Relevant bibliographies by topics / Leptospirosis disease

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Academic literature on the topic 'Leptospirosis disease'

Author: Grafiati
Published: 21 December 2024

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Journal articles on the topic "Leptospirosis disease"

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Charishma Devi, T. V. L., B. Mounika, SK Sharmila, Satheesh S. Gottipati, and P. Srinivas Babu. "A REVIEW ON EPIDEMIOLOGY, PATHOGENESIS AND TREATMENT OF LEPTOSPIROSIS." International Journal of Advanced Research 9, no. 09 (September 30, 2021): 498–504. http://dx.doi.org/10.21474/ijar01/13439.

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Leptospirosis is a zoonotic disease, it arises worldwide but it is most frequent in tropical and subtropical zone. It is one of the notifiable and treatable disease. Leptospirosis is a plague caused by species of bacteria called Leptospira the bacteria shed into the nature via urine of infected animals. Rats are the most recurrent source of human sepsis. Rivers are the assumption to be a predominant risk factor for transmission of disease to humans. It possesses an extensive variation of mechanisms that allow them to avoid the host immune system and cause infection. The infection is extremely vast ranging from subclinical to multi organ infection with elevated mortality. It is frequently mild but can be terminal, it is likely to be serious and the serious alignment form known as Weils disease and can easily steer to death. The mingling of renal failure, hemorrhage and jaundice is known as Weils disease. It is the most affection pattern associated with critical leptospirosis. It is accumulating as a serious problem worldwide and superficially existing as co-infections with various unrelated diseases, including malaria and dengue. Laboratory diagnostic tests are not always accessible and usually diagnosis is executed by enzyme linked immunosorbent assay (ELISA) serology and microscopic agglutination test, rapid test are also feasible. The MAT (microscopic agglutination test) is known as Gold standard. Serological tests are most frequently used for the diagnosis of leptospirois. The carcinogenesis of human disease and mechanism of cell membrane injuries which take place mainly due to the occupancy of leptospirosis along with their antigen in host tissues many molecules hand out to the ability of leptospira to invade, colonize and to adhere. In most of the cases antibiotics are preferred to reduce the symptoms of leptospirosis.
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Chancharoenthana, Wiwat, Asada Leelahavanichkul, Marcus J. Schultz, and Arjen M. Dondorp. "Going Micro in Leptospirosis Kidney Disease." Cells 11, no. 4 (February 16, 2022): 698. http://dx.doi.org/10.3390/cells11040698.

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Leptospirosis is a zoonotic and waterborne disease worldwide. It is a neglected infectious disease caused by Leptospira spp., as well as a reemerging disease and global public health problem with respect to morbidity and mortality both in humans and animals. Leptospirosis emerges as a leading cause of acute febrile illness along with hepatorenal injury in many countries, including Thailand. While most affected persons are symptomatic in acute disease, which is always difficult to differentiate from other tropical diseases, there is growing evidence of subtle manifestations that cause unrecognized chronic symptoms. The kidney is one of the common organs affected by Leptospires. Although acute kidney injury in the spectrum of interstitial nephritis is a well-described characteristic in severe leptospirosis, chronic kidney disease from leptospirosis is widely discussed. Early recognition of severe leptospirosis leads to reduce morbidity and mortality. Thus, in this review, we highlight the spectrum of characteristics involved in leptospirosis kidney disease and the use of serologic and molecular methods, as well as the treatments of severe leptospirosis.
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Yang, C. W., M. S. Wu, and M. J. Pan. "Leptospirosis renal disease." Nephrology Dialysis Transplantation 16, suppl 5 (July 1, 2001): 73–77. http://dx.doi.org/10.1093/ndt/16.suppl_5.73.

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Mulyani, Guntari Titik, Sri Hartati, Hastari Wuryastuty, Ida Tjahajati, Yuriadi Yuriadi, Irkham Widiyono, Yanuartono Yanuartono, et al. "Identifikasi Serovar Penyebab Leptospirosis pada Anjing di Yogyakarta." Jurnal Sain Veteriner 37, no. 2 (December 11, 2019): 227. http://dx.doi.org/10.22146/jsv.39201.

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Leptospirosis is a zoonotic disease of global concern, and is caused by pathogenic serovar Leptospira interrogans. Canine Leptospirososis is widespread worldwide, dogs can act as incidental hosts or maintenance hosts for various serovars. The purpose of this research was to identify leptospire serovars that infect healthy and suspected leptospirosis dogs in Yogyakarta. A total of 56 dogs (36 healthy dogs and 20 suspect leptospirosis dogs) sera were taken from cephalica vein as much as 3 ml. Sera were examined for leptospirosis with Microscopic Aglutination Test (MAT) which conducted at the Research Center for Veterinary Science, Bogor. Microscopic Aglutination Test carried out on various Leptospire serovar, namely: Ichterohaemorrhagiae, Javanica, Celledoni, Ballum, Pyogenes, Cynopeteri, Rachmati, Australis, Pomona, Canicola, Grippotyphosa, Bataviae, Hardjo, and Tarrasovi. The results showed that Celledoni serovars infected 25% of healthy dogs and 5% of suspect leptospirosis dogs, Javanica serovar infected 19% of healthy dogs, Bataviae serovars infected 15% of suspect leptospirosis dogs, Grippotyphosa serovar infected 11% of healthy dogs, Tarrasovi serovar infected 10% of suspect leptospirosis dogs, serovars Cynopteri infects 5% of healthy dogs and 5% of suspect leptospirosis dogs, serovar Pyrogenes infects 5% of healthy dogs and 5% of suspect leptospirosis dogs, and serovar Rachmati infects 5% of suspect leptospirosis dogs. Seven healthy dogs (19%) and 2 suspect leptospirosis dogs (10%) were infected with more than 2 leptospire serovars. From the results of this study it can be concluded that Celledoni serovar of Leptospira interrogans infection causes subclinical leptospirosis, while Bataviae serovar infection causes clinical leptospirosis in dogs in Yogyakarta.
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P, Pati. "Leptospirosis One of the Risk Factor for Kidney Diseases." Open Access Journal of Urology & Nephrology 8, no. 1 (January 13, 2023): 1–4. http://dx.doi.org/10.23880/oajun-16000223.

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The disease leptospirosis is threatening both animals and humans. Leptospirosis can cause complications in multiple organs, including the kidneys early on, most often manifesting as tubulo-interstitial nephritis and tubular dysfunction. More than a million people are infected with leptospirosis every year, making it the most widespread zoonosis. Hotspots of leptospirosis and CKD are the agricultural intensive areas that are prone to flooding. Pallabi Pati Senior Research Fellow(SRF) Molecular Biology Division Regional Medical Research Centre(ICMR),Bhubaneswar. Lack of prompt treatment for acute leptospirosis can lead to chronic kidney damage and ultimately kidney failure. Because of the insidious nature for progression of CKD, the germs that cause it may be present in the kidney without causing any symptoms. Tubulointerstitial nephritis, interstitial fibrosis, and tubular atrophy are histologic findings of leptospirosis renal disease. Leptospirosis in adult male workers is associated with proximal tubule dysfunction, hypokalemia, and chronic kidney disease (CKD).
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Kozishkurt, E., K. Talalaev, O. Melnik, O. Sovirda, E. Gerasimenko, and L. Kostolonova. "Рredicting epizootic risks of leptospirosis." Journal of Education, Health and Sport 12, no. 2 (February 28, 2022): 351–59. http://dx.doi.org/10.12775/jehs.2022.12.02.036.

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Leptospirosis is an infectious disease of humans and animals that is caused by pathogenic spirochetes of the genus Leptospira. It is considered the most common zoonosis in the world and is associated with settings of poor sanitation and agricultural occupations involving contact with animals or water. The authors have analyzed the present day world and particular Ukrainian situation with leptospirorsis and pointed out the urgent measures which could prevent its prevalence.
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Boertjes, Emma, Stefanie Hillebrand, Janneke Elisabeth Bins, and Laurien Oswald. "Pulmonary haemorrhage in Weil’s disease." BMJ Case Reports 13, no. 1 (January 2020): e227570. http://dx.doi.org/10.1136/bcr-2018-227570.

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Leptospirosisis a zoonosis caused by spirochaetes from the species Leptospira. The more severe form of leptospirosis, known as Weil’s disease, is characterised by the triad of jaundice, renal impairment and haemorrhages. Pulmonary involvement occurs in 20%–70% of the patients, with severity ranging from non-productive cough to respiratory failure mainly due to pulmonary haemorrhage. Recognition of Weil’s disease in patients presenting with pulmonary symptoms can be difficult. This case illustrates a classic case of pulmonary haemorrhagic involvement in Weil’s disease.
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Vinetz, Joseph, Alyssa N. Chetrick, Katie E. Steimel, Carla E. Devillers, Jean-Louis Excler, Jerome H. Kim, and Suneth Agampodi. "Getting leptospirosis onto the lists of neglected tropical diseases." Open Access Government 43, no. 1 (July 8, 2024): 52–54. http://dx.doi.org/10.56367/oag-043-11310.

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Getting leptospirosis onto the lists of neglected tropical diseases Leptospirosis is a globally important infectious disease, but neglected to the extent that it’s not on WHO’s or FDA’s neglected tropical diseases lists; this needs to change. Leptospirosis, caused by spirochetes of the bacterial genus Leptospira, poses a significant yet poorly recognized global public health threat. Incomprehensibly, this disease remains neglected by the global health agenda. Leptospirosis is estimated to cause more than a million cases and over 60,000 deaths annually, with case fatality rates of up to 20%. (1) Hence, leptospirosis is the most important zoonotic bacterial disease worldwide. It is common in tropical regions of low- and middle-income countries such as Brazil, India, China, Indonesia, Peru, Sri Lanka, and Thailand, and it affects high-income countries, too, including the United States and Europe.
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Levett, Paul N. "Leptospirosis." Clinical Microbiology Reviews 14, no. 2 (April 1, 2001): 296–326. http://dx.doi.org/10.1128/cmr.14.2.296-326.2001.

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SUMMARY Leptospirosis is a worldwide zoonotic infection with a much greater incidence in tropical regions and has now been identified as one of the emerging infectious diseases. The epidemiology of leptospirosis has been modified by changes in animal husbandry, climate, and human behavior. Resurgent interest in leptospirosis has resulted from large outbreaks that have received significant publicity. The development of simpler, rapid assays for diagnosis has been based largely on the recognition that early initiation of antibiotic therapy is important in acute disease but also on the need for assays which can be used more widely. In this review, the complex taxonomy of leptospires, previously based on serology and recently modified by a genotypic classification, is discussed, and the clinical and epidemiological value of molecular diagnosis and typing is also evaluated.
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Rahayu, Ingrit Ridha. "PEMODELAN MATEMATIKA PENYEBARAN PENYAKIT LEPTOSPIROSIS DENGAN PENGARUH TREATMENT." Journal of Mathematics UNP 7, no. 1 (March 30, 2022): 28. http://dx.doi.org/10.24036/unpjomath.v7i1.10923.

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Leptospirosis is a disease caused by bacteria and attack humans and animals. Leptospirosis transmitted from human to human, from animal to animal, from animal to human. In this study, a mathematical model transmitted of Leptospirosis disease with the effect of treatment. The purpose of this modelling is to determine the spread of Leptospirosis disease with the effect of treatment, to determine analysed of mathematical model spread of Leptospirosis disease with the effect of treatment, and to determine interpretation of mathematical model spread of Leptospirosis disease with the effect of treatment. This research begins by determining the variables, parameters, and assumptions related to the problem so that the mathematical model spread of Leptospirosis disease with the effect of treatment. After that model will be analyzed and interpreted. Based on the result of the analysis showed that this model is stable which shows that the point care remains disease-free.
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Dissertations / Theses on the topic "Leptospirosis disease"

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Yan, Ke-Ting. "Aspects of immunity to Leptospira borgpetersenii serovar hardjo." Thesis, Queen's University Belfast, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387931.

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del, Valle-Mendoza Juana, Carlos Palomares-Reyes, Hugo Carrillo-Ng, Yordi Tarazona-Castro, Sungmin Kym, Miguel Angel Aguilar-Luis, Valle Luis J. Del, et al. "Leptospirosis in febrile patients with suspected diagnosis of dengue fever." BioMed Central Ltd, 2021. http://hdl.handle.net/10757/657332.

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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
Objective: This study was carried out to determine the prevalence of leptospirosis among febrile patients with a suspicious clinical diagnosis of dengue fever in northern Peru. Results: A total of 276 serum samples from patients with acute febrile illness (AFI) and suspected diagnosis for dengue virus (DENV) were analyzed. We identified an etiological agent in 121 (47.5%) patients, DENV was detected in 30.4% of the cases, leptospirosis in 11.2% and co-infection by both pathogens was observed in 5.9% of the patients. In this study the most common clinical symptoms reported by the patients were: headache 89.1%, myalgias 86.9% and arthralgias 82.9%. No differences in symptomatology was observed among the different study groups.
National Research Foundation of Korea
Revisión por pares
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Soares, Luciane Marieta. "O uso da talidomida como terapia adjuvante na leptospirose experimental." reponame:Repositório Institucional da FIOCRUZ, 2013. https://www.arca.fiocruz.br/handle/icict/7524.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2014-04-22T16:33:20Z No. of bitstreams: 1 Luciane Marieta Soares O uso da talidomida...2013.pdf: 1032465 bytes, checksum: 705c1f8374aee3a4f8a1b0f537cd33f6 (MD5)
Made available in DSpace on 2014-04-22T16:33:21Z (GMT). No. of bitstreams: 1 Luciane Marieta Soares O uso da talidomida...2013.pdf: 1032465 bytes, checksum: 705c1f8374aee3a4f8a1b0f537cd33f6 (MD5) Previous issue date: 2013
Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
A leptospirose é uma zoonose de importância global, causada por leptospiras patogênicas. Seu tratamento é limitado quando iniciado após quatro dias do surgimento de sintomas, portanto, novas terapias adjuvantes são necessárias. Objetivo. Testar a droga imunomoduladora talidomida como terapia adjuvante à ampicilina no modelo de tratamento tardio da leptospirose experimental em hamsters. Métodos. 60 hamsters foram infectados via intraperitoneal por Leptospirainterrogans cepa L1-130, e foram separados em grupos: nenhum tratamento (NONE), talidomida (TAL), ampicilina (AMP) e ambos (AMP-TAL). A talidomida foi administrada via sonda orogástrica na dosagem de 50 mg/Kg diluída em óleo de linhaça (2ml/Kg) por três dias. Já a ampicilina por via intramuscular: 100mg/Kg/bid por seis dias. Foram realizados dois desenhos experimentais. Experimento 1: o tratamento foi iniciado 48h após o início dos sinais clínicos da doença. Experimento 2: o tratamento foi iniciado imediatamente após a detecção do primeiro óbito entre os animais infectados. Resultados. Experimento1: todos os hamsters dos grupos AMP e AMP-TAL sobreviveram (n=8) enquanto todos os animais dos grupos NONE (n=6) e TAL (n=8) morreram. Os hamsters dos grupos AMP e AMP-TAL não mostraram lesões renais, pulmonares ou hepáticas. Baixa carga de leptospiras foi detectada nos órgãos alvo. Experimento 2: o desfecho letal foi observado em 6/6 hamsters no grupo NONE, 8/8 do grupo TAL, 6/8 do AMP e 6/8 do AMP-TAL. A talidomida usada como adjuvante não prolongou a sobrevida dos animais tratados com ampicilina. No entanto, o grupo TAL apresentou sobrevida mais longa que o grupo que não recebeu tratamento algum. Os animais tratados apresentaram maior frequência de destrabeculação de hepatócitos. Conclusão: Esse estudo abre novas perspectivas no desenvolvimento de um tratamento tardio na leptospirose, contudo observou-se que a talidomida utilizada como terapia adjuvante não teve impacto na sobrevida de hamsters como modelo de início tardio de terapia antimicrobiana.
Leptospirosis is a zoonosis of global importance, caused by pathogenic leptospira. His treatment is limited when started after four days of onset of symptoms, increasing the risk of morbidity and mortality, so new adjuvant therapies are needed.Objectives.To test the immunomodulatory drug, thalidomide, as an adjuvant therapy to antibiotics in experimental leptospirosis. Methods. Hamsters were infected by Leptospirainterrogans strain L1-130, and groups were assigned based on no treatment (NONE), thalidomide only (TAL), ampicillin only (AMP) or both (AMP-TAL). Thalidomide was administered via a gastric tube: 50 mg/kg in linseed oil and 2 ml/kg for three days. Ampicillin was administered intramuscularly at the rate of 100 mg/kg/bid for six days. Treatment was started two days after the onset of symptoms (experiment 1) and immediately after detection of the first death (experiment 2). Results. Experiment 1: all hamsters from the groups AMP and AMP-TAL survived (n=8), while all hamsters from groups NONE (n=6) and TAL (n=8) died. The AMP and the AMP-TAL groups showed no renal, lung or liver pathology and absent or very low leptospiral burden in target organs. Experiment 2: lethal outcome was observed in 6/6 hamsters in the NONE group, 8/8 in the TAL group, and 6/8 in the AMP group and the AMP-TAL group. Thalidomide showed no survival benefit when compared to hamsters treated with ampicillin alone. The TAL group, however, had a longer interval between infection and death when compared to the NONE group. Treated animals had a higher frequency of liver plate disarray. The TAL, AMP and AMP-TAL groups had very low tissue leptospiral counts. Conclusion: This study may open new perspectives to assist the development of a delayed treatment in leptospirosis, however it was observed that thalidomide used as adjuvant therapy had no impact on the survival of hamsters as late onset of antimicrobial therapy model.
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Santos, Adriana Maria Amurete Roque dos. "Leptospirose canina : estudo retrospetivo sobre a relação entre as alterações hematológicas, achados ecográficos e desfecho clínico." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2021. http://hdl.handle.net/10400.5/21233.

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Dissertação de Mestrado Integrado em Medicina Veterinária
O estudo retrospetivo desenvolvido teve como objetivo caraterizar uma amostra de canídeos infetados com Leptospira spp., comparando os resultados obtidos com os descritos pela bibliografia disponível e, ainda, verificar se existem associações entre as alterações he matológicas, os achados ecográficos e o desfecho clínico dos casos. A amostra do presente estudo é constituída por 17 cães diagnosticados com leptospi rose no Hospital Veterinário do Atlântico durante um período de quatro anos. As alterações analíticas mais frequentemente observadas na amostra incluem as con centrações elevadas de ureia (n=17), creatinina (n=17), FAS (n=14) e ALT (n=9), bem como a presença de leucocitose (n=11), neutrofilia (n=10) e trombocitopenia (n=10). Todos os animais apresentaram alterações ao exame ecográfico, sendo as mais fre quentes o aumento da ecogenecidade do córtex renal (n=10), renomegalia (n=8) e hepato megalia (n=8). Durante a hospitalização quase metade dos animais desenvolveram um quadro de infeção respiratória (n=8), verificando-se que a principal causa de morte dos animais deste estudo foi o desenvolvimento de hemorragia pulmonar (n=5). É possível concluir que os resultados obtidos neste estudo apresentam uma elevada concordância com os resultados descritos por outros autores, porém não se verificou a exis tência de correlações entre as alterações analíticas, achados ecográficos e o desfecho clínico dos casos.
ABSTRACT - Canine Leptospirosis: a retrospective study on the relation between haemato logical alterations, ultrasonography findings and clinical outcome - The aim of this study is to characterize, retrospectively, the data of dogs diagnosed with Leptospira spp. and compare the results with the current literature. Furthermore, to com pare the haematological alterations, ultrasonography findings and clinical outcomes of the dif ferent cases. The sample group consisted of 17 dogs diagnosed with leptospirosis at the Hospital Veterinário do Atlântico in the last four years. High concentrations of urea (n=17), creatinine (n=17), ALP (n=14) and ALT (n=9) were the most common laboratorial findings in the sample group, as well as leucocytosis (n=11), neutrophilia (n=10) and thrombocytopenia (n=10). Ultrasonography abnormalities were found in all the dogs, namely an increase in the echogenicity of the renal cortex (n=10), renomegaly (n=8) and hepatomegaly (n=8). During hospitalization, nearly half of the sample group developed respiratory symp toms/infection (n=8), which lead to the main cause of death, pulmonary haemorrhage (n=5). In conclusion, the results from this study are in concordance with results obtained from previous studies. On the other hand, no correlation was found between the haematological alterations, ultrasonography findings and clinical outcomes of the cases.
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Gallego-Beltran, Juan Fernando. "Leptospirosis in Columbian dairy cattle : microbiological, serological, molecular and epidemiological aspects of the disease." Thesis, Royal Veterinary College (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272308.

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Москалюк, В. Д., М. О. Андрущак, and І. В. Баланюк. "Клініко-епідеміологічна характеристика перебігу лептоспірозу у хворих на Буковині." Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/45570.

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Лептоспіроз – гостре інфекційне захворювання, зооноз, спричинене різними типами лептоспір. Серед особливо небезпечних природно-осередкових хвороб лептоспіроз залишається єдиною інфекцією, що реєструється і має тенденцію до зростання на всіх адміністративних територіях України щороку.
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Голяр, О. І., and Д. М. Шпарик. "Епідеміологічні особливості лептоспірозу в Україні." Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/45402.

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Лептоспіроз – це поширене захворювання у всіх країнах світу, окрім Арктики. В Україні лептоспіроз реєструється в усіх регіонах. Більше половини випадків протікає у тяжкій формі та потребує реанімаційних заходів.
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Biscornet, Leon. "Leptospirosis in the Seychelles : geographic, molecular and epidemiological investigations of a zoonotic disease in a tropical insular environment." Thesis, La Réunion, 2020. http://www.theses.fr/2020LARE0013.

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La leptospirose est une maladie négligée émergente touchant plus particulièrement les régions tropicales, et plus encore les îles tropicales telles que les Seychelles, qui enregistrent des incidences humaines parmi les plus élevées au monde. Cette thèse a pour objectifs d’explorer l’éco épidémiologie de la leptospirose aux Seychelles (i) en utilisant les rats comme marqueurs d’exposition environnementale, (ii) en décrivant l’épidémiologie moléculaire de la maladie chez l’homme et l’animal à travers une approche “One Health”, et enfin (iii) en identifiant les comportements et professions à risque tout en en comparant la situation actuelle à celle décrite il y a 25 ans. La combinaison d’approches géographique, moléculaire et clinique vise à dresser un tableau complet de la situation épidémiologique de cette maladie aux Seychelles en intégrant les réservoirs animaux, l’homme et l’environnement qu’ils occupent.La fragmentation de l’habitat et la proximité de ressources alimentaires apparaissent comme de bons prédicteurs d’infection chez les rats. Les analyses géo-spatiales permettent de mettre en évidence d’autres variables corrélées négativement (altitude ou distance à un point d’eau douce) ou positivement (niveau d’urbanisation, pluviométrie) au statut d’infection chez les rats. Ces résultats pourraient être pris en compte dans les politiques d’aménagement du territoire mises en place dans des buts de conservation des habitats ou de contrôle des rongeurs, afin de réduire l’exposition de l’homme à des pathogènes maintenus dans l’environnement par les rats. Si le niveau d’urbanisation est positivement corrélé avec le statut d’infection, ce patron pourrait au moins en partie résulter de la distribution des deux espèces Rattus norvegicus et Rattus rattus. En effet la première espèce, retrouvée essentiellement en milieu urbain, est nettement plus infectée que la deuxième que l’on retrouve partout sur l’île. Néanmoins, la comparaison des leptospires retrouvés chez les rats et chez les cas humains graves indique que les rats ne sont impliqués que dans un tiers des transmissions à l’homme, la majorité des cas humains étant causée par des leptospires dont le(s) réservoir(s) reste(nt) à identifier. Une incidence annuelle de 54,6 (95% IC 40,7-71,8) pour 100 000 habitants confirme l’importance médicale majeure de cette maladie dans le pays. La maladie touche très majoritairement les hommes (96%) et présente un taux de mortalité élevé (11,2%), essentiellement associé à des formes sévères (dysfonctions rénales et hépatiques, hémorragie pulmonaire). Les activités agricoles et le jardinage, la proximité d’élevages et de chats, une thrombocytopénie, une leucocytose, un taux de bilirubine élevé et des valeurs élevées aux tests de fonction rénale sont de bons prédicteurs de leptospirose. La distribution géographique des cas humains ne correspond pas à celle des districts hébergeant des populations de rats aux prévalences d’infection élevées, en cohérence avec un rôle restreint des rats dans la leptospirose humaine.La comparaison des données présentées ici avec celles publiées il y a 25 ans révèle un changement dans les comportements et les expositions, et montre qu’une meilleure prise en charge hospitalière a vraisemblablement contribué à faire diminuer la mortalité liée à la leptospirose, même si celle-ci reste élevée. Un faible niveau de connaissance de la maladie en population générale souligne l’importance de mettre en place des campagnes de sensibilisation. Les données produites dans le cadre de cette thèse stimulent la mise en place d’études complémentaires visant à mettre en évidence le(s) réservoir(s) complémentaire(s) et adapter les mesures de prévention pour limiter le fardeau que représente cette maladie aux Seychelles, aujourd’hui encore reconnue comme la maladie infectieuse causant le plus de décès dans le pays
Leptospirosis is an emerging neglected disease representing a heavy burden in the tropics, especially in tropical islands such as Seychelles, which record among the highest human incidence worldwide. This thesis aims at exploring the eco-epidemiology of leptospirosis in Seychelles by (i) using rats as markers of environmental exposure to Leptospira infection, (ii) describing the molecular epidemiology of the disease in humans and animals in a One Health framework, and (iii) identifying occupational and behavioural risk factors while comparing the current situation to that described 25 years ago. The combination of fine spatial distribution, molecular and clinical epidemiology complement each other in providing a comprehensive picture of the continuum involving reservoirs and human hosts within a shared environment.Habitat fragmentation and proximity to nutritional sources are found good predictors of Leptospira-laden Rattus spp. Geospatial analyses determined a selection of other important variable factors that are strongly correlated with Leptospira infection in Rattus spp., including altitude or distance to surface water (negative correlation), urbanization and heavy rainfall (positive correlation). Results of these analyses can guide policy makers and especially urban planners to best implement landscape structures for conservation or pest control goals leading to reduced exposure of humans to rat-borne diseases.Rattus norvegicus is found significantly more infected than Rattus rattus. Therefore, increased infection in urbanized/fragmented habitats may result at least in part from Rattus spp distribution, as R. norvegicus is mostly found in urban areas. Most importantly, genotyping of Leptospira in human acute cases and rats suggests that these rodents are involved in only a third of human acute infections, while most human cases originate from yet to be identified reservoir(s).An annual incidence of 54.6 (95% CI 40.7-71.8) per 100,000 confirms the major medical and public health importance of the disease in the country. The disease affects mainly men (96%) and displays a case fatality rate of 11.2%, mostly associated with severe forms (acute renal failure, hepatic failure and pulmonary haemorrhage). Farming and gardening related activities, proximity to cattle and cats, thrombocytopaenia, leukocytosis, elevated bilirubin and high values for renal function tests are predictors of leptospirosis. The geographical distribution of human cases poorly overlaps districts of high prevalence in rats in keeping with a restricted role of rats in human disease.The comparison of figures reported herein and in previous studies published 25 years ago reveals changes in behaviour and exposure, and shows that the development of health care has lowered the case fatality despite still high disease incidence in the country. A low level of knowledge on leptospirosis is reported, urging the need for implementing health education campaigns. Altogether, the data presented in this thesis strongly supports the implementation of a research program aiming at discovering alternative reservoir(s) to provide a full understanding of the epidemiological situation, which will allow fine tuning preventive measures for an efficient control of a disease that is still recognised as the infectious disease causing the highest mortality in the country
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Araújo, Wildo Navegantes de. "Aspectos epidemiológicos da leptospirose no Brasil, 2000 a 2009 e a avaliação do conhecimento e das atitudes sobre a doença em uma favela na cidade de Salvador, Bahia." reponame:Repositório Institucional da FIOCRUZ, 2010. https://www.arca.fiocruz.br/handle/icict/4324.

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Made available in DSpace on 2012-09-04T18:27:25Z (GMT). No. of bitstreams: 1 Wildo Navegantes Aspectos epidemiologicos da leptospirose....pdf: 1357912 bytes, checksum: 01380ce81c921e78d62f63cce2d77036 (MD5) Previous issue date: 2010
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil
A leptospirose é a principal doença infecciosa zoonótica em áreas urbanas nos países em desenvolvimento, porém subnotificada. O conhecimento e as atitudes sobre a leptospirose é desconhecida nas comunidades brasileiras onde a doença é prevalente. Objetivos: 1) Descrever os casos notificados de leptospirose, fatores de risco para óbito, influência das chuvas em cidades metropolitanas e parte da carga da leptospirose no Brasil, 2000-2009. 2) Descrever o conhecimento e as atitudes sobre leptospirose dos moradores de uma favela na cidade de Salvador. Métodos:1) Foram descritos os casos notificados de leptospirose no Sistema Nacional de Vigilância de 2000 a 2009. Foi analisada a influência das chuvas e a ocorrência de casos de leptospirose em cinco metrópoles brasileiras. Foram calculadas as taxas de incidência, hospitalização, mortalidade e letalidade por leptospirose e foram avaliados os fatores de risco para óbito a partir das variáveis demográficas entre os casos confirmados. 2) Foi conduzido um estudo transversal sobre o conhecimento e atitudes sobre leptospirose na comunidade de Pau da Lima, Salvador – Bahia. Resultados: 1) A doença acomete populações vulneráveis socialmente que vivem em áreas urbanas. As taxas de incidência, hospitalização, mortalidade e letalidade foram 1,48, 1.04, 0,12 por 100.000 habitantes e 9%, respectivamente. A partir de 15 anos de idade (OR=1,88; IC95% 1,39-2,55), baixo nível educacional (OR=1,35; IC95% 1,17-1,56), viver em área urbana (OR=2,19; IC95% 1,80-2,69) foram detectados como fatores de risco para óbito entre os casos confirmados. As chuvas tiveram forte relação com a ocorrência de surtos sazonais da doença em cinco cidades metropolitanas. 2) 72,7% das pessoas sabem que a leptospirose é uma doença transmitida por ratos, 56,4% reconhecem que pegam a doença com o contato com urina de ratos, 17,8% referiram limpar esgotos ao redor da sua casa, 35,5% referiram usar luvas e 33,3% botas para se proteger. Conclusão: No Brasil, a doença acomete homens adultos, com baixa nível educacional que vivem em áreas urbanas, tais achados estão associados a óbitos. Muitos surtos sazonais ocorreram sob influência das chuvas nas cidades metropolitanas estudadas. Na comunidade de Pau da Lima, uma favela de Salvador, as pessoas conhecem a leptospirose e as principais atitudes detectadas estão relacionadas as contínuas exposições a água de chuvas e esgotos na comunidade. As conclusões deste trabalho apontam para a necessidade de estruturar serviços de saúde que antecedam as chuvas, e para obras de saneamento básico em regiões metropolitanas com maior incidência da doença. Recomendamos que sejam realizados outros estudos sobre o conhecimento em relação a leptospirose para entender os déficits de informação da população, assim como instruí-los para organizadamente cobrarem soluções como obras de saneamento básico que minimizem o impacto da leptospirose na população.
The leptospirosis is major zoonotic infectious disease in urban areas in the developing countries. However, the leptospirosis is underreported in the world. The knowledge and attitudes about leptospirosis of the communities which suffer due the leptospirosis is unavailable. Objectives 1) To describe the leptospirosis cases reported, risk factors for death, influence of the rainfalls in metropolitan cities and, part of the burden caused by the leptospirosis in Brazil from 2000 through 2009. 2) To describe the knowledge and attitudes about leptospirosis in slum area in metropolitan city of the Brazil. Methods: 1) Were described the leptospirosis cases reported in the National Surveillance System from 2000 to 2009. Were analyzed the influence of the rainfalls in metropolitan cities, were analyzed frequency measures and, were identified risk factors for death. 2) Was conducted a cross-section study about the knowledge and attitudes about leptospirosis in the community of “Pau da Lima”, Salvador- Bahia. Results: 1) The disease attacks adult men in economically active age with low educational level living in urban areas. Incidence, hospitalization, mortality and lethality rates were 1.48, 1.04, 0.12 per 100.000 inhabitants, and 9% respectively. Being aged 15 or above (OR=1.88; IC 95% 1.39-2.55), having low educational level (OR=1.35; IC 95% 1.17-1.56), and living in urban areas (OR=2.19; IC 95% 1.80-2.69) have been detected as risk factors for death among the confirmed cases. Rains were strongly related to the occurrence to seasonal outbreaks of the disease in five metropolitan cities studied. 2) In an urban slum in Salvador, 72.7% of the individuals know that leptospirosis is a disease transmitted by rats, 56.4% recognized that the disease can be contracted by getting in contact with the urine of rats, 17.8% clean the sewers surrounding their houses, 35.5% wear gloves and 33.3% wear boots to protect them. Conclusion: In Brazil, the disease attacks adult men with low educational level living in urban areas, these covariates are associated to death. Many seasonal outbreaks occur in the studied metropolitan cities under the influence of rain. In a slum area in Salvador, people know leptospirosis and the main attitudes detected are related to continuous exposition of the community to rainfalls and sewers. Health policies geared to structuring health services prior to rains and the implementation of basic sanitation infrastructure to be requirements for minimizing the occurrence of leptospirosis in mega cities. We also recommend the conduction of studies on the knowledge and attitudes in order to understand population’s information deficit, as well as to instruct them to demand solutions such as the construction of basic sanitation infrastructure in an orderly manner.
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JÃnior, Geraldo Bezerra da Silva. "ManifestaÃÃes clinicas,classificaÃÃo da lesÃo renal aguda e fatores de risco para Ãbito em pacientes com a forma grave de leptospirose." Universidade Federal do CearÃ, 2010. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13163.

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CoordenaÃÃo de AperfeÃoamento de Pessoal de NÃvel Superior
IntroduÃÃo. A leptospirose à uma doenÃa endÃmica no Nordeste, sendo caracterizada por complicaÃÃes potencialmente fatais como a lesÃo renal aguda (LRA). O objetivo deste estudo foi avaliar as manifestaÃÃes clÃnicas, a classificaÃÃo da LRA e os fatores de risco para Ãbito em pacientes com a forma grave de leptospirose. MÃtodos. Foi realizado estudo retrospectivo em pacientes com a forma grave de leptospirose internados em hospitais terciÃrios na cidade de Fortaleza, nordeste do Brasil. Foram avaliadas as manifestaÃÃes clÃnicas, os exames laboratoriais na admissÃo e durante a internaÃÃo e o tratamento instituÃdo. LRA foi definida de acordo com as classificaÃÃes RIFLE e AKIN, sendo comparados os pacientes nas diferentes classes. Foram comparados os pacientes que usaram com aqueles que nÃo usaram penicilina, assim como os pacientes que sobreviveram com os que foram a Ãbito. AnÃlises univariada e multivariada foram usadas para a investigaÃÃo dos fatores de risco para Ãbito. A anÃlise estatÃstica foi feita pelo programa SPSS versÃo 10.0. Resultados. Foram incluÃdos 287 pacientes, com mÃdia de idade de 36,8Â15,6 anos, sendo 80,8% do sexo masculino. Os principais sinais e sintomas apresentados foram febre (96,2%), mialgia (90,6%), icterÃcia (85,7%), cefaleia (74,2%), vÃmitos (70,7%), desidrataÃÃo (54%) e calafrios (53,7%). LRA foi observada em 237 pacientes (82%) pelo critÃrio RIFLE e 242 (84%) pelo AKIN. A mortalidade geral foi de 13%. A mortalidade foi semelhante nos pacientes que usaram e que nÃo usaram penicilina (11,6% vs. 13,7%, p=0,60). Aumento da mortalidade foi observado de acordo com as piores classificaÃÃes: RIFLE-R (2%), RIFLE-I (8%) e RIFLE-F (23%), assim como AKIN 1 (2%), AKIN 2 (8%) e AKIN 3 (23%), p < 0,0001. Os pacientes com oligÃria tiveram maior mortalidade (20%), em comparaÃÃo com os pacientes sem oligÃria (5%), p=0,02. Os fatores de risco independentes para Ãbito foram: RIFLE-F (OR=10,5, IC 95%=1,3-80,8, p<0,001), AKIN 3 (OR=7,5, IC 95%=2,2-25,2 p<0,001) e necessidade de diÃlise (OR=3,5, IC 95%=1,1-11,01, p=0,01). ConclusÃes. A LRA à uma complicaÃÃo frequente na leptospirose, com mortalidade significativa. Houve associaÃÃo entre as classificaÃÃes RIFLE e AKIN com a mortalidade na leptospirose. Os fatores de risco independentes para Ãbito sÃo classificaÃÃo RIFLE-F, AKIN 3 e necessidade de diÃlise.
Introduction. Leptospirosis is en endemic disease in Northeast of Brazil, which is characterized by potential fatal complications such as acute kidney injury (AKI). The aim of this study was to evaluate the clinical manifestations, the AKI classification and the risk factors for death in patients with the severe form of leptospirosis. Methods. A retrospective study was conducted in patients with severe form of leptospirosis admitted to tertiary hospitals in Fortaleza city, Northeast of Brazil. The clinical manifestations, laboratory tests at admission and during hospital stay, as well as treatment, were evaluated. AKI was defined according to the RIFLE and AKIN classifications, and the patients in each category were compared. Patients who used and who did not use penicillin, as well as survivors and non-survivors, were compared. Univariate and multivariate analysis were performed to investigate the risk factors for death. Statistical analysis was done with SPSS program version 10.0. Results. A total of 287 patients were included, with a mean age of 36.8Â15.6 years, and 80.8% were male. The main signs and symptoms at admission were fever (96.2%), myalgia (90.6%), jaundice (85.7%), headache (74.2%), vomiting (70.7%), dehydration (54%) and chills (53.7%). AKI was observed in 237 patients (82%) according to the RIFLE criteria and 242 (84%) according to AKIN. General mortality was 13%. Mortality was similar in patients who used and who did not use penicillin (11.6% vs. 13.7%, p=0.60). An increase in mortality was observed according to the worst classifications of RIFLE and AKIN: RIFLE-R (2%), RIFLE-I (8%) e RIFLE-F (23%), AKIN 1 (2%), AKIN 2 (8%) e AKIN 3 (23%), p<0.0001. Patients with oliguria had a higher mortality (20%), when compared to those without oliguria (5%), p=0.02. Independent risk factors for death were: RIFLE-F (OR=10.5, 95% CI=1.3-80.8, p<0.001), AKIN 3 (OR=7.5, 95% CI=2.2-25.2 p<0.001) and need of dialysis (OR=3.5, 95% CI=1.1-11.01, p=0.01). Conclusions. AKI is a frequent complication in leptospirosis, with significant mortality. There was association between RIFLE and AKIN classifications with mortality. Independent risk factors for death were RIFLE-F, AKIN 3 and need of dialysis.
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Books on the topic "Leptospirosis disease"

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Ireland. Food Safety Advisory Committee. Leptospiral infections, Lyme disease, Babesiosis, Orf virus disease. Dublin: Stationery Office, 1992.

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Leonard, Nola. Leptospirosis in cattle: Infection and control. [Dublin]: Teagasc, 1997.

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Leonard, Nola. Leptospirosis in cattle: Infection and control. [Dublin]: Teagasc, 1991.

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Burdmann, Emmanuel A. Leptospirosis. Edited by Vivekanand Jha. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0191.

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Leptospirosis is one of the most prevalent zoonotic diseases worldwide. Pathogenic spirochaetes are shed in the urine of infected mammals to the environment. Humans are infected through contact with contaminated material. Leptospirosis is more prevalent in tropical and subtropical areas, but exists in all continents except Antarctica. The disease is difficult to diagnose and hence frequently neglected. Its clinical picture ranges from a mild flu-like disease to a life-threatening form with pulmonary haemorrhage, liver failure and acute kidney injury (AKI), called Weil disease, which may affect 10% of those with clinical disease. Typically, fever, myalgia and headache progress to nausea and vomiting, jaundice, red eyes, and other manifestation affecting skin, brain, and other organs.Kidney involvement, characterized by acute tubulointerstitial nephritis, is nearly universal. It may be clinically manifested as a tubulopathy with urinary electrolytes wasting, hypokalaemia and hypomagnesaemia and/or as AKI, which is more frequently non-oliguric. Antibiotic therapy may reduce hospitalization time and AKI frequency. Otherwise management is supportive, including timely and adequate dialysis support.
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Smith, Robert M., and Wendy J. Zochowski. Leptospirosis. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0027.

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Leptospirosis is one of the most widespread and important zoonotic pathogens and is of global medical and veterinary importance. Clinical disease ranges from mild self-limiting influenza – like illness to fulminating repeats-several failure.It is caused by bacterial spirochaetes of the genus Leptospira, family Leptospiraceae. Pathogenic Leptospira interrogans strains, of which there are over 230 serovars in 24 serogroups, are morphologically identical in that they are thin, helical highly motile Gram-negative bacteria, hooked at one or both ends.Natural hosts of pathogenic strains, generally referred to as serovars, may cause infection in man and include wild animals (rodents), livestock (cattle and pigs) and pets (dogs). Most, if not all mammals may become long-term carriers (maintenance hosts). Leptospires become located in the renal tubules and excreted in the urine of infected reservoir animals, humans becoming infected through broken skin, mucous membranes and the conjunctivae.Leptospirosis is most commonly found in tropical or sub-tropical countries in both urban and rural settings. It causes major economic losses, to the highly intensive cattle and pig industries in developed countries, primarily through their effects on reproduction. It is still an important occupational disease risk for people working in agriculture or those living in unsanitary conditions. It is increasingly recognised as a recreational and travel-associated disease.
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Clement, Jan. Acute kidney injury and hantavirus disease. Edited by Norbert Lameire. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0242_update_001.

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Hantavirus disease or at least its renal form, the so-called haemorrhagic fever with renal syndrome is the only globally emerging acute kidney injury (AKI) form, and currently without doubt the most underestimated form of community-acquired AKI. Hantavirus disease is a viral zoonosis, caused by inhalation of infectious aerosolized excreta from chronically infected rodents, which are both the reservoir and the vector of different hantavirus species. Clinical presentation consists of sudden flu-like symptoms (fever, headache, myalgia), followed by gastrointestinal discomfort and AKI, often with anuria or oliguria. More rarely, acute myopia and/or non-cardiogenic acute lung oedema or injury is the presenting or complicating symptom. Laboratory hallmarks are initial thrombocytopenia and proteinuria, raised C-reactive protein and lactate dehydrogenase, left-shift leucocytosis, and typical but transient serum lipid disturbances. Spontaneous remission occurs within 2–3 weeks without sequelae. Case fatality rate is between 0.1% and 15% according to the infecting hantavirus species, but most infections show in fact an asymptomatic or paucisymptomatic presentation. Treatment is only supportive, but may necessitate life-saving intensive care techniques. Together with leptospirosis, haemorrhagic fever with renal syndrome is the only form of AKI against which different vaccines are in use, but a World Health Organization-licensed hantavirus vaccine is still lacking.
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Cottle, Lucy, and Mike Beadsworth. Spirochaetal infection (non-syphilis). Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0312.

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Spirochaetes are slender, helical, Gram-negative rods. The group includes Treponema, Leptospira, and Borrelia. This chapter focuses on leptospirosis and Lyme disease. Discussion of the non-venereal treponematoses and relapsing fevers is beyond the scope of this text; they are rarely encountered in the UK.
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Dondorp, Arjen M. Other tropical diseases in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0294.

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A wide range of tropical infectious diseases can cause critical illness. Knowledge of the local epidemiology where the disease is acquired is essential. In addition, local resistance patterns of common bacterial pathogens can be very different in tropical countries, so that antibiotic regimens might need adaptation. The ‘surviving sepsis’ guidelines are not always appropriate for the treatment of tropical sepsis. Both diseases require a more restricted fluid management. Leptospirosis is another important tropical disease that can cause sepsis with liver and renal failure or ARDS with pulmonary haemorrhages. Neglected tropical diseases causing neurological syndromes include trypanosomiasis (Sub-Saharan Africa) and rabies. Several viruses in the tropics can cause encephalitis. Recent epidemics of respiratory viruses causing life-threatening pneumonia have had their origins in tropical countries, including severe acute respiratory syndrome, influenza A subtype H5N1 (‘avian influenza’), and recently Middle East respiratory syndrome coronavirus.
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Berger, Stephen, and Inc Gideon Informatics. Leptospirosis: Global Status. Gideon Informatics, Incorporated, 2022.

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Berger, Stephen, and Inc Gideon Informatics. Leptospirosis: Global Status. Gideon Informatics, Incorporated, 2021.

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Book chapters on the topic "Leptospirosis disease"

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Hussein, Mansour F. "Leptospirosis (Weil’s Disease)." In Infectious Diseases of Dromedary Camels, 143–46. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79389-0_22.

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Wang, Guiqing, and Maria E. Aguero-Rosenfeld. "Lyme Disease, Relapsing Fever, and Leptospirosis." In Manual of Molecular and Clinical Laboratory Immunology, 419–32. Washington, DC, USA: ASM Press, 2016. http://dx.doi.org/10.1128/9781555818722.ch47.

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Bolin, Carole. "Leptospirosis." In Emerging Diseases of Animals, 185–200. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818050.ch9.

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Faine, S. "Leptospirosis." In Laboratory Diagnosis of Infectious Diseases, 344–52. New York, NY: Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3898-0_35.

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Lichtenstein, Daniel, and Joseph Domachowske. "Leptospirosis." In Introduction to Clinical Infectious Diseases, 393–99. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-91080-2_37.

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Domachowske, Joseph, and Manika Suryadevara. "Leptospirosis." In Clinical Infectious Diseases Study Guide, 319–23. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-50873-9_52.

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Li, Ruili, Hongjun Li, and Aidong Zhang. "Leptospirosis." In Radiology of Infectious Diseases: Volume 2, 143–60. Dordrecht: Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-017-9876-1_14.

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Jyothi, J., and M. Bhavya Sree. "Leptospirosis." In The Handbook of Zoonotic Diseases of Goats, 232–35. GB: CABI, 2024. http://dx.doi.org/10.1079/9781800622852.0019.

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Grassmann, André Alex, Carlos Eduardo Pouey da Cunha, Everton Burlamarque Bettin, and Alan John Alexander McBride. "Overview of Leptospirosis." In Neglected Tropical Diseases, 245–75. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-68493-2_8.

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Lau, Colleen L. "Human Leptospirosis in Oceania." In Neglected Tropical Diseases, 177–92. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-43148-2_7.

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Conference papers on the topic "Leptospirosis disease"

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Sholikah, Sholikah, Atik Choirul Hidajah, and Bambang Wuryono Kartika. "Evaluation of an Epidemiologic Investigation and Risk Factors Study of Leptospirosis Disease." In The 2nd International Symposium of Public Health. SCITEPRESS - Science and Technology Publications, 2017. http://dx.doi.org/10.5220/0007515004090413.

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Rafiq, M., M. S. Arif, A. Raza, and Humaira Ejaz. "Numerical Modeling for Transmission dynamics of Leptospirosis Disease in Juvenile and Adult Humans." In 2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST - 2019). IEEE, 2019. http://dx.doi.org/10.1109/ibcast.2019.8667118.

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Sinaga, Mikha Dayan, Frinto Tambunan, Charles Jhony Mantho Sianturi, Andrian Syahputra, Fithry Tahel, and Siti Aliyah. "An Expert System for Diagnosing Leptospirosis Disease Using Forward Chaining and Bayes Theorem." In 2019 7th International Conference on Cyber and IT Service Management (CITSM). IEEE, 2019. http://dx.doi.org/10.1109/citsm47753.2019.8965338.

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Cerrud-Rodriguez, R. C., T. Halasa, C. Epstein, I. M. Fernandez, and O. Ariyibi. "An Intriguing Presentation of an Infrequent Disease - A Case Report of Urban Leptospirosis in the Bronx." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6912.

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Korchemny, N., H. Allos, O. Teixeira Peixoto, and A. Moraco. "Extensive Bilateral Pulmonary Nodular Disease: A Rare Case of Leptospirosis With Widespread Pulmonary Involvement in New England." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5628.

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Tateishi, Simone, and Werner Peter Marcon. "Immunization and deworming of cattle, horses, canines and domestic felines." In VI Seven International Multidisciplinary Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/sevenvimulti2024-059.

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Abstract:
This expanded abstract addresses the importance of health management in Veterinary Medicine, emphasizing vaccine prophylaxis and deworming in horses, cattle, dogs and cats. Health management aims to prevent diseases such as Equine Influenza, Encephalomyelitis, Tetanus, Rhinopneumonitis, Rabies and Leptospirosis, which are relevant to public healthand the efficiency of treatments
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Vannaprathip, Narumol, Chanatda Tungwongjulaniam, Wimwiga Sakchainanon, Chadaporn Phiancharoen, Kasidet Suttiphatanan, Nopparuj Insawan, Itthiphon Mungetvit, and Jirattha Kiatmonkong. "A Conceptual Framework for Gamification in Teaching Decision-Making to Control Diseases - Melioidosis and Leptospirosis." In 2023 IEEE 12th Global Conference on Consumer Electronics (GCCE). IEEE, 2023. http://dx.doi.org/10.1109/gcce59613.2023.10315288.

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Reports on the topic "Leptospirosis disease"

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Wainaina, Martin, Joseph Wasonga, and Elizabeth Anne Jessie Cook. Epidemiology of human and animal leptospirosis in Kenya: A systematic review and meta-analysis of disease occurrence, serogroup diversity and risk factors. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2024. http://dx.doi.org/10.37766/inplasy2024.7.0097.

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