute leukaemias.

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Bunch, Chris. Chronic leukaemia. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0287.

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In the chronic leukaemias, leukaemogenesis occurs in two different cell types (and possibly even two different anatomical sites), leading to two very different forms of the disease: chronic myeloid leukaemia and chronic lymphocytic leukaemia. Chronic myeloid leukaemia is best thought of as a myeloproliferative disorder. It is a clonal disorder of the haematopoietic stem cell, leading to overproduction of the myeloid cells: neutrophils and their precursors, basophils and eosinophils. By contrast, chronic lymphocytic leukaemia can be viewed as a low-grade lymphoma. It is a clonal disorder of mat

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McCann, Shaun R. Radiation and transplantation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198717607.003.0006.

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There is a paradoxical relationship between ionizing radiation and leukaemia. On the one hand, it is known that exposure to high doses of ionizing radiation causes leukaemia; on the other hand, the preparative regimens for stem cell transplantation, which can cure leukaemia, often contain total body irradiation. This chapter discusses the effect war has had on medical technology, with specific regard to the use of stem cells for the treatment of blood disorders such as leukaemia and sickle cell anaemia. The transfer of laboratory techniques to the clinical practice of stem cell transfer and bo

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Ajithkumar, Thankamma, Ann Barrett, Helen Hatcher, and Natalie Cook. Paediatric malignancies. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235636.003.0015.

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Leukaemia is the commonest cancer (accounting for >40% of cases) in children. It is a clonal proliferation of stem cells which leads to bone marrow failure and tissue infiltration.• Acute lymphoblastic leukaemia (ALL): 4/100,000• Acute myeloid leukaemia (AML): 0.7/100,000• Chronic myeloid leukaemia (CML): 0.2/100,000...

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McCann, Shaun R. Leukaemia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198717607.003.0007.

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The word leukaemia still is associated with foreboding and a fear of premature death. Steady advances have been made in the treatment of childhood leukaemia but, with notable exceptions, the same is not true in adults. The so-called genetic/molecular revolution has extended the understanding of the pathogenesis of many forms of leukaemia but, as yet, has rarely facilitated cure. With the introduction of tyrosine kinase inhibitor therapy, chronic myeloid leukaemia is the obvious exception but it still needs to be seen as to whether the cytogenetic/molecular revolution can provide cures for many

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Goldman, John M., Angelo M. Carella, George Q. Daley, Connie J. Eaves, and Hehlmann Rudiger. Chronic Myeloid Leukaemia: Biology and Treatment. Taylor & Francis Group, 2003.

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Bunch, Chris. Myelodysplasia. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0288.

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The myelodysplastic syndromes (or myelodysplasias) comprise a spectrum of disorders characterized by dysplastic or ineffective haemopoiesis that leads to variable anaemia, neutropenia, and thrombocytopenia. There is often a degree of red-cell macrocytosis. The majority are clonal stem cell disorders in which the abnormal clone predominates and expands only slowly over a number of years. Myelodysplasias have a tendency to develop ultimately into acute leukaemia in some patients; for this reason, they are sometimes referred to as ‘preleukaemias’, even though two-thirds of patients will never dev

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Book chapters on the topic "Leukaemic Stem Cells"

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Marks, David I. "Allogeneic Stem Cell Transplantation for Acute Lymphoblastic Leukaemia in Adults." In Allogeneic Stem Cell Transplantation. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-478-0_13.

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Berger, Marc G., and Céline Bourgne. "Contribution of Chronic Myeloid Leukaemia (CML) as a Disease Model to Define and Study Clonal Heterogeneity." In Stem Cells Heterogeneity in Cancer. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-14366-4_10.

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Goldstone, A. H., A. R. Perry, L. G. Robinson, K. Wheatley, and A. K. Burnett. "Stem Cell Transplants in Acute Myeloid Leukaemia (AML)." In Haematology and Blood Transfusion / Hämatologie und Bluttransfusion. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-71960-8_126.

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Geißler, K., W. Hinterberger, P. Bettelheim, P. Höcker, M. Fischer, and K. Lechner. "Circulating Stem Cells in Patients with Akute Leukaemia in Remission." In 11th Annual meeting of the EBMT. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-662-40457-7_35.

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Viale, Andrea, and Pier Giuseppe Pelicci. "Regulation of Self-Renewing Divisions in Normal and Leukaemia Stem Cells." In Cell Cycle Deregulation in Cancer. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1770-6_7.

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Rehmann-Sutter, Christoph, Martina Jürgensen, Madeleine Herzog, and Christina Schües. "Open Questions." In Philosophy and Medicine. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-04166-2_16.

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AbstractThe families we approached have two exceptional things in common: they all experienced the dramatic event of a life-threatening disease such as leukaemia affecting one of their children; and, in all of these families, that child was treated with a stem cell transplant taken from a sibling’s body. In this last chapter of the book we reflect very briefly on our interview experiences, analysis, and discussions. In the end, we identify open questions and further areas which may invite further research.

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Marks, David I. "Allogeneic Stem Cell Transplantation for Acute Lymphoblastic Leukaemia in Adults." In Adult Acute Lymphocytic Leukemia. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-707-5_18.

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Green, A. R. "The Stem Cell Leukaemia Gene: A Critical Regulator of Haemopoiesis Vasculogenesis." In Haematology and Blood Transfusion Hämatologie und Bluttransfusion. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-59358-1_21.

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Blaise, Didier, and Sabine Fürst. "Post-CAR-T Cell Therapy (Consolidation and Relapse): Lymphoma." In The EBMT/EHA CAR-T Cell Handbook. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_33.

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AbstractEven after a decade of use, CAR-T cell therapy for non-Hodgkin lymphoma (NHL) is still evolving, and disease control is now the main concern in the majority of experienced centres. Indeed, despite highly appealing objective response (OR) rates in refractory patients, the long-term overall survival (OS) of this population has only slightly improved. Pivotal studies have suggested that 2-year OS rates do not surpass 30%, even though results improve when complete response (CR) is achieved within the first 3 months after treatment (Wang et al. 2020; Schuster et al. 2019; Neelapu et al. 2017). Although achieving this exceptionally high level of OR is praiseworthy, similar improvements have not been made regarding OS, and current OS probabilities are not satisfactory. Of course, there are multiple reasons for this; a substantial proportion of patients either do not achieve an initial response or experience progression very soon after treatment, with poor OS (Chow et al. 2019). Both populations present with disease burden or aggressive cancer prior to CAR-T cell therapy, possibly having been referred too late in the course of treatment or waited too long before CAR-T cells were processed for them. Both of these issues have potential solutions, such as more widely publicizing the efficacy of CAR-T cells, which may increase referrals at an earlier stage, and developing methods, which are already being heavily investigated, for shortening the manufacturing process (Rafiq et al. 2020). In the latter case, the use of allogeneic lymphocytes could allow for already prepared cells to be readily used when needed and would most likely be the most efficient strategy as long as the risk of graft-versus host disease is offset (Graham and Jozwik 2018). Thus, achieving CR is a crucial step in increasing OS, as patients with partial response (PR) or stable disease (SD) present with lower OS, while currently, recurrence appears to be rare when CR is maintained for more than 6 months (Komanduri 2021). However, the disease will likely recur in more than half of patients in the months following treatment, possibly due to issues such as the poor persistence of CAR-T cells (which may not be as crucial as once thought for acute lymphoblastic leukaemia (Komanduri 2021)) or the loss of target antigen expression (which has been regularly documented (Rafiq et al. 2020)). Both of these mechanisms could potentially be used to develop methods that reduce recurrence after CAR-T cell therapy. In fact, the most popular approaches currently being investigated are attempting to either use two CAR-T cell types that each target different antigens or to create CAR-T cell constructs that target either multiple antigens or an antigen other than CD19 (Shah et al. 2020). The concomitant infusion of CAR-T cells with targeted therapies is also being explored in other B-cell malignancies and appears to both increase the CR rate and decrease recurrence (Gauthier et al. 2020). When recurrence does occur, patient OS is rather dismal, and the best remaining option would most likely be inclusion in a clinical trial. If this option is not available, salvage therapy may be attempted, although cytotoxic treatments are extremely limited given that most diseases have been refractory to numerous lines of treatment prior to immunotherapy. A few case reports and studies with a small patient population receiving anti-PD-1 antibodies, ibrutinib, or ImiDs have been reported with largely anecdotal supporting evidence (Byrne et al. 2019). However, even in the case of a new objective response (OR), the subsequent risk of recurrence is substantial and may invite further consolidation with allogeneic haematopoietic stem cell transplantation (Byrne et al. 2019), which has already been performed in patients treated for acute lymphoblastic leukaemia (Hay et al. 2019). However, the efficacy of this strategy remains to be validated in NHL patients in clinical trials. Further supporting evidence, although limited, has recently been reported concerning an additional treatment with CAR-T cells inducing an OR. Of the 21 NHL patients included in the study, the OR rate after the second infusion was 52% (CR, n = 4; PR, n = 7), with some durable responses inviting further investigations (Gauthier et al. 2021). Overall, with such poor outcomes after recurrence, current efforts are also focused on predicting the patients most likely to experience disease progression and that are potential candidates for preemptive consolidation therapy, although there is no doubt that patients who do not achieve a rapid CR should be the first candidates. Additionally, immune monitoring should encompass not only CAR-T cell survival but also the detection of circulating tumour DNA (Komanduri 2021) because this could aid in detecting subclinical recurrence and in deciding whether consolidation or maintenance therapy should be administered. However, currently, all these approaches are highly speculative and require further clinical study.

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Rehmann-Sutter, Christoph, and Christina Schües. "A Donor by Coincidence or by Conception – My Sister’s Keeper Revisited." In Philosophy and Medicine. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-04166-2_2.

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AbstractThirteen-year-old Anna Fitzgerald has been conceived in order to be a matching donor for her older sister Kate, who has a rare form of leukaemia. The story in the novel “My Sister’s Keeper” by Jody Picoult, and Nick Cassavetes’ movie, has many striking similarities to the situations that we heard from the families we studied – despite one significant difference: Anna is created to be a saviour sibling, whereas the stem cell donors we interviewed already existed and were found to be matching. We discuss the film as an emotionally complex, multi-layered narrative that gives insight into the perspectives of different family members and into some key aspects of a paradigmatic family conflict. The temporal order of the film’s story-telling using multiple flash-backs and retakes represents the entangled temporalities of experience and memory.

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Conference papers on the topic "Leukaemic Stem Cells"

1

Rovida, E., I. Tusa, G. Cheloni, et al. "PO-145 ERK5 pathway inhibitors inhibit the maintenance of chronic myeloid leukaemia stem cells." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.186.

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Elster, Doris, and Julia Holzer. "PROMOTION OF HEALTH LITERACY IN THE CONTEXT OF STEM CELL DONATION FOR LEUKAEMIA PATIENTS." In 15th annual International Conference of Education, Research and Innovation. IATED, 2022. http://dx.doi.org/10.21125/iceri.2022.1790.

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Osorio, F., A. Rosendahl Huber, F. Camargo, and R. Van Boxtel. "30 Whole-genome sequencing of normal stem cells provides novel insights into human native hematopoiesis and leukaemia aetiology." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.30.

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Park, ES, YJ Chung, and PD Aplan. "PO-020 Discrepancy in efficacy of disulfiram between NUP98-PHF23 fusion acute myelogenous leukaemia cell line andin vivomouse model: sharing normal hematopoietic stem cells niche." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.555.

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Holzer, Julia, and Doris Elster. "INVESTIGATING PREDICTORS OF ADOLESCENTS’ INTENTION TO DONATE STEM CELLS TO LEUKAEMIA PATIENTS: A STUDY BASED ON THE THEORY OF PLANNED BEHAVIOUR." In 14th International Conference on Education and New Learning Technologies. IATED, 2022. http://dx.doi.org/10.21125/edulearn.2022.1107.

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Bandeira, Deborah, Mariana Rietmann da Cunha Madeira, Marianne Borges Landau, and Andréa Rodrigues Cordovil Pires. "2022-RA-1062-ESGO Uterine granulocytic sarcoma as an extra-medullary relapse of acute myeloid leukaemia in an allogeneic hematopoietic stem cell transplantation recipient." In ESGO 2022 Congress. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-esgo.430.

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