Journal articles on the topic 'Leukaemia, Stem cells, Hypoxia, HIF'
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Gezer, Deniz, Amelie V. Guitart, Milica Vukovic, Chithra Subramani, Karen Dunn, Patrick Pollard, Peter J. Ratcliffe, Tessa L. Holyoake, and Kamil Kranc. "HIF-1α Is Not Essential For The Establishment Of MLL-Leukaemic Stem Cells." Blood 122, no. 21 (November 15, 2013): 3767. http://dx.doi.org/10.1182/blood.v122.21.3767.3767.
Full textTomita, Mariko, Gregg L. Semenza, Canine Michiels, Takehiro Matsuda, Jun-Nosuke Uchihara, Taeko Okudaira, Yuetsu Tanaka, Naoya Taira, Kazuiku Ohshiro, and Naoki Mori. "Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells." Biochemical Journal 406, no. 2 (August 13, 2007): 317–23. http://dx.doi.org/10.1042/bj20070286.
Full textChoi, Jong Ho, Yun Bin Lee, Jieun Jung, Seong Gyu Hwang, IL-Hoan Oh, and Gi Jin Kim. "Hypoxia Inducible Factor-1αRegulates the Migration of Bone Marrow Mesenchymal Stem Cells via Integrinα4." Stem Cells International 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/7932185.
Full textBernard, Olivier, Florence Jeny, Yurdagül Uzunhan, Elisabetta Dondi, Rahma Terfous, Rabab Label, Angela Sutton, et al. "Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signaling." American Journal of Physiology-Lung Cellular and Molecular Physiology 314, no. 3 (March 1, 2018): L360—L371. http://dx.doi.org/10.1152/ajplung.00153.2017.
Full textEliasson, Pernilla M., and Jan-Ingvar Jönsson. "A Hypoxic Niche in the Mouse Bone Marrow Diminishes Proliferation and Differentiation of Hematopoietic Stem Cells." Blood 112, no. 11 (November 16, 2008): 4777. http://dx.doi.org/10.1182/blood.v112.11.4777.4777.
Full textHu, Cheng-Jun, Sangeeta Iyer, Aneesa Sataur, Kelly L. Covello, Lewis A. Chodosh, and M. Celeste Simon. "Differential Regulation of the Transcriptional Activities of Hypoxia-Inducible Factor 1 Alpha (HIF-1α) and HIF-2α in Stem Cells." Molecular and Cellular Biology 26, no. 9 (May 1, 2006): 3514–26. http://dx.doi.org/10.1128/mcb.26.9.3514-3526.2006.
Full textTang, Di, Junhui Zhang, Tiantian Yan, Jingyu Wei, Xupin Jiang, Dongxia Zhang, Qiong Zhang, Jiezhi Jia, and Yuesheng Huang. "FG-4592 Accelerates Cutaneous Wound Healing by Epidermal Stem Cell Activation via HIF-1α Stabilization." Cellular Physiology and Biochemistry 46, no. 6 (2018): 2460–70. http://dx.doi.org/10.1159/000489652.
Full textChang, Yao-Lung, Shuenn-Dyh Chang, An-Shine Chao, Martin Sieber, Chia-Lung Tsai, and Po-Jen Cheng. "Effect of Hypoxia on Glucose Transporter 1 and 3 Gene Expression in Placental Mesenchymal Stem Cells Derived from Growth-Restricted Fetuses." Genes 13, no. 5 (April 25, 2022): 752. http://dx.doi.org/10.3390/genes13050752.
Full textChang, Yao-Lung, Shuenn-Dyh Chang, An-Shine Chao, Martin Sieber, Chia-Lung Tsai, and Po-Jen Cheng. "Effect of Hypoxia on Glucose Transporter 1 and 3 Gene Expression in Placental Mesenchymal Stem Cells Derived from Growth-Restricted Fetuses." Genes 13, no. 5 (April 25, 2022): 752. http://dx.doi.org/10.3390/genes13050752.
Full textCarcelén, María, Carlos Velásquez, Veronica Vidal, Olga Gutierrez, and Jose L. Fernandez-Luna. "HIF2α Upregulates the Migration Factor ODZ1 under Hypoxia in Glioblastoma Stem Cells." International Journal of Molecular Sciences 23, no. 2 (January 11, 2022): 741. http://dx.doi.org/10.3390/ijms23020741.
Full textYoshida, Kozue, Keita Kirito, Kenneth Kaushansky, and Norio Komatsu. "Thrombopoietin (TPO) Regulates HIF-1α Level through Generation of Mitochondrial Reactive Oxygen Species (ROS)." Blood 106, no. 11 (November 16, 2005): 3145. http://dx.doi.org/10.1182/blood.v106.11.3145.3145.
Full textPapale, Marco, Mariachiara Buccarelli, Cristiana Mollinari, Matteo A. Russo, Roberto Pallini, Lucia Ricci-Vitiani, and Marco Tafani. "Hypoxia, Inflammation and Necrosis as Determinants of Glioblastoma Cancer Stem Cells Progression." International Journal of Molecular Sciences 21, no. 8 (April 11, 2020): 2660. http://dx.doi.org/10.3390/ijms21082660.
Full textYang, Jinfu, Tao Tang, Feng Li, Wenwu Zhou, Jian Liu, Zhiping Tan, Wei Zheng, Yifeng Yang, Xinmin Zhou, and Jianguo Hu. "Experimental Study of the Effects of Marrow Mesenchymal Stem Cells Transfected with Hypoxia-Inducible Factor-1αGene." Journal of Biomedicine and Biotechnology 2009 (2009): 1–10. http://dx.doi.org/10.1155/2009/128627.
Full textKučera, Jan, Julie Netušilová, Stanislava Sladeček, Martina Lánová, Ondřej Vašíček, Kateřina Štefková, Jarmila Navrátilová, Lukáš Kubala, and Jiří Pacherník. "Hypoxia Downregulates MAPK/ERK but Not STAT3 Signaling in ROS-Dependent and HIF-1-Independent Manners in Mouse Embryonic Stem Cells." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–16. http://dx.doi.org/10.1155/2017/4386947.
Full textHofmann, Nicole A., Anna Ortner, Rodrigo Jacamo, Andreas Reinisch, Katharina Schallmoser, Rokhsareh Rohban, Margareta Frühwirth, et al. "A Novel Role for Mesenchymal Stem/Progenitor Cells As Hypoxia Sensors During Initiation of Neo-Vasculogenesis in Vivo." Blood 120, no. 21 (November 16, 2012): 613. http://dx.doi.org/10.1182/blood.v120.21.613.613.
Full textMenon, Alessandra, Pasquale Creo, Marco Piccoli, Sonia Bergante, Erika Conforti, Giuseppe Banfi, Pietro Randelli, and Luigi Anastasia. "Chemical Activation of the Hypoxia-Inducible Factor Reversibly Reduces Tendon Stem Cell Proliferation, Inhibits Their Differentiation, and Maintains Cell Undifferentiation." Stem Cells International 2018 (2018): 1–13. http://dx.doi.org/10.1155/2018/9468085.
Full textHu, Cheng-Jun, Li-Yi Wang, Lewis A. Chodosh, Brian Keith, and M. Celeste Simon. "Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation." Molecular and Cellular Biology 23, no. 24 (December 15, 2003): 9361–74. http://dx.doi.org/10.1128/mcb.23.24.9361-9374.2003.
Full textZhang, Lei, Hai-Yan Wang, Mu-Qiong Li, Xi-Xi Wang, Li Fan, and Yu-Sheng Wang. "A Trojan horse biomimetic delivery system using mesenchymal stem cells for HIF-1α siRNA-loaded nanoparticles on retinal pigment epithelial cells under hypoxia environment." International Journal of Ophthalmology 15, no. 11 (November 18, 2022): 1743–51. http://dx.doi.org/10.18240/ijo.2022.11.03.
Full textSuda, Toshio. "Metabolic Regulation of Hematopoietic Stem Cells During Stress." Blood 120, no. 21 (November 16, 2012): SCI—42—SCI—42. http://dx.doi.org/10.1182/blood.v120.21.sci-42.sci-42.
Full textZhang, Huimin, Haiquan Lu, Lisha Xiang, John W. Bullen, Chuanzhao Zhang, Debangshu Samanta, Daniele M. Gilkes, Jianjun He, and Gregg L. Semenza. "HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells." Proceedings of the National Academy of Sciences 112, no. 45 (October 28, 2015): E6215—E6223. http://dx.doi.org/10.1073/pnas.1520032112.
Full textZhang, Chuanzhao, Debangshu Samanta, Haiquan Lu, John W. Bullen, Huimin Zhang, Ivan Chen, Xiaoshun He, and Gregg L. Semenza. "Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA." Proceedings of the National Academy of Sciences 113, no. 14 (March 21, 2016): E2047—E2056. http://dx.doi.org/10.1073/pnas.1602883113.
Full textAbaci, Hasan Erbil, Rachel Truitt, Eli Luong, German Drazer, and Sharon Gerecht. "Adaptation to oxygen deprivation in cultures of human pluripotent stem cells, endothelial progenitor cells, and umbilical vein endothelial cells." American Journal of Physiology-Cell Physiology 298, no. 6 (June 2010): C1527—C1537. http://dx.doi.org/10.1152/ajpcell.00484.2009.
Full textXu, Na, Yajuan Xiao, Xuan Zhou, Lin Li, Fen Huang, Bing Xu, and Liu Xiaoli. "Inhibition of Siah2 Ubiquitin Ligase By Vitamin K3 Attenuates Hypoxia and Blocks K562-R Cells Resistance." Blood 124, no. 21 (December 6, 2014): 5214. http://dx.doi.org/10.1182/blood.v124.21.5214.5214.
Full textHeirani-Tabasi, Asieh, Shirin Hamedakbari Toosi, Mahdi Mirahmadi, and Mahmood Raeesolmohaddeseen. "Hypoxia-based Stem/Progenitor Cell Therapy: Focus on CXCR4/SDF-1 Axis." Journal of Genes and Cells 3 (October 10, 2017): 64. http://dx.doi.org/10.15562/gnc.59.
Full textAjdukovic, J. "HIF-1 — A BIG CHAPTER IN THE CANCER TALE." Experimental Oncology 38, no. 1 (March 22, 2016): 9–12. http://dx.doi.org/10.31768/2312-8852.2016.38(1):9-12.
Full textWozny, Anne-Sophie, Arnaud Gauthier, Gersende Alphonse, Céline Malésys, Virginie Varoclier, Michael Beuve, Delphine Brichart-Vernos, et al. "Involvement of HIF-1α in the Detection, Signaling, and Repair of DNA Double-Strand Breaks after Photon and Carbon-Ion Irradiation." Cancers 13, no. 15 (July 30, 2021): 3833. http://dx.doi.org/10.3390/cancers13153833.
Full textZhuo, Yi, Lei Wang, Lite Ge, Xuan Li, Da Duan, Xiaohua Teng, Miao Jiang, et al. "Hypoxic Culture Promotes Dopaminergic-Neuronal Differentiation of Nasal Olfactory Mucosa Mesenchymal Stem Cells via Upregulation of Hypoxia-Inducible Factor-1α." Cell Transplantation 26, no. 8 (August 2017): 1452–61. http://dx.doi.org/10.1177/0963689717720291.
Full textCui, Chun-Ping, Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Daniel Wai-Hung Ho, Eunice Yuen-Ting Lau, Yu-Man Tsui, Lo-Kong Chan, et al. "SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop." Gut 66, no. 12 (March 3, 2017): 2149–59. http://dx.doi.org/10.1136/gutjnl-2016-313264.
Full textCowden Dahl, Karen D., Sarah E. Robertson, Valerie M. Weaver, and M. Celeste Simon. "Hypoxia-inducible Factor Regulates αvβ3 Integrin Cell Surface Expression." Molecular Biology of the Cell 16, no. 4 (April 2005): 1901–12. http://dx.doi.org/10.1091/mbc.e04-12-1082.
Full textChilov, D., G. Camenisch, I. Kvietikova, U. Ziegler, M. Gassmann, and R. H. Wenger. "Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha." Journal of Cell Science 112, no. 8 (April 15, 1999): 1203–12. http://dx.doi.org/10.1242/jcs.112.8.1203.
Full textRoitbak, Tamara, Lu Li, and Lee Anna Cunningham. "Neural Stem/Progenitor Cells Promote Endothelial Cell Morphogenesis and Protect Endothelial Cells against Ischemia via HIF-1α-Regulated VEGF Signaling." Journal of Cerebral Blood Flow & Metabolism 28, no. 9 (May 14, 2008): 1530–42. http://dx.doi.org/10.1038/jcbfm.2008.38.
Full textJunsheng, Mu, Tian Kun, Zhou Fan, and Bo Ping. "Myocardial Patch Formation by Three-Dimensional Culture of Bone Marrow Mesenchymal Stem Cells with 3-Hydroxybutyrate-Co-4-Hydroxybutyrate Under Hypoxia." Journal of Biomaterials and Tissue Engineering 10, no. 7 (July 1, 2020): 922–29. http://dx.doi.org/10.1166/jbt.2020.2353.
Full textNishikawa, Masahiro, Akihiro Inoue, Yoshihiro Ohtsuka, Saya Ozaki, Shirabe Matsumoto, Satoshi Suehiro, Hajime Yano, et al. "CBMS-04 SIGNIFICANT ROLE OF HYPOXIA IN THE EXPRESSION AND FUNCTION OF OSTEOPONTIN IN CD44-HIGHLY EXPRESSED GLIOMA STEM-LIKE CELLS IN TUMOR PROGRESSION OF GLIOBLASTOMA." Neuro-Oncology Advances 1, Supplement_2 (December 2019): ii5. http://dx.doi.org/10.1093/noajnl/vdz039.024.
Full textWei, Lingling, Lijie Zhang, Longyan Yang, Xin Wang, Chunhua Zhao, and Dong Zhao. "Protective Effect of Mesenchymal Stem Cells on Isolated Islets Survival and Against Hypoxia Associated With the HIF-1α/PFKFB3 Pathway." Cell Transplantation 31 (January 2022): 096368972110731. http://dx.doi.org/10.1177/09636897211073127.
Full textChaparro, Alejandra, Mauricio Lozano, Dominique Gaedechens, Carolina López, Daniela Albers, Marcela Hernández, Andrés Pascual, José Nart, and Carlos E. Irarrazabal. "Exploring the Expression of Pro-Inflammatory and Hypoxia-Related MicroRNA-20a, MicroRNA-30e, and MicroRNA-93 in Periodontitis and Gingival Mesenchymal Stem Cells under Hypoxia." International Journal of Molecular Sciences 23, no. 18 (September 7, 2022): 10310. http://dx.doi.org/10.3390/ijms231810310.
Full textCheloni, Giulia, Michele Tanturli, Ignazia Tusa, Ngoc Ho DeSouza, Yi Shan, Antonella Gozzini, Fréderic Mazurier, Elisabetta Rovida, Shaoguang Li, and Persio Dello Sbarba. "Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine." Blood 130, no. 5 (August 3, 2017): 655–65. http://dx.doi.org/10.1182/blood-2016-10-745588.
Full textTeti, Gabriella, Stefano Focaroli, Viviana Salvatore, Eleonora Mazzotti, Laura Ingra’, Antonio Mazzotti, and Mirella Falconi. "The Hypoxia-Mimetic Agent Cobalt Chloride Differently Affects Human Mesenchymal Stem Cells in Their Chondrogenic Potential." Stem Cells International 2018 (2018): 1–9. http://dx.doi.org/10.1155/2018/3237253.
Full textXu, Na, Xiaozhen Xiao, Yajuan Xiao, Xuan Zhou, Guanlun Gao, Fen Huang, Dan Xu, Hongsheng Zhou, Bing Xu, and Liu Xiaoli. "The E3 Ubiquitin Ligases Siah2 Contributes To Imatinib Resistance In Chronic Myeloid Leukemia In Hypoxia Condition." Blood 122, no. 21 (November 15, 2013): 2530. http://dx.doi.org/10.1182/blood.v122.21.2530.2530.
Full textMartin, Anthony R., Cyril Ronco, Luc Demange, and Rachid Benhida. "Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories." MedChemComm 8, no. 1 (2017): 21–52. http://dx.doi.org/10.1039/c6md00432f.
Full textNiechi, Ignacio, Atenea Uribe-Ojeda, José Ignacio Erices, Ángelo Torres, Daniel Uribe, José Dellis Rocha, Pamela Silva, Hans G. Richter, Rody San Martín, and Claudia Quezada. "Adenosine Depletion as A New Strategy to Decrease Glioblastoma Stem-Like Cells Aggressiveness." Cells 8, no. 11 (October 30, 2019): 1353. http://dx.doi.org/10.3390/cells8111353.
Full textChakraborty, Damayanti, Wei Cui, Gracy X. Rosario, Regan L. Scott, Pramod Dhakal, Stephen J. Renaud, Makoto Tachibana, et al. "HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia." Proceedings of the National Academy of Sciences 113, no. 46 (November 2, 2016): E7212—E7221. http://dx.doi.org/10.1073/pnas.1612626113.
Full textXu, Wei, Ruijun Xu, Zhikun Li, Yi Wang, and Ruixi Hu. "Hypoxia changes chemotaxis behaviour of mesenchymal stem cells via HIF-1α signalling." Journal of Cellular and Molecular Medicine 23, no. 3 (January 9, 2019): 1899–907. http://dx.doi.org/10.1111/jcmm.14091.
Full textKozal, Karolina, and Anna Krześlak. "The Role of Hypoxia-Inducible Factor Isoforms in Breast Cancer and Perspectives on Their Inhibition in Therapy." Cancers 14, no. 18 (September 17, 2022): 4518. http://dx.doi.org/10.3390/cancers14184518.
Full textHan, Myung-Kwan, Charlie Mantel, Ying Guo, Wen Tao, and Hal E. Broxmeyer. "Role of SIRT1 in Proliferation and Self-Renewal of Mouse Embryonic Stem Cells." Blood 106, no. 11 (November 16, 2005): 520. http://dx.doi.org/10.1182/blood.v106.11.520.520.
Full textYu, Qin, Jie Lin, Lizhen Liu, Peipei Li, XiaoBo Xuan, Yan Wang, YanPing Duan, and Hui Dong. "Research of HIF-1 Mediated SDF-1/CXCR4 Axis on the Directional Migration and Neural Differentiation of Mesenchymal Stem Cells." Blood 116, no. 21 (November 19, 2010): 4699. http://dx.doi.org/10.1182/blood.v116.21.4699.4699.
Full textQi, Yanmei, Xiaoxiang Tian, Jie Liu, Yaling Han, Alan M. Graham, M. Celeste Simon, Josef M. Penninger, Peter Carmeliet, and Shaohua Li. "Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis." Journal of Cell Biology 198, no. 1 (July 2, 2012): 103–14. http://dx.doi.org/10.1083/jcb.201111063.
Full textITOH, MAI, YUKI OKUHASHI, YUSUKE TAKAHASHI, YURI SONODA, SALWA MOHAMMAD, TATSUYA SAITO, ERIKA SHIRATORI, and SHUJI TOHDA. "Hypoxia Up-regulates HIF Expression While Suppressing Cell Growth and NOTCH Activity in Leukaemia Cells." Anticancer Research 39, no. 8 (July 31, 2019): 4165–70. http://dx.doi.org/10.21873/anticanres.13575.
Full textForristal, Catherine E., Falak Helwani, Sally Martin, Bianca Nowlan, Ingrid G. Winkler, Andrew Zannettino, and Jean-Pierre Levesque. "Hypoxia Inducible Factor (HIF)-2α Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone Marrow." Blood 122, no. 21 (November 15, 2013): 2895. http://dx.doi.org/10.1182/blood.v122.21.2895.2895.
Full textLee, Sang Hun, Min Hee Kim, and Ho Jae Han. "Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1α." American Journal of Physiology-Cell Physiology 297, no. 1 (July 2009): C207—C216. http://dx.doi.org/10.1152/ajpcell.00579.2008.
Full textLekli, Istvan, Narasimman Gurusamy, Diptarka Ray, Arpad Tosaki, and Dipak K. Das. "Redox regulation of stem cell mobilizationThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research." Canadian Journal of Physiology and Pharmacology 87, no. 12 (December 2009): 989–95. http://dx.doi.org/10.1139/y09-102.
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